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Cheap flights from Myrtle Beach to Panama City from $146

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Myrtle Beach to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
1:00 pm - 7:00 pm
MYR
-
ECP
7h 00m
1 stop
Southwest Logo
7:15 am - 1:30 pm
ECP
-
MYR
5h 15m
1 stop
$280Southwest
Σαβ, Μαϊ 2 - Τρι, Μαϊ 5
Southwest Logo
1:00 pm - 7:00 pm
MYR
-
ECP
7h 00m
1 stop
Southwest Logo
7:15 am - 3:25 pm
ECP
-
MYR
7h 10m
2 stops
$285Southwest
Σαβ, Μαϊ 2 - Τρι, Μαϊ 5
Delta Logo
6:00 am - 8:35 am
MYR
-
ECP
3h 35m
1 stop
Delta Logo
9:17 am - 3:21 pm
ECP
-
MYR
5h 04m
1 stop
$291Delta
Τρι, Μαϊ 5 - Τρι, Μαϊ 12
Southwest Logo
4:05 pm - 6:55 pm
MYR
-
ECP
3h 50m
1 stop
Southwest Logo
7:55 am - 8:30 pm
ECP
-
MYR
11h 35m
2 stops
$308Southwest
Τρι, Μαϊ 5 - Τρι, Μαϊ 12
Southwest Logo
7:35 am - 8:25 pm
MYR
-
ECP
13h 50m
2 stops
Southwest Logo
7:55 am - 8:30 pm
ECP
-
MYR
11h 35m
2 stops
$319Southwest
Τρι, Μαϊ 5 - Τρι, Μαϊ 12
Southwest Logo
7:10 am - 6:15 pm
MYR
-
ECP
12h 05m
2 stops
Southwest Logo
9:00 am - 8:30 pm
ECP
-
MYR
10h 30m
2 stops
$325Southwest
Σαβ, Μαϊ 2 - Τρι, Μαϊ 5
Delta Logo
6:54 pm - 11:04 pm
MYR
-
ECP
5h 10m
1 stop
Delta Logo
5:10 pm - 12:14 am
ECP
-
MYR
6h 04m
1 stop
$329Delta
Τετ, Απρ 8 - Τετ, Απρ 15
Southwest Logo
11:15 am - 8:45 pm
MYR
-
ECP
10h 30m
2 stops
Southwest Logo
12:05 pm - 5:35 pm
ECP
-
MYR
4h 30m
1 stop
$366Southwest
Τετ, Απρ 8 - Τετ, Απρ 15
American Airlines Logo
8:41 pm - 11:40 pm
MYR
-
ECP
3h 59m
1 stop
American Airlines Logo
6:45 pm - 11:50 pm
ECP
-
MYR
4h 05m
1 stop
$368American Airlines
Κυρ, Ιουν 21 - Σαβ, Ιουν 27
Southwest Logo
11:15 am - 8:45 pm
MYR
-
ECP
10h 30m
2 stops
Southwest Logo
7:55 am - 8:30 pm
ECP
-
MYR
11h 35m
2 stops
$379Southwest
Τετ, Απρ 8 - Τετ, Απρ 15

Delta flights from Myrtle Beach to Panama City, Florida

Our best Delta deals on Myrtle Beach to Panama City, Florida flight tickets
Delta
May 5
MYR6:00 amMyrtle Beach Intl
3h 35m
1 stop
ECP8:35 amPanama City NW Florida Beaches
May 12
ECP9:17 amPanama City NW Florida Beaches
5h 04m
1 stop
MYR3:21 pmMyrtle Beach Intl
$291
Delta
Apr 8
MYR6:54 pmMyrtle Beach Intl
5h 10m
1 stop
ECP11:04 pmPanama City NW Florida Beaches
Apr 15
ECP5:10 pmPanama City NW Florida Beaches
6h 04m
1 stop
MYR12:14 amMyrtle Beach Intl
$329
Delta
Mar 26
MYR6:54 pmMyrtle Beach Intl
3h 28m
1 stop
ECP9:22 pmPanama City NW Florida Beaches
Mar 30
ECP6:43 pmPanama City NW Florida Beaches
4h 21m
1 stop
MYR12:04 amMyrtle Beach Intl
$413

