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Cheap flights from Milwaukee to Knoxville from $144

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Milwaukee to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:00 am - 9:45 amMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
3h 45m1 stop Chicago O'Hare Intl
United Airlines Logo
10:42 am - 1:43 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
4h 01m1 stop Chicago O'Hare Intl
$287United Airlines
Sat, Oct 10 - Sat, Oct 17
United Airlines Logo
5:00 am - 9:45 amMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
3h 45m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 10:07 amTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
5h 07m1 stop Chicago O'Hare Intl
$287United Airlines
Sat, Oct 10 - Sat, Oct 17
Delta Logo
12:36 pm - 5:28 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
3h 52m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:23 pm - 11:53 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
6h 30m1 stop Atlanta Hartsfield-Jackson
$287Delta
Wed, Oct 14 - Sat, Oct 17
Delta Logo
6:41 pm - 11:57 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
4h 16m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:09 pm - 11:54 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
6h 45m1 stop Atlanta Hartsfield-Jackson
$287Delta
Mon, Nov 9 - Wed, Nov 18
American Airlines Logo
2:48 pm - 10:42 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
6h 54m1 stop Chicago O'Hare Intl
American Airlines Logo
6:16 pm - 9:54 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
4h 38m1 stop Washington, D.C. Reagan-National
$287American Airlines
Wed, Sep 16 - Tue, Sep 22
American Airlines Logo
5:53 pm - 10:50 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
3h 57m1 stop Charlotte Douglas
American Airlines Logo
8:00 am - 12:48 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
5h 48m1 stop Chicago O'Hare Intl
$287American Airlines
Mon, Sep 14 - Thu, Sep 17
United Airlines Logo
5:00 am - 9:45 amMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
3h 45m1 stop Chicago O'Hare Intl
United Airlines Logo
5:40 pm - 10:15 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
5h 35m1 stop Chicago O'Hare Intl
$287United Airlines
Sat, Oct 24 - Tue, Oct 27
Southwest Logo
6:10 am - 12:20 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
5h 10m2 stops Chicago Midway Nashville Intl
Southwest Logo
7:25 pm - 12:15 amTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
5h 50m1 stop Nashville Intl
$292Southwest
Tue, Oct 27 - Thu, Oct 29
Southwest Logo
12:45 pm - 9:40 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
7h 55m1 stop Baltimore/Washington
Southwest Logo
1:00 pm - 9:20 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
9h 20m2 stops Orlando Baltimore/Washington
$298Southwest
Mon, Nov 9 - Wed, Nov 18
Multiple Airlines Logo
10:15 am - 11:36 pmMKE  Milwaukee-Mitchell-TYS Knoxville McGhee Tyson
12h 21m1 stop Orlando
Multiple Airlines Logo
1:37 pm - 7:15 pmTYS  Knoxville McGhee Tyson-MKE Milwaukee-Mitchell
30h 38m2 stops Washington, D.C. Dulles Intl Orlando
$616Multiple Airlines
Thu, Oct 15 - Sun, Oct 18

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Southwest flights from Milwaukee to Knoxville

Our best Southwest deals on Milwaukee to Knoxville flight tickets
Southwest
Oct 27
MKE6:10 amMilwaukee-Mitchell
5h 10m
2 stops
TYS12:20 pmKnoxville McGhee Tyson
Oct 29
TYS7:25 pmKnoxville McGhee Tyson
5h 50m
1 stop
MKE12:15 amMilwaukee-Mitchell
$292
Southwest
Sep 22
MKE8:20 amMilwaukee-Mitchell
10h 35m
2 stops
TYS7:55 pmKnoxville McGhee Tyson
Sep 26
TYS8:50 amKnoxville McGhee Tyson
7h 20m
1 stop
MKE3:10 pmMilwaukee-Mitchell
$298
Southwest
Oct 30
MKE12:20 pmMilwaukee-Mitchell
8h 10m
1 stop
TYS9:30 pmKnoxville McGhee Tyson
Nov 4
TYS1:00 pmKnoxville McGhee Tyson
9h 20m
2 stops
MKE9:20 pmMilwaukee-Mitchell
$311

United Airlines flights from Milwaukee to Knoxville

Our best United Airlines deals on Milwaukee to Knoxville flight tickets
United Airlines
Sep 13
MKE5:00 amMilwaukee-Mitchell
3h 54m
1 stop
TYS9:54 amKnoxville McGhee Tyson
Sep 20
TYS6:00 amKnoxville McGhee Tyson
5h 00m
1 stop
MKE10:00 amMilwaukee-Mitchell
$319
United Airlines
Sep 1
MKE6:15 amMilwaukee-Mitchell
6h 02m
1 stop
TYS1:17 pmKnoxville McGhee Tyson
Sep 5
TYS7:00 amKnoxville McGhee Tyson
4h 00m
1 stop
MKE10:00 amMilwaukee-Mitchell
$320
United Airlines
Sep 3
MKE10:19 amMilwaukee-Mitchell
5h 39m
1 stop
TYS4:58 pmKnoxville McGhee Tyson
Sep 7
TYS7:00 amKnoxville McGhee Tyson
4h 00m
1 stop
MKE10:00 amMilwaukee-Mitchell
$338

momondo Fare Finder

 
Use the filters below to find and compare flights from Milwaukee to Knoxville that are best for you.

