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Cheap flights from Manchester, New Hampshire to South America from $321

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to South America departing on 2/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Manchester, New Hampshire to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:26 pm - 10:05 pm
MHT
-
MDE
26h 39m2 stops
United Airlines Logo
10:45 am - 6:51 pm
MDE
-
MHT
32h 06m2 stops
$321United Airlines
Sun, Feb 1 - Thu, Feb 5
United Airlines Logo
7:26 pm - 10:05 pm
MHT
-
MDE
26h 39m2 stops
United Airlines Logo
10:45 am - 6:51 pm
MDE
-
MHT
32h 06m2 stops
$365United Airlines
Sun, Feb 1 - Thu, Feb 5
United Airlines Logo
2:17 pm - 5:10 am
MHT
-
BOG
14h 53m2 stops
United Airlines Logo
1:30 am - 6:51 pm
BOG
-
MHT
17h 21m2 stops
$500United Airlines
Mon, Feb 2 - Wed, Feb 4
American Airlines Logo
1:48 pm - 1:30 pm
MHT
-
CTG
23h 42m2 stops
American Airlines Logo
4:30 pm - 1:17 pm
CTG
-
MHT
20h 47m2 stops
$514American Airlines
Fri, Jan 16 - Wed, Jan 21
American Airlines Logo
4:06 pm - 1:30 pm
MHT
-
CTG
21h 24m2 stops
American Airlines Logo
4:30 pm - 11:17 am
CTG
-
MHT
18h 47m2 stops
$596American Airlines
Thu, Jan 15 - Tue, Jan 20
American Airlines Logo
1:48 pm - 1:30 pm
MHT
-
CTG
23h 42m2 stops
American Airlines Logo
4:30 pm - 11:17 am
CTG
-
MHT
18h 47m2 stops
$601American Airlines
Fri, Jan 16 - Tue, Jan 20
American Airlines Logo
6:42 am - 1:30 pm
MHT
-
CTG
30h 48m2 stops
American Airlines Logo
4:30 pm - 1:17 pm
CTG
-
MHT
20h 47m2 stops
$605American Airlines
Wed, Jan 14 - Wed, Jan 21
American Airlines Logo
4:06 pm - 1:30 pm
MHT
-
CTG
21h 24m2 stops
American Airlines Logo
4:30 pm - 1:17 pm
CTG
-
MHT
20h 47m2 stops
$640American Airlines
Thu, Jan 15 - Wed, Jan 21
United Airlines Logo
7:26 pm - 5:35 pm
MHT
-
GYE
22h 09m2 stops
United Airlines Logo
12:20 pm - 6:51 pm
GYE
-
MHT
30h 31m2 stops
$909United Airlines
Mon, Feb 2 - Thu, Feb 5
Multiple Airlines Logo
7:00 am - 10:40 pm
MHT
-
GRU
37h 40m2 stops
Multiple Airlines Logo
7:35 am - 1:15 pm
GRU
-
MHT
55h 40m2 stops
$1,005Multiple Airlines
Tue, Feb 3 - Tue, Feb 10

United Airlines flights from Manchester, New Hampshire to South America

Our best United Airlines deals on Manchester, New Hampshire to South America flight tickets
United Airlines
Feb 1
MHT7:26 pmManchester
26h 39m
2 stops
MDE10:05 pmMedellín Jose Maria Cordova Intl
Feb 5
MDE10:45 amMedellín Jose Maria Cordova Intl
32h 06m
2 stops
MHT6:51 pmManchester
$321
Find similar
United Airlines
Feb 1
MHT7:26 pmManchester
26h 39m
2 stops
MDE10:05 pmMedellín Jose Maria Cordova Intl
Feb 5
MDE10:45 amMedellín Jose Maria Cordova Intl
32h 06m
2 stops
MHT6:51 pmManchester
$365
Find similar
United Airlines
Feb 2
MHT2:17 pmManchester
14h 53m
2 stops
BOG5:10 amBogotá El Dorado
Feb 4
BOG1:30 amBogotá El Dorado
17h 21m
2 stops
MHT6:51 pmManchester
$500
Find similar

