What is the cheapest airline that flies from Myrtle Beach Intl to Key West?

Breeze Airways is the most popular carrier operating from Myrtle Beach Intl to Key West

What airlines fly to Key West?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Key West from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Key West. Keep in mind that there are 3 different airlines that fly to Key West on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

As of November 2026, there are 2 operators available to choose from for flights from Myrtle Beach Intl Airport to Key West Airport.

How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

What documentation or ID do you need to fly to Key West Airport?

The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$228 Cheap Flights from Myrtle Beach to Key West in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Key West

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:25 pm - 3:08 pmMYR Myrtle Beach Intl-EYW Key West

20h 43m1 stop Tampa

6:20 pm - 8:45 amEYW Key West-MYR Myrtle Beach Intl

14h 25m1 stop Orlando Sanford Intl

$261Multiple Airlines

Sun, Dec 13 - Thu, Dec 17

5:58 pm - 2:31 pmMYR Myrtle Beach Intl-EYW Key West

20h 33m1 stop Tampa

6:20 pm - 8:45 amEYW Key West-MYR Myrtle Beach Intl

14h 25m1 stop Orlando Sanford Intl

$261Multiple Airlines

Sat, Dec 12 - Thu, Dec 17

5:58 pm - 2:31 pmMYR Myrtle Beach Intl-EYW Key West

20h 33m1 stop Tampa

3:10 pm - 8:03 amEYW Key West-MYR Myrtle Beach Intl

16h 53m2 stops Tampa St. Petersburg Fort Lauderdale

$277Multiple Airlines

Sat, Dec 12 - Thu, Dec 17

6:25 pm - 3:08 pmMYR Myrtle Beach Intl-EYW Key West

20h 43m1 stop Tampa

3:10 pm - 8:03 amEYW Key West-MYR Myrtle Beach Intl

16h 53m2 stops Tampa St. Petersburg Fort Lauderdale

$277Multiple Airlines

Sun, Dec 13 - Thu, Dec 17

6:30 pm - 10:36 pmMYR Myrtle Beach Intl-EYW Key West

4h 06m1 stop Charlotte Douglas

8:05 am - 1:27 pmEYW Key West-MYR Myrtle Beach Intl

5h 22m1 stop Charlotte Douglas

$349American Airlines

Thu, May 6 - Tue, May 11

4:14 pm - 10:36 pmMYR Myrtle Beach Intl-EYW Key West

6h 22m1 stop Charlotte Douglas

1:36 pm - 10:36 pmEYW Key West-MYR Myrtle Beach Intl

9h 00m2 stops Miami Charlotte Douglas

$418American Airlines

Thu, May 6 - Tue, May 11

6:30 pm - 10:36 pmMYR Myrtle Beach Intl-EYW Key West

4h 06m1 stop Charlotte Douglas

4:20 pm - 10:36 pmEYW Key West-MYR Myrtle Beach Intl

6h 16m1 stop Charlotte Douglas

$563American Airlines

Thu, Apr 15 - Sun, Apr 18

1:05 pm - 5:11 pmMYR Myrtle Beach Intl-EYW Key West

4h 06m1 stop Atlanta Hartsfield-Jackson

6:00 pm - 11:35 pmEYW Key West-MYR Myrtle Beach Intl

5h 35m1 stop Atlanta Hartsfield-Jackson

$577Delta

Sun, Apr 25 - Wed, Apr 28

10:52 am - 5:10 pmMYR Myrtle Beach Intl-EYW Key West

6h 18m1 stop Atlanta Hartsfield-Jackson

2:07 pm - 10:54 pmEYW Key West-MYR Myrtle Beach Intl

8h 47m1 stop Atlanta Hartsfield-Jackson

$603Delta

Wed, Nov 25 - Mon, Nov 30

2:18 pm - 8:00 pmMYR Myrtle Beach Intl-EYW Key West

5h 42m1 stop Atlanta Hartsfield-Jackson

6:08 pm - 10:54 pmEYW Key West-MYR Myrtle Beach Intl

4h 46m1 stop Atlanta Hartsfield-Jackson

$737Delta

Wed, Nov 25 - Mon, Nov 30

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Delta flights from Myrtle Beach to Key West

