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Cheap flights from Myrtle Beach to St. Louis from $124

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to St. Louis departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:27 am - 11:19 pm
MYR
-
STL
13h 52m
1 stop
Multiple Airlines Logo
5:27 pm - 8:58 pm
STL
-
MYR
26h 31m
2 stops
$337Multiple Airlines
Thu, Apr 30 - Wed, May 6
Southwest Logo
1:00 pm - 2:20 pm
MYR
-
STL
2h 20mnonstop
Southwest Logo
11:00 am - 4:10 pm
STL
-
MYR
4h 10m
1 stop
$343Southwest
Sat, May 9 - Sun, May 10
United Airlines Logo
3:14 pm - 9:13 pm
MYR
-
STL
6h 59m
1 stop
United Airlines Logo
8:21 am - 2:18 pm
STL
-
MYR
4h 57m
1 stop
$346United Airlines
Sat, May 9 - Sun, May 10
Southwest Logo
7:20 pm - 11:25 pm
MYR
-
STL
5h 05m
1 stop
Southwest Logo
1:15 pm - 8:30 pm
STL
-
MYR
6h 15m
1 stop
$350Southwest
Fri, May 29 - Tue, Jun 2
Delta Logo
12:05 pm - 7:26 pm
MYR
-
STL
8h 21m
1 stop
Delta Logo
6:48 am - 11:55 am
STL
-
MYR
4h 07m
1 stop
$351Delta
Fri, Apr 17 - Mon, Apr 20
Southwest Logo
7:20 pm - 11:25 pm
MYR
-
STL
5h 05m
1 stop
Southwest Logo
11:35 am - 8:30 pm
STL
-
MYR
7h 55m
2 stops
$355Southwest
Fri, May 29 - Tue, Jun 2
American Airlines Logo
10:28 am - 3:13 pm
MYR
-
STL
5h 45m
1 stop
American Airlines Logo
12:27 pm - 10:24 pm
STL
-
MYR
8h 57m
2 stops
$356American Airlines
Fri, Apr 17 - Mon, Apr 20
Southwest Logo
1:00 pm - 2:20 pm
MYR
-
STL
2h 20mnonstop
Southwest Logo
7:05 am - 12:10 pm
STL
-
MYR
4h 05m
1 stop
$358Southwest
Sat, Apr 18 - Sat, Apr 25
Southwest Logo
1:45 pm - 8:55 pm
MYR
-
STL
8h 10m
2 stops
Southwest Logo
11:35 am - 8:30 pm
STL
-
MYR
7h 55m
2 stops
$360Southwest
Fri, May 29 - Tue, Jun 2
American Airlines Logo
11:11 am - 4:41 pm
MYR
-
STL
6h 30m
2 stops
American Airlines Logo
12:27 pm - 10:24 pm
STL
-
MYR
8h 57m
2 stops
$361American Airlines
Fri, Apr 17 - Mon, Apr 20

Southwest flights from Myrtle Beach to St. Louis

Our best Southwest deals on Myrtle Beach to St. Louis flight tickets
Southwest
May 9
MYR1:00 pmMyrtle Beach Intl
2h 20m
STL2:20 pmLambert-St Louis
May 10
STL11:00 amLambert-St Louis
4h 10m
1 stop
MYR4:10 pmMyrtle Beach Intl
$343
Southwest
May 29
MYR7:20 pmMyrtle Beach Intl
5h 05m
1 stop
STL11:25 pmLambert-St Louis
Jun 2
STL1:15 pmLambert-St Louis
6h 15m
1 stop
MYR8:30 pmMyrtle Beach Intl
$350
Southwest
May 29
MYR7:20 pmMyrtle Beach Intl
5h 05m
1 stop
STL11:25 pmLambert-St Louis
Jun 2
STL11:35 amLambert-St Louis
7h 55m
2 stops
MYR8:30 pmMyrtle Beach Intl
$355

American Airlines flights from Myrtle Beach to St. Louis

Our best American Airlines deals on Myrtle Beach to St. Louis flight tickets
American Airlines
Apr 17
MYR10:28 amMyrtle Beach Intl
5h 45m
1 stop
STL3:13 pmLambert-St Louis
Apr 20
STL12:27 pmLambert-St Louis
8h 57m
2 stops
MYR10:24 pmMyrtle Beach Intl
$356
American Airlines
Apr 17
MYR11:11 amMyrtle Beach Intl
6h 30m
2 stops
STL4:41 pmLambert-St Louis
Apr 20
STL12:27 pmLambert-St Louis
8h 57m
2 stops
MYR10:24 pmMyrtle Beach Intl
$361
American Airlines
Jun 24
MYR6:06 pmMyrtle Beach Intl
6h 48m
2 stops
STL11:54 pmLambert-St Louis
Jun 30
STL1:45 pmLambert-St Louis
7h 02m
2 stops
MYR9:47 pmMyrtle Beach Intl
$378

