What airlines fly to Roanoke?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Roanoke from Missouri according to our data. Delta is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Roanoke. Keep in mind that there are 3 different airlines that fly to Roanoke on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Missouri to Roanoke?

Delta, American Airlines, and United Airlines are the most popular carriers operating from Missouri to Roanoke

How long does it take to fly to Roanoke?

Average flight duration from Missouri to Roanoke depends on which airport you fly into and out of. Flying from Kansas City to Greensboro is 3h 58m on average, while flying from St. Louis to Greensboro is 3h 59m on average. Greensboro is the most popular airport in Roanoke.

When did momondo last update prices for flights from Missouri to Roanoke Airport?

Prices for flights from Missouri to Roanoke Airport were last updated today.

How many operators does momondo search for flights from Missouri to Roanoke Airport?

There are 3 operators available for flights from Missouri to Roanoke Airport as of December 2025.

How old do you have to be to fly from Missouri to Roanoke Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Roanoke Airport.

What documentation or ID do you need to fly to Roanoke Airport?

The required travel and health documents for your Roanoke Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Roanoke Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$249 Cheap Flights from Missouri to Roanoke in 2025/26

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Missouri to Roanoke

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:55 pm - 12:04 am

STL

ROA

4h 09m1 stop

6:00 am - 11:05 am

ROA

STL

6h 05m1 stop

$279Delta

Fri, Jan 9 - Sun, Jan 11

11:17 am - 5:03 pm

COU

ROA

4h 46m1 stop

6:45 am - 10:42 am

ROA

COU

4h 57m1 stop

$328United Airlines

Sat, Jan 24 - Tue, Jan 27

8:45 am - 9:11 pm

COU

ROA

11h 26m2 stops

6:45 am - 10:42 am

ROA

COU

4h 57m1 stop

$334United Airlines

Sat, Jan 24 - Tue, Jan 27

8:30 am - 2:09 pm

STL

ROA

4h 39m1 stop

12:40 pm - 5:43 pm

ROA

STL

6h 03m1 stop

$339United Airlines

Wed, Jan 21 - Sat, Jan 24

12:35 pm - 7:31 pm

MCI

ROA

5h 56m1 stop

6:45 am - 10:32 am

ROA

MCI

4h 47m1 stop

$339United Airlines

Wed, Jan 28 - Sat, Jan 31

8:45 am - 9:11 pm

COU

ROA

11h 26m2 stops

10:15 am - 8:33 pm

ROA

COU

11h 18m2 stops

$339United Airlines

Sat, Jan 24 - Tue, Jan 27

6:52 am - 12:09 pm

STL

ROA

4h 17m1 stop

1:56 pm - 6:34 pm

ROA

STL

5h 38m1 stop

$357American Airlines

Tue, Jan 6 - Sat, Jan 10

6:23 pm - 12:04 am

MCI

ROA

4h 41m1 stop

6:00 am - 12:44 pm

ROA

MCI

7h 44m1 stop

$374Delta

Fri, Jan 16 - Sun, Jan 18

6:31 am - 11:51 am

STL

ROA

4h 20m1 stop

6:00 am - 11:49 am

ROA

STL

6h 49m1 stop

$441American Airlines

Fri, Jun 5 - Sun, Jun 7

3:54 pm - 11:42 pm

STL

ROA

6h 48m1 stop

5:14 pm - 11:12 pm

ROA

STL

6h 58m1 stop

$460American Airlines

Sat, Jan 17 - Mon, Jan 19

Delta flights from Missouri to Roanoke

Our best Delta deals on Missouri to Roanoke flight tickets

Delta

Jan 9

STL6:55 pmLambert-St Louis

4h 09m

1 stop

ROA12:04 amRoanoke

Jan 11

ROA6:00 amRoanoke

6h 05m

1 stop

STL11:05 amLambert-St Louis

$279

Find similar

Delta

Dec 25

STL1:22 pmLambert-St Louis

5h 04m

1 stop

ROA7:26 pmRoanoke

Dec 27

ROA7:03 pmRoanoke

5h 39m

1 stop

STL11:42 pmLambert-St Louis

$353

Find similar

Delta

Jan 16

MCI6:23 pmKansas City

4h 41m

1 stop

ROA12:04 amRoanoke

Jan 18

ROA6:00 amRoanoke

7h 44m

1 stop

MCI12:44 pmKansas City

$374

Find similar

American Airlines flights from Missouri to Roanoke

Our best American Airlines deals on Missouri to Roanoke flight tickets

American Airlines

Jan 6

STL6:52 amLambert-St Louis

4h 17m

1 stop

ROA12:09 pmRoanoke

Jan 10

ROA1:56 pmRoanoke

5h 38m

1 stop

STL6:34 pmLambert-St Louis

$357

Find similar

American Airlines

Jun 5

STL6:31 amLambert-St Louis

4h 20m

1 stop

ROA11:51 amRoanoke

Jun 7

ROA5:04 amRoanoke

3h 55m

1 stop

STL7:59 amLambert-St Louis

$441

Find similar

American Airlines

Jan 17

STL3:54 pmLambert-St Louis

6h 48m

1 stop

ROA11:42 pmRoanoke

Jan 19

ROA5:14 pmRoanoke

6h 58m

1 stop

STL11:12 pmLambert-St Louis

$460

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisRoanoke

STL - ROA

STLROA

Lambert-St Louis

Fri 1/9

6:55 pm-12:04 am

1 stop4h 09m

Roanoke

Sun 1/11

6:00 am-11:05 am

1 stop6h 05m

$279

ColumbiaRoanoke

COU - ROA

COUROA

Columbia Regional