Southwest flights from Myrtle Beach to Panama City, Florida

Our best Southwest deals on Myrtle Beach to Panama City, Florida flight tickets
Southwest
May 2
MYR1:00 pmMyrtle Beach Intl
7h 00m
1 stop
ECP7:00 pmPanama City NW Florida Beaches
May 5
ECP7:15 amPanama City NW Florida Beaches
5h 15m
1 stop
MYR1:30 pmMyrtle Beach Intl
$280
Southwest
May 2
MYR1:00 pmMyrtle Beach Intl
7h 00m
1 stop
ECP7:00 pmPanama City NW Florida Beaches
May 5
ECP7:15 amPanama City NW Florida Beaches
7h 10m
2 stops
MYR3:25 pmMyrtle Beach Intl
$285
Southwest
May 5
MYR4:05 pmMyrtle Beach Intl
3h 50m
1 stop
ECP6:55 pmPanama City NW Florida Beaches
May 12
ECP7:55 amPanama City NW Florida Beaches
11h 35m
2 stops
MYR8:30 pmMyrtle Beach Intl
$308

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Μάρτιος 3, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Σαβ 5/2

1:00 pm-7:00 pm

1 stop7h 00m

Panama City NW Florida Beaches

Τρι 5/5

7:15 am-1:30 pm

1 stop5h 15m

$280

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Σαβ 5/2

1:00 pm-7:00 pm

1 stop7h 00m

Panama City NW Florida Beaches

Τρι 5/5

7:15 am-3:25 pm

2 stops7h 10m

$285

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Τρι 5/5

6:00 am-8:35 am

1 stop3h 35m

Panama City NW Florida Beaches

Τρι 5/12

9:17 am-3:21 pm

1 stop5h 04m

$291

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Τρι 5/5

4:05 pm-6:55 pm

1 stop3h 50m

Panama City NW Florida Beaches

Τρι 5/12

7:55 am-8:30 pm

2 stops11h 35m

$308

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Τρι 5/5

7:35 am-8:25 pm

2 stops13h 50m

Panama City NW Florida Beaches

Τρι 5/12

7:55 am-8:30 pm

2 stops11h 35m

$319

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Σαβ 5/2

7:10 am-6:15 pm

2 stops12h 05m

Panama City NW Florida Beaches

Τρι 5/5

9:00 am-8:30 pm

2 stops10h 30m

$325

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Τετ 4/8

6:54 pm-11:04 pm

1 stop5h 10m

Panama City NW Florida Beaches

Τετ 4/15

5:10 pm-12:14 am

1 stop6h 04m

$329

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Τετ 4/8

11:15 am-8:45 pm

2 stops10h 30m

Panama City NW Florida Beaches

Τετ 4/15

12:05 pm-5:35 pm

1 stop4h 30m

$366

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Κυρ 6/21

8:41 pm-11:40 pm

1 stop3h 59m

Panama City NW Florida Beaches

Σαβ 6/27

6:45 pm-11:50 pm

1 stop4h 05m

$368

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Τετ 4/8

11:15 am-8:45 pm

2 stops10h 30m

Panama City NW Florida Beaches

Τετ 4/15

7:55 am-8:30 pm

2 stops11h 35m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Myrtle Beach Intl to Panama City NW Florida Beaches?

Delta, Southwest, and United Airlines are the most popular carriers operating from Myrtle Beach Intl to Panama City NW Florida Beaches

What airlines fly to Panama City, Florida?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to Panama City, Florida from Myrtle Beach according to our data. Delta is the first choice among our users, with 58% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 3 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

When to book flights from Myrtle Beach to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City, Florida (MYR to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City, Florida

Fastest flight time

3h 28m

Direct flights

None
The fastest flight from Myrtle Beach to Panama City, Florida takes 3h 28m
There are no direct flights from Myrtle Beach to Panama City, Florida. There are no popular flight routes from Myrtle Beach to Panama City, Florida.
Search flight deals

  • How far is Myrtle Beach Intl to Panama City NW Florida Beaches by plane?

    Myrtle Beach Intl and Panama City NW Florida Beaches are 465.6 mi apart from one another. In terms of flight time, this usually takes a little over 3h 28m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Panama City, Florida?

Best airlines flying from Myrtle Beach to Panama City, Florida

Compare and see reviews for airlines that fly from Myrtle Beach to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $207Free CancellationRating
7.9
8,245 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama City?

Finding the right flight to Panama City from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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