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Cheap flights from Milwaukee to Knoxville from $152

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Milwaukee to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:00 am - 10:52 amMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
4h 52m1 stop Washington, D.C. Reagan-National
American Airlines Logo
8:09 am - 11:50 amTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
4h 41m1 stop Charlotte Douglas
$303American Airlines
Tue, Dec 8 - Tue, Dec 15
American Airlines Logo
11:38 am - 4:29 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
3h 51m1 stop Chicago O'Hare Intl
American Airlines Logo
7:52 am - 11:08 amTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
4h 16m1 stop Chicago O'Hare Intl
$303American Airlines
Wed, Nov 11 - Wed, Nov 18
Southwest Logo
4:10 pm - 9:40 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
4h 30m1 stop Baltimore/Washington
Southwest Logo
1:00 pm - 5:20 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
5h 20m1 stop Orlando
$303Southwest
Mon, Dec 21 - Thu, Dec 24
United Airlines Logo
9:17 am - 4:59 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
6h 42m1 stop Chicago O'Hare Intl
United Airlines Logo
10:51 am - 2:58 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
5h 07m1 stop Chicago O'Hare Intl
$303United Airlines
Wed, Nov 11 - Sat, Nov 14
United Airlines Logo
6:47 am - 1:13 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
5h 26m1 stop Chicago O'Hare Intl
United Airlines Logo
5:40 pm - 8:52 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
4h 12m1 stop Chicago O'Hare Intl
$303United Airlines
Wed, Nov 4 - Tue, Nov 10
Multiple Airlines Logo
10:15 am - 12:14 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
24h 59m1 stop Orlando
Multiple Airlines Logo
7:11 pm - 5:26 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
23h 15m1 stop Orlando
$303Multiple Airlines
Thu, Oct 29 - Mon, Nov 23
Southwest Logo
6:20 am - 12:20 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
5h 00m2 stops Chicago Midway Nashville Intl
Southwest Logo
7:10 am - 9:40 amTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
3h 30m1 stop Nashville Intl
$308Southwest
Wed, Nov 11 - Sat, Nov 14
Multiple Airlines Logo
10:15 am - 12:14 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
24h 59m1 stop Orlando
Multiple Airlines Logo
7:11 pm - 5:26 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
23h 15m1 stop Orlando
$309Multiple Airlines
Thu, Oct 29 - Mon, Nov 23
Delta Logo
10:18 am - 3:13 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
3h 55m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:30 am - 11:48 amTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
4h 18m1 stop Atlanta Hartsfield-Jackson
$317Delta
Wed, Dec 9 - Tue, Dec 15
Delta Logo
12:42 pm - 8:09 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
6h 27m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 9:24 amTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
4h 24m1 stop Atlanta Hartsfield-Jackson
$317Delta
Mon, Nov 23 - Tue, Dec 29

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United Airlines flights from Milwaukee to Knoxville

Our best United Airlines deals on Milwaukee to Knoxville flight tickets
United Airlines
Nov 11
MKE9:17 amMilwaukee-Mitchell
6h 42m
1 stop
TYS4:59 pmKnoxville McGhee Tyson
Nov 14
TYS10:51 amKnoxville McGhee Tyson
5h 07m
1 stop
MKE2:58 pmMilwaukee-Mitchell
$303
United Airlines
Feb 1
MKE2:40 pmMilwaukee-Mitchell
5h 25m
1 stop
TYS9:05 pmKnoxville McGhee Tyson
Feb 3
TYS12:20 pmKnoxville McGhee Tyson
6h 28m
1 stop
MKE5:48 pmMilwaukee-Mitchell
$403
United Airlines
Oct 27
MKE10:48 amMilwaukee-Mitchell
5h 11m
1 stop
TYS4:59 pmKnoxville McGhee Tyson
Oct 31
TYS7:00 amKnoxville McGhee Tyson
9h 15m
1 stop
MKE3:15 pmMilwaukee-Mitchell
$473

Southwest flights from Milwaukee to Knoxville

Our best Southwest deals on Milwaukee to Knoxville flight tickets
Southwest
Nov 11
MKE2:15 pmMilwaukee-Mitchell
4h 35m
1 stop
TYS7:50 pmKnoxville McGhee Tyson
Nov 18
TYS1:00 pmKnoxville McGhee Tyson
9h 25m
2 stops
MKE9:25 pmMilwaukee-Mitchell
$308
Southwest
Nov 11
MKE6:20 amMilwaukee-Mitchell
5h 00m
2 stops
TYS12:20 pmKnoxville McGhee Tyson
Nov 18
TYS7:05 amKnoxville McGhee Tyson
8h 00m
2 stops
MKE2:05 pmMilwaukee-Mitchell
$313
Southwest
Nov 11
MKE6:20 amMilwaukee-Mitchell
5h 00m
2 stops
TYS12:20 pmKnoxville McGhee Tyson
Nov 14
TYS7:10 amKnoxville McGhee Tyson
10h 00m
2 stops
MKE4:10 pmMilwaukee-Mitchell
$319

momondo Fare Finder

 
Use the filters below to find and compare flights from Milwaukee to Knoxville that are best for you.

