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Cheap flights from Missouri to Panama City from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama City departing on 1/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Missouri to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:19 pm - 7:48 pm
MCI
-
ECP
6h 29m1 stop
Delta Logo
7:00 am - 12:10 pm
ECP
-
MCI
5h 10m1 stop
$237Delta
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
6:33 pm - 11:49 pm
MCI
-
ECP
5h 16m1 stop
American Airlines Logo
2:53 pm - 11:40 pm
ECP
-
MCI
8h 47m2 stops
$242American Airlines
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
5:52 am - 1:30 pm
MCI
-
ECP
7h 38m2 stops
American Airlines Logo
2:53 pm - 11:40 pm
ECP
-
MCI
8h 47m2 stops
$247American Airlines
Sat, Apr 25 - Wed, Apr 29
American Airlines Logo
5:47 am - 3:17 pm
MCI
-
ECP
9h 30m2 stops
American Airlines Logo
5:00 pm - 9:44 pm
ECP
-
MCI
4h 44m1 stop
$254American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
5:47 am - 3:17 pm
MCI
-
ECP
9h 30m2 stops
American Airlines Logo
5:00 pm - 9:44 pm
ECP
-
MCI
4h 44m1 stop
$255American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
6:44 am - 12:07 pm
MCI
-
ECP
5h 23m1 stop
American Airlines Logo
7:19 am - 4:45 pm
ECP
-
MCI
9h 26m2 stops
$261American Airlines
Mon, Feb 23 - Fri, Feb 27
Southwest Logo
6:50 am - 2:55 pm
MCI
-
ECP
8h 05m2 stops
Southwest Logo
5:25 am - 12:05 pm
ECP
-
MCI
6h 40m1 stop
$273Southwest
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
4:25 pm - 9:56 pm
MCI
-
ECP
5h 31m1 stop
United Airlines Logo
6:40 am - 11:49 am
ECP
-
MCI
5h 09m1 stop
$274United Airlines
Fri, Apr 3 - Sun, Apr 5
United Airlines Logo
5:45 am - 4:12 pm
MCI
-
ECP
10h 27m2 stops
United Airlines Logo
6:30 am - 8:33 pm
ECP
-
MCI
14h 03m2 stops
$278United Airlines
Tue, Jan 20 - Tue, Jan 27
Delta Logo
6:55 pm - 10:51 pm
STL
-
ECP
3h 56m1 stop
Delta Logo
6:00 am - 11:05 am
ECP
-
STL
5h 05m1 stop
$289Delta
Sun, Jan 11 - Sun, Jan 18

Delta flights from Missouri to Panama City, Florida

Our best Delta deals on Missouri to Panama City, Florida flight tickets
Delta
Apr 1
MCI1:19 pmKansas City
6h 29m
1 stop
ECP7:48 pmPanama City NW Florida Beaches
Apr 8
ECP7:00 amPanama City NW Florida Beaches
5h 10m
1 stop
MCI12:10 pmKansas City
$237
Find similar
Delta
Jan 11
STL6:55 pmLambert-St Louis
3h 56m
1 stop
ECP10:51 pmPanama City NW Florida Beaches
Jan 24
ECP7:20 amPanama City NW Florida Beaches
4h 34m
1 stop
STL11:54 amLambert-St Louis
$289
Find similar
Delta
Jan 10
MCI6:23 pmKansas City
4h 28m
1 stop
ECP10:51 pmPanama City NW Florida Beaches
Jan 17
ECP10:02 amPanama City NW Florida Beaches
4h 54m
1 stop
MCI2:56 pmKansas City
$294
Find similar

United Airlines flights from Missouri to Panama City, Florida

Our best United Airlines deals on Missouri to Panama City, Florida flight tickets
United Airlines
Jan 20
MCI5:45 amKansas City
10h 27m
2 stops
ECP4:12 pmPanama City NW Florida Beaches
Jan 27
ECP6:30 amPanama City NW Florida Beaches
14h 03m
2 stops
MCI8:33 pmKansas City
$278
Find similar
United Airlines
Jan 20
MCI8:05 amKansas City
8h 07m
1 stop
ECP4:12 pmPanama City NW Florida Beaches
Jan 22
ECP4:54 pmPanama City NW Florida Beaches
5h 46m
1 stop
MCI10:40 pmKansas City
$307
Find similar
United Airlines
Jan 20
MCI8:05 amKansas City
8h 07m
1 stop
ECP4:12 pmPanama City NW Florida Beaches
Jan 22
ECP6:30 amPanama City NW Florida Beaches
9h 38m
2 stops
MCI4:08 pmKansas City
$312
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Missouri to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Wed 4/1

