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Cheap flights from Missouri to Panama City from $79

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama City departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Missouri to Panama City

Cheap round-trip flights

Southwest Logo
8:05 am - 9:50 amSTL-ECP
1h 45mnonstop
Southwest Logo
2:00 pm - 3:50 pmECP-STL
1h 50mnonstop
$157Southwest
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Sun, Oct 5 - Thu, Oct 9
Delta Logo
5:11 pm - 11:06 pmSTL-ECP
5h 55m1 stop
Delta Logo
5:02 pm - 10:02 pmECP-STL
5h 00m1 stop
$177Delta
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Wed, Sep 3 - Tue, Sep 9
Southwest Logo
1:20 pm - 8:05 pmSTL-ECP
6h 45m1 stop
Southwest Logo
3:15 pm - 5:05 pmECP-STL
1h 50mnonstop
$178Southwest
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Wed, Sep 3 - Sat, Sep 6
American Airlines Logo
6:00 am - 2:20 pmSTL-ECP
8h 20m1 stop
American Airlines Logo
6:06 pm - 11:07 pmECP-STL
5h 01m1 stop
$181American Airlines
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Wed, Sep 10 - Wed, Sep 10
Southwest Logo
3:10 pm - 4:55 pmSTL-ECP
1h 45mnonstop
Southwest Logo
3:15 pm - 5:05 pmECP-STL
1h 50mnonstop
$187Southwest
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Mon, Sep 8 - Sat, Sep 20
American Airlines Logo
7:23 am - 5:36 pmSTL-ECP
10h 13m2 stops
American Airlines Logo
3:29 pm - 9:10 pmECP-STL
5h 41m1 stop
$192American Airlines
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Tue, Sep 9 - Tue, Sep 16
Southwest Logo
3:10 pm - 4:55 pmSTL-ECP
1h 45mnonstop
Southwest Logo
5:05 pm - 8:20 pmECP-STL
3h 15m1 stop
$197Southwest
Find Deal
Mon, Sep 29 - Sat, Oct 4
Delta Logo
5:15 pm - 11:10 pmSTL-ECP
5h 55m1 stop
Delta Logo
6:17 pm - 11:41 pmECP-STL
5h 24m1 stop
$202Delta
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Tue, Oct 21 - Mon, Oct 27
United Airlines Logo
9:17 am - 8:16 pmSTL-ECP
10h 59m2 stops
United Airlines Logo
11:09 am - 6:58 pmECP-STL
7h 49m1 stop
$218United Airlines
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Sat, Sep 6 - Wed, Sep 17
United Airlines Logo
8:20 am - 4:20 pmSTL-ECP
8h 00m1 stop
United Airlines Logo
11:09 am - 11:44 pmECP-STL
12h 35m2 stops
$274United Airlines
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Wed, Sep 10 - Wed, Sep 17

Delta flights from Missouri to Panama City, Florida

Our best Delta deals on Missouri to Panama City, Florida flight tickets
Delta
Sep 3
STL5:11 pmLambert-St Louis
5h 55m
1 stop
ECP11:06 pmPanama City NW Florida Beaches
Sep 9
ECP5:02 pmPanama City NW Florida Beaches
5h 00m
1 stop
STL10:02 pmLambert-St Louis
$177
Find similar
Delta
Oct 21
STL5:15 pmLambert-St Louis
5h 55m
1 stop
ECP11:10 pmPanama City NW Florida Beaches
Oct 27
ECP6:17 pmPanama City NW Florida Beaches
5h 24m
1 stop
STL11:41 pmLambert-St Louis
$202
Find similar
Delta
Oct 19
STL6:00 amLambert-St Louis
6h 30m
1 stop
ECP12:30 pmPanama City NW Florida Beaches
Oct 23
ECP6:17 pmPanama City NW Florida Beaches
5h 24m
1 stop
STL11:41 pmLambert-St Louis
$208
Find similar

American Airlines flights from Missouri to Panama City, Florida

Our best American Airlines deals on Missouri to Panama City, Florida flight tickets
American Airlines
Sep 10
STL6:00 amLambert-St Louis
8h 20m
1 stop
ECP2:20 pmPanama City NW Florida Beaches
Sep 10
ECP6:06 pmPanama City NW Florida Beaches
5h 01m
1 stop
STL11:07 pmLambert-St Louis
$181
Find similar
American Airlines
Sep 9
STL7:23 amLambert-St Louis
10h 13m
2 stops
ECP5:36 pmPanama City NW Florida Beaches
Sep 16
ECP3:29 pmPanama City NW Florida Beaches
5h 41m
1 stop
STL9:10 pmLambert-St Louis
$192
Find similar
American Airlines
Aug 28
STL6:02 amLambert-St Louis
6h 03m
1 stop
ECP12:05 pmPanama City NW Florida Beaches
Sep 4
ECP3:29 pmPanama City NW Florida Beaches
5h 41m
1 stop
STL9:10 pmLambert-St Louis
$217
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 12, 2025.
Use the filters below to find and compare flights from Missouri to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Sun 10/5

