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Cheap flights from Panama City to Chicago from $321

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 9/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama City to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
4:25 am - 9:20 pm
PTY
-
ORD
16h 55m
1 stop
Avianca Logo
11:20 pm - 9:15 am
ORD
-
PTY
9h 55m
1 stop
$687Avianca
Wed, Aug 19 - Sun, Aug 23
Avianca Logo
5:30 am - 3:55 pm
PTY
-
ORD
10h 25m
1 stop
Avianca Logo
11:20 pm - 9:15 am
ORD
-
PTY
9h 55m
1 stop
$688Avianca
Tue, Aug 25 - Sun, Aug 30
Avianca Logo
5:30 am - 3:55 pm
PTY
-
ORD
10h 25m
1 stop
Avianca Logo
5:15 pm - 1:55 am
ORD
-
PTY
8h 40m
1 stop
$690Avianca
Sat, Aug 22 - Sat, Aug 29
Avianca Logo
2:55 am - 8:20 pm
PTY
-
ORD
18h 25m
1 stop
Avianca Logo
10:20 pm - 2:00 pm
ORD
-
PTY
14h 40m
1 stop
$708Avianca
Sat, Oct 31 - Fri, Nov 6
Avianca Logo
10:10 am - 9:20 pm
PTY
-
ORD
11h 10m
1 stop
Avianca Logo
11:20 pm - 9:15 am
ORD
-
PTY
9h 55m
1 stop
$712Avianca
Wed, Jul 29 - Sun, Aug 2
Avianca Logo
4:25 am - 9:20 pm
PTY
-
ORD
16h 55m
1 stop
Avianca Logo
11:20 pm - 12:35 am
ORD
-
PTY
25h 15m
1 stop
$713Avianca
Sat, Jul 18 - Wed, Aug 26
Multiple Airlines Logo
9:33 pm - 1:36 pm
PTY
-
ORD
16h 03m
2 stops
Multiple Airlines Logo
7:35 am - 5:54 pm
ORD
-
PTY
10h 19m
1 stop
$719Multiple Airlines
Tue, Aug 25 - Sun, Aug 30
Multiple Airlines Logo
12:03 pm - 12:50 pm
PTY
-
ORD
24h 47m
1 stop
Multiple Airlines Logo
2:03 pm - 8:06 am
ORD
-
PTY
18h 03m
2 stops
$727Multiple Airlines
Mon, Aug 31 - Tue, Sep 15
Avianca Logo
10:10 am - 9:20 pm
PTY
-
ORD
11h 10m
1 stop
Avianca Logo
11:20 pm - 2:15 pm
ORD
-
PTY
14h 55m
1 stop
$729Avianca
Fri, Aug 14 - Wed, Aug 19
Multiple Airlines Logo
3:10 pm - 9:20 pm
PTY
-
ORD
30h 10m
1 stop
Multiple Airlines Logo
2:53 am - 9:15 am
ORD
-
PTY
30h 22m
3 stops
$733Multiple Airlines
Sat, Aug 22 - Fri, Aug 28

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Avianca flights from Panama City to Chicago O'Hare Intl Airport

Our best Avianca deals on Panama City to Chicago O'Hare Intl Airport flight tickets
Avianca
Jul 9
PTY10:10 amPanama City Tocumen Intl
11h 10m
1 stop
ORD9:20 pmChicago O'Hare Intl
Jul 15
ORD11:20 pmChicago O'Hare Intl
17h 40m
1 stop
PTY5:00 pmPanama City Tocumen Intl
$684
Avianca
Aug 19
PTY10:10 amPanama City Tocumen Intl
11h 10m
1 stop
ORD9:20 pmChicago O'Hare Intl
Aug 23
ORD11:20 pmChicago O'Hare Intl
14h 55m
1 stop
PTY2:15 pmPanama City Tocumen Intl
$687
Avianca
Aug 25
PTY5:30 amPanama City Tocumen Intl
10h 25m
1 stop
ORD3:55 pmChicago O'Hare Intl
Aug 30
ORD11:20 pmChicago O'Hare Intl
9h 55m
1 stop
PTY9:15 amPanama City Tocumen Intl
$688

American Airlines flights from Panama City to Chicago O'Hare Intl Airport

Our best American Airlines deals on Panama City to Chicago O'Hare Intl Airport flight tickets
American Airlines
Sep 14
PTY1:16 pmPanama City Tocumen Intl
19h 36m
2 stops
ORD8:52 amChicago O'Hare Intl
Sep 18
ORD8:55 pmChicago O'Hare Intl
15h 21m
2 stops
PTY12:16 pmPanama City Tocumen Intl
$777
American Airlines
Nov 1
PTY2:43 pmPanama City Tocumen Intl
17h 44m
2 stops
ORD7:27 amChicago O'Hare Intl
Nov 6
ORD8:58 pmChicago O'Hare Intl
15h 38m
2 stops
PTY1:36 pmPanama City Tocumen Intl
$781
American Airlines
Oct 3
PTY1:16 pmPanama City Tocumen Intl
18h 42m
2 stops
ORD7:58 amChicago O'Hare Intl
Oct 7
ORD5:28 pmChicago O'Hare Intl
19h 24m
1 stop
PTY12:52 pmPanama City Tocumen Intl
$790

