What is the cheapest airline that flies from Panama to Indiana?

Avianca, United Airlines, and Delta are the most popular carriers operating from Panama to Indiana

What airlines fly to Indiana?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Indiana from Panama according to our data. United Airlines is the first choice among our users, with 58% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 3 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

How many flights depart from Panama to Indiana on average per week?

The number of flights available between Panama and Indiana is 28 per week as of September 2025. The most frequent departure day is Mon, with 18% of weekly flights leaving on this day.

When did momondo last update prices for flights from Panama to Indiana?

Prices for flights from Panama to Indiana refresh daily.

How many operators does momondo search for flights from Panama to Indiana?

As of September 2025, there are 4 operators available to choose from for flights from Panama to Indiana.

How old do you have to be to fly from Panama to Indiana?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Indiana.

What documentation or ID do you need to fly to Indiana?

The travel and health documents required for your trip to Indiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$157 Cheap Flights from Panama to Indiana in 2025/26

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Find the cheapest flights from Panama to Indiana

Round-trip

One-way

Last minute

Direct

Recent round-trip flight deals from Panama to Indiana

2:55 am - 8:20 pmPTY-ORD

18h 25m1 stop

11:20 pm - 2:00 pmORD-PTY

14h 40m1 stop

$359Avianca

Find Deal

Wed, Mar 4 - Fri, Mar 20

2:55 am - 9:20 pmPTY-ORD

18h 25m1 stop

11:20 pm - 8:50 amORD-PTY

9h 30m1 stop

$365Avianca

Find Deal

Sun, Oct 26 - Fri, Oct 31

7:20 pm - 12:05 amPTY-ORD

5h 45mnonstop

2:13 pm - 8:35 pmORD-PTY

5h 22mnonstop

$418Copa Airlines

Find Deal

Sun, Dec 28 - Fri, Jan 9

8:00 am - 4:15 pmPTY-MDW

9h 15m1 stop

9:54 am - 8:00 pmMDW-PTY

9h 06m1 stop

$423Delta

Find Deal

Tue, Dec 23 - Fri, Jan 2

8:00 am - 4:24 pmPTY-ORD

9h 24m1 stop

6:45 am - 8:00 pmORD-PTY

12h 15m1 stop

$423Delta

Find Deal

Tue, Dec 23 - Sun, Jan 4

11:35 am - 12:14 amPTY-ORD

13h 39m1 stop

7:35 am - 5:07 pmORD-PTY

8h 32m1 stop

$432United Airlines

Find Deal

Sun, Dec 28 - Fri, Jan 9

2:43 pm - 9:05 amPTY-ORD

19h 22m1 stop

7:00 am - 3:37 pmORD-PTY

7h 37m1 stop

$433American Airlines

Find Deal

Fri, Nov 21 - Sun, Dec 7

7:50 am - 12:46 pmPTY-ORD

5h 56mnonstop

2:07 pm - 8:35 pmORD-PTY

5h 28mnonstop

$434Copa Airlines

Find Deal

Fri, Nov 21 - Sun, Dec 7

2:43 pm - 7:21 amPTY-ORD

17h 38m2 stops

5:00 am - 3:37 pmORD-PTY

9h 37m2 stops

$436American Airlines

Find Deal

Fri, Nov 21 - Sun, Dec 7

4:41 pm - 12:15 amPTY-ORD

8h 34m1 stop

7:10 am - 7:38 pmORD-PTY

11h 28m1 stop

$439United Airlines

Find Deal

Mon, Nov 3 - Wed, Nov 19

Avianca flights from Panama to Indiana

Our best Avianca deals on Panama to Indiana flight tickets

Avianca

Mar 4

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD8:20 pmChicago O'Hare Intl

Mar 20

ORD11:20 pmChicago O'Hare Intl

14h 40m

1 stop

PTY2:00 pmPanama City Tocumen Intl

$359

Find similar

Avianca

Oct 26

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD9:20 pmChicago O'Hare Intl

Oct 31

ORD11:20 pmChicago O'Hare Intl

9h 30m

1 stop

PTY8:50 amPanama City Tocumen Intl

$365

Find similar

Avianca

Nov 21

PTY9:45 amPanama City Tocumen Intl

11h 35m

1 stop

ORD8:20 pmChicago O'Hare Intl

Dec 7

ORD10:20 pmChicago O'Hare Intl

14h 40m

1 stop

PTY2:00 pmPanama City Tocumen Intl

$417

Find similar

Copa Airlines flights from Panama to Indiana

Our best Copa Airlines deals on Panama to Indiana flight tickets

Copa Airlines

Dec 28

PTY7:20 pmPanama City Tocumen Intl

5h 45m

ORD12:05 amChicago O'Hare Intl

Jan 9

ORD2:13 pmChicago O'Hare Intl

5h 22m

PTY8:35 pmPanama City Tocumen Intl

$418

Find similar

Copa Airlines

Nov 21

PTY7:50 amPanama City Tocumen Intl

5h 56m

ORD12:46 pmChicago O'Hare Intl

Dec 7

ORD2:07 pmChicago O'Hare Intl

5h 28m

PTY8:35 pmPanama City Tocumen Intl

$434

Find similar

Copa Airlines

Feb 1

PTY7:55 amPanama City Tocumen Intl

5h 36m

ORD12:31 pmChicago O'Hare Intl

Feb 6

ORD7:34 amChicago O'Hare Intl

5h 26m

PTY2:00 pmPanama City Tocumen Intl

$450

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 3/4

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Fri 3/20

11:20 pm-2:00 pm

1 stop14h 40m

$359

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 10/26

