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Cheap flights from Orlando Airport to Knoxville from $39

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando Airport to Knoxville departing on 1/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Orlando Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:33 pm - 5:28 pm
MCO
-
TYS
1h 55mnonstop
Multiple Airlines Logo
5:59 pm - 11:59 pm
TYS
-
MCO
6h 00m1 stop
$105Multiple Airlines
Mon, Jan 12 - Sat, Jan 17
Allegiant Air Logo
8:30 am - 10:15 am
MCO
-
TYS
1h 45mnonstop
Allegiant Air Logo
6:00 am - 7:40 am
TYS
-
MCO
1h 40mnonstop
$114Allegiant Air
Fri, Jan 2 - Mon, Jan 5
Multiple Airlines Logo
6:59 pm - 8:39 am
MCO
-
TYS
13h 40m1 stop
Multiple Airlines Logo
12:55 pm - 2:43 pm
TYS
-
MCO
1h 48mnonstop
$115Multiple Airlines
Sat, Jan 24 - Mon, Jan 26
Multiple Airlines Logo
9:01 am - 5:53 pm
MCO
-
TYS
8h 52m1 stop
Multiple Airlines Logo
12:55 pm - 2:43 pm
TYS
-
MCO
1h 48mnonstop
$116Multiple Airlines
Thu, Jan 29 - Mon, Feb 2
Allegiant Air Logo
8:30 am - 10:15 am
MCO
-
TYS
1h 45mnonstop
Allegiant Air Logo
6:00 am - 7:40 am
TYS
-
MCO
1h 40mnonstop
$124Allegiant Air
Fri, Jan 2 - Mon, Jan 5
Allegiant Air Logo
8:08 pm - 9:53 pm
MCO
-
TYS
1h 45mnonstop
Allegiant Air Logo
5:38 pm - 7:18 pm
TYS
-
MCO
1h 40mnonstop
$125Allegiant Air
Fri, Dec 19 - Mon, Dec 22
Multiple Airlines Logo
6:59 pm - 11:09 am
MCO
-
TYS
16h 10m1 stop
Multiple Airlines Logo
12:55 pm - 2:43 pm
TYS
-
MCO
1h 48mnonstop
$126Multiple Airlines
Fri, Jan 23 - Mon, Jan 26
Multiple Airlines Logo
3:33 pm - 5:28 pm
MCO
-
TYS
1h 55mnonstop
Multiple Airlines Logo
7:15 am - 6:27 pm
TYS
-
MCO
11h 12m1 stop
$130Multiple Airlines
Fri, Jan 9 - Mon, Jan 12
Multiple Airlines Logo
8:45 pm - 12:05 pm
MCO
-
TYS
15h 20m1 stop
Multiple Airlines Logo
12:55 pm - 2:43 pm
TYS
-
MCO
1h 48mnonstop
$131Multiple Airlines
Thu, Jan 22 - Mon, Jan 26
Allegiant Air Logo
8:08 pm - 9:53 pm
MCO
-
TYS
1h 45mnonstop
Allegiant Air Logo
5:38 pm - 7:18 pm
TYS
-
MCO
1h 40mnonstop
$132Allegiant Air
Fri, Dec 19 - Mon, Dec 22

Allegiant Air flights from Orlando Airport to Knoxville

Our best Allegiant Air deals on Orlando Airport to Knoxville flight tickets
Allegiant Air
Dec 12
MCO3:35 pmOrlando
1h 45m
TYS5:20 pmKnoxville McGhee Tyson
Dec 15
TYS1:05 pmKnoxville McGhee Tyson
1h 40m
MCO2:45 pmOrlando
$98
Find similar
Allegiant Air
Dec 12
MCO3:35 pmOrlando
1h 45m
TYS5:20 pmKnoxville McGhee Tyson
Dec 15
TYS1:05 pmKnoxville McGhee Tyson
1h 40m
MCO2:45 pmOrlando
$113
Find similar
Allegiant Air
Jan 2
MCO8:30 amOrlando
1h 45m
TYS10:15 amKnoxville McGhee Tyson
Jan 5
TYS6:00 amKnoxville McGhee Tyson
1h 40m
MCO7:40 amOrlando
$114
Find similar

