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Cheap flights from Orlando Airport to Knoxville from $43

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Orlando Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
10:53 am - 12:41 pmMCO  Orlando-TYS Knoxville McGhee Tyson
1h 48mnonstop
Allegiant Air Logo
4:18 pm - 6:01 pmTYS  Knoxville McGhee Tyson-MCO Orlando
1h 43mnonstop
$92Allegiant Air
Fri, Sep 11 - Mon, Sep 14
Allegiant Air Logo
10:53 am - 12:41 pmMCO  Orlando-TYS Knoxville McGhee Tyson
1h 48mnonstop
Allegiant Air Logo
4:18 pm - 6:01 pmTYS  Knoxville McGhee Tyson-MCO Orlando
1h 43mnonstop
$97Allegiant Air
Fri, Sep 11 - Mon, Sep 14
Multiple Airlines Logo
9:05 am - 6:34 pmMCO  Orlando-TYS Knoxville McGhee Tyson
9h 29m1 stop Philadelphia
Multiple Airlines Logo
4:18 pm - 6:01 pmTYS  Knoxville McGhee Tyson-MCO Orlando
1h 43mnonstop
$158Multiple Airlines
Fri, Sep 11 - Mon, Sep 14
Multiple Airlines Logo
9:36 pm - 6:34 pmMCO  Orlando-TYS Knoxville McGhee Tyson
20h 58m1 stop Philadelphia
Multiple Airlines Logo
4:18 pm - 6:01 pmTYS  Knoxville McGhee Tyson-MCO Orlando
1h 43mnonstop
$163Multiple Airlines
Thu, Sep 10 - Mon, Sep 14
Southwest Logo
2:45 pm - 4:40 pmMCO  Orlando-TYS Knoxville McGhee Tyson
1h 55mnonstop
Southwest Logo
1:00 pm - 2:50 pmTYS  Knoxville McGhee Tyson-MCO Orlando
1h 50mnonstop
$193Southwest
Wed, Nov 4 - Tue, Nov 10
Southwest Logo
11:25 am - 1:05 pmMCO  Orlando-TYS Knoxville McGhee Tyson
1h 40mnonstop
Southwest Logo
12:45 pm - 2:35 pmTYS  Knoxville McGhee Tyson-MCO Orlando
1h 50mnonstop
$193Southwest
Tue, Sep 15 - Wed, Sep 16
American Airlines Logo
1:54 pm - 7:34 pmMCO  Orlando-TYS Knoxville McGhee Tyson
5h 40m1 stop Charlotte Douglas
American Airlines Logo
8:04 pm - 12:21 amTYS  Knoxville McGhee Tyson-MCO Orlando
4h 17m1 stop Charlotte Douglas
$203American Airlines
Tue, Dec 1 - Thu, Dec 3
American Airlines Logo
8:00 am - 11:44 amMCO  Orlando-TYS Knoxville McGhee Tyson
3h 44m1 stop Charlotte Douglas
American Airlines Logo
7:06 pm - 11:18 pmTYS  Knoxville McGhee Tyson-MCO Orlando
4h 12m1 stop Miami
$203American Airlines
Wed, Feb 10 - Wed, Feb 24
Delta Logo
7:45 pm - 11:57 pmMCO  Orlando-TYS Knoxville McGhee Tyson
4h 12m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 9:40 amTYS  Knoxville McGhee Tyson-MCO Orlando
4h 00m1 stop Atlanta Hartsfield-Jackson
$203Delta
Mon, Dec 7 - Wed, Dec 9
Delta Logo
8:05 am - 1:21 pmMCO  Orlando-TYS Knoxville McGhee Tyson
5h 16m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 8:57 amTYS  Knoxville McGhee Tyson-MCO Orlando
3h 17m1 stop Atlanta Hartsfield-Jackson
$203Delta
Tue, Sep 22 - Tue, Sep 29

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Allegiant Air flights from Orlando Airport to Knoxville

Our best Allegiant Air deals on Orlando Airport to Knoxville flight tickets
Allegiant Air
Sep 11
MCO10:53 amOrlando
1h 48m
TYS12:41 pmKnoxville McGhee Tyson
Sep 14
TYS4:18 pmKnoxville McGhee Tyson
1h 43m
MCO6:01 pmOrlando
$92
Allegiant Air
Sep 11
MCO10:53 amOrlando
1h 48m
TYS12:41 pmKnoxville McGhee Tyson
Sep 14
TYS4:18 pmKnoxville McGhee Tyson
1h 43m
MCO6:01 pmOrlando
$97
Allegiant Air
Aug 28
MCO5:23 pmOrlando
1h 42m
TYS7:05 pmKnoxville McGhee Tyson
Aug 31
TYS2:49 pmKnoxville McGhee Tyson
1h 42m
MCO4:31 pmOrlando
$102

Delta flights from Orlando Airport to Knoxville

Our best Delta deals on Orlando Airport to Knoxville flight tickets
Delta
Oct 13
MCO5:30 amOrlando
4h 04m
1 stop
TYS9:34 amKnoxville McGhee Tyson
Oct 14
TYS4:11 pmKnoxville McGhee Tyson
4h 50m
1 stop
MCO9:01 pmOrlando
$203
Delta
Nov 13
MCO5:30 amOrlando
5h 58m
1 stop
TYS11:28 amKnoxville McGhee Tyson
Nov 17
TYS2:40 pmKnoxville McGhee Tyson
6h 00m
1 stop
MCO8:40 pmOrlando
$213
Delta
Sep 10
MCO2:05 pmOrlando
4h 42m
1 stop
TYS6:47 pmKnoxville McGhee Tyson
Sep 14
TYS7:25 pmKnoxville McGhee Tyson
4h 57m
1 stop
MCO12:22 amOrlando
$273

momondo Fare Finder

 
Use the filters below to find and compare flights from Orlando Airport to Knoxville that are best for you.

