Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Chicago O'Hare Intl Airport to Florence from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Florence departing on 5/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago O'Hare Intl Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:26 pm - 9:47 pm
ORD
-
FLO
5h 21m
1 stop
American Airlines Logo
2:35 pm - 7:48 pm
FLO
-
ORD
6h 13m
1 stop
$279American Airlines
śr., maj 6 - sob., maj 23
American Airlines Logo
1:54 pm - 9:47 pm
ORD
-
FLO
6h 53m
1 stop
American Airlines Logo
5:20 am - 8:30 am
FLO
-
ORD
4h 10m
1 stop
$348American Airlines
czw., kwi 16 - sob., kwi 18
American Airlines Logo
1:45 pm - 9:47 pm
ORD
-
FLO
7h 02m
2 stops
American Airlines Logo
2:35 pm - 7:48 pm
FLO
-
ORD
6h 13m
1 stop
$412American Airlines
śr., maj 6 - sob., maj 23
American Airlines Logo
6:40 am - 2:10 pm
ORD
-
FLO
6h 30m
2 stops
American Airlines Logo
2:35 pm - 7:54 pm
FLO
-
ORD
6h 19m
1 stop
$416American Airlines
śr., lip 8 - wt., lip 14
American Airlines Logo
1:54 pm - 9:47 pm
ORD
-
FLO
6h 53m
1 stop
American Airlines Logo
5:20 am - 11:08 am
FLO
-
ORD
6h 48m
2 stops
$455American Airlines
czw., kwi 16 - sob., kwi 18
American Airlines Logo
12:42 pm - 9:47 pm
ORD
-
FLO
8h 05m
2 stops
American Airlines Logo
5:05 am - 11:32 am
FLO
-
ORD
7h 27m
2 stops
$567American Airlines
śr., maj 6 - sob., maj 23
American Airlines Logo
1:21 pm - 9:44 pm
ORD
-
FLO
7h 23m
2 stops
American Airlines Logo
5:17 am - 11:30 am
FLO
-
ORD
7h 13m
2 stops
$589American Airlines
śr., lip 8 - wt., lip 14
American Airlines Logo
1:25 pm - 9:47 pm
ORD
-
FLO
7h 22m
2 stops
American Airlines Logo
4:02 pm - 7:22 pm
FLO
-
ORD
4h 20m
1 stop
$590American Airlines
pt., kwi 17 - wt., kwi 21
American Airlines Logo
1:25 pm - 9:47 pm
ORD
-
FLO
7h 22m
2 stops
American Airlines Logo
5:20 am - 11:08 am
FLO
-
ORD
6h 48m
2 stops
$818American Airlines
czw., kwi 16 - sob., kwi 18
American Airlines Logo
1:25 pm - 9:47 pm
ORD
-
FLO
7h 22m
2 stops
American Airlines Logo
6:15 am - 11:19 am
FLO
-
ORD
6h 04m
2 stops
$833American Airlines
pt., kwi 17 - wt., kwi 21

American Airlines flights from Chicago O'Hare Intl Airport to Florence, South Carolina

Our best American Airlines deals on Chicago O'Hare Intl Airport to Florence, South Carolina flight tickets
American Airlines
May 6
ORD3:26 pmChicago O'Hare Intl
5h 21m
1 stop
FLO9:47 pmFlorence
May 23
FLO2:35 pmFlorence
6h 13m
1 stop
ORD7:48 pmChicago O'Hare Intl
$279
American Airlines
Apr 16
ORD1:54 pmChicago O'Hare Intl
6h 53m
1 stop
FLO9:47 pmFlorence
Apr 18
FLO5:20 amFlorence
4h 10m
1 stop
ORD8:30 amChicago O'Hare Intl
$348
American Airlines
Apr 5
ORD5:00 pmChicago O'Hare Intl
5h 57m
1 stop
FLO11:57 pmFlorence
Apr 12
FLO5:20 amFlorence
4h 10m
1 stop
ORD8:30 amChicago O'Hare Intl
$357

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Kwiecień 4, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

śr. 5/6

3:26 pm-9:47 pm

1 stop5h 21m

Florence

sob. 5/23

2:35 pm-7:48 pm

1 stop6h 13m

$279
Quickest round-trip

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

czw. 4/16

1:54 pm-9:47 pm

1 stop6h 53m

Florence

sob. 4/18

5:20 am-8:30 am

1 stop4h 10m

$348

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

śr. 5/6

1:45 pm-9:47 pm

2 stops7h 02m

Florence

sob. 5/23

2:35 pm-7:48 pm

1 stop6h 13m

$412

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

śr. 7/8

6:40 am-2:10 pm

2 stops6h 30m

Florence

wt. 7/14

2:35 pm-7:54 pm

1 stop6h 19m

$416

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

czw. 4/16

1:54 pm-9:47 pm

1 stop6h 53m

Florence

sob. 4/18

5:20 am-11:08 am

2 stops6h 48m

$455

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

śr. 5/6

12:42 pm-9:47 pm

2 stops8h 05m

Florence

sob. 5/23

5:05 am-11:32 am

2 stops7h 27m

$567

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

śr. 7/8

1:21 pm-9:44 pm

2 stops7h 23m

Florence

wt. 7/14

5:17 am-11:30 am

2 stops7h 13m

$589

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

pt. 4/17

1:25 pm-9:47 pm

2 stops7h 22m

Florence

wt. 4/21

4:02 pm-7:22 pm

1 stop4h 20m

$590

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

czw. 4/16

1:25 pm-9:47 pm

2 stops7h 22m

Florence

sob. 4/18

5:20 am-11:08 am

2 stops6h 48m

$818

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

pt. 4/17

1:25 pm-9:47 pm

2 stops7h 22m

Florence

wt. 4/21

6:15 am-11:19 am

2 stops6h 04m

$833

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

See travel insights to Florence from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Chicago O'Hare Intl to Florence?

American Airlines is the most popular carrier operating from Chicago O'Hare Intl to Florence

What airlines fly to Florence, South Carolina?

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Florence, South Carolina from Chicago O'Hare Intl Airport according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 5 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Chicago O'Hare Intl Airport to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Florence, South Carolina (ORD to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Florence, South Carolina

Fastest flight time

6h 10m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Florence, South Carolina takes 6h 10m
There are no direct flights from Chicago O'Hare Intl Airport to Florence, South Carolina. There are no popular flight routes from Chicago O'Hare Intl Airport to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Chicago O'Hare Intl Airport to Florence, South Carolina

  • How far is Chicago O'Hare Intl to Florence by plane?

    Chicago O'Hare Intl and Florence are 695.4 mi apart from one another. A reasonable flight in good conditions will take 6h 10m.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Florence Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Darlington
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Chicago.

Can I find flights from Chicago to Florence with flexible booking policies on momondo?

All flight searches from Chicago to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Florence?

momondo helps you find the best flight between Chicago and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Florence right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Florence now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florence and let you know when they change.

An easier way to manage your Florence, South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
pon. 5/4
pon. 5/11
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States