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Cheap flights from Myrtle Beach to St. Louis from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to St. Louis departing on 7/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:51 am - 12:00 pm
MYR
-
STL
6h 09m
1 stop
American Airlines Logo
9:25 am - 3:31 pm
STL
-
MYR
5h 06m
1 stop
$297American Airlines
Tue, Jul 21 - Wed, Jul 22
American Airlines Logo
4:23 pm - 11:42 pm
MYR
-
STL
8h 19m
1 stop
American Airlines Logo
10:22 am - 4:25 pm
STL
-
MYR
5h 03m
1 stop
$299American Airlines
Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
10:23 am - 10:00 pm
MYR
-
STL
12h 37m
2 stops
United Airlines Logo
8:00 am - 2:53 pm
STL
-
MYR
5h 53m
1 stop
$304United Airlines
Thu, Aug 27 - Tue, Sep 1
Southwest Logo
7:15 pm - 11:05 pm
MYR
-
STL
4h 50m
1 stop
Southwest Logo
4:45 pm - 7:40 pm
STL
-
MYR
1h 55mnonstop
$306Southwest
Tue, Jul 14 - Sat, Jul 18
Delta Logo
6:00 am - 9:43 am
MYR
-
STL
4h 43m
1 stop
Delta Logo
7:08 am - 1:00 pm
STL
-
MYR
4h 52m
1 stop
$307Delta
Tue, Jul 14 - Tue, Jul 28
Southwest Logo
2:25 pm - 8:00 pm
MYR
-
STL
6h 35m
2 stops
Southwest Logo
10:45 am - 7:20 pm
STL
-
MYR
7h 35m
2 stops
$309Southwest
Wed, Sep 16 - Tue, Sep 22
Multiple Airlines Logo
9:53 pm - 8:57 am
MYR
-
STL
36h 04m
2 stops
Multiple Airlines Logo
4:09 pm - 9:05 am
STL
-
MYR
15h 56m
1 stop
$312Multiple Airlines
Sat, Jul 11 - Tue, Jul 21
Delta Logo
4:34 pm - 10:15 pm
MYR
-
STL
6h 41m
1 stop
Delta Logo
7:08 am - 1:00 pm
STL
-
MYR
4h 52m
1 stop
$315Delta
Tue, Jul 14 - Tue, Jul 28
Southwest Logo
1:55 pm - 3:00 pm
MYR
-
STL
2h 05mnonstop
Southwest Logo
6:05 am - 1:50 pm
STL
-
MYR
6h 45m
1 stop
$318Southwest
Thu, Aug 27 - Mon, Aug 31
Multiple Airlines Logo
4:13 pm - 11:59 pm
MYR
-
STL
8h 46m
1 stop
Multiple Airlines Logo
4:57 pm - 9:08 pm
STL
-
MYR
27h 11m
2 stops
$319Multiple Airlines
Tue, Jul 14 - Fri, Jul 24

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American Airlines flights from Myrtle Beach to St. Louis

Our best American Airlines deals on Myrtle Beach to St. Louis flight tickets
American Airlines
Jul 21
MYR6:51 amMyrtle Beach Intl
6h 09m
1 stop
STL12:00 pmLambert-St Louis
Jul 22
STL9:25 amLambert-St Louis
5h 06m
1 stop
MYR3:31 pmMyrtle Beach Intl
$297
American Airlines
Aug 27
MYR4:23 pmMyrtle Beach Intl
8h 19m
1 stop
STL11:42 pmLambert-St Louis
Aug 31
STL10:22 amLambert-St Louis
5h 03m
1 stop
MYR4:25 pmMyrtle Beach Intl
$299
American Airlines
Jul 14
MYR11:19 amMyrtle Beach Intl
6h 43m
1 stop
STL5:02 pmLambert-St Louis
Jul 21
STL6:55 amLambert-St Louis
4h 31m
1 stop
MYR12:26 pmMyrtle Beach Intl
$368

United Airlines flights from Myrtle Beach to St. Louis

Our best United Airlines deals on Myrtle Beach to St. Louis flight tickets
United Airlines
Aug 27
MYR10:23 amMyrtle Beach Intl
12h 37m
2 stops
STL10:00 pmLambert-St Louis
Sep 1
STL8:00 amLambert-St Louis
5h 53m
1 stop
MYR2:53 pmMyrtle Beach Intl
$304
United Airlines
Aug 27
MYR10:23 amMyrtle Beach Intl
12h 37m
2 stops
STL10:00 pmLambert-St Louis
Aug 31
STL8:00 amLambert-St Louis
5h 53m
1 stop
MYR2:53 pmMyrtle Beach Intl
$322
United Airlines
Jul 11
MYR11:30 amMyrtle Beach Intl
7h 43m
1 stop
STL6:13 pmLambert-St Louis
Jul 23
STL6:00 amLambert-St Louis
7h 19m
1 stop
MYR2:19 pmMyrtle Beach Intl
$387