Fly from

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Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Sat 10/10

5:00 am-9:45 am

1 stop3h 45m

Knoxville McGhee Tyson

Sat 10/17

10:42 am-1:43 pm

1 stop4h 01m

$287

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Sat 10/10

5:00 am-9:45 am

1 stop3h 45m

Knoxville McGhee Tyson

Sat 10/17

6:00 am-10:07 am

1 stop5h 07m

$287

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Wed 10/14

12:36 pm-5:28 pm

1 stop3h 52m

Knoxville McGhee Tyson

Sat 10/17

6:23 pm-11:53 pm

1 stop6h 30m

$287

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Mon 11/9

6:41 pm-11:57 pm

1 stop4h 16m

Knoxville McGhee Tyson

Wed 11/18

6:09 pm-11:54 pm

1 stop6h 45m

$287

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Wed 9/16

2:48 pm-10:42 pm

1 stop6h 54m

Knoxville McGhee Tyson

Tue 9/22

6:16 pm-9:54 pm

1 stop4h 38m

$287

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Mon 9/14

5:53 pm-10:50 pm

1 stop3h 57m

Knoxville McGhee Tyson

Thu 9/17

8:00 am-12:48 pm

1 stop5h 48m

$287

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Sat 10/24

5:00 am-9:45 am

1 stop3h 45m

Knoxville McGhee Tyson

Tue 10/27

5:40 pm-10:15 pm

1 stop5h 35m

$287

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Tue 10/27

6:10 am-12:20 pm

2 stops5h 10m

Knoxville McGhee Tyson

Thu 10/29

7:25 pm-12:15 am

1 stop5h 50m

$292

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Mon 11/9

12:45 pm-9:40 pm

1 stop7h 55m

Knoxville McGhee Tyson

Wed 11/18

1:00 pm-9:20 pm

2 stops9h 20m

$298

MilwaukeeKnoxville

MKE Milwaukee-Mitchell - TYS Knoxville McGhee Tyson

MKETYS

Milwaukee-Mitchell

Thu 10/15

10:15 am-11:36 pm

1 stop12h 21m

Knoxville McGhee Tyson

Sun 10/18

1:37 pm-7:15 pm

2 stops30h 38m

$616

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Milwaukee to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Milwaukee and Knoxville?

Prices are currently typical for flights on this route.

Typical prices usually range from $238 to $324.
The lowest price recently found on this route was $287.

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Milwaukee, with most prices found around $242. If you aren’t able to travel during the month of January, then book flights to Knoxville from Milwaukee during August instead. Flights to Knoxville in August, while not as cheap as those in January, still average around $274.

How far in advance should I book a flight from Milwaukee to Knoxville?

You are more likely to see cheaper flights to Knoxville from Milwaukee when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $333 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Milwaukee for as low as $208 on momondo.

How have Milwaukee to Knoxville flight prices changed over time?

As of August 2026, prices for Milwaukee to Knoxville flights are approximately 47% more expensive when compared to flights at the same time last year.

When to book flights from Milwaukee to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Knoxville (MKE to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Knoxville

Best Price Found

$144

Fastest flight time

3h 52m

Direct flights

None
The best one-way flight to Knoxville from Milwaukee in the past 72 hours is $144. The best round-trip flight deal from Milwaukee to Knoxville found on momondo in the last 72 hours is $287.
The fastest flight from Milwaukee to Knoxville takes 3h 52m
There are no direct flights from Milwaukee to Knoxville. There are no popular flight routes from Milwaukee to Knoxville.
Search flight deals

Frequently asked questions about flying from Milwaukee to Knoxville

  • How far is Milwaukee-Mitchell to Knoxville McGhee Tyson by plane?

    The distance between Milwaukee-Mitchell and Knoxville McGhee Tyson is about 532.7 mi. Flights usually cover this in 3h 52m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Milwaukee to Knoxville?

Best airlines flying from Milwaukee to Knoxville

Compare and see reviews for airlines that fly from Milwaukee to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $208Free CancellationRating
7.4
10,102 reviews
Search United Airlines flights
DeltaPriceFrom $208Free CancellationRating
7.8
8,505 reviews
Search Delta flights
American AirlinesPriceFrom $233Free CancellationRating
7.1
11,968 reviews
Search American Airlines flights
SouthwestPriceFrom $260Free CancellationRating
8.0
4,215 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Alcoa
Corbin
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Milwaukee to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Milwaukee to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Knoxville?

Once you have performed a search for Milwaukee to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Milwaukee to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Milwaukee are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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