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Cheap flights from Myrtle Beach to Key West from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Key West departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Myrtle Beach to Key West

Cheap round-trip flights

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American Airlines Logo
5:29 pm - 9:47 pm
MYR
-
EYW
4h 18m1 stop
American Airlines Logo
4:04 pm - 8:54 pm
EYW
-
MYR
4h 50m1 stop
$199American Airlines
Thu, Jan 8 - Mon, Jan 12
American Airlines Logo
1:53 pm - 11:56 pm
MYR
-
EYW
10h 03m2 stops
American Airlines Logo
4:04 pm - 11:15 pm
EYW
-
MYR
7h 11m1 stop
$204American Airlines
Thu, Jan 8 - Mon, Jan 12
American Airlines Logo
1:53 pm - 11:56 pm
MYR
-
EYW
10h 03m2 stops
American Airlines Logo
4:37 pm - 11:57 pm
EYW
-
MYR
7h 20m2 stops
$209American Airlines
Fri, Jan 23 - Tue, Jan 27
Spirit Airlines Logo
8:15 pm - 1:30 pm
MYR
-
EYW
17h 15m1 stop
Spirit Airlines Logo
2:25 pm - 7:20 pm
EYW
-
MYR
4h 55m1 stop
$227Spirit Airlines
Thu, Feb 5 - Mon, Feb 9
American Airlines Logo
3:18 pm - 10:43 pm
MYR
-
EYW
7h 25m1 stop
American Airlines Logo
6:20 pm - 10:56 pm
EYW
-
MYR
4h 36m1 stop
$239American Airlines
Sat, Feb 14 - Wed, Feb 18
American Airlines Logo
1:53 pm - 11:56 pm
MYR
-
EYW
10h 03m2 stops
American Airlines Logo
6:43 pm - 11:15 pm
EYW
-
MYR
4h 32m1 stop
$244American Airlines
Thu, Feb 5 - Mon, Feb 9
American Airlines Logo
10:18 am - 7:10 pm
MYR
-
EYW
8h 52m2 stops
American Airlines Logo
6:06 am - 1:23 pm
EYW
-
MYR
7h 17m2 stops
$249American Airlines
Thu, Jan 8 - Mon, Jan 12
Breeze Airways Logo
5:53 pm - 9:09 am
MYR
-
EYW
15h 16m1 stop
Breeze Airways Logo
10:49 am - 11:43 am
EYW
-
MYR
24h 54m1 stop
$257Breeze Airways
Sun, Feb 1 - Wed, Feb 4
Spirit Airlines Logo
8:15 pm - 1:30 pm
MYR
-
EYW
17h 15m1 stop
Spirit Airlines Logo
12:51 pm - 7:20 pm
EYW
-
MYR
6h 29m1 stop
$262Spirit Airlines
Thu, Jan 29 - Sun, Feb 1
Multiple Airlines Logo
9:54 am - 1:30 pm
MYR
-
EYW
27h 36m1 stop
Multiple Airlines Logo
8:55 am - 6:37 pm
EYW
-
MYR
9h 42m1 stop
$265Multiple Airlines
Thu, Dec 25 - Sun, Dec 28

Breeze Airways flights from Myrtle Beach to Key West

Our best Breeze Airways deals on Myrtle Beach to Key West flight tickets
Breeze Airways
Feb 1
MYR5:53 pmMyrtle Beach Intl
15h 16m
1 stop
EYW9:09 amKey West
Feb 4
EYW10:49 amKey West
24h 54m
1 stop
MYR11:43 amMyrtle Beach Intl
$257
Find similar
Breeze Airways
Feb 1
MYR5:53 pmMyrtle Beach Intl
15h 16m
1 stop
EYW9:09 amKey West
Feb 4
EYW10:49 amKey West
23h 16m
2 stops
MYR10:05 amMyrtle Beach Intl
$284
Find similar
Breeze Airways
Dec 18
MYR2:59 pmMyrtle Beach Intl
18h 18m
1 stop
EYW9:17 amKey West
Dec 22
EYW11:11 amKey West
30h 40m
2 stops
MYR5:51 pmMyrtle Beach Intl
$287
Find similar

