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Cheap flights from Myrtle Beach to Louisville from $70

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Louisville departing on 7/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:41 pm - 12:28 am
MYR
-
SDF
3h 47m
1 stop
American Airlines Logo
6:01 am - 11:37 am
SDF
-
MYR
5h 36m
1 stop
$303American Airlines
Thu, Jun 11 - Wed, Jun 17
Delta Logo
6:00 am - 9:53 am
MYR
-
SDF
3h 53m
1 stop
Delta Logo
7:30 pm - 11:39 pm
SDF
-
MYR
4h 09m
1 stop
$309Delta
Wed, Sep 23 - Mon, Sep 28
American Airlines Logo
6:33 am - 12:41 pm
MYR
-
SDF
6h 08m
1 stop
American Airlines Logo
5:43 pm - 9:47 pm
SDF
-
MYR
4h 04m
1 stop
$323American Airlines
Fri, May 29 - Fri, May 29
American Airlines Logo
6:06 pm - 12:28 am
MYR
-
SDF
6h 22m
1 stop
American Airlines Logo
8:08 pm - 11:49 pm
SDF
-
MYR
3h 41m
1 stop
$329American Airlines
Fri, Jun 26 - Sat, Jun 27
United Airlines Logo
10:34 am - 8:23 pm
MYR
-
SDF
9h 49m
2 stops
United Airlines Logo
6:00 am - 9:59 am
SDF
-
MYR
3h 59m
1 stop
$339United Airlines
Wed, Jun 10 - Sun, Jun 14
Southwest Logo
7:50 am - 12:30 pm
MYR
-
SDF
4h 40m
1 stop
Southwest Logo
6:05 pm - 9:20 pm
SDF
-
MYR
3h 15m
1 stop
$345Southwest
Thu, Jun 11 - Thu, Jun 18
Southwest Logo
8:10 pm - 12:25 am
MYR
-
SDF
4h 15m
1 stop
Southwest Logo
5:05 pm - 9:40 pm
SDF
-
MYR
4h 35m
1 stop
$347Southwest
Mon, Jun 15 - Mon, Jun 22
Southwest Logo
8:10 pm - 12:25 am
MYR
-
SDF
4h 15m
1 stop
Southwest Logo
8:45 am - 8:30 pm
SDF
-
MYR
11h 45m
2 stops
$349Southwest
Thu, Jun 11 - Wed, Jun 17
Southwest Logo
2:00 pm - 10:25 pm
MYR
-
SDF
8h 25m
2 stops
Southwest Logo
3:35 pm - 10:45 pm
SDF
-
MYR
7h 10m
1 stop
$352Southwest
Mon, Jun 15 - Mon, Jun 22
Delta Logo
2:15 pm - 8:52 pm
MYR
-
SDF
6h 37m
1 stop
Delta Logo
7:30 pm - 11:39 pm
SDF
-
MYR
4h 09m
1 stop
$353Delta
Thu, Sep 24 - Mon, Sep 28

Southwest flights from Myrtle Beach to Louisville

Our best Southwest deals on Myrtle Beach to Louisville flight tickets
Southwest
Jun 11
MYR7:50 amMyrtle Beach Intl
4h 40m
1 stop
SDF12:30 pmLouisville Intl
Jun 18
SDF6:05 pmLouisville Intl
3h 15m
1 stop
MYR9:20 pmMyrtle Beach Intl
$345
Southwest
Jun 15
MYR8:10 pmMyrtle Beach Intl
4h 15m
1 stop
SDF12:25 amLouisville Intl
Jun 22
SDF5:05 pmLouisville Intl
4h 35m
1 stop
MYR9:40 pmMyrtle Beach Intl
$347
Southwest
Jun 11
MYR8:10 pmMyrtle Beach Intl
4h 15m
1 stop
SDF12:25 amLouisville Intl
Jun 17
SDF8:45 amLouisville Intl
11h 45m
2 stops
MYR8:30 pmMyrtle Beach Intl
$349

Delta flights from Myrtle Beach to Louisville

Our best Delta deals on Myrtle Beach to Louisville flight tickets
Delta
Sep 23
MYR6:00 amMyrtle Beach Intl
3h 53m
1 stop
SDF9:53 amLouisville Intl
Sep 28
SDF7:30 pmLouisville Intl
4h 09m
1 stop
MYR11:39 pmMyrtle Beach Intl
$309
Delta
Sep 24
MYR2:15 pmMyrtle Beach Intl
6h 37m
1 stop
SDF8:52 pmLouisville Intl
Sep 28
SDF7:30 pmLouisville Intl
4h 09m
1 stop
MYR11:39 pmMyrtle Beach Intl
$353
Delta
Jun 5
MYR4:07 pmMyrtle Beach Intl
5h 12m
1 stop
SDF9:19 pmLouisville Intl
Jun 8
SDF6:34 pmLouisville Intl
5h 25m
1 stop
MYR11:59 pmMyrtle Beach Intl
$387

