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Cheap flights from Missouri to Greenville from $118

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Greenville departing on 9/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
7:35 am - 1:40 pmSTL  Lambert-St Louis-GSP Greenville
5h 05m1 stop Nashville Intl
Southwest Logo
6:55 pm - 10:10 pmGSP  Greenville-STL Lambert-St Louis
4h 15m1 stop Nashville Intl
$238Southwest
Sun, Sep 6 - Fri, Sep 11
Southwest Logo
7:35 am - 1:40 pmSTL  Lambert-St Louis-GSP Greenville
5h 05m1 stop Nashville Intl
Southwest Logo
4:40 pm - 10:10 pmGSP  Greenville-STL Lambert-St Louis
6h 30m2 stops Baltimore/Washington Nashville Intl
$243Southwest
Sun, Sep 6 - Fri, Sep 11
American Airlines Logo
6:53 am - 1:10 pmSTL  Lambert-St Louis-GSP Greenville
5h 17m1 stop Charlotte Douglas
American Airlines Logo
7:24 am - 1:16 pmGSP  Greenville-STL Lambert-St Louis
6h 52m1 stop Chicago O'Hare Intl
$255American Airlines
Thu, Sep 10 - Wed, Sep 16
American Airlines Logo
1:54 pm - 6:59 pmSTL  Lambert-St Louis-GSP Greenville
4h 05m1 stop Charlotte Douglas
American Airlines Logo
6:23 pm - 12:27 amGSP  Greenville-STL Lambert-St Louis
7h 04m1 stop Chicago O'Hare Intl
$255American Airlines
Thu, Sep 10 - Thu, Sep 17
United Airlines Logo
9:59 am - 7:00 pmMCI  Kansas City-GSP Greenville
8h 01m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
United Airlines Logo
5:46 pm - 10:00 pmGSP  Greenville-MCI Kansas City
5h 14m1 stop Chicago O'Hare Intl
$274United Airlines
Sat, Oct 3 - Mon, Oct 5
Delta Logo
5:35 pm - 10:51 pmSTL  Lambert-St Louis-GSP Greenville
4h 16m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:14 pm - 11:54 pmGSP  Greenville-STL Lambert-St Louis
5h 40m1 stop Atlanta Hartsfield-Jackson
$297Delta
Fri, Oct 9 - Mon, Oct 12
Delta Logo
5:35 pm - 9:51 pmSTL  Lambert-St Louis-GSP Greenville
3h 16m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:04 pm - 11:54 pmGSP  Greenville-STL Lambert-St Louis
5h 50m1 stop Atlanta Hartsfield-Jackson
$297Delta
Fri, Oct 9 - Mon, Oct 12
United Airlines Logo
11:22 am - 5:02 pmMCI  Kansas City-GSP Greenville
4h 40m1 stop Chicago O'Hare Intl
United Airlines Logo
3:01 pm - 7:32 pmGSP  Greenville-MCI Kansas City
5h 31m1 stop Washington, D.C. Dulles Intl
$317United Airlines
Mon, Aug 31 - Wed, Sep 2
Allegiant Air Logo
10:36 am - 2:25 pmMCI  Kansas City-GSP Greenville
26h 49m1 stop Tampa St. Petersburg
Allegiant Air Logo
1:29 pm - 8:26 amGSP  Greenville-MCI Kansas City
19h 57m1 stop Fort Lauderdale
$329Allegiant Air
Thu, Oct 15 - Sun, Oct 18
Multiple Airlines Logo
9:16 am - 6:30 pmMCI  Kansas City-GSP Greenville
8h 14m1 stop Fort Lauderdale
Multiple Airlines Logo
8:32 pm - 7:48 pmGSP  Greenville-MCI Kansas City
24h 16m2 stops Orlando Denver Intl
$348Multiple Airlines
Fri, Oct 9 - Mon, Oct 12

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Southwest flights from Missouri to Greenville

Our best Southwest deals on Missouri to Greenville flight tickets
Southwest
Sep 6
STL7:35 amLambert-St Louis
5h 05m
1 stop
GSP1:40 pmGreenville
Sep 11
GSP6:55 pmGreenville
4h 15m
1 stop
STL10:10 pmLambert-St Louis
$238
Southwest
Sep 6
STL7:35 amLambert-St Louis
5h 05m
1 stop
GSP1:40 pmGreenville
Sep 11
GSP4:40 pmGreenville
6h 30m
2 stops
STL10:10 pmLambert-St Louis
$243
Southwest
Sep 10
STL3:45 pmLambert-St Louis
4h 55m
1 stop
GSP9:40 pmGreenville
Sep 16
GSP5:30 pmGreenville
5h 45m
1 stop
STL10:15 pmLambert-St Louis
$256