Sat 1/24

11:17 am-5:03 pm

1 stop4h 46m

Roanoke

Tue 1/27

6:45 am-10:42 am

1 stop4h 57m

$328

ColumbiaRoanoke

COU - ROA

COUROA

Columbia Regional

Sat 1/24

8:45 am-9:11 pm

2 stops11h 26m

Roanoke

Tue 1/27

6:45 am-10:42 am

1 stop4h 57m

$334

St. LouisRoanoke

STL - ROA

STLROA

Lambert-St Louis

Wed 1/21

8:30 am-2:09 pm

1 stop4h 39m

Roanoke

Sat 1/24

12:40 pm-5:43 pm

1 stop6h 03m

$339

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Wed 1/28

12:35 pm-7:31 pm

1 stop5h 56m

Roanoke

Sat 1/31

6:45 am-10:32 am

1 stop4h 47m

$339

ColumbiaRoanoke

COU - ROA

COUROA

Columbia Regional

Sat 1/24

8:45 am-9:11 pm

2 stops11h 26m

Roanoke

Tue 1/27

10:15 am-8:33 pm

2 stops11h 18m

$339

St. LouisRoanoke

STL - ROA

STLROA

Lambert-St Louis

Tue 1/6

6:52 am-12:09 pm

1 stop4h 17m

Roanoke

Sat 1/10

1:56 pm-6:34 pm

1 stop5h 38m

$357

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Fri 1/16

6:23 pm-12:04 am

1 stop4h 41m

Roanoke

Sun 1/18

6:00 am-12:44 pm

1 stop7h 44m

$374

St. LouisRoanoke

STL - ROA

STLROA

Lambert-St Louis

Fri 6/5

6:31 am-11:51 am

1 stop4h 20m

Roanoke

Sun 6/7

6:00 am-11:49 am

1 stop6h 49m

$441

St. LouisRoanoke

STL - ROA

STLROA

Lambert-St Louis

Sat 1/17

3:54 pm-11:42 pm

1 stop6h 48m

Roanoke

Mon 1/19

5:14 pm-11:12 pm

1 stop6h 58m

$460

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Roanoke?

The month of January is, on average, the cheapest month to fly to Roanoke from Missouri, with most prices found around $248. If you aren’t able to travel to Roanoke during the month of January, then flying in July is also cheap. Prices for this month can be found on momondo for an average of $254.

What is the cheapest day to depart on your flight to Roanoke?

Our data shows that Monday is the least expensive day to fly to Roanoke. Tickets to fly out on this day can be as low as $323. Flights from Missouri to Roanoke on a Saturday will generally be more expensive and average around $362. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Roanoke?

Our most recent data shows that the best time of day to fly to Roanoke is in the evening. Flights from Missouri to Roanoke during this time can be as low as $330. In contrast, the most expensive time of day to depart to Roanoke is at noon when prices are around $368.

Cheap Missouri to Roanoke flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Roanoke

Fastest flight time	4h 09m
Direct flights	None

The fastest flight from Missouri to Roanoke takes 4h 09m

There are no direct flights from Missouri to Roanoke. There are no popular flight routes from Missouri to Roanoke.

Search flight deals

When did momondo last update prices for flights from Missouri to Roanoke Airport?
Prices for flights from Missouri to Roanoke Airport were last updated today.
How many operators does momondo search for flights from Missouri to Roanoke Airport?
There are 3 operators available for flights from Missouri to Roanoke Airport as of December 2025.
How old do you have to be to fly from Missouri to Roanoke Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Roanoke Airport.
What documentation or ID do you need to fly to Roanoke Airport?
The required travel and health documents for your Roanoke Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Roanoke Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Roanoke

Compare and see reviews for airlines that fly from Missouri to Roanoke with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $224	Free Cancellation	Rating 7.2 11,054 reviews	Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 8,014 reviews	Search Delta flights
United Airlines	PriceFrom $258	Free Cancellation	Rating 7.4 9,105 reviews	Search United Airlines flights

Salem

Blacksburg

Christiansburg

Radford

Rocky Mount

Lafayette

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Roanoke?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Missouri to Roanoke. momondo saves you time and could save you money on your trip.

Can I find flights from Missouri to Roanoke with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Roanoke from Missouri with this policy.

How can momondo help me find flights from Missouri to Roanoke?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Roanoke from Missouri.

I’m not ready to book a flight from Missouri to Roanoke right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Missouri to Roanoke now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Roanoke and let you know when they change.