American Airlines flights from Manchester, New Hampshire to South America

Our best American Airlines deals on Manchester, New Hampshire to South America flight tickets
American Airlines
Jan 16
MHT1:48 pmManchester
23h 42m
2 stops
CTG1:30 pmCartagena Rafael Nunez
Jan 21
CTG4:30 pmCartagena Rafael Nunez
20h 47m
2 stops
MHT1:17 pmManchester
$514
Find similar
American Airlines
Jan 15
MHT4:06 pmManchester
21h 24m
2 stops
CTG1:30 pmCartagena Rafael Nunez
Jan 20
CTG4:30 pmCartagena Rafael Nunez
18h 47m
2 stops
MHT11:17 amManchester
$596
Find similar
American Airlines
Jan 16
MHT1:48 pmManchester
23h 42m
2 stops
CTG1:30 pmCartagena Rafael Nunez
Jan 20
CTG4:30 pmCartagena Rafael Nunez
18h 47m
2 stops
MHT11:17 amManchester
$601
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterMedellín

MHT - MDE

MHTMDE

Manchester

Sun 2/1

7:26 pm-10:05 pm

2 stops26h 39m

Medellín Jose Maria Cordova Intl

Thu 2/5

10:45 am-6:51 pm

2 stops32h 06m

$321

ManchesterMedellín

MHT - MDE

MHTMDE

Manchester

Sun 2/1

7:26 pm-10:05 pm

2 stops26h 39m

Medellín Jose Maria Cordova Intl

Thu 2/5

10:45 am-6:51 pm

2 stops32h 06m

$365

ManchesterBogotá

MHT - BOG

MHTBOG

Manchester

Mon 2/2

2:17 pm-5:10 am

2 stops14h 53m

Bogotá El Dorado

Wed 2/4

1:30 am-6:51 pm

2 stops17h 21m

$500

ManchesterCartagena

MHT - CTG

MHTCTG

Manchester

Fri 1/16

1:48 pm-1:30 pm

2 stops23h 42m

Cartagena Rafael Nunez

Wed 1/21

4:30 pm-1:17 pm

2 stops20h 47m

$514

ManchesterCartagena

MHT - CTG

MHTCTG

Manchester

Thu 1/15

4:06 pm-1:30 pm

2 stops21h 24m

Cartagena Rafael Nunez

Tue 1/20

4:30 pm-11:17 am

2 stops18h 47m

$596

ManchesterCartagena

MHT - CTG

MHTCTG

Manchester

Fri 1/16

1:48 pm-1:30 pm

2 stops23h 42m

Cartagena Rafael Nunez

Tue 1/20

4:30 pm-11:17 am

2 stops18h 47m

$601

ManchesterCartagena

MHT - CTG

MHTCTG

Manchester

Wed 1/14

6:42 am-1:30 pm

2 stops30h 48m

Cartagena Rafael Nunez

Wed 1/21

4:30 pm-1:17 pm

2 stops20h 47m

$605

ManchesterCartagena

MHT - CTG

MHTCTG

Manchester

Thu 1/15

4:06 pm-1:30 pm

2 stops21h 24m

Cartagena Rafael Nunez

Wed 1/21

4:30 pm-1:17 pm

2 stops20h 47m

$640

ManchesterGuayaquil

MHT - GYE

MHTGYE

Manchester

Mon 2/2

7:26 pm-5:35 pm

2 stops22h 09m

Guayaquil Jose Joaquin de Olmedo

Thu 2/5

12:20 pm-6:51 pm

2 stops30h 31m

$909

ManchesterSao Paulo

MHT - GRU

MHTGRU

Manchester

Tue 2/3

7:00 am-10:40 pm

2 stops37h 40m

Sao Paulo Guarulhos Intl

Tue 2/10

7:35 am-1:15 pm

2 stops55h 40m

$1,005

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Manchester, New Hampshire to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Manchester, New Hampshire to South America is on a Tuesday when prices can be found for as low as $802. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Manchester, New Hampshire to South America for around $1,041.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Manchester, New Hampshire to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $796. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $895 on average. Flights to South America from Manchester, New Hampshire in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Manchester, New Hampshire to South America flights?

You could potentially save up to 7% on your flight if you consider stops on a Manchester, New Hampshire to South America flight.

Cheap Manchester, New Hampshire to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to South America

Fastest flight time

11h 39m

Direct flights

None
The fastest flight from Manchester, New Hampshire to South America takes 11h 39m
There are no direct flights from Manchester, New Hampshire to South America. There are no popular flight routes from Manchester, New Hampshire to South America.
Search flight deals

  • When did momondo last update prices for flights from Manchester Airport to South America?

    Prices for flights from Manchester Airport to South America were last updated today.

  • How old do you have to be to fly from Manchester Airport to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Manchester Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to South America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Manchester to South America. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Manchester to South America with flexible booking policies on momondo?

All flight searches from Manchester to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Manchester to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to South America.

I’m not ready to book a flight from Manchester to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Manchester to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Wed 1/21
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Find better results for your trip to South America

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