8:05 am-9:50 am

Nonstop1h 45m

Panama City NW Florida Beaches

Thu 10/9

2:00 pm-3:50 pm

Nonstop1h 50m

$157

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 9/3

5:11 pm-11:06 pm

1 stop5h 55m

Panama City NW Florida Beaches

Tue 9/9

5:02 pm-10:02 pm

1 stop5h 00m

$177

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 9/3

1:20 pm-8:05 pm

1 stop6h 45m

Panama City NW Florida Beaches

Sat 9/6

3:15 pm-5:05 pm

Nonstop1h 50m

$178

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 9/10

6:00 am-2:20 pm

1 stop8h 20m

Panama City NW Florida Beaches

Wed 9/10

6:06 pm-11:07 pm

1 stop5h 01m

$181

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 9/8

3:10 pm-4:55 pm

Nonstop1h 45m

Panama City NW Florida Beaches

Sat 9/20

3:15 pm-5:05 pm

Nonstop1h 50m

$187

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Tue 9/9

7:23 am-5:36 pm

2 stops10h 13m

Panama City NW Florida Beaches

Tue 9/16

3:29 pm-9:10 pm

1 stop5h 41m

$192

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 9/29

3:10 pm-4:55 pm

Nonstop1h 45m

Panama City NW Florida Beaches

Sat 10/4

5:05 pm-8:20 pm

1 stop3h 15m

$197

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Tue 10/21

5:15 pm-11:10 pm

1 stop5h 55m

Panama City NW Florida Beaches

Mon 10/27

6:17 pm-11:41 pm

1 stop5h 24m

$202

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Sat 9/6

9:17 am-8:16 pm

2 stops10h 59m

Panama City NW Florida Beaches

Wed 9/17

11:09 am-6:58 pm

1 stop7h 49m

$218

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 9/10

8:20 am-4:20 pm

1 stop8h 00m

Panama City NW Florida Beaches

Wed 9/17

11:09 am-11:44 pm

2 stops12h 35m

$274

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Missouri is in September. Flight prices, which tend to average around $361, are often lower during this time because this is during the off-season. The month of May is another great option to travel to Panama City, Florida, with average flight prices from Missouri averaging around $404.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $355. On the other hand, Friday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $524.

What is the cheapest Missouri to Panama City NW Florida Beaches flight route?

Fly from Kansas City to Panama City NW Florida Beaches for the best Missouri - Panama City NW Florida Beaches flight prices

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $415 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Missouri for as low as $292 on momondo.

What cabin class options are available on Missouri to Panama City NW Florida Beaches flights?

There are 1 cabin classes available to choose from on Missouri to Panama City NW Florida Beaches flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Panama City, Florida flights?

You could potentially save up to 50% on your flight if you consider stops on a Missouri to Panama City, Florida flight.

Cheap Missouri to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama City, Florida

Best Price Found

$79

Fastest flight time

1h 45m

Direct flights

Every day

Airports in Panama City, Florida

1 airport
The best one-way flight to Panama City, Florida from Missouri in the past 72 hours is $79. The best round-trip flight deal from Missouri to Panama City, Florida found on momondo in the last 72 hours is $157.
The fastest flight from Missouri to Panama City, Florida takes 1h 45m
Direct flights go from Missouri to Panama City, Florida every day.
There is 1 airport near Panama City, Florida: Panama City NW Florida Beaches (ECP)
Search flight deals

  • When did momondo last update prices for flights from Missouri to Panama City NW Florida Beaches Airport?

    Prices for flights from Missouri to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Missouri to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Missouri to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Missouri to Panama City, Florida?

Best airlines flying from Missouri to Panama City, Florida

Compare and see reviews for airlines that fly from Missouri to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $102Free CancellationRating
7.2
702 reviews
Search Allegiant Air flights
DeltaPriceFrom $216Free CancellationRating
8.0
7,979 reviews
Search Delta flights
American AirlinesPriceFrom $220Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $256Free CancellationRating
7.4
8,920 reviews
Search United Airlines flights
SouthwestPriceFrom $261Free CancellationRating
8.0
4,246 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama City?

It is quick and easy to find Missouri to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from Missouri to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Missouri. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Missouri to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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