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Cheap flights from Missouri to Greenville from $128

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Greenville departing on 3/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Missouri to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:24 pm - 8:56 pm
MCI
-
GSP
7h 32m
1 stop
Multiple Airlines Logo
6:45 pm - 11:29 am
GSP
-
MCI
17h 44m
1 stop
$254Multiple Airlines
Thu, Mar 26 - Mon, Mar 30
Multiple Airlines Logo
12:24 pm - 8:56 pm
MCI
-
GSP
7h 32m
1 stop
Multiple Airlines Logo
6:45 pm - 11:29 am
GSP
-
MCI
17h 44m
1 stop
$258Multiple Airlines
Thu, Mar 26 - Mon, Mar 30
Southwest Logo
1:15 pm - 8:00 pm
STL
-
GSP
5h 45m
1 stop
Southwest Logo
5:10 pm - 7:20 pm
GSP
-
STL
3h 10m
1 stop
$292Southwest
Wed, Apr 15 - Wed, Apr 22
Delta Logo
7:10 am - 2:02 pm
STL
-
GSP
5h 52m
1 stop
Delta Logo
5:40 am - 11:09 am
GSP
-
STL
6h 29m
1 stop
$297Delta
Tue, Mar 3 - Tue, Mar 10
Southwest Logo
10:25 am - 8:00 pm
STL
-
GSP
8h 35m
2 stops
Southwest Logo
5:10 pm - 7:20 pm
GSP
-
STL
3h 10m
1 stop
$298Southwest
Wed, Apr 15 - Wed, Apr 22
American Airlines Logo
6:55 pm - 11:57 pm
STL
-
GSP
4h 02m
1 stop
American Airlines Logo
7:00 am - 11:37 am
GSP
-
STL
5h 37m
1 stop
$303American Airlines
Wed, Apr 15 - Wed, Apr 22
American Airlines Logo
2:33 pm - 10:40 pm
MCI
-
GSP
7h 07m
1 stop
American Airlines Logo
7:00 am - 2:48 pm
GSP
-
MCI
8h 48m
1 stop
$304American Airlines
Tue, Apr 7 - Thu, Apr 9
Delta Logo
5:13 pm - 11:56 pm
MCI
-
GSP
5h 43m
1 stop
Delta Logo
8:50 am - 1:58 pm
GSP
-
MCI
6h 08m
1 stop
$317Delta
Sat, May 2 - Tue, May 5
United Airlines Logo
3:13 pm - 8:51 pm
SGF
-
GSP
4h 38m
1 stop
United Airlines Logo
6:30 am - 10:39 am
GSP
-
SGF
5h 09m
1 stop
$457United Airlines
Sat, Mar 21 - Sun, Mar 29
United Airlines Logo
9:00 am - 3:36 pm
SGF
-
GSP
5h 36m
1 stop
United Airlines Logo
6:00 am - 8:21 pm
GSP
-
SGF
15h 21m
2 stops
$470United Airlines
Tue, Feb 24 - Sat, Feb 28

Southwest flights from Missouri to Greenville

Our best Southwest deals on Missouri to Greenville flight tickets
Southwest
Apr 15
STL2:30 pmLambert-St Louis
6h 10m
1 stop
GSP9:40 pmGreenville
Apr 22
GSP5:10 pmGreenville
3h 10m
1 stop
STL7:20 pmLambert-St Louis
$292
Southwest
Apr 15
STL12:40 pmLambert-St Louis
8h 00m
2 stops
GSP9:40 pmGreenville
Apr 22
GSP5:10 pmGreenville
3h 10m
1 stop
STL7:20 pmLambert-St Louis
$298
Southwest
Mar 24
STL6:00 pmLambert-St Louis
3h 40m
1 stop
GSP10:40 pmGreenville
Mar 31
GSP1:50 pmGreenville
7h 10m
2 stops
STL8:00 pmLambert-St Louis
$302

Delta flights from Missouri to Greenville

Our best Delta deals on Missouri to Greenville flight tickets
Delta
Mar 3
STL7:10 amLambert-St Louis
5h 52m
1 stop
GSP2:02 pmGreenville
Mar 10
GSP5:40 amGreenville
6h 29m
1 stop
STL11:09 amLambert-St Louis
$297
Delta
May 2
MCI5:13 pmKansas City
5h 43m
1 stop
GSP11:56 pmGreenville
May 5
GSP8:50 amGreenville
6h 08m
1 stop
MCI1:58 pmKansas City
$317
Delta
May 2
MCI7:00 amKansas City
4h 13m
1 stop
GSP12:13 pmGreenville
May 4
GSP7:59 pmGreenville
4h 51m
1 stop
MCI11:50 pmKansas City
$319

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Thu 3/26

12:24 pm-8:56 pm

1 stop7h 32m

Greenville

Mon 3/30

6:45 pm-11:29 am

1 stop17h 44m

$254

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Thu 3/26

12:24 pm-8:56 pm

1 stop7h 32m

Greenville

Mon 3/30

6:45 pm-11:29 am

1 stop17h 44m

$258

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 4/15

1:15 pm-8:00 pm

1 stop5h 45m

Greenville

Wed 4/22

5:10 pm-7:20 pm

1 stop3h 10m

$292

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 3/3

7:10 am-2:02 pm

1 stop5h 52m

Greenville

Tue 3/10

5:40 am-11:09 am

1 stop6h 29m

$297

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 4/15

10:25 am-8:00 pm

2 stops8h 35m

Greenville

Wed 4/22

5:10 pm-7:20 pm

1 stop3h 10m

$298

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 4/15

6:55 pm-11:57 pm

1 stop4h 02m

Greenville

Wed 4/22

7:00 am-11:37 am

1 stop5h 37m

$303

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Tue 4/7

2:33 pm-10:40 pm

1 stop7h 07m

Greenville

Thu 4/9

7:00 am-2:48 pm

1 stop8h 48m

$304

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Sat 5/2

5:13 pm-11:56 pm

1 stop5h 43m

Greenville

Tue 5/5

8:50 am-1:58 pm

1 stop6h 08m

$317

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Sat 3/21

3:13 pm-8:51 pm

1 stop4h 38m

Greenville

Sun 3/29

6:30 am-10:39 am

1 stop5h 09m

$457

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Tue 2/24

9:00 am-3:36 pm

1 stop5h 36m

Greenville

Sat 2/28

6:00 am-8:21 pm

2 stops15h 21m

$470

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Missouri to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of October is another great option to travel to Greenville, with average flight prices from Missouri averaging around $297.

Cheap Missouri to Greenville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Greenville

Fastest flight time

3h 51m

Direct flights

None
The fastest flight from Missouri to Greenville takes 3h 51m
There are no direct flights from Missouri to Greenville. There are no popular flight routes from Missouri to Greenville.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Greenville Airport?

    Prices for flights from Missouri to Greenville Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Missouri to Greenville Airport?

  • How old do you have to be to fly from Missouri to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Greenville

Compare and see reviews for airlines that fly from Missouri to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $216Free CancellationRating
7.9
8,174 reviews
Search Delta flights
American AirlinesPriceFrom $243Free CancellationRating
7.2
11,258 reviews
Search American Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Missouri to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Missouri to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Greenville?

momondo helps you find the best flight between Missouri and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Missouri to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

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