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Cheap flights from Myrtle Beach to St. Louis from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to St. Louis departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:00 am - 11:33 pm
MYR
-
STL
14h 33m2 stops
Multiple Airlines Logo
5:42 pm - 9:50 am
STL
-
MYR
15h 08m1 stop
$228Multiple Airlines
Tue, Feb 3 - Sat, Feb 7
American Airlines Logo
12:14 pm - 5:23 pm
MYR
-
STL
6h 09m1 stop
American Airlines Logo
7:15 am - 4:54 pm
STL
-
MYR
8h 39m1 stop
$358American Airlines
Tue, Jan 13 - Wed, Jan 14
American Airlines Logo
8:00 am - 2:57 pm
MYR
-
STL
7h 57m2 stops
American Airlines Logo
7:15 am - 4:54 pm
STL
-
MYR
8h 39m1 stop
$363American Airlines
Tue, Jan 13 - Wed, Jan 14
American Airlines Logo
8:00 am - 2:50 pm
MYR
-
STL
7h 50m2 stops
American Airlines Logo
6:00 am - 1:23 pm
STL
-
MYR
6h 23m2 stops
$369American Airlines
Tue, Jan 13 - Wed, Jan 14
Delta Logo
12:15 pm - 4:52 pm
MYR
-
STL
5h 37m1 stop
Delta Logo
10:13 am - 5:58 pm
STL
-
MYR
6h 45m1 stop
$387Delta
Thu, Feb 19 - Sun, Feb 22
Southwest Logo
8:20 am - 3:20 pm
MYR
-
STL
8h 00m2 stops
Southwest Logo
5:50 am - 12:15 pm
STL
-
MYR
5h 25m1 stop
$392Southwest
Thu, Feb 19 - Sun, Feb 22
American Airlines Logo
5:11 am - 12:29 pm
MYR
-
STL
8h 18m2 stops
American Airlines Logo
6:00 am - 2:28 pm
STL
-
MYR
7h 28m2 stops
$397American Airlines
Thu, Feb 19 - Sun, Feb 22
Delta Logo
2:19 pm - 5:53 pm
MYR
-
STL
4h 34m1 stop
Delta Logo
6:30 am - 1:39 pm
STL
-
MYR
6h 09m1 stop
$417Delta
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
9:15 am - 12:05 pm
MYR
-
STL
3h 50m1 stop
American Airlines Logo
11:14 am - 6:56 pm
STL
-
MYR
6h 42m2 stops
$422American Airlines
Thu, Apr 9 - Mon, Apr 13
Southwest Logo
11:05 am - 5:30 pm
MYR
-
STL
7h 25m2 stops
Southwest Logo
10:25 am - 7:35 pm
STL
-
MYR
8h 10m2 stops
$427Southwest
Tue, Feb 3 - Sat, Feb 7

United Airlines flights from Myrtle Beach to St. Louis

Our best United Airlines deals on Myrtle Beach to St. Louis flight tickets
United Airlines
Jan 26
MYR1:25 pmMyrtle Beach Intl
10h 33m
2 stops
STL10:58 pmLambert-St Louis
Jan 29
STL9:57 amLambert-St Louis
25h 44m
2 stops
MYR12:41 pmMyrtle Beach Intl
$627
Find similar
United Airlines
Jan 26
MYR1:25 pmMyrtle Beach Intl
10h 33m
2 stops
STL10:58 pmLambert-St Louis
Jan 29
STL9:57 amLambert-St Louis
25h 44m
2 stops
MYR12:41 pmMyrtle Beach Intl
$662
Find similar

Delta flights from Myrtle Beach to St. Louis

Our best Delta deals on Myrtle Beach to St. Louis flight tickets
Delta
Feb 19
MYR12:15 pmMyrtle Beach Intl
5h 37m
1 stop
STL4:52 pmLambert-St Louis
Feb 22
STL10:13 amLambert-St Louis
6h 45m
1 stop
MYR5:58 pmMyrtle Beach Intl
$387
Find similar
Delta
Apr 9
MYR2:19 pmMyrtle Beach Intl
4h 34m
1 stop
STL5:53 pmLambert-St Louis
Apr 13
STL6:30 amLambert-St Louis
6h 09m
1 stop
MYR1:39 pmMyrtle Beach Intl
$417
Find similar
Delta
Dec 29
MYR11:09 amMyrtle Beach Intl
4h 23m
1 stop
STL2:32 pmLambert-St Louis
Jan 1
STL7:00 amLambert-St Louis
4h 31m
1 stop
MYR12:31 pmMyrtle Beach Intl
$477
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 2/3

