What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 69% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Myrtle Beach Intl to Florida Keys?

Southwest, Delta, and Breeze Airways are the most popular carriers operating from Myrtle Beach Intl to Florida Keys

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Florida Keys?

Prices for flights from Myrtle Beach Intl Airport to Florida Keys are updated daily.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Florida Keys?

As of August 2026, there are 3 operators available to choose from for flights from Myrtle Beach Intl Airport to Florida Keys.

How old do you have to be to fly from Myrtle Beach Intl Airport to Florida Keys?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$131 Cheap Flights from Myrtle Beach to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Florida Keys

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:37 am - 7:45 pmMYR Myrtle Beach Intl-MIA Miami

10h 08m1 stop Philadelphia

8:50 pm - 8:52 amMIA Miami-MYR Myrtle Beach Intl

12h 02m1 stop Philadelphia

$201Frontier

Thu, Sep 24 - Wed, Sep 30

9:32 am - 7:45 pmMYR Myrtle Beach Intl-MIA Miami

10h 13m1 stop Philadelphia

8:50 pm - 8:47 amMIA Miami-MYR Myrtle Beach Intl

11h 57m1 stop Philadelphia

$230Frontier

Thu, Oct 15 - Sat, Oct 17

9:36 am - 7:51 pmMYR Myrtle Beach Intl-MIA Miami

10h 15m1 stop Philadelphia

8:56 pm - 8:51 amMIA Miami-MYR Myrtle Beach Intl

11h 55m1 stop Philadelphia

$235Frontier

Sun, Nov 8 - Sat, Nov 14

8:35 pm - 12:42 amMYR Myrtle Beach Intl-MIA Miami

4h 07m1 stop Charlotte Douglas

11:30 am - 3:44 pmMIA Miami-MYR Myrtle Beach Intl

4h 14m1 stop Charlotte Douglas

$309American Airlines

Thu, Dec 10 - Thu, Dec 17

10:17 am - 3:26 pmMYR Myrtle Beach Intl-MIA Miami

5h 09m1 stop Charlotte Douglas

6:00 am - 10:22 amMIA Miami-MYR Myrtle Beach Intl

4h 22m1 stop Charlotte Douglas

$309American Airlines

Wed, Nov 18 - Mon, Nov 23

6:58 pm - 11:31 pmMYR Myrtle Beach Intl-MIA Miami

4h 33m1 stop Atlanta Hartsfield-Jackson

6:04 am - 10:07 amMIA Miami-MYR Myrtle Beach Intl

4h 03m1 stop Atlanta Hartsfield-Jackson

$309Delta

Mon, Oct 19 - Wed, Oct 28

2:16 pm - 7:43 pmMYR Myrtle Beach Intl-MIA Miami

5h 27m1 stop Atlanta Hartsfield-Jackson

6:04 am - 10:07 amMIA Miami-MYR Myrtle Beach Intl

4h 03m1 stop Atlanta Hartsfield-Jackson

$309Delta

Tue, Oct 6 - Wed, Oct 7

10:55 am - 3:40 pmMYR Myrtle Beach Intl-MIA Miami

4h 45m1 stop Atlanta Hartsfield-Jackson

6:00 am - 10:08 amMIA Miami-MYR Myrtle Beach Intl

4h 08m1 stop Atlanta Hartsfield-Jackson

$309Delta

Wed, Feb 24 - Mon, Mar 1

2:30 pm - 10:10 pmMYR Myrtle Beach Intl-MIA Miami

7h 40m2 stops Nashville Intl Orlando

11:50 am - 7:15 pmMIA Miami-MYR Myrtle Beach Intl

7h 25m1 stop Baltimore/Washington

$314Southwest

Thu, Sep 24 - Wed, Sep 30

2:10 pm - 10:10 pmMYR Myrtle Beach Intl-MIA Miami

8h 00m2 stops Baltimore/Washington Orlando

6:45 am - 5:15 pmMIA Miami-MYR Myrtle Beach Intl

10h 30m2 stops Nashville Intl Baltimore/Washington

$319Southwest

Tue, Oct 20 - Sat, Oct 24

Cheap last minute flights

Enter your travel dates to find the best prices.

