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Cheap flights from Myrtle Beach to Panama City from $137

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 7/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 8:12 am
MYR
-
ECP
3h 12m
1 stop
Delta Logo
7:50 am - 1:00 pm
ECP
-
MYR
4h 10m
1 stop
$273Delta
Wed, Jul 15 - Tue, Jul 21
Delta Logo
7:02 pm - 11:30 pm
MYR
-
ECP
5h 28m
1 stop
Delta Logo
7:35 am - 1:33 pm
ECP
-
MYR
4h 58m
1 stop
$281Delta
Mon, Aug 10 - Tue, Aug 18
Southwest Logo
7:50 am - 6:10 pm
MYR
-
ECP
11h 20m
2 stops
Southwest Logo
7:45 am - 7:10 pm
ECP
-
MYR
10h 25m
2 stops
$283Southwest
Wed, Aug 5 - Wed, Aug 12
Southwest Logo
8:15 am - 6:10 pm
MYR
-
ECP
10h 55m
2 stops
Southwest Logo
7:45 am - 4:05 pm
ECP
-
MYR
7h 20m
1 stop
$284Southwest
Wed, Aug 5 - Wed, Aug 12
American Airlines Logo
5:27 pm - 10:40 pm
MYR
-
ECP
6h 13m
1 stop
American Airlines Logo
5:48 pm - 10:38 pm
ECP
-
MYR
3h 50m
1 stop
$289American Airlines
Sat, Aug 22 - Sat, Aug 29
Southwest Logo
6:40 am - 4:35 pm
MYR
-
ECP
10h 55m
2 stops
Southwest Logo
9:10 am - 7:20 pm
ECP
-
MYR
9h 10m
2 stops
$291Southwest
Mon, Aug 10 - Tue, Aug 18
Southwest Logo
6:40 am - 4:35 pm
MYR
-
ECP
10h 55m
2 stops
Southwest Logo
7:45 am - 7:20 pm
ECP
-
MYR
10h 35m
1 stop
$292Southwest
Mon, Aug 10 - Tue, Aug 18
Southwest Logo
5:50 pm - 8:45 pm
MYR
-
ECP
3h 55m
1 stop
Southwest Logo
11:30 am - 4:05 pm
ECP
-
MYR
3h 35m
1 stop
$310Southwest
Sun, Aug 2 - Tue, Aug 4
Southwest Logo
7:55 am - 3:40 pm
MYR
-
ECP
8h 45m
2 stops
Southwest Logo
2:25 pm - 8:35 pm
ECP
-
MYR
5h 10m
1 stop
$313Southwest
Wed, Jul 15 - Tue, Jul 21
Southwest Logo
5:50 pm - 8:45 pm
MYR
-
ECP
3h 55m
1 stop
Southwest Logo
7:45 am - 7:10 pm
ECP
-
MYR
10h 25m
2 stops
$315Southwest
Sun, Aug 2 - Tue, Aug 4

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Southwest flights from Myrtle Beach to Panama City, Florida

Our best Southwest deals on Myrtle Beach to Panama City, Florida flight tickets
Southwest
Aug 5
MYR7:50 amMyrtle Beach Intl
11h 20m
2 stops
ECP6:10 pmPanama City NW Florida Beaches
Aug 12
ECP7:45 amPanama City NW Florida Beaches
10h 25m
2 stops
MYR7:10 pmMyrtle Beach Intl
$283
Southwest
Aug 5
MYR8:15 amMyrtle Beach Intl
10h 55m
2 stops
ECP6:10 pmPanama City NW Florida Beaches
Aug 12
ECP7:45 amPanama City NW Florida Beaches
7h 20m
1 stop
MYR4:05 pmMyrtle Beach Intl
$284
Southwest
Aug 10
MYR6:40 amMyrtle Beach Intl
10h 55m
2 stops
ECP4:35 pmPanama City NW Florida Beaches
Aug 18
ECP9:10 amPanama City NW Florida Beaches
9h 10m
2 stops
MYR7:20 pmMyrtle Beach Intl
$291

