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Cheap flights from Myrtle Beach to Key West from $138

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 8/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
9:07 pm - 12:31 pmMYR  Myrtle Beach Intl-EYW Key West
15h 24m1 stop Tampa
Breeze Airways Logo
7:53 pm - 2:06 pmEYW  Key West-MYR Myrtle Beach Intl
18h 13m1 stop Tampa
$221Breeze Airways
Sun, Aug 23 - Thu, Aug 27
Breeze Airways Logo
4:21 pm - 7:13 pmMYR  Myrtle Beach Intl-EYW Key West
26h 52m1 stop Tampa
Breeze Airways Logo
7:53 pm - 2:06 pmEYW  Key West-MYR Myrtle Beach Intl
18h 13m1 stop Tampa
$221Breeze Airways
Sat, Aug 22 - Thu, Aug 27
Multiple Airlines Logo
4:21 pm - 7:13 pmMYR  Myrtle Beach Intl-EYW Key West
26h 52m1 stop Tampa
Multiple Airlines Logo
10:04 am - 8:52 amEYW  Key West-MYR Myrtle Beach Intl
22h 48m2 stops Tampa Philadelphia
$232Multiple Airlines
Sat, Sep 5 - Sat, Sep 12
Breeze Airways Logo
9:07 pm - 12:31 pmMYR  Myrtle Beach Intl-EYW Key West
15h 24m1 stop Tampa
Breeze Airways Logo
11:04 am - 5:45 pmEYW  Key West-MYR Myrtle Beach Intl
6h 41m2 stops Tampa Fort Lauderdale
$238Breeze Airways
Sun, Aug 23 - Thu, Aug 27
Delta Logo
6:00 am - 10:46 amMYR  Myrtle Beach Intl-EYW Key West
4h 46m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:19 pm - 11:28 pmEYW  Key West-MYR Myrtle Beach Intl
5h 09m1 stop Atlanta Hartsfield-Jackson
$317Delta
Mon, Sep 14 - Tue, Sep 22
American Airlines Logo
12:14 pm - 4:18 pmMYR  Myrtle Beach Intl-EYW Key West
4h 04m1 stop Charlotte Douglas
American Airlines Logo
4:50 pm - 10:38 pmEYW  Key West-MYR Myrtle Beach Intl
5h 48m1 stop Charlotte Douglas
$349American Airlines
Fri, Aug 21 - Tue, Aug 25
Delta Logo
2:20 pm - 8:00 pmMYR  Myrtle Beach Intl-EYW Key West
5h 40m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:19 pm - 11:28 pmEYW  Key West-MYR Myrtle Beach Intl
5h 09m1 stop Atlanta Hartsfield-Jackson
$361Delta
Fri, Sep 18 - Tue, Sep 22
American Airlines Logo
12:02 pm - 5:56 pmMYR  Myrtle Beach Intl-EYW Key West
5h 54m1 stop Charlotte Douglas
American Airlines Logo
1:52 pm - 9:05 pmEYW  Key West-MYR Myrtle Beach Intl
7h 13m1 stop Charlotte Douglas
$378American Airlines
Mon, Nov 2 - Sat, Nov 7
American Airlines Logo
8:07 am - 3:06 pmMYR  Myrtle Beach Intl-EYW Key West
6h 59m1 stop Charlotte Douglas
American Airlines Logo
1:52 pm - 9:05 pmEYW  Key West-MYR Myrtle Beach Intl
7h 13m1 stop Charlotte Douglas
$378American Airlines
Mon, Nov 2 - Sat, Nov 7
Delta Logo
6:00 am - 10:50 amMYR  Myrtle Beach Intl-EYW Key West
4h 50m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:40 am - 1:33 pmEYW  Key West-MYR Myrtle Beach Intl
5h 53m1 stop Atlanta Hartsfield-Jackson
$439Delta
Mon, Sep 7 - Mon, Sep 14

