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Cheap flights from Missouri to Roanoke from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Roanoke departing on 4/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Missouri to Roanoke

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:26 pm - 11:50 pm
MCI
-
ROA
5h 24m
1 stop
Delta Logo
6:00 am - 9:27 am
ROA
-
MCI
4h 27m
1 stop
$327Delta
Tue, Sep 8 - Tue, Sep 15
Delta Logo
3:36 pm - 11:50 pm
MCI
-
ROA
7h 14m
1 stop
Delta Logo
11:20 am - 5:30 pm
ROA
-
MCI
7h 10m
1 stop
$328Delta
Thu, Sep 10 - Wed, Sep 16
Delta Logo
6:50 pm - 12:25 am
STL
-
ROA
4h 35m
1 stop
Delta Logo
7:50 pm - 11:36 pm
ROA
-
STL
4h 46m
1 stop
$329Delta
Fri, Apr 17 - Mon, Apr 20
Delta Logo
6:47 pm - 12:25 am
MCI
-
ROA
4h 38m
1 stop
Delta Logo
6:00 am - 9:43 am
ROA
-
MCI
4h 43m
1 stop
$329Delta
Fri, Apr 24 - Fri, May 1
American Airlines Logo
6:06 pm - 12:10 am
MCI
-
ROA
5h 04m
1 stop
American Airlines Logo
5:18 pm - 12:06 am
ROA
-
MCI
7h 48m
2 stops
$333American Airlines
Fri, May 1 - Wed, May 6
American Airlines Logo
2:11 pm - 10:26 pm
MCI
-
ROA
7h 15m
1 stop
American Airlines Logo
5:18 pm - 12:06 am
ROA
-
MCI
7h 48m
2 stops
$334American Airlines
Fri, May 1 - Wed, May 6
United Airlines Logo
11:30 am - 5:05 pm
MCI
-
ROA
4h 35m
1 stop
United Airlines Logo
2:04 pm - 7:45 pm
ROA
-
MCI
6h 41m
1 stop
$339United Airlines
Sat, Apr 11 - Wed, Apr 15
United Airlines Logo
6:00 am - 5:05 pm
MCI
-
ROA
10h 05m
2 stops
United Airlines Logo
6:45 am - 10:27 am
ROA
-
MCI
4h 42m
1 stop
$344United Airlines
Sat, Apr 11 - Wed, Apr 15
United Airlines Logo
6:15 am - 1:29 pm
MCI
-
ROA
6h 14m
1 stop
United Airlines Logo
6:45 am - 10:27 am
ROA
-
MCI
4h 42m
1 stop
$355United Airlines
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
8:54 am - 12:10 am
STL
-
ROA
14h 16m
1 stop
American Airlines Logo
7:28 am - 11:47 am
ROA
-
STL
5h 19m
1 stop
$446American Airlines
Fri, May 1 - Sun, May 3

American Airlines flights from Missouri to Roanoke

Our best American Airlines deals on Missouri to Roanoke flight tickets
American Airlines
May 1
MCI6:06 pmKansas City
5h 04m
1 stop
ROA12:10 amRoanoke
May 6
ROA5:18 pmRoanoke
7h 48m
2 stops
MCI12:06 amKansas City
$333
American Airlines
May 1
MCI2:11 pmKansas City
7h 15m
1 stop
ROA10:26 pmRoanoke
May 6
ROA5:18 pmRoanoke
7h 48m
2 stops
MCI12:06 amKansas City
$334
American Airlines
May 1
STL8:54 amLambert-St Louis
14h 16m
1 stop
ROA12:10 amRoanoke
May 3
ROA7:28 amRoanoke
5h 19m
1 stop
STL11:47 amLambert-St Louis
$446

United Airlines flights from Missouri to Roanoke

Our best United Airlines deals on Missouri to Roanoke flight tickets
United Airlines
Apr 11
MCI11:30 amKansas City
4h 35m
1 stop
ROA5:05 pmRoanoke
Apr 15
ROA2:04 pmRoanoke
6h 41m
1 stop
MCI7:45 pmKansas City
$339
United Airlines
Apr 11
MCI6:00 amKansas City
10h 05m
2 stops
ROA5:05 pmRoanoke
Apr 15
ROA6:45 amRoanoke
4h 42m
1 stop
MCI10:27 amKansas City
$344
United Airlines
Apr 9
MCI6:15 amKansas City
6h 14m
1 stop
ROA1:29 pmRoanoke
Apr 12
ROA6:45 amRoanoke
4h 42m
1 stop
MCI10:27 amKansas City
$355

