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Cheap flights from Panama City to Chicago from $207

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Multiple Airlines Logo
2:55 pm - 9:22 amPTY-ORD
18h 27m2 stops
Multiple Airlines Logo
10:20 pm - 8:50 amORD-PTY
9h 30m1 stop
$404Multiple Airlines
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Thu, Oct 30 - Thu, Nov 6
Copa Airlines Logo
7:20 pm - 1:05 amPTY-ORD
5h 45mnonstop
Copa Airlines Logo
2:07 pm - 8:35 pmORD-PTY
5h 28mnonstop
$418Copa Airlines
Find Deal
Sat, Nov 1 - Thu, Nov 6
Multiple Airlines Logo
3:35 pm - 10:22 amPTY-ORD
18h 47m2 stops
Multiple Airlines Logo
8:50 pm - 1:00 amORD-PTY
27h 10m3 stops
$420Multiple Airlines
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Sat, Nov 1 - Wed, Nov 5
United Airlines Logo
10:00 am - 10:37 pmPTY-ORD
12h 37m1 stop
United Airlines Logo
7:10 am - 7:38 pmORD-PTY
11h 28m1 stop
$423United Airlines
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Fri, Oct 24 - Tue, Nov 11
Avianca Logo
2:55 am - 9:20 pmPTY-ORD
18h 25m1 stop
Avianca Logo
10:20 pm - 4:55 pmORD-PTY
17h 35m1 stop
$427Avianca
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Wed, Oct 29 - Thu, Nov 6
Avianca Logo
2:55 am - 8:20 pmPTY-ORD
18h 25m1 stop
Avianca Logo
10:20 pm - 4:55 pmORD-PTY
17h 35m1 stop
$431Avianca
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Tue, Feb 17 - Thu, Feb 26
American Airlines Logo
2:43 pm - 9:05 amPTY-ORD
19h 22m1 stop
American Airlines Logo
5:00 am - 3:37 pmORD-PTY
9h 37m1 stop
$435American Airlines
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Fri, Nov 21 - Sun, Dec 7
American Airlines Logo
3:31 pm - 8:40 amPTY-ORD
17h 09m1 stop
American Airlines Logo
5:00 am - 2:31 pmORD-PTY
9h 31m1 stop
$436American Airlines
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Mon, Sep 29 - Sun, Oct 5
United Airlines Logo
3:41 pm - 12:15 amPTY-ORD
8h 34m1 stop
United Airlines Logo
9:08 pm - 2:45 pmORD-PTY
16h 37m1 stop
$504United Airlines
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Fri, Oct 31 - Wed, Nov 5
Delta Logo
3:37 pm - 12:02 amPTY-ORD
9h 25m1 stop
Delta Logo
5:32 am - 2:12 pmORD-PTY
7h 40m1 stop
$506Delta
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Sun, Nov 23 - Sun, Nov 30

United Airlines flights from Panama City to Chicago O'Hare Intl Airport

Our best United Airlines deals on Panama City to Chicago O'Hare Intl Airport flight tickets
United Airlines
Oct 1
PTY3:30 pmPanama City Tocumen Intl
18h 40m
1 stop
ORD10:10 amChicago O'Hare Intl
Oct 15
ORD6:00 amChicago O'Hare Intl
8h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
$423
Find similar
United Airlines
Oct 31
PTY3:41 pmPanama City Tocumen Intl
8h 34m
1 stop
ORD12:15 amChicago O'Hare Intl
Nov 5
ORD9:08 pmChicago O'Hare Intl
16h 37m
1 stop
PTY2:45 pmPanama City Tocumen Intl
$504
Find similar
United Airlines
Oct 27
PTY3:41 pmPanama City Tocumen Intl
17h 30m
1 stop
ORD9:11 amChicago O'Hare Intl
Oct 31
ORD5:50 pmChicago O'Hare Intl
19h 55m
1 stop
PTY1:45 pmPanama City Tocumen Intl
$505
Find similar

American Airlines flights from Panama City to Chicago O'Hare Intl Airport

Our best American Airlines deals on Panama City to Chicago O'Hare Intl Airport flight tickets
American Airlines
Sep 29
PTY3:31 pmPanama City Tocumen Intl
25h 15m
1 stop
ORD4:46 pmChicago O'Hare Intl
Oct 5
ORD7:30 pmChicago O'Hare Intl
18h 33m
1 stop
PTY2:03 pmPanama City Tocumen Intl
$434
Find similar
American Airlines
Nov 21
PTY2:43 pmPanama City Tocumen Intl
19h 22m
1 stop
ORD9:05 amChicago O'Hare Intl
Dec 7
ORD5:00 amChicago O'Hare Intl
9h 37m
1 stop
PTY3:37 pmPanama City Tocumen Intl
$435
Find similar
American Airlines
Sep 29
PTY3:31 pmPanama City Tocumen Intl
17h 09m
1 stop
ORD8:40 amChicago O'Hare Intl
Oct 5
ORD5:00 amChicago O'Hare Intl
9h 31m
1 stop
PTY2:31 pmPanama City Tocumen Intl
$436
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama City to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 10/30

