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Cheap flights from Milwaukee to Knoxville from $135

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Knoxville departing on 7/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Milwaukee to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:31 am - 4:11 pm
MKE
-
TYS
6h 40m
1 stop
American Airlines Logo
11:08 am - 4:41 pm
TYS
-
MKE
6h 33m
1 stop
$269American Airlines
Wed, Sep 16 - Tue, Sep 22
Southwest Logo
6:40 am - 2:20 pm
MKE
-
TYS
6h 40m
2 stops
Southwest Logo
1:00 pm - 8:45 pm
TYS
-
MKE
8h 45m
1 stop
$274Southwest
Tue, Aug 11 - Mon, Aug 17
Delta Logo
5:40 am - 11:01 am
MKE
-
TYS
4h 21m
1 stop
Delta Logo
7:25 am - 11:30 am
TYS
-
MKE
5h 05m
1 stop
$279Delta
Wed, Oct 14 - Sat, Oct 17
Southwest Logo
8:20 am - 7:50 pm
MKE
-
TYS
10h 30m
2 stops
Southwest Logo
8:05 am - 12:00 pm
TYS
-
MKE
4h 55m
1 stop
$280Southwest
Wed, Sep 9 - Tue, Sep 15
Southwest Logo
8:20 am - 7:50 pm
MKE
-
TYS
10h 30m
2 stops
Southwest Logo
7:00 am - 3:50 pm
TYS
-
MKE
9h 50m
2 stops
$285Southwest
Wed, Sep 9 - Tue, Sep 15
Southwest Logo
6:40 am - 2:20 pm
MKE
-
TYS
6h 40m
2 stops
Southwest Logo
1:00 pm - 8:45 pm
TYS
-
MKE
8h 45m
1 stop
$295Southwest
Tue, Aug 11 - Mon, Aug 17
American Airlines Logo
5:02 am - 12:30 pm
MKE
-
TYS
6h 28m
1 stop
American Airlines Logo
7:16 pm - 11:09 pm
TYS
-
MKE
4h 53m
1 stop
$299American Airlines
Tue, Jul 21 - Fri, Jul 24
United Airlines Logo
5:00 am - 9:45 am
MKE
-
TYS
3h 45m
1 stop
United Airlines Logo
6:00 am - 10:00 am
TYS
-
MKE
5h 00m
1 stop
$300United Airlines
Mon, Sep 28 - Fri, Oct 2
Southwest Logo
8:00 am - 7:55 pm
MKE
-
TYS
10h 55m
2 stops
Southwest Logo
7:10 am - 10:10 am
TYS
-
MKE
4h 00m
1 stop
$304Southwest
Fri, Aug 28 - Mon, Aug 31
Southwest Logo
8:20 am - 7:50 pm
MKE
-
TYS
10h 30m
2 stops
Southwest Logo
12:40 pm - 8:45 pm
TYS
-
MKE
9h 05m
1 stop
$306Southwest
Wed, Aug 19 - Mon, Aug 24

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American Airlines flights from Milwaukee to Knoxville

Our best American Airlines deals on Milwaukee to Knoxville flight tickets
American Airlines
Sep 16
MKE8:31 amMilwaukee-Mitchell
6h 40m
1 stop
TYS4:11 pmKnoxville McGhee Tyson
Sep 22
TYS11:08 amKnoxville McGhee Tyson
6h 33m
1 stop
MKE4:41 pmMilwaukee-Mitchell
$269
American Airlines
Jul 21
MKE5:02 amMilwaukee-Mitchell
6h 28m
1 stop
TYS12:30 pmKnoxville McGhee Tyson
Jul 24
TYS7:16 pmKnoxville McGhee Tyson
4h 53m
1 stop
MKE11:09 pmMilwaukee-Mitchell
$299
American Airlines
Sep 11
MKE5:03 amMilwaukee-Mitchell
6h 27m
1 stop
TYS12:30 pmKnoxville McGhee Tyson
Sep 13
TYS4:51 pmKnoxville McGhee Tyson
4h 38m
1 stop
MKE8:29 pmMilwaukee-Mitchell
$313