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Price

Cheapest round-trip

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Tue 12/8

5:00 am-10:52 am

1 stop4h 52m

Knoxville McGhee Tyson

Tue 12/15

8:09 am-11:50 am

1 stop4h 41m

$303
Quickest round-trip

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Wed 11/11

11:38 am-4:29 pm

1 stop3h 51m

Knoxville McGhee Tyson

Wed 11/18

7:52 am-11:08 am

1 stop4h 16m

$303

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Mon 12/21

4:10 pm-9:40 pm

1 stop4h 30m

Knoxville McGhee Tyson

Thu 12/24

1:00 pm-5:20 pm

1 stop5h 20m

$303

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Wed 11/11

9:17 am-4:59 pm

1 stop6h 42m

Knoxville McGhee Tyson

Sat 11/14

10:51 am-2:58 pm

1 stop5h 07m

$303

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Wed 11/4

6:47 am-1:13 pm

1 stop5h 26m

Knoxville McGhee Tyson

Tue 11/10

5:40 pm-8:52 pm

1 stop4h 12m

$303

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Thu 10/29

10:15 am-12:14 pm

1 stop24h 59m

Knoxville McGhee Tyson

Mon 11/23

7:11 pm-5:26 pm

1 stop23h 15m

$303

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Wed 11/11

6:20 am-12:20 pm

2 stops5h 00m

Knoxville McGhee Tyson

Sat 11/14

7:10 am-9:40 am

1 stop3h 30m

$308

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Thu 10/29

10:15 am-12:14 pm

1 stop24h 59m

Knoxville McGhee Tyson

Mon 11/23

7:11 pm-5:26 pm

1 stop23h 15m

$309

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Wed 12/9

10:18 am-3:13 pm

1 stop3h 55m

Knoxville McGhee Tyson

Tue 12/15

8:30 am-11:48 am

1 stop4h 18m

$317

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Mon 11/23

12:42 pm-8:09 pm

1 stop6h 27m

Knoxville McGhee Tyson

Tue 12/29

6:00 am-9:24 am

1 stop4h 24m

$317

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Milwaukee to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Milwaukee and Knoxville?

Prices are currently typical for flights on this route.

Typical prices usually range from $286 to $481.
The lowest price recently found on this route was $303.

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Milwaukee, with most prices found around $242. If you aren’t able to travel during the month of January, then book flights to Knoxville from Milwaukee during August instead. Flights to Knoxville in August, while not as cheap as those in January, still average around $274.

How have Milwaukee to Knoxville flight prices changed over time?

As of October 2026, prices for Milwaukee to Knoxville flights are approximately 43% cheaper when compared to flights at the same time last year.

When to book flights from Milwaukee to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Knoxville (MKE to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Knoxville

Best Price Found

$152

Fastest flight time

4h 06m

Direct flights

None
The best one-way flight to Knoxville from Milwaukee in the past 72 hours is $152. The best round-trip flight deal from Milwaukee to Knoxville found on momondo in the last 72 hours is $303.
The fastest flight from Milwaukee to Knoxville takes 4h 06m
There are no direct flights from Milwaukee to Knoxville. There are no popular flight routes from Milwaukee to Knoxville.
Search flight deals

Frequently asked questions about flying from Milwaukee to Knoxville

  • How far is Milwaukee-Mitchell to Knoxville McGhee Tyson by plane?

    The distance between Milwaukee-Mitchell and Knoxville McGhee Tyson is about 532.7 mi. Flights usually cover this in 4h 06m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Milwaukee to Knoxville?

Best airlines flying from Milwaukee to Knoxville

Compare and see reviews for airlines that fly from Milwaukee to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $208Free CancellationRating
7.4
10,366 reviews
Search United Airlines flights
DeltaPriceFrom $208Free CancellationRating
7.8
8,652 reviews
Search Delta flights
American AirlinesPriceFrom $233Free CancellationRating
7.0
12,169 reviews
Search American Airlines flights
SouthwestPriceFrom $260Free CancellationRating
7.9
4,217 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Crossville
Maryville
Murphy
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Rockford
Jefferson City

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Milwaukee to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Milwaukee to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Knoxville?

Once you have performed a search for Milwaukee to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Milwaukee to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Milwaukee are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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