Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City to Chicago from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 12/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
5:37 pm - 10:21 pmPTY-ORD
5h 44mnonstop
Copa Airlines Logo
2:13 pm - 8:35 pmORD-PTY
5h 22mnonstop
$418Copa Airlines
Find Deal
Sat, Dec 20 - Mon, Jan 5
Delta Logo
8:00 am - 4:19 pmPTY-ORD
9h 19m1 stop
Delta Logo
5:30 am - 8:00 pmORD-PTY
13h 30m1 stop
$424Delta
Find Deal
Tue, Dec 23 - Tue, Dec 30
American Airlines Logo
4:43 pm - 8:49 amPTY-ORD
17h 06m1 stop
American Airlines Logo
7:07 pm - 1:47 pmORD-PTY
17h 40m1 stop
$433American Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
Copa Airlines Logo
7:56 am - 12:52 pmPTY-ORD
5h 56mnonstop
Copa Airlines Logo
2:13 pm - 8:35 pmORD-PTY
5h 22mnonstop
$434Copa Airlines
Find Deal
Sun, Dec 28 - Fri, Jan 9
American Airlines Logo
4:43 pm - 7:19 amPTY-ORD
15h 36m2 stops
American Airlines Logo
7:07 pm - 1:47 pmORD-PTY
17h 40m1 stop
$437American Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
American Airlines Logo
2:43 pm - 7:04 amPTY-ORD
17h 21m2 stops
American Airlines Logo
10:05 pm - 1:47 pmORD-PTY
14h 42m2 stops
$439American Airlines
Find Deal
Fri, Nov 21 - Sun, Dec 7
Multiple Airlines Logo
11:25 am - 12:18 amPTY-ORD
13h 53m2 stops
Multiple Airlines Logo
10:20 pm - 4:55 pmORD-PTY
17h 35m1 stop
$495Multiple Airlines
Find Deal
Wed, Jan 21 - Sat, Jan 31
Multiple Airlines Logo
2:46 pm - 12:40 pmPTY-ORD
22h 54m1 stop
Multiple Airlines Logo
10:20 pm - 8:50 amORD-PTY
9h 30m1 stop
$505Multiple Airlines
Find Deal
Tue, Jan 20 - Fri, Feb 20
Avianca Logo
2:55 am - 8:20 pmPTY-ORD
18h 25m1 stop
Avianca Logo
10:20 pm - 8:50 amORD-PTY
9h 30m1 stop
$516Avianca
Find Deal
Thu, Jan 22 - Mon, Feb 2
Avianca Logo
2:55 am - 8:20 pmPTY-ORD
18h 25m1 stop
Avianca Logo
10:20 pm - 4:55 pmORD-PTY
17h 35m1 stop
$520Avianca
Find Deal
Wed, Nov 26 - Mon, Dec 1

American Airlines flights from Panama City to Chicago O'Hare Intl Airport

Our best American Airlines deals on Panama City to Chicago O'Hare Intl Airport flight tickets
American Airlines
Dec 3
PTY4:43 pmPanama City Tocumen Intl
17h 06m
1 stop
ORD8:49 amChicago O'Hare Intl
Dec 10
ORD7:07 pmChicago O'Hare Intl
17h 40m
1 stop
PTY1:47 pmPanama City Tocumen Intl
$433
Find similar
American Airlines
Dec 3
PTY4:43 pmPanama City Tocumen Intl
15h 36m
2 stops
ORD7:19 amChicago O'Hare Intl
Dec 10
ORD7:07 pmChicago O'Hare Intl
17h 40m
1 stop
PTY1:47 pmPanama City Tocumen Intl
$437
Find similar
American Airlines
Nov 21
PTY2:43 pmPanama City Tocumen Intl
17h 21m
2 stops
ORD7:04 amChicago O'Hare Intl
Dec 7
ORD10:05 pmChicago O'Hare Intl
14h 42m
2 stops
PTY1:47 pmPanama City Tocumen Intl
$439
Find similar

Copa Airlines flights from Panama City to Chicago O'Hare Intl Airport

Our best Copa Airlines deals on Panama City to Chicago O'Hare Intl Airport flight tickets
Copa Airlines
Nov 20
PTY7:20 pmPanama City Tocumen Intl
5h 45m
ORD12:05 amChicago O'Hare Intl
Nov 24
ORD6:56 amChicago O'Hare Intl
5h 26m
PTY1:22 pmPanama City Tocumen Intl
$418
Find similar
Copa Airlines
Dec 28
PTY7:56 amPanama City Tocumen Intl
5h 56m
ORD12:52 pmChicago O'Hare Intl
Jan 9
ORD2:13 pmChicago O'Hare Intl
5h 22m
PTY8:35 pmPanama City Tocumen Intl
$434
Find similar
Copa Airlines
Feb 1
PTY7:55 amPanama City Tocumen Intl
5h 36m
ORD12:31 pmChicago O'Hare Intl
Feb 6
ORD7:34 amChicago O'Hare Intl
5h 26m
PTY2:00 pmPanama City Tocumen Intl
$450
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Panama City to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 12/20

