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Cheap flights from Minneapolis to Florence from $448

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Florence departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Minneapolis to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
9:16 am - 10:58 pm
MSP
-
FLO
12h 42m
2 stops
American Airlines Logo
1:43 pm - 12:22 am
FLO
-
MSP
11h 39m
2 stops
$448American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
7:25 am - 1:18 pm
MSP
-
FLO
4h 53m
1 stop
American Airlines Logo
6:24 am - 5:44 pm
FLO
-
MSP
12h 20m
2 stops
$469American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
5:45 pm - 12:03 am
MSP
-
FLO
5h 18m
1 stop
American Airlines Logo
11:11 am - 11:02 pm
FLO
-
MSP
12h 51m
2 stops
$475American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
3:01 pm - 10:58 pm
MSP
-
FLO
6h 57m
1 stop
American Airlines Logo
6:24 am - 10:26 am
FLO
-
MSP
5h 02m
1 stop
$490American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
6:20 pm - 10:45 am
MSP
-
FLO
15h 25m
2 stops
American Airlines Logo
11:11 am - 11:02 pm
FLO
-
MSP
12h 51m
2 stops
$515American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
6:20 pm - 10:45 am
MSP
-
FLO
15h 25m
2 stops
American Airlines Logo
11:11 am - 11:02 pm
FLO
-
MSP
12h 51m
2 stops
$517American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
9:59 am - 6:07 pm
MSP
-
FLO
7h 08m
1 stop
American Airlines Logo
6:33 pm - 11:08 pm
FLO
-
MSP
5h 35m
1 stop
$518American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
7:45 pm - 10:45 am
MSP
-
FLO
14h 00m
2 stops
American Airlines Logo
11:11 am - 11:02 pm
FLO
-
MSP
12h 51m
2 stops
$596American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
8:10 am - 10:59 pm
MSP
-
FLO
13h 49m
2 stops
American Airlines Logo
3:22 pm - 9:06 pm
FLO
-
MSP
6h 44m
1 stop
$805American Airlines
Mon, Aug 10 - Fri, Aug 14
American Airlines Logo
8:10 am - 10:59 pm
MSP
-
FLO
13h 49m
2 stops
American Airlines Logo
6:24 am - 3:46 pm
FLO
-
MSP
10h 22m
2 stops
$845American Airlines
Mon, Aug 10 - Fri, Aug 14

American Airlines flights from Minneapolis to Florence, South Carolina

Our best American Airlines deals on Minneapolis to Florence, South Carolina flight tickets
American Airlines
Sep 26
MSP9:16 amMinneapolis St Paul
12h 42m
2 stops
FLO10:58 pmFlorence
Oct 3
FLO1:43 pmFlorence
11h 39m
2 stops
MSP12:22 amMinneapolis St Paul
$448
American Airlines
Sep 26
MSP7:25 amMinneapolis St Paul
4h 53m
1 stop
FLO1:18 pmFlorence
Oct 3
FLO6:24 amFlorence
12h 20m
2 stops
MSP5:44 pmMinneapolis St Paul
$469
American Airlines
Nov 6
MSP5:45 pmMinneapolis St Paul
5h 18m
1 stop
FLO12:03 amFlorence
Nov 10
FLO11:11 amFlorence
12h 51m
2 stops
MSP11:02 pmMinneapolis St Paul
$475

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 5, 2026.
Use the filters below to find and compare flights from Minneapolis to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 9/26

9:16 am-10:58 pm

2 stops12h 42m

Florence

Sat 10/3

1:43 pm-12:22 am

2 stops11h 39m

$448

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 9/26

7:25 am-1:18 pm

1 stop4h 53m

Florence

Sat 10/3

6:24 am-5:44 pm

2 stops12h 20m

$469

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

5:45 pm-12:03 am

1 stop5h 18m

Florence

Tue 11/10

11:11 am-11:02 pm

2 stops12h 51m

$475
Quickest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 9/26

3:01 pm-10:58 pm

1 stop6h 57m

Florence

Sat 10/3

6:24 am-10:26 am

1 stop5h 02m

$490

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

6:20 pm-10:45 am

2 stops15h 25m

Florence

Tue 11/10

11:11 am-11:02 pm

2 stops12h 51m

$515

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

6:20 pm-10:45 am

2 stops15h 25m

Florence

Tue 11/10

11:11 am-11:02 pm

2 stops12h 51m

$517

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

9:59 am-6:07 pm

1 stop7h 08m

Florence

Tue 11/10

6:33 pm-11:08 pm

1 stop5h 35m

$518

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

7:45 pm-10:45 am

2 stops14h 00m

Florence

Tue 11/10

11:11 am-11:02 pm

2 stops12h 51m

$596

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 8/10

8:10 am-10:59 pm

2 stops13h 49m

Florence

Fri 8/14

3:22 pm-9:06 pm

1 stop6h 44m

$805

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 8/10

8:10 am-10:59 pm

2 stops13h 49m

Florence

Fri 8/14

6:24 am-3:46 pm

2 stops10h 22m

$845

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Minneapolis to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to Florence, South Carolina from Minneapolis according to our data. Delta is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 7 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Minneapolis to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Minneapolis to Florence, South Carolina (MSP to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Florence, South Carolina

Fastest flight time

5h 14m

Direct flights

None
The fastest flight from Minneapolis to Florence, South Carolina takes 5h 14m
There are no direct flights from Minneapolis to Florence, South Carolina. There are no popular flight routes from Minneapolis to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Minneapolis to Florence, South Carolina

  • How far is Minneapolis St Paul to Florence by plane?

    Minneapolis St Paul and Florence are 1032.0 mi apart from one another. Flights usually cover this in 5h 14m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Florence Airport?

    Prices for flights from Minneapolis St Paul Airport to Florence Airport refresh daily.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to Florence Airport?

  • How old do you have to be to fly from Minneapolis St Paul Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Minneapolis to Florence, South Carolina?

Best airlines flying from Minneapolis to Florence, South Carolina

Compare and see reviews for airlines that fly from Minneapolis to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $295Free CancellationRating
7.1
11,645 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Florence?

It is quick and easy to find Minneapolis to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Minneapolis to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Minneapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Minneapolis to Florence?

Once all potential Minneapolis to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Minneapolis to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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