What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Myrtle Beach Intl to Florida Keys?

Frontier and Spirit Airlines are the most popular carriers operating from Myrtle Beach Intl to Florida Keys

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Florida Keys?

Prices for flights from Myrtle Beach Intl Airport to Florida Keys are updated daily.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Florida Keys?

As of April 2026, there are 3 operators available to choose from for flights from Myrtle Beach Intl Airport to Florida Keys.

How old do you have to be to fly from Myrtle Beach Intl Airport to Florida Keys?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$83 Cheap Flights from Myrtle Beach to Florida Keys in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Myrtle Beach to Florida Keys

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:09 pm - 10:34 pm

MYR

MIA

7h 25m

1 stop

7:00 am - 4:44 pm

MIA

MYR

9h 44m

1 stop

$140Frontier

Mon, Apr 27 - Fri, May 1

5:29 pm - 3:09 pm

MYR

MIA

21h 40m

1 stop

7:00 am - 4:44 pm

MIA

MYR

9h 44m

1 stop

$151Frontier

Fri, May 1 - Mon, May 4

3:09 pm - 10:34 pm

MYR

MIA

7h 25m

1 stop

7:00 am - 4:44 pm

MIA

MYR

9h 44m

1 stop

$160Frontier

Mon, Apr 27 - Fri, May 1

5:29 pm - 2:07 pm

MYR

MIA

20h 38m

1 stop

6:15 am - 4:44 pm

MIA

MYR

10h 29m

1 stop

$191Frontier

Thu, Apr 23 - Sun, Apr 26

8:43 pm - 4:22 pm

MYR

MIA

19h 39m

1 stop

4:05 pm - 2:44 pm

MIA

MYR

22h 39m

1 stop

$193Spirit Airlines

Sat, Apr 25 - Thu, Apr 30

8:43 pm - 1:04 pm

MYR

MIA

16h 21m

1 stop

5:49 pm - 8:13 am

MIA

MYR

14h 24m

1 stop

$204Spirit Airlines

Tue, Apr 21 - Wed, Apr 22

9:50 pm - 9:52 pm

MYR

MIA

24h 02m

1 stop

4:03 pm - 9:46 am

MIA

MYR

17h 43m

1 stop

$207Multiple Airlines

Thu, May 14 - Tue, May 19

9:50 pm - 9:52 pm

MYR

MIA

24h 02m

1 stop

4:03 pm - 9:46 am

MIA

MYR

17h 43m

1 stop

$208Multiple Airlines

Thu, May 7 - Thu, May 14

6:00 am - 10:58 am

MYR

EYW

4h 58m

1 stop

6:00 pm - 11:35 pm

EYW

MYR

5h 35m

1 stop

$303Delta

Tue, Sep 29 - Tue, Oct 6

11:22 am - 6:27 pm

MYR

EYW

7h 05m

2 stops

1:26 pm - 7:00 pm

EYW

MYR

5h 34m

1 stop

$308American Airlines

Tue, Sep 29 - Tue, Oct 6

Frontier flights from Myrtle Beach to Florida Keys

Our best Frontier deals on Myrtle Beach to Florida Keys flight tickets

Frontier

Apr 27

MYR3:09 pmMyrtle Beach Intl

7h 25m

1 stop

MIA10:34 pmMiami

May 1

MIA7:00 amMiami

9h 44m

1 stop

MYR4:44 pmMyrtle Beach Intl

$140

Frontier

May 1

MYR5:29 pmMyrtle Beach Intl

21h 40m

1 stop

MIA3:09 pmMiami

May 4

MIA7:00 amMiami

9h 44m

1 stop

MYR4:44 pmMyrtle Beach Intl

$151

Frontier

Apr 27

MYR3:09 pmMyrtle Beach Intl

7h 25m

1 stop

MIA10:34 pmMiami

May 1

MIA7:00 amMiami

9h 44m

1 stop

MYR4:44 pmMyrtle Beach Intl

$160

Spirit Airlines flights from Myrtle Beach to Florida Keys

Our best Spirit Airlines deals on Myrtle Beach to Florida Keys flight tickets

Spirit Airlines

Apr 25

MYR8:43 pmMyrtle Beach Intl

19h 39m

1 stop

MIA4:22 pmMiami

Apr 30

MIA4:05 pmMiami

22h 39m

1 stop

MYR2:44 pmMyrtle Beach Intl

$193

Spirit Airlines

Apr 21

MYR8:43 pmMyrtle Beach Intl

16h 21m

1 stop

MIA1:04 pmMiami

Apr 22

MIA5:49 pmMiami

14h 24m

1 stop

MYR8:13 amMyrtle Beach Intl

$204

Spirit Airlines

Apr 27

MYR8:43 pmMyrtle Beach Intl

19h 39m

1 stop

MIA4:22 pmMiami

May 1

MIA5:49 pmMiami

22h 01m

1 stop

MYR3:50 pmMyrtle Beach Intl

$210

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 4/27

3:09 pm-10:34 pm

1 stop7h 25m

Miami

Fri 5/1

7:00 am-4:44 pm

1 stop9h 44m

$140

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 5/1

