Cheap flights from Maryland to St. Louis from $64

In general, September is the cheapest month to fly from Maryland to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $75. The month of February is another great option to travel to St. Louis, with average flight prices from Maryland averaging around $104.

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $343. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $440. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Maryland at noon is the least expensive time of day to depart. momondo users have found prices as low as $358 when looking at flights departing at noon. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $408 per ticket.

Fly from Baltimore/Washington to Lambert-St Louis for the best Maryland - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Maryland when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $442 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Maryland for as low as $312 on momondo.

There is only 1 cabin class available to choose from on Maryland to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, Delta, and Southwest are the most popular carriers operating from Maryland to Lambert-St Louis

Southwest, Frontier and American Airlines are the top three most popular airlines that fly to St. Louis from Maryland according to our data. Southwest is the first choice among our users, with 46% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 4 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

As of July 2026, there are 22 flights per day flying from Maryland to St. Louis. The most common time of day flights depart is 6:00AM, with 43% of flights taking off in the evening.

As of July 2026, there are 154 flights per week flying from Maryland to St. Louis. The most common day of the week flights depart is Thu, with 19% of flights taking off on this day.