What is the cheapest airline that flies from Myrtle Beach Intl to Florida Keys?

Spirit Airlines and Frontier are the most popular carriers operating from Myrtle Beach Intl to Florida Keys

What airlines fly to Florida Keys?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florida Keys from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 72% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Florida Keys?

Prices for flights from Myrtle Beach Intl Airport to Florida Keys are updated daily.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Florida Keys?

As of February 2026, there are 3 operators available to choose from for flights from Myrtle Beach Intl Airport to Florida Keys.

How old do you have to be to fly from Myrtle Beach Intl Airport to Florida Keys?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$82 Cheap Flights from Myrtle Beach to Florida Keys in 2026

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Find the cheapest flights from Myrtle Beach to Florida Keys

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:25 pm - 11:06 pm

MYR

MIA

7h 41m

1 stop

7:00 am - 4:44 pm

MIA

MYR

9h 44m

1 stop

$160Frontier

Sat, Apr 11 - Fri, Apr 17

6:39 pm - 3:09 pm

MYR

MIA

20h 30m

1 stop

7:00 am - 5:44 pm

MIA

MYR

10h 44m

1 stop

$171Frontier

Fri, Apr 17 - Mon, Apr 20

9:42 am - 7:22 pm

MYR

MIA

9h 40m

1 stop

7:00 am - 4:44 pm

MIA

MYR

9h 44m

1 stop

$173Multiple Airlines

Thu, Apr 16 - Mon, Apr 20

9:42 am - 7:22 pm

MYR

MIA

9h 40m

1 stop

10:55 am - 5:48 pm

MIA

MYR

6h 53m

1 stop

$174Spirit Airlines

Thu, Apr 23 - Sun, Apr 26

10:01 am - 7:16 pm

MYR

MIA

9h 15m

1 stop

10:55 am - 5:48 pm

MIA

MYR

6h 53m

1 stop

$175Spirit Airlines

Tue, Apr 14 - Wed, Apr 29

5:29 pm - 3:09 pm

MYR

MIA

21h 40m

1 stop

10:55 am - 5:48 pm

MIA

MYR

6h 53m

1 stop

$178Multiple Airlines

Fri, Apr 17 - Sat, Apr 25

7:26 pm - 9:44 am

MYR

MIA

14h 18m

1 stop

10:55 am - 5:48 pm

MIA

MYR

6h 53m

1 stop

$184Spirit Airlines

Wed, Apr 15 - Wed, Apr 22

9:48 pm - 9:44 am

MYR

MIA

11h 56m

1 stop

10:55 am - 5:48 pm

MIA

MYR

6h 53m

1 stop

$191Spirit Airlines

Wed, Apr 15 - Wed, Apr 22

6:01 am - 12:01 pm

MYR

EYW

6h 00m

1 stop

6:34 pm - 10:56 pm

EYW

MYR

4h 22m

1 stop

$251American Airlines

Tue, Mar 17 - Tue, Mar 24

6:54 am - 4:49 pm

MYR

EYW

9h 55m

2 stops

6:34 pm - 10:56 pm

EYW

MYR

4h 22m

1 stop

$256American Airlines

Tue, Mar 17 - Tue, Mar 24

Spirit Airlines flights from Myrtle Beach to Florida Keys

Our best Spirit Airlines deals on Myrtle Beach to Florida Keys flight tickets

Spirit Airlines

Apr 23

MYR9:42 amMyrtle Beach Intl

9h 40m

1 stop

MIA7:22 pmMiami

Apr 26

MIA10:55 amMiami

6h 53m

1 stop

MYR5:48 pmMyrtle Beach Intl

$174

Spirit Airlines

Apr 28

MYR9:42 amMyrtle Beach Intl

9h 40m

1 stop

MIA7:22 pmMiami

Apr 30

MIA10:55 amMiami

6h 53m

1 stop

MYR5:48 pmMyrtle Beach Intl

$175

Spirit Airlines

Apr 15

MYR7:26 pmMyrtle Beach Intl

14h 18m

1 stop

MIA9:44 amMiami

Apr 22

MIA10:55 amMiami

6h 53m

1 stop

MYR5:48 pmMyrtle Beach Intl

$184

Frontier flights from Myrtle Beach to Florida Keys

Our best Frontier deals on Myrtle Beach to Florida Keys flight tickets

Frontier

Apr 11

MYR3:25 pmMyrtle Beach Intl

7h 41m

1 stop

MIA11:06 pmMiami

Apr 17

MIA7:00 amMiami

9h 44m

1 stop

MYR4:44 pmMyrtle Beach Intl

$160

Frontier

Apr 17

MYR6:39 pmMyrtle Beach Intl

20h 30m

1 stop

MIA3:09 pmMiami

Apr 25

MIA10:13 amMiami

7h 01m

1 stop

MYR5:14 pmMyrtle Beach Intl

$171

momondo Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 4/11

3:25 pm-11:06 pm

1 stop7h 41m

Miami

