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Cheap flights from Myrtle Beach to Panama City from $184

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 4/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
10:33 am - 12:45 pmMYR-ECP
3h 12m1 stop
Delta Logo
5:14 pm - 11:43 pmECP-MYR
5h 29m1 stop
$249Delta
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Tue, Jan 6 - Sat, Jan 10
American Airlines Logo
6:00 am - 9:55 amMYR-ECP
4h 55m1 stop
American Airlines Logo
4:30 pm - 10:34 pmECP-MYR
5h 04m1 stop
$269American Airlines
Find Deal
Mon, Feb 23 - Thu, Feb 26
Delta Logo
11:09 am - 3:24 pmMYR-ECP
5h 15m1 stop
Delta Logo
5:14 pm - 11:43 pmECP-MYR
5h 29m1 stop
$288Delta
Find Deal
Sat, Jan 3 - Sat, Jan 10
American Airlines Logo
5:38 pm - 10:37 pmMYR-ECP
5h 59m1 stop
American Airlines Logo
7:19 am - 2:28 pmECP-MYR
6h 09m1 stop
$299American Airlines
Find Deal
Tue, Feb 24 - Fri, Feb 27
Delta Logo
11:09 am - 1:19 pmMYR-ECP
3h 10m1 stop
Delta Logo
5:14 pm - 11:43 pmECP-MYR
5h 29m1 stop
$308Delta
Find Deal
Thu, Jan 1 - Sat, Jan 10
American Airlines Logo
6:00 am - 10:37 amMYR-ECP
5h 37m1 stop
American Airlines Logo
12:03 pm - 4:59 pmECP-MYR
3h 56m1 stop
$309American Airlines
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Mon, Jan 5 - Wed, Jan 14
Delta Logo
10:23 am - 12:45 pmMYR-ECP
3h 22m1 stop
Delta Logo
7:00 am - 1:32 pmECP-MYR
5h 32m1 stop
$317Delta
Find Deal
Tue, Mar 17 - Wed, Mar 18
American Airlines Logo
7:56 pm - 11:52 pmMYR-ECP
4h 56m1 stop
American Airlines Logo
7:19 am - 12:13 pmECP-MYR
3h 54m1 stop
$318American Airlines
Find Deal
Mon, Feb 23 - Fri, Mar 27
Southwest Logo
11:05 am - 6:10 pmMYR-ECP
8h 05m1 stop
Southwest Logo
5:50 pm - 9:50 amECP-MYR
15h 00m2 stops
$324Southwest
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Tue, Feb 24 - Fri, Feb 27
Delta Logo
11:09 am - 3:24 pmMYR-ECP
5h 15m1 stop
Delta Logo
7:20 am - 1:30 pmECP-MYR
5h 10m1 stop
$327Delta
Find Deal
Sat, Jan 3 - Sun, Jan 11

Delta flights from Myrtle Beach to Panama City, Florida

Our best Delta deals on Myrtle Beach to Panama City, Florida flight tickets
Delta
Jan 6
MYR10:33 amMyrtle Beach Intl
3h 12m
1 stop
ECP12:45 pmPanama City NW Florida Beaches
Jan 10
ECP5:14 pmPanama City NW Florida Beaches
5h 29m
1 stop
MYR11:43 pmMyrtle Beach Intl
$249
Find similar
Delta
Jan 3
MYR11:09 amMyrtle Beach Intl
5h 15m
1 stop
ECP3:24 pmPanama City NW Florida Beaches
Jan 8
ECP10:01 amPanama City NW Florida Beaches
4h 10m
1 stop
MYR3:11 pmMyrtle Beach Intl
$288
Find similar
Delta
Jan 1
MYR11:09 amMyrtle Beach Intl
3h 10m
1 stop
ECP1:19 pmPanama City NW Florida Beaches
Jan 10
ECP5:14 pmPanama City NW Florida Beaches
5h 29m
1 stop
MYR11:43 pmMyrtle Beach Intl
$308
Find similar

