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Cheap flights from Madison to Knoxville from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madison to Knoxville departing on 4/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Madison to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:18 pm - 9:21 pm
MSN
-
TYS
6h 03m
1 stop
American Airlines Logo
6:00 am - 11:14 am
TYS
-
MSN
6h 14m
1 stop
$300American Airlines
Wed, May 6 - Sun, May 10
American Airlines Logo
5:08 pm - 10:24 pm
MSN
-
TYS
4h 16m
1 stop
American Airlines Logo
8:48 pm - 11:38 pm
TYS
-
MSN
3h 50m
1 stop
$309American Airlines
Fri, Apr 10 - Fri, Apr 17
American Airlines Logo
5:17 pm - 11:50 pm
MSN
-
TYS
5h 33m
1 stop
American Airlines Logo
6:38 pm - 11:28 pm
TYS
-
MSN
5h 50m
1 stop
$329American Airlines
Mon, Apr 6 - Mon, Apr 13
American Airlines Logo
5:17 pm - 11:50 pm
MSN
-
TYS
5h 33m
1 stop
American Airlines Logo
6:38 pm - 11:28 pm
TYS
-
MSN
5h 50m
1 stop
$334American Airlines
Mon, Apr 6 - Mon, Apr 13
American Airlines Logo
2:18 pm - 9:21 pm
MSN
-
TYS
6h 03m
1 stop
American Airlines Logo
5:11 pm - 9:52 pm
TYS
-
MSN
5h 41m
1 stop
$359American Airlines
Mon, Apr 13 - Mon, Apr 20
American Airlines Logo
2:18 pm - 8:18 pm
MSN
-
TYS
5h 00m
1 stop
American Airlines Logo
6:38 pm - 11:28 pm
TYS
-
MSN
5h 50m
1 stop
$360American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
2:18 pm - 9:21 pm
MSN
-
TYS
6h 03m
1 stop
American Airlines Logo
5:11 pm - 9:52 pm
TYS
-
MSN
5h 41m
1 stop
$362American Airlines
Mon, Apr 13 - Mon, Apr 20
American Airlines Logo
6:20 am - 3:26 pm
MSN
-
TYS
8h 06m
1 stop
American Airlines Logo
6:00 am - 11:14 am
TYS
-
MSN
6h 14m
1 stop
$364American Airlines
Mon, May 11 - Fri, May 15
United Airlines Logo
5:55 pm - 10:34 pm
MSN
-
TYS
3h 39m
1 stop
United Airlines Logo
7:00 am - 10:11 am
TYS
-
MSN
4h 11m
1 stop
$369United Airlines
Mon, Apr 13 - Thu, Apr 16
United Airlines Logo
5:55 pm - 10:34 pm
MSN
-
TYS
3h 39m
1 stop
United Airlines Logo
5:53 pm - 9:21 pm
TYS
-
MSN
4h 28m
1 stop
$379United Airlines
Sat, Apr 4 - Wed, Apr 8

United Airlines flights from Madison to Knoxville

Our best United Airlines deals on Madison to Knoxville flight tickets
United Airlines
Apr 13
MSN5:55 pmMadison Truax Field
3h 39m
1 stop
TYS10:34 pmKnoxville McGhee Tyson
Apr 16
TYS7:00 amKnoxville McGhee Tyson
4h 11m
1 stop
MSN10:11 amMadison Truax Field
$369
United Airlines
Apr 4
MSN5:55 pmMadison Truax Field
3h 39m
1 stop
TYS10:34 pmKnoxville McGhee Tyson
Apr 8
TYS5:53 pmKnoxville McGhee Tyson
4h 28m
1 stop
MSN9:21 pmMadison Truax Field
$379
United Airlines
Apr 14
MSN5:00 amMadison Truax Field
4h 08m
1 stop
TYS10:08 amKnoxville McGhee Tyson
Apr 18
TYS7:00 amKnoxville McGhee Tyson
5h 38m
1 stop
MSN11:38 amMadison Truax Field
$381

