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Cheap flights from Myrtle Beach to Louisville from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Louisville departing on 10/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to Louisville

Cheap round-trip flights

Spirit Airlines Logo
4:23 pm - 10:04 pmMYR-SDF
5h 41m1 stop
Spirit Airlines Logo
8:23 am - 8:06 pmSDF-MYR
11h 43m1 stop
$166Spirit Airlines
Find Deal
Sat, Sep 27 - Sat, Oct 4
Spirit Airlines Logo
4:15 pm - 9:19 amMYR-SDF
17h 04m1 stop
Spirit Airlines Logo
8:23 am - 8:06 pmSDF-MYR
11h 43m1 stop
$202Spirit Airlines
Find Deal
Wed, Sep 17 - Mon, Sep 22
Spirit Airlines Logo
6:00 am - 10:04 pmMYR-SDF
16h 04m2 stops
Spirit Airlines Logo
8:23 am - 8:06 pmSDF-MYR
11h 43m1 stop
$203Spirit Airlines
Find Deal
Fri, Sep 5 - Tue, Sep 9
Spirit Airlines Logo
5:20 pm - 9:19 amMYR-SDF
15h 59m1 stop
Spirit Airlines Logo
8:23 am - 8:06 pmSDF-MYR
11h 43m1 stop
$207Spirit Airlines
Find Deal
Thu, Sep 11 - Tue, Sep 16
Spirit Airlines Logo
7:17 pm - 9:19 amMYR-SDF
14h 02m1 stop
Spirit Airlines Logo
8:23 am - 8:06 pmSDF-MYR
11h 43m1 stop
$217Spirit Airlines
Find Deal
Fri, Sep 12 - Fri, Sep 19
Delta Logo
6:55 pm - 11:52 pmMYR-SDF
4h 57m1 stop
Delta Logo
6:00 am - 10:10 amSDF-MYR
4h 10m1 stop
$241Delta
Find Deal
Thu, Sep 11 - Wed, Sep 17
Delta Logo
6:55 pm - 11:52 pmMYR-SDF
4h 57m1 stop
Delta Logo
5:56 pm - 11:49 pmSDF-MYR
5h 53m1 stop
$245Delta
Find Deal
Thu, Sep 11 - Sat, Sep 13
Delta Logo
6:55 pm - 10:51 pmMYR-SDF
3h 56m1 stop
Delta Logo
6:00 am - 11:36 amSDF-MYR
5h 36m1 stop
$251Delta
Find Deal
Fri, Sep 12 - Wed, Sep 17
Delta Logo
6:55 pm - 11:52 pmMYR-SDF
4h 57m1 stop
Delta Logo
6:00 am - 11:36 amSDF-MYR
5h 36m1 stop
$255Delta
Find Deal
Thu, Sep 11 - Fri, Sep 19
Logo
4:15 pm - 10:04 pmMYR-SDF
29h 49m2 stops
Logo
11:17 am - 8:06 pmSDF-MYR
8h 49m1 stop
$273
Find Deal
Wed, Sep 17 - Mon, Sep 22

Spirit Airlines flights from Myrtle Beach to Louisville

Our best Spirit Airlines deals on Myrtle Beach to Louisville flight tickets
Spirit Airlines
Sep 27
MYR4:23 pmMyrtle Beach Intl
5h 41m
1 stop
SDF10:04 pmLouisville Intl
Oct 4
SDF8:23 amLouisville Intl
11h 43m
1 stop
MYR8:06 pmMyrtle Beach Intl
$166
Find similar
Spirit Airlines
Sep 17
MYR4:15 pmMyrtle Beach Intl
17h 04m
1 stop
SDF9:19 amLouisville Intl
Sep 22
SDF8:23 amLouisville Intl
11h 43m
1 stop
MYR8:06 pmMyrtle Beach Intl
$202
Find similar
Spirit Airlines
Sep 5
MYR6:00 amMyrtle Beach Intl
16h 04m
2 stops
SDF10:04 pmLouisville Intl
Sep 9
SDF8:23 amLouisville Intl
11h 43m
1 stop
MYR8:06 pmMyrtle Beach Intl
$203
Find similar