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American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets
American Airlines
Aug 21
MYR12:14 pmMyrtle Beach Intl
4h 04m
1 stop
EYW4:18 pmKey West
Aug 25
EYW4:50 pmKey West
5h 48m
1 stop
MYR10:38 pmMyrtle Beach Intl
$349
American Airlines
Nov 2
MYR8:07 amMyrtle Beach Intl
6h 59m
1 stop
EYW3:06 pmKey West
Nov 7
EYW1:52 pmKey West
7h 13m
1 stop
MYR9:05 pmMyrtle Beach Intl
$378
American Airlines
Sep 23
MYR12:10 pmMyrtle Beach Intl
5h 45m
1 stop
EYW5:55 pmKey West
Sep 26
EYW1:47 pmKey West
7h 21m
2 stops
MYR9:08 pmMyrtle Beach Intl
$380

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Aug 22
MYR4:21 pmMyrtle Beach Intl
26h 52m
1 stop
EYW7:13 pmKey West
Aug 27
EYW7:53 pmKey West
18h 13m
1 stop
MYR2:06 pmMyrtle Beach Intl
$221
Breeze Airways
Sep 5
MYR4:21 pmMyrtle Beach Intl
26h 52m
1 stop
EYW7:13 pmKey West
Sep 12
EYW10:04 amKey West
26h 10m
1 stop
MYR12:14 pmMyrtle Beach Intl
$238
Breeze Airways
Aug 22
MYR4:21 pmMyrtle Beach Intl
26h 52m
1 stop
EYW7:13 pmKey West
Aug 27
EYW11:04 amKey West
6h 41m
2 stops
MYR5:45 pmMyrtle Beach Intl
$255

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sun 8/23

9:07 pm-12:31 pm

1 stop15h 24m

Key West

Thu 8/27

7:53 pm-2:06 pm

1 stop18h 13m

$221

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sat 8/22

4:21 pm-7:13 pm

1 stop26h 52m

Key West

Thu 8/27

7:53 pm-2:06 pm

1 stop18h 13m

$221

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sat 9/5

4:21 pm-7:13 pm

1 stop26h 52m

Key West

Sat 9/12

10:04 am-8:52 am

2 stops22h 48m

$232

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sun 8/23

9:07 pm-12:31 pm

1 stop15h 24m

Key West

Thu 8/27

11:04 am-5:45 pm

2 stops6h 41m

$238

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Mon 9/14

6:00 am-10:46 am

1 stop4h 46m

Key West

Tue 9/22

6:19 pm-11:28 pm

1 stop5h 09m

$317
Quickest round-trip

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Fri 8/21

12:14 pm-4:18 pm

1 stop4h 04m

Key West

Tue 8/25

4:50 pm-10:38 pm

1 stop5h 48m

$349

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Fri 9/18

2:20 pm-8:00 pm

1 stop5h 40m

Key West

Tue 9/22

6:19 pm-11:28 pm

1 stop5h 09m

$361

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Mon 11/2

12:02 pm-5:56 pm

1 stop5h 54m

Key West

Sat 11/7

1:52 pm-9:05 pm

1 stop7h 13m

$378

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Mon 11/2

8:07 am-3:06 pm

1 stop6h 59m

Key West

Sat 11/7

1:52 pm-9:05 pm

1 stop7h 13m

$378

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Mon 9/7

6:00 am-10:50 am

1 stop4h 50m

Key West

Mon 9/14

7:40 am-1:33 pm

1 stop5h 53m

$439

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $335. If you are unable to visit Key West during the month of January, then departing from Myrtle Beach during the month September is also very affordable. Most momondo users find prices during this month for around $377.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 14% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

7h 00m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 7h 00m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Key West

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 7h 00m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $302Free CancellationRating
7.8
8,505 reviews
Search Delta flights
American AirlinesPriceFrom $302Free CancellationRating
7.1
11,901 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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