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Cheap flights from Missouri to Chicago from $47

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Chicago departing on 7/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Contour Logo
9:55 am - 11:40 am
UIN
-
ORD
1h 45mnonstop
Contour Logo
12:30 pm - 1:55 pm
ORD
-
UIN
1h 25mnonstop
$102Contour
Thu, Sep 10 - Sun, Oct 11
Contour Logo
9:55 am - 11:30 am
UIN
-
ORD
1h 35mnonstop
Contour Logo
12:20 pm - 1:40 pm
ORD
-
UIN
1h 20mnonstop
$103Contour
Fri, Jul 10 - Tue, Jul 14
Southwest Logo
5:40 pm - 10:20 pm
STL
-
MDW
4h 40m
1 stop
Southwest Logo
6:20 am - 9:30 am
MDW
-
STL
3h 10m
1 stop
$215Southwest
Thu, Sep 17 - Mon, Sep 21
Delta Logo
1:55 pm - 8:30 pm
STL
-
ORD
6h 35m
1 stop
Delta Logo
1:55 pm - 8:35 pm
ORD
-
STL
6h 40m
1 stop
$215Delta
Mon, Sep 14 - Thu, Sep 24
Delta Logo
1:55 pm - 6:33 pm
STL
-
MDW
4h 38m
1 stop
Delta Logo
9:29 am - 3:14 pm
MDW
-
STL
5h 45m
1 stop
$218Delta
Mon, Sep 14 - Sat, Sep 19
Frontier Logo
10:35 am - 7:44 pm
STL
-
ORD
9h 09m
1 stop
Frontier Logo
2:03 pm - 9:40 am
ORD
-
STL
19h 37m
1 stop
$220Frontier
Mon, Sep 14 - Wed, Sep 23
American Airlines Logo
5:00 am - 6:24 am
STL
-
ORD
1h 24mnonstop
American Airlines Logo
11:00 pm - 12:14 am
ORD
-
STL
1h 14mnonstop
$225American Airlines
Sat, Aug 8 - Mon, Aug 10
Southwest Logo
5:40 am - 6:50 am
STL
-
MDW
1h 10mnonstop
Southwest Logo
7:45 am - 9:00 am
MDW
-
STL
1h 15mnonstop
$226Southwest
Mon, Oct 5 - Wed, Oct 7
Frontier Logo
7:03 pm - 5:37 am
STL
-
ORD
10h 34m
1 stop
Frontier Logo
7:05 am - 5:37 pm
ORD
-
STL
10h 32m
1 stop
$230Frontier
Tue, Jul 21 - Tue, Jul 28
American Airlines Logo
9:08 am - 10:36 am
STL
-
ORD
1h 28mnonstop
American Airlines Logo
7:04 am - 8:31 am
ORD
-
STL
1h 27mnonstop
$238American Airlines
Mon, Jul 20 - Wed, Jul 22

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American Airlines flights from Missouri to Chicago

Our best American Airlines deals on Missouri to Chicago flight tickets
American Airlines
Aug 8
STL5:00 amLambert-St Louis
1h 24m
ORD6:24 amChicago O'Hare Intl
Aug 10
ORD11:00 pmChicago O'Hare Intl
1h 14m
STL12:14 amLambert-St Louis
$225
American Airlines
Sep 27
STL5:18 pmLambert-St Louis
1h 55m
ORD7:13 pmChicago O'Hare Intl
Oct 3
ORD11:05 pmChicago O'Hare Intl
1h 22m
STL12:27 amLambert-St Louis
$227
American Airlines
Jul 20
STL9:08 amLambert-St Louis
1h 28m
ORD10:36 amChicago O'Hare Intl
Jul 22
ORD7:04 amChicago O'Hare Intl
1h 27m
STL8:31 amLambert-St Louis
$238

Contour flights from Missouri to Chicago

Our best Contour deals on Missouri to Chicago flight tickets
Contour
Jul 10
UIN9:55 amQuincy Regional
1h 35m
ORD11:30 amChicago O'Hare Intl
Jul 14
ORD12:20 pmChicago O'Hare Intl
1h 20m
UIN1:40 pmQuincy Regional
$103
Contour
Jul 8
UIN9:55 amQuincy Regional
1h 35m
ORD11:30 amChicago O'Hare Intl
Jul 23
ORD12:20 pmChicago O'Hare Intl
1h 20m
UIN1:40 pmQuincy Regional
$104
Contour
Sep 30
UIN9:55 amQuincy Regional
1h 45m
ORD11:40 amChicago O'Hare Intl
Oct 3
ORD12:30 pmChicago O'Hare Intl
1h 25m
UIN1:55 pmQuincy Regional
$118

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Missouri to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Thu 9/10

