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Cheap flights from Panama City to Greenville from $602

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Greenville departing on 12/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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American Airlines Logo
2:43 pm - 9:39 amPTY-GSP
18h 56m2 stops
American Airlines Logo
6:01 am - 3:42 pmGSP-PTY
9h 41m2 stops
$602American Airlines
Find Deal
Mon, Dec 1 - Fri, Dec 12
American Airlines Logo
2:43 pm - 11:04 amPTY-GSP
20h 21m1 stop
American Airlines Logo
5:10 am - 1:47 pmGSP-PTY
8h 37m1 stop
$608American Airlines
Find Deal
Mon, Dec 1 - Fri, Dec 12
Multiple Airlines Logo
2:55 am - 7:23 pmPTY-GSP
16h 28m2 stops
Multiple Airlines Logo
3:00 pm - 8:19 pmGSP-PTY
29h 19m1 stop
$764Multiple Airlines
Find Deal
Sun, Nov 30 - Fri, Dec 12

American Airlines flights from Panama City to Greenville

Our best American Airlines deals on Panama City to Greenville flight tickets
American Airlines
Dec 1
PTY2:43 pmPanama City Tocumen Intl
18h 56m
2 stops
GSP9:39 amGreenville
Dec 12
GSP6:01 amGreenville
9h 41m
2 stops
PTY3:42 pmPanama City Tocumen Intl
$602
Find similar
American Airlines
Dec 1
PTY2:43 pmPanama City Tocumen Intl
20h 21m
1 stop
GSP11:04 amGreenville
Dec 12
GSP5:10 amGreenville
8h 37m
1 stop
PTY1:47 pmPanama City Tocumen Intl
$608
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Panama City to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Mon 12/1

2:43 pm-9:39 am

2 stops18h 56m

Greenville

Fri 12/12

6:01 am-3:42 pm

2 stops9h 41m

$602

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Mon 12/1

2:43 pm-11:04 am

1 stop20h 21m

Greenville

Fri 12/12

5:10 am-1:47 pm

1 stop8h 37m

$608

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Sun 11/30

2:55 am-7:23 pm

2 stops16h 28m

Greenville

Fri 12/12

3:00 pm-8:19 pm

1 stop29h 19m

$764

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Greenville from

How to get the cheapest flight ticket from Panama City to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Greenville?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Greenville from Panama City according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 3 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When to book flights from Panama City to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Greenville (PTY to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Greenville

Direct flights

None
There are no direct flights from Panama City to Greenville. There are no popular flight routes from Panama City to Greenville.
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  • How far is Panama City Tocumen Intl to Greenville by plane?

    The distance between Panama City Tocumen Intl and Greenville is about 1795.3 mi. By plane, this route typically takes 16h 28m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Greenville Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Greenville Airport refresh daily.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Greenville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Greenville. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Greenville.

I’m not ready to book a flight from Panama City to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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