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Cheap flights from Mississippi to Key West from $222

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Key West departing on 10/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Mississippi to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:58 pm - 9:02 amMEM  Memphis-EYW Key West
12h 04m1 stop Tampa
Multiple Airlines Logo
9:12 am - 2:20 pmEYW  Key West-MEM Memphis
6h 08m1 stop Tampa St. Petersburg
$222Multiple Airlines
Fri, Oct 30 - Sun, Nov 1
Multiple Airlines Logo
7:58 pm - 9:24 amMEM  Memphis-EYW Key West
12h 26m1 stop Tampa
Multiple Airlines Logo
8:54 pm - 7:05 amEYW  Key West-MEM Memphis
11h 11m1 stop Orlando Sanford Intl
$227Multiple Airlines
Fri, Oct 30 - Thu, Nov 5
Allegiant Air Logo
3:05 pm - 1:13 pmMEM  Memphis-EYW Key West
21h 08m1 stop Tampa St. Petersburg
Allegiant Air Logo
9:12 am - 2:20 pmEYW  Key West-MEM Memphis
6h 08m1 stop Tampa St. Petersburg
$229Allegiant Air
Thu, Oct 29 - Sun, Nov 1
Allegiant Air Logo
3:05 pm - 1:13 pmMEM  Memphis-EYW Key West
21h 08m1 stop Tampa St. Petersburg
Allegiant Air Logo
8:54 pm - 7:05 amEYW  Key West-MEM Memphis
11h 11m1 stop Orlando Sanford Intl
$235Allegiant Air
Thu, Oct 29 - Thu, Nov 5
Delta Logo
6:00 am - 10:46 amMEM  Memphis-EYW Key West
3h 46m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:40 am - 10:47 amEYW  Key West-MEM Memphis
4h 07m1 stop Atlanta Hartsfield-Jackson
$309Delta
Sat, Sep 12 - Sat, Sep 19
Delta Logo
11:55 am - 8:01 pmMEM  Memphis-EYW Key West
7h 06m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:40 am - 12:53 pmEYW  Key West-MEM Memphis
6h 13m1 stop Atlanta Hartsfield-Jackson
$309Delta
Sat, Oct 17 - Wed, Oct 21
Delta Logo
1:38 pm - 8:01 pmMEM  Memphis-EYW Key West
5h 23m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:40 am - 12:53 pmEYW  Key West-MEM Memphis
6h 13m1 stop Atlanta Hartsfield-Jackson
$309Delta
Wed, Oct 28 - Wed, Nov 4
American Airlines Logo
3:42 pm - 9:47 pmJAN  Jackson-Evers Intl-EYW Key West
5h 05m1 stop Charlotte Douglas
American Airlines Logo
6:43 pm - 11:30 pmEYW  Key West-JAN Jackson-Evers Intl
5h 47m1 stop Charlotte Douglas
$319American Airlines
Tue, Jan 26 - Sat, Jan 30
American Airlines Logo
12:50 pm - 9:47 pmJAN  Jackson-Evers Intl-EYW Key West
7h 57m1 stop Charlotte Douglas
American Airlines Logo
6:43 pm - 11:30 pmEYW  Key West-JAN Jackson-Evers Intl
5h 47m1 stop Charlotte Douglas
$319American Airlines
Sat, Jan 30 - Wed, Feb 3
American Airlines Logo
7:05 am - 12:43 pmMEM  Memphis-EYW Key West
4h 38m1 stop Charlotte Douglas
American Airlines Logo
8:03 pm - 11:49 pmEYW  Key West-MEM Memphis
4h 46m1 stop Miami
$361American Airlines
Tue, Dec 22 - Tue, Dec 29

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Delta flights from Mississippi to Key West

Our best Delta deals on Mississippi to Key West flight tickets
Delta
Oct 17
MEM11:55 amMemphis
7h 06m
1 stop
EYW8:01 pmKey West
Oct 21
EYW7:40 amKey West
6h 13m
1 stop
MEM12:53 pmMemphis
$309
Delta
Sep 1
MOB6:00 amMobile
6h 00m
1 stop
EYW1:00 pmKey West
Sep 5
EYW7:40 amKey West
4h 40m
1 stop
MOB11:20 amMobile
$319
Delta
Sep 19
MOB12:10 pmMobile
6h 50m
1 stop
EYW8:00 pmKey West
Sep 22
EYW6:19 pmKey West
6h 01m
1 stop
MOB11:20 pmMobile
$334