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Price

Cheapest round-trip

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Fri 9/11

10:53 am-12:41 pm

Nonstop1h 48m

Knoxville McGhee Tyson

Mon 9/14

4:18 pm-6:01 pm

Nonstop1h 43m

$92

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Fri 9/11

10:53 am-12:41 pm

Nonstop1h 48m

Knoxville McGhee Tyson

Mon 9/14

4:18 pm-6:01 pm

Nonstop1h 43m

$97

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Fri 9/11

9:05 am-6:34 pm

1 stop9h 29m

Knoxville McGhee Tyson

Mon 9/14

4:18 pm-6:01 pm

Nonstop1h 43m

$158

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Thu 9/10

9:36 pm-6:34 pm

1 stop20h 58m

Knoxville McGhee Tyson

Mon 9/14

4:18 pm-6:01 pm

Nonstop1h 43m

$163

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Wed 11/4

2:45 pm-4:40 pm

Nonstop1h 55m

Knoxville McGhee Tyson

Tue 11/10

1:00 pm-2:50 pm

Nonstop1h 50m

$193
Quickest round-trip

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Tue 9/15

11:25 am-1:05 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Wed 9/16

12:45 pm-2:35 pm

Nonstop1h 50m

$193

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Tue 12/1

1:54 pm-7:34 pm

1 stop5h 40m

Knoxville McGhee Tyson

Thu 12/3

8:04 pm-12:21 am

1 stop4h 17m

$203

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Wed 2/10

8:00 am-11:44 am

1 stop3h 44m

Knoxville McGhee Tyson

Wed 2/24

7:06 pm-11:18 pm

1 stop4h 12m

$203

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Mon 12/7

7:45 pm-11:57 pm

1 stop4h 12m

Knoxville McGhee Tyson

Wed 12/9

5:40 am-9:40 am

1 stop4h 00m

$203

OrlandoKnoxville

MCO Orlando - TYS Knoxville McGhee Tyson

MCOTYS

Orlando

Tue 9/22

8:05 am-1:21 pm

1 stop5h 16m

Knoxville McGhee Tyson

Tue 9/29

5:40 am-8:57 am

1 stop3h 17m

$203

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Orlando Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando Airport and Knoxville?

Prices are currently low for flights on this route.

Typical prices usually range from $114 to $312.
The lowest price recently found on this route was $92.

What is the cheapest month to fly to Knoxville?

The month of June is, on average, the cheapest month to fly to Knoxville from Orlando Airport, with most prices found around $143. If you aren’t able to travel during the month of June, then book flights to Knoxville from Orlando Airport during September instead. Flights to Knoxville in September, while not as cheap as those in June, still average around $163.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Orlando Airport to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $148. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Orlando Airport to Knoxville for around $195.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Orlando Airport to Knoxville when you can find flight prices for as low as $140. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $174.

What is the cheapest Orlando to Knoxville McGhee Tyson flight route?

Fly from Orlando to Knoxville McGhee Tyson for the best Orlando - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight from Orlando Airport to Knoxville?

You are more likely to see cheaper flights to Knoxville from Orlando Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $214 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Orlando Airport for as low as $146 on momondo.

What cabin class options are available on Orlando Airport to Knoxville flights?

There is only 1 cabin class available to choose from on Orlando Airport to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando Airport to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Orlando Airport to Knoxville.

How have Orlando Airport to Knoxville flight prices changed over time?

As of August 2026, prices for Orlando Airport to Knoxville flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Orlando Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Airport to Knoxville (MCO to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Airport to Knoxville

Best Price Found

$43

Fastest flight time

1h 40m

Direct flights

Tue, Wed, Thu, Fri, Sat and Sun

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Orlando Airport in the past 72 hours is $43. The best round-trip flight deal from Orlando Airport to Knoxville found on momondo in the last 72 hours is $92.
The fastest flight from Orlando Airport to Knoxville takes 1h 40m
Direct flights go from Orlando Airport to Knoxville on Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Knoxville. From Orlando Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Orlando Airport to Knoxville

  • How far is Orlando to Knoxville McGhee Tyson by plane?

    Orlando and Knoxville McGhee Tyson are 541.8 mi apart from one another. Typically, this will take 1h 40m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Orlando Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Orlando Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Orlando Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Orlando Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando Airport to Knoxville?

  • What is the most popular airline from Orlando Airport to Knoxville?

Best airlines flying from Orlando Airport to Knoxville

Compare and see reviews for airlines that fly from Orlando Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $78Free CancellationRating
7.3
675 reviews
Search Allegiant Air flights
SouthwestPriceFrom $200Free CancellationRating
8.0
4,203 reviews
Search Southwest flights
American AirlinesPriceFrom $212Free CancellationRating
7.1
12,011 reviews
Search American Airlines flights
DeltaPriceFrom $214Free CancellationRating
7.8
8,531 reviews
Search Delta flights

  • Southwest Flights From Orlando Airport to Knoxville

    Southwest flight deals from Orlando Airport to Knoxville start from $200 round-trip. Over the 2 Southwest flights for this route in a normal week, average airfare is usually $277 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Rockford
Jefferson City

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Orlando to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Orlando to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Orlando on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Orlando to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Orlando. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Orlando to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Orlando to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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