What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Madison according to our data. American Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Madison Truax Field to Knoxville McGhee Tyson?

United Airlines and American Airlines are the most popular carriers operating from Madison Truax Field to Knoxville McGhee Tyson

When did momondo last update prices for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport are updated daily.

How many operators does momondo search for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?

As of December 2025, there are 2 operators available to choose from for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madison Truax Field Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$189 Cheap Flights from Madison to Knoxville in 2025/26

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1:20 pm - 8:55 pm

MSN

TYS

6h 35m1 stop

5:30 am - 10:33 am

TYS

MSN

6h 03m1 stop

$269Delta

Tue, Mar 31 - Tue, Apr 7

3:33 pm - 11:47 pm

MSN

TYS

7h 14m1 stop

4:33 pm - 10:51 pm

TYS

MSN

7h 18m1 stop

$279American Airlines

Wed, May 6 - Sat, May 9

5:09 am - 11:59 am

MSN

TYS

5h 50m2 stops

5:56 am - 10:31 am

TYS

MSN

5h 35m1 stop

$313American Airlines

Wed, May 6 - Sat, May 9

6:30 am - 1:24 pm

MSN

TYS

5h 54m1 stop

11:10 am - 2:10 pm

TYS

MSN

4h 00m1 stop

$319United Airlines

Sat, Jan 31 - Wed, Feb 4

6:30 am - 1:24 pm

MSN

TYS

5h 54m1 stop

11:10 am - 2:10 pm

TYS

MSN

4h 00m1 stop

$321United Airlines

Sat, Jan 31 - Wed, Feb 4

8:15 am - 8:52 pm

MSN

TYS

11h 37m2 stops

11:10 am - 2:52 pm

TYS

MSN

4h 42m1 stop

$324United Airlines

Sat, Jan 31 - Wed, Feb 4

6:30 am - 1:24 pm

MSN

TYS

5h 54m1 stop

11:10 am - 9:20 pm

TYS

MSN

11h 10m2 stops

$326United Airlines

Sat, Jan 31 - Wed, Feb 4

8:15 am - 8:52 pm

MSN

TYS

11h 37m2 stops

11:10 am - 9:20 pm

TYS

MSN

11h 10m2 stops

$329United Airlines

Sat, Jan 31 - Wed, Feb 4

8:15 am - 8:52 pm

MSN

TYS

11h 37m2 stops

2:25 pm - 11:44 pm

TYS

MSN

10h 19m2 stops

$331United Airlines

Sat, Jan 31 - Wed, Feb 4

1:20 pm - 8:55 pm

MSN

TYS

6h 35m1 stop

5:30 am - 10:33 am

TYS

MSN

6h 03m1 stop

$377Delta

Tue, Mar 31 - Wed, Apr 1

Delta flights from Madison to Knoxville

Our best Delta deals on Madison to Knoxville flight tickets

Delta

Mar 31

MSN1:20 pmMadison Truax Field

6h 35m

1 stop

TYS8:55 pmKnoxville McGhee Tyson

Apr 7

TYS5:30 amKnoxville McGhee Tyson

6h 03m

1 stop

MSN10:33 amMadison Truax Field

$269

Find similar

Delta

Mar 31

MSN1:20 pmMadison Truax Field

6h 35m

1 stop

TYS8:55 pmKnoxville McGhee Tyson

Apr 1

TYS5:30 amKnoxville McGhee Tyson

6h 03m

1 stop

MSN10:33 amMadison Truax Field

$377

Find similar

Delta

Mar 27

MSN7:00 amMadison Truax Field

12h 55m

1 stop

TYS8:55 pmKnoxville McGhee Tyson

Apr 7

TYS5:30 amKnoxville McGhee Tyson

6h 03m

1 stop

MSN10:33 amMadison Truax Field

$428

Find similar

American Airlines flights from Madison to Knoxville

Our best American Airlines deals on Madison to Knoxville flight tickets

American Airlines

May 6

MSN3:33 pmMadison Truax Field

7h 14m

1 stop

TYS11:47 pmKnoxville McGhee Tyson

May 9

TYS4:33 pmKnoxville McGhee Tyson

7h 18m

1 stop

MSN10:51 pmMadison Truax Field

$279

Find similar

American Airlines

May 6

MSN5:09 amMadison Truax Field

5h 50m

2 stops

TYS11:59 amKnoxville McGhee Tyson

May 9

TYS5:56 amKnoxville McGhee Tyson

5h 35m

1 stop

MSN10:31 amMadison Truax Field

$313

Find similar

American Airlines

Dec 12

MSN1:40 pmMadison Truax Field

6h 42m

2 stops

TYS9:22 pmKnoxville McGhee Tyson

Dec 15

TYS6:29 pmKnoxville McGhee Tyson

5h 52m

1 stop

MSN11:21 pmMadison Truax Field

$374

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Tue 3/31

1:20 pm-8:55 pm

1 stop6h 35m

Knoxville McGhee Tyson

Tue 4/7

5:30 am-10:33 am

1 stop6h 03m

$269

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Wed 5/6

3:33 pm-11:47 pm

1 stop7h 14m

Knoxville McGhee Tyson

Sat 5/9

4:33 pm-10:51 pm

1 stop7h 18m

$279

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Wed 5/6

5:09 am-11:59 am

2 stops5h 50m

Knoxville McGhee Tyson

Sat 5/9

5:56 am-10:31 am

1 stop5h 35m

$313

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 1/31

6:30 am-1:24 pm

1 stop5h 54m

Knoxville McGhee Tyson

Wed 2/4

11:10 am-2:10 pm

1 stop4h 00m

