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Cheap flights from Myrtle Beach to Key West from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:05 pm - 12:26 pm
MYR
-
EYW
24h 21m
1 stop
Multiple Airlines Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$243Multiple Airlines
Sun, Mar 29 - Sun, Apr 5
American Airlines Logo
6:01 am - 12:01 pm
MYR
-
EYW
6h 00m
1 stop
American Airlines Logo
6:34 pm - 10:56 pm
EYW
-
MYR
4h 22m
1 stop
$251American Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
12:05 pm - 12:26 pm
MYR
-
EYW
24h 21m
1 stop
Multiple Airlines Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$254Multiple Airlines
Sun, Mar 22 - Thu, Mar 26
American Airlines Logo
6:54 am - 4:49 pm
MYR
-
EYW
9h 55m
2 stops
American Airlines Logo
6:34 pm - 10:56 pm
EYW
-
MYR
4h 22m
1 stop
$256American Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
6:28 pm - 1:37 pm
MYR
-
EYW
19h 09m
1 stop
Multiple Airlines Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$259Multiple Airlines
Thu, Mar 26 - Thu, Apr 2
Multiple Airlines Logo
6:18 pm - 12:21 pm
MYR
-
EYW
18h 03m
1 stop
Multiple Airlines Logo
1:06 pm - 11:50 am
EYW
-
MYR
22h 44m
1 stop
$265Multiple Airlines
Mon, Apr 27 - Fri, May 1
Breeze Airways Logo
6:18 pm - 12:21 pm
MYR
-
EYW
18h 03m
1 stop
Breeze Airways Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$268Breeze Airways
Mon, Apr 6 - Thu, Apr 9
Breeze Airways Logo
6:18 pm - 12:21 pm
MYR
-
EYW
18h 03m
1 stop
Breeze Airways Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$269Breeze Airways
Mon, Apr 6 - Thu, Apr 9
Multiple Airlines Logo
7:51 pm - 12:21 pm
MYR
-
EYW
16h 30m
2 stops
Multiple Airlines Logo
1:06 pm - 11:50 am
EYW
-
MYR
22h 44m
1 stop
$270Multiple Airlines
Mon, Apr 27 - Fri, May 1
Multiple Airlines Logo
6:18 pm - 12:21 pm
MYR
-
EYW
18h 03m
1 stop
Multiple Airlines Logo
12:06 pm - 9:41 am
EYW
-
MYR
21h 35m
1 stop
$271Multiple Airlines
Mon, Apr 20 - Fri, Apr 24

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Apr 6
MYR6:18 pmMyrtle Beach Intl
18h 03m
1 stop
EYW12:21 pmKey West
Apr 9
EYW9:46 amKey West
4h 36m
1 stop
MYR2:22 pmMyrtle Beach Intl
$268
Breeze Airways
Apr 6
MYR6:18 pmMyrtle Beach Intl
18h 03m
1 stop
EYW12:21 pmKey West
Apr 9
EYW9:46 amKey West
4h 36m
1 stop
MYR2:22 pmMyrtle Beach Intl
$269
Breeze Airways
Mar 2
MYR6:18 pmMyrtle Beach Intl
18h 03m
1 stop
EYW12:21 pmKey West
Mar 5
EYW9:46 amKey West
24h 14m
1 stop
MYR10:00 amMyrtle Beach Intl
$280

American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets
American Airlines
Mar 17
MYR6:01 amMyrtle Beach Intl
6h 00m
1 stop
EYW12:01 pmKey West
Mar 24
EYW6:34 pmKey West
4h 22m
1 stop
MYR10:56 pmMyrtle Beach Intl
$251
American Airlines
Mar 17
MYR6:54 amMyrtle Beach Intl
9h 55m
2 stops
EYW4:49 pmKey West
Mar 24
EYW6:34 pmKey West
4h 22m
1 stop
MYR10:56 pmMyrtle Beach Intl
$256
American Airlines
May 9
MYR6:30 pmMyrtle Beach Intl
4h 06m
1 stop
EYW10:36 pmKey West
May 14
EYW4:20 pmKey West
6h 04m
1 stop
MYR10:24 pmMyrtle Beach Intl
$295

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 3/29

12:05 pm-12:26 pm

1 stop24h 21m

Key West

Sun 4/5

9:46 am-2:22 pm

1 stop4h 36m

$243

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/17

6:01 am-12:01 pm

1 stop6h 00m

Key West

Tue 3/24

6:34 pm-10:56 pm

1 stop4h 22m

$251

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 3/22

12:05 pm-12:26 pm

1 stop24h 21m

Key West

Thu 3/26

9:46 am-2:22 pm

1 stop4h 36m

$254

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/17

6:54 am-4:49 pm

2 stops9h 55m

Key West

Tue 3/24

6:34 pm-10:56 pm

1 stop4h 22m

$256

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 3/26

6:28 pm-1:37 pm

1 stop19h 09m

Key West

Thu 4/2

9:46 am-2:22 pm

1 stop4h 36m

$259

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 4/27

6:18 pm-12:21 pm

1 stop18h 03m

Key West

Fri 5/1

1:06 pm-11:50 am

1 stop22h 44m

$265

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 4/6

6:18 pm-12:21 pm

1 stop18h 03m

Key West

Thu 4/9

9:46 am-2:22 pm

1 stop4h 36m

$268

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 4/6

6:18 pm-12:21 pm

1 stop18h 03m

Key West

Thu 4/9

9:46 am-2:22 pm

1 stop4h 36m

$269

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 4/27

7:51 pm-12:21 pm

2 stops16h 30m

Key West

Fri 5/1

1:06 pm-11:50 am

1 stop22h 44m

$270

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 4/20

6:18 pm-12:21 pm

1 stop18h 03m

Key West

Fri 4/24

12:06 pm-9:41 am

1 stop21h 35m

$271

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $359. If you are unable to visit Key West during the month of January, then departing from Myrtle Beach during the month September is also very affordable. Most momondo users find prices during this month for around $366.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 24% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

5h 12m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 5h 12m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 5h 12m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,236 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,339 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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