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Cheap flights from Myrtle Beach to Florida Keys from $75

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Florida Keys departing on 1/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to Florida Keys

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:54 am - 1:01 pm
MYR
-
MIA
6h 07m1 stop
American Airlines Logo
5:30 pm - 10:56 pm
MIA
-
MYR
5h 26m1 stop
$159American Airlines
Tue, Mar 10 - Tue, Mar 17
American Airlines Logo
6:23 pm - 11:43 pm
MYR
-
MIA
5h 20m1 stop
American Airlines Logo
3:28 pm - 8:45 pm
MIA
-
MYR
5h 17m1 stop
$161American Airlines
Thu, Feb 19 - Tue, Feb 24
American Airlines Logo
6:23 am - 12:48 pm
MYR
-
MIA
6h 25m1 stop
American Airlines Logo
6:45 pm - 11:15 pm
MIA
-
MYR
4h 30m1 stop
$163American Airlines
Mon, Feb 2 - Thu, Feb 5
Spirit Airlines Logo
10:00 am - 8:13 pm
MYR
-
MIA
10h 13m1 stop
Spirit Airlines Logo
12:56 pm - 9:04 pm
MIA
-
MYR
8h 08m1 stop
$165Spirit Airlines
Sat, Jan 24 - Sat, Jan 31
Spirit Airlines Logo
10:00 am - 8:13 pm
MYR
-
MIA
10h 13m1 stop
Spirit Airlines Logo
1:24 pm - 11:57 pm
MIA
-
MYR
10h 33m1 stop
$169Spirit Airlines
Tue, Feb 10 - Sat, Feb 14
Spirit Airlines Logo
10:00 am - 8:13 pm
MYR
-
MIA
10h 13m1 stop
Spirit Airlines Logo
1:24 pm - 11:57 pm
MIA
-
MYR
10h 33m1 stop
$170Spirit Airlines
Sat, Feb 7 - Sun, Feb 15
Spirit Airlines Logo
10:00 am - 8:13 pm
MYR
-
MIA
10h 13m1 stop
Spirit Airlines Logo
1:24 pm - 11:57 pm
MIA
-
MYR
10h 33m1 stop
$174Spirit Airlines
Sat, Feb 7 - Sun, Feb 15
Spirit Airlines Logo
10:00 am - 8:13 pm
MYR
-
MIA
10h 13m1 stop
Spirit Airlines Logo
1:24 pm - 11:57 pm
MIA
-
MYR
10h 33m1 stop
$176Spirit Airlines
Mon, Feb 2 - Thu, Feb 12
Multiple Airlines Logo
10:00 am - 11:16 pm
MYR
-
MIA
13h 16m1 stop
Multiple Airlines Logo
6:00 am - 9:03 am
MIA
-
MYR
27h 03m1 stop
$185Multiple Airlines
Sat, Jan 31 - Mon, Feb 2
American Airlines Logo
5:29 pm - 9:47 pm
MYR
-
EYW
4h 18m1 stop
American Airlines Logo
7:08 am - 1:23 pm
EYW
-
MYR
6h 15m1 stop
$265American Airlines
Fri, Jan 23 - Tue, Jan 27

Spirit Airlines flights from Myrtle Beach to Florida Keys

Our best Spirit Airlines deals on Myrtle Beach to Florida Keys flight tickets
Spirit Airlines
Jan 24
MYR10:00 amMyrtle Beach Intl
10h 13m
1 stop
MIA8:13 pmMiami
Jan 31
MIA12:56 pmMiami
8h 08m
1 stop
MYR9:04 pmMyrtle Beach Intl
$165
Find similar
Spirit Airlines
Feb 10
MYR10:00 amMyrtle Beach Intl
10h 13m
1 stop
MIA8:13 pmMiami
Feb 14
MIA1:24 pmMiami
10h 33m
1 stop
MYR11:57 pmMyrtle Beach Intl
$169
Find similar
Spirit Airlines
Feb 7
MYR10:00 amMyrtle Beach Intl
10h 13m
1 stop
MIA8:13 pmMiami
Feb 15
MIA1:24 pmMiami
10h 33m
1 stop
MYR11:57 pmMyrtle Beach Intl
$170
Find similar

