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Cheap flights from Myrtle Beach to Key West from $129

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 4/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
5:53 pm - 9:09 am
MYR
-
EYW
15h 16m
1 stop
Breeze Airways Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$254Breeze Airways
Sun, Mar 29 - Thu, Apr 2
Breeze Airways Logo
6:18 pm - 12:21 pm
MYR
-
EYW
18h 03m
1 stop
Breeze Airways Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$260Breeze Airways
Mon, Mar 30 - Thu, Apr 2
Breeze Airways Logo
6:59 pm - 9:09 am
MYR
-
EYW
14h 10m
1 stop
Breeze Airways Logo
11:04 am - 11:39 am
EYW
-
MYR
24h 35m
1 stop
$265Breeze Airways
Sun, May 3 - Thu, May 7
Multiple Airlines Logo
5:53 pm - 9:09 am
MYR
-
EYW
15h 16m
1 stop
Multiple Airlines Logo
11:51 am - 11:05 am
EYW
-
MYR
23h 14m
1 stop
$271Multiple Airlines
Sun, Mar 29 - Wed, Apr 1
Multiple Airlines Logo
6:28 pm - 9:06 am
MYR
-
EYW
14h 38m
2 stops
Multiple Airlines Logo
11:51 am - 2:22 pm
EYW
-
MYR
26h 31m
1 stop
$273Multiple Airlines
Sat, Mar 28 - Wed, Apr 1
Multiple Airlines Logo
5:53 pm - 2:43 pm
MYR
-
EYW
20h 50m
1 stop
Multiple Airlines Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$281Multiple Airlines
Thu, Apr 16 - Thu, Apr 23
Multiple Airlines Logo
4:40 pm - 11:30 am
MYR
-
EYW
18h 50m
1 stop
Multiple Airlines Logo
11:51 am - 2:22 pm
EYW
-
MYR
26h 31m
1 stop
$282Multiple Airlines
Sat, Mar 28 - Wed, Apr 1
Multiple Airlines Logo
6:18 pm - 12:21 pm
MYR
-
EYW
18h 03m
1 stop
Multiple Airlines Logo
2:30 pm - 11:29 pm
EYW
-
MYR
8h 59m
1 stop
$283Multiple Airlines
Mon, Apr 20 - Mon, Apr 27
Multiple Airlines Logo
6:59 pm - 9:09 am
MYR
-
EYW
14h 10m
1 stop
Multiple Airlines Logo
3:19 pm - 8:30 am
EYW
-
MYR
41h 11m
2 stops
$286Multiple Airlines
Sun, May 3 - Thu, May 7
Multiple Airlines Logo
6:18 pm - 11:04 am
MYR
-
EYW
16h 46m
1 stop
Multiple Airlines Logo
2:30 pm - 11:29 pm
EYW
-
MYR
8h 59m
1 stop
$288Multiple Airlines
Fri, Apr 10 - Fri, Apr 17

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Mar 29
MYR5:53 pmMyrtle Beach Intl
15h 16m
1 stop
EYW9:09 amKey West
Apr 2
EYW9:46 amKey West
4h 36m
1 stop
MYR2:22 pmMyrtle Beach Intl
$254
Breeze Airways
Mar 30
MYR6:18 pmMyrtle Beach Intl
18h 03m
1 stop
EYW12:21 pmKey West
Apr 2
EYW9:46 amKey West
4h 36m
1 stop
MYR2:22 pmMyrtle Beach Intl
$260
Breeze Airways
May 3
MYR6:59 pmMyrtle Beach Intl
14h 10m
1 stop
EYW9:09 amKey West
May 7
EYW11:04 amKey West
24h 35m
1 stop
MYR11:39 amMyrtle Beach Intl
$265

Spirit Airlines flights from Myrtle Beach to Key West

Our best Spirit Airlines deals on Myrtle Beach to Key West flight tickets
Spirit Airlines
Mar 29
MYR12:05 pmMyrtle Beach Intl
25h 32m
3 stops
EYW1:37 pmKey West
Apr 2
EYW12:25 pmKey West
5h 08m
1 stop
MYR5:33 pmMyrtle Beach Intl
$464
Spirit Airlines
Mar 29
MYR12:05 pmMyrtle Beach Intl
25h 32m
3 stops
EYW1:37 pmKey West
Apr 1
EYW12:25 pmKey West
5h 08m
1 stop
MYR5:33 pmMyrtle Beach Intl
$512
Spirit Airlines
Mar 30
MYR10:01 amMyrtle Beach Intl
25h 29m
3 stops
EYW11:30 amKey West
Apr 2
EYW12:25 pmKey West
5h 08m
1 stop
MYR5:33 pmMyrtle Beach Intl
$518

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 3/29

5:53 pm-9:09 am

1 stop15h 16m

Key West

Thu 4/2

9:46 am-2:22 pm

1 stop4h 36m

$254

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 3/30

6:18 pm-12:21 pm

1 stop18h 03m

Key West

Thu 4/2

9:46 am-2:22 pm

1 stop4h 36m

$260

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 5/3

6:59 pm-9:09 am

1 stop14h 10m

Key West

Thu 5/7

11:04 am-11:39 am

1 stop24h 35m

$265

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 3/29

5:53 pm-9:09 am

1 stop15h 16m

Key West

Wed 4/1

11:51 am-11:05 am

1 stop23h 14m

$271

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 3/28

6:28 pm-9:06 am

2 stops14h 38m

Key West

Wed 4/1

11:51 am-2:22 pm

1 stop26h 31m

$273

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 4/16

5:53 pm-2:43 pm

1 stop20h 50m

Key West

Thu 4/23

9:46 am-2:22 pm

1 stop4h 36m

$281

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 3/28

4:40 pm-11:30 am

1 stop18h 50m

Key West

Wed 4/1

11:51 am-2:22 pm

1 stop26h 31m

$282

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 4/20

6:18 pm-12:21 pm

1 stop18h 03m

Key West

Mon 4/27

2:30 pm-11:29 pm

1 stop8h 59m

$283

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 5/3

6:59 pm-9:09 am

1 stop14h 10m

Key West

Thu 5/7

3:19 pm-8:30 am

2 stops41h 11m

$286

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 4/10

6:18 pm-11:04 am

1 stop16h 46m

Key West

Fri 4/17

2:30 pm-11:29 pm

1 stop8h 59m

$288

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $308. If you are unable to visit Key West during the month of August, then departing from Myrtle Beach during the month June is also very affordable. Most momondo users find prices during this month for around $338.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 16% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

4h 46m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 4h 46m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 46m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,286 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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