Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Myrtle Beach to Key West from $122

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 5/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
9:07 pm - 12:31 pm
MYR
-
EYW
15h 24m
1 stop
Breeze Airways Logo
1:11 pm - 11:39 am
EYW
-
MYR
22h 28m
1 stop
$271Breeze Airways
Sun, Aug 23 - Fri, Aug 28
Breeze Airways Logo
6:14 pm - 12:34 pm
MYR
-
EYW
18h 20m
1 stop
Breeze Airways Logo
1:14 pm - 11:39 am
EYW
-
MYR
22h 25m
1 stop
$281Breeze Airways
Mon, Jun 8 - Tue, Jun 16
Multiple Airlines Logo
9:52 pm - 11:06 am
MYR
-
EYW
37h 14m
2 stops
Multiple Airlines Logo
1:14 pm - 11:39 am
EYW
-
MYR
22h 25m
1 stop
$287Multiple Airlines
Mon, Jun 8 - Tue, Jun 16
Breeze Airways Logo
6:25 pm - 10:27 am
MYR
-
EYW
16h 02m
2 stops
Breeze Airways Logo
1:11 pm - 11:39 am
EYW
-
MYR
22h 28m
1 stop
$296Breeze Airways
Sun, Aug 23 - Fri, Aug 28
Delta Logo
6:00 am - 10:53 am
MYR
-
EYW
4h 53m
1 stop
Delta Logo
6:24 pm - 11:59 pm
EYW
-
MYR
5h 35m
1 stop
$303Delta
Tue, Jun 2 - Tue, Jun 9
American Airlines Logo
2:45 pm - 9:47 pm
MYR
-
EYW
7h 02m
1 stop
American Airlines Logo
4:53 pm - 11:55 pm
EYW
-
MYR
7h 02m
1 stop
$306American Airlines
Mon, Nov 2 - Sat, Nov 7
Multiple Airlines Logo
6:12 pm - 9:24 am
MYR
-
EYW
15h 12m
1 stop
Multiple Airlines Logo
1:28 pm - 5:52 pm
EYW
-
MYR
28h 24m
1 stop
$312Multiple Airlines
Fri, Oct 16 - Thu, Oct 22
Breeze Airways Logo
9:07 pm - 12:31 pm
MYR
-
EYW
15h 24m
1 stop
Breeze Airways Logo
11:04 am - 3:14 pm
EYW
-
MYR
4h 10m
1 stop
$314Breeze Airways
Sun, Jun 7 - Thu, Jun 11
Delta Logo
6:00 am - 10:53 am
MYR
-
EYW
4h 53m
1 stop
Delta Logo
6:24 pm - 11:59 pm
EYW
-
MYR
5h 35m
1 stop
$316Delta
Tue, Jun 2 - Tue, Jun 9
Delta Logo
6:00 am - 10:58 am
MYR
-
EYW
4h 58m
1 stop
Delta Logo
6:00 pm - 11:39 pm
EYW
-
MYR
5h 39m
1 stop
$319Delta
Sun, Sep 6 - Sun, Sep 13

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Delta flights from Myrtle Beach to Key West

Our best Delta deals on Myrtle Beach to Key West flight tickets
Delta
Jun 2
MYR6:00 amMyrtle Beach Intl
4h 53m
1 stop
EYW10:53 amKey West
Jun 9
EYW6:24 pmKey West
5h 35m
1 stop
MYR11:59 pmMyrtle Beach Intl
$303
Delta
Jun 2
MYR6:00 amMyrtle Beach Intl
4h 53m
1 stop
EYW10:53 amKey West
Jun 9
EYW6:24 pmKey West
5h 35m
1 stop
MYR11:59 pmMyrtle Beach Intl
$316
Delta
Sep 6
MYR6:00 amMyrtle Beach Intl
4h 58m
1 stop
EYW10:58 amKey West
Sep 13
EYW6:00 pmKey West
5h 39m
1 stop
MYR11:39 pmMyrtle Beach Intl
$319

American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets
American Airlines
Nov 2
MYR2:45 pmMyrtle Beach Intl
7h 02m
1 stop
EYW9:47 pmKey West
Nov 7
EYW4:53 pmKey West
7h 02m
1 stop
MYR11:55 pmMyrtle Beach Intl
$306
American Airlines
Jul 6
MYR6:50 amMyrtle Beach Intl
5h 24m
1 stop
EYW12:14 pmKey West
Jul 13
EYW1:01 pmKey West
7h 02m
1 stop
MYR8:03 pmMyrtle Beach Intl
$368
American Airlines
Nov 2
MYR9:09 amMyrtle Beach Intl
7h 30m
2 stops
EYW4:39 pmKey West
Nov 7
EYW4:53 pmKey West
7h 02m
1 stop
MYR11:55 pmMyrtle Beach Intl
$370

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 8/23

9:07 pm-12:31 pm

1 stop15h 24m

Key West

Fri 8/28

1:11 pm-11:39 am

1 stop22h 28m

$271

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 6/8

6:14 pm-12:34 pm

1 stop18h 20m

Key West

Tue 6/16

1:14 pm-11:39 am

1 stop22h 25m

$281

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 6/8

9:52 pm-11:06 am

2 stops37h 14m

Key West

Tue 6/16

1:14 pm-11:39 am

1 stop22h 25m

$287

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 8/23

6:25 pm-10:27 am

2 stops16h 02m

Key West

Fri 8/28

1:11 pm-11:39 am

1 stop22h 28m

$296
Quickest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 6/2

6:00 am-10:53 am

1 stop4h 53m

Key West

Tue 6/9

6:24 pm-11:59 pm

1 stop5h 35m

$303

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 11/2

2:45 pm-9:47 pm

1 stop7h 02m

Key West

Sat 11/7

4:53 pm-11:55 pm

1 stop7h 02m

$306

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 10/16

6:12 pm-9:24 am

1 stop15h 12m

Key West

Thu 10/22

1:28 pm-5:52 pm

1 stop28h 24m

$312

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 6/7

9:07 pm-12:31 pm

1 stop15h 24m

Key West

Thu 6/11

11:04 am-3:14 pm

1 stop4h 10m

$314

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 6/2

6:00 am-10:53 am

1 stop4h 53m

Key West

Tue 6/9

6:24 pm-11:59 pm

1 stop5h 35m

$316

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 9/6

6:00 am-10:58 am

1 stop4h 58m

Key West

Sun 9/13

6:00 pm-11:39 pm

1 stop5h 39m

$319

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $335. If you are unable to visit Key West during the month of January, then departing from Myrtle Beach during the month June is also very affordable. Most momondo users find prices during this month for around $368.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 14% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

4h 53m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 4h 53m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Key West

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 53m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,459 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,669 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 6/6
Sat 6/13
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States