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Cheap flights from Panama City to Chicago from $270

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 11/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Multiple Airlines Logo
9:25 am - 11:58 pmPTY-ORD
15h 33m1 stop
Multiple Airlines Logo
11:40 am - 8:50 amORD-PTY
20h 10m2 stops
$413Multiple Airlines
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lun., nov. 24 - lun., dic. 1
Multiple Airlines Logo
9:25 am - 11:58 pmPTY-ORD
15h 33m1 stop
Multiple Airlines Logo
11:40 am - 8:50 amORD-PTY
20h 10m2 stops
$436Multiple Airlines
Find Deal
lun., nov. 24 - jue., nov. 27
Avianca Logo
2:55 am - 8:20 pmPTY-ORD
18h 25m1 stop
Avianca Logo
10:20 pm - 4:55 pmORD-PTY
17h 35m1 stop
$527Avianca
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mar., nov. 4 - dom., nov. 9
Avianca Logo
9:45 am - 8:20 pmPTY-ORD
11h 35m1 stop
Avianca Logo
10:20 pm - 2:00 pmORD-PTY
14h 40m1 stop
$546Avianca
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lun., nov. 3 - mié., nov. 19
Copa Airlines Logo
7:20 pm - 12:04 amPTY-ORD
5h 44mnonstop
Copa Airlines Logo
2:22 pm - 8:35 pmORD-PTY
5h 13mnonstop
$580Copa Airlines
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sáb., feb. 14 - dom., feb. 22
Copa Airlines Logo
7:20 pm - 12:05 amPTY-ORD
5h 45mnonstop
Copa Airlines Logo
2:13 pm - 8:35 pmORD-PTY
5h 22mnonstop
$582Copa Airlines
Find Deal
sáb., dic. 20 - lun., ene. 5
United Airlines Logo
3:20 pm - 10:07 amPTY-ORD
18h 47m1 stop
United Airlines Logo
10:42 am - 6:37 pmORD-PTY
7h 55m1 stop
$585United Airlines
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jue., abr. 2 - dom., abr. 5
United Airlines Logo
4:41 pm - 12:14 amPTY-ORD
8h 33m1 stop
United Airlines Logo
9:05 am - 8:02 pmORD-PTY
9h 57m1 stop
$587United Airlines
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sáb., dic. 20 - lun., ene. 5
American Airlines Logo
4:40 pm - 11:59 pmPTY-ORD
8h 19m1 stop
American Airlines Logo
8:25 pm - 1:10 pmORD-PTY
15h 45m2 stops
$599American Airlines
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sáb., feb. 14 - sáb., feb. 21
American Airlines Logo
4:43 pm - 8:14 amPTY-ORD
16h 31m2 stops
American Airlines Logo
5:00 am - 2:20 pmORD-PTY
9h 20m1 stop
$600American Airlines
Find Deal
mar., dic. 16 - mar., mar. 31

Copa Airlines flights from Panama City to Chicago O'Hare Intl Airport

Our best Copa Airlines deals on Panama City to Chicago O'Hare Intl Airport flight tickets
Copa Airlines
Feb 14
PTY7:20 pmPanama City Tocumen Intl
5h 44m
ORD12:04 amChicago O'Hare Intl
Feb 22
ORD2:22 pmChicago O'Hare Intl
5h 13m
PTY8:35 pmPanama City Tocumen Intl
$580
Find similar
Copa Airlines
Dec 20
PTY7:20 pmPanama City Tocumen Intl
5h 45m
ORD12:05 amChicago O'Hare Intl
Jan 5
ORD2:13 pmChicago O'Hare Intl
5h 22m
PTY8:35 pmPanama City Tocumen Intl
$582
Find similar
Copa Airlines
Dec 23
PTY7:20 pmPanama City Tocumen Intl
5h 45m
ORD12:05 amChicago O'Hare Intl
Jan 2
ORD7:35 amChicago O'Hare Intl
5h 25m
PTY2:00 pmPanama City Tocumen Intl
$598
Find similar

American Airlines flights from Panama City to Chicago O'Hare Intl Airport

Our best American Airlines deals on Panama City to Chicago O'Hare Intl Airport flight tickets
American Airlines
Feb 14
PTY4:40 pmPanama City Tocumen Intl
8h 19m
1 stop
ORD11:59 pmChicago O'Hare Intl
Feb 21
ORD8:25 pmChicago O'Hare Intl
15h 45m
2 stops
PTY1:10 pmPanama City Tocumen Intl
$599
Find similar
American Airlines
Dec 16
PTY4:43 pmPanama City Tocumen Intl
16h 31m
2 stops
ORD8:14 amChicago O'Hare Intl
Mar 31
ORD5:00 amChicago O'Hare Intl
9h 20m
1 stop
PTY2:20 pmPanama City Tocumen Intl
$600
Find similar
American Airlines
Dec 13
PTY4:43 pmPanama City Tocumen Intl
15h 57m
2 stops
ORD7:40 amChicago O'Hare Intl
Jan 4
ORD7:35 pmChicago O'Hare Intl
17h 18m
1 stop
PTY1:53 pmPanama City Tocumen Intl
$601
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 23, 2025.
Use the filters below to find and compare flights from Panama City to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