Fri 4/17

7:00 am-4:44 pm

1 stop9h 44m

$160

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 4/17

6:39 pm-3:09 pm

1 stop20h 30m

Miami

Mon 4/20

7:00 am-5:44 pm

1 stop10h 44m

$171

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 4/16

9:42 am-7:22 pm

1 stop9h 40m

Miami

Mon 4/20

7:00 am-4:44 pm

1 stop9h 44m

$173

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 4/23

9:42 am-7:22 pm

1 stop9h 40m

Miami

Sun 4/26

10:55 am-5:48 pm

1 stop6h 53m

$174

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 4/14

10:01 am-7:16 pm

1 stop9h 15m

Miami

Wed 4/29

10:55 am-5:48 pm

1 stop6h 53m

$175

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 4/17

5:29 pm-3:09 pm

1 stop21h 40m

Miami

Sat 4/25

10:55 am-5:48 pm

1 stop6h 53m

$178

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 4/15

7:26 pm-9:44 am

1 stop14h 18m

Miami

Wed 4/22

10:55 am-5:48 pm

1 stop6h 53m

$184

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 4/15

9:48 pm-9:44 am

1 stop11h 56m

Miami

Wed 4/22

10:55 am-5:48 pm

1 stop6h 53m

$191

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/17

6:01 am-12:01 pm

1 stop6h 00m

Key West

Tue 3/24

6:34 pm-10:56 pm

1 stop4h 22m

$251

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/17

6:54 am-4:49 pm

2 stops9h 55m

Key West

Tue 3/24

6:34 pm-10:56 pm

1 stop4h 22m

$256

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Florida Keys?

The month of May is another great option to travel to Florida Keys, with average flight prices from Myrtle Beach averaging around $298.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $359 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Myrtle Beach for as low as $186 on momondo.

Can stopping save me money on Myrtle Beach to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Florida Keys.

Cheap Myrtle Beach to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Florida Keys

Fastest flight time	4h 21m
Direct flights	None

The fastest flight from Myrtle Beach to Florida Keys takes 4h 21m

There are no direct flights from Myrtle Beach to Florida Keys. There are no popular flight routes from Myrtle Beach to Florida Keys.

Search flight deals

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Florida Keys?
Prices for flights from Myrtle Beach Intl Airport to Florida Keys are updated daily.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Florida Keys?
As of February 2026, there are 3 operators available to choose from for flights from Myrtle Beach Intl Airport to Florida Keys.
How old do you have to be to fly from Myrtle Beach Intl Airport to Florida Keys?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Myrtle Beach to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Myrtle Beach to Florida Keys is Airbus A220-300, representing 21.80% of all bookings. The subsequent popular models are Airbus A320-100/200 at 19.99%, Embraer 175 (Enhanced Winglets) at 11.36%, and Airbus A321neo at 6.81%.

Best airlines flying from Myrtle Beach to Florida Keys

Compare and see reviews for airlines that fly from Myrtle Beach to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,228 reviews		Search Delta flights
American Airlines	PriceFrom $258	Free Cancellation	Rating 7.2 11,334 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from Myrtle Beach.

Can I find flights from Myrtle Beach to Florida Keys with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florida Keys from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Florida Keys.

I’m not ready to book a flight from Myrtle Beach to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.