Cheap flights from Philadelphia to Greenville from $120

The month of January is another great option to travel to Greenville, with average flight prices from Philadelphia averaging around $463.

According to our data, Wednesday is the cheapest day to fly to Greenville from Philadelphia. The lowest ticket price found for a Wednesday departure recently was $457. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $723. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

Our most recent data shows that the best time of day to fly to Greenville is at noon. Flights from Philadelphia to Greenville during this time can be as low as $478. Flights to Greenville are more costly in the morning, with an average ticket price of $528. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Philadelphia to Greenville for the best Philadelphia - Greenville flight prices

You are more likely to see cheaper flights to Greenville from Philadelphia when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $522 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Philadelphia for as low as $443 on momondo.

There are 3 cabin classes available to choose from on Philadelphia to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 57% on your flight if you consider stops on a Philadelphia to Greenville flight.

As of October 2026, prices for Philadelphia to Greenville flights are approximately 189% more expensive when compared to flights at the same time last year.

Southwest is the most popular carrier operating from Philadelphia to Greenville

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Greenville from Philadelphia according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 6 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

2 flights are operational daily from Philadelphia to Greenville as of October 2026. The most popular departure time for this route is 5:00PM, with 65% of flights per day taking off in the afternoon.

As of October 2026, there are 18 flights per week flying from Philadelphia to Greenville. The most common day of the week flights depart is Thu, with 33% of flights taking off on this day.