9:55 am-11:40 am

Nonstop1h 45m

Chicago O'Hare Intl

Sun 10/11

12:30 pm-1:55 pm

Nonstop1h 25m

$102

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Fri 7/10

9:55 am-11:30 am

Nonstop1h 35m

Chicago O'Hare Intl

Tue 7/14

12:20 pm-1:40 pm

Nonstop1h 20m

$103

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Thu 9/17

5:40 pm-10:20 pm

1 stop4h 40m

Chicago Midway

Mon 9/21

6:20 am-9:30 am

1 stop3h 10m

$215

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Mon 9/14

1:55 pm-8:30 pm

1 stop6h 35m

Chicago O'Hare Intl

Thu 9/24

1:55 pm-8:35 pm

1 stop6h 40m

$215

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Mon 9/14

1:55 pm-6:33 pm

1 stop4h 38m

Chicago Midway

Sat 9/19

9:29 am-3:14 pm

1 stop5h 45m

$218

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Mon 9/14

10:35 am-7:44 pm

1 stop9h 09m

Chicago O'Hare Intl

Wed 9/23

2:03 pm-9:40 am

1 stop19h 37m

$220

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Sat 8/8

5:00 am-6:24 am

Nonstop1h 24m

Chicago O'Hare Intl

Mon 8/10

11:00 pm-12:14 am

Nonstop1h 14m

$225
Quickest round-trip

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Mon 10/5

5:40 am-6:50 am

Nonstop1h 10m

Chicago Midway

Wed 10/7

7:45 am-9:00 am

Nonstop1h 15m

$226

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 7/21

7:03 pm-5:37 am

1 stop10h 34m

Chicago O'Hare Intl

Tue 7/28

7:05 am-5:37 pm

1 stop10h 32m

$230

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Mon 7/20

9:08 am-10:36 am

Nonstop1h 28m

Chicago O'Hare Intl

Wed 7/22

7:04 am-8:31 am

Nonstop1h 27m

$238

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Missouri to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of August is, on average, the cheapest month to fly to Chicago from Missouri, with most prices found around $61. If you’re not able to fly to Chicago in August, then September is your next best option. Flight prices from Missouri to Chicago during September average around $62.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $600. This is often the case because there is less demand to fly during this day of the week. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Missouri to Chicago for around $790.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Missouri to Chicago during this time can be as low as $575. In contrast, the most expensive time of day to depart to Chicago is at noon when prices are around $1,120.

What is the cheapest Missouri to Chicago flight route?

Fly from Kirksville Cannon Memorial to Chicago O'Hare Intl for the best Missouri - Chicago flight prices

How far in advance should I book a flight from Missouri to Chicago?

You are more likely to see cheaper flights to Chicago from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $322 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Missouri for as low as $97 on momondo.

What cabin class options are available on Missouri to Chicago flights?

There are 4 cabin classes available to choose from on Missouri to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Chicago flights?

No. A direct flight is the cheapest option for a flight between Missouri to Chicago.

Cheap Missouri to Chicago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Chicago

Best Price Found

$181

Fastest flight time

1h 05m

Direct flights

Every day

Airports in Chicago

3 airports
The best one-way flight to Chicago from Missouri in the past 72 hours is $181. The best round-trip flight deal from Missouri to Chicago found on momondo in the last 72 hours is $232.
The fastest flight from Missouri to Chicago takes 1h 05m
Direct flights go from Missouri to Chicago every day.
There are 3 airports in Chicago. From Missouri there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).
Search flight deals

Frequently asked questions about flying from Missouri to Chicago

  • When did momondo last update prices for flights from Missouri to Chicago?

    Prices for flights from Missouri to Chicago are refreshed on a daily basis.

  • How many operators does momondo search for flights from Missouri to Chicago?

  • How old do you have to be to fly from Missouri to Chicago?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Missouri to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Missouri to Chicago?

Best airlines flying from Missouri to Chicago

Compare and see reviews for airlines that fly from Missouri to Chicago with momondo
Airline
Rating
Free Cancellation
Price
ContourPriceFrom $62Free CancellationRating
7.7
42 reviews
Search Contour flights
American AirlinesPriceFrom $97Free CancellationRating
7.1
11,779 reviews
Search American Airlines flights
United AirlinesPriceFrom $128Free CancellationRating
7.4
9,901 reviews
Search United Airlines flights
SouthwestPriceFrom $137Free CancellationRating
7.9
4,246 reviews
Search Southwest flights
FrontierPriceFrom $158Free CancellationRating
5.6
2,858 reviews
Search Frontier flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Portage
Benton Harbor
Saint Joseph
Lansing
Valparaiso
Schererville
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Chicago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Missouri to Chicago for you.

Can I find flights from Missouri to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Missouri which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Missouri to Chicago?

Once all potential Missouri to Chicago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport