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Cheap flights from Myrtle Beach to Panama City from $234

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 10/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
1:10 pm - 5:35 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
5h 25m1 stop Nashville Intl
Southwest Logo
7:40 am - 1:30 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
4h 50m1 stop Nashville Intl
$234Southwest
Sat, Oct 24 - Wed, Oct 28
Southwest Logo
11:40 am - 5:35 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
6h 55m2 stops Baltimore/Washington Nashville Intl
Southwest Logo
11:30 am - 7:25 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
6h 55m1 stop Nashville Intl
$240Southwest
Sat, Oct 24 - Wed, Oct 28
Southwest Logo
11:40 am - 7:50 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
9h 10m2 stops Baltimore/Washington Dallas Love Field
Southwest Logo
7:40 am - 6:00 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
9h 20m2 stops Nashville Intl Chicago Midway
$245Southwest
Sat, Oct 24 - Wed, Oct 28
Delta Logo
6:58 pm - 11:05 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
5h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:05 pm - 11:28 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
3h 23m1 stop Atlanta Hartsfield-Jackson
$314Delta
Wed, Sep 16 - Fri, Sep 18
Delta Logo
6:58 pm - 11:05 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
5h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:05 pm - 11:28 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
3h 23m1 stop Atlanta Hartsfield-Jackson
$314Delta
Wed, Sep 16 - Fri, Sep 18
Delta Logo
6:56 pm - 9:03 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
3h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 10:07 amECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
3h 07m1 stop Atlanta Hartsfield-Jackson
$324Delta
Fri, Sep 18 - Wed, Sep 23
Delta Logo
6:58 pm - 11:05 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
5h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:05 pm - 11:28 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
3h 23m1 stop Atlanta Hartsfield-Jackson
$324Delta
Wed, Sep 16 - Fri, Sep 18
American Airlines Logo
8:08 am - 11:12 amMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
4h 04m1 stop Charlotte Douglas
American Airlines Logo
11:09 am - 5:42 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
5h 33m1 stop Charlotte Douglas
$328American Airlines
Wed, Sep 2 - Sun, Sep 6
Southwest Logo
8:15 am - 6:10 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
10h 55m2 stops Baltimore/Washington Nashville Intl
Southwest Logo
8:45 am - 1:45 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
4h 00m1 stop Nashville Intl
$333Southwest
Wed, Sep 2 - Sun, Sep 6
Southwest Logo
7:50 am - 6:15 pmMYR  Myrtle Beach Intl-ECP Panama City NW Florida Beaches
11h 25m2 stops Chicago Midway Nashville Intl
Southwest Logo
10:00 am - 5:35 pmECP  Panama City NW Florida Beaches-MYR Myrtle Beach Intl
6h 35m1 stop Chicago Midway
$334Southwest
Wed, Sep 16 - Fri, Sep 18

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American Airlines flights from Myrtle Beach to Panama City, Florida

Our best American Airlines deals on Myrtle Beach to Panama City, Florida flight tickets
American Airlines
Sep 2
MYR8:08 amMyrtle Beach Intl
4h 04m
1 stop
ECP11:12 amPanama City NW Florida Beaches
Sep 6
ECP11:09 amPanama City NW Florida Beaches
5h 33m
1 stop
MYR5:42 pmMyrtle Beach Intl
$328
American Airlines
Oct 10
MYR8:12 pmMyrtle Beach Intl
4h 41m
1 stop
ECP11:53 pmPanama City NW Florida Beaches
Oct 14
ECP7:15 amPanama City NW Florida Beaches
5h 16m
1 stop
MYR1:31 pmMyrtle Beach Intl
$414
American Airlines
Aug 22
MYR7:33 pmMyrtle Beach Intl
4h 07m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Aug 29
ECP5:48 pmPanama City NW Florida Beaches
3h 50m
1 stop
MYR10:38 pmMyrtle Beach Intl
$427

