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Cheap flights from Minneapolis to Florence from $335

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Florence departing on 5/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Minneapolis to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:57 pm - 10:42 pm
MSP
-
FLO
6h 45m
1 stop
American Airlines Logo
5:05 am - 10:05 am
FLO
-
MSP
6h 00m
1 stop
$335American Airlines
Tue, May 19 - Sat, May 23
American Airlines Logo
11:29 am - 10:42 pm
MSP
-
FLO
10h 13m
2 stops
American Airlines Logo
5:05 am - 10:05 am
FLO
-
MSP
6h 00m
1 stop
$340American Airlines
Tue, May 19 - Sat, May 23
American Airlines Logo
11:29 am - 10:42 pm
MSP
-
FLO
10h 13m
2 stops
American Airlines Logo
2:35 pm - 11:59 pm
FLO
-
MSP
10h 24m
2 stops
$345American Airlines
Tue, May 19 - Sat, May 23
American Airlines Logo
2:57 pm - 10:42 pm
MSP
-
FLO
6h 45m
1 stop
American Airlines Logo
5:05 am - 1:24 pm
FLO
-
MSP
9h 19m
2 stops
$360American Airlines
Tue, May 19 - Sun, May 24
American Airlines Logo
11:29 am - 10:42 pm
MSP
-
FLO
10h 13m
2 stops
American Airlines Logo
5:05 am - 12:26 pm
FLO
-
MSP
8h 21m
2 stops
$366American Airlines
Tue, May 19 - Sun, May 24
American Airlines Logo
10:28 am - 3:50 pm
MSP
-
FLO
4h 22m
1 stop
American Airlines Logo
5:20 am - 9:48 am
FLO
-
MSP
5h 28m
1 stop
$555American Airlines
Sat, Apr 25 - Sun, Apr 26
American Airlines Logo
10:44 am - 9:47 pm
MSP
-
FLO
10h 03m
2 stops
American Airlines Logo
5:20 am - 9:48 am
FLO
-
MSP
5h 28m
1 stop
$560American Airlines
Sat, Apr 25 - Sun, Apr 26
American Airlines Logo
1:09 pm - 9:47 pm
MSP
-
FLO
7h 38m
2 stops
American Airlines Logo
4:16 pm - 11:59 pm
FLO
-
MSP
8h 43m
2 stops
$565American Airlines
Sat, Apr 25 - Mon, Apr 27
American Airlines Logo
10:28 am - 3:50 pm
MSP
-
FLO
4h 22m
1 stop
American Airlines Logo
5:20 am - 9:48 am
FLO
-
MSP
5h 28m
1 stop
$591American Airlines
Sat, Apr 25 - Mon, Apr 27
American Airlines Logo
11:29 am - 9:47 pm
MSP
-
FLO
9h 18m
2 stops
American Airlines Logo
5:20 am - 10:54 am
FLO
-
MSP
6h 34m
2 stops
$704American Airlines
Sat, Apr 25 - Sun, Apr 26

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American Airlines flights from Minneapolis to Florence, South Carolina

Our best American Airlines deals on Minneapolis to Florence, South Carolina flight tickets
American Airlines
May 19
MSP2:57 pmMinneapolis St Paul
6h 45m
1 stop
FLO10:42 pmFlorence
May 23
FLO5:05 amFlorence
6h 00m
1 stop
MSP10:05 amMinneapolis St Paul
$335
American Airlines
May 19
MSP11:29 amMinneapolis St Paul
10h 13m
2 stops
FLO10:42 pmFlorence
May 23
FLO5:05 amFlorence
6h 00m
1 stop
MSP10:05 amMinneapolis St Paul
$340
American Airlines
May 19
MSP11:29 amMinneapolis St Paul
10h 13m
2 stops
FLO10:42 pmFlorence
May 23
FLO2:35 pmFlorence
10h 24m
2 stops
MSP11:59 pmMinneapolis St Paul
$345

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Minneapolis to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 5/19

2:57 pm-10:42 pm

1 stop6h 45m

Florence

Sat 5/23

5:05 am-10:05 am

1 stop6h 00m

$335

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 5/19

11:29 am-10:42 pm

2 stops10h 13m

Florence

Sat 5/23

5:05 am-10:05 am

1 stop6h 00m

$340

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 5/19

11:29 am-10:42 pm

2 stops10h 13m

Florence

Sat 5/23

2:35 pm-11:59 pm

2 stops10h 24m

$345

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 5/19

2:57 pm-10:42 pm

1 stop6h 45m

Florence

Sun 5/24

5:05 am-1:24 pm

2 stops9h 19m

$360

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 5/19

11:29 am-10:42 pm

2 stops10h 13m

Florence

Sun 5/24

5:05 am-12:26 pm

2 stops8h 21m

$366
Quickest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 4/25

10:28 am-3:50 pm

1 stop4h 22m

Florence

Sun 4/26

5:20 am-9:48 am

1 stop5h 28m

$555

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 4/25

10:44 am-9:47 pm

2 stops10h 03m

Florence

Sun 4/26

5:20 am-9:48 am

1 stop5h 28m

$560

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 4/25

1:09 pm-9:47 pm

2 stops7h 38m

Florence

Mon 4/27

4:16 pm-11:59 pm

2 stops8h 43m

$565

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 4/25

10:28 am-3:50 pm

1 stop4h 22m

Florence

Mon 4/27

5:20 am-9:48 am

1 stop5h 28m

$591

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 4/25

11:29 am-9:47 pm

2 stops9h 18m

Florence

Sun 4/26

5:20 am-10:54 am

2 stops6h 34m

$704

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Minneapolis to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to Florence, South Carolina from Minneapolis according to our data. Delta is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Minneapolis to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Minneapolis to Florence, South Carolina (MSP to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Florence, South Carolina

Fastest flight time

6h 45m

Direct flights

None
The fastest flight from Minneapolis to Florence, South Carolina takes 6h 45m
There are no direct flights from Minneapolis to Florence, South Carolina. There are no popular flight routes from Minneapolis to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Minneapolis to Florence, South Carolina

  • How far is Minneapolis St Paul to Florence by plane?

    Minneapolis St Paul and Florence are 1032.0 mi apart from one another. Flights usually cover this in 6h 45m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Florence Airport?

    Prices for flights from Minneapolis St Paul Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Minneapolis St Paul Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Darlington
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Florence?

It is quick and easy to find Minneapolis to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Minneapolis to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Minneapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Minneapolis to Florence?

Once all potential Minneapolis to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Minneapolis to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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