Delta flights from Myrtle Beach to Louisville

Our best Delta deals on Myrtle Beach to Louisville flight tickets
Delta
Sep 11
MYR6:55 pmMyrtle Beach Intl
4h 57m
1 stop
SDF11:52 pmLouisville Intl
Sep 17
SDF6:00 amLouisville Intl
4h 10m
1 stop
MYR10:10 amMyrtle Beach Intl
$241
Find similar
Delta
Sep 11
MYR6:55 pmMyrtle Beach Intl
4h 57m
1 stop
SDF11:52 pmLouisville Intl
Sep 13
SDF5:56 pmLouisville Intl
5h 53m
1 stop
MYR11:49 pmMyrtle Beach Intl
$245
Find similar
Delta
Sep 12
MYR6:55 pmMyrtle Beach Intl
3h 56m
1 stop
SDF10:51 pmLouisville Intl
Sep 17
SDF6:00 amLouisville Intl
5h 36m
1 stop
MYR11:36 amMyrtle Beach Intl
$251
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Sat 9/27

4:23 pm-10:04 pm

1 stop5h 41m

Louisville Intl

Sat 10/4

8:23 am-8:06 pm

1 stop11h 43m

$166

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Wed 9/17

4:15 pm-9:19 am

1 stop17h 04m

Louisville Intl

Mon 9/22

8:23 am-8:06 pm

1 stop11h 43m

$202

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Fri 9/5

6:00 am-10:04 pm

2 stops16h 04m

Louisville Intl

Tue 9/9

8:23 am-8:06 pm

1 stop11h 43m

$203

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 9/11

5:20 pm-9:19 am

1 stop15h 59m

Louisville Intl

Tue 9/16

8:23 am-8:06 pm

1 stop11h 43m

$207

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Fri 9/12

7:17 pm-9:19 am

1 stop14h 02m

Louisville Intl

Fri 9/19

8:23 am-8:06 pm

1 stop11h 43m

$217

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 9/11

6:55 pm-11:52 pm

1 stop4h 57m

Louisville Intl

Wed 9/17

6:00 am-10:10 am

1 stop4h 10m

$241

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 9/11

6:55 pm-11:52 pm

1 stop4h 57m

Louisville Intl

Sat 9/13

5:56 pm-11:49 pm

1 stop5h 53m

$245

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Fri 9/12

6:55 pm-10:51 pm

1 stop3h 56m

Louisville Intl

Wed 9/17

6:00 am-11:36 am

1 stop5h 36m

$251

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 9/11

6:55 pm-11:52 pm

1 stop4h 57m

Louisville Intl

Fri 9/19

6:00 am-11:36 am

1 stop5h 36m

$255

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Wed 9/17

4:15 pm-10:04 pm

2 stops29h 49m

Louisville Intl

Mon 9/22

11:17 am-8:06 pm

1 stop8h 49m

$273

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from Myrtle Beach to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from Myrtle Beach is on a Saturday. momondo users have found tickets for Saturday departures for as low as $143. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Myrtle Beach to Louisville on a Sunday will generally be more expensive and average around $390. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Louisville?

Our data shows that the cheapest Myrtle Beach to Louisville flights are usually those with departure times in the afternoon. Our users have found flights to Louisville in the afternoon for as low as $133. In the evening is when there is more demand to fly to Louisville, so prices are often more expensive at around $308 per ticket.

What is the cheapest Myrtle Beach Intl to Louisville Intl flight route?

Fly from Myrtle Beach Intl to Louisville Intl for the best Myrtle Beach Intl - Louisville Intl flight prices

What cabin class options are available on Myrtle Beach Intl to Louisville Intl flights?

There are 1 cabin classes available to choose from on Myrtle Beach Intl to Louisville Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Louisville flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Louisville.

When to book flights from Myrtle Beach to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Louisville (MYR to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Louisville

Direct flights

None
There are no direct flights from Myrtle Beach to Louisville. There are no popular flight routes from Myrtle Beach to Louisville.
Search flight deals

  • How far is Myrtle Beach Intl to Louisville Intl by plane?

    The straight-line distance from Myrtle Beach Intl to Louisville Intl is 496.1 mi. Flights usually cover this in 3h 56m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Louisville Intl Airport?

    Prices for flights from Myrtle Beach Intl Airport to Louisville Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Louisville Intl Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Louisville Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Myrtle Beach to Louisville?

  • What is the most popular airline from Myrtle Beach to Louisville?

Best airlines flying from Myrtle Beach to Louisville

Compare and see reviews for airlines that fly from Myrtle Beach to Louisville with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $31Free CancellationRating
6.3
8,035 reviews
Search Spirit Airlines flights
DeltaPriceFrom $196Free CancellationRating
7.9
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $242Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Corydon
Elizabeth
Charlestown
Springfield
Brandenburg
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Louisville?

Finding the right flight to Louisville from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Louisville quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Louisville with flexible booking policies on momondo?

Yes. All flights to Louisville from Myrtle Beach on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Myrtle Beach to Louisville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Louisville.

I’m not ready to book a flight from Myrtle Beach to Louisville right now. Can momondo alert me if prices change?

Price alerts on flights to Louisville from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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