5:29 pm-3:09 pm

1 stop21h 40m

Miami

Mon 5/4

7:00 am-4:44 pm

1 stop9h 44m

$151

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 4/27

3:09 pm-10:34 pm

1 stop7h 25m

Miami

Fri 5/1

7:00 am-4:44 pm

1 stop9h 44m

$160

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 4/23

5:29 pm-2:07 pm

1 stop20h 38m

Miami

Sun 4/26

6:15 am-4:44 pm

1 stop10h 29m

$191

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 4/25

8:43 pm-4:22 pm

1 stop19h 39m

Miami

Thu 4/30

4:05 pm-2:44 pm

1 stop22h 39m

$193

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 4/21

8:43 pm-1:04 pm

1 stop16h 21m

Miami

Wed 4/22

5:49 pm-8:13 am

1 stop14h 24m

$204

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 5/14

9:50 pm-9:52 pm

1 stop24h 02m

Miami

Tue 5/19

4:03 pm-9:46 am

1 stop17h 43m

$207

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 5/7

9:50 pm-9:52 pm

1 stop24h 02m

Miami

Thu 5/14

4:03 pm-9:46 am

1 stop17h 43m

$208

Quickest round-trip

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 9/29

6:00 am-10:58 am

1 stop4h 58m

Key West

Tue 10/6

6:00 pm-11:35 pm

1 stop5h 35m

$303

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 9/29

11:22 am-6:27 pm

2 stops7h 05m

Key West

Tue 10/6

1:26 pm-7:00 pm

1 stop5h 34m

$308

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Florida Keys?

The month of October is another great option to travel to Florida Keys, with average flight prices from Myrtle Beach averaging around $291.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $356 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Myrtle Beach for as low as $189 on momondo.

Can stopping save me money on Myrtle Beach to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Florida Keys.

Cheap Myrtle Beach to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Florida Keys

Fastest flight time	4h 45m
Direct flights	None

The fastest flight from Myrtle Beach to Florida Keys takes 4h 45m

There are no direct flights from Myrtle Beach to Florida Keys. There are no popular flight routes from Myrtle Beach to Florida Keys.

Search flight deals

Frequently asked questions about flying from Myrtle Beach to Florida Keys

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Florida Keys?
Prices for flights from Myrtle Beach Intl Airport to Florida Keys are updated daily.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Florida Keys?
As of April 2026, there are 3 operators available to choose from for flights from Myrtle Beach Intl Airport to Florida Keys.
How old do you have to be to fly from Myrtle Beach Intl Airport to Florida Keys?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Myrtle Beach to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Myrtle Beach to Florida Keys is Airbus A320-100/200, representing 28.23% of all bookings. The subsequent popular models are Airbus A220-300 at 22.76%, Embraer 175 (Enhanced Winglets) at 8.56%, and Canadair (Bombardier) Regional Jet 900 at 5.64%.

Best airlines flying from Myrtle Beach to Florida Keys

Compare and see reviews for airlines that fly from Myrtle Beach to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,406 reviews		Search Delta flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,572 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from Myrtle Beach.

Can I find flights from Myrtle Beach to Florida Keys with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florida Keys from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Florida Keys.

I’m not ready to book a flight from Myrtle Beach to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.