Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Missouri to Charleston from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Charleston departing on 7/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Missouri to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:20 pm - 8:15 pm
STL
-
CHS
1h 55mnonstop
Southwest Logo
3:40 pm - 5:00 pm
CHS
-
STL
2h 20mnonstop
$238Southwest
Sat, May 30 - Wed, Jun 3
Southwest Logo
5:20 pm - 8:15 pm
STL
-
CHS
1h 55mnonstop
Southwest Logo
4:45 pm - 5:50 pm
CHS
-
STL
2h 05mnonstop
$239Southwest
Sat, May 30 - Thu, Jun 4
American Airlines Logo
7:03 am - 2:53 pm
STL
-
CHS
6h 50m
1 stop
American Airlines Logo
7:10 pm - 11:59 pm
CHS
-
STL
5h 49m
1 stop
$259American Airlines
Mon, Jun 1 - Sat, Jun 6
Delta Logo
6:57 pm - 12:36 am
SGF
-
CHS
4h 39m
1 stop
Delta Logo
11:05 am - 3:20 pm
CHS
-
SGF
5h 15m
1 stop
$307Delta
Fri, Jun 26 - Sat, Jul 4
United Airlines Logo
3:25 pm - 9:51 pm
COU
-
CHS
5h 26m
1 stop
United Airlines Logo
7:00 pm - 11:33 pm
CHS
-
COU
5h 33m
1 stop
$308United Airlines
Sat, Jun 6 - Fri, Jun 12
Multiple Airlines Logo
6:24 pm - 7:58 pm
MCI
-
CHS
24h 34m
2 stops
Multiple Airlines Logo
8:20 pm - 9:50 am
CHS
-
MCI
14h 30m
1 stop
$308Multiple Airlines
Fri, Jun 5 - Thu, Jun 11
Multiple Airlines Logo
6:24 pm - 10:47 pm
MCI
-
CHS
27h 23m
2 stops
Multiple Airlines Logo
8:20 pm - 9:50 am
CHS
-
MCI
14h 30m
1 stop
$326Multiple Airlines
Mon, Jun 8 - Thu, Jun 11
Delta Logo
3:20 pm - 10:07 pm
SGF
-
CHS
5h 47m
1 stop
Delta Logo
6:45 pm - 10:21 pm
CHS
-
SGF
4h 36m
1 stop
$327Delta
Thu, Aug 27 - Sun, Aug 30
American Airlines Logo
10:30 am - 7:21 pm
COU
-
CHS
7h 51m
1 stop
American Airlines Logo
3:43 pm - 10:25 pm
CHS
-
COU
7h 42m
1 stop
$328American Airlines
Sat, May 23 - Wed, May 27
United Airlines Logo
10:53 am - 11:56 pm
COU
-
CHS
12h 03m
2 stops
United Airlines Logo
6:00 am - 10:18 am
CHS
-
COU
5h 18m
1 stop
$334United Airlines
Sat, May 23 - Wed, May 27

Southwest flights from Missouri to Charleston

Our best Southwest deals on Missouri to Charleston flight tickets
Southwest
Jun 17
STL3:15 pmLambert-St Louis
2h 00m
CHS6:15 pmCharleston
Jul 15
CHS1:50 pmCharleston
2h 10m
STL3:00 pmLambert-St Louis
$237
Southwest
May 30
STL5:20 pmLambert-St Louis
1h 55m
CHS8:15 pmCharleston
Jun 3
CHS3:40 pmCharleston
2h 20m
STL5:00 pmLambert-St Louis
$238
Southwest
May 30
STL5:20 pmLambert-St Louis
1h 55m
CHS8:15 pmCharleston
Jun 4
CHS4:45 pmCharleston
2h 05m
STL5:50 pmLambert-St Louis
$239

United Airlines flights from Missouri to Charleston

Our best United Airlines deals on Missouri to Charleston flight tickets
United Airlines
Jun 6
COU3:25 pmColumbia Regional
5h 26m
1 stop
CHS9:51 pmCharleston
Jun 12
CHS7:00 pmCharleston
5h 33m
1 stop
COU11:33 pmColumbia Regional
$308
United Airlines
May 23
COU10:53 amColumbia Regional
12h 03m
2 stops
CHS11:56 pmCharleston
May 27
CHS6:00 amCharleston
5h 18m
1 stop
COU10:18 amColumbia Regional
$334
United Airlines
May 23
COU10:53 amColumbia Regional
12h 03m
2 stops
CHS11:56 pmCharleston
May 27
CHS2:47 pmCharleston
8h 12m
2 stops
COU9:59 pmColumbia Regional
$339