American Airlines flights from Myrtle Beach to Florida Keys

Our best American Airlines deals on Myrtle Beach to Florida Keys flight tickets
American Airlines
Mar 10
MYR6:54 amMyrtle Beach Intl
6h 07m
1 stop
MIA1:01 pmMiami
Mar 17
MIA5:30 pmMiami
5h 26m
1 stop
MYR10:56 pmMyrtle Beach Intl
$159
Find similar
American Airlines
Feb 19
MYR6:23 pmMyrtle Beach Intl
5h 20m
1 stop
MIA11:43 pmMiami
Feb 24
MIA3:28 pmMiami
5h 17m
1 stop
MYR8:45 pmMyrtle Beach Intl
$161
Find similar
American Airlines
Feb 2
MYR6:23 amMyrtle Beach Intl
6h 25m
1 stop
MIA12:48 pmMiami
Feb 5
MIA6:45 pmMiami
4h 30m
1 stop
MYR11:15 pmMyrtle Beach Intl
$163
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 3/10

6:54 am-1:01 pm

1 stop6h 07m

Miami

Tue 3/17

5:30 pm-10:56 pm

1 stop5h 26m

$159

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 2/19

6:23 pm-11:43 pm

1 stop5h 20m

Miami

Tue 2/24

3:28 pm-8:45 pm

1 stop5h 17m

$161

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 2/2

6:23 am-12:48 pm

1 stop6h 25m

Miami

Thu 2/5

6:45 pm-11:15 pm

1 stop4h 30m

$163

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 1/24

10:00 am-8:13 pm

1 stop10h 13m

Miami

Sat 1/31

12:56 pm-9:04 pm

1 stop8h 08m

$165

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 2/10

10:00 am-8:13 pm

1 stop10h 13m

Miami

Sat 2/14

1:24 pm-11:57 pm

1 stop10h 33m

$169

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 2/7

10:00 am-8:13 pm

1 stop10h 13m

Miami

Sun 2/15

1:24 pm-11:57 pm

1 stop10h 33m

$170

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 2/7

10:00 am-8:13 pm

1 stop10h 13m

Miami

Sun 2/15

1:24 pm-11:57 pm

1 stop10h 33m

$174

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 2/2

10:00 am-8:13 pm

1 stop10h 13m

Miami

Thu 2/12

1:24 pm-11:57 pm

1 stop10h 33m

$176

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 1/31

10:00 am-11:16 pm

1 stop13h 16m

Miami

Mon 2/2

6:00 am-9:03 am

1 stop27h 03m

$185

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 1/23

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Tue 1/27

7:08 am-1:23 pm

1 stop6h 15m

$265

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida Keys from

How to get the cheapest flight ticket from Myrtle Beach to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of August is another great option to travel to Florida Keys, with average flight prices from Myrtle Beach averaging around $312.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $353 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Myrtle Beach for as low as $217 on momondo.

Can stopping save me money on Myrtle Beach to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Florida Keys.

Cheap Myrtle Beach to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Florida Keys

Fastest flight time

4h 17m

Direct flights

None
The fastest flight from Myrtle Beach to Florida Keys takes 4h 17m
There are no direct flights from Myrtle Beach to Florida Keys. There are no popular flight routes from Myrtle Beach to Florida Keys.
Search flight deals

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Florida Keys?

    Prices for flights from Myrtle Beach Intl Airport to Florida Keys are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Florida Keys?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Florida Keys?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Florida Keys?

Best airlines flying from Myrtle Beach to Florida Keys

Compare and see reviews for airlines that fly from Myrtle Beach to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,022 reviews
Search Delta flights
American AirlinesPriceFrom $263Free CancellationRating
7.2
11,088 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from Myrtle Beach.

Can I find flights from Myrtle Beach to Florida Keys with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florida Keys from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Florida Keys.

I’m not ready to book a flight from Myrtle Beach to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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