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Cheap flights from Myrtle Beach to Florida Keys from $97

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Florida Keys departing on 1/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Myrtle Beach to Florida Keys

Cheap round-trip flights

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Multiple Airlines Logo
9:55 pm - 11:16 pmMYR-MIA
25h 21m1 stop
Multiple Airlines Logo
5:50 pm - 8:58 amMIA-MYR
15h 08m1 stop
$198Multiple Airlines
Find Deal
Fri, Jan 23 - Thu, Jan 29
Multiple Airlines Logo
9:55 pm - 1:14 amMYR-MIA
27h 19m1 stop
Multiple Airlines Logo
2:01 pm - 12:12 pmMIA-MYR
22h 11m2 stops
$212Multiple Airlines
Find Deal
Wed, Jan 28 - Sat, Feb 7
Multiple Airlines Logo
9:55 pm - 1:14 amMYR-MIA
27h 19m1 stop
Multiple Airlines Logo
11:55 am - 2:34 pmMIA-MYR
26h 39m1 stop
$214Multiple Airlines
Find Deal
Wed, Jan 28 - Sat, Feb 7
Spirit Airlines Logo
9:53 am - 8:13 pmMYR-MIA
10h 20m1 stop
Spirit Airlines Logo
4:01 pm - 8:58 amMIA-MYR
16h 57m1 stop
$218Spirit Airlines
Find Deal
Sun, Jan 11 - Fri, Jan 16
Multiple Airlines Logo
9:53 am - 8:13 pmMYR-MIA
10h 20m1 stop
Multiple Airlines Logo
12:09 pm - 12:12 pmMIA-MYR
24h 03m2 stops
$219Multiple Airlines
Find Deal
Sat, Jan 24 - Sat, Jan 31
Spirit Airlines Logo
9:53 am - 8:13 pmMYR-MIA
10h 20m1 stop
Spirit Airlines Logo
12:56 pm - 8:59 pmMIA-MYR
8h 03m1 stop
$222Spirit Airlines
Find Deal
Sat, Jan 24 - Sat, Jan 31
Multiple Airlines Logo
9:55 pm - 11:16 pmMYR-MIA
25h 21m1 stop
Multiple Airlines Logo
7:09 pm - 7:20 pmMIA-MYR
24h 11m2 stops
$224Multiple Airlines
Find Deal
Fri, Jan 23 - Thu, Jan 29
American Airlines Logo
12:05 pm - 6:01 pmMYR-EYW
5h 56m1 stop
American Airlines Logo
8:03 am - 2:18 pmEYW-MYR
6h 15m1 stop
$239American Airlines
Find Deal
Sun, Jan 18 - Sun, Feb 15
Delta Logo
10:33 am - 5:11 pmMYR-EYW
6h 38m1 stop
Delta Logo
12:20 pm - 5:59 pmEYW-MYR
5h 39m1 stop
$244Delta
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Sun, Jan 18 - Thu, Jan 29
American Airlines Logo
5:29 pm - 9:47 pmMYR-EYW
4h 18m1 stop
American Airlines Logo
6:28 pm - 10:59 pmEYW-MYR
4h 31m1 stop
$245American Airlines
Find Deal
Wed, Feb 11 - Wed, Feb 18

Spirit Airlines flights from Myrtle Beach to Florida Keys

Our best Spirit Airlines deals on Myrtle Beach to Florida Keys flight tickets
Spirit Airlines
Jan 11
MYR9:53 amMyrtle Beach Intl
10h 20m
1 stop
MIA8:13 pmMiami
Jan 16
MIA4:01 pmMiami
16h 57m
1 stop
MYR8:58 amMyrtle Beach Intl
$218
Find similar
Spirit Airlines
Jan 24
MYR9:53 amMyrtle Beach Intl
10h 20m
1 stop
MIA8:13 pmMiami
Jan 31
MIA12:56 pmMiami
8h 03m
1 stop
MYR8:59 pmMyrtle Beach Intl
$222
Find similar
Spirit Airlines
Jan 12
MYR9:53 amMyrtle Beach Intl
10h 20m
1 stop
MIA8:13 pmMiami
Jan 17
MIA12:56 pmMiami
8h 03m
1 stop
MYR8:59 pmMyrtle Beach Intl
$225
Find similar

