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Cheap flights from Myrtle Beach to Santo Domingo from $239

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Santo Domingo departing on 12/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:00 am - 4:26 pm
MYR
-
SDQ
29h 26m1 stop
Multiple Airlines Logo
3:32 pm - 7:20 pm
SDQ
-
MYR
28h 48m1 stop
$356Multiple Airlines
mar., ene. 27 - dom., feb. 1
Spirit Airlines Logo
10:00 am - 2:27 pm
MYR
-
SDQ
27h 27m2 stops
Spirit Airlines Logo
3:32 pm - 7:20 pm
SDQ
-
MYR
28h 48m1 stop
$376Spirit Airlines
mar., ene. 27 - dom., feb. 1
American Airlines Logo
5:29 pm - 3:45 pm
MYR
-
SDQ
21h 16m2 stops
American Airlines Logo
4:47 pm - 9:48 am
SDQ
-
MYR
18h 01m2 stops
$487American Airlines
mar., ene. 27 - dom., feb. 1
American Airlines Logo
8:00 am - 5:23 pm
MYR
-
SDQ
8h 23m2 stops
American Airlines Logo
4:47 pm - 9:48 am
SDQ
-
MYR
18h 01m2 stops
$512American Airlines
mié., ene. 21 - dom., ene. 25
Delta Logo
6:00 am - 2:21 pm
MYR
-
SDQ
7h 21m1 stop
Delta Logo
3:46 pm - 11:41 pm
SDQ
-
MYR
8h 55m1 stop
$748Delta
mié., ene. 21 - dom., ene. 25
Delta Logo
6:00 am - 2:21 pm
MYR
-
SDQ
7h 21m1 stop
Delta Logo
7:31 am - 5:59 pm
SDQ
-
MYR
11h 28m2 stops
$752Delta
mié., ene. 21 - dom., ene. 25

American Airlines flights from Myrtle Beach to Santo Domingo

Our best American Airlines deals on Myrtle Beach to Santo Domingo flight tickets
American Airlines
Jan 27
MYR7:19 pmMyrtle Beach Intl
21h 04m
2 stops
SDQ5:23 pmSanto Domingo Las Americas
Feb 1
SDQ6:29 pmSanto Domingo Las Americas
18h 15m
2 stops
MYR11:44 amMyrtle Beach Intl
$487
Find similar
American Airlines
Jan 21
MYR8:00 amMyrtle Beach Intl
8h 23m
2 stops
SDQ5:23 pmSanto Domingo Las Americas
Jan 25
SDQ4:47 pmSanto Domingo Las Americas
18h 01m
2 stops
MYR9:48 amMyrtle Beach Intl
$512
Find similar

Delta flights from Myrtle Beach to Santo Domingo

Our best Delta deals on Myrtle Beach to Santo Domingo flight tickets
Delta
Jan 27
MYR4:00 pmMyrtle Beach Intl
20h 10m
2 stops
SDQ1:10 pmSanto Domingo Las Americas
Feb 1
SDQ3:46 pmSanto Domingo Las Americas
8h 55m
1 stop
MYR11:41 pmMyrtle Beach Intl
$673
Find similar
Delta
Jan 21
MYR6:00 amMyrtle Beach Intl
7h 21m
1 stop
SDQ2:21 pmSanto Domingo Las Americas
Jan 25
SDQ3:46 pmSanto Domingo Las Americas
8h 55m
1 stop
MYR11:41 pmMyrtle Beach Intl
$748
Find similar
Delta
Jan 21
MYR6:00 amMyrtle Beach Intl
7h 21m
1 stop
SDQ2:21 pmSanto Domingo Las Americas
Jan 25
SDQ7:31 amSanto Domingo Las Americas
11h 28m
2 stops
MYR5:59 pmMyrtle Beach Intl
$752
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mar. 1/27

10:00 am-4:26 pm

1 stop29h 26m

Santo Domingo Las Americas

dom. 2/1

3:32 pm-7:20 pm

1 stop28h 48m

$356

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mar. 1/27

10:00 am-2:27 pm

2 stops27h 27m

Santo Domingo Las Americas

dom. 2/1

3:32 pm-7:20 pm

1 stop28h 48m

$376

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mar. 1/27

5:29 pm-3:45 pm

2 stops21h 16m

Santo Domingo Las Americas

dom. 2/1

4:47 pm-9:48 am

2 stops18h 01m

$487

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mié. 1/21

8:00 am-5:23 pm

2 stops8h 23m

Santo Domingo Las Americas

dom. 1/25

4:47 pm-9:48 am

2 stops18h 01m

$512

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mié. 1/21

6:00 am-2:21 pm

1 stop7h 21m

Santo Domingo Las Americas

dom. 1/25

3:46 pm-11:41 pm

1 stop8h 55m

$748

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mié. 1/21

6:00 am-2:21 pm

1 stop7h 21m

Santo Domingo Las Americas

dom. 1/25

7:31 am-5:59 pm

2 stops11h 28m

$752

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mié. 12/24

9:54 am-2:54 am

1 stop16h 00m

$239

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mié. 12/24

9:54 am-2:54 am

1 stop16h 00m

$264

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mié. 12/24

9:54 am-2:54 am

1 stop16h 00m

$270

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

mié. 12/24

2:34 pm-3:51 pm

2 stops24h 17m

$471

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Myrtle Beach to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $390. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $880.

Can stopping save me money on Myrtle Beach to Santo Domingo flights?

You could potentially save up to 26% on your flight if you consider stops on a Myrtle Beach to Santo Domingo flight.

When to book flights from Myrtle Beach to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Santo Domingo (MYR to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Santo Domingo

Fastest flight time

16h 07m

Direct flights

None
The fastest flight from Myrtle Beach to Santo Domingo takes 16h 07m
There are no direct flights from Myrtle Beach to Santo Domingo. There are no popular flight routes from Myrtle Beach to Santo Domingo.
Search flight deals

  • How far is Myrtle Beach Intl to Santo Domingo Las Americas by plane?

    A flight from Myrtle Beach Intl to Santo Domingo Las Americas will travel around 1186.3 mi. 16h 07m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Santo Domingo?

Best airlines flying from Myrtle Beach to Santo Domingo

Compare and see reviews for airlines that fly from Myrtle Beach to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $514Free CancellationRating
7.9
8,010 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Myrtle Beach.

Can I find flights from Myrtle Beach to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Santo Domingo?

Once you have performed a search for Myrtle Beach to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Myrtle Beach to Santo Domingo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Santo Domingo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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