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Cheap flights from Myrtle Beach to Santo Domingo from $269

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Santo Domingo departing on 9/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 1:00 pm
MYR
-
SDQ
7h 00m
1 stop
American Airlines Logo
2:00 pm - 11:17 pm
SDQ
-
MYR
9h 17m
1 stop
$550American Airlines
Fri, Aug 14 - Fri, Aug 21
American Airlines Logo
6:00 am - 6:44 pm
MYR
-
SDQ
12h 44m
2 stops
American Airlines Logo
7:00 am - 10:08 pm
SDQ
-
MYR
15h 08m
2 stops
$555American Airlines
Fri, Aug 14 - Fri, Aug 21
Multiple Airlines Logo
4:21 pm - 11:45 am
MYR
-
SDQ
19h 24m
1 stop
Multiple Airlines Logo
3:30 pm - 9:50 am
SDQ
-
MYR
42h 20m
2 stops
$562Multiple Airlines
Sat, Aug 15 - Sat, Aug 22
American Airlines Logo
7:30 am - 6:34 pm
MYR
-
SDQ
11h 04m
2 stops
American Airlines Logo
7:34 pm - 2:37 pm
SDQ
-
MYR
19h 03m
2 stops
$580American Airlines
Fri, Sep 18 - Sun, Sep 20
American Airlines Logo
7:16 pm - 12:35 pm
MYR
-
SDQ
17h 19m
1 stop
American Airlines Logo
3:00 pm - 10:04 am
SDQ
-
MYR
20h 04m
1 stop
$582American Airlines
Fri, Oct 30 - Tue, Nov 10
American Airlines Logo
3:10 pm - 12:35 pm
MYR
-
SDQ
21h 25m
1 stop
American Airlines Logo
1:12 pm - 10:05 pm
SDQ
-
MYR
9h 53m
2 stops
$586American Airlines
Fri, Oct 30 - Tue, Nov 10
American Airlines Logo
6:00 am - 1:00 pm
MYR
-
SDQ
7h 00m
1 stop
American Airlines Logo
2:00 pm - 11:17 pm
SDQ
-
MYR
9h 17m
1 stop
$590American Airlines
Sat, Aug 15 - Sat, Aug 22
American Airlines Logo
5:03 am - 5:23 pm
MYR
-
SDQ
11h 20m
2 stops
American Airlines Logo
1:12 pm - 11:55 pm
SDQ
-
MYR
11h 43m
2 stops
$595American Airlines
Sat, Nov 14 - Sat, Nov 21
American Airlines Logo
6:00 am - 6:44 pm
MYR
-
SDQ
12h 44m
2 stops
American Airlines Logo
7:00 am - 11:50 pm
SDQ
-
MYR
16h 50m
2 stops
$600American Airlines
Sun, Aug 16 - Sun, Aug 23
American Airlines Logo
6:40 pm - 2:00 pm
MYR
-
SDQ
18h 20m
1 stop
American Airlines Logo
1:12 pm - 11:55 pm
SDQ
-
MYR
11h 43m
2 stops
$603American Airlines
Sat, Nov 14 - Sat, Nov 21

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American Airlines flights from Myrtle Beach to Santo Domingo

Our best American Airlines deals on Myrtle Beach to Santo Domingo flight tickets
American Airlines
Aug 14
MYR6:00 amMyrtle Beach Intl
7h 00m
1 stop
SDQ1:00 pmSanto Domingo Las Americas
Aug 21
SDQ2:00 pmSanto Domingo Las Americas
9h 17m
1 stop
MYR11:17 pmMyrtle Beach Intl
$550
American Airlines
Aug 14
MYR6:00 amMyrtle Beach Intl
7h 00m
1 stop
SDQ1:00 pmSanto Domingo Las Americas
Aug 21
SDQ7:00 amSanto Domingo Las Americas
15h 42m
2 stops
MYR10:42 pmMyrtle Beach Intl
$555
American Airlines
Sep 18
MYR7:30 amMyrtle Beach Intl
11h 04m
2 stops
SDQ6:34 pmSanto Domingo Las Americas
Sep 20
SDQ7:34 pmSanto Domingo Las Americas
19h 03m
2 stops
MYR2:37 pmMyrtle Beach Intl
$580