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from Myrtle Beach to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 7/21

6:51 am-12:00 pm

1 stop6h 09m

Lambert-St Louis

Wed 7/22

9:25 am-3:31 pm

1 stop5h 06m

$297

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 8/27

4:23 pm-11:42 pm

1 stop8h 19m

Lambert-St Louis

Mon 8/31

10:22 am-4:25 pm

1 stop5h 03m

$299

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 8/27

10:23 am-10:00 pm

2 stops12h 37m

Lambert-St Louis

Tue 9/1

8:00 am-2:53 pm

1 stop5h 53m

$304
Quickest round-trip

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 7/14

7:15 pm-11:05 pm

1 stop4h 50m

Lambert-St Louis

Sat 7/18

4:45 pm-7:40 pm

Nonstop1h 55m

$306

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 7/14

6:00 am-9:43 am

1 stop4h 43m

Lambert-St Louis

Tue 7/28

7:08 am-1:00 pm

1 stop4h 52m

$307

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Wed 9/16

2:25 pm-8:00 pm

2 stops6h 35m

Lambert-St Louis

Tue 9/22

10:45 am-7:20 pm

2 stops7h 35m

$309

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 7/11

9:53 pm-8:57 am

2 stops36h 04m

Lambert-St Louis

Tue 7/21

4:09 pm-9:05 am

1 stop15h 56m

$312

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 7/14

4:34 pm-10:15 pm

1 stop6h 41m

Lambert-St Louis

Tue 7/28

7:08 am-1:00 pm

1 stop4h 52m

$315

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 8/27

1:55 pm-3:00 pm

Nonstop2h 05m

Lambert-St Louis

Mon 8/31

6:05 am-1:50 pm

1 stop6h 45m

$318

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 7/14

4:13 pm-11:59 pm

1 stop8h 46m

Lambert-St Louis

Fri 7/24

4:57 pm-9:08 pm

2 stops27h 11m

$319

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Myrtle Beach to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Myrtle Beach to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $225. The month of October is another great option to travel to St. Louis, with average flight prices from Myrtle Beach averaging around $296.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Saturday when prices can be found for as low as $392. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $502. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Myrtle Beach in the morning is the least expensive time of day to depart. momondo users have found prices as low as $487 when looking at flights departing in the morning. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $549 per ticket.

What is the cheapest Myrtle Beach Intl to Lambert-St Louis flight route?

Fly from Myrtle Beach Intl to Lambert-St Louis for the best Myrtle Beach Intl - Lambert-St Louis flight prices

What cabin class options are available on Myrtle Beach to St. Louis flights?

There is only 1 cabin class available to choose from on Myrtle Beach to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to St. Louis flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to St. Louis.

How have Myrtle Beach to St. Louis flight prices changed over time?

When to book flights from Myrtle Beach to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to St. Louis (MYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to St. Louis

Best Price Found

$203

Fastest flight time

2h 00m

Direct flights

Mon, Tue, Fri, Sat and Sun

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Myrtle Beach in the past 72 hours is $203. The best round-trip flight deal from Myrtle Beach to St. Louis found on momondo in the last 72 hours is $465.
The fastest flight from Myrtle Beach to St. Louis takes 2h 00m
Direct flights go from Myrtle Beach to St. Louis on Monday, Tuesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in St. Louis. From Myrtle Beach there are direct flights to Lambert-St Louis (STL).
Search flight deals

Frequently asked questions about flying from Myrtle Beach to St. Louis

  • How far is Myrtle Beach Intl to Lambert-St Louis by plane?

    There are 716.1 mi between Myrtle Beach Intl and Lambert-St Louis. Typically, this will take 2h 00m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

    Prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Myrtle Beach to St. Louis?

  • What is the most popular airline from Myrtle Beach to St. Louis?

Best airlines flying from Myrtle Beach to St. Louis

Compare and see reviews for airlines that fly from Myrtle Beach to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $225Free CancellationRating
7.8
8,440 reviews
Search Delta flights
American AirlinesPriceFrom $260Free CancellationRating
7.1
11,756 reviews
Search American Airlines flights
SouthwestPriceFrom $307Free CancellationRating
7.9
4,243 reviews
Search Southwest flights

  • Southwest Flights From Myrtle Beach to St. Louis

    The lowest priced Southwest flight from Myrtle Beach to St. Louis from the last 72 hours was $307. Generally, Southwest has 3 flights on this route every week with an average price of $361. Southwest is rated 7.9/10 by our users.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
Maryland Heights
Florissant
O'Fallon
Collinsville
St. Peters
Alton
Wentzville
Farmington
Fenton
Clayton
Festus
Eureka
Litchfield
Edwardsville
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to St. Louis for you.

Can I find flights from Myrtle Beach to St. Louis with flexible booking policies on momondo?

momondo does allow users to show only those flights to St. Louis from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to St. Louis?

Once all potential Myrtle Beach to St. Louis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.

An easier way to manage your St. Louis trip

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