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Cheap flights from Medford to Des Moines from $330

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to Des Moines departing on 8/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Medford to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:17 pm - 1:34 pm
MFR
-
DSM
38h 17m
2 stops
Multiple Airlines Logo
9:50 pm - 9:33 am
DSM
-
MFR
13h 43m
1 stop
$330Multiple Airlines
Mon, Aug 10 - Sun, Aug 23
Allegiant Air Logo
9:38 pm - 9:16 pm
MFR
-
DSM
21h 38m
1 stop
Allegiant Air Logo
9:50 pm - 9:33 am
DSM
-
MFR
13h 43m
1 stop
$332Allegiant Air
Thu, Aug 13 - Sun, Aug 23
Allegiant Air Logo
9:38 pm - 9:16 pm
MFR
-
DSM
21h 38m
1 stop
Allegiant Air Logo
9:50 pm - 9:33 am
DSM
-
MFR
13h 43m
1 stop
$343Allegiant Air
Thu, Aug 13 - Sun, Aug 23
Multiple Airlines Logo
9:17 pm - 1:34 pm
MFR
-
DSM
38h 17m
2 stops
Multiple Airlines Logo
9:50 pm - 10:18 am
DSM
-
MFR
14h 28m
1 stop
$346Multiple Airlines
Mon, Aug 10 - Thu, Aug 20
Allegiant Air Logo
9:38 pm - 9:16 pm
MFR
-
DSM
21h 38m
1 stop
Allegiant Air Logo
9:50 pm - 10:18 am
DSM
-
MFR
14h 28m
1 stop
$347Allegiant Air
Thu, Aug 13 - Thu, Aug 20
Multiple Airlines Logo
9:38 pm - 11:14 pm
MFR
-
DSM
23h 36m
2 stops
Multiple Airlines Logo
9:50 pm - 9:33 am
DSM
-
MFR
13h 43m
1 stop
$349Multiple Airlines
Sun, Aug 9 - Sun, Aug 23
Multiple Airlines Logo
9:38 pm - 11:14 pm
MFR
-
DSM
23h 36m
2 stops
Multiple Airlines Logo
9:50 pm - 9:33 am
DSM
-
MFR
13h 43m
1 stop
$353Multiple Airlines
Sun, Aug 9 - Sun, Aug 23
Multiple Airlines Logo
9:38 pm - 11:14 pm
MFR
-
DSM
23h 36m
2 stops
Multiple Airlines Logo
9:44 pm - 2:48 pm
DSM
-
MFR
19h 04m
1 stop
$360Multiple Airlines
Sun, Aug 9 - Thu, Aug 13
Multiple Airlines Logo
9:38 pm - 11:14 pm
MFR
-
DSM
23h 36m
2 stops
Multiple Airlines Logo
9:50 pm - 10:18 am
DSM
-
MFR
14h 28m
1 stop
$368Multiple Airlines
Sun, Aug 9 - Thu, Aug 20
Multiple Airlines Logo
9:38 pm - 11:14 pm
MFR
-
DSM
23h 36m
2 stops
Multiple Airlines Logo
9:50 pm - 9:33 am
DSM
-
MFR
13h 43m
1 stop
$370Multiple Airlines
Thu, Aug 13 - Sun, Aug 23

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Allegiant Air flights from Medford to Des Moines

Our best Allegiant Air deals on Medford to Des Moines flight tickets
Allegiant Air
Aug 13
MFR9:38 pmMedford
21h 38m
1 stop
DSM9:16 pmDes Moines
Aug 23
DSM9:50 pmDes Moines
13h 43m
1 stop
MFR9:33 amMedford
$332
Allegiant Air
Aug 13
MFR9:38 pmMedford
21h 38m
1 stop
DSM9:16 pmDes Moines
Aug 23
DSM9:50 pmDes Moines
13h 43m
1 stop
MFR9:33 amMedford
$343
Allegiant Air
Aug 13
MFR9:38 pmMedford
21h 38m
1 stop
DSM9:16 pmDes Moines
Aug 20
DSM9:50 pmDes Moines
14h 28m
1 stop
MFR10:18 amMedford
$347