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 16, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 6/11

8:41 pm-12:28 am

1 stop3h 47m

Louisville Intl

Wed 6/17

6:01 am-11:37 am

1 stop5h 36m

$303

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Wed 9/23

6:00 am-9:53 am

1 stop3h 53m

Louisville Intl

Mon 9/28

7:30 pm-11:39 pm

1 stop4h 09m

$309

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Fri 5/29

6:33 am-12:41 pm

1 stop6h 08m

Louisville Intl

Fri 5/29

5:43 pm-9:47 pm

1 stop4h 04m

$323

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Fri 6/26

6:06 pm-12:28 am

1 stop6h 22m

Louisville Intl

Sat 6/27

8:08 pm-11:49 pm

1 stop3h 41m

$329

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Wed 6/10

10:34 am-8:23 pm

2 stops9h 49m

Louisville Intl

Sun 6/14

6:00 am-9:59 am

1 stop3h 59m

$339
Quickest round-trip

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 6/11

7:50 am-12:30 pm

1 stop4h 40m

Louisville Intl

Thu 6/18

6:05 pm-9:20 pm

1 stop3h 15m

$345

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Mon 6/15

8:10 pm-12:25 am

1 stop4h 15m

Louisville Intl

Mon 6/22

5:05 pm-9:40 pm

1 stop4h 35m

$347

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 6/11

8:10 pm-12:25 am

1 stop4h 15m

Louisville Intl

Wed 6/17

8:45 am-8:30 pm

2 stops11h 45m

$349

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Mon 6/15

2:00 pm-10:25 pm

2 stops8h 25m

Louisville Intl

Mon 6/22

3:35 pm-10:45 pm

1 stop7h 10m

$352

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 9/24

2:15 pm-8:52 pm

1 stop6h 37m

Louisville Intl

Mon 9/28

7:30 pm-11:39 pm

1 stop4h 09m

$353

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from Myrtle Beach to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Louisville?

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of March, then departing from Myrtle Beach during the month May is also very affordable. Most momondo users find prices during this month for around $31.

What is the cheapest Myrtle Beach Intl to Louisville Intl flight route?

Fly from Myrtle Beach Intl to Louisville Intl for the best Myrtle Beach Intl - Louisville Intl flight prices

Can stopping save me money on Myrtle Beach to Louisville flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Louisville.

How have Myrtle Beach to Louisville flight prices changed over time?

As of May 2026, prices for Myrtle Beach to Louisville flights are approximately 33% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Louisville (MYR to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Louisville

Fastest flight time

3h 58m

Direct flights

Sun

Airports in Louisville

1 airport
The fastest flight from Myrtle Beach to Louisville takes 3h 58m
Direct flights go from Myrtle Beach to Louisville on Sunday. There are no airlines offering direct flights.
There is 1 airport in Louisville. From Myrtle Beach there are direct flights to Louisville Intl (SDF).
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Louisville

  • How far is Myrtle Beach Intl to Louisville Intl by plane?

    The straight-line distance from Myrtle Beach Intl to Louisville Intl is 496.1 mi. Flights usually cover this in 3h 58m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Louisville Intl Airport?

    Prices for flights from Myrtle Beach Intl Airport to Louisville Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Louisville Intl Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Louisville Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Myrtle Beach to Louisville?

  • What is the most popular airline from Myrtle Beach to Louisville?

Best airlines flying from Myrtle Beach to Louisville

Compare and see reviews for airlines that fly from Myrtle Beach to Louisville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,455 reviews
Search Delta flights
American AirlinesPriceFrom $256Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
Jeffersonville
West Baden Springs
Bardstown
New Albany
Shepherdsville
Brandenburg
Corydon
Elizabeth
Charlestown
Georgetown
Springfield

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Louisville?

Finding the right flight to Louisville from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Louisville quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Louisville with flexible booking policies on momondo?

Yes. All flights to Louisville from Myrtle Beach on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Myrtle Beach to Louisville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Louisville.

I’m not ready to book a flight from Myrtle Beach to Louisville right now. Can momondo alert me if prices change?

Price alerts on flights to Louisville from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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