What is the cheapest airline that flies from Myrtle Beach Intl to Key West?

Spirit Airlines, Delta, and Breeze Airways are the most popular carriers operating from Myrtle Beach Intl to Key West

What airlines fly to Key West?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Key West from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 75% of people opting to fly with this airline when traveling to Key West. Keep in mind that there are 3 different airlines that fly to Key West on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

As of December 2025, there are 2 operators available to choose from for flights from Myrtle Beach Intl Airport to Key West Airport.

How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

What documentation or ID do you need to fly to Key West Airport?

The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$116 Cheap Flights from Myrtle Beach to Key West in 2025/26

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Cheap round-trip flights

Enter your travel dates to find the best prices.

5:29 pm - 9:47 pm

MYR

EYW

4h 18m1 stop

7:08 am - 1:23 pm

EYW

MYR

6h 15m1 stop

$209American Airlines

Thu, Jan 8 - Mon, Jan 12

1:53 pm - 11:56 pm

MYR

EYW

10h 03m2 stops

7:08 am - 11:35 am

EYW

MYR

4h 27m1 stop

$214American Airlines

Thu, Jan 8 - Mon, Jan 12

1:53 pm - 11:56 pm

MYR

EYW

10h 03m2 stops

4:37 pm - 11:57 pm

EYW

MYR

7h 20m2 stops

$219American Airlines

Fri, Jan 23 - Tue, Jan 27

12:05 pm - 6:01 pm

MYR

EYW

5h 56m1 stop

6:53 pm - 11:38 pm

EYW

MYR

4h 45m1 stop

$239American Airlines

Wed, Jan 28 - Sat, Jan 31

5:29 pm - 9:47 pm

MYR

EYW

4h 18m1 stop

6:06 am - 1:23 pm

EYW

MYR

7h 17m2 stops

$244American Airlines

Wed, Jan 21 - Sat, Jan 24

1:53 pm - 11:56 pm

MYR

EYW

10h 03m2 stops

6:06 am - 1:23 pm

EYW

MYR

7h 17m2 stops

$249American Airlines

Thu, Jan 8 - Mon, Jan 12

5:29 pm - 9:47 pm

MYR

EYW

4h 18m1 stop

7:08 am - 1:23 pm

EYW

MYR

6h 15m1 stop

$251American Airlines

Tue, Jan 6 - Wed, Jan 7

1:53 pm - 11:56 pm

MYR

EYW

10h 03m2 stops

7:08 am - 1:23 pm

EYW

MYR

6h 15m1 stop

$256American Airlines

Tue, Jan 6 - Wed, Jan 7

1:53 pm - 11:56 pm

MYR

EYW

10h 03m2 stops

6:06 am - 1:23 pm

EYW

MYR

7h 17m2 stops

$261American Airlines

Tue, Jan 6 - Wed, Jan 7

5:29 pm - 9:47 pm

MYR

EYW

4h 18m1 stop

7:15 am - 11:35 am

EYW

MYR

4h 20m1 stop

$264American Airlines

Wed, Jan 21 - Sat, Jan 24

American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets

American Airlines

Jan 8

MYR5:29 pmMyrtle Beach Intl

4h 18m

1 stop

EYW9:47 pmKey West

Jan 12

EYW7:08 amKey West

6h 15m

1 stop

MYR1:23 pmMyrtle Beach Intl

$209

Find similar

American Airlines

Jan 8

MYR1:53 pmMyrtle Beach Intl

10h 03m

2 stops

EYW11:56 pmKey West

Jan 12

EYW7:08 amKey West

4h 27m

1 stop

MYR11:35 amMyrtle Beach Intl

$214

Find similar

American Airlines

Jan 23

MYR1:53 pmMyrtle Beach Intl

10h 03m

2 stops

EYW11:56 pmKey West

Jan 27

EYW4:37 pmKey West

7h 20m

2 stops

MYR11:57 pmMyrtle Beach Intl

$219

Find similar

United Airlines flights from Myrtle Beach to Key West

Our best United Airlines deals on Myrtle Beach to Key West flight tickets

United Airlines

Feb 14

MYR12:26 pmMyrtle Beach Intl

33h 43m

2 stops

EYW10:09 pmKey West

Feb 16

EYW6:40 pmKey West

17h 39m

2 stops

MYR12:19 pmMyrtle Beach Intl

$992

Find similar

United Airlines

Feb 6

MYR1:25 pmMyrtle Beach Intl

25h 52m

2 stops

EYW3:17 pmKey West

Feb 10

EYW4:15 pmKey West

20h 26m

2 stops

MYR12:41 pmMyrtle Beach Intl

$1,016

Find similar

United Airlines

Mar 9

MYR6:05 pmMyrtle Beach Intl

22h 31m

2 stops

EYW4:36 pmKey West

Mar 13

EYW4:05 pmKey West

20h 11m

3 stops

MYR12:16 pmMyrtle Beach Intl

$1,017

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/8

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Mon 1/12

7:08 am-1:23 pm

1 stop6h 15m

$209

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/8

1:53 pm-11:56 pm

2 stops10h 03m

Key West

Mon 1/12

7:08 am-11:35 am

1 stop4h 27m

$214

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 1/23

1:53 pm-11:56 pm

2 stops10h 03m

Key West

Tue 1/27

4:37 pm-11:57 pm

2 stops7h 20m

$219

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 1/28

12:05 pm-6:01 pm

1 stop5h 56m

Key West

Sat 1/31

6:53 pm-11:38 pm

1 stop4h 45m

$239

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 1/21

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Sat 1/24

6:06 am-1:23 pm

2 stops7h 17m

$244

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/8

1:53 pm-11:56 pm

2 stops10h 03m

Key West

Mon 1/12

6:06 am-1:23 pm

2 stops7h 17m

$249

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 1/6

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Wed 1/7

7:08 am-1:23 pm

1 stop6h 15m

$251

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 1/6

1:53 pm-11:56 pm

2 stops10h 03m

Key West

Wed 1/7

7:08 am-1:23 pm

1 stop6h 15m

$256

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 1/6

1:53 pm-11:56 pm

2 stops10h 03m

Key West

Wed 1/7

6:06 am-1:23 pm

2 stops7h 17m

$261

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 1/21

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Sat 1/24

7:15 am-11:35 am

1 stop4h 20m

$264

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you are unable to visit Key West during the month of September, then departing from Myrtle Beach during the month August is also very affordable. Most momondo users find prices during this month for around $367.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Myrtle Beach is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $398. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Key West for around $603.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is in the afternoon. momondo users have found flights departing from Myrtle Beach to Key West in the afternoon for as low as $445. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the morning, with an average ticket price of $488. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 11% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time	5h 21m
Direct flights	None

The fastest flight from Myrtle Beach to Key West takes 5h 21m

There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.

Search flight deals

How far is Myrtle Beach Intl to Key West by plane?
A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 5h 21m by plane in normal conditions.
When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?
Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?
As of December 2025, there are 2 operators available to choose from for flights from Myrtle Beach Intl Airport to Key West Airport.
How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.
What documentation or ID do you need to fly to Key West Airport?
The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Myrtle Beach to Key West?
Based on momondo bookings for flights between Myrtle Beach and Key West, the leading airline is American Airlines, making up 80% of the total bookings. Other popular airlines include Delta with 20%.

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,005 reviews		Search Delta flights
American Airlines	PriceFrom $279	Free Cancellation	Rating 7.2 11,054 reviews		Search American Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.