2:55 pm-9:22 am

2 stops18h 27m

Chicago O'Hare Intl

Thu 11/6

10:20 pm-8:50 am

1 stop9h 30m

$404

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 11/1

7:20 pm-1:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Thu 11/6

2:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 11/1

3:35 pm-10:22 am

2 stops18h 47m

Chicago O'Hare Intl

Wed 11/5

8:50 pm-1:00 am

3 stops27h 10m

$420

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 10/24

10:00 am-10:37 pm

1 stop12h 37m

Chicago O'Hare Intl

Tue 11/11

7:10 am-7:38 pm

1 stop11h 28m

$423

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 10/29

2:55 am-9:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Thu 11/6

10:20 pm-4:55 pm

1 stop17h 35m

$427

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 2/17

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Thu 2/26

10:20 pm-4:55 pm

1 stop17h 35m

$431

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 11/21

2:43 pm-9:05 am

1 stop19h 22m

Chicago O'Hare Intl

Sun 12/7

5:00 am-3:37 pm

1 stop9h 37m

$435

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 9/29

3:31 pm-8:40 am

1 stop17h 09m

Chicago O'Hare Intl

Sun 10/5

5:00 am-2:31 pm

1 stop9h 31m

$436

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 10/31

3:41 pm-12:15 am

1 stop8h 34m

Chicago O'Hare Intl

Wed 11/5

9:08 pm-2:45 pm

1 stop16h 37m

$504

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 11/23

3:37 pm-12:02 am

1 stop9h 25m

Chicago O'Hare Intl

Sun 11/30

5:32 am-2:12 pm

1 stop7h 40m

$506

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Chicago O'Hare Intl Airport?

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of October is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Panama City averaging around $479.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Wednesday when prices can be found for as low as $533. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Panama City because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,088.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Panama City in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $552 when looking at flights departing in the afternoon. Try not to purchase tickets in the evening because they tend to be around $887. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama City Tocumen Intl to Chicago O'Hare Intl flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $576 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Panama City for as low as $506 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Chicago O'Hare Intl flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Panama City to Chicago O'Hare Intl Airport.

How have Panama City to Chicago O'Hare Intl Airport flight prices changed over time?

When to book flights from Panama City to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Chicago O'Hare Intl Airport (PTY to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago O'Hare Intl Airport

Best Price Found

$722

Fastest flight time

5h 36m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from Panama City in the past 72 hours is $722. The best round-trip flight deal from Panama City to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $433.
The fastest flight from Panama City to Chicago O'Hare Intl Airport takes 5h 36m
Direct flights go from Panama City to Chicago O'Hare Intl Airport every day.
Search flight deals

  • How far is Panama City Tocumen Intl to Chicago O'Hare Intl by plane?

    Panama City Tocumen Intl and Chicago O'Hare Intl are 2334.5 mi apart from one another. By plane, this route typically takes 5h 45m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents you'll need for your trip to Chicago O'Hare Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago O'Hare Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Chicago O'Hare Intl Airport?

  • What is the most popular airline from Panama City to Chicago O'Hare Intl Airport?

Best airlines flying from Panama City to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Panama City to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $415Free CancellationRating
7.6
1,533 reviews
Search Copa Airlines flights
DeltaPriceFrom $598Free CancellationRating
7.9
7,961 reviews
Search Delta flights

  • Copa Airlines Flights From Panama City to Chicago O'Hare Intl Airport

    Copa Airlines flies from Panama City to Chicago O'Hare Intl Airport around 10 times per week, with 1,533 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Panama City to Chicago O'Hare Intl Airport in the last 72 hours was $415 (round-trip), much lower than the average airfare cost of $558 for Copa Airlines flights on this route.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
South Haven
Rockford
Schaumburg
Merrillville
Gurnee
Naperville
Rosemont
Kenosha
New Buffalo
Joliet
Oak Brook
Racine
Hammond
Orland Park
Tinley Park
Elgin
Aurora
Janesville
Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Chicago?

Once you have performed a search for Panama City to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Chicago, momondo offers a useful price alert feature which will track prices for flights to Chicago from Panama City and alert you when they change.

An easier way to manage your Chicago O'Hare Intl Airport trip

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