Delta flights from Myrtle Beach to Key West

Our best Delta deals on Myrtle Beach to Key West flight tickets
Delta
Dec 13
MYR4:00 pmMyrtle Beach Intl
4h 06m
1 stop
EYW8:06 pmKey West
Dec 17
EYW7:40 amKey West
6h 15m
1 stop
MYR1:55 pmMyrtle Beach Intl
$295
Find similar
Delta
Dec 18
MYR2:39 pmMyrtle Beach Intl
5h 27m
1 stop
EYW8:06 pmKey West
Dec 26
EYW7:25 amKey West
5h 06m
1 stop
MYR12:31 pmMyrtle Beach Intl
$309
Find similar
Delta
Dec 13
MYR4:00 pmMyrtle Beach Intl
4h 06m
1 stop
EYW8:06 pmKey West
Dec 17
EYW7:40 amKey West
6h 15m
1 stop
MYR1:55 pmMyrtle Beach Intl
$339
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/8

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Mon 1/12

4:04 pm-8:54 pm

1 stop4h 50m

$199

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/8

1:53 pm-11:56 pm

2 stops10h 03m

Key West

Mon 1/12

4:04 pm-11:15 pm

1 stop7h 11m

$204

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 1/23

1:53 pm-11:56 pm

2 stops10h 03m

Key West

Tue 1/27

4:37 pm-11:57 pm

2 stops7h 20m

$209

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 2/5

8:15 pm-1:30 pm

1 stop17h 15m

Key West

Mon 2/9

2:25 pm-7:20 pm

1 stop4h 55m

$227

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 2/14

3:18 pm-10:43 pm

1 stop7h 25m

Key West

Wed 2/18

6:20 pm-10:56 pm

1 stop4h 36m

$239

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 2/5

1:53 pm-11:56 pm

2 stops10h 03m

Key West

Mon 2/9

6:43 pm-11:15 pm

1 stop4h 32m

$244

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/8

10:18 am-7:10 pm

2 stops8h 52m

Key West

Mon 1/12

6:06 am-1:23 pm

2 stops7h 17m

$249

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 2/1

5:53 pm-9:09 am

1 stop15h 16m

Key West

Wed 2/4

10:49 am-11:43 am

1 stop24h 54m

$257

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 1/29

8:15 pm-1:30 pm

1 stop17h 15m

Key West

Sun 2/1

12:51 pm-7:20 pm

1 stop6h 29m

$262

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 12/25

9:54 am-1:30 pm

1 stop27h 36m

Key West

Sun 12/28

8:55 am-6:37 pm

1 stop9h 42m

$265

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Myrtle Beach to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Myrtle Beach to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you are unable to visit Key West during the month of September, then departing from Myrtle Beach during the month August is also very affordable. Most momondo users find prices during this month for around $367.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Myrtle Beach is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $398. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Key West for around $603.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is in the afternoon. momondo users have found flights departing from Myrtle Beach to Key West in the afternoon for as low as $445. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the morning, with an average ticket price of $488. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $447 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Myrtle Beach for as low as $291 on momondo.

Can stopping save me money on Myrtle Beach to Key West flights?

You could potentially save up to 61% on your flight if you consider stops on a Myrtle Beach to Key West flight.

When to book flights from Myrtle Beach to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Key West (MYR to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Key West

Fastest flight time

4h 06m

Direct flights

None
The fastest flight from Myrtle Beach to Key West takes 4h 06m
There are no direct flights from Myrtle Beach to Key West. There are no popular flight routes from Myrtle Beach to Key West.
Search flight deals

  • How far is Myrtle Beach Intl to Key West by plane?

    A flight from Myrtle Beach Intl to Key West will travel around 654.6 mi. Typically, this will take 4h 18m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Key West Airport?

    Prices for flights from Myrtle Beach Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Key West Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Key West?

Best airlines flying from Myrtle Beach to Key West

Compare and see reviews for airlines that fly from Myrtle Beach to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,011 reviews
Search Delta flights
American AirlinesPriceFrom $298Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Key West for you.

Can I find flights from Myrtle Beach to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to Key West?

Once all potential Myrtle Beach to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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