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Cheap flights from Minneapolis to Florence from $424

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Florence departing on 3/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Minneapolis to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:11 am - 2:10 pm
MSP
-
FLO
6h 59m
1 stop
American Airlines Logo
5:09 am - 9:45 am
FLO
-
MSP
5h 36m
1 stop
$435American Airlines
Sat, Jun 27 - Sat, Jul 4
American Airlines Logo
6:11 am - 2:10 pm
MSP
-
FLO
6h 59m
1 stop
American Airlines Logo
5:09 am - 3:32 pm
FLO
-
MSP
11h 23m
2 stops
$440American Airlines
Sat, Jun 27 - Sat, Jul 4
American Airlines Logo
3:02 pm - 11:08 pm
MSP
-
FLO
7h 06m
1 stop
American Airlines Logo
6:25 pm - 11:23 pm
FLO
-
MSP
5h 58m
1 stop
$442American Airlines
Tue, Mar 17 - Sat, Mar 21
American Airlines Logo
7:03 am - 5:21 pm
MSP
-
FLO
9h 18m
2 stops
American Airlines Logo
6:25 pm - 11:23 pm
FLO
-
MSP
5h 58m
1 stop
$447American Airlines
Tue, Mar 17 - Sat, Mar 21
American Airlines Logo
10:53 am - 5:21 pm
MSP
-
FLO
5h 28m
1 stop
American Airlines Logo
6:25 pm - 11:23 pm
FLO
-
MSP
5h 58m
1 stop
$462American Airlines
Tue, Mar 17 - Sat, Mar 21
American Airlines Logo
7:03 am - 5:21 pm
MSP
-
FLO
9h 18m
2 stops
American Airlines Logo
6:25 pm - 11:23 pm
FLO
-
MSP
5h 58m
1 stop
$467American Airlines
Tue, Mar 17 - Sat, Mar 21
American Airlines Logo
6:11 am - 2:10 pm
MSP
-
FLO
6h 59m
1 stop
American Airlines Logo
5:09 am - 9:45 am
FLO
-
MSP
5h 36m
1 stop
$491American Airlines
Sun, Jun 28 - Sat, Jul 4
American Airlines Logo
5:05 pm - 11:57 pm
MSP
-
FLO
5h 52m
1 stop
American Airlines Logo
6:15 am - 10:11 am
FLO
-
MSP
4h 56m
1 stop
$494American Airlines
Fri, Mar 20 - Tue, Mar 24
American Airlines Logo
6:11 am - 2:10 pm
MSP
-
FLO
6h 59m
1 stop
American Airlines Logo
2:36 pm - 10:13 pm
FLO
-
MSP
8h 37m
2 stops
$496American Airlines
Sun, Jun 28 - Sat, Jul 4
American Airlines Logo
6:11 am - 2:10 pm
MSP
-
FLO
6h 59m
1 stop
American Airlines Logo
5:09 am - 9:45 am
FLO
-
MSP
5h 36m
1 stop
$511American Airlines
Fri, Jun 26 - Sat, Jul 4

American Airlines flights from Minneapolis to Florence, South Carolina

Our best American Airlines deals on Minneapolis to Florence, South Carolina flight tickets
American Airlines
Jun 27
MSP6:11 amMinneapolis St Paul
6h 59m
1 stop
FLO2:10 pmFlorence
Jul 4
FLO5:09 amFlorence
5h 36m
1 stop
MSP9:45 amMinneapolis St Paul
$435
American Airlines
Jun 27
MSP6:11 amMinneapolis St Paul
6h 59m
1 stop
FLO2:10 pmFlorence
Jul 4
FLO5:09 amFlorence
11h 23m
2 stops
MSP3:32 pmMinneapolis St Paul
$440
American Airlines
Mar 17
MSP3:02 pmMinneapolis St Paul
7h 06m
1 stop
FLO11:08 pmFlorence
Mar 21
FLO6:25 pmFlorence
5h 58m
1 stop
MSP11:23 pmMinneapolis St Paul
$442

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from Minneapolis to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 6/27

6:11 am-2:10 pm

1 stop6h 59m

Florence

Sat 7/4

5:09 am-9:45 am

1 stop5h 36m

$435

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 6/27

6:11 am-2:10 pm

1 stop6h 59m

Florence

Sat 7/4

5:09 am-3:32 pm

2 stops11h 23m

$440

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 3/17

3:02 pm-11:08 pm

1 stop7h 06m

Florence

Sat 3/21

6:25 pm-11:23 pm

1 stop5h 58m

$442

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 3/17

7:03 am-5:21 pm

2 stops9h 18m

Florence

Sat 3/21

6:25 pm-11:23 pm

1 stop5h 58m

$447

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 3/17

10:53 am-5:21 pm

1 stop5h 28m

Florence

Sat 3/21

6:25 pm-11:23 pm

1 stop5h 58m

$462

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 3/17

7:03 am-5:21 pm

2 stops9h 18m

Florence

Sat 3/21

6:25 pm-11:23 pm

1 stop5h 58m

$467

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sun 6/28

6:11 am-2:10 pm

1 stop6h 59m

Florence

Sat 7/4

5:09 am-9:45 am

1 stop5h 36m

$491
Quickest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 3/20

5:05 pm-11:57 pm

1 stop5h 52m

Florence

Tue 3/24

6:15 am-10:11 am

1 stop4h 56m

$494

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sun 6/28

6:11 am-2:10 pm

1 stop6h 59m

Florence

Sat 7/4

2:36 pm-10:13 pm

2 stops8h 37m

$496

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 6/26

6:11 am-2:10 pm

1 stop6h 59m

Florence

Sat 7/4

5:09 am-9:45 am

1 stop5h 36m

$511

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Minneapolis to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Minneapolis St Paul to Florence?

American Airlines is the most popular carrier operating from Minneapolis St Paul to Florence

What airlines fly to Florence, South Carolina?

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to Florence, South Carolina from Minneapolis according to our data. Delta is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Minneapolis to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Minneapolis to Florence, South Carolina (MSP to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Florence, South Carolina

Fastest flight time

5h 00m

Direct flights

None
The fastest flight from Minneapolis to Florence, South Carolina takes 5h 00m
There are no direct flights from Minneapolis to Florence, South Carolina. There are no popular flight routes from Minneapolis to Florence, South Carolina.
Search flight deals

  • How far is Minneapolis St Paul to Florence by plane?

    Minneapolis St Paul and Florence are 1032.0 mi apart from one another. Flights usually cover this in 5h 00m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Florence Airport?

    Prices for flights from Minneapolis St Paul Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Minneapolis St Paul Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Florence?

It is quick and easy to find Minneapolis to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Minneapolis to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Minneapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Minneapolis to Florence?

Once all potential Minneapolis to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Minneapolis to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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