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Cheap flights from Myrtle Beach to Minneapolis from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Minneapolis departing on 11/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Minneapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 1:10 pmMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
7h 10m1 stop Charlotte Douglas
American Airlines Logo
10:48 am - 4:23 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
4h 35m1 stop Charlotte Douglas
$217American Airlines
Thu, Nov 26 - Wed, Dec 2
Southwest Logo
5:00 pm - 10:45 pmMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
6h 45m1 stop Nashville Intl
Southwest Logo
1:40 pm - 7:25 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
4h 45m1 stop Nashville Intl
$218Southwest
Wed, Oct 14 - Wed, Oct 21
Southwest Logo
2:10 pm - 10:45 pmMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
9h 35m2 stops Baltimore/Washington Nashville Intl
Southwest Logo
1:40 pm - 7:25 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
4h 45m1 stop Nashville Intl
$223Southwest
Wed, Oct 14 - Wed, Oct 21
Southwest Logo
7:50 pm - 12:10 amMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
5h 20m1 stop Baltimore/Washington
Southwest Logo
2:55 pm - 9:25 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
5h 30m1 stop Baltimore/Washington
$245Southwest
Fri, Oct 16 - Mon, Oct 19
American Airlines Logo
6:12 am - 10:08 amMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
4h 56m1 stop Charlotte Douglas
American Airlines Logo
5:00 pm - 10:29 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
4h 29m1 stop Charlotte Douglas
$268American Airlines
Mon, Dec 7 - Mon, Dec 14
American Airlines Logo
11:57 am - 4:41 pmMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
5h 44m1 stop Washington, D.C. Reagan-National
American Airlines Logo
10:48 am - 4:23 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
4h 35m1 stop Charlotte Douglas
$268American Airlines
Mon, Dec 7 - Mon, Dec 14
Multiple Airlines Logo
5:58 pm - 2:10 pmMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
21h 12m1 stop Tampa
Multiple Airlines Logo
2:36 pm - 12:14 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
20h 38m2 stops Denver Intl Tampa
$306Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
5:58 pm - 2:10 pmMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
21h 12m1 stop Tampa
Multiple Airlines Logo
2:36 pm - 11:44 amMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
20h 08m2 stops Denver Intl Tampa
$311Multiple Airlines
Wed, Oct 14 - Tue, Oct 20
Delta Logo
10:55 am - 5:21 pmMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
7h 26m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:15 am - 5:55 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
9h 40m2 stops Cincinnati Cinci./N. Kentucky Atlanta Hartsfield-Jackson
$334Delta
Mon, Dec 21 - Fri, Dec 25
Delta Logo
2:18 pm - 8:57 pmMYR  Myrtle Beach Intl-MSP Minneapolis St Paul
7h 39m2 stops Atlanta Hartsfield-Jackson Cincinnati Cinci./N. Kentucky
Delta Logo
4:28 pm - 11:09 pmMSP  Minneapolis St Paul-MYR Myrtle Beach Intl
5h 41m1 stop Atlanta Hartsfield-Jackson
$334Delta
Mon, Dec 7 - Mon, Dec 14

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American Airlines flights from Myrtle Beach to Minneapolis

Our best American Airlines deals on Myrtle Beach to Minneapolis flight tickets
American Airlines
Nov 26
MYR7:00 amMyrtle Beach Intl
7h 10m
1 stop
MSP1:10 pmMinneapolis St Paul
Dec 2
MSP10:48 amMinneapolis St Paul
4h 35m
1 stop
MYR4:23 pmMyrtle Beach Intl
$217
American Airlines
Dec 7
MYR6:12 amMyrtle Beach Intl
4h 56m
1 stop
MSP10:08 amMinneapolis St Paul
Dec 14
MSP5:00 pmMinneapolis St Paul
4h 29m
1 stop
MYR10:29 pmMyrtle Beach Intl
$268
American Airlines
Sep 2
MYR5:15 pmMyrtle Beach Intl
4h 51m
1 stop
MSP9:06 pmMinneapolis St Paul
Sep 9
MSP3:01 pmMinneapolis St Paul
5h 07m
1 stop
MYR9:08 pmMyrtle Beach Intl
$273