Delta flights from Myrtle Beach to Santo Domingo

Our best Delta deals on Myrtle Beach to Santo Domingo flight tickets
Delta
Sep 8
MYR6:00 amMyrtle Beach Intl
7h 27m
1 stop
SDQ1:27 pmSanto Domingo Las Americas
Sep 11
SDQ2:53 pmSanto Domingo Las Americas
6h 49m
1 stop
MYR9:42 pmMyrtle Beach Intl
$695
Delta
Jul 8
MYR4:34 pmMyrtle Beach Intl
20h 05m
2 stops
SDQ12:39 pmSanto Domingo Las Americas
Jul 12
SDQ7:35 pmSanto Domingo Las Americas
20h 04m
2 stops
MYR3:39 pmMyrtle Beach Intl
$830
Delta
Sep 18
MYR6:00 amMyrtle Beach Intl
12h 07m
2 stops
SDQ6:07 pmSanto Domingo Las Americas
Sep 20
SDQ2:53 pmSanto Domingo Las Americas
8h 36m
1 stop
MYR11:29 pmMyrtle Beach Intl
$915

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Fri 8/14

6:00 am-1:00 pm

1 stop7h 00m

Santo Domingo Las Americas

Fri 8/21

2:00 pm-11:17 pm

1 stop9h 17m

$550

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Fri 8/14

6:00 am-6:44 pm

2 stops12h 44m

Santo Domingo Las Americas

Fri 8/21

7:00 am-10:08 pm

2 stops15h 08m

$555

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sat 8/15

4:21 pm-11:45 am

1 stop19h 24m

Santo Domingo Las Americas

Sat 8/22

3:30 pm-9:50 am

2 stops42h 20m

$562

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Fri 9/18

7:30 am-6:34 pm

2 stops11h 04m

Santo Domingo Las Americas

Sun 9/20

7:34 pm-2:37 pm

2 stops19h 03m

$580

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Fri 10/30

7:16 pm-12:35 pm

1 stop17h 19m

Santo Domingo Las Americas

Tue 11/10

3:00 pm-10:04 am

1 stop20h 04m

$582

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Fri 10/30

3:10 pm-12:35 pm

1 stop21h 25m

Santo Domingo Las Americas

Tue 11/10

1:12 pm-10:05 pm

2 stops9h 53m

$586

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sat 8/15

6:00 am-1:00 pm

1 stop7h 00m

Santo Domingo Las Americas

Sat 8/22

2:00 pm-11:17 pm

1 stop9h 17m

$590

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sat 11/14

5:03 am-5:23 pm

2 stops11h 20m

Santo Domingo Las Americas

Sat 11/21

1:12 pm-11:55 pm

2 stops11h 43m

$595

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sun 8/16

6:00 am-6:44 pm

2 stops12h 44m

Santo Domingo Las Americas

Sun 8/23

7:00 am-11:50 pm

2 stops16h 50m

$600

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sat 11/14

6:40 pm-2:00 pm

1 stop18h 20m

Santo Domingo Las Americas

Sat 11/21

1:12 pm-11:55 pm

2 stops11h 43m

$603

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Myrtle Beach to Santo Domingo flights?

You could potentially save up to 69% on your flight if you consider stops on a Myrtle Beach to Santo Domingo flight.

When to book flights from Myrtle Beach to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Santo Domingo (MYR to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Santo Domingo

Fastest flight time

7h 17m

Direct flights

None
The fastest flight from Myrtle Beach to Santo Domingo takes 7h 17m
There are no direct flights from Myrtle Beach to Santo Domingo. There are no popular flight routes from Myrtle Beach to Santo Domingo.
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Frequently asked questions about flying from Myrtle Beach to Santo Domingo

  • How far is Myrtle Beach Intl to Santo Domingo Las Americas by plane?

    A flight from Myrtle Beach Intl to Santo Domingo Las Americas will travel around 1186.3 mi. 7h 17m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Santo Domingo?

Best airlines flying from Myrtle Beach to Santo Domingo

Compare and see reviews for airlines that fly from Myrtle Beach to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $297Free CancellationRating
7.8
8,454 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Myrtle Beach.

Can I find flights from Myrtle Beach to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Santo Domingo?

Once you have performed a search for Myrtle Beach to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Myrtle Beach to Santo Domingo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Santo Domingo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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