lun. 11/24

9:25 am-11:58 pm

1 stop15h 33m

Chicago O'Hare Intl

lun. 12/1

11:40 am-8:50 am

2 stops20h 10m

$413

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

lun. 11/24

9:25 am-11:58 pm

1 stop15h 33m

Chicago O'Hare Intl

jue. 11/27

11:40 am-8:50 am

2 stops20h 10m

$436

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

mar. 11/4

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

dom. 11/9

10:20 pm-4:55 pm

1 stop17h 35m

$527

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

lun. 11/3

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

mié. 11/19

10:20 pm-2:00 pm

1 stop14h 40m

$546

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

sáb. 2/14

7:20 pm-12:04 am

Nonstop5h 44m

Chicago O'Hare Intl

dom. 2/22

2:22 pm-8:35 pm

Nonstop5h 13m

$580

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

sáb. 12/20

7:20 pm-12:05 am

Nonstop5h 45m

Chicago O'Hare Intl

lun. 1/5

2:13 pm-8:35 pm

Nonstop5h 22m

$582

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

jue. 4/2

3:20 pm-10:07 am

1 stop18h 47m

Chicago O'Hare Intl

dom. 4/5

10:42 am-6:37 pm

1 stop7h 55m

$585

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

sáb. 12/20

4:41 pm-12:14 am

1 stop8h 33m

Chicago O'Hare Intl

lun. 1/5

9:05 am-8:02 pm

1 stop9h 57m

$587

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

sáb. 2/14

4:40 pm-11:59 pm

1 stop8h 19m

Chicago O'Hare Intl

sáb. 2/21

8:25 pm-1:10 pm

2 stops15h 45m

$599

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

mar. 12/16

4:43 pm-8:14 am

2 stops16h 31m

Chicago O'Hare Intl

mar. 3/31

5:00 am-2:20 pm

1 stop9h 20m

$600

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Chicago O'Hare Intl Airport?

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of March is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Panama City averaging around $479.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Wednesday when prices can be found for as low as $494. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Panama City because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $799.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Panama City in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $557 when looking at flights departing in the afternoon. Try not to purchase tickets in the morning because they tend to be around $642. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama City Tocumen Intl to Chicago O'Hare Intl flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $572 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Panama City for as low as $500 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Chicago O'Hare Intl flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Panama City to Chicago O'Hare Intl Airport.

How have Panama City to Chicago O'Hare Intl Airport flight prices changed over time?

When to book flights from Panama City to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Chicago O'Hare Intl Airport (PTY to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago O'Hare Intl Airport

Best Price Found

$574

Fastest flight time

5h 36m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from Panama City in the past 72 hours is $574. The best round-trip flight deal from Panama City to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $418.
The fastest flight from Panama City to Chicago O'Hare Intl Airport takes 5h 36m
Direct flights go from Panama City to Chicago O'Hare Intl Airport every day.
Search flight deals

  • How far is Panama City Tocumen Intl to Chicago O'Hare Intl by plane?

    Panama City Tocumen Intl and Chicago O'Hare Intl are 2334.5 mi apart from one another. By plane, this route typically takes 5h 36m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents you'll need for your trip to Chicago O'Hare Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago O'Hare Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Chicago O'Hare Intl Airport?

  • What is the most popular airline from Panama City to Chicago O'Hare Intl Airport?

Best airlines flying from Panama City to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Panama City to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $415Free CancellationRating
7.6
1,560 reviews
Search Copa Airlines flights

  • Copa Airlines Flights From Panama City to Chicago O'Hare Intl Airport

    Copa Airlines flies from Panama City to Chicago O'Hare Intl Airport around 9 times per week, with 1,560 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Panama City to Chicago O'Hare Intl Airport in the last 72 hours was $415 (round-trip), much lower than the average airfare cost of $581 for Copa Airlines flights on this route.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
South Haven
Schaumburg
Rockford
Merrillville
Gurnee
Naperville
Rosemont
Kenosha
New Buffalo
Joliet
Oak Brook
Orland Park
Racine
Hammond
Tinley Park
Janesville
Elgin
Aurora
Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Chicago?

Once you have performed a search for Panama City to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Chicago, momondo offers a useful price alert feature which will track prices for flights to Chicago from Panama City and alert you when they change.

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