Southwest flights from Myrtle Beach to Minneapolis

Our best Southwest deals on Myrtle Beach to Minneapolis flight tickets
Southwest
Oct 14
MYR5:00 pmMyrtle Beach Intl
6h 45m
1 stop
MSP10:45 pmMinneapolis St Paul
Oct 21
MSP1:40 pmMinneapolis St Paul
4h 45m
1 stop
MYR7:25 pmMyrtle Beach Intl
$218
Southwest
Oct 14
MYR2:10 pmMyrtle Beach Intl
9h 35m
2 stops
MSP10:45 pmMinneapolis St Paul
Oct 21
MSP1:40 pmMinneapolis St Paul
4h 45m
1 stop
MYR7:25 pmMyrtle Beach Intl
$223
Southwest
Oct 16
MYR7:50 pmMyrtle Beach Intl
5h 20m
1 stop
MSP12:10 amMinneapolis St Paul
Oct 19
MSP2:55 pmMinneapolis St Paul
5h 30m
1 stop
MYR9:25 pmMyrtle Beach Intl
$245

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Minneapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Minneapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Thu 11/26

7:00 am-1:10 pm

1 stop7h 10m

Minneapolis St Paul

Wed 12/2

10:48 am-4:23 pm

1 stop4h 35m

$217

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Wed 10/14

5:00 pm-10:45 pm

1 stop6h 45m

Minneapolis St Paul

Wed 10/21

1:40 pm-7:25 pm

1 stop4h 45m

$218

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Wed 10/14

2:10 pm-10:45 pm

2 stops9h 35m

Minneapolis St Paul

Wed 10/21

1:40 pm-7:25 pm

1 stop4h 45m

$223

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Fri 10/16

7:50 pm-12:10 am

1 stop5h 20m

Minneapolis St Paul

Mon 10/19

2:55 pm-9:25 pm

1 stop5h 30m

$245
Quickest round-trip

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Mon 12/7

6:12 am-10:08 am

1 stop4h 56m

Minneapolis St Paul

Mon 12/14

5:00 pm-10:29 pm

1 stop4h 29m

$268

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Mon 12/7

11:57 am-4:41 pm

1 stop5h 44m

Minneapolis St Paul

Mon 12/14

10:48 am-4:23 pm

1 stop4h 35m

$268

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Wed 10/14

5:58 pm-2:10 pm

1 stop21h 12m

Minneapolis St Paul

Wed 10/21

2:36 pm-12:14 pm

2 stops20h 38m

$306

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Wed 10/14

5:58 pm-2:10 pm

1 stop21h 12m

Minneapolis St Paul

Tue 10/20

2:36 pm-11:44 am

2 stops20h 08m

$311

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Mon 12/21

10:55 am-5:21 pm

1 stop7h 26m

Minneapolis St Paul

Fri 12/25

7:15 am-5:55 pm

2 stops9h 40m

$334

Myrtle BeachMinneapolis

MYR Myrtle Beach Intl - MSP Minneapolis St Paul

MYRMSP

Myrtle Beach Intl

Mon 12/7

2:18 pm-8:57 pm

2 stops7h 39m

Minneapolis St Paul

Mon 12/14

4:28 pm-11:09 pm

1 stop5h 41m

$334

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Minneapolis from

How to get the cheapest flight ticket from Myrtle Beach to Minneapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Minneapolis?

Prices are currently low for flights on this route.

Typical prices usually range from $318 to $588.
The lowest price recently found on this route was $217.

What is the cheapest month to fly to Minneapolis?