American Airlines flights from Madison to Knoxville

Our best American Airlines deals on Madison to Knoxville flight tickets
American Airlines
May 6
MSN2:18 pmMadison Truax Field
6h 03m
1 stop
TYS9:21 pmKnoxville McGhee Tyson
May 10
TYS6:00 amKnoxville McGhee Tyson
6h 14m
1 stop
MSN11:14 amMadison Truax Field
$300
American Airlines
Apr 10
MSN5:08 pmMadison Truax Field
4h 16m
1 stop
TYS10:24 pmKnoxville McGhee Tyson
Apr 17
TYS8:48 pmKnoxville McGhee Tyson
3h 50m
1 stop
MSN11:38 pmMadison Truax Field
$309
American Airlines
Apr 6
MSN5:17 pmMadison Truax Field
5h 33m
1 stop
TYS11:50 pmKnoxville McGhee Tyson
Apr 13
TYS6:38 pmKnoxville McGhee Tyson
5h 50m
1 stop
MSN11:28 pmMadison Truax Field
$329

momondo Fare Finder

 
Customize your flight search to find flights from Madison to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Madison to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Wed 5/6

2:18 pm-9:21 pm

1 stop6h 03m

Knoxville McGhee Tyson

Sun 5/10

6:00 am-11:14 am

1 stop6h 14m

$300

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Fri 4/10

5:08 pm-10:24 pm

1 stop4h 16m

Knoxville McGhee Tyson

Fri 4/17

8:48 pm-11:38 pm

1 stop3h 50m

$309

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Mon 4/6

5:17 pm-11:50 pm

1 stop5h 33m

Knoxville McGhee Tyson

Mon 4/13

6:38 pm-11:28 pm

1 stop5h 50m

$329

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Mon 4/6

5:17 pm-11:50 pm

1 stop5h 33m

Knoxville McGhee Tyson

Mon 4/13

6:38 pm-11:28 pm

1 stop5h 50m

$334

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Mon 4/13

2:18 pm-9:21 pm

1 stop6h 03m

Knoxville McGhee Tyson

Mon 4/20

5:11 pm-9:52 pm

1 stop5h 41m

$359

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Thu 4/9

2:18 pm-8:18 pm

1 stop5h 00m

Knoxville McGhee Tyson

Mon 4/13

6:38 pm-11:28 pm

1 stop5h 50m

$360

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Mon 4/13

2:18 pm-9:21 pm

1 stop6h 03m

Knoxville McGhee Tyson

Mon 4/20

5:11 pm-9:52 pm

1 stop5h 41m

$362

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Mon 5/11

6:20 am-3:26 pm

1 stop8h 06m

Knoxville McGhee Tyson

Fri 5/15

6:00 am-11:14 am

1 stop6h 14m

$364
Quickest round-trip

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Mon 4/13

5:55 pm-10:34 pm

1 stop3h 39m

Knoxville McGhee Tyson

Thu 4/16

7:00 am-10:11 am

1 stop4h 11m

$369

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 4/4

5:55 pm-10:34 pm

1 stop3h 39m

Knoxville McGhee Tyson

Wed 4/8

5:53 pm-9:21 pm

1 stop4h 28m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Madison to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of October is, on average, the cheapest month to fly to Knoxville from Madison, with most prices found around $313. If you aren’t able to travel during the month of October, then book flights to Knoxville from Madison during December instead. Flights to Knoxville in December, while not as cheap as those in October, still average around $317.

When to book flights from Madison to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Madison to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Madison to Knoxville (MSN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madison to Knoxville

Fastest flight time

3h 39m

Direct flights

None
The fastest flight from Madison to Knoxville takes 3h 39m
There are no direct flights from Madison to Knoxville. There are no popular flight routes from Madison to Knoxville.
Search flight deals

  • How far is Madison Truax Field to Knoxville McGhee Tyson by plane?

    There are 571.0 mi between Madison Truax Field and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 3h 39m.

  • When did momondo last update prices for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madison Truax Field Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Madison to Knoxville?

Best airlines flying from Madison to Knoxville

Compare and see reviews for airlines that fly from Madison to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Jefferson City
Dandridge
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Madison to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Madison to Knoxville for you.

Can I find flights from Madison to Knoxville with flexible booking policies on momondo?

Flights from Madison to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Madison to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Madison to Knoxville.

I’m not ready to book a flight from Madison to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Madison to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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