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Cheap flights from Missouri to Charleston from $78

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Charleston departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:22 pm - 5:36 pm
STL
-
CHS
20h 14m2 stops
Multiple Airlines Logo
3:01 pm - 10:27 pm
CHS
-
STL
8h 26m1 stop
$165Multiple Airlines
Wed, Feb 4 - Tue, Feb 10
Spirit Airlines Logo
11:26 am - 5:36 pm
MCI
-
CHS
29h 10m1 stop
Spirit Airlines Logo
6:35 pm - 10:31 am
CHS
-
MCI
16h 56m1 stop
$177Spirit Airlines
Thu, Jan 29 - Sun, Feb 1
Multiple Airlines Logo
5:04 pm - 8:38 am
MCI
-
CHS
14h 34m1 stop
Multiple Airlines Logo
6:35 pm - 10:31 am
CHS
-
MCI
16h 56m1 stop
$201Multiple Airlines
Mon, Feb 2 - Fri, Feb 6
Multiple Airlines Logo
3:49 pm - 3:55 pm
STL
-
CHS
23h 06m2 stops
Multiple Airlines Logo
3:21 pm - 12:27 am
CHS
-
STL
10h 06m1 stop
$205Multiple Airlines
Tue, Feb 17 - Fri, Feb 20
Spirit Airlines Logo
11:26 am - 4:10 pm
MCI
-
CHS
27h 44m2 stops
Spirit Airlines Logo
6:35 pm - 10:31 am
CHS
-
MCI
16h 56m1 stop
$215Spirit Airlines
Thu, Jan 29 - Sun, Feb 1
Multiple Airlines Logo
10:06 am - 5:36 pm
STL
-
CHS
30h 30m2 stops
Multiple Airlines Logo
3:01 pm - 11:33 pm
CHS
-
STL
9h 32m1 stop
$222Multiple Airlines
Sun, Jan 18 - Thu, Jan 22
United Airlines Logo
3:10 pm - 9:27 pm
COU
-
CHS
5h 17m1 stop
United Airlines Logo
8:15 am - 2:11 pm
CHS
-
COU
6h 56m1 stop
$258United Airlines
Mon, Mar 2 - Mon, Mar 9
United Airlines Logo
11:15 am - 11:44 pm
COU
-
CHS
11h 29m2 stops
United Airlines Logo
4:55 pm - 9:33 pm
CHS
-
COU
5h 38m1 stop
$264United Airlines
Mon, Mar 2 - Mon, Mar 9
American Airlines Logo
6:37 pm - 11:29 pm
SGF
-
CHS
3h 52m1 stop
American Airlines Logo
5:32 am - 10:19 am
CHS
-
SGF
5h 47m1 stop
$294American Airlines
Tue, Jun 2 - Wed, Jun 10
American Airlines Logo
1:13 pm - 11:04 pm
SGF
-
CHS
8h 51m2 stops
American Airlines Logo
12:29 pm - 8:25 pm
CHS
-
SGF
8h 56m2 stops
$304American Airlines
Sat, Jan 10 - Fri, Jan 16

United Airlines flights from Missouri to Charleston

Our best United Airlines deals on Missouri to Charleston flight tickets
United Airlines
Mar 2
COU3:10 pmColumbia Regional
5h 17m
1 stop
CHS9:27 pmCharleston
Mar 9
CHS8:15 amCharleston
6h 56m
1 stop
COU2:11 pmColumbia Regional
$258
Find similar
United Airlines
Mar 2
COU11:15 amColumbia Regional
11h 29m
2 stops
CHS11:44 pmCharleston
Mar 9
CHS4:55 pmCharleston
5h 38m
1 stop
COU9:33 pmColumbia Regional
$264
Find similar
United Airlines
Jan 10
SGF7:45 amSpringfield-Branson
5h 17m
1 stop
CHS2:02 pmCharleston
Jan 16
CHS4:41 pmCharleston
6h 17m
1 stop
SGF9:58 pmSpringfield-Branson
$269
Find similar

Southwest flights from Missouri to Charleston

Our best Southwest deals on Missouri to Charleston flight tickets
Southwest
Feb 4
STL10:15 amLambert-St Louis
6h 20m
2 stops
CHS5:35 pmCharleston
Feb 10
CHS7:55 amCharleston
8h 05m
2 stops
STL3:00 pmLambert-St Louis
$323
Find similar
Southwest
Feb 26
STL10:35 amLambert-St Louis
11h 40m
2 stops
CHS11:15 pmCharleston
Mar 2
CHS4:10 pmCharleston
8h 25m
1 stop
STL11:35 pmLambert-St Louis
$342
Find similar
Southwest
Feb 26
STL10:35 amLambert-St Louis
11h 40m
2 stops
CHS11:15 pmCharleston
Mar 2
CHS7:35 amCharleston
7h 35m
2 stops
STL2:10 pmLambert-St Louis
$347
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Wed 2/4