American Airlines flights from Myrtle Beach to Panama City, Florida

Our best American Airlines deals on Myrtle Beach to Panama City, Florida flight tickets
American Airlines
Jul 15
MYR6:10 pmMyrtle Beach Intl
6h 27m
1 stop
ECP11:37 pmPanama City NW Florida Beaches
Jul 21
ECP4:17 pmPanama City NW Florida Beaches
4h 26m
1 stop
MYR9:43 pmMyrtle Beach Intl
$273
American Airlines
Aug 22
MYR5:27 pmMyrtle Beach Intl
6h 13m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Aug 29
ECP5:48 pmPanama City NW Florida Beaches
3h 50m
1 stop
MYR10:38 pmMyrtle Beach Intl
$289
American Airlines
Jul 24
MYR6:51 amMyrtle Beach Intl
4h 36m
1 stop
ECP10:27 amPanama City NW Florida Beaches
Jul 27
ECP4:17 pmPanama City NW Florida Beaches
4h 26m
1 stop
MYR9:43 pmMyrtle Beach Intl
$347

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 20, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 7/15

6:00 am-8:12 am

1 stop3h 12m

Panama City NW Florida Beaches

Tue 7/21

7:50 am-1:00 pm

1 stop4h 10m

$273

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 8/10

7:02 pm-11:30 pm

1 stop5h 28m

Panama City NW Florida Beaches

Tue 8/18

7:35 am-1:33 pm

1 stop4h 58m

$281

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 8/5

7:50 am-6:10 pm

2 stops11h 20m

Panama City NW Florida Beaches

Wed 8/12

7:45 am-7:10 pm

2 stops10h 25m

$283

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 8/5

8:15 am-6:10 pm

2 stops10h 55m

Panama City NW Florida Beaches

Wed 8/12

7:45 am-4:05 pm

1 stop7h 20m

$284

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 8/22

5:27 pm-10:40 pm

1 stop6h 13m

Panama City NW Florida Beaches

Sat 8/29

5:48 pm-10:38 pm

1 stop3h 50m

$289

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 8/10

6:40 am-4:35 pm

2 stops10h 55m

Panama City NW Florida Beaches

Tue 8/18

9:10 am-7:20 pm

2 stops9h 10m

$291

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 8/10

6:40 am-4:35 pm

2 stops10h 55m

Panama City NW Florida Beaches

Tue 8/18

7:45 am-7:20 pm

1 stop10h 35m

$292

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sun 8/2

5:50 pm-8:45 pm

1 stop3h 55m

Panama City NW Florida Beaches

Tue 8/4

11:30 am-4:05 pm

1 stop3h 35m

$310

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 7/15

7:55 am-3:40 pm

2 stops8h 45m

Panama City NW Florida Beaches

Tue 7/21

2:25 pm-8:35 pm

1 stop5h 10m

$313

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sun 8/2

5:50 pm-8:45 pm

1 stop3h 55m

Panama City NW Florida Beaches

Tue 8/4

7:45 am-7:10 pm

2 stops10h 25m

$315

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Myrtle Beach is in October. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. The month of April is another great option to travel to Panama City, Florida, with average flight prices from Myrtle Beach averaging around $0.

When to book flights from Myrtle Beach to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City, Florida (MYR to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City, Florida

Fastest flight time

3h 12m

Direct flights

None
The fastest flight from Myrtle Beach to Panama City, Florida takes 3h 12m
There are no direct flights from Myrtle Beach to Panama City, Florida. There are no popular flight routes from Myrtle Beach to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Panama City, Florida

  • How far is Myrtle Beach Intl to Panama City NW Florida Beaches by plane?

    Myrtle Beach Intl and Panama City NW Florida Beaches are 465.6 mi apart from one another. In terms of flight time, this usually takes a little over 3h 12m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Panama City, Florida?

Best airlines flying from Myrtle Beach to Panama City, Florida

Compare and see reviews for airlines that fly from Myrtle Beach to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $207Free CancellationRating
7.8
8,420 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama City?

Finding the right flight to Panama City from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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