5:37 pm-10:21 pm

Nonstop5h 44m

Chicago O'Hare Intl

Mon 1/5

2:13 pm-8:35 pm

Nonstop5h 22m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 12/23

8:00 am-4:19 pm

1 stop9h 19m

Chicago O'Hare Intl

Tue 12/30

5:30 am-8:00 pm

1 stop13h 30m

$424

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 12/3

4:43 pm-8:49 am

1 stop17h 06m

Chicago O'Hare Intl

Wed 12/10

7:07 pm-1:47 pm

1 stop17h 40m

$433

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 12/28

7:56 am-12:52 pm

Nonstop5h 56m

Chicago O'Hare Intl

Fri 1/9

2:13 pm-8:35 pm

Nonstop5h 22m

$434

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 12/3

4:43 pm-7:19 am

2 stops15h 36m

Chicago O'Hare Intl

Wed 12/10

7:07 pm-1:47 pm

1 stop17h 40m

$437

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 11/21

2:43 pm-7:04 am

2 stops17h 21m

Chicago O'Hare Intl

Sun 12/7

10:05 pm-1:47 pm

2 stops14h 42m

$439

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 1/21

11:25 am-12:18 am

2 stops13h 53m

Chicago O'Hare Intl

Sat 1/31

10:20 pm-4:55 pm

1 stop17h 35m

$495

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 1/20

2:46 pm-12:40 pm

1 stop22h 54m

Chicago O'Hare Intl

Fri 2/20

10:20 pm-8:50 am

1 stop9h 30m

$505

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 1/22

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Mon 2/2

10:20 pm-8:50 am

1 stop9h 30m

$516

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 11/26

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Mon 12/1

10:20 pm-4:55 pm

1 stop17h 35m

$520

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of March is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Panama City averaging around $479.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Wednesday when prices can be found for as low as $494. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Panama City because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $799.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Panama City in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $562 when looking at flights departing in the afternoon. Try not to purchase tickets in the morning because they tend to be around $672. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama City Tocumen Intl to Chicago O'Hare Intl flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $571 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Panama City for as low as $500 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Chicago O'Hare Intl flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Panama City to Chicago O'Hare Intl Airport.

How have Panama City to Chicago O'Hare Intl Airport flight prices changed over time?

When to book flights from Panama City to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Chicago O'Hare Intl Airport (PTY to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago O'Hare Intl Airport

Best Price Found

$574

Fastest flight time

5h 36m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from Panama City in the past 72 hours is $574. The best round-trip flight deal from Panama City to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $533.
The fastest flight from Panama City to Chicago O'Hare Intl Airport takes 5h 36m
Direct flights go from Panama City to Chicago O'Hare Intl Airport every day.
Search flight deals

  • How far is Panama City Tocumen Intl to Chicago O'Hare Intl by plane?

    Panama City Tocumen Intl and Chicago O'Hare Intl are 2334.5 mi apart from one another. By plane, this route typically takes 5h 36m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents you'll need for your trip to Chicago O'Hare Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago O'Hare Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Chicago O'Hare Intl Airport?

  • What is the most popular airline from Panama City to Chicago O'Hare Intl Airport?

Best airlines flying from Panama City to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Panama City to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $415Free CancellationRating
7.6
1,563 reviews
Search Copa Airlines flights

  • Copa Airlines Flights From Panama City to Chicago O'Hare Intl Airport

    Copa Airlines flies from Panama City to Chicago O'Hare Intl Airport around 12 times per week, with 1,561 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Panama City to Chicago O'Hare Intl Airport in the last 72 hours was $415 (round-trip), much lower than the average airfare cost of $586 for Copa Airlines flights on this route.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
South Haven
Schaumburg
Rockford
Merrillville
Gurnee
Naperville
Rosemont
Kenosha
New Buffalo
Joliet
Oak Brook
Orland Park
Racine
Hammond
Tinley Park
Janesville
Aurora
Elgin
Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Chicago?

Once you have performed a search for Panama City to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Chicago, momondo offers a useful price alert feature which will track prices for flights to Chicago from Panama City and alert you when they change.

An easier way to manage your Chicago O'Hare Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 12/6
Sat 12/13
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chicago