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 7, 2026.
Use the filters below to find and compare flights from Panama City to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 8/19

4:25 am-9:20 pm

1 stop16h 55m

Chicago O'Hare Intl

Sun 8/23

11:20 pm-9:15 am

1 stop9h 55m

$687

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 8/25

5:30 am-3:55 pm

1 stop10h 25m

Chicago O'Hare Intl

Sun 8/30

11:20 pm-9:15 am

1 stop9h 55m

$688
Quickest round-trip

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 8/22

5:30 am-3:55 pm

1 stop10h 25m

Chicago O'Hare Intl

Sat 8/29

5:15 pm-1:55 am

1 stop8h 40m

$690

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 10/31

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Fri 11/6

10:20 pm-2:00 pm

1 stop14h 40m

$708

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 7/29

10:10 am-9:20 pm

1 stop11h 10m

Chicago O'Hare Intl

Sun 8/2

11:20 pm-9:15 am

1 stop9h 55m

$712

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 7/18

4:25 am-9:20 pm

1 stop16h 55m

Chicago O'Hare Intl

Wed 8/26

11:20 pm-12:35 am

1 stop25h 15m

$713

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 8/25

9:33 pm-1:36 pm

2 stops16h 03m

Chicago O'Hare Intl

Sun 8/30

7:35 am-5:54 pm

1 stop10h 19m

$719

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 8/31

12:03 pm-12:50 pm

1 stop24h 47m

Chicago O'Hare Intl

Tue 9/15

2:03 pm-8:06 am

2 stops18h 03m

$727

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 8/14

10:10 am-9:20 pm

1 stop11h 10m

Chicago O'Hare Intl

Wed 8/19

11:20 pm-2:15 pm

1 stop14h 55m

$729

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 8/22

3:10 pm-9:20 pm

1 stop30h 10m

Chicago O'Hare Intl

Fri 8/28

2:53 am-9:15 am

3 stops30h 22m

$733

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Chicago O'Hare Intl Airport?

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of September is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Panama City averaging around $543.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Saturday when prices can be found for as low as $533. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Panama City because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $887.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Panama City in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $496 when looking at flights departing in the afternoon. Try not to purchase tickets in the morning because they tend to be around $784. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama City Tocumen Intl to Chicago O'Hare Intl flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Chicago O'Hare Intl flight prices

How far in advance should I book a flight from Panama City to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $660 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Panama City for as low as $477 on momondo.

What cabin class options are available on Panama City to Chicago O'Hare Intl Airport flights?

There are 3 cabin classes available to choose from on Panama City to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Chicago O'Hare Intl Airport flights?

You could potentially save up to 50% on your flight if you consider stops on a Panama City to Chicago O'Hare Intl Airport flight.

How have Panama City to Chicago O'Hare Intl Airport flight prices changed over time?

When to book flights from Panama City to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Chicago O'Hare Intl Airport (PTY to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago O'Hare Intl Airport

Best Price Found

$698

Fastest flight time

5h 37m

Direct flights

Tue, Wed, Thu, Fri, Sat and Sun
The best one-way flight to Chicago O'Hare Intl Airport from Panama City in the past 72 hours is $698. The best round-trip flight deal from Panama City to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $827.
The fastest flight from Panama City to Chicago O'Hare Intl Airport takes 5h 37m
Direct flights go from Panama City to Chicago O'Hare Intl Airport on Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Copa Airlines.
Search flight deals

Frequently asked questions about flying from Panama City to Chicago O'Hare Intl Airport

  • How far is Panama City Tocumen Intl to Chicago O'Hare Intl by plane?

    Panama City Tocumen Intl and Chicago O'Hare Intl are 2334.5 mi apart from one another. By plane, this route typically takes 5h 37m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City Tocumen Intl Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents you'll need for your trip to Chicago O'Hare Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago O'Hare Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Chicago O'Hare Intl Airport?

  • What is the most popular airline from Panama City to Chicago O'Hare Intl Airport?

Best airlines flying from Panama City to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Panama City to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $417Free CancellationRating
7.6
1,568 reviews
Search Copa Airlines flights

  • Copa Airlines Flights From Panama City to Chicago O'Hare Intl Airport

    Copa Airlines flies from Panama City to Chicago O'Hare Intl Airport around 16 times per week, with 1,568 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Panama City to Chicago O'Hare Intl Airport in the last 72 hours was $417 (round-trip), much lower than the average airfare cost of $729 for Copa Airlines flights on this route.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
Schaumburg
South Haven
Rockford
Merrillville
Gurnee
Rosemont
Naperville
Orland Park
Oak Brook
New Buffalo
Joliet
Kenosha
Hammond
Aurora
Racine
Janesville
Elgin
Evanston
South Holland

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Chicago?

Once you have performed a search for Panama City to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Chicago, momondo offers a useful price alert feature which will track prices for flights to Chicago from Panama City and alert you when they change.

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