What airlines fly to St. Louis?

American Airlines, Southwest and Delta are the top three most popular airlines that fly to St. Louis from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 3 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

Prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

As of January 2026, there are 3 operators available to choose from for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport.

How old do you have to be to fly from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Lambert-St Louis Airport.

What documentation or ID do you need to fly to Lambert-St Louis Airport?

The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$98 Cheap Flights from Myrtle Beach to St. Louis in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Myrtle Beach to St. Louis

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:39 pm - 10:27 pm

MYR

STL

10h 48m

1 stop

4:51 pm - 2:55 pm

STL

MYR

21h 04m

2 stops

$231Multiple Airlines

Tue, Mar 3 - Tue, Mar 10

1:07 pm - 10:27 pm

MYR

STL

10h 20m

1 stop

8:17 pm - 12:25 pm

STL

MYR

39h 08m

2 stops

$236Multiple Airlines

Tue, Feb 10 - Sat, Feb 14

12:05 pm - 11:19 pm

MYR

STL

12h 14m

1 stop

12:16 pm - 2:32 pm

STL

MYR

25h 16m

2 stops

$256Multiple Airlines

Tue, Mar 17 - Fri, Mar 20

5:18 pm - 11:22 pm

MYR

STL

7h 04m

1 stop

6:06 am - 11:52 am

STL

MYR

4h 46m

1 stop

$283American Airlines

Sat, Feb 14 - Sat, Feb 21

3:17 pm - 6:07 pm

MYR

STL

3h 50m

1 stop

1:30 pm - 10:50 pm

STL

MYR

8h 20m

2 stops

$288American Airlines

Sat, Feb 14 - Sat, Feb 21

9:10 am - 6:00 pm

MYR

STL

9h 50m

2 stops

1:30 pm - 11:55 pm

STL

MYR

9h 25m

2 stops

$294American Airlines

Sat, Feb 14 - Sat, Feb 21

9:09 am - 6:51 am

MYR

STL

46h 42m

2 stops

4:21 pm - 8:50 am

STL

MYR

15h 29m

1 stop

$320Multiple Airlines

Mon, Mar 2 - Sat, Mar 7

3:00 pm - 9:00 pm

MYR

STL

7h 00m

1 stop

7:30 am - 3:05 pm

STL

MYR

6h 35m

1 stop

$343Southwest

Tue, Mar 3 - Tue, Mar 10

12:39 pm - 11:59 pm

MYR

STL

12h 20m

1 stop

3:49 pm - 8:13 am

STL

MYR

39h 24m

2 stops

$347Multiple Airlines

Sun, Feb 22 - Sun, Mar 1

6:40 pm - 10:40 pm

MYR

STL

5h 00m

1 stop

3:45 pm - 6:40 pm

STL

MYR

1h 55mnonstop

$349Southwest

Mon, Mar 2 - Sat, Mar 7

American Airlines flights from Myrtle Beach to St. Louis

Our best American Airlines deals on Myrtle Beach to St. Louis flight tickets

American Airlines

Feb 14

MYR5:18 pmMyrtle Beach Intl

7h 04m

1 stop

STL11:22 pmLambert-St Louis

Feb 21

STL6:06 amLambert-St Louis

4h 46m

1 stop

MYR11:52 amMyrtle Beach Intl

$283

American Airlines

Feb 14

MYR3:17 pmMyrtle Beach Intl

3h 50m

1 stop

STL6:07 pmLambert-St Louis

Feb 21

STL1:30 pmLambert-St Louis

8h 20m

2 stops

MYR10:50 pmMyrtle Beach Intl

$288

American Airlines

Feb 14

MYR9:10 amMyrtle Beach Intl

9h 50m

2 stops

STL6:00 pmLambert-St Louis

Feb 21

STL1:30 pmLambert-St Louis

9h 25m

2 stops

MYR11:55 pmMyrtle Beach Intl

$294

Southwest flights from Myrtle Beach to St. Louis

Our best Southwest deals on Myrtle Beach to St. Louis flight tickets

Southwest

Mar 3

MYR3:00 pmMyrtle Beach Intl

7h 00m

1 stop

STL9:00 pmLambert-St Louis

Mar 10

STL7:30 amLambert-St Louis

6h 35m

1 stop

MYR3:05 pmMyrtle Beach Intl

$343

Southwest

Mar 2

MYR6:40 pmMyrtle Beach Intl

5h 00m

1 stop

STL10:40 pmLambert-St Louis

Mar 7

STL3:45 pmLambert-St Louis

1h 55m

MYR6:40 pmMyrtle Beach Intl

$349

Southwest

Mar 17

MYR7:45 amMyrtle Beach Intl

8h 45m

1 stop

STL3:30 pmLambert-St Louis

Mar 20

STL4:45 pmLambert-St Louis

4h 50m

1 stop

MYR10:35 pmMyrtle Beach Intl

$352

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 3/3

12:39 pm-10:27 pm

1 stop10h 48m

Lambert-St Louis

Tue 3/10

4:51 pm-2:55 pm

2 stops21h 04m

$231

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 2/10

1:07 pm-10:27 pm

1 stop10h 20m

Lambert-St Louis

Sat 2/14

8:17 pm-12:25 pm

2 stops39h 08m

$236

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 3/17

12:05 pm-11:19 pm

1 stop12h 14m

Lambert-St Louis

Fri 3/20

12:16 pm-2:32 pm

2 stops25h 16m

$256

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 2/14

5:18 pm-11:22 pm

1 stop7h 04m

Lambert-St Louis

Sat 2/21

6:06 am-11:52 am

1 stop4h 46m

$283

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 2/14

3:17 pm-6:07 pm

1 stop3h 50m

Lambert-St Louis

Sat 2/21

1:30 pm-10:50 pm

2 stops8h 20m

$288

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 2/14

9:10 am-6:00 pm

2 stops9h 50m

Lambert-St Louis

Sat 2/21

1:30 pm-11:55 pm

2 stops9h 25m

$294