2:55 am-9:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Fri 10/31

11:20 pm-8:50 am

1 stop9h 30m

$365

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 12/28

7:20 pm-12:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Fri 1/9

2:13 pm-8:35 pm

Nonstop5h 22m

$418

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 12/23

8:00 am-4:15 pm

1 stop9h 15m

Chicago Midway

Fri 1/2

9:54 am-8:00 pm

1 stop9h 06m

$423

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 12/23

8:00 am-4:24 pm

1 stop9h 24m

Chicago O'Hare Intl

Sun 1/4

6:45 am-8:00 pm

1 stop12h 15m

$423

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 12/28

11:35 am-12:14 am

1 stop13h 39m

Chicago O'Hare Intl

Fri 1/9

7:35 am-5:07 pm

1 stop8h 32m

$432

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 11/21

2:43 pm-9:05 am

1 stop19h 22m

Chicago O'Hare Intl

Sun 12/7

7:00 am-3:37 pm

1 stop7h 37m

$433

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 11/21

7:50 am-12:46 pm

Nonstop5h 56m

Chicago O'Hare Intl

Sun 12/7

2:07 pm-8:35 pm

Nonstop5h 28m

$434

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 11/21

2:43 pm-7:21 am

2 stops17h 38m

Chicago O'Hare Intl

Sun 12/7

5:00 am-3:37 pm

2 stops9h 37m

$436

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 11/3

4:41 pm-12:15 am

1 stop8h 34m

Chicago O'Hare Intl

Wed 11/19

7:10 am-7:38 pm

1 stop11h 28m

$439

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Indiana?

The cheapest month to fly to Indiana from Panama is in December. Flight prices, which tend to average around $526, are often lower during this time because this is during the off-season. The month of March is another great option to travel to Indiana, with average flight prices from Panama averaging around $535.

What is the cheapest day to depart on your flight to Indiana?

Our data shows that Friday is the least expensive day to fly to Indiana. Tickets to fly out on this day can be as low as $489. On the other hand, Monday is the most expensive day to depart from Panama because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $593.

What is the cheapest time of day to depart on your flight to Indiana?

Our data shows that the cheapest Panama to Indiana flights are usually those with departure times at noon. Our users have found flights to Indiana at noon for as low as $507. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $617 on average. Flights to Indiana from Panama in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Panama to Indiana flights?

You could potentially save up to 4% on your flight if you consider stops on a Panama to Indiana flight.

Cheap Panama to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Indiana

Fastest flight time	5h 36m
Direct flights	Every day
Airports in Indiana	1 airport

The fastest flight from Panama to Indiana takes 5h 36m

Direct flights go from Panama to Indiana every day.

There is 1 airport near Indiana: Chicago O'Hare Intl (ORD)

Search flight deals

When did momondo last update prices for flights from Panama to Indiana?
Prices for flights from Panama to Indiana refresh daily.
How many operators does momondo search for flights from Panama to Indiana?
As of September 2025, there are 4 operators available to choose from for flights from Panama to Indiana.
How old do you have to be to fly from Panama to Indiana?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Indiana.
What documentation or ID do you need to fly to Indiana?
The travel and health documents required for your trip to Indiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Panama to Indiana

Compare and see reviews for airlines that fly from Panama to Indiana with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $312	Free Cancellation	Rating 7.9 7,973 reviews	Search Delta flights
United Airlines	PriceFrom $481	Free Cancellation	Rating 7.4 8,928 reviews	Search United Airlines flights
American Airlines	PriceFrom $496	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Indiana?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Indiana from Panama.

Can I find flights from Panama to Indiana with flexible booking policies on momondo?

All flight searches from Panama to Indiana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama to Indiana?

momondo provides multiple filters to help you find the best flight to Indiana from Panama. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama to Indiana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Indiana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.