Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City, Florida to St. Louis from $79

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to St. Louis departing on 9/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City, Florida to St. Louis

Cheap round-trip flights

Southwest Logo
3:15 pm - 5:05 pmECP-STL
1h 50mnonstop
Southwest Logo
3:30 pm - 5:15 pmSTL-ECP
1h 45mnonstop
$157Southwest
Find Deal
Sat, Aug 30 - Sat, Sep 6
Delta Logo
9:24 am - 2:37 pmECP-STL
5h 13m1 stop
Delta Logo
1:26 pm - 7:48 pmSTL-ECP
6h 22m1 stop
$177Delta
Find Deal
Wed, Aug 27 - Wed, Sep 3
American Airlines Logo
3:22 pm - 10:59 pmECP-STL
7h 37m1 stop
American Airlines Logo
6:02 am - 12:07 pmSTL-ECP
6h 05m1 stop
$187American Airlines
Find Deal
Fri, Aug 29 - Mon, Sep 1
American Airlines Logo
5:30 am - 12:11 pmECP-STL
6h 41m1 stop
American Airlines Logo
7:01 am - 5:36 pmSTL-ECP
10h 35m2 stops
$192American Airlines
Find Deal
Sat, Aug 30 - Sat, Sep 6
Southwest Logo
3:15 pm - 5:05 pmECP-STL
1h 50mnonstop
Southwest Logo
6:35 am - 11:25 amSTL-ECP
4h 50m1 stop
$197Southwest
Find Deal
Sat, Aug 30 - Sat, Sep 6
Southwest Logo
2:00 pm - 3:50 pmECP-STL
1h 50mnonstop
Southwest Logo
6:35 am - 3:20 pmSTL-ECP
8h 45m2 stops
$202Southwest
Find Deal
Fri, Oct 24 - Tue, Oct 28
Southwest Logo
1:35 pm - 3:25 pmECP-STL
1h 50mnonstop
Southwest Logo
8:10 am - 9:55 amSTL-ECP
1h 45mnonstop
$208Southwest
Find Deal
Fri, Sep 5 - Sun, Sep 7
Delta Logo
9:24 am - 4:06 pmECP-STL
6h 42m1 stop
Delta Logo
7:00 am - 10:34 amSTL-ECP
3h 34m1 stop
$248Delta
Find Deal
Fri, Aug 29 - Tue, Sep 9
United Airlines Logo
6:30 am - 2:26 pmECP-STL
7h 56m1 stop
United Airlines Logo
6:35 am - 4:20 pmSTL-ECP
9h 45m2 stops
$302United Airlines
Find Deal
Wed, Aug 27 - Sat, Sep 6
United Airlines Logo
5:06 pm - 10:08 pmECP-STL
5h 02m1 stop
United Airlines Logo
6:35 am - 1:03 pmSTL-ECP
6h 28m1 stop
$307United Airlines
Find Deal
Fri, Aug 29 - Sun, Sep 7

American Airlines flights from Panama City, Florida to St. Louis

Our best American Airlines deals on Panama City, Florida to St. Louis flight tickets
American Airlines
Aug 29
ECP3:22 pmPanama City NW Florida Beaches
7h 37m
1 stop
STL10:59 pmLambert-St Louis
Sep 1
STL6:02 amLambert-St Louis
6h 05m
1 stop
ECP12:07 pmPanama City NW Florida Beaches
$187
Find similar
American Airlines
Aug 30
ECP5:30 amPanama City NW Florida Beaches
6h 41m
1 stop
STL12:11 pmLambert-St Louis
Sep 6
STL7:01 amLambert-St Louis
10h 35m
2 stops
ECP5:36 pmPanama City NW Florida Beaches
$192
Find similar
American Airlines
Sep 5
ECP3:29 pmPanama City NW Florida Beaches
5h 41m
1 stop
STL9:10 pmLambert-St Louis
Sep 7
STL6:00 amLambert-St Louis
7h 59m
2 stops
ECP1:59 pmPanama City NW Florida Beaches
$252
Find similar

Southwest flights from Panama City, Florida to St. Louis

Our best Southwest deals on Panama City, Florida to St. Louis flight tickets
Southwest
Aug 30
ECP3:15 pmPanama City NW Florida Beaches
1h 50m
STL5:05 pmLambert-St Louis
Sep 6
STL3:30 pmLambert-St Louis
1h 45m
ECP5:15 pmPanama City NW Florida Beaches
$157
Find similar
Southwest
Aug 30
ECP3:15 pmPanama City NW Florida Beaches
1h 50m
STL5:05 pmLambert-St Louis
Sep 6
STL6:35 amLambert-St Louis
4h 50m
1 stop
ECP11:25 amPanama City NW Florida Beaches
$197
Find similar
Southwest
Oct 24
ECP2:00 pmPanama City NW Florida Beaches
1h 50m
STL3:50 pmLambert-St Louis
Oct 28
STL6:35 amLambert-St Louis
8h 45m
2 stops
ECP3:20 pmPanama City NW Florida Beaches
$202
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama City, Florida to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Sat 8/30

