Cheap flights from Panama City to Massachusetts from $388

In general, March is the cheapest month to fly from Panama City to Massachusetts. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $620. If you aren’t able to travel to Massachusetts during the month of March, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $632.

According to our data, Saturday is the cheapest day to fly to Massachusetts from Panama City. The lowest ticket price found for a Saturday departure recently was $713. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Tuesday is the most expensive day to depart from Panama City because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $847.

Our data shows that the cheapest Panama City to Massachusetts flights are usually those with departure times in the afternoon. Our users have found flights to Massachusetts in the afternoon for as low as $798. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $804 on average. Flights to Massachusetts from Panama City in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Panama City Tocumen Intl to Boston Logan Intl for the best Panama City Tocumen Intl - Massachusetts flight prices

You are more likely to see cheaper flights to Massachusetts from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Massachusetts for around $712 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Massachusetts from Panama City for as low as $477 on momondo.

There are 2 cabin classes available to choose from on Panama City to Massachusetts flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

American Airlines is the most popular carrier operating from Panama City Tocumen Intl to Massachusetts

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Massachusetts from Panama City according to our data. Copa Airlines is the first choice among our users, with 71% of people opting to fly with this airline when traveling to Massachusetts. Keep in mind that there are 3 different airlines that fly to Massachusetts on a routine basis, so you have a few additional options to choose from.

The number of flights available between Panama City and Massachusetts is 2 per day as of October 2026. The most frequent departure time is 4:00PM, with 100% of daily flights leaving in the afternoon.

As of October 2026, 15 flights take off from Panama City and land in Massachusetts each week. The most common flight departure day for this route is Wed, with 20% of weekly flights taking off on this day.