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Cheap flights from Milwaukee to Knoxville from $135

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Knoxville departing on 7/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Milwaukee to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
4:30 pm - 9:10 pm
MKE
-
TYS
3h 40m
1 stop
Southwest Logo
7:00 am - 9:50 am
TYS
-
MKE
3h 50m
1 stop
$269Southwest
Fri, Jul 31 - Tue, Aug 4
Southwest Logo
4:30 pm - 9:10 pm
MKE
-
TYS
3h 40m
1 stop
Southwest Logo
8:00 am - 4:20 pm
TYS
-
MKE
9h 20m
2 stops
$274Southwest
Fri, Jul 31 - Tue, Aug 4
Southwest Logo
5:10 am - 5:00 pm
MKE
-
TYS
10h 50m
1 stop
Southwest Logo
12:45 pm - 10:20 pm
TYS
-
MKE
10h 35m
2 stops
$280Southwest
Tue, Jun 16 - Tue, Jun 23
Southwest Logo
9:25 am - 5:10 pm
MKE
-
TYS
6h 45m
1 stop
Southwest Logo
7:45 pm - 12:15 am
TYS
-
MKE
5h 30m
1 stop
$284Southwest
Wed, Jun 3 - Mon, Jun 8
Southwest Logo
12:30 pm - 7:55 pm
MKE
-
TYS
6h 25m
1 stop
Southwest Logo
7:35 am - 2:45 pm
TYS
-
MKE
8h 10m
2 stops
$289Southwest
Fri, Aug 21 - Sun, Aug 23
Southwest Logo
6:45 am - 5:00 pm
MKE
-
TYS
9h 15m
2 stops
Southwest Logo
8:10 am - 5:15 pm
TYS
-
MKE
10h 05m
2 stops
$290Southwest
Tue, Jun 16 - Tue, Jun 23
Delta Logo
4:59 pm - 9:38 pm
MKE
-
TYS
3h 39m
1 stop
Delta Logo
7:35 am - 11:53 am
TYS
-
MKE
5h 18m
1 stop
$294Delta
Sat, Jul 25 - Thu, Jul 30
Southwest Logo
10:05 am - 9:10 pm
MKE
-
TYS
10h 05m
2 stops
Southwest Logo
7:00 am - 3:50 pm
TYS
-
MKE
9h 50m
2 stops
$295Southwest
Fri, Jul 31 - Tue, Aug 4
Southwest Logo
9:35 am - 9:15 pm
MKE
-
TYS
10h 40m
1 stop
Southwest Logo
6:40 am - 9:45 am
TYS
-
MKE
4h 05m
1 stop
$296Southwest
Tue, Jun 23 - Thu, Jun 25
Southwest Logo
3:30 pm - 9:15 pm
MKE
-
TYS
4h 45m
1 stop
Southwest Logo
7:30 am - 11:50 am
TYS
-
MKE
5h 20m
1 stop
$299Southwest
Mon, Jun 1 - Fri, Jun 5

Delta flights from Milwaukee to Knoxville

Our best Delta deals on Milwaukee to Knoxville flight tickets
Delta
Jul 25
MKE4:59 pmMilwaukee-Mitchell
3h 39m
1 stop
TYS9:38 pmKnoxville McGhee Tyson
Jul 30
TYS7:35 amKnoxville McGhee Tyson
5h 18m
1 stop
MKE11:53 amMilwaukee-Mitchell
$294
Delta
Oct 14
MKE1:00 pmMilwaukee-Mitchell
3h 27m
1 stop
TYS5:27 pmKnoxville McGhee Tyson
Oct 17
TYS11:30 amKnoxville McGhee Tyson
5h 37m
1 stop
MKE4:07 pmMilwaukee-Mitchell
$320
Delta
May 25
MKE10:13 amMilwaukee-Mitchell
5h 58m
1 stop
TYS5:11 pmKnoxville McGhee Tyson
May 29
TYS3:30 pmKnoxville McGhee Tyson
6h 32m
1 stop
MKE9:02 pmMilwaukee-Mitchell
$328