American Airlines flights from Orlando Airport to Knoxville

Our best American Airlines deals on Orlando Airport to Knoxville flight tickets
American Airlines
Jan 7
MCO5:00 amOrlando
4h 45m
1 stop
TYS9:45 amKnoxville McGhee Tyson
Jan 8
TYS2:57 pmKnoxville McGhee Tyson
4h 05m
1 stop
MCO7:02 pmOrlando
$170
Find similar
American Airlines
Jan 7
MCO5:00 amOrlando
4h 45m
1 stop
TYS9:45 amKnoxville McGhee Tyson
Jan 9
TYS7:11 pmKnoxville McGhee Tyson
4h 34m
1 stop
MCO11:45 pmOrlando
$172
Find similar
American Airlines
Jan 10
MCO5:00 amOrlando
6h 42m
1 stop
TYS11:42 amKnoxville McGhee Tyson
Jan 13
TYS3:00 pmKnoxville McGhee Tyson
5h 14m
1 stop
MCO8:14 pmOrlando
$173
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Orlando Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Orlando Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Mon 1/12

3:33 pm-5:28 pm

Nonstop1h 55m

Knoxville McGhee Tyson

Sat 1/17

5:59 pm-11:59 pm

1 stop6h 00m

$105

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Fri 1/2

8:30 am-10:15 am

Nonstop1h 45m

Knoxville McGhee Tyson

Mon 1/5

6:00 am-7:40 am

Nonstop1h 40m

$114

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Sat 1/24

6:59 pm-8:39 am

1 stop13h 40m

Knoxville McGhee Tyson

Mon 1/26

12:55 pm-2:43 pm

Nonstop1h 48m

$115

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Thu 1/29

9:01 am-5:53 pm

1 stop8h 52m

Knoxville McGhee Tyson

Mon 2/2

12:55 pm-2:43 pm

Nonstop1h 48m

$116

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Fri 1/2

8:30 am-10:15 am

Nonstop1h 45m

Knoxville McGhee Tyson

Mon 1/5

6:00 am-7:40 am

Nonstop1h 40m

$124

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Fri 12/19

8:08 pm-9:53 pm

Nonstop1h 45m

Knoxville McGhee Tyson

Mon 12/22

5:38 pm-7:18 pm

Nonstop1h 40m

$125

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Fri 1/23

6:59 pm-11:09 am

1 stop16h 10m

Knoxville McGhee Tyson

Mon 1/26

12:55 pm-2:43 pm

Nonstop1h 48m

$126

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Fri 1/9

3:33 pm-5:28 pm

Nonstop1h 55m

Knoxville McGhee Tyson

Mon 1/12

7:15 am-6:27 pm

1 stop11h 12m

$130

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Thu 1/22

8:45 pm-12:05 pm

1 stop15h 20m

Knoxville McGhee Tyson

Mon 1/26

12:55 pm-2:43 pm

Nonstop1h 48m

$131

OrlandoKnoxville

MCO - TYS

MCOTYS

Orlando

Fri 12/19

8:08 pm-9:53 pm

Nonstop1h 45m

Knoxville McGhee Tyson

Mon 12/22

5:38 pm-7:18 pm

Nonstop1h 40m

$132

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Orlando Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Orlando Airport, with most prices found around $107. If you aren’t able to travel during the month of August, then book flights to Knoxville from Orlando Airport during July instead. Flights to Knoxville in July, while not as cheap as those in August, still average around $118.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Orlando Airport to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $124. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Orlando Airport to Knoxville for around $162.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Orlando Airport to Knoxville when you can find flight prices for as low as $128. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $145.

What is the cheapest Orlando to Knoxville McGhee Tyson flight route?

Fly from Orlando to Knoxville McGhee Tyson for the best Orlando - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Orlando Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $198 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Orlando Airport for as low as $93 on momondo.

What cabin class options are available on Orlando to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Orlando to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Orlando Airport to Knoxville flight prices changed over time?

As of December 2025, prices for Orlando Airport to Knoxville flights are approximately 59% more expensive when compared to flights at the same time last year.

When to book flights from Orlando Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Airport to Knoxville (MCO to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Airport to Knoxville

Best Price Found

$70

Fastest flight time

1h 45m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Orlando Airport in the past 72 hours is $70. The best round-trip flight deal from Orlando Airport to Knoxville found on momondo in the last 72 hours is $157.
The fastest flight from Orlando Airport to Knoxville takes 1h 45m
Direct flights go from Orlando Airport to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Orlando to Knoxville McGhee Tyson by plane?

    Orlando and Knoxville McGhee Tyson are 541.8 mi apart from one another. Typically, this will take 1h 45m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Orlando Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Orlando Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Orlando Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Orlando Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando Airport to Knoxville?

  • What is the most popular airline from Orlando Airport to Knoxville?

Best airlines flying from Orlando Airport to Knoxville

Compare and see reviews for airlines that fly from Orlando Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $68Free CancellationRating
7.2
698 reviews
Search Allegiant Air flights
American AirlinesPriceFrom $212Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
DeltaPriceFrom $217Free CancellationRating
7.9
8,011 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Orlando to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Orlando to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Orlando on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Orlando to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Orlando. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Orlando to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Orlando to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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