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Cheap flights from Myrtle Beach to Key West from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 5/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:30 am - 1:07 pm
MYR
-
EYW
30h 37m
2 stops
Multiple Airlines Logo
10:39 am - 12:19 pm
EYW
-
MYR
25h 40m
1 stop
$274Multiple Airlines
Sat, May 9 - Wed, May 13
Breeze Airways Logo
2:42 pm - 11:25 am
MYR
-
EYW
20h 43m
1 stop
Breeze Airways Logo
11:46 am - 12:19 pm
EYW
-
MYR
24h 33m
1 stop
$287Breeze Airways
Sat, May 9 - Wed, May 13
Multiple Airlines Logo
2:42 pm - 1:07 pm
MYR
-
EYW
22h 25m
1 stop
Multiple Airlines Logo
10:39 am - 12:19 pm
EYW
-
MYR
25h 40m
1 stop
$290Multiple Airlines
Sat, May 9 - Wed, May 13
American Airlines Logo
6:30 pm - 10:36 pm
MYR
-
EYW
4h 06m
1 stop
American Airlines Logo
8:05 am - 1:27 pm
EYW
-
MYR
5h 22m
1 stop
$291American Airlines
Wed, May 13 - Wed, May 20
Multiple Airlines Logo
2:42 pm - 11:25 am
MYR
-
EYW
20h 43m
1 stop
Multiple Airlines Logo
11:46 am - 8:36 pm
EYW
-
MYR
32h 50m
2 stops
$292Multiple Airlines
Sat, May 9 - Wed, May 13
American Airlines Logo
1:57 pm - 10:58 pm
MYR
-
EYW
9h 01m
2 stops
American Airlines Logo
8:05 am - 1:27 pm
EYW
-
MYR
5h 22m
1 stop
$296American Airlines
Wed, May 13 - Wed, May 20
Breeze Airways Logo
2:42 pm - 11:25 am
MYR
-
EYW
20h 43m
1 stop
Breeze Airways Logo
11:46 am - 12:19 pm
EYW
-
MYR
24h 33m
1 stop
$298Breeze Airways
Sat, May 9 - Wed, May 13
American Airlines Logo
5:00 am - 1:08 pm
MYR
-
EYW
8h 08m
2 stops
American Airlines Logo
11:24 am - 10:24 pm
EYW
-
MYR
11h 00m
2 stops
$301American Airlines
Sat, May 9 - Wed, May 13
Multiple Airlines Logo
3:58 pm - 11:02 am
MYR
-
EYW
19h 04m
1 stop
Multiple Airlines Logo
12:05 pm - 9:05 am
EYW
-
MYR
21h 00m
1 stop
$305Multiple Airlines
Thu, May 21 - Thu, May 28
American Airlines Logo
4:09 pm - 10:36 pm
MYR
-
EYW
6h 27m
1 stop
American Airlines Logo
8:05 am - 1:27 pm
EYW
-
MYR
5h 22m
1 stop
$310American Airlines
Wed, May 13 - Wed, May 20

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Delta flights from Myrtle Beach to Key West

Our best Delta deals on Myrtle Beach to Key West flight tickets
Delta
May 2
MYR10:26 amMyrtle Beach Intl
6h 57m
1 stop
EYW5:23 pmKey West
May 6
EYW6:23 pmKey West
5h 51m
1 stop
MYR12:14 amMyrtle Beach Intl
$379
Delta
Jun 19
MYR1:51 pmMyrtle Beach Intl
6h 02m
1 stop
EYW7:53 pmKey West
Jun 24
EYW6:24 pmKey West
5h 35m
1 stop
MYR11:59 pmMyrtle Beach Intl
$391
Delta
May 29
MYR11:43 amMyrtle Beach Intl
5h 40m
1 stop
EYW5:23 pmKey West
Jun 3
EYW6:19 pmKey West
5h 39m
1 stop
MYR11:58 pmMyrtle Beach Intl
$404

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
May 9
MYR2:42 pmMyrtle Beach Intl
20h 43m
1 stop
EYW11:25 amKey West
May 13
EYW11:46 amKey West
24h 33m
1 stop
MYR12:19 pmMyrtle Beach Intl
$287
Breeze Airways
May 9
MYR2:42 pmMyrtle Beach Intl
20h 43m
1 stop
EYW11:25 amKey West
May 13
EYW11:46 amKey West
24h 33m
1 stop
MYR12:19 pmMyrtle Beach Intl
$298
Breeze Airways
Jul 5
MYR3:53 pmMyrtle Beach Intl
19h 34m
1 stop
EYW11:27 amKey West
Jul 9
EYW7:56 pmKey West
13h 54m
2 stops
MYR9:50 amMyrtle Beach Intl
$325

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 5/9

6:30 am-1:07 pm

2 stops30h 37m

Key West

Wed 5/13

10:39 am-12:19 pm

1 stop25h 40m

$274

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 5/9

2:42 pm-11:25 am

1 stop20h 43m

Key West

Wed 5/13

11:46 am-12:19 pm

1 stop24h 33m

$287

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 5/9

2:42 pm-1:07 pm

1 stop22h 25m

Key West

Wed 5/13

10:39 am-12:19 pm

1 stop25h 40m

$290
Quickest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 5/13

6:30 pm-10:36 pm

1 stop4h 06m

Key West

Wed 5/20

8:05 am-1:27 pm

1 stop5h 22m

$291

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 5/9

2:42 pm-11:25 am

1 stop20h 43m

Key West

Wed 5/13

11:46 am-8:36 pm

2 stops32h 50m

$292

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 5/13

1:57 pm-10:58 pm

2 stops9h 01m

Key West

Wed 5/20

8:05 am-1:27 pm

1 stop5h 22m

$296

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 5/9

2:42 pm-11:25 am

1 stop20h 43m

Key West

Wed 5/13

11:46 am-12:19 pm

1 stop24h 33m

$298

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 5/9

5:00 am-1:08 pm

2 stops8h 08m

Key West

Wed 5/13

11:24 am-10:24 pm

2 stops11h 00m

$301

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 5/21

3:58 pm-11:02 am

1 stop19h 04m

Key West

Thu 5/28

12:05 pm-9:05 am

1 stop21h 00m

$305

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 5/13

4:09 pm-10:36 pm

1 stop6h 27m

Key West

Wed 5/20

8:05 am-1:27 pm

1 stop5h 22m

$310

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $335. If you are unable to visit Key West during the month of January, then departing from Myrtle Beach during the month June is also very affordable. Most momondo users find prices during this month for around $353.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 14% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

4h 46m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 4h 46m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Key West

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 46m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,430 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,647 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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