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Myrtle Beach to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 4/30

10:27 am-11:19 pm

1 stop13h 52m

Lambert-St Louis

Wed 5/6

5:27 pm-8:58 pm

2 stops26h 31m

$337

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 5/9

1:00 pm-2:20 pm

Nonstop2h 20m

Lambert-St Louis

Sun 5/10

11:00 am-4:10 pm

1 stop4h 10m

$343

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 5/9

3:14 pm-9:13 pm

1 stop6h 59m

Lambert-St Louis

Sun 5/10

8:21 am-2:18 pm

1 stop4h 57m

$346

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Fri 5/29

7:20 pm-11:25 pm

1 stop5h 05m

Lambert-St Louis

Tue 6/2

1:15 pm-8:30 pm

1 stop6h 15m

$350

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Fri 4/17

12:05 pm-7:26 pm

1 stop8h 21m

Lambert-St Louis

Mon 4/20

6:48 am-11:55 am

1 stop4h 07m

$351

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Fri 5/29

7:20 pm-11:25 pm

1 stop5h 05m

Lambert-St Louis

Tue 6/2

11:35 am-8:30 pm

2 stops7h 55m

$355

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Fri 4/17

10:28 am-3:13 pm

1 stop5h 45m

Lambert-St Louis

Mon 4/20

12:27 pm-10:24 pm

2 stops8h 57m

$356
Quickest round-trip

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 4/18

1:00 pm-2:20 pm

Nonstop2h 20m

Lambert-St Louis

Sat 4/25

7:05 am-12:10 pm

1 stop4h 05m

$358

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Fri 5/29

1:45 pm-8:55 pm

2 stops8h 10m

Lambert-St Louis

Tue 6/2

11:35 am-8:30 pm

2 stops7h 55m

$360

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Fri 4/17

11:11 am-4:41 pm

2 stops6h 30m

Lambert-St Louis

Mon 4/20

12:27 pm-10:24 pm

2 stops8h 57m

$361

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Myrtle Beach to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Myrtle Beach to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $316. The month of July is another great option to travel to St. Louis, with average flight prices from Myrtle Beach averaging around $322.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Saturday when prices can be found for as low as $456. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $487. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest Myrtle Beach Intl to Lambert-St Louis flight route?

Fly from Myrtle Beach Intl to Lambert-St Louis for the best Myrtle Beach Intl - Lambert-St Louis flight prices

What cabin class options are available on Myrtle Beach Intl to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on Myrtle Beach Intl to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Myrtle Beach to St. Louis flight prices changed over time?

When to book flights from Myrtle Beach to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to St. Louis (MYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to St. Louis

Fastest flight time

2h 05m

Direct flights

Fri, Sat and Sun

Airports in St. Louis

1 airport
The fastest flight from Myrtle Beach to St. Louis takes 2h 05m
Direct flights go from Myrtle Beach to St. Louis on Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in St. Louis. From Myrtle Beach there are direct flights to Lambert-St Louis (STL).
Search flight deals

  • How far is Myrtle Beach Intl to Lambert-St Louis by plane?

    There are 716.1 mi between Myrtle Beach Intl and Lambert-St Louis. Typically, this will take 2h 05m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

    Prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Myrtle Beach to St. Louis?

  • What is the most popular airline from Myrtle Beach to St. Louis?

Best airlines flying from Myrtle Beach to St. Louis

Compare and see reviews for airlines that fly from Myrtle Beach to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $128Free CancellationRating
7.9
8,319 reviews
Search Delta flights
American AirlinesPriceFrom $260Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights
SouthwestPriceFrom $307Free CancellationRating
8.0
4,324 reviews
Search Southwest flights

  • Southwest Flights From Myrtle Beach to St. Louis

    The lowest priced Southwest flight from Myrtle Beach to St. Louis from the last 72 hours was $307. Generally, Southwest has 1 flight on this route every week with an average price of $382. Southwest is rated 8.0/10 by our users.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Collinsville
St. Peters
Wentzville
Alton
Fenton
Farmington
Clayton
Festus
Edwardsville
Eureka
Litchfield
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to St. Louis for you.

Can I find flights from Myrtle Beach to St. Louis with flexible booking policies on momondo?

momondo does allow users to show only those flights to St. Louis from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to St. Louis?

Once all potential Myrtle Beach to St. Louis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.

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