Cheap flights from Panama to Massachusetts from $304

In general, August is the cheapest month to fly from Panama to Massachusetts. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $517. If you aren’t able to travel to Massachusetts during the month of August, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $567.

According to our data, Monday is the cheapest day to fly to Massachusetts from Panama. The lowest ticket price found for a Monday departure recently was $575. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Tuesday is the most expensive day to depart from Panama because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $642.

Our data shows that the cheapest Panama to Massachusetts flights are usually those with departure times in the morning. Our users have found flights to Massachusetts in the morning for as low as $581. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $594 on average. Flights to Massachusetts from Panama in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Panama City Tocumen Intl to Boston Logan Intl for the best Panama - Massachusetts flight prices

You are more likely to see cheaper flights to Massachusetts from Panama when booking weeks ahead of your departure date. In general, you can expect to find flights to Massachusetts for around $617 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Massachusetts from Panama for as low as $427 on momondo.

There are 2 cabin classes available to choose from on Panama to Massachusetts flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

The number of flights available between Panama and Massachusetts is 2 per day as of April 2026. The most frequent departure time is 4:00PM, with 100% of daily flights leaving in the afternoon.

19 flights are operational weekly from Panama to Massachusetts as of April 2026. The most popular departure day for this route is Fri, with 21% of flights per week taking off on this day.