Cheap flights from Maryland to St. Louis from $69

In general, August is the cheapest month to fly from Maryland to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $275. The month of October is another great option to travel to St. Louis, with average flight prices from Maryland averaging around $293.

The cheapest day to depart on your flight to St. Louis is on a Tuesday when prices can be found for as low as $329. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $405. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Maryland in the evening is the least expensive time of day to depart. momondo users have found prices as low as $318 when looking at flights departing in the evening. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $387 per ticket.

Fly from Baltimore/Washington to Lambert-St Louis for the best Maryland - Lambert-St Louis flight prices

There is only 1 cabin class available to choose from on Maryland to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 3% on your flight if you consider stops on a Maryland to St. Louis flight.

Frontier, Southwest, and Delta are the most popular carriers operating from Maryland to Lambert-St Louis

Southwest, Frontier and American Airlines are the top three most popular airlines that fly to St. Louis from Maryland according to our data. Southwest is the first choice among our users, with 50% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 4 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

As of March 2026, there are 17 flights per day flying from Maryland to St. Louis. The most common time of day flights depart is 6:00AM, with 43% of flights taking off at noon.

As of March 2026, there are 120 flights per week flying from Maryland to St. Louis. The most common day of the week flights depart is Fri, with 22% of flights taking off on this day.