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Cheap flights from Myrtle Beach to Panama City from $208

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 9/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Delta Logo
6:55 pm - 11:03 pmMYR-ECP
5h 08m1 stop
Delta Logo
6:54 pm - 11:49 pmECP-MYR
3h 55m1 stop
$208Delta
Find Deal
Fri, Sep 12 - Mon, Sep 15
American Airlines Logo
5:59 pm - 11:44 pmMYR-ECP
6h 45m1 stop
American Airlines Logo
2:40 pm - 9:50 pmECP-MYR
6h 10m1 stop
$263American Airlines
Find Deal
Fri, Oct 17 - Mon, Oct 20
Delta Logo
6:55 pm - 11:03 pmMYR-ECP
5h 08m1 stop
Delta Logo
6:54 pm - 11:49 pmECP-MYR
3h 55m1 stop
$267Delta
Find Deal
Thu, Sep 11 - Sun, Sep 14
Southwest Logo
6:00 pm - 9:00 pmMYR-ECP
4h 00m1 stop
Southwest Logo
7:25 am - 5:10 pmECP-MYR
8h 45m2 stops
$298Southwest
Find Deal
Fri, Sep 12 - Mon, Sep 15
Southwest Logo
7:00 am - 4:55 pmMYR-ECP
10h 55m2 stops
Southwest Logo
6:35 am - 5:10 pmECP-MYR
9h 35m2 stops
$377Southwest
Find Deal
Fri, Sep 12 - Mon, Sep 15
Southwest Logo
10:25 am - 3:35 pmMYR-ECP
6h 10m1 stop
Southwest Logo
7:15 am - 2:15 pmECP-MYR
6h 00m1 stop
$389Southwest
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Mon, Dec 29 - Thu, Jan 1
Southwest Logo
7:00 am - 3:35 pmMYR-ECP
9h 35m2 stops
Southwest Logo
7:15 am - 2:15 pmECP-MYR
6h 00m1 stop
$394Southwest
Find Deal
Mon, Dec 29 - Thu, Jan 1
Southwest Logo
12:45 pm - 10:35 pmMYR-ECP
10h 50m2 stops
Southwest Logo
2:55 pm - 10:20 pmECP-MYR
6h 25m1 stop
$465Southwest
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Fri, Oct 17 - Mon, Oct 20
United Airlines Logo
5:57 pm - 1:05 pmMYR-ECP
20h 08m2 stops
United Airlines Logo
5:08 pm - 2:42 pmECP-MYR
20h 34m2 stops
$773United Airlines
Find Deal
Fri, Oct 17 - Mon, Oct 20
United Airlines Logo
4:45 pm - 9:54 amMYR-ECP
42h 09m2 stops
United Airlines Logo
6:30 am - 2:42 pmECP-MYR
31h 12m2 stops
$1,947United Airlines
Find Deal
Thu, Aug 28 - Mon, Sep 1

Delta flights from Myrtle Beach to Panama City, Florida

Our best Delta deals on Myrtle Beach to Panama City, Florida flight tickets
Delta
Sep 12
MYR6:55 pmMyrtle Beach Intl
5h 08m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Sep 15
ECP6:54 pmPanama City NW Florida Beaches
3h 55m
1 stop
MYR11:49 pmMyrtle Beach Intl
$208
Find similar
Delta
Sep 11
MYR6:55 pmMyrtle Beach Intl
5h 08m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Sep 14
ECP6:54 pmPanama City NW Florida Beaches
3h 55m
1 stop
MYR11:49 pmMyrtle Beach Intl
$267
Find similar
Delta
Aug 22
MYR6:00 amMyrtle Beach Intl
3h 19m
1 stop
ECP8:19 amPanama City NW Florida Beaches
Aug 24
ECP6:54 pmPanama City NW Florida Beaches
3h 55m
1 stop
MYR11:49 pmMyrtle Beach Intl
$507
Find similar

