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Cheap flights from Myrtle Beach to Key West from $246

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:14 pm - 12:34 pm
MYR
-
EYW
18h 20m
1 stop
Multiple Airlines Logo
2:14 pm - 12:32 pm
EYW
-
MYR
22h 18m
1 stop
$246Multiple Airlines
Mon, May 18 - Thu, May 21
Breeze Airways Logo
8:41 pm - 12:34 pm
MYR
-
EYW
15h 53m
1 stop
Breeze Airways Logo
7:53 pm - 2:06 pm
EYW
-
MYR
18h 13m
1 stop
$270Breeze Airways
Mon, Jul 13 - Thu, Jul 16
Breeze Airways Logo
6:14 pm - 12:34 pm
MYR
-
EYW
18h 20m
1 stop
Breeze Airways Logo
12:07 pm - 9:05 am
EYW
-
MYR
20h 58m
1 stop
$276Breeze Airways
Mon, May 18 - Fri, May 22
Breeze Airways Logo
6:14 pm - 12:34 pm
MYR
-
EYW
18h 20m
1 stop
Breeze Airways Logo
12:07 pm - 9:05 am
EYW
-
MYR
20h 58m
1 stop
$281Breeze Airways
Mon, May 11 - Fri, May 15
Multiple Airlines Logo
6:14 pm - 12:34 pm
MYR
-
EYW
18h 20m
1 stop
Multiple Airlines Logo
9:24 pm - 12:32 pm
EYW
-
MYR
15h 08m
2 stops
$285Multiple Airlines
Mon, May 18 - Thu, May 21
Multiple Airlines Logo
6:14 pm - 12:34 pm
MYR
-
EYW
18h 20m
1 stop
Multiple Airlines Logo
12:07 pm - 7:37 pm
EYW
-
MYR
31h 30m
2 stops
$292Multiple Airlines
Mon, May 11 - Fri, May 15
Multiple Airlines Logo
3:43 pm - 12:34 pm
MYR
-
EYW
20h 51m
2 stops
Multiple Airlines Logo
7:53 pm - 2:06 pm
EYW
-
MYR
18h 13m
1 stop
$301Multiple Airlines
Mon, Jul 13 - Thu, Jul 16
Multiple Airlines Logo
6:14 pm - 12:34 pm
MYR
-
EYW
18h 20m
1 stop
Multiple Airlines Logo
2:51 pm - 4:02 pm
EYW
-
MYR
25h 11m
2 stops
$303Multiple Airlines
Mon, May 18 - Fri, May 22
Breeze Airways Logo
4:21 pm - 10:24 am
MYR
-
EYW
18h 03m
1 stop
Breeze Airways Logo
12:05 pm - 9:05 am
EYW
-
MYR
21h 00m
1 stop
$315Breeze Airways
Sat, Jun 20 - Thu, Jun 25
Delta Logo
6:00 am - 10:53 am
MYR
-
EYW
4h 53m
1 stop
Delta Logo
7:30 am - 12:40 pm
EYW
-
MYR
5h 10m
1 stop
$316Delta
Fri, May 29 - Tue, Jun 2

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Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Jul 13
MYR8:41 pmMyrtle Beach Intl
15h 53m
1 stop
EYW12:34 pmKey West
Jul 16
EYW7:53 pmKey West
18h 13m
1 stop
MYR2:06 pmMyrtle Beach Intl
$270
Breeze Airways
May 18
MYR6:14 pmMyrtle Beach Intl
18h 20m
1 stop
EYW12:34 pmKey West
May 22
EYW12:07 pmKey West
20h 58m
1 stop
MYR9:05 amMyrtle Beach Intl
$276
Breeze Airways
May 11
MYR6:14 pmMyrtle Beach Intl
18h 20m
1 stop
EYW12:34 pmKey West
May 15
EYW12:07 pmKey West
20h 58m
1 stop
MYR9:05 amMyrtle Beach Intl
$281

American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets
American Airlines
May 13
MYR1:57 pmMyrtle Beach Intl
9h 01m
2 stops
EYW10:58 pmKey West
May 20
EYW8:05 amKey West
5h 22m
1 stop
MYR1:27 pmMyrtle Beach Intl
$339
American Airlines
May 9
MYR6:04 amMyrtle Beach Intl
7h 04m
2 stops
EYW1:08 pmKey West
May 13
EYW11:24 amKey West
11h 00m
2 stops
MYR10:24 pmMyrtle Beach Intl
$370
American Airlines
May 7
MYR6:04 amMyrtle Beach Intl
5h 12m
1 stop
EYW11:16 amKey West
May 11
EYW11:56 amKey West
6h 05m
1 stop
MYR6:01 pmMyrtle Beach Intl
$399

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 5/18

6:14 pm-12:34 pm

1 stop18h 20m

Key West

Thu 5/21

2:14 pm-12:32 pm

1 stop22h 18m

$246

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 7/13

8:41 pm-12:34 pm

1 stop15h 53m

Key West

Thu 7/16

7:53 pm-2:06 pm

1 stop18h 13m

$270

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 5/18

6:14 pm-12:34 pm

1 stop18h 20m

Key West

Fri 5/22

12:07 pm-9:05 am

1 stop20h 58m

$276

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 5/11

6:14 pm-12:34 pm

1 stop18h 20m

Key West

Fri 5/15

12:07 pm-9:05 am

1 stop20h 58m

$281

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 5/18

6:14 pm-12:34 pm

1 stop18h 20m

Key West

Thu 5/21

9:24 pm-12:32 pm

2 stops15h 08m

$285

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 5/11

6:14 pm-12:34 pm

1 stop18h 20m

Key West

Fri 5/15

12:07 pm-7:37 pm

2 stops31h 30m

$292

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 7/13

3:43 pm-12:34 pm

2 stops20h 51m

Key West

Thu 7/16

7:53 pm-2:06 pm

1 stop18h 13m

$301

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 5/18

6:14 pm-12:34 pm

1 stop18h 20m

Key West

Fri 5/22

2:51 pm-4:02 pm

2 stops25h 11m

$303

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 6/20

4:21 pm-10:24 am

1 stop18h 03m

Key West

Thu 6/25

12:05 pm-9:05 am

1 stop21h 00m

$315
Quickest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 5/29

6:00 am-10:53 am

1 stop4h 53m

Key West

Tue 6/2

7:30 am-12:40 pm

1 stop5h 10m

$316

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $335. If you are unable to visit Key West during the month of January, then departing from Myrtle Beach during the month June is also very affordable. Most momondo users find prices during this month for around $368.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 14% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

6h 19m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 6h 19m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Key West

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 6h 19m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,463 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,681 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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