8:22 pm-5:36 pm

2 stops20h 14m

Charleston

Tue 2/10

3:01 pm-10:27 pm

1 stop8h 26m

$165

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Thu 1/29

11:26 am-5:36 pm

1 stop29h 10m

Charleston

Sun 2/1

6:35 pm-10:31 am

1 stop16h 56m

$177

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Mon 2/2

5:04 pm-8:38 am

1 stop14h 34m

Charleston

Fri 2/6

6:35 pm-10:31 am

1 stop16h 56m

$201

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Tue 2/17

3:49 pm-3:55 pm

2 stops23h 06m

Charleston

Fri 2/20

3:21 pm-12:27 am

1 stop10h 06m

$205

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Thu 1/29

11:26 am-4:10 pm

2 stops27h 44m

Charleston

Sun 2/1

6:35 pm-10:31 am

1 stop16h 56m

$215

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sun 1/18

10:06 am-5:36 pm

2 stops30h 30m

Charleston

Thu 1/22

3:01 pm-11:33 pm

1 stop9h 32m

$222

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Mon 3/2

3:10 pm-9:27 pm

1 stop5h 17m

Charleston

Mon 3/9

8:15 am-2:11 pm

1 stop6h 56m

$258

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Mon 3/2

11:15 am-11:44 pm

2 stops11h 29m

Charleston

Mon 3/9

4:55 pm-9:33 pm

1 stop5h 38m

$264

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

Tue 6/2

6:37 pm-11:29 pm

1 stop3h 52m

Charleston

Wed 6/10

5:32 am-10:19 am

1 stop5h 47m

$294

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

Sat 1/10

1:13 pm-11:04 pm

2 stops8h 51m

Charleston

Fri 1/16

12:29 pm-8:25 pm

2 stops8h 56m

$304

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Missouri to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Missouri is in August. Flight prices, which tend to average around $319, are often lower during this time because this is during the off-season. The month of November is another great option to travel to Charleston, with average flight prices from Missouri averaging around $328.

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Missouri to Charleston is on a Monday. Travelers who choose to depart for Charleston on a Monday will often find tickets for as low as $353. The most expensive day to fly to Charleston is Thursday, with ticket prices averaging around $488.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the evening when flights can be purchased for as low as $387. In the afternoon is when there is more demand to fly to Charleston, so prices are often more expensive at around $456 per ticket.

What is the cheapest Missouri to Charleston flight route?

Fly from Lambert-St Louis to Charleston for the best Missouri - Charleston flight prices

How far in advance should I book a flight to Charleston?

You are more likely to see cheaper flights to Charleston from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Charleston for around $388 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charleston from Missouri for as low as $336 on momondo.

What cabin class options are available on Missouri to Charleston flights?

There is only 1 cabin class available to choose from on Missouri to Charleston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Charleston flights?

No. A direct flight is the cheapest option for a flight between Missouri to Charleston.

Cheap Missouri to Charleston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Charleston

Fastest flight time

1h 55m

Direct flights

Mon, Sat and Sun

Airports in Charleston

1 airport
The fastest flight from Missouri to Charleston takes 1h 55m
Direct flights go from Missouri to Charleston on Monday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Charleston. From Missouri there are direct flights to Charleston (CHS).
Search flight deals

  • When did momondo last update prices for flights from Missouri to Charleston Airport?

    Prices for flights from Missouri to Charleston Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Missouri to Charleston Airport?

  • How old do you have to be to fly from Missouri to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents you'll need for your trip to Charleston Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Charleston Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Missouri to Charleston?

Best airlines flying from Missouri to Charleston

Compare and see reviews for airlines that fly from Missouri to Charleston with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $206Free CancellationRating
7.9
8,014 reviews
Search Delta flights
SouthwestPriceFrom $237Free CancellationRating
8.0
4,253 reviews
Search Southwest flights
American AirlinesPriceFrom $246Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Summerville
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Charleston?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Charleston from Missouri.

Can I find flights from Missouri to Charleston with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Charleston from Missouri with this policy.

How can momondo help me find flights from Missouri to Charleston?

Once you have performed a search for Missouri to Charleston flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Missouri to Charleston right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Missouri to Charleston now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Charleston and let you know when they change.

An easier way to manage your Charleston trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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