American Airlines flights from Mississippi to Key West

Our best American Airlines deals on Mississippi to Key West flight tickets
American Airlines
Jan 26
JAN3:42 pmJackson-Evers Intl
5h 05m
1 stop
EYW9:47 pmKey West
Jan 30
EYW6:43 pmKey West
5h 47m
1 stop
JAN11:30 pmJackson-Evers Intl
$319
American Airlines
Dec 22
MEM7:05 amMemphis
4h 38m
1 stop
EYW12:43 pmKey West
Dec 29
EYW8:03 pmKey West
4h 46m
1 stop
MEM11:49 pmMemphis
$361
American Airlines
Dec 22
MEM7:05 amMemphis
11h 16m
2 stops
EYW7:21 pmKey West
Dec 29
EYW8:03 pmKey West
4h 46m
1 stop
MEM11:49 pmMemphis
$393

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Mississippi to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisKey West

MEM Memphis - EYW Key West

MEMEYW

Memphis

Fri 10/30

7:58 pm-9:02 am

1 stop12h 04m

Key West

Sun 11/1

9:12 am-2:20 pm

1 stop6h 08m

$222

MemphisKey West

MEM Memphis - EYW Key West

MEMEYW

Memphis

Fri 10/30

7:58 pm-9:24 am

1 stop12h 26m

Key West

Thu 11/5

8:54 pm-7:05 am

1 stop11h 11m

$227

MemphisKey West

MEM Memphis - EYW Key West

MEMEYW

Memphis

Thu 10/29

3:05 pm-1:13 pm

1 stop21h 08m

Key West

Sun 11/1

9:12 am-2:20 pm

1 stop6h 08m

$229

MemphisKey West

MEM Memphis - EYW Key West

MEMEYW

Memphis

Thu 10/29

3:05 pm-1:13 pm

1 stop21h 08m

Key West

Thu 11/5

8:54 pm-7:05 am

1 stop11h 11m

$235
Quickest round-trip

MemphisKey West

MEM Memphis - EYW Key West

MEMEYW

Memphis

Sat 9/12

6:00 am-10:46 am

1 stop3h 46m

Key West

Sat 9/19

7:40 am-10:47 am

1 stop4h 07m

$309

MemphisKey West

MEM Memphis - EYW Key West

MEMEYW

Memphis

Sat 10/17

11:55 am-8:01 pm

1 stop7h 06m

Key West

Wed 10/21

7:40 am-12:53 pm

1 stop6h 13m

$309

MemphisKey West

MEM Memphis - EYW Key West

MEMEYW

Memphis

Wed 10/28

1:38 pm-8:01 pm

1 stop5h 23m

Key West

Wed 11/4

7:40 am-12:53 pm

1 stop6h 13m

$309

JacksonKey West

JAN Jackson-Evers Intl - EYW Key West

JANEYW

Jackson-Evers Intl

Tue 1/26

3:42 pm-9:47 pm

1 stop5h 05m

Key West

Sat 1/30

6:43 pm-11:30 pm

1 stop5h 47m

$319

JacksonKey West

JAN Jackson-Evers Intl - EYW Key West

JANEYW

Jackson-Evers Intl

Sat 1/30

12:50 pm-9:47 pm

1 stop7h 57m

Key West

Wed 2/3

6:43 pm-11:30 pm

1 stop5h 47m

$319

MemphisKey West

MEM Memphis - EYW Key West

MEMEYW

Memphis

Tue 12/22

7:05 am-12:43 pm

1 stop4h 38m

Key West

Tue 12/29

8:03 pm-11:49 pm

1 stop4h 46m

$361

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Mississippi to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Mississippi to Key West?

Allegiant Air, American Airlines, and Delta are the most popular carriers operating from Mississippi to Key West

Cheap Mississippi to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Key West

Fastest flight time

3h 46m

Direct flights

None
The fastest flight from Mississippi to Key West takes 3h 46m
There are no direct flights from Mississippi to Key West. There are no popular flight routes from Mississippi to Key West.
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Frequently asked questions about flying from Mississippi to Key West

  • When did momondo last update prices for flights from Mississippi to Key West Airport?

    Prices for flights from Mississippi to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Mississippi to Key West Airport?

  • How old do you have to be to fly from Mississippi to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Mississippi to Key West

Compare and see reviews for airlines that fly from Mississippi to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $298Free CancellationRating
7.1
11,929 reviews
Search American Airlines flights
DeltaPriceFrom $308Free CancellationRating
7.8
8,502 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Key West?

Finding the right flight to Key West from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Key West quick and easy, saving you time and money.

Can I find flights from Mississippi to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to Key West?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Mississippi to Key West.

I’m not ready to book a flight from Mississippi to Key West right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Mississippi to Key West flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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