2:58 pm - 11:27 amMYR Myrtle Beach Intl-EYW Key West

20h 29m1 stop Orlando

10:04 am - 12:14 pmEYW Key West-MYR Myrtle Beach Intl

26h 10m1 stop Tampa

$375Breeze Airways

Thu, Sep 3 - Wed, Sep 9

2:58 pm - 11:27 amMYR Myrtle Beach Intl-EYW Key West

20h 29m1 stop Orlando

12:01 pm - 11:44 amEYW Key West-MYR Myrtle Beach Intl

23h 43m1 stop Tampa

$381Breeze Airways

Thu, Sep 3 - Thu, Sep 10

8:30 pm - 11:27 amMYR Myrtle Beach Intl-EYW Key West

14h 57m2 stops Cleveland Hopkins Intl Orlando

10:04 am - 12:14 pmEYW Key West-MYR Myrtle Beach Intl

26h 10m1 stop Tampa

$395Multiple Airlines

Thu, Sep 3 - Wed, Sep 9

8:30 pm - 11:27 amMYR Myrtle Beach Intl-EYW Key West

14h 57m2 stops Cleveland Hopkins Intl Orlando

12:01 pm - 11:44 amEYW Key West-MYR Myrtle Beach Intl

23h 43m1 stop Tampa

$401Multiple Airlines

Thu, Sep 3 - Thu, Sep 10

8:30 pm - 8:07 pmMYR Myrtle Beach Intl-MIA Miami

23h 37m1 stop Cleveland Hopkins Intl

6:00 am - 7:35 pmMIA Miami-MYR Myrtle Beach Intl

13h 35m2 stops Denver Intl Cleveland Hopkins Intl

$481Frontier

Thu, Sep 3 - Sun, Sep 6

7:30 am - 12:15 pmMYR Myrtle Beach Intl-MIA Miami

4h 45m1 stop Baltimore/Washington

12:40 pm - 8:30 pmMIA Miami-MYR Myrtle Beach Intl

7h 50m1 stop Baltimore/Washington

$581Southwest

Sun, Aug 30 - Sun, Sep 6

2:40 pm - 10:50 pmMYR Myrtle Beach Intl-MIA Miami

8h 10m2 stops Baltimore/Washington Orlando

8:35 am - 8:30 pmMIA Miami-MYR Myrtle Beach Intl

11h 55m2 stops Orlando Baltimore/Washington

$619Southwest

Sun, Aug 30 - Sun, Sep 6

2:30 pm - 8:45 pmMYR Myrtle Beach Intl-MIA Miami

6h 15m1 stop Nashville Intl

7:30 am - 1:50 pmMIA Miami-MYR Myrtle Beach Intl

6h 20m1 stop Baltimore/Washington

$623Southwest

Mon, Aug 31 - Wed, Sep 2

6:40 am - 4:10 pmMYR Myrtle Beach Intl-MIA Miami

9h 30m2 stops Baltimore/Washington Lambert-St Louis

7:30 am - 1:50 pmMIA Miami-MYR Myrtle Beach Intl

6h 20m1 stop Baltimore/Washington

$628Southwest

Mon, Aug 31 - Wed, Sep 2

8:08 am - 1:11 pmMYR Myrtle Beach Intl-MIA Miami

5h 03m1 stop Charlotte Douglas

6:38 pm - 10:38 pmMIA Miami-MYR Myrtle Beach Intl

4h 00m1 stop Charlotte Douglas

$714American Airlines

Thu, Sep 3 - Fri, Sep 4

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American Airlines flights from Myrtle Beach to Florida Keys