American Airlines flights from Myrtle Beach to Panama City, Florida

Our best American Airlines deals on Myrtle Beach to Panama City, Florida flight tickets
American Airlines
Feb 23
MYR6:00 amMyrtle Beach Intl
4h 55m
1 stop
ECP9:55 amPanama City NW Florida Beaches
Feb 26
ECP4:30 pmPanama City NW Florida Beaches
5h 04m
1 stop
MYR10:34 pmMyrtle Beach Intl
$269
Find similar
American Airlines
Feb 24
MYR5:38 pmMyrtle Beach Intl
5h 59m
1 stop
ECP10:37 pmPanama City NW Florida Beaches
Feb 27
ECP7:19 amPanama City NW Florida Beaches
6h 09m
1 stop
MYR2:28 pmMyrtle Beach Intl
$299
Find similar
American Airlines
Jan 5
MYR6:00 amMyrtle Beach Intl
5h 37m
1 stop
ECP10:37 amPanama City NW Florida Beaches
Jan 14
ECP12:03 pmPanama City NW Florida Beaches
3h 56m
1 stop
MYR4:59 pmMyrtle Beach Intl
$309
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 25, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 1/6

10:33 am-12:45 pm

1 stop3h 12m

Panama City NW Florida Beaches

Sat 1/10

5:14 pm-11:43 pm

1 stop5h 29m

$249

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 2/23

6:00 am-9:55 am

1 stop4h 55m

Panama City NW Florida Beaches

Thu 2/26

4:30 pm-10:34 pm

1 stop5h 04m

$269

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 1/3

11:09 am-3:24 pm

1 stop5h 15m

Panama City NW Florida Beaches

Sat 1/10

5:14 pm-11:43 pm

1 stop5h 29m

$288

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 2/24

5:38 pm-10:37 pm

1 stop5h 59m

Panama City NW Florida Beaches

Fri 2/27

7:19 am-2:28 pm

1 stop6h 09m

$299

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 1/1

11:09 am-1:19 pm

1 stop3h 10m

Panama City NW Florida Beaches

Sat 1/10

5:14 pm-11:43 pm

1 stop5h 29m

$308

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 1/5

6:00 am-10:37 am

1 stop5h 37m

Panama City NW Florida Beaches

Wed 1/14

12:03 pm-4:59 pm

1 stop3h 56m

$309

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 3/17

10:23 am-12:45 pm

1 stop3h 22m

Panama City NW Florida Beaches

Wed 3/18

7:00 am-1:32 pm

1 stop5h 32m

$317

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 2/23

7:56 pm-11:52 pm

1 stop4h 56m

Panama City NW Florida Beaches

Fri 3/27

7:19 am-12:13 pm

1 stop3h 54m

$318

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 2/24

11:05 am-6:10 pm

1 stop8h 05m

Panama City NW Florida Beaches

Fri 2/27

5:50 pm-9:50 am

2 stops15h 00m

$324

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 1/3

11:09 am-3:24 pm

1 stop5h 15m

Panama City NW Florida Beaches

Sun 1/11

7:20 am-1:30 pm

1 stop5h 10m

$327

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Wednesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $198. On the other hand, Sunday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $456.

When to book flights from Myrtle Beach to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City, Florida (MYR to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City, Florida

Fastest flight time

3h 22m

Direct flights

None
The fastest flight from Myrtle Beach to Panama City, Florida takes 3h 22m
There are no direct flights from Myrtle Beach to Panama City, Florida. There are no popular flight routes from Myrtle Beach to Panama City, Florida.
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  • How far is Myrtle Beach Intl to Panama City NW Florida Beaches by plane?

    Myrtle Beach Intl and Panama City NW Florida Beaches are 465.6 mi apart from one another. In terms of flight time, this usually takes a little over 3h 10m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Panama City, Florida?

Best airlines flying from Myrtle Beach to Panama City, Florida

Compare and see reviews for airlines that fly from Myrtle Beach to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $207Free CancellationRating
7.9
7,999 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama City?

Finding the right flight to Panama City from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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