What airlines fly to Key West?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Key West from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 75% of people opting to fly with this airline when traveling to Key West. Keep in mind that there are 3 different airlines that fly to Key West on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Myrtle Beach Intl to Key West?

Spirit Airlines and American Airlines are the most popular carriers operating from Myrtle Beach Intl to Key West

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

As of December 2025, there are 2 operators available to choose from for flights from Myrtle Beach Intl Airport to Key West Airport.

How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

What documentation or ID do you need to fly to Key West Airport?

The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$114 Cheap Flights from Myrtle Beach to Key West in 2025/26

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9:09 am - 1:30 pm

MYR

EYW

4h 21m1 stop

2:25 pm - 8:13 am

EYW

MYR

17h 48m1 stop

$226Spirit Airlines

Fri, Feb 27 - Mon, Mar 2

8:15 pm - 1:30 pm

MYR

EYW

17h 15m1 stop

2:25 pm - 7:20 pm

EYW

MYR

4h 55m1 stop

$231Spirit Airlines

Thu, Jan 22 - Mon, Jan 26

9:09 am - 1:30 pm

MYR

EYW

4h 21m1 stop

2:25 pm - 8:13 am

EYW

MYR

17h 48m1 stop

$232Spirit Airlines

Sun, Feb 15 - Thu, Feb 19

6:09 pm - 10:09 am

MYR

EYW

16h 00m1 stop

2:25 pm - 7:20 pm

EYW

MYR

4h 55m1 stop

$236Multiple Airlines

Fri, Jan 23 - Mon, Jan 26

9:09 am - 1:30 pm

MYR

EYW

4h 21m1 stop

2:25 pm - 2:44 pm

EYW

MYR

24h 19m2 stops

$245Spirit Airlines

Fri, Feb 27 - Mon, Mar 2

9:09 am - 1:30 pm

MYR

EYW

4h 21m1 stop

2:25 pm - 8:13 am

EYW

MYR

17h 48m1 stop

$249Spirit Airlines

Mon, Mar 2 - Fri, Mar 6

8:15 pm - 1:30 pm

MYR

EYW

17h 15m1 stop

2:25 pm - 2:42 pm

EYW

MYR

24h 17m2 stops

$257Spirit Airlines

Thu, Jan 22 - Mon, Jan 26

5:29 pm - 9:47 pm

MYR

EYW

4h 18m1 stop

1:22 pm - 6:49 pm

EYW

MYR

5h 27m1 stop

$260American Airlines

Fri, Jan 23 - Tue, Jan 27

5:29 pm - 9:47 pm

MYR

EYW

4h 18m1 stop

12:00 pm - 6:49 pm

EYW

MYR

6h 49m2 stops

$265American Airlines

Fri, Jan 23 - Tue, Jan 27

6:09 pm - 10:09 am

MYR

EYW

16h 00m1 stop

1:06 pm - 9:03 am

EYW

MYR

19h 57m2 stops

$268Multiple Airlines

Fri, Jan 23 - Mon, Jan 26

American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets

American Airlines

Jan 23

MYR5:29 pmMyrtle Beach Intl

4h 18m

1 stop

EYW9:47 pmKey West

Jan 27

EYW1:22 pmKey West

5h 27m

1 stop

MYR6:49 pmMyrtle Beach Intl

$260

Find similar

American Airlines

Jan 23

MYR5:29 pmMyrtle Beach Intl

4h 18m

1 stop

EYW9:47 pmKey West

Jan 27

EYW12:00 pmKey West

6h 49m

2 stops

MYR6:49 pmMyrtle Beach Intl

$265

Find similar

American Airlines

Jan 23

MYR8:00 amMyrtle Beach Intl

11h 10m

2 stops

EYW7:10 pmKey West

Jan 27

EYW12:00 pmKey West

8h 54m

2 stops

MYR8:54 pmMyrtle Beach Intl

$270

Find similar

Delta flights from Myrtle Beach to Key West

Our best Delta deals on Myrtle Beach to Key West flight tickets

Delta

May 8

MYR1:05 pmMyrtle Beach Intl

6h 39m

1 stop

EYW7:44 pmKey West

May 11

EYW7:00 amKey West

5h 19m

1 stop

MYR12:19 pmMyrtle Beach Intl

$304

Find similar

Delta

Apr 13

MYR6:00 amMyrtle Beach Intl

4h 52m

1 stop

EYW10:52 amKey West

Apr 15

EYW7:35 amKey West

5h 11m

1 stop

MYR12:46 pmMyrtle Beach Intl

$497

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 2/27

9:09 am-1:30 pm

1 stop4h 21m

Key West

Mon 3/2

2:25 pm-8:13 am

1 stop17h 48m

$226

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/22

8:15 pm-1:30 pm

1 stop17h 15m

Key West

Mon 1/26

2:25 pm-7:20 pm

1 stop4h 55m

$231

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 2/15

9:09 am-1:30 pm

1 stop4h 21m

Key West

Thu 2/19

2:25 pm-8:13 am

1 stop17h 48m

$232

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 1/23

6:09 pm-10:09 am

1 stop16h 00m

Key West

Mon 1/26

2:25 pm-7:20 pm

1 stop4h 55m

$236

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 2/27

9:09 am-1:30 pm

1 stop4h 21m

Key West

Mon 3/2

2:25 pm-2:44 pm

2 stops24h 19m

$245

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 3/2

9:09 am-1:30 pm

1 stop4h 21m

Key West

Fri 3/6

2:25 pm-8:13 am

1 stop17h 48m

$249

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/22

8:15 pm-1:30 pm

1 stop17h 15m

Key West

Mon 1/26

2:25 pm-2:42 pm

2 stops24h 17m

$257

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 1/23

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Tue 1/27

1:22 pm-6:49 pm

1 stop5h 27m

$260

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 1/23

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Tue 1/27

12:00 pm-6:49 pm

2 stops6h 49m

$265

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 1/23

6:09 pm-10:09 am

1 stop16h 00m

Key West

Mon 1/26

1:06 pm-9:03 am

2 stops19h 57m

$268

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you are unable to visit Key West during the month of September, then departing from Myrtle Beach during the month August is also very affordable. Most momondo users find prices during this month for around $367.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Myrtle Beach is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $398. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Key West for around $603.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 48% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time	4h 04m
Direct flights	None

The fastest flight from Myrtle Beach to Key West takes 4h 04m

There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.

Search flight deals

How far is Myrtle Beach Intl to Key West by plane?
A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 04m by plane in normal conditions.
When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?
Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?
As of December 2025, there are 2 operators available to choose from for flights from Myrtle Beach Intl Airport to Key West Airport.
How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.
What documentation or ID do you need to fly to Key West Airport?
The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Myrtle Beach to Key West?
Based on momondo bookings for flights between Myrtle Beach and Key West, the leading airline is American Airlines, making up 79% of the total bookings. Other popular airlines include Delta with 21%.

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,019 reviews		Search Delta flights
American Airlines	PriceFrom $263	Free Cancellation	Rating 7.2 11,072 reviews		Search American Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.