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Cheap flights from Minneapolis to Florence from $228

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Florence departing on 10/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Minneapolis to Florence

Cheap round-trip flights

American Airlines Logo
6:00 am - 5:12 pmMSP-FLO
10h 12m2 stops
American Airlines Logo
6:14 am - 4:51 pmFLO-MSP
11h 37m2 stops
$418American Airlines
Find Deal
Tue, Sep 9 - Tue, Sep 16
American Airlines Logo
10:58 am - 5:12 pmMSP-FLO
5h 14m1 stop
American Airlines Logo
6:14 am - 10:08 amFLO-MSP
4h 54m1 stop
$431American Airlines
Find Deal
Tue, Sep 9 - Tue, Sep 16
American Airlines Logo
10:58 am - 5:12 pmMSP-FLO
5h 14m1 stop
American Airlines Logo
6:14 am - 4:51 pmFLO-MSP
11h 37m2 stops
$436American Airlines
Find Deal
Tue, Sep 9 - Tue, Sep 16
American Airlines Logo
6:00 am - 2:04 pmMSP-FLO
7h 04m1 stop
American Airlines Logo
5:14 am - 9:08 amFLO-MSP
4h 54m1 stop
$475American Airlines
Find Deal
Sun, Oct 12 - Sun, Oct 19
American Airlines Logo
6:08 am - 11:46 amMSP-FLO
4h 38m1 stop
American Airlines Logo
11:15 am - 5:09 pmFLO-MSP
6h 54m1 stop
$480American Airlines
Find Deal
Wed, Aug 27 - Sun, Aug 31
American Airlines Logo
6:00 am - 3:04 pmMSP-FLO
8h 04m2 stops
American Airlines Logo
9:05 am - 12:54 pmFLO-MSP
4h 49m1 stop
$485American Airlines
Find Deal
Wed, Aug 27 - Sun, Aug 31
American Airlines Logo
11:26 am - 11:02 pmMSP-FLO
10h 36m2 stops
American Airlines Logo
11:15 am - 7:18 pmFLO-MSP
9h 03m2 stops
$490American Airlines
Find Deal
Wed, Aug 27 - Sun, Aug 31
American Airlines Logo
6:00 am - 2:09 pmMSP-FLO
7h 09m1 stop
American Airlines Logo
11:15 am - 5:08 pmFLO-MSP
6h 53m1 stop
$500American Airlines
Find Deal
Sun, Aug 24 - Sat, Aug 30
American Airlines Logo
6:00 am - 2:09 pmMSP-FLO
7h 09m1 stop
American Airlines Logo
9:05 am - 5:35 pmFLO-MSP
9h 30m2 stops
$505American Airlines
Find Deal
Sun, Aug 24 - Sat, Aug 30
American Airlines Logo
6:00 am - 2:09 pmMSP-FLO
7h 09m2 stops
American Airlines Logo
2:34 pm - 11:47 pmFLO-MSP
10h 13m2 stops
$510American Airlines
Find Deal
Sun, Aug 24 - Sat, Aug 30

American Airlines flights from Minneapolis to Florence, South Carolina

Our best American Airlines deals on Minneapolis to Florence, South Carolina flight tickets
American Airlines
Sep 9
MSP6:00 amMinneapolis St Paul
10h 12m
2 stops
FLO5:12 pmFlorence
Sep 16
FLO6:14 amFlorence
11h 37m
2 stops
MSP4:51 pmMinneapolis St Paul
$418
Find similar
American Airlines
Sep 9
MSP10:58 amMinneapolis St Paul
5h 14m
1 stop
FLO5:12 pmFlorence
Sep 16
FLO6:14 amFlorence
4h 54m
1 stop
MSP10:08 amMinneapolis St Paul
$431
Find similar
American Airlines
Sep 9
MSP10:58 amMinneapolis St Paul
5h 14m
1 stop
FLO5:12 pmFlorence
Sep 16
FLO6:14 amFlorence
11h 37m
2 stops
MSP4:51 pmMinneapolis St Paul
$436
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Minneapolis to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 9/9

6:00 am-5:12 pm

2 stops10h 12m

Florence

Tue 9/16

6:14 am-4:51 pm

2 stops11h 37m

$418

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 9/9

10:58 am-5:12 pm

1 stop5h 14m

Florence

Tue 9/16

6:14 am-10:08 am

1 stop4h 54m

$431

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 9/9

10:58 am-5:12 pm

1 stop5h 14m

Florence

Tue 9/16

6:14 am-4:51 pm

2 stops11h 37m

$436

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sun 10/12

6:00 am-2:04 pm

1 stop7h 04m

Florence

Sun 10/19

5:14 am-9:08 am

1 stop4h 54m

$475

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Wed 8/27

6:08 am-11:46 am

1 stop4h 38m

Florence

Sun 8/31

11:15 am-5:09 pm

1 stop6h 54m

$480

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Wed 8/27

6:00 am-3:04 pm

2 stops8h 04m

Florence

Sun 8/31

9:05 am-12:54 pm

1 stop4h 49m

$485

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Wed 8/27

11:26 am-11:02 pm

2 stops10h 36m

Florence

Sun 8/31

11:15 am-7:18 pm

2 stops9h 03m

$490

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sun 8/24

6:00 am-2:09 pm

1 stop7h 09m

Florence

Sat 8/30

11:15 am-5:08 pm

1 stop6h 53m

$500

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sun 8/24

6:00 am-2:09 pm

1 stop7h 09m

Florence

Sat 8/30

9:05 am-5:35 pm

2 stops9h 30m

$505

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sun 8/24

6:00 am-2:09 pm

2 stops7h 09m

Florence

Sat 8/30

2:34 pm-11:47 pm

2 stops10h 13m

$510

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Minneapolis to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Minneapolis St Paul to Florence?

American Airlines is the most popular carrier operating from Minneapolis St Paul to Florence

What airlines fly to Florence, South Carolina?

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to Florence, South Carolina from Minneapolis according to our data. Delta is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 7 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Minneapolis to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Minneapolis to Florence, South Carolina (MSP to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Florence, South Carolina

Best Price Found

$228

Fastest flight time

4h 38m

Direct flights

None

Airports in Florence, South Carolina

1 airport
The best one-way flight to Florence, South Carolina from Minneapolis in the past 72 hours is $228. The best round-trip flight deal from Minneapolis to Florence, South Carolina found on momondo in the last 72 hours is $418.
The fastest flight from Minneapolis to Florence, South Carolina takes 4h 38m
There are no direct flights from Minneapolis to Florence, South Carolina. Popular non-direct route for this connection is Minneapolis St Paul Airport - Florence Airport.
There is 1 airport near Florence, South Carolina: Florence (FLO)
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  • How far is Minneapolis St Paul to Florence by plane?

    Minneapolis St Paul and Florence are 1032.0 mi apart from one another. Flights usually cover this in 4h 38m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Florence Airport?

    Prices for flights from Minneapolis St Paul Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Minneapolis St Paul Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Florence?

It is quick and easy to find Minneapolis to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Minneapolis to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Minneapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Minneapolis to Florence?

Once all potential Minneapolis to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Minneapolis to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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