The month of May is, on average, the cheapest month to fly to Minneapolis from Myrtle Beach, with most prices found around $306. If you aren’t able to travel during the month of May, then book flights to Minneapolis from Myrtle Beach during September instead. Flights to Minneapolis in September, while not as cheap as those in May, still average around $318.

What is the cheapest day to depart on your flight to Minneapolis?

The cheapest day to depart from Myrtle Beach to Minneapolis is on a Monday when prices can be found for as low as $178. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Minneapolis on Sunday is $642.

What is the cheapest time of day to depart on your flight to Minneapolis?

Our most recent data shows that the best time of day to fly to Minneapolis is in the morning. Flights from Myrtle Beach to Minneapolis during this time can be as low as $143. Try not to purchase tickets in the afternoon because they tend to be around $462. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Myrtle Beach Intl to Minneapolis St Paul flight route?

Fly from Myrtle Beach Intl to Minneapolis St Paul for the best Myrtle Beach Intl - Minneapolis St Paul flight prices

What cabin class options are available on Myrtle Beach to Minneapolis flights?

There are 4 cabin classes available to choose from on Myrtle Beach to Minneapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Minneapolis flights?

You could potentially save up to 1% on your flight if you consider stops on a Myrtle Beach to Minneapolis flight.

How have Myrtle Beach to Minneapolis flight prices changed over time?

As of August 2026, prices for Myrtle Beach to Minneapolis flights are approximately 101% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Minneapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Minneapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Minneapolis (MYR to MSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Minneapolis

Best Price Found

$563

Fastest flight time

4h 40m

Direct flights

None
The best one-way flight to Minneapolis from Myrtle Beach in the past 72 hours is $563. The best round-trip flight deal from Myrtle Beach to Minneapolis found on momondo in the last 72 hours is $864.
The fastest flight from Myrtle Beach to Minneapolis takes 4h 40m
There are no direct flights from Myrtle Beach to Minneapolis. Popular non-direct route for this connection is Myrtle Beach Intl Airport - Minneapolis St Paul Airport.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Minneapolis

  • How far is Myrtle Beach Intl to Minneapolis St Paul by plane?

    Minneapolis St Paul is 1091.0 mi away from Myrtle Beach Intl. A reasonable flight in good conditions will take 4h 40m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Minneapolis St Paul Airport?

    Prices for flights from Myrtle Beach Intl Airport to Minneapolis St Paul Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Minneapolis St Paul Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Minneapolis St Paul Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Minneapolis St Paul Airport.

  • What documentation or ID do you need to fly to Minneapolis St Paul Airport?

    The travel and health documents required for your trip to Minneapolis St Paul Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Minneapolis St Paul Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Myrtle Beach to Minneapolis?

  • What is the most popular airline from Myrtle Beach to Minneapolis?

Best airlines flying from Myrtle Beach to Minneapolis

Compare and see reviews for airlines that fly from Myrtle Beach to Minneapolis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $250Free CancellationRating
7.8
8,502 reviews
Search Delta flights
American AirlinesPriceFrom $250Free CancellationRating
7.1
11,927 reviews
Search American Airlines flights
SouthwestPriceFrom $289Free CancellationRating
8.0
4,220 reviews
Search Southwest flights

Traveling to a place near Minneapolis?

Book flights to Minneapolis if you plan to visit one of these locations
Bloomington
Saint Paul
Brooklyn Center
Eagan
Shakopee
Maple Grove
Coon Rapids
Burnsville
Plymouth
Roseville
Red Wing
Brooklyn Park
Prior Lake
Stillwater
Richfield
Hudson
Eden Prairie
Owatonna
Woodbury
Hinckley

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Minneapolis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Minneapolis for you.

Can I find flights from Myrtle Beach to Minneapolis with flexible booking policies on momondo?

Yes. All flights to Minneapolis from Myrtle Beach on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Myrtle Beach to Minneapolis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Minneapolis from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to Minneapolis right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Minneapolis, momondo offers a useful price alert feature which will track prices for flights to Minneapolis from Myrtle Beach and alert you when they change.

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