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Cheap flights from Myrtle Beach to Key West from $154

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 2/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:28 pm - 11:30 am
MYR
-
EYW
17h 02m
1 stop
Spirit Airlines Logo
12:25 pm - 5:33 pm
EYW
-
MYR
5h 08m
1 stop
$208Spirit Airlines
Tue, Mar 17 - Tue, Mar 31
Multiple Airlines Logo
9:49 pm - 9:06 am
MYR
-
EYW
35h 17m
2 stops
Multiple Airlines Logo
12:25 pm - 5:33 pm
EYW
-
MYR
5h 08m
1 stop
$235Multiple Airlines
Tue, Mar 17 - Tue, Mar 31
Spirit Airlines Logo
6:28 pm - 11:30 am
MYR
-
EYW
17h 02m
1 stop
Spirit Airlines Logo
12:25 pm - 5:33 pm
EYW
-
MYR
5h 08m
1 stop
$236Spirit Airlines
Wed, Mar 25 - Tue, Mar 31
Multiple Airlines Logo
12:39 pm - 12:26 pm
MYR
-
EYW
23h 47m
1 stop
Multiple Airlines Logo
2:25 pm - 8:13 am
EYW
-
MYR
17h 48m
1 stop
$240Multiple Airlines
Sun, Mar 1 - Thu, Mar 5
Multiple Airlines Logo
6:18 pm - 12:21 pm
MYR
-
EYW
18h 03m
1 stop
Multiple Airlines Logo
1:06 pm - 10:59 am
EYW
-
MYR
21h 53m
1 stop
$247Multiple Airlines
Mon, Feb 23 - Fri, Feb 27
Spirit Airlines Logo
9:09 am - 1:30 pm
MYR
-
EYW
4h 21m
1 stop
Spirit Airlines Logo
2:35 pm - 5:33 pm
EYW
-
MYR
26h 58m
1 stop
$253Spirit Airlines
Mon, Mar 9 - Mon, Mar 16
Multiple Airlines Logo
6:18 pm - 12:21 pm
MYR
-
EYW
18h 03m
1 stop
Multiple Airlines Logo
1:06 pm - 8:58 am
EYW
-
MYR
19h 52m
2 stops
$260Multiple Airlines
Mon, Feb 23 - Fri, Feb 27
Multiple Airlines Logo
6:14 pm - 12:34 pm
MYR
-
EYW
18h 20m
1 stop
Multiple Airlines Logo
12:10 pm - 11:48 am
EYW
-
MYR
23h 38m
1 stop
$263Multiple Airlines
Mon, May 11 - Fri, May 15
Multiple Airlines Logo
12:39 pm - 12:26 pm
MYR
-
EYW
23h 47m
1 stop
Multiple Airlines Logo
2:25 pm - 8:13 am
EYW
-
MYR
17h 48m
1 stop
$266Multiple Airlines
Sun, Feb 22 - Thu, Feb 26
Multiple Airlines Logo
10:30 am - 12:26 pm
MYR
-
EYW
25h 56m
1 stop
Multiple Airlines Logo
2:25 pm - 8:13 am
EYW
-
MYR
17h 48m
1 stop
$267Multiple Airlines
Sun, Mar 1 - Mon, Mar 9

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Feb 23
MYR6:18 pmMyrtle Beach Intl
18h 03m
1 stop
EYW12:21 pmKey West
Feb 26
EYW9:46 amKey West
24h 14m
1 stop
MYR10:00 amMyrtle Beach Intl
$274
Breeze Airways
Feb 19
MYR5:53 pmMyrtle Beach Intl
15h 16m
1 stop
EYW9:09 amKey West
Feb 22
EYW9:46 amKey West
24h 14m
1 stop
MYR10:00 amMyrtle Beach Intl
$415
Breeze Airways
Feb 23
MYR10:40 amMyrtle Beach Intl
25h 41m
2 stops
EYW12:21 pmKey West
Feb 27
EYW1:06 pmKey West
28h 10m
3 stops
MYR5:16 pmMyrtle Beach Intl
$665

Spirit Airlines flights from Myrtle Beach to Key West

Our best Spirit Airlines deals on Myrtle Beach to Key West flight tickets
Spirit Airlines
Mar 17
MYR6:28 pmMyrtle Beach Intl
17h 02m
1 stop
EYW11:30 amKey West
Mar 31
EYW12:25 pmKey West
5h 08m
1 stop
MYR5:33 pmMyrtle Beach Intl
$202
Spirit Airlines
Mar 17
MYR6:28 pmMyrtle Beach Intl
17h 02m
1 stop
EYW11:30 amKey West
Mar 31
EYW12:25 pmKey West
5h 08m
1 stop
MYR5:33 pmMyrtle Beach Intl
$208
Spirit Airlines
Mar 25
MYR6:28 pmMyrtle Beach Intl
17h 02m
1 stop
EYW11:30 amKey West
Mar 31
EYW12:25 pmKey West
5h 08m
1 stop
MYR5:33 pmMyrtle Beach Intl
$236

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 10, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/17

6:28 pm-11:30 am

1 stop17h 02m

Key West

Tue 3/31

12:25 pm-5:33 pm

1 stop5h 08m

$208

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/17

9:49 pm-9:06 am

2 stops35h 17m

Key West

Tue 3/31

12:25 pm-5:33 pm

1 stop5h 08m

$235

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 3/25

6:28 pm-11:30 am

1 stop17h 02m

Key West

Tue 3/31

12:25 pm-5:33 pm

1 stop5h 08m

$236

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 3/1

12:39 pm-12:26 pm

1 stop23h 47m

Key West

Thu 3/5

2:25 pm-8:13 am

1 stop17h 48m

$240

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 2/23

6:18 pm-12:21 pm

1 stop18h 03m

Key West

Fri 2/27

1:06 pm-10:59 am

1 stop21h 53m

$247

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 3/9

9:09 am-1:30 pm

1 stop4h 21m

Key West

Mon 3/16

2:35 pm-5:33 pm

1 stop26h 58m

$253

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 2/23

6:18 pm-12:21 pm

1 stop18h 03m

Key West

Fri 2/27

1:06 pm-8:58 am

2 stops19h 52m

$260

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 5/11

6:14 pm-12:34 pm

1 stop18h 20m

Key West

Fri 5/15

12:10 pm-11:48 am

1 stop23h 38m

$263

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 2/22

12:39 pm-12:26 pm

1 stop23h 47m

Key West

Thu 2/26

2:25 pm-8:13 am

1 stop17h 48m

$266

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 3/1

10:30 am-12:26 pm

1 stop25h 56m

Key West

Mon 3/9

2:25 pm-8:13 am

1 stop17h 48m

$267

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $359. If you are unable to visit Key West during the month of January, then departing from Myrtle Beach during the month September is also very affordable. Most momondo users find prices during this month for around $366.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 53% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

4h 21m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 4h 21m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 21m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,178 reviews
Search Delta flights
American AirlinesPriceFrom $263Free CancellationRating
7.2
11,259 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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