What is the cheapest airline that flies from Missouri to Greenville?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Missouri to Greenville

What airlines fly to Greenville?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Greenville from Missouri according to our data. American Airlines is the first choice among our users, with 73% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 6 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Greenville?

Flight times from Missouri to Greenville vary, but if you’re flying out of St. Louis and flying into Charlotte (one of the most popular routes), then the duration is 1h 45m on average. Another popular route from Missouri to Greenville is flying from Springfield to Charlotte, which will take roughly 2h 10m. Keep in mind that layovers or delays could extend your travel time.

When did momondo last update prices for flights from Missouri to Greenville Airport?

Prices for flights from Missouri to Greenville Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Missouri to Greenville Airport?

As of November 2025, there are 2 operators available to choose from for flights from Missouri to Greenville Airport.

How old do you have to be to fly from Missouri to Greenville Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$127 Cheap Flights from Missouri to Greenville in 2025/26

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Find the cheapest flights from Missouri to Greenville

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:47 pm - 2:10 pmSTL-GSP

22h 23m1 stop

8:03 pm - 10:33 pmGSP-STL

27h 30m1 stop

$232Multiple Airlines

Find Deal

Thu, Dec 4 - Mon, Dec 8

7:43 pm - 3:15 pmSTL-GSP

18h 32m2 stops

9:41 pm - 10:56 amGSP-STL

14h 15m1 stop

$255Multiple Airlines

Find Deal

Wed, Dec 17 - Sat, Dec 20

10:25 am - 7:23 pmSTL-GSP

7h 58m1 stop

3:56 pm - 11:57 pmGSP-STL

9h 01m1 stop

$262Multiple Airlines

Find Deal

Mon, Nov 17 - Thu, Nov 20

1:00 pm - 5:23 pmSGF-GSP

3h 23m1 stop

8:19 am - 11:20 amGSP-SGF

4h 01m1 stop

$274Delta

Find Deal

Sat, Feb 28 - Wed, Mar 4

1:00 pm - 6:49 pmSTL-GSP

4h 49m1 stop

6:45 am - 11:50 amGSP-STL

6h 05m1 stop

$281Delta

Find Deal

Tue, Apr 7 - Wed, Apr 8

8:20 pm - 8:49 pmSGF-GSP

23h 29m1 stop

9:39 pm - 5:09 pmGSP-SGF

20h 30m1 stop

$285Allegiant Air

Find Deal

Thu, Dec 4 - Mon, Dec 15

3:11 pm - 8:47 pmSTL-GSP

4h 36m1 stop

10:00 am - 5:43 pmGSP-STL

8h 43m2 stops

$286United Airlines

Find Deal

Mon, Jan 19 - Fri, Jan 23

12:55 pm - 7:10 pmSTL-GSP

5h 15m1 stop

5:28 pm - 9:40 pmGSP-STL

5h 12m1 stop

$297United Airlines

Find Deal

Tue, Dec 2 - Sat, Dec 6

6:05 am - 4:05 pmSTL-GSP

9h 00m2 stops

4:45 pm - 10:00 pmGSP-STL

6h 15m1 stop

$324Southwest

Find Deal

Thu, Dec 11 - Mon, Dec 15

6:05 am - 4:05 pmSTL-GSP

9h 00m2 stops

7:40 am - 1:50 pmGSP-STL

7h 10m2 stops

$329Southwest

Find Deal

Thu, Dec 11 - Mon, Dec 15

Delta flights from Missouri to Greenville

Our best Delta deals on Missouri to Greenville flight tickets

Delta

Feb 28

SGF1:00 pmSpringfield-Branson

3h 23m

1 stop

GSP5:23 pmGreenville

Mar 4

GSP8:19 amGreenville

4h 01m

1 stop

SGF11:20 amSpringfield-Branson

$274

Find similar

Delta

Apr 7

STL1:00 pmLambert-St Louis

4h 49m

1 stop

GSP6:49 pmGreenville

Apr 8

GSP6:45 amGreenville

6h 05m

1 stop

STL11:50 amLambert-St Louis

$281

Find similar

Delta

Jan 29

MCI1:22 pmKansas City

4h 17m

1 stop

GSP6:39 pmGreenville

Feb 2

GSP7:46 pmGreenville

5h 05m

1 stop

MCI11:51 pmKansas City

$301

Find similar

American Airlines flights from Missouri to Greenville

Our best American Airlines deals on Missouri to Greenville flight tickets

American Airlines

Nov 12

SGF5:35 pmSpringfield-Branson

4h 25m

1 stop

GSP11:00 pmGreenville

Nov 15

GSP12:47 pmGreenville

7h 14m

2 stops

SGF7:01 pmSpringfield-Branson

$344

Find similar

American Airlines

May 2

SGF4:32 pmSpringfield-Branson

5h 37m

1 stop

GSP11:09 pmGreenville

May 3

GSP7:25 amGreenville