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Mon 3/2

9:09 am-6:51 am

2 stops46h 42m

Lambert-St Louis

Sat 3/7

4:21 pm-8:50 am

1 stop15h 29m

$320

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 3/3

3:00 pm-9:00 pm

1 stop7h 00m

Lambert-St Louis

Tue 3/10

7:30 am-3:05 pm

1 stop6h 35m

$343

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sun 2/22

12:39 pm-11:59 pm

1 stop12h 20m

Lambert-St Louis

Sun 3/1

3:49 pm-8:13 am

2 stops39h 24m

$347

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Mon 3/2

6:40 pm-10:40 pm

1 stop5h 00m

Lambert-St Louis

Sat 3/7

3:45 pm-6:40 pm

Nonstop1h 55m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Myrtle Beach to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $316. The month of July is another great option to travel to St. Louis, with average flight prices from Myrtle Beach averaging around $322.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Sunday when prices can be found for as low as $502. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $554. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest Myrtle Beach Intl to Lambert-St Louis flight route?

Fly from Myrtle Beach Intl to Lambert-St Louis for the best Myrtle Beach Intl - Lambert-St Louis flight prices

What cabin class options are available on Myrtle Beach Intl to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on Myrtle Beach Intl to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Myrtle Beach to St. Louis flight prices changed over time?

When to book flights from Myrtle Beach to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to St. Louis according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Myrtle Beach to St. Louis (MYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to St. Louis

Fastest flight time	4h 48m
Direct flights	Sun
Airports in St. Louis	1 airport

The fastest flight from Myrtle Beach to St. Louis takes 4h 48m

Direct flights go from Myrtle Beach to St. Louis on Sunday. There are no airlines offering direct flights.

There is 1 airport in St. Louis. From Myrtle Beach there are direct flights to Lambert-St Louis (STL).

Search flight deals

How far is Myrtle Beach Intl to Lambert-St Louis by plane?
There are 716.1 mi between Myrtle Beach Intl and Lambert-St Louis. Typically, this will take 4h 48m by plane in normal conditions.
When did momondo last update prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?
Prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?
As of January 2026, there are 3 operators available to choose from for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport.
How old do you have to be to fly from Myrtle Beach Intl Airport to Lambert-St Louis Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Lambert-St Louis Airport.
What documentation or ID do you need to fly to Lambert-St Louis Airport?
The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Myrtle Beach to St. Louis?
momondo data reveals that the most frequently booked plane model on the route from Myrtle Beach to St. Louis is Boeing 737 MAX 8, representing 14.29% of all bookings. The subsequent popular models are Airbus A318/A319/A320/A321 at 14.29%, Airbus A319 at 14.29%, and Embraer 175 (Enhanced Winglets) at 14.29%.
What is the most popular airline from Myrtle Beach to St. Louis?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Myrtle Beach to St. Louis is American Airlines (39% of total bookings). The next most popular airlines are Southwest (38%) and Delta (23%).

Best airlines flying from Myrtle Beach to St. Louis

Compare and see reviews for airlines that fly from Myrtle Beach to St. Louis with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $128	Free Cancellation	Rating 7.9 8,124 reviews	Search Delta flights
American Airlines	PriceFrom $260	Free Cancellation	Rating 7.2 11,199 reviews	Search American Airlines flights
Southwest	PriceFrom $310	Free Cancellation	Rating 8.0 4,267 reviews	Search Southwest flights

St. Charles

Chesterfield

Hermann

Fairview Heights

Maryland Heights

Florissant

O'Fallon

Collinsville

Fenton

St. Peters

Wentzville

Alton

Farmington

Clayton

Edwardsville

Eureka

Festus

Glencoe

Litchfield

Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to St. Louis for you.

Can I find flights from Myrtle Beach to St. Louis with flexible booking policies on momondo?

momondo does allow users to show only those flights to St. Louis from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to St. Louis?

Once all potential Myrtle Beach to St. Louis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.