Our best Delta deals on Myrtle Beach to Key West flight tickets

Delta

Apr 25

MYR1:05 pmMyrtle Beach Intl

4h 06m

1 stop

EYW5:11 pmKey West

Apr 28

EYW6:00 pmKey West

5h 35m

1 stop

MYR11:35 pmMyrtle Beach Intl

$577

Delta

Nov 25

MYR10:52 amMyrtle Beach Intl

6h 18m

1 stop

EYW5:10 pmKey West

Nov 30

EYW2:07 pmKey West

8h 47m

1 stop

MYR10:54 pmMyrtle Beach Intl

$603

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets

Breeze Airways

Dec 13

MYR2:46 pmMyrtle Beach Intl

19h 33m

1 stop

EYW10:19 amKey West

Dec 18

EYW12:59 pmKey West

26h 00m

1 stop

MYR2:59 pmMyrtle Beach Intl

$325

Breeze Airways

Dec 13

MYR2:46 pmMyrtle Beach Intl

19h 33m

1 stop

EYW10:19 amKey West

Dec 18

EYW12:59 pmKey West

20h 29m

2 stops

MYR9:28 amMyrtle Beach Intl

$329

Breeze Airways

Dec 30

MYR2:57 pmMyrtle Beach Intl

20h 24m

2 stops

EYW11:21 amKey West

Jan 6

EYW12:19 pmKey West

23h 55m

1 stop

MYR12:14 pmMyrtle Beach Intl

$330

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sun 12/13

6:25 pm-3:08 pm

1 stop20h 43m

Key West

Thu 12/17

6:20 pm-8:45 am

1 stop14h 25m

$261

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sat 12/12

5:58 pm-2:31 pm

1 stop20h 33m

Key West

Thu 12/17

6:20 pm-8:45 am

1 stop14h 25m

$261

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sat 12/12

5:58 pm-2:31 pm

1 stop20h 33m

Key West

Thu 12/17

3:10 pm-8:03 am

2 stops16h 53m

$277

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sun 12/13

6:25 pm-3:08 pm

1 stop20h 43m

Key West

Thu 12/17

3:10 pm-8:03 am

2 stops16h 53m

$277

Quickest round-trip

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Thu 5/6

6:30 pm-10:36 pm

1 stop4h 06m

Key West

Tue 5/11

8:05 am-1:27 pm

1 stop5h 22m

$349

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Thu 5/6

4:14 pm-10:36 pm

1 stop6h 22m

Key West

Tue 5/11

1:36 pm-10:36 pm

2 stops9h 00m

$418

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Thu 4/15

6:30 pm-10:36 pm

1 stop4h 06m

Key West

Sun 4/18

4:20 pm-10:36 pm

1 stop6h 16m

$563

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Sun 4/25

1:05 pm-5:11 pm

1 stop4h 06m

Key West

Wed 4/28

6:00 pm-11:35 pm

1 stop5h 35m

$577

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Wed 11/25

10:52 am-5:10 pm

1 stop6h 18m

Key West

Mon 11/30

2:07 pm-10:54 pm

1 stop8h 47m

$603

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Wed 11/25

2:18 pm-8:00 pm

1 stop5h 42m

Key West

Mon 11/30

6:08 pm-10:54 pm

1 stop4h 46m

$737

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

Prices are currently low for flights on this route.

Typical prices usually range from $338 to $693.
The lowest price recently found on this route was $261.

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $335. If you are unable to visit Key West during the month of January, then departing from Myrtle Beach during the month September is also very affordable. Most momondo users find prices during this month for around $377.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Best Price Found	$228
Fastest flight time	17h 00m
Direct flights	None

The best one-way flight to Key West from Myrtle Beach in the past 72 hours is $228. The best round-trip flight deal from Myrtle Beach to Key West found on momondo in the last 72 hours is $261.

The fastest flight from Myrtle Beach to Key West takes 17h 00m

There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.

Search flight deals

Frequently asked questions about flying from Myrtle Beach to Key West

How far is Myrtle Beach Intl to Key West by plane?
A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 17h 00m by plane in normal conditions.
When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?
Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?
As of November 2026, there are 2 operators available to choose from for flights from Myrtle Beach Intl Airport to Key West Airport.
How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.
What documentation or ID do you need to fly to Key West Airport?
The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Myrtle Beach to Key West?
Based on momondo bookings for flights between Myrtle Beach and Key West, the leading airline is American Airlines, making up 69% of the total bookings. Other popular airlines include Delta with 31%.

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $302	Free Cancellation	Rating 7.0 12,228 reviews		Search American Airlines flights
Delta	PriceFrom $305	Free Cancellation	Rating 7.8 8,698 reviews		Search Delta flights

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Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Myrtle Beach to Key West from $228

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 2/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from Myrtle Beach to Key West

Our best Delta deals on Myrtle Beach to Key West flight tickets

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets

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How to get the cheapest flight ticket from Myrtle Beach to Key West

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

What is the cheapest month to fly to Key West?

What is the cheapest airline that flies from Myrtle Beach Intl to Key West?

What airlines fly to Key West?

When to book flights from Myrtle Beach to Key West

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Myrtle Beach to Key West

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo

Traveling to a place near Key West?

Why use momondo?

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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List of cabin classes available on flights landing in Key West. Availability may vary depending on flight origin and airline.

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