$319

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 1/31

6:30 am-1:24 pm

1 stop5h 54m

Knoxville McGhee Tyson

Wed 2/4

11:10 am-2:10 pm

1 stop4h 00m

$321

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 1/31

8:15 am-8:52 pm

2 stops11h 37m

Knoxville McGhee Tyson

Wed 2/4

11:10 am-2:52 pm

1 stop4h 42m

$324

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 1/31

6:30 am-1:24 pm

1 stop5h 54m

Knoxville McGhee Tyson

Wed 2/4

11:10 am-9:20 pm

2 stops11h 10m

$326

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 1/31

8:15 am-8:52 pm

2 stops11h 37m

Knoxville McGhee Tyson

Wed 2/4

11:10 am-9:20 pm

2 stops11h 10m

$329

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 1/31

8:15 am-8:52 pm

2 stops11h 37m

Knoxville McGhee Tyson

Wed 2/4

2:25 pm-11:44 pm

2 stops10h 19m

$331

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Tue 3/31

1:20 pm-8:55 pm

1 stop6h 35m

Knoxville McGhee Tyson

Wed 4/1

5:30 am-10:33 am

1 stop6h 03m

$377

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first

How to get the cheapest flight ticket from Madison to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Knoxville?

The month of December is, on average, the cheapest month to fly to Knoxville from Madison, with most prices found around $317. If you aren’t able to travel during the month of December, then book flights to Knoxville from Madison during October instead. Flights to Knoxville in October, while not as cheap as those in December, still average around $318.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Madison to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $343. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Madison to Knoxville for around $468.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Madison to Knoxville when you can find flight prices for as low as $363. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $410.

When to book flights from Madison to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Madison to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Madison to Knoxville (MSN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madison to Knoxville

Fastest flight time	3h 52m
Direct flights	None

The fastest flight from Madison to Knoxville takes 3h 52m

There are no direct flights from Madison to Knoxville. There are no popular flight routes from Madison to Knoxville.

Search flight deals

How far is Madison Truax Field to Knoxville McGhee Tyson by plane?
There are 571.0 mi between Madison Truax Field and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 3h 52m.
When did momondo last update prices for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport are updated daily.
How many operators does momondo search for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?
As of December 2025, there are 2 operators available to choose from for flights from Madison Truax Field Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Madison Truax Field Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madison Truax Field Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Madison to Knoxville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Madison to Knoxville is American Airlines (82% of total bookings). The next most popular airline is United Airlines (18%).

Best airlines flying from Madison to Knoxville

Compare and see reviews for airlines that fly from Madison to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,095 reviews		Search United Airlines flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,050 reviews		Search American Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Maryville

Crossville

Murphy

Alcoa

Oak Ridge

Lenoir City

Newport

Kodak

Dandridge

Jefferson City

Clinton

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Madison to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Madison to Knoxville for you.

Can I find flights from Madison to Knoxville with flexible booking policies on momondo?

Flights from Madison to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Madison to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Madison to Knoxville.

I’m not ready to book a flight from Madison to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Madison to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.