Delta flights from Medford to Des Moines

Our best Delta deals on Medford to Des Moines flight tickets
Delta
Aug 13
MFR6:15 amMedford
26h 03m
2 stops
DSM10:18 amDes Moines
Aug 18
DSM2:45 pmDes Moines
11h 10m
2 stops
MFR11:55 pmMedford
$475
Delta
Aug 13
MFR5:28 pmMedford
14h 50m
2 stops
DSM10:18 amDes Moines
Aug 19
DSM5:56 pmDes Moines
7h 59m
2 stops
MFR11:55 pmMedford
$501
Delta
Aug 14
MFR5:28 pmMedford
14h 02m
2 stops
DSM9:30 amDes Moines
Aug 18
DSM2:45 pmDes Moines
11h 10m
2 stops
MFR11:55 pmMedford
$512

momondo Fare Finder

 
Customize your flight search to find flights from Medford to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Medford to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Mon 8/10

9:17 pm-1:34 pm

2 stops38h 17m

Des Moines

Sun 8/23

9:50 pm-9:33 am

1 stop13h 43m

$330
Quickest round-trip

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Thu 8/13

9:38 pm-9:16 pm

1 stop21h 38m

Des Moines

Sun 8/23

9:50 pm-9:33 am

1 stop13h 43m

$332

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Thu 8/13

9:38 pm-9:16 pm

1 stop21h 38m

Des Moines

Sun 8/23

9:50 pm-9:33 am

1 stop13h 43m

$343

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Mon 8/10

9:17 pm-1:34 pm

2 stops38h 17m

Des Moines

Thu 8/20

9:50 pm-10:18 am

1 stop14h 28m

$346

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Thu 8/13

9:38 pm-9:16 pm

1 stop21h 38m

Des Moines

Thu 8/20

9:50 pm-10:18 am

1 stop14h 28m

$347

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Sun 8/9

9:38 pm-11:14 pm

2 stops23h 36m

Des Moines

Sun 8/23

9:50 pm-9:33 am

1 stop13h 43m

$349

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Sun 8/9

9:38 pm-11:14 pm

2 stops23h 36m

Des Moines

Sun 8/23

9:50 pm-9:33 am

1 stop13h 43m

$353

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Sun 8/9

9:38 pm-11:14 pm

2 stops23h 36m

Des Moines

Thu 8/13

9:44 pm-2:48 pm

1 stop19h 04m

$360

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Sun 8/9

9:38 pm-11:14 pm

2 stops23h 36m

Des Moines

Thu 8/20

9:50 pm-10:18 am

1 stop14h 28m

$368

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Thu 8/13

9:38 pm-11:14 pm

2 stops23h 36m

Des Moines

Sun 8/23

9:50 pm-9:33 am

1 stop13h 43m

$370

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Medford to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to Des Moines (MFR to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to Des Moines

Fastest flight time

5h 31m

Direct flights

None
The fastest flight from Medford to Des Moines takes 5h 31m
There are no direct flights from Medford to Des Moines. There are no popular flight routes from Medford to Des Moines.
Search flight deals

Frequently asked questions about flying from Medford to Des Moines

  • How far is Medford to Des Moines by plane?

    A flight from Medford to Des Moines will travel around 1495.2 mi. A reasonable flight in good conditions will take 5h 31m.

  • When did momondo last update prices for flights from Medford Airport to Des Moines Airport?

    Prices for flights from Medford Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Medford Airport to Des Moines Airport?

  • How old do you have to be to fly from Medford Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Medford Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Medford to Des Moines?

Best airlines flying from Medford to Des Moines

Compare and see reviews for airlines that fly from Medford to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $368Free CancellationRating
7.4
9,926 reviews
Search United Airlines flights

Frequently asked questions about flying from Medford to Des Moines

  • How do I get Price Alerts for flights from Medford to Des Moines?

    Confirm your travel details to search for the latest offers for flights from Medford to Des Moines. While browsing offers there will be the option to toggle “Price Alerts”. You’ll then receive updates when prices for the flight route increase or decrease.

  • How can I save money on flights from Medford to Des Moines with momondo?

    With “Price Forecast”, learn how soon you should book your flight in advance. Down to the day of week and time of day, our information can inform you on the ideal time to book to save on your travel. Our “Price Calendar” shows you at a quick glance when to book your travel for lower rates. By setting “Price Alerts” you can monitor changes in price and target the ideal time to book. Search for your trip destination by budget amount via our “Explore” feature. Whether you’re looking for ideas for your next travel adventure or cost-cutting tips, our “Discover” content is a great place to start.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Medford to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Medford to Des Moines for you.

Can I find flights from Medford to Des Moines with flexible booking policies on momondo?

All flight searches from Medford to Des Moines on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Medford to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Medford to Des Moines.

I’m not ready to book a flight from Medford to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Medford and alert you when they change.

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