Southwest flights from Milwaukee to Knoxville

Our best Southwest deals on Milwaukee to Knoxville flight tickets
Southwest
Jul 31
MKE4:30 pmMilwaukee-Mitchell
3h 40m
1 stop
TYS9:10 pmKnoxville McGhee Tyson
Aug 4
TYS7:00 amKnoxville McGhee Tyson
3h 50m
1 stop
MKE9:50 amMilwaukee-Mitchell
$269
Southwest
Jul 31
MKE4:30 pmMilwaukee-Mitchell
3h 40m
1 stop
TYS9:10 pmKnoxville McGhee Tyson
Aug 4
TYS8:00 amKnoxville McGhee Tyson
9h 20m
2 stops
MKE4:20 pmMilwaukee-Mitchell
$274
Southwest
Jun 16
MKE5:10 amMilwaukee-Mitchell
10h 50m
1 stop
TYS5:00 pmKnoxville McGhee Tyson
Jun 23
TYS12:45 pmKnoxville McGhee Tyson
10h 35m
2 stops
MKE10:20 pmMilwaukee-Mitchell
$280

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Milwaukee to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Fri 7/31

4:30 pm-9:10 pm

1 stop3h 40m

Knoxville McGhee Tyson

Tue 8/4

7:00 am-9:50 am

1 stop3h 50m

$269

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Fri 7/31

4:30 pm-9:10 pm

1 stop3h 40m

Knoxville McGhee Tyson

Tue 8/4

8:00 am-4:20 pm

2 stops9h 20m

$274

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Tue 6/16

5:10 am-5:00 pm

1 stop10h 50m

Knoxville McGhee Tyson

Tue 6/23

12:45 pm-10:20 pm

2 stops10h 35m

$280

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Wed 6/3

9:25 am-5:10 pm

1 stop6h 45m

Knoxville McGhee Tyson

Mon 6/8

7:45 pm-12:15 am

1 stop5h 30m

$284

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Fri 8/21

12:30 pm-7:55 pm

1 stop6h 25m

Knoxville McGhee Tyson

Sun 8/23

7:35 am-2:45 pm

2 stops8h 10m

$289

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Tue 6/16

6:45 am-5:00 pm

2 stops9h 15m

Knoxville McGhee Tyson

Tue 6/23

8:10 am-5:15 pm

2 stops10h 05m

$290

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Sat 7/25

4:59 pm-9:38 pm

1 stop3h 39m

Knoxville McGhee Tyson

Thu 7/30

7:35 am-11:53 am

1 stop5h 18m

$294

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Fri 7/31

10:05 am-9:10 pm

2 stops10h 05m

Knoxville McGhee Tyson

Tue 8/4

7:00 am-3:50 pm

2 stops9h 50m

$295

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Tue 6/23

9:35 am-9:15 pm

1 stop10h 40m

Knoxville McGhee Tyson

Thu 6/25

6:40 am-9:45 am

1 stop4h 05m

$296

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Mon 6/1

3:30 pm-9:15 pm

1 stop4h 45m

Knoxville McGhee Tyson

Fri 6/5

7:30 am-11:50 am

1 stop5h 20m

$299

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Milwaukee to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Milwaukee and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Milwaukee, with most prices found around $242. If you aren’t able to travel during the month of January, then book flights to Knoxville from Milwaukee during July instead. Flights to Knoxville in July, while not as cheap as those in January, still average around $278.

How far in advance should I book a flight from Milwaukee to Knoxville?

You are more likely to see cheaper flights to Knoxville from Milwaukee when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $314 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Milwaukee for as low as $208 on momondo.

How have Milwaukee to Knoxville flight prices changed over time?

As of May 2026, prices for Milwaukee to Knoxville flights are approximately 83% more expensive when compared to flights at the same time last year.

When to book flights from Milwaukee to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Knoxville (MKE to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Knoxville

Fastest flight time

3h 27m

Direct flights

None
The fastest flight from Milwaukee to Knoxville takes 3h 27m
There are no direct flights from Milwaukee to Knoxville. There are no popular flight routes from Milwaukee to Knoxville.
Search flight deals

Frequently asked questions about flying from Milwaukee to Knoxville

  • How far is Milwaukee-Mitchell to Knoxville McGhee Tyson by plane?

    The distance between Milwaukee-Mitchell and Knoxville McGhee Tyson is about 532.7 mi. Flights usually cover this in 3h 27m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Milwaukee to Knoxville?

Best airlines flying from Milwaukee to Knoxville

Compare and see reviews for airlines that fly from Milwaukee to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $144Free CancellationRating
7.9
8,454 reviews
Search Delta flights
United AirlinesPriceFrom $208Free CancellationRating
7.4
9,736 reviews
Search United Airlines flights
American AirlinesPriceFrom $208Free CancellationRating
7.1
11,642 reviews
Search American Airlines flights
SouthwestPriceFrom $243Free CancellationRating
7.9
4,285 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Crossville
Maryville
Murphy
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Milwaukee to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Milwaukee to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Knoxville?

Once you have performed a search for Milwaukee to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Milwaukee to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Milwaukee are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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