4h 16m

1 stop

SGF10:41 amSpringfield-Branson

$355

Find similar

American Airlines

Dec 29

STL6:00 pmLambert-St Louis

5h 51m

1 stop

GSP12:51 amGreenville

Jan 4

GSP8:07 pmGreenville

6h 18m

1 stop

STL1:25 amLambert-St Louis

$367

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 12/4

2:47 pm-2:10 pm

1 stop22h 23m

Greenville

Mon 12/8

8:03 pm-10:33 pm

1 stop27h 30m

$232

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 12/17

7:43 pm-3:15 pm

2 stops18h 32m

Greenville

Sat 12/20

9:41 pm-10:56 am

1 stop14h 15m

$255

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 11/17

10:25 am-7:23 pm

1 stop7h 58m

Greenville

Thu 11/20

3:56 pm-11:57 pm

1 stop9h 01m

$262

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Sat 2/28

1:00 pm-5:23 pm

1 stop3h 23m

Greenville

Wed 3/4

8:19 am-11:20 am

1 stop4h 01m

$274

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 4/7

1:00 pm-6:49 pm

1 stop4h 49m

Greenville

Wed 4/8

6:45 am-11:50 am

1 stop6h 05m

$281

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Thu 12/4

8:20 pm-8:49 pm

1 stop23h 29m

Greenville

Mon 12/15

9:39 pm-5:09 pm

1 stop20h 30m

$285

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 1/19

3:11 pm-8:47 pm

1 stop4h 36m

Greenville

Fri 1/23

10:00 am-5:43 pm

2 stops8h 43m

$286

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 12/2

12:55 pm-7:10 pm

1 stop5h 15m

Greenville

Sat 12/6

5:28 pm-9:40 pm

1 stop5h 12m

$297

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 12/11

6:05 am-4:05 pm

2 stops9h 00m

Greenville

Mon 12/15

4:45 pm-10:00 pm

1 stop6h 15m

$324

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 12/11

6:05 am-4:05 pm

2 stops9h 00m

Greenville

Mon 12/15

7:40 am-1:50 pm

2 stops7h 10m

$329

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Greenville?

The month of October is another great option to travel to Greenville, with average flight prices from Missouri averaging around $297.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Missouri. The lowest ticket price found for a Wednesday departure recently was $322. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $537. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is at noon. Flights from Missouri to Greenville during this time can be as low as $326. Flights to Greenville are more costly in the afternoon, with an average ticket price of $401. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Missouri to Greenville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Greenville

Direct flights	None

There are no direct flights from Missouri to Greenville. There are no popular flight routes from Missouri to Greenville.

Search flight deals

When did momondo last update prices for flights from Missouri to Greenville Airport?
Prices for flights from Missouri to Greenville Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Missouri to Greenville Airport?
As of November 2025, there are 2 operators available to choose from for flights from Missouri to Greenville Airport.
How old do you have to be to fly from Missouri to Greenville Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Greenville

Compare and see reviews for airlines that fly from Missouri to Greenville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 8,001 reviews		Search Delta flights
American Airlines	PriceFrom $243	Free Cancellation	Rating 7.2 11,040 reviews		Search American Airlines flights

Anderson

Simpsonville

Greenwood

Seneca

Greer

Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Missouri to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Missouri to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Missouri to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from Missouri to Greenville?

momondo helps you find the best flight between Missouri and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Missouri to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.