American Airlines flights from Myrtle Beach to Panama City, Florida

Our best American Airlines deals on Myrtle Beach to Panama City, Florida flight tickets
American Airlines
Oct 17
MYR5:59 pmMyrtle Beach Intl
6h 45m
1 stop
ECP11:44 pmPanama City NW Florida Beaches
Oct 20
ECP2:40 pmPanama City NW Florida Beaches
6h 10m
1 stop
MYR9:50 pmMyrtle Beach Intl
$263
Find similar
American Airlines
Aug 28
MYR8:20 pmMyrtle Beach Intl
4h 21m
1 stop
ECP11:41 pmPanama City NW Florida Beaches
Sep 1
ECP7:06 pmPanama City NW Florida Beaches
3h 36m
1 stop
MYR11:42 pmMyrtle Beach Intl
$527
Find similar
American Airlines
Oct 17
MYR7:26 pmMyrtle Beach Intl
18h 46m
1 stop
ECP1:12 pmPanama City NW Florida Beaches
Oct 20
ECP5:30 amPanama City NW Florida Beaches
11h 23m
2 stops
MYR5:53 pmMyrtle Beach Intl
$606
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momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 9/12

6:55 pm-11:03 pm

1 stop5h 08m

Panama City NW Florida Beaches

Mon 9/15

6:54 pm-11:49 pm

1 stop3h 55m

$208

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 10/17

5:59 pm-11:44 pm

1 stop6h 45m

Panama City NW Florida Beaches

Mon 10/20

2:40 pm-9:50 pm

1 stop6h 10m

$263

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 9/11

6:55 pm-11:03 pm

1 stop5h 08m

Panama City NW Florida Beaches

Sun 9/14

6:54 pm-11:49 pm

1 stop3h 55m

$267

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 9/12

6:00 pm-9:00 pm

1 stop4h 00m

Panama City NW Florida Beaches

Mon 9/15

7:25 am-5:10 pm

2 stops8h 45m

$298

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 9/12

7:00 am-4:55 pm

2 stops10h 55m

Panama City NW Florida Beaches

Mon 9/15

6:35 am-5:10 pm

2 stops9h 35m

$377

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 12/29

10:25 am-3:35 pm

1 stop6h 10m

Panama City NW Florida Beaches

Thu 1/1

7:15 am-2:15 pm

1 stop6h 00m

$389

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 12/29

7:00 am-3:35 pm

2 stops9h 35m

Panama City NW Florida Beaches

Thu 1/1

7:15 am-2:15 pm

1 stop6h 00m

$394

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 10/17

12:45 pm-10:35 pm

2 stops10h 50m

Panama City NW Florida Beaches

Mon 10/20

2:55 pm-10:20 pm

1 stop6h 25m

$465

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 10/17

5:57 pm-1:05 pm

2 stops20h 08m

Panama City NW Florida Beaches

Mon 10/20

5:08 pm-2:42 pm

2 stops20h 34m

$773

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 8/28

4:45 pm-9:54 am

2 stops42h 09m

Panama City NW Florida Beaches

Mon 9/1

6:30 am-2:42 pm

2 stops31h 12m

$1,947

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Wednesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $198. On the other hand, Sunday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $456.

When to book flights from Myrtle Beach to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City, Florida (MYR to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City, Florida

Best Price Found

$208

Fastest flight time

4h 00m

Direct flights

None

Airports in Panama City, Florida

1 airport
The best flight deal from Myrtle Beach to Panama City, Florida found on momondo in the last 72 hours is $208
The fastest flight from Myrtle Beach to Panama City, Florida takes 4h 00m
There are no direct flights from Myrtle Beach to Panama City, Florida. Popular non-direct route for this connection is Myrtle Beach Intl Airport - Panama City NW Florida Beaches Airport.
There is 1 airport near Panama City, Florida: Panama City NW Florida Beaches (ECP)
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  • How far is Myrtle Beach Intl to Panama City NW Florida Beaches by plane?

    Myrtle Beach Intl and Panama City NW Florida Beaches are 465.6 mi apart from one another. In terms of flight time, this usually takes a little over 4h 00m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Panama City, Florida?

Best airlines flying from Myrtle Beach to Panama City, Florida

Compare and see reviews for airlines that fly from Myrtle Beach to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $102Free CancellationRating
8.0
7,980 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama City?

Finding the right flight to Panama City from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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