American Airlines flights from Missouri to Greenville

Our best American Airlines deals on Missouri to Greenville flight tickets
American Airlines
Sep 10
STL1:54 pmLambert-St Louis
4h 05m
1 stop
GSP6:59 pmGreenville
Sep 17
GSP6:23 pmGreenville
7h 04m
1 stop
STL12:27 amLambert-St Louis
$255
American Airlines
Sep 5
MCI3:47 pmKansas City
7h 19m
1 stop
GSP12:06 amGreenville
Sep 11
GSP8:01 amGreenville
5h 22m
1 stop
MCI12:23 pmKansas City
$259
American Airlines
Sep 23
MCI2:14 pmKansas City
6h 40m
1 stop
GSP9:54 pmGreenville
Sep 30
GSP5:24 pmGreenville
7h 00m
1 stop
MCI11:24 pmKansas City
$269

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisGreenville

STL Lambert-St Louis - GSP Greenville

STLGSP

Lambert-St Louis

Sun 9/6

7:35 am-1:40 pm

1 stop5h 05m

Greenville

Fri 9/11

6:55 pm-10:10 pm

1 stop4h 15m

$238

St. LouisGreenville

STL Lambert-St Louis - GSP Greenville

STLGSP

Lambert-St Louis

Sun 9/6

7:35 am-1:40 pm

1 stop5h 05m

Greenville

Fri 9/11

4:40 pm-10:10 pm

2 stops6h 30m

$243

St. LouisGreenville

STL Lambert-St Louis - GSP Greenville

STLGSP

Lambert-St Louis

Thu 9/10

6:53 am-1:10 pm

1 stop5h 17m

Greenville

Wed 9/16

7:24 am-1:16 pm

1 stop6h 52m

$255

St. LouisGreenville

STL Lambert-St Louis - GSP Greenville

STLGSP

Lambert-St Louis

Thu 9/10

1:54 pm-6:59 pm

1 stop4h 05m

Greenville

Thu 9/17

6:23 pm-12:27 am

1 stop7h 04m

$255

Kansas CityGreenville

MCI Kansas City - GSP Greenville

MCIGSP

Kansas City

Sat 10/3

9:59 am-7:00 pm

2 stops8h 01m

Greenville

Mon 10/5

5:46 pm-10:00 pm

1 stop5h 14m

$274

St. LouisGreenville

STL Lambert-St Louis - GSP Greenville

STLGSP

Lambert-St Louis

Fri 10/9

5:35 pm-10:51 pm

1 stop4h 16m

Greenville

Mon 10/12

7:14 pm-11:54 pm

1 stop5h 40m

$297
Quickest round-trip

St. LouisGreenville

STL Lambert-St Louis - GSP Greenville

STLGSP

Lambert-St Louis

Fri 10/9

5:35 pm-9:51 pm

1 stop3h 16m

Greenville

Mon 10/12

7:04 pm-11:54 pm

1 stop5h 50m

$297

Kansas CityGreenville

MCI Kansas City - GSP Greenville

MCIGSP

Kansas City

Mon 8/31

11:22 am-5:02 pm

1 stop4h 40m

Greenville

Wed 9/2

3:01 pm-7:32 pm

1 stop5h 31m

$317

Kansas CityGreenville

MCI Kansas City - GSP Greenville

MCIGSP

Kansas City

Thu 10/15

10:36 am-2:25 pm

1 stop26h 49m

Greenville

Sun 10/18

1:29 pm-8:26 am

1 stop19h 57m

$329

Kansas CityGreenville

MCI Kansas City - GSP Greenville

MCIGSP

Kansas City

Fri 10/9

9:16 am-6:30 pm

1 stop8h 14m

Greenville

Mon 10/12

8:32 pm-7:48 pm

2 stops24h 16m

$348

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Missouri to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of February is another great option to travel to Greenville, with average flight prices from Missouri averaging around $376.

Cheap Missouri to Greenville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Greenville

Fastest flight time

3h 29m

Direct flights

None
The fastest flight from Missouri to Greenville takes 3h 29m
There are no direct flights from Missouri to Greenville. There are no popular flight routes from Missouri to Greenville.
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Frequently asked questions about flying from Missouri to Greenville

  • When did momondo last update prices for flights from Missouri to Greenville Airport?

    Prices for flights from Missouri to Greenville Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Missouri to Greenville Airport?

  • How old do you have to be to fly from Missouri to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Greenville

Compare and see reviews for airlines that fly from Missouri to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,950 reviews
Search American Airlines flights
DeltaPriceFrom $258Free CancellationRating
7.8
8,502 reviews
Search Delta flights
United AirlinesPriceFrom $287Free CancellationRating
7.4
10,104 reviews
Search United Airlines flights
SouthwestPriceFrom $291Free CancellationRating
8.0
4,217 reviews
Search Southwest flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Missouri to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Missouri to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Greenville?

momondo helps you find the best flight between Missouri and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Missouri to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

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