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Cheap flights from Myrtle Beach to Key West from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 8/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:21 pm - 7:13 pm
MYR
-
EYW
26h 52m
1 stop
Multiple Airlines Logo
10:04 am - 7:20 pm
EYW
-
MYR
33h 16m
2 stops
$280Multiple Airlines
Sat, Sep 5 - Sat, Sep 19
Breeze Airways Logo
3:53 pm - 11:27 am
MYR
-
EYW
19h 34m
1 stop
Breeze Airways Logo
1:14 pm - 11:39 am
EYW
-
MYR
22h 25m
1 stop
$292Breeze Airways
Thu, Jun 11 - Tue, Jun 16
Multiple Airlines Logo
4:21 pm - 7:13 pm
MYR
-
EYW
26h 52m
1 stop
Multiple Airlines Logo
9:53 am - 7:20 pm
EYW
-
MYR
33h 27m
2 stops
$293Multiple Airlines
Sat, Sep 5 - Sat, Sep 19
Allegiant Air Logo
8:11 pm - 8:26 pm
MYR
-
EYW
24h 15m
1 stop
Allegiant Air Logo
2:44 pm - 10:52 am
EYW
-
MYR
20h 08m
2 stops
$298Allegiant Air
Sat, Jun 27 - Sat, Jul 4
American Airlines Logo
12:10 pm - 5:55 pm
MYR
-
EYW
5h 45m
1 stop
American Airlines Logo
6:27 pm - 10:53 pm
EYW
-
MYR
4h 26m
1 stop
$303American Airlines
Sat, Sep 12 - Sat, Sep 19
American Airlines Logo
2:45 pm - 9:47 pm
MYR
-
EYW
7h 02m
1 stop
American Airlines Logo
4:53 pm - 11:55 pm
EYW
-
MYR
7h 02m
1 stop
$306American Airlines
Mon, Nov 2 - Sat, Nov 7
Delta Logo
1:54 pm - 7:53 pm
MYR
-
EYW
5h 59m
1 stop
Delta Logo
7:50 am - 1:00 pm
EYW
-
MYR
5h 10m
1 stop
$309Delta
Fri, Jul 3 - Thu, Jul 9
Multiple Airlines Logo
4:51 pm - 1:54 pm
MYR
-
EYW
21h 03m
2 stops
Multiple Airlines Logo
7:53 pm - 2:06 pm
EYW
-
MYR
18h 13m
1 stop
$312Multiple Airlines
Fri, Jul 3 - Thu, Jul 9
Delta Logo
1:54 pm - 7:53 pm
MYR
-
EYW
5h 59m
1 stop
Delta Logo
2:24 pm - 7:07 pm
EYW
-
MYR
4h 43m
1 stop
$321Delta
Fri, Jul 3 - Thu, Jul 9
Multiple Airlines Logo
4:21 pm - 7:13 pm
MYR
-
EYW
26h 52m
1 stop
Multiple Airlines Logo
9:53 am - 12:14 pm
EYW
-
MYR
26h 21m
1 stop
$322Multiple Airlines
Sat, Sep 5 - Sat, Sep 19

American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets
American Airlines
Sep 12
MYR12:10 pmMyrtle Beach Intl
5h 45m
1 stop
EYW5:55 pmKey West
Sep 19
EYW6:27 pmKey West
4h 26m
1 stop
MYR10:53 pmMyrtle Beach Intl
$303
American Airlines
Nov 2
MYR2:45 pmMyrtle Beach Intl
7h 02m
1 stop
EYW9:47 pmKey West
Nov 7
EYW4:53 pmKey West
7h 02m
1 stop
MYR11:55 pmMyrtle Beach Intl
$306
American Airlines
Sep 5
MYR6:43 amMyrtle Beach Intl
5h 44m
1 stop
EYW12:27 pmKey West
Sep 19
EYW6:27 pmKey West
4h 26m
1 stop
MYR10:53 pmMyrtle Beach Intl
$341

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Jun 11
MYR3:53 pmMyrtle Beach Intl
19h 34m
1 stop
EYW11:27 amKey West
Jun 16
EYW1:14 pmKey West
22h 25m
1 stop
MYR11:39 amMyrtle Beach Intl
$292
Breeze Airways
Jun 4
MYR3:53 pmMyrtle Beach Intl
19h 34m
1 stop
EYW11:27 amKey West
Jun 7
EYW12:05 pmKey West
21h 00m
1 stop
MYR9:05 amMyrtle Beach Intl
$353
Breeze Airways
Sep 12
MYR5:58 pmMyrtle Beach Intl
17h 23m
1 stop
EYW11:21 amKey West
Sep 19
EYW10:04 amKey West
31h 41m
2 stops
MYR5:45 pmMyrtle Beach Intl
$374

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 30, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 9/5

4:21 pm-7:13 pm

1 stop26h 52m

Key West

Sat 9/19

10:04 am-7:20 pm

2 stops33h 16m

$280

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 6/11

3:53 pm-11:27 am

1 stop19h 34m

Key West

Tue 6/16

1:14 pm-11:39 am

1 stop22h 25m

$292

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 9/5

4:21 pm-7:13 pm

1 stop26h 52m

Key West

Sat 9/19

9:53 am-7:20 pm

2 stops33h 27m

$293

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 6/27

8:11 pm-8:26 pm

1 stop24h 15m

Key West

Sat 7/4

2:44 pm-10:52 am

2 stops20h 08m

$298
Quickest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 9/12

12:10 pm-5:55 pm

1 stop5h 45m

Key West

Sat 9/19

6:27 pm-10:53 pm

1 stop4h 26m

$303

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 11/2

2:45 pm-9:47 pm

1 stop7h 02m

Key West

Sat 11/7

4:53 pm-11:55 pm

1 stop7h 02m

$306

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 7/3

1:54 pm-7:53 pm

1 stop5h 59m

Key West

Thu 7/9

7:50 am-1:00 pm

1 stop5h 10m

$309

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 7/3

4:51 pm-1:54 pm

2 stops21h 03m

Key West

Thu 7/9

7:53 pm-2:06 pm

1 stop18h 13m

$312

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 7/3

1:54 pm-7:53 pm

1 stop5h 59m

Key West

Thu 7/9

2:24 pm-7:07 pm

1 stop4h 43m

$321

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 9/5

4:21 pm-7:13 pm

1 stop26h 52m

Key West

Sat 9/19

9:53 am-12:14 pm

1 stop26h 21m

$322

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $335. If you are unable to visit Key West during the month of January, then departing from Myrtle Beach during the month June is also very affordable. Most momondo users find prices during this month for around $368.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 14% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

4h 50m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 4h 50m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Key West

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 50m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,416 reviews
Search Delta flights
American AirlinesPriceFrom $263Free CancellationRating
7.1
11,640 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Key West trip

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