Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Myrtle Beach to Key West from $117

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 12/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Myrtle Beach to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
8:15 pm - 1:30 pmMYR-EYW
17h 15m1 stop
Spirit Airlines Logo
12:15 pm - 7:20 pmEYW-MYR
7h 05m1 stop
$227Spirit Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
Spirit Airlines Logo
9:54 am - 1:30 pmMYR-EYW
27h 36m1 stop
Spirit Airlines Logo
12:20 pm - 6:08 pmEYW-MYR
5h 48m1 stop
$231Spirit Airlines
Find Deal
Sun, Jan 4 - Tue, Jan 6
Spirit Airlines Logo
8:15 pm - 1:30 pmMYR-EYW
17h 15m1 stop
Spirit Airlines Logo
12:15 pm - 7:20 pmEYW-MYR
7h 05m1 stop
$232Spirit Airlines
Find Deal
Sun, Feb 1 - Thu, Feb 5
Spirit Airlines Logo
8:15 pm - 1:30 pmMYR-EYW
17h 15m1 stop
Spirit Airlines Logo
12:15 pm - 7:20 pmEYW-MYR
7h 05m1 stop
$233Spirit Airlines
Find Deal
Thu, Jan 29 - Sun, Feb 1
Spirit Airlines Logo
9:54 am - 1:30 pmMYR-EYW
27h 36m1 stop
Spirit Airlines Logo
12:20 pm - 6:08 pmEYW-MYR
5h 48m1 stop
$234Spirit Airlines
Find Deal
Tue, Dec 23 - Sun, Dec 28
Multiple Airlines Logo
6:09 pm - 10:09 amMYR-EYW
16h 00m1 stop
Multiple Airlines Logo
2:25 pm - 7:20 pmEYW-MYR
4h 55m1 stop
$236Multiple Airlines
Find Deal
Fri, Jan 23 - Mon, Jan 26
American Airlines Logo
3:18 pm - 10:43 pmMYR-EYW
7h 25m1 stop
American Airlines Logo
4:40 pm - 10:34 pmEYW-MYR
5h 54m1 stop
$239American Airlines
Find Deal
Sun, Feb 15 - Thu, Feb 19
American Airlines Logo
12:05 pm - 6:01 pmMYR-EYW
5h 56m1 stop
American Airlines Logo
6:43 pm - 11:57 pmEYW-MYR
5h 14m1 stop
$244American Airlines
Find Deal
Sun, Jan 18 - Tue, Feb 10
American Airlines Logo
5:29 pm - 9:47 pmMYR-EYW
4h 18m1 stop
American Airlines Logo
6:20 pm - 10:56 pmEYW-MYR
4h 36m1 stop
$245American Airlines
Find Deal
Wed, Feb 11 - Wed, Feb 18
American Airlines Logo
6:23 am - 1:03 pmMYR-EYW
6h 40m2 stops
American Airlines Logo
6:43 pm - 11:57 pmEYW-MYR
5h 14m1 stop
$249American Airlines
Find Deal
Sun, Jan 18 - Tue, Feb 10

Spirit Airlines flights from Myrtle Beach to Key West

Our best Spirit Airlines deals on Myrtle Beach to Key West flight tickets
Spirit Airlines
Jan 22
MYR8:15 pmMyrtle Beach Intl
17h 15m
1 stop
EYW1:30 pmKey West
Jan 25
EYW12:15 pmKey West
7h 05m
1 stop
MYR7:20 pmMyrtle Beach Intl
$227
Find similar
Spirit Airlines
Jan 4
MYR9:54 amMyrtle Beach Intl
27h 36m
1 stop
EYW1:30 pmKey West
Jan 6
EYW12:20 pmKey West
5h 48m
1 stop
MYR6:08 pmMyrtle Beach Intl
$231
Find similar
Spirit Airlines
Feb 1
MYR8:15 pmMyrtle Beach Intl
17h 15m
1 stop
EYW1:30 pmKey West
Feb 5
EYW12:15 pmKey West
7h 05m
1 stop
MYR7:20 pmMyrtle Beach Intl
$232
Find similar

American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets
American Airlines
Feb 15
MYR3:18 pmMyrtle Beach Intl
7h 25m
1 stop
EYW10:43 pmKey West
Feb 19
EYW4:40 pmKey West
5h 54m
1 stop
MYR10:34 pmMyrtle Beach Intl
$239
Find similar
American Airlines
Jan 18
MYR12:05 pmMyrtle Beach Intl
5h 56m
1 stop
EYW6:01 pmKey West
Feb 10
EYW6:43 pmKey West
5h 14m
1 stop
MYR11:57 pmMyrtle Beach Intl
$244
Find similar
American Airlines
Feb 11
MYR5:29 pmMyrtle Beach Intl
4h 18m
1 stop
EYW9:47 pmKey West
Feb 18
EYW6:20 pmKey West
4h 36m
1 stop
MYR10:56 pmMyrtle Beach Intl
$245
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/22

8:15 pm-1:30 pm

1 stop17h 15m

Key West

Sun 1/25

12:15 pm-7:20 pm

1 stop7h 05m

$227

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 1/4

9:54 am-1:30 pm

1 stop27h 36m

Key West

Tue 1/6

12:20 pm-6:08 pm

1 stop5h 48m

$231

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 2/1

8:15 pm-1:30 pm

1 stop17h 15m

Key West

Thu 2/5

12:15 pm-7:20 pm

1 stop7h 05m

$232

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/29

8:15 pm-1:30 pm

1 stop17h 15m

Key West

Sun 2/1

12:15 pm-7:20 pm

1 stop7h 05m

$233

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 12/23

9:54 am-1:30 pm

1 stop27h 36m

Key West

Sun 12/28

12:20 pm-6:08 pm

1 stop5h 48m

$234

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 1/23

6:09 pm-10:09 am

1 stop16h 00m

Key West

Mon 1/26

2:25 pm-7:20 pm

1 stop4h 55m

$236

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 2/15

3:18 pm-10:43 pm

1 stop7h 25m

Key West

Thu 2/19

4:40 pm-10:34 pm

1 stop5h 54m

$239

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 1/18

12:05 pm-6:01 pm

1 stop5h 56m

Key West

Tue 2/10

6:43 pm-11:57 pm

1 stop5h 14m

$244

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 2/11

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Wed 2/18

6:20 pm-10:56 pm

1 stop4h 36m

$245

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 1/18

6:23 am-1:03 pm

2 stops6h 40m

Key West

Tue 2/10

6:43 pm-11:57 pm

1 stop5h 14m

$249

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you are unable to visit Key West during the month of September, then departing from Myrtle Beach during the month August is also very affordable. Most momondo users find prices during this month for around $367.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Myrtle Beach is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $398. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Key West for around $603.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is in the afternoon. momondo users have found flights departing from Myrtle Beach to Key West in the afternoon for as low as $445. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the morning, with an average ticket price of $488. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $449 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Myrtle Beach for as low as $291 on momondo.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 61% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

4h 06m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 4h 06m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 18m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
7,998 reviews
Search Delta flights
American AirlinesPriceFrom $279Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 12/26
Fri 1/2
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States