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sat 5/30

5:20 pm-8:15 pm

Nonstop1h 55m

Charleston

Wed 6/3

3:40 pm-5:00 pm

Nonstop2h 20m

$238
Quickest round-trip

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sat 5/30

5:20 pm-8:15 pm

Nonstop1h 55m

Charleston

Thu 6/4

4:45 pm-5:50 pm

Nonstop2h 05m

$239

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 6/1

7:03 am-2:53 pm

1 stop6h 50m

Charleston

Sat 6/6

7:10 pm-11:59 pm

1 stop5h 49m

$259

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

Fri 6/26

6:57 pm-12:36 am

1 stop4h 39m

Charleston

Sat 7/4

11:05 am-3:20 pm

1 stop5h 15m

$307

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 6/6

3:25 pm-9:51 pm

1 stop5h 26m

Charleston

Fri 6/12

7:00 pm-11:33 pm

1 stop5h 33m

$308

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Fri 6/5

6:24 pm-7:58 pm

2 stops24h 34m

Charleston

Thu 6/11

8:20 pm-9:50 am

1 stop14h 30m

$308

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Mon 6/8

6:24 pm-10:47 pm

2 stops27h 23m

Charleston

Thu 6/11

8:20 pm-9:50 am

1 stop14h 30m

$326

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

Thu 8/27

3:20 pm-10:07 pm

1 stop5h 47m

Charleston

Sun 8/30

6:45 pm-10:21 pm

1 stop4h 36m

$327

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 5/23

10:30 am-7:21 pm

1 stop7h 51m

Charleston

Wed 5/27

3:43 pm-10:25 pm

1 stop7h 42m

$328

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Sat 5/23

10:53 am-11:56 pm

2 stops12h 03m

Charleston

Wed 5/27

6:00 am-10:18 am

1 stop5h 18m

$334

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Charleston from

How to get the cheapest flight ticket from Missouri to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Missouri is in June. Flight prices, which tend to average around $109, are often lower during this time because this is during the off-season. The month of April is another great option to travel to Charleston, with average flight prices from Missouri averaging around $181.

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Missouri to Charleston is on a Tuesday. Travelers who choose to depart for Charleston on a Tuesday will often find tickets for as low as $308. The most expensive day to fly to Charleston is Thursday, with ticket prices averaging around $530.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the afternoon when flights can be purchased for as low as $364. At noon is when there is more demand to fly to Charleston, so prices are often more expensive at around $461 per ticket.

What is the cheapest Missouri to Charleston flight route?

Fly from Lambert-St Louis to Charleston for the best Missouri - Charleston flight prices

How far in advance should I book a flight from Missouri to Charleston?

You are more likely to see cheaper flights to Charleston from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Charleston for around $373 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charleston from Missouri for as low as $315 on momondo.

Can stopping save me money on Missouri to Charleston flights?

You could potentially save up to 28% on your flight if you consider stops on a Missouri to Charleston flight.

Cheap Missouri to Charleston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Charleston

Best Price Found

$365

Fastest flight time

1h 55m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun

Airports in Charleston

1 airport
The best flight deal from Missouri to Charleston found on momondo in the last 72 hours is $365
The fastest flight from Missouri to Charleston takes 1h 55m
Direct flights go from Missouri to Charleston on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Charleston. From Missouri there are direct flights to Charleston (CHS).
Search flight deals

Frequently asked questions about flying from Missouri to Charleston

  • When did momondo last update prices for flights from Missouri to Charleston Airport?

    Prices for flights from Missouri to Charleston Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Missouri to Charleston Airport?

  • How old do you have to be to fly from Missouri to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents you'll need for your trip to Charleston Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Charleston Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Missouri to Charleston?

Best airlines flying from Missouri to Charleston

Compare and see reviews for airlines that fly from Missouri to Charleston with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $206Free CancellationRating
7.9
8,451 reviews
Search Delta flights
SouthwestPriceFrom $237Free CancellationRating
8.0
4,298 reviews
Search Southwest flights
American AirlinesPriceFrom $243Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights
United AirlinesPriceFrom $283Free CancellationRating
7.4
9,699 reviews
Search United Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Summerville
Kiawah Island
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Seabrook Island
Edisto Beach

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Charleston?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Charleston from Missouri.

Can I find flights from Missouri to Charleston with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Charleston from Missouri with this policy.

How can momondo help me find flights from Missouri to Charleston?

Once you have performed a search for Missouri to Charleston flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Missouri to Charleston right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Missouri to Charleston now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Charleston and let you know when they change.

An easier way to manage your Charleston trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 6/10
Wed 6/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States