10:00 am-11:33 pm

2 stops14h 33m

Lambert-St Louis

Sat 2/7

5:42 pm-9:50 am

1 stop15h 08m

$228

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 1/13

12:14 pm-5:23 pm

1 stop6h 09m

Lambert-St Louis

Wed 1/14

7:15 am-4:54 pm

1 stop8h 39m

$358

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 1/13

8:00 am-2:57 pm

2 stops7h 57m

Lambert-St Louis

Wed 1/14

7:15 am-4:54 pm

1 stop8h 39m

$363

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 1/13

8:00 am-2:50 pm

2 stops7h 50m

Lambert-St Louis

Wed 1/14

6:00 am-1:23 pm

2 stops6h 23m

$369

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 2/19

12:15 pm-4:52 pm

1 stop5h 37m

Lambert-St Louis

Sun 2/22

10:13 am-5:58 pm

1 stop6h 45m

$387

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 2/19

8:20 am-3:20 pm

2 stops8h 00m

Lambert-St Louis

Sun 2/22

5:50 am-12:15 pm

1 stop5h 25m

$392

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 2/19

5:11 am-12:29 pm

2 stops8h 18m

Lambert-St Louis

Sun 2/22

6:00 am-2:28 pm

2 stops7h 28m

$397

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 4/9

2:19 pm-5:53 pm

1 stop4h 34m

Lambert-St Louis

Mon 4/13

6:30 am-1:39 pm

1 stop6h 09m

$417

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 4/9

9:15 am-12:05 pm

1 stop3h 50m

Lambert-St Louis

Mon 4/13

11:14 am-6:56 pm

2 stops6h 42m

$422

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 2/3

11:05 am-5:30 pm

2 stops7h 25m

Lambert-St Louis

Sat 2/7

10:25 am-7:35 pm

2 stops8h 10m

$427

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Myrtle Beach to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Myrtle Beach to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $316. The month of July is another great option to travel to St. Louis, with average flight prices from Myrtle Beach averaging around $322.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Tuesday when prices can be found for as low as $319. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $554. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Myrtle Beach in the evening is the least expensive time of day to depart. momondo users have found prices as low as $341 when looking at flights departing in the evening. In the morning is when there is more demand to fly to St. Louis, so prices are often more expensive at around $527 per ticket.

What is the cheapest Myrtle Beach Intl to Lambert-St Louis flight route?

Fly from Myrtle Beach Intl to Lambert-St Louis for the best Myrtle Beach Intl - Lambert-St Louis flight prices

What cabin class options are available on Myrtle Beach Intl to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on Myrtle Beach Intl to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Myrtle Beach to St. Louis flight prices changed over time?

When to book flights from Myrtle Beach to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to St. Louis (MYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to St. Louis

Fastest flight time

2h 05m

Direct flights

Sun

Airports in St. Louis

1 airport
The fastest flight from Myrtle Beach to St. Louis takes 2h 05m
Direct flights go from Myrtle Beach to St. Louis on Sunday. There are no airlines offering direct flights.
There is 1 airport in St. Louis. From Myrtle Beach there are direct flights to Lambert-St Louis (STL).
Search flight deals

  • How far is Myrtle Beach Intl to Lambert-St Louis by plane?

    There are 716.1 mi between Myrtle Beach Intl and Lambert-St Louis. Typically, this will take 2h 05m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

    Prices for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Myrtle Beach to St. Louis?

  • What is the most popular airline from Myrtle Beach to St. Louis?

Best airlines flying from Myrtle Beach to St. Louis

Compare and see reviews for airlines that fly from Myrtle Beach to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $168Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $260Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights
SouthwestPriceFrom $310Free CancellationRating
7.9
4,250 reviews
Search Southwest flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
Fenton
Wentzville
St. Peters
Collinsville
Alton
Clayton
Festus
Glencoe
Farmington
Eureka
Edwardsville
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to St. Louis for you.

Can I find flights from Myrtle Beach to St. Louis with flexible booking policies on momondo?

momondo does allow users to show only those flights to St. Louis from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to St. Louis?

Once all potential Myrtle Beach to St. Louis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.

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