Delta flights from Milwaukee to Knoxville

Our best Delta deals on Milwaukee to Knoxville flight tickets
Delta
Sep 3
MKE5:19 pmMilwaukee-Mitchell
5h 33m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
Sep 8
TYS6:00 amKnoxville McGhee Tyson
6h 49m
1 stop
MKE11:49 amMilwaukee-Mitchell
$279
Delta
Jul 17
MKE12:58 pmMilwaukee-Mitchell
5h 55m
1 stop
TYS7:53 pmKnoxville McGhee Tyson
Jul 21
TYS7:43 pmKnoxville McGhee Tyson
5h 13m
1 stop
MKE11:56 pmMilwaukee-Mitchell
$311
Delta
Sep 8
MKE2:55 pmMilwaukee-Mitchell
6h 32m
1 stop
TYS10:27 pmKnoxville McGhee Tyson
Sep 14
TYS6:13 pmKnoxville McGhee Tyson
4h 17m
1 stop
MKE9:30 pmMilwaukee-Mitchell
$319

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Milwaukee to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Wed 9/16

8:31 am-4:11 pm

1 stop6h 40m

Knoxville McGhee Tyson

Tue 9/22

11:08 am-4:41 pm

1 stop6h 33m

$269

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Tue 8/11

6:40 am-2:20 pm

2 stops6h 40m

Knoxville McGhee Tyson

Mon 8/17

1:00 pm-8:45 pm

1 stop8h 45m

$274

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Wed 10/14

5:40 am-11:01 am

1 stop4h 21m

Knoxville McGhee Tyson

Sat 10/17

7:25 am-11:30 am

1 stop5h 05m

$279

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Wed 9/9

8:20 am-7:50 pm

2 stops10h 30m

Knoxville McGhee Tyson

Tue 9/15

8:05 am-12:00 pm

1 stop4h 55m

$280

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Wed 9/9

8:20 am-7:50 pm

2 stops10h 30m

Knoxville McGhee Tyson

Tue 9/15

7:00 am-3:50 pm

2 stops9h 50m

$285

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Tue 8/11

6:40 am-2:20 pm

2 stops6h 40m

Knoxville McGhee Tyson

Mon 8/17

1:00 pm-8:45 pm

1 stop8h 45m

$295

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Tue 7/21

5:02 am-12:30 pm

1 stop6h 28m

Knoxville McGhee Tyson

Fri 7/24

7:16 pm-11:09 pm

1 stop4h 53m

$299
Quickest round-trip

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Mon 9/28

5:00 am-9:45 am

1 stop3h 45m

Knoxville McGhee Tyson

Fri 10/2

6:00 am-10:00 am

1 stop5h 00m

$300

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Fri 8/28

8:00 am-7:55 pm

2 stops10h 55m

Knoxville McGhee Tyson

Mon 8/31

7:10 am-10:10 am

1 stop4h 00m

$304

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Wed 8/19

8:20 am-7:50 pm

2 stops10h 30m

Knoxville McGhee Tyson

Mon 8/24

12:40 pm-8:45 pm

1 stop9h 05m

$306

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Milwaukee to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Milwaukee and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Milwaukee, with most prices found around $242. If you aren’t able to travel during the month of January, then book flights to Knoxville from Milwaukee during September instead. Flights to Knoxville in September, while not as cheap as those in January, still average around $283.

How have Milwaukee to Knoxville flight prices changed over time?

As of July 2026, prices for Milwaukee to Knoxville flights are approximately 37% cheaper when compared to flights at the same time last year.

When to book flights from Milwaukee to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Knoxville (MKE to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Knoxville

Fastest flight time

3h 25m

Direct flights

None
The fastest flight from Milwaukee to Knoxville takes 3h 25m
There are no direct flights from Milwaukee to Knoxville. There are no popular flight routes from Milwaukee to Knoxville.
Search flight deals

Frequently asked questions about flying from Milwaukee to Knoxville

  • How far is Milwaukee-Mitchell to Knoxville McGhee Tyson by plane?

    The distance between Milwaukee-Mitchell and Knoxville McGhee Tyson is about 532.7 mi. Flights usually cover this in 3h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Milwaukee to Knoxville?

Best airlines flying from Milwaukee to Knoxville

Compare and see reviews for airlines that fly from Milwaukee to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $144Free CancellationRating
7.8
8,452 reviews
Search Delta flights
United AirlinesPriceFrom $208Free CancellationRating
7.4
9,938 reviews
Search United Airlines flights
American AirlinesPriceFrom $208Free CancellationRating
7.1
11,784 reviews
Search American Airlines flights
SouthwestPriceFrom $243Free CancellationRating
7.9
4,251 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Murphy
Crossville
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Milwaukee to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Milwaukee to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Knoxville?

Once you have performed a search for Milwaukee to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Milwaukee to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Milwaukee are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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