Southwest flights from Myrtle Beach to Panama City, Florida

Our best Southwest deals on Myrtle Beach to Panama City, Florida flight tickets
Southwest
Oct 24
MYR1:10 pmMyrtle Beach Intl
5h 25m
1 stop
ECP5:35 pmPanama City NW Florida Beaches
Oct 28
ECP7:40 amPanama City NW Florida Beaches
4h 50m
1 stop
MYR1:30 pmMyrtle Beach Intl
$234
Southwest
Oct 24
MYR11:40 amMyrtle Beach Intl
6h 55m
2 stops
ECP5:35 pmPanama City NW Florida Beaches
Oct 28
ECP11:30 amPanama City NW Florida Beaches
6h 55m
1 stop
MYR7:25 pmMyrtle Beach Intl
$240
Southwest
Oct 24
MYR11:40 amMyrtle Beach Intl
9h 10m
2 stops
ECP7:50 pmPanama City NW Florida Beaches
Oct 28
ECP7:40 amPanama City NW Florida Beaches
9h 20m
2 stops
MYR6:00 pmMyrtle Beach Intl
$245

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Sat 10/24

1:10 pm-5:35 pm

1 stop5h 25m

Panama City NW Florida Beaches

Wed 10/28

7:40 am-1:30 pm

1 stop4h 50m

$234

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Sat 10/24

11:40 am-5:35 pm

2 stops6h 55m

Panama City NW Florida Beaches

Wed 10/28

11:30 am-7:25 pm

1 stop6h 55m

$240

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Sat 10/24

11:40 am-7:50 pm

2 stops9h 10m

Panama City NW Florida Beaches

Wed 10/28

7:40 am-6:00 pm

2 stops9h 20m

$245

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Wed 9/16

6:58 pm-11:05 pm

1 stop5h 07m

Panama City NW Florida Beaches

Fri 9/18

7:05 pm-11:28 pm

1 stop3h 23m

$314

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Wed 9/16

6:58 pm-11:05 pm

1 stop5h 07m

Panama City NW Florida Beaches

Fri 9/18

7:05 pm-11:28 pm

1 stop3h 23m

$314
Quickest round-trip

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Fri 9/18

6:56 pm-9:03 pm

1 stop3h 07m

Panama City NW Florida Beaches

Wed 9/23

6:00 am-10:07 am

1 stop3h 07m

$324

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Wed 9/16

6:58 pm-11:05 pm

1 stop5h 07m

Panama City NW Florida Beaches

Fri 9/18

7:05 pm-11:28 pm

1 stop3h 23m

$324

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Wed 9/2

8:08 am-11:12 am

1 stop4h 04m

Panama City NW Florida Beaches

Sun 9/6

11:09 am-5:42 pm

1 stop5h 33m

$328

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Wed 9/2

8:15 am-6:10 pm

2 stops10h 55m

Panama City NW Florida Beaches

Sun 9/6

8:45 am-1:45 pm

1 stop4h 00m

$333

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Wed 9/16

7:50 am-6:15 pm

2 stops11h 25m

Panama City NW Florida Beaches

Fri 9/18

10:00 am-5:35 pm

1 stop6h 35m

$334

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Myrtle Beach is in April. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. The month of June is another great option to travel to Panama City, Florida, with average flight prices from Myrtle Beach averaging around $286.

When to book flights from Myrtle Beach to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City, Florida (MYR to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City, Florida

Fastest flight time

3h 31m

Direct flights

None
The fastest flight from Myrtle Beach to Panama City, Florida takes 3h 31m
There are no direct flights from Myrtle Beach to Panama City, Florida. There are no popular flight routes from Myrtle Beach to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Panama City, Florida

  • How far is Myrtle Beach Intl to Panama City NW Florida Beaches by plane?

    Myrtle Beach Intl and Panama City NW Florida Beaches are 465.6 mi apart from one another. In terms of flight time, this usually takes a little over 3h 31m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Panama City, Florida?

Best airlines flying from Myrtle Beach to Panama City, Florida

Compare and see reviews for airlines that fly from Myrtle Beach to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $286Free CancellationRating
7.8
8,497 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama City?

Finding the right flight to Panama City from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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