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Cheap flights from Myrtle Beach to Key West from $116

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 3/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
9:09 am - 1:30 pm
MYR
-
EYW
4h 21m
1 stop
Spirit Airlines Logo
2:25 pm - 8:13 am
EYW
-
MYR
17h 48m
1 stop
$268Spirit Airlines
Mon, Feb 16 - Fri, Feb 20
Multiple Airlines Logo
9:09 am - 12:21 pm
MYR
-
EYW
27h 12m
2 stops
Multiple Airlines Logo
2:25 pm - 8:13 am
EYW
-
MYR
17h 48m
1 stop
$271Multiple Airlines
Mon, Feb 16 - Fri, Feb 20
Multiple Airlines Logo
9:09 am - 9:06 am
MYR
-
EYW
23h 57m
2 stops
Multiple Airlines Logo
2:25 pm - 8:13 am
EYW
-
MYR
17h 48m
1 stop
$276Multiple Airlines
Wed, Feb 18 - Sun, Feb 22
Multiple Airlines Logo
11:28 am - 1:30 pm
MYR
-
EYW
26h 02m
1 stop
Multiple Airlines Logo
2:25 pm - 8:13 am
EYW
-
MYR
17h 48m
1 stop
$291Multiple Airlines
Wed, Feb 18 - Sun, Feb 22
American Airlines Logo
1:02 pm - 6:52 pm
MYR
-
EYW
5h 50m
1 stop
American Airlines Logo
4:45 pm - 9:43 pm
EYW
-
MYR
4h 58m
1 stop
$304American Airlines
Fri, May 29 - Wed, Jun 3
Multiple Airlines Logo
6:28 pm - 9:06 am
MYR
-
EYW
38h 38m
2 stops
Multiple Airlines Logo
2:35 pm - 5:33 pm
EYW
-
MYR
26h 58m
1 stop
$316Multiple Airlines
Fri, Mar 27 - Fri, Apr 3
Spirit Airlines Logo
9:09 am - 1:30 pm
MYR
-
EYW
4h 21m
1 stop
Spirit Airlines Logo
2:25 pm - 11:02 am
EYW
-
MYR
20h 37m
3 stops
$339Spirit Airlines
Mon, Feb 16 - Fri, Feb 20
Spirit Airlines Logo
9:09 am - 1:30 pm
MYR
-
EYW
4h 21m
1 stop
Spirit Airlines Logo
2:25 pm - 8:13 am
EYW
-
MYR
17h 48m
1 stop
$354Spirit Airlines
Fri, Feb 13 - Fri, Feb 20
Multiple Airlines Logo
9:09 am - 1:30 pm
MYR
-
EYW
4h 21m
1 stop
Multiple Airlines Logo
9:49 am - 8:13 am
EYW
-
MYR
22h 24m
2 stops
$375Multiple Airlines
Fri, Feb 13 - Fri, Feb 20
American Airlines Logo
1:02 pm - 6:52 pm
MYR
-
EYW
5h 50m
1 stop
American Airlines Logo
4:45 pm - 9:43 pm
EYW
-
MYR
4h 58m
1 stop
$383American Airlines
Fri, May 29 - Tue, Jun 2

Spirit Airlines flights from Myrtle Beach to Key West

Our best Spirit Airlines deals on Myrtle Beach to Key West flight tickets
Spirit Airlines
Feb 16
MYR9:09 amMyrtle Beach Intl
4h 21m
1 stop
EYW1:30 pmKey West
Feb 20
EYW2:25 pmKey West
17h 48m
1 stop
MYR8:13 amMyrtle Beach Intl
$268
Spirit Airlines
Feb 13
MYR9:09 amMyrtle Beach Intl
4h 21m
1 stop
EYW1:30 pmKey West
Feb 20
EYW2:25 pmKey West
17h 48m
1 stop
MYR8:13 amMyrtle Beach Intl
$354
Spirit Airlines
Feb 7
MYR1:07 pmMyrtle Beach Intl
22h 49m
3 stops
EYW11:56 amKey West
Feb 9
EYW2:25 pmKey West
4h 55m
1 stop
MYR7:20 pmMyrtle Beach Intl
$484

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Mar 27
MYR8:43 pmMyrtle Beach Intl
36h 23m
2 stops
EYW9:06 amKey West
Apr 3
EYW1:06 pmKey West
44h 41m
2 stops
MYR9:47 amMyrtle Beach Intl
$755
Breeze Airways
Mar 27
MYR8:43 pmMyrtle Beach Intl
36h 23m
2 stops
EYW9:06 amKey West
Apr 3
EYW1:06 pmKey West
28h 10m
3 stops
MYR5:16 pmMyrtle Beach Intl
$760
Breeze Airways
Feb 13
MYR10:40 amMyrtle Beach Intl
46h 26m
2 stops
EYW9:06 amKey West
Feb 20
EYW11:04 amKey West
27h 47m
3 stops
MYR2:51 pmMyrtle Beach Intl
$868

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 2/16

9:09 am-1:30 pm

1 stop4h 21m

Key West

Fri 2/20

2:25 pm-8:13 am

1 stop17h 48m

$268

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 2/16

9:09 am-12:21 pm

2 stops27h 12m

Key West

Fri 2/20

2:25 pm-8:13 am

1 stop17h 48m

$271

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 2/18

9:09 am-9:06 am

2 stops23h 57m

Key West

Sun 2/22

2:25 pm-8:13 am

1 stop17h 48m

$276

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 2/18

11:28 am-1:30 pm

1 stop26h 02m

Key West

Sun 2/22

2:25 pm-8:13 am

1 stop17h 48m

$291

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 5/29

1:02 pm-6:52 pm

1 stop5h 50m

Key West

Wed 6/3

4:45 pm-9:43 pm

1 stop4h 58m

$304

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 3/27

6:28 pm-9:06 am

2 stops38h 38m

Key West

Fri 4/3

2:35 pm-5:33 pm

1 stop26h 58m

$316

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 2/16

9:09 am-1:30 pm

1 stop4h 21m

Key West

Fri 2/20

2:25 pm-11:02 am

3 stops20h 37m

$339

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 2/13

9:09 am-1:30 pm

1 stop4h 21m

Key West

Fri 2/20

2:25 pm-8:13 am

1 stop17h 48m

$354

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 2/13

9:09 am-1:30 pm

1 stop4h 21m

Key West

Fri 2/20

9:49 am-8:13 am

2 stops22h 24m

$375

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 5/29

1:02 pm-6:52 pm

1 stop5h 50m

Key West

Tue 6/2

4:45 pm-9:43 pm

1 stop4h 58m

$383

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you are unable to visit Key West during the month of September, then departing from Myrtle Beach during the month May is also very affordable. Most momondo users find prices during this month for around $367.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 54% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

4h 53m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 4h 53m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 53m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,138 reviews
Search Delta flights
American AirlinesPriceFrom $263Free CancellationRating
7.2
11,216 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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