American Airlines flights from Myrtle Beach to Florida Keys

Our best American Airlines deals on Myrtle Beach to Florida Keys flight tickets
American Airlines
Jan 18
MYR12:05 pmMyrtle Beach Intl
5h 56m
1 stop
EYW6:01 pmKey West
Feb 15
EYW8:03 amKey West
6h 15m
1 stop
MYR2:18 pmMyrtle Beach Intl
$239
Find similar
American Airlines
Feb 11
MYR5:29 pmMyrtle Beach Intl
4h 18m
1 stop
EYW9:47 pmKey West
Feb 18
EYW6:28 pmKey West
4h 31m
1 stop
MYR10:59 pmMyrtle Beach Intl
$245
Find similar
American Airlines
Feb 11
MYR5:29 pmMyrtle Beach Intl
4h 18m
1 stop
EYW9:47 pmKey West
Feb 18
EYW7:00 amKey West
6h 27m
2 stops
MYR1:27 pmMyrtle Beach Intl
$250
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 1/23

9:55 pm-11:16 pm

1 stop25h 21m

Miami

Thu 1/29

5:50 pm-8:58 am

1 stop15h 08m

$198

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 1/28

9:55 pm-1:14 am

1 stop27h 19m

Miami

Sat 2/7

2:01 pm-12:12 pm

2 stops22h 11m

$212

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 1/28

9:55 pm-1:14 am

1 stop27h 19m

Miami

Sat 2/7

11:55 am-2:34 pm

1 stop26h 39m

$214

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sun 1/11

9:53 am-8:13 pm

1 stop10h 20m

Miami

Fri 1/16

4:01 pm-8:58 am

1 stop16h 57m

$218

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 1/24

9:53 am-8:13 pm

1 stop10h 20m

Miami

Sat 1/31

12:09 pm-12:12 pm

2 stops24h 03m

$219

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 1/24

9:53 am-8:13 pm

1 stop10h 20m

Miami

Sat 1/31

12:56 pm-8:59 pm

1 stop8h 03m

$222

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 1/23

9:55 pm-11:16 pm

1 stop25h 21m

Miami

Thu 1/29

7:09 pm-7:20 pm

2 stops24h 11m

$224

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 1/18

12:05 pm-6:01 pm

1 stop5h 56m

Key West

Sun 2/15

8:03 am-2:18 pm

1 stop6h 15m

$239

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sun 1/18

10:33 am-5:11 pm

1 stop6h 38m

Key West

Thu 1/29

12:20 pm-5:59 pm

1 stop5h 39m

$244

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 2/11

5:29 pm-9:47 pm

1 stop4h 18m

Key West

Wed 2/18

6:28 pm-10:59 pm

1 stop4h 31m

$245

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida Keys from

How to get the cheapest flight ticket from Myrtle Beach to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of August is another great option to travel to Florida Keys, with average flight prices from Myrtle Beach averaging around $312.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Myrtle Beach to Florida Keys is on a Monday when prices can be found for as low as $162. The most expensive day to fly to Florida Keys is Friday, with ticket prices averaging around $293.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is at noon. momondo users have found flights departing from Myrtle Beach to Florida Keys at noon for as low as $194. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the afternoon are often more expensive with an average ticket price of $357.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $364 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Myrtle Beach for as low as $243 on momondo.

Can stopping save me money on Myrtle Beach to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Florida Keys.

Cheap Myrtle Beach to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Florida Keys

Direct flights

None
There are no direct flights from Myrtle Beach to Florida Keys. There are no popular flight routes from Myrtle Beach to Florida Keys.
Search flight deals

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Florida Keys?

    Prices for flights from Myrtle Beach Intl Airport to Florida Keys are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Florida Keys?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Florida Keys?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Florida Keys?

Best airlines flying from Myrtle Beach to Florida Keys

Compare and see reviews for airlines that fly from Myrtle Beach to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $223Free CancellationRating
7.9
8,003 reviews
Search Delta flights
American AirlinesPriceFrom $279Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Florida Keys?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florida Keys from Myrtle Beach.

Can I find flights from Myrtle Beach to Florida Keys with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florida Keys from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Florida Keys?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Florida Keys.

I’m not ready to book a flight from Myrtle Beach to Florida Keys right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Florida Keys flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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