Our best American Airlines deals on Myrtle Beach to Florida Keys flight tickets

American Airlines

Nov 5

MYR8:35 pmMyrtle Beach Intl

4h 07m

1 stop

MIA12:42 amMiami

Nov 10

MIA9:35 amMiami

6h 48m

1 stop

MYR4:23 pmMyrtle Beach Intl

$309

American Airlines

Jan 30

MYR12:05 pmMyrtle Beach Intl

5h 56m

1 stop

EYW6:01 pmKey West

Feb 6

EYW6:43 pmKey West

4h 32m

1 stop

MYR11:15 pmMyrtle Beach Intl

$313

American Airlines

Oct 19

MYR2:11 pmMyrtle Beach Intl

6h 40m

1 stop

MIA8:51 pmMiami

Oct 23

MIA5:32 pmMiami

4h 30m

1 stop

MYR10:02 pmMyrtle Beach Intl

$316

Frontier flights from Myrtle Beach to Florida Keys

Our best Frontier deals on Myrtle Beach to Florida Keys flight tickets

Frontier

Sep 24

MYR9:37 amMyrtle Beach Intl

10h 08m

1 stop

MIA7:45 pmMiami

Sep 30

MIA8:50 pmMiami

12h 02m

1 stop

MYR8:52 amMyrtle Beach Intl

$201

Frontier

Oct 15

MYR9:32 amMyrtle Beach Intl

10h 13m

1 stop

MIA7:45 pmMiami

Oct 17

MIA8:50 pmMiami

11h 57m

1 stop

MYR8:47 amMyrtle Beach Intl

$230

Frontier

Nov 8

MYR9:36 amMyrtle Beach Intl

10h 15m

1 stop

MIA7:51 pmMiami

Nov 14

MIA8:56 pmMiami

11h 55m

1 stop

MYR8:51 amMyrtle Beach Intl

$235

momondo Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Thu 9/24

9:37 am-7:45 pm

1 stop10h 08m

Miami

Wed 9/30

8:50 pm-8:52 am

1 stop12h 02m

$201

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Thu 10/15

9:32 am-7:45 pm

1 stop10h 13m

Miami

Sat 10/17

8:50 pm-8:47 am

1 stop11h 57m

$230

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Sun 11/8

9:36 am-7:51 pm

1 stop10h 15m

Miami

Sat 11/14

8:56 pm-8:51 am

1 stop11h 55m

$235

Quickest round-trip

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Thu 12/10

8:35 pm-12:42 am

1 stop4h 07m

Miami

Thu 12/17

11:30 am-3:44 pm

1 stop4h 14m

$309

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Wed 11/18

10:17 am-3:26 pm

1 stop5h 09m

Miami

Mon 11/23

6:00 am-10:22 am

1 stop4h 22m

$309

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Mon 10/19

6:58 pm-11:31 pm

1 stop4h 33m

Miami

Wed 10/28

6:04 am-10:07 am

1 stop4h 03m

$309

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Tue 10/6

2:16 pm-7:43 pm

1 stop5h 27m

Miami

Wed 10/7

6:04 am-10:07 am

1 stop4h 03m

$309

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Wed 2/24

10:55 am-3:40 pm

1 stop4h 45m

Miami

Mon 3/1

6:00 am-10:08 am

1 stop4h 08m

$309

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Thu 9/24

2:30 pm-10:10 pm

2 stops7h 40m

Miami

Wed 9/30

11:50 am-7:15 pm

1 stop7h 25m

$314

Myrtle BeachMiami

MYR Myrtle Beach Intl - MIA Miami

MYRMIA

Myrtle Beach Intl

Tue 10/20

2:10 pm-10:10 pm

2 stops8h 00m

Miami

Sat 10/24

6:45 am-5:15 pm

2 stops10h 30m

$319

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Florida Keys?

The month of August is another great option to travel to Florida Keys, with average flight prices from Myrtle Beach averaging around $341.

How far in advance should I book a flight from Myrtle Beach to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $394 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Myrtle Beach for as low as $277 on momondo.

Can stopping save me money on Myrtle Beach to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Florida Keys.

Cheap Myrtle Beach to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Florida Keys

Best Price Found	$131
Fastest flight time	4h 29m
Direct flights	None

The best one-way flight to Florida Keys from Myrtle Beach in the past 72 hours is $131. The best round-trip flight deal from Myrtle Beach to Florida Keys found on momondo in the last 72 hours is $201.

The fastest flight from Myrtle Beach to Florida Keys takes 4h 29m

There are no direct flights from Myrtle Beach to Florida Keys. There are no popular flight routes from Myrtle Beach to Florida Keys.

Search flight deals

Frequently asked questions about flying from Myrtle Beach to Florida Keys

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Florida Keys?
Prices for flights from Myrtle Beach Intl Airport to Florida Keys are updated daily.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Florida Keys?
As of August 2026, there are 3 operators available to choose from for flights from Myrtle Beach Intl Airport to Florida Keys.
How old do you have to be to fly from Myrtle Beach Intl Airport to Florida Keys?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Myrtle Beach to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Myrtle Beach to Florida Keys is Airbus A220-300, representing 27.53% of all bookings. The subsequent popular models are Airbus A320-100/200 at 21.25%, Airbus A319 at 7.44%, and Embraer 175 (Enhanced Winglets) at 6.62%.

Best airlines flying from Myrtle Beach to Florida Keys

Compare and see reviews for airlines that fly from Myrtle Beach to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $302	Free Cancellation	Rating 7.8 8,538 reviews		Search Delta flights
American Airlines	PriceFrom $302	Free Cancellation	Rating 7.1 12,026 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from Myrtle Beach.

Can I find flights from Myrtle Beach to Florida Keys with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florida Keys from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Florida Keys.

I’m not ready to book a flight from Myrtle Beach to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.