Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Myrtle Beach to Key West from $128

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 10/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Myrtle Beach to Key West

Cheap round-trip flights

American Airlines Logo
9:09 am - 3:18 pmMYR-EYW
6h 09m1 stop
American Airlines Logo
8:10 am - 2:10 pmEYW-MYR
6h 00m1 stop
$225American Airlines
Find Deal
Tue, Jan 13 - Sat, Jan 17
American Airlines Logo
2:27 pm - 11:59 pmMYR-EYW
9h 32m2 stops
American Airlines Logo
8:10 am - 2:10 pmEYW-MYR
6h 00m1 stop
$230American Airlines
Find Deal
Tue, Jan 13 - Sat, Jan 17
American Airlines Logo
2:27 pm - 11:59 pmMYR-EYW
9h 32m2 stops
American Airlines Logo
6:31 am - 2:10 pmEYW-MYR
7h 39m2 stops
$235American Airlines
Find Deal
Tue, Jan 13 - Sat, Jan 17
American Airlines Logo
11:10 am - 6:35 pmMYR-EYW
7h 25m1 stop
American Airlines Logo
8:10 am - 12:15 pmEYW-MYR
4h 05m1 stop
$249American Airlines
Find Deal
Fri, Feb 6 - Mon, Feb 9
American Airlines Logo
3:29 pm - 9:46 pmMYR-EYW
6h 17m1 stop
American Airlines Logo
11:35 am - 10:05 pmEYW-MYR
10h 30m2 stops
$254American Airlines
Find Deal
Mon, Dec 8 - Sat, Dec 13
Logo
8:30 pm - 8:15 amMYR-EYW
11h 45m1 stop
Logo
8:50 pm - 8:44 amEYW-MYR
11h 54m1 stop
$288
Find Deal
Thu, Dec 4 - Sun, Dec 7
Breeze Airways Logo
10:45 am - 8:15 amMYR-EYW
45h 30m2 stops
Breeze Airways Logo
10:47 am - 8:49 amEYW-MYR
22h 02m1 stop
$301Breeze Airways
Find Deal
Tue, Sep 30 - Sat, Oct 4
Logo
1:53 pm - 5:46 pmMYR-EYW
27h 53m1 stop
Logo
8:55 am - 2:54 pmEYW-MYR
29h 59m2 stops
$304
Find Deal
Sun, Oct 5 - Thu, Oct 9
Delta Logo
2:35 pm - 8:06 pmMYR-EYW
5h 31m1 stop
Delta Logo
7:40 am - 1:56 pmEYW-MYR
6h 16m1 stop
$314Delta
Find Deal
Fri, Nov 7 - Sun, Nov 9
Delta Logo
6:00 am - 10:55 amMYR-EYW
4h 55m1 stop
Delta Logo
6:10 pm - 11:49 pmEYW-MYR
5h 39m1 stop
$454Delta
Find Deal
Tue, Sep 30 - Sat, Oct 4

American Airlines flights from Myrtle Beach to Key West

Our best American Airlines deals on Myrtle Beach to Key West flight tickets
American Airlines
Jan 13
MYR9:09 amMyrtle Beach Intl
6h 09m
1 stop
EYW3:18 pmKey West
Jan 17
EYW8:10 amKey West
6h 00m
1 stop
MYR2:10 pmMyrtle Beach Intl
$225
Find similar
American Airlines
Jan 13
MYR2:27 pmMyrtle Beach Intl
9h 32m
2 stops
EYW11:59 pmKey West
Jan 17
EYW8:10 amKey West
6h 00m
1 stop
MYR2:10 pmMyrtle Beach Intl
$230
Find similar
American Airlines
Jan 13
MYR2:27 pmMyrtle Beach Intl
9h 32m
2 stops
EYW11:59 pmKey West
Jan 17
EYW6:31 amKey West
7h 39m
2 stops
MYR2:10 pmMyrtle Beach Intl
$235
Find similar

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Sep 30
MYR10:45 amMyrtle Beach Intl
45h 30m
2 stops
EYW8:15 amKey West
Oct 4
EYW10:47 amKey West
22h 02m
1 stop
MYR8:49 amMyrtle Beach Intl
$301
Find similar
Breeze Airways
Sep 28
MYR9:36 amMyrtle Beach Intl
22h 31m
3 stops
EYW8:07 amKey West
Oct 2
EYW8:55 amKey West
33h 16m
2 stops
MYR6:11 pmMyrtle Beach Intl
$822
Find similar
Breeze Airways
Sep 28
MYR9:36 amMyrtle Beach Intl
22h 31m
3 stops
EYW8:07 amKey West
Oct 2
EYW8:55 amKey West
24h 21m
3 stops
MYR9:16 amMyrtle Beach Intl
$885
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 1/13

9:09 am-3:18 pm

1 stop6h 09m

Key West

Sat 1/17

8:10 am-2:10 pm

1 stop6h 00m

$225

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 1/13

2:27 pm-11:59 pm

2 stops9h 32m

Key West

Sat 1/17

8:10 am-2:10 pm

1 stop6h 00m

$230

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 1/13

2:27 pm-11:59 pm

2 stops9h 32m

Key West

Sat 1/17

6:31 am-2:10 pm

2 stops7h 39m

$235

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 2/6

11:10 am-6:35 pm

1 stop7h 25m

Key West

Mon 2/9

8:10 am-12:15 pm

1 stop4h 05m

$249

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 12/8

3:29 pm-9:46 pm

1 stop6h 17m

Key West

Sat 12/13

11:35 am-10:05 pm

2 stops10h 30m

$254

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 12/4

8:30 pm-8:15 am

1 stop11h 45m

Key West

Sun 12/7

8:50 pm-8:44 am

1 stop11h 54m

$288

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 9/30

10:45 am-8:15 am

2 stops45h 30m

Key West

Sat 10/4

10:47 am-8:49 am

1 stop22h 02m

$301

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 10/5

1:53 pm-5:46 pm

1 stop27h 53m

Key West

Thu 10/9

8:55 am-2:54 pm

2 stops29h 59m

$304

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 11/7

2:35 pm-8:06 pm

1 stop5h 31m

Key West

Sun 11/9

7:40 am-1:56 pm

1 stop6h 16m

$314

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 9/30

6:00 am-10:55 am

1 stop4h 55m

Key West

Sat 10/4

6:10 pm-11:49 pm

1 stop5h 39m

$454

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Key West?

What is the cheapest month to fly to Key West?

In general, November is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $362. If you are unable to visit Key West during the month of November, then departing from Myrtle Beach during the month September is also very affordable. Most momondo users find prices during this month for around $366.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Myrtle Beach is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $398. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Key West for around $603.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is in the afternoon. momondo users have found flights departing from Myrtle Beach to Key West in the afternoon for as low as $445. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the morning, with an average ticket price of $488. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $447 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Myrtle Beach for as low as $291 on momondo.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 23% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Direct flights

None
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 08m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
7,954 reviews
Search Delta flights
American AirlinesPriceFrom $283Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 10/15
Wed 10/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States