1:19 pm-7:48 pm

1 stop6h 29m

Panama City NW Florida Beaches

Wed 4/8

7:00 am-12:10 pm

1 stop5h 10m

$237

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Wed 4/1

6:33 pm-11:49 pm

1 stop5h 16m

Panama City NW Florida Beaches

Wed 4/8

2:53 pm-11:40 pm

2 stops8h 47m

$242

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Sat 4/25

5:52 am-1:30 pm

2 stops7h 38m

Panama City NW Florida Beaches

Wed 4/29

2:53 pm-11:40 pm

2 stops8h 47m

$247

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Tue 4/21

5:47 am-3:17 pm

2 stops9h 30m

Panama City NW Florida Beaches

Tue 4/28

5:00 pm-9:44 pm

1 stop4h 44m

$254

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Tue 4/21

5:47 am-3:17 pm

2 stops9h 30m

Panama City NW Florida Beaches

Tue 4/28

5:00 pm-9:44 pm

1 stop4h 44m

$255

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Mon 2/23

6:44 am-12:07 pm

1 stop5h 23m

Panama City NW Florida Beaches

Fri 2/27

7:19 am-4:45 pm

2 stops9h 26m

$261

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Wed 3/4

6:50 am-2:55 pm

2 stops8h 05m

Panama City NW Florida Beaches

Sun 3/8

5:25 am-12:05 pm

1 stop6h 40m

$273

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Fri 4/3

4:25 pm-9:56 pm

1 stop5h 31m

Panama City NW Florida Beaches

Sun 4/5

6:40 am-11:49 am

1 stop5h 09m

$274

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Tue 1/20

5:45 am-4:12 pm

2 stops10h 27m

Panama City NW Florida Beaches

Tue 1/27

6:30 am-8:33 pm

2 stops14h 03m

$278

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Sun 1/11

6:55 pm-10:51 pm

1 stop3h 56m

Panama City NW Florida Beaches

Sun 1/18

6:00 am-11:05 am

1 stop5h 05m

$289

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Missouri to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Missouri is in October. Flight prices, which tend to average around $279, are often lower during this time because this is during the off-season. The month of December is another great option to travel to Panama City, Florida, with average flight prices from Missouri averaging around $302.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Wednesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $353. On the other hand, Saturday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $472.

What is the cheapest Missouri to Panama City NW Florida Beaches flight route?

Fly from Kansas City to Panama City NW Florida Beaches for the best Missouri - Panama City NW Florida Beaches flight prices

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $372 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Missouri for as low as $311 on momondo.

What cabin class options are available on Missouri to Panama City NW Florida Beaches flights?

There is only 1 cabin class available to choose from on Missouri to Panama City NW Florida Beaches flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Panama City, Florida flights?

You could potentially save up to 13% on your flight if you consider stops on a Missouri to Panama City, Florida flight.

Cheap Missouri to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama City, Florida

Fastest flight time

1h 45m

Direct flights

Mon, Tue, Wed, Fri and Sun

Airports in Panama City, Florida

1 airport
The fastest flight from Missouri to Panama City, Florida takes 1h 45m
Direct flights go from Missouri to Panama City, Florida on Monday, Tuesday, Wednesday, Friday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Panama City, Florida. From Missouri there are direct flights to Panama City NW Florida Beaches (ECP).
Search flight deals

  • When did momondo last update prices for flights from Missouri to Panama City NW Florida Beaches Airport?

    Prices for flights from Missouri to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Missouri to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Missouri to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Missouri to Panama City, Florida?

Best airlines flying from Missouri to Panama City, Florida

Compare and see reviews for airlines that fly from Missouri to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $176Free CancellationRating
7.9
8,005 reviews
Search Delta flights
American AirlinesPriceFrom $212Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
United AirlinesPriceFrom $226Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights
SouthwestPriceFrom $228Free CancellationRating
7.9
4,250 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama City?

It is quick and easy to find Missouri to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from Missouri to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Missouri. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Missouri to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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