3:15 pm-5:05 pm

Nonstop1h 50m

Lambert-St Louis

Sat 9/6

3:30 pm-5:15 pm

Nonstop1h 45m

$157

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Wed 8/27

9:24 am-2:37 pm

1 stop5h 13m

Lambert-St Louis

Wed 9/3

1:26 pm-7:48 pm

1 stop6h 22m

$177

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 8/29

3:22 pm-10:59 pm

1 stop7h 37m

Lambert-St Louis

Mon 9/1

6:02 am-12:07 pm

1 stop6h 05m

$187

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Sat 8/30

5:30 am-12:11 pm

1 stop6h 41m

Lambert-St Louis

Sat 9/6

7:01 am-5:36 pm

2 stops10h 35m

$192

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Sat 8/30

3:15 pm-5:05 pm

Nonstop1h 50m

Lambert-St Louis

Sat 9/6

6:35 am-11:25 am

1 stop4h 50m

$197

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 10/24

2:00 pm-3:50 pm

Nonstop1h 50m

Lambert-St Louis

Tue 10/28

6:35 am-3:20 pm

2 stops8h 45m

$202

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 9/5

1:35 pm-3:25 pm

Nonstop1h 50m

Lambert-St Louis

Sun 9/7

8:10 am-9:55 am

Nonstop1h 45m

$208

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 8/29

9:24 am-4:06 pm

1 stop6h 42m

Lambert-St Louis

Tue 9/9

7:00 am-10:34 am

1 stop3h 34m

$248

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Wed 8/27

6:30 am-2:26 pm

1 stop7h 56m

Lambert-St Louis

Sat 9/6

6:35 am-4:20 pm

2 stops9h 45m

$302

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 8/29

5:06 pm-10:08 pm

1 stop5h 02m

Lambert-St Louis

Sun 9/7

6:35 am-1:03 pm

1 stop6h 28m

$307

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to St. Louis from

How to get the cheapest flight ticket from Panama City, Florida to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, May is the cheapest month to fly from Panama City, Florida to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $372. The month of August is another great option to travel to St. Louis, with average flight prices from Panama City, Florida averaging around $374.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $374. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $488. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest Panama City NW Florida Beaches to Lambert-St Louis flight route?

Fly from Panama City NW Florida Beaches to Lambert-St Louis for the best Panama City NW Florida Beaches - Lambert-St Louis flight prices

What cabin class options are available on Panama City NW Florida Beaches to Lambert-St Louis flights?

There are 1 cabin classes available to choose from on Panama City NW Florida Beaches to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City, Florida to St. Louis flights?

No. A direct flight is the cheapest option for a flight between Panama City, Florida to St. Louis.

How have Panama City, Florida to St. Louis flight prices changed over time?

When to book flights from Panama City, Florida to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to St. Louis (ECP to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to St. Louis

Best Price Found

$79

Fastest flight time

1h 50m

Direct flights

Every day

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Panama City, Florida in the past 72 hours is $79. The best round-trip flight deal from Panama City, Florida to St. Louis found on momondo in the last 72 hours is $157.
The fastest flight from Panama City, Florida to St. Louis takes 1h 50m
Direct flights go from Panama City, Florida to St. Louis every day.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
Search flight deals

  • How far is Panama City NW Florida Beaches to Lambert-St Louis by plane?

    There are 639.0 mi between Panama City NW Florida Beaches and Lambert-St Louis. In terms of flight time, this usually takes a little over 1h 50m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Lambert-St Louis Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Lambert-St Louis Airport refresh daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents you'll need for your trip to Lambert-St Louis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Lambert-St Louis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City, Florida to St. Louis?

  • What is the most popular airline from Panama City, Florida to St. Louis?

Best airlines flying from Panama City, Florida to St. Louis

Compare and see reviews for airlines that fly from Panama City, Florida to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $194Free CancellationRating
8.0
4,246 reviews
Search Southwest flights
DeltaPriceFrom $290Free CancellationRating
8.0
7,981 reviews
Search Delta flights

  • Southwest Flights From Panama City, Florida to St. Louis

    Southwest operates around 3 flights from Panama City, Florida to St. Louis every week. The average price of these flights found in the last 72 hours has been $410, but momondo users have found Southwest deals from Panama City, Florida to St. Louis from as low as $194 round-trip. Southwest has been scored 8.0/10 in 4,246 reviews.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
Florissant
Fenton
Collinsville
O'Fallon
Alton
St. Peters
Farmington
Wentzville
Festus
Glencoe
Eureka
Edwardsville
Clayton
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to St. Louis for you.

Can I find flights from Panama City to St. Louis with flexible booking policies on momondo?

momondo does allow users to show only those flights to St. Louis from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to St. Louis?

Once you have performed a search for Panama City to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to St. Louis right now. Can momondo alert me if prices change?

Price alerts on flights to St. Louis from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 8/5
Tue 8/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States