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 28, 2026.
Use the filters below to find and compare flights from Missouri to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Tue 9/8

5:26 pm-11:50 pm

1 stop5h 24m

Roanoke

Tue 9/15

6:00 am-9:27 am

1 stop4h 27m

$327

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Thu 9/10

3:36 pm-11:50 pm

1 stop7h 14m

Roanoke

Wed 9/16

11:20 am-5:30 pm

1 stop7h 10m

$328
Quickest round-trip

St. LouisRoanoke

STL - ROA

STLROA

Lambert-St Louis

Fri 4/17

6:50 pm-12:25 am

1 stop4h 35m

Roanoke

Mon 4/20

7:50 pm-11:36 pm

1 stop4h 46m

$329

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Fri 4/24

6:47 pm-12:25 am

1 stop4h 38m

Roanoke

Fri 5/1

6:00 am-9:43 am

1 stop4h 43m

$329

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Fri 5/1

6:06 pm-12:10 am

1 stop5h 04m

Roanoke

Wed 5/6

5:18 pm-12:06 am

2 stops7h 48m

$333

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Fri 5/1

2:11 pm-10:26 pm

1 stop7h 15m

Roanoke

Wed 5/6

5:18 pm-12:06 am

2 stops7h 48m

$334

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Sat 4/11

11:30 am-5:05 pm

1 stop4h 35m

Roanoke

Wed 4/15

2:04 pm-7:45 pm

1 stop6h 41m

$339

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Sat 4/11

6:00 am-5:05 pm

2 stops10h 05m

Roanoke

Wed 4/15

6:45 am-10:27 am

1 stop4h 42m

$344

Kansas CityRoanoke

MCI - ROA

MCIROA

Kansas City

Thu 4/9

6:15 am-1:29 pm

1 stop6h 14m

Roanoke

Sun 4/12

6:45 am-10:27 am

1 stop4h 42m

$355

St. LouisRoanoke

STL - ROA

STLROA

Lambert-St Louis

Fri 5/1

8:54 am-12:10 am

1 stop14h 16m

Roanoke

Sun 5/3

7:28 am-11:47 am

1 stop5h 19m

$446

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Roanoke from

How to get the cheapest flight ticket from Missouri to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Missouri to Roanoke?

United Airlines is the most popular carrier operating from Missouri to Roanoke

What airlines fly to Roanoke?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Roanoke from Missouri according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Roanoke. Keep in mind that there are 3 different airlines that fly to Roanoke on a routine basis, so you have a few additional options to choose from.

Cheap Missouri to Roanoke flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Roanoke

Fastest flight time

4h 33m

Direct flights

None
The fastest flight from Missouri to Roanoke takes 4h 33m
There are no direct flights from Missouri to Roanoke. There are no popular flight routes from Missouri to Roanoke.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Roanoke Airport?

    Prices for flights from Missouri to Roanoke Airport were last updated today.

  • How many operators does momondo search for flights from Missouri to Roanoke Airport?

  • How old do you have to be to fly from Missouri to Roanoke Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Roanoke Airport.

  • What documentation or ID do you need to fly to Roanoke Airport?

    The required travel and health documents for your Roanoke Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Roanoke Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Roanoke

Compare and see reviews for airlines that fly from Missouri to Roanoke with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,356 reviews
Search Delta flights
American AirlinesPriceFrom $224Free CancellationRating
7.1
11,520 reviews
Search American Airlines flights
United AirlinesPriceFrom $259Free CancellationRating
7.4
9,499 reviews
Search United Airlines flights

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Blacksburg
Salem
Christiansburg
Radford
Rocky Mount

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Roanoke?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Missouri to Roanoke. momondo saves you time and could save you money on your trip.

Can I find flights from Missouri to Roanoke with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Roanoke from Missouri with this policy.

How can momondo help me find flights from Missouri to Roanoke?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Roanoke from Missouri.

I’m not ready to book a flight from Missouri to Roanoke right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Missouri to Roanoke now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Roanoke and let you know when they change.

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