How many flights depart from Louisville to South Carolina on average per week?

The number of flights available between Louisville and South Carolina is 27 per week as of April 2026. The most frequent departure day is Wed, with 30% of weekly flights leaving on this day.

What is the cheapest airline that flies from Louisville Intl to South Carolina?

Allegiant Air, Breeze Airways, and United Airlines are the most popular carriers operating from Louisville Intl to South Carolina

What airlines fly to South Carolina?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to South Carolina from Louisville according to our data. Allegiant Air is the first choice among our users, with 40% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Louisville Intl Airport to South Carolina?

Prices for flights from Louisville Intl Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Louisville Intl Airport to South Carolina?

There are 7 operators available for flights from Louisville Intl Airport to South Carolina as of April 2026.

How old do you have to be to fly from Louisville Intl Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$54 Cheap Flights from Louisville to South Carolina in 2026

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Find the cheapest flights from Louisville to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:28 pm - 10:06 pm

SDF

CHS

1h 38mnonstop

7:00 am - 8:46 am

CHS

SDF

1h 46mnonstop

$103Breeze Airways

Mon, Aug 24 - Fri, Aug 28

11:29 am - 1:03 pm

SDF

SAV

1h 34mnonstop

6:16 pm - 7:55 pm

SAV

SDF

1h 39mnonstop

$104Allegiant Air

Sun, Aug 9 - Thu, Aug 13

1:06 pm - 2:38 pm

SDF

MYR

1h 32mnonstop

10:37 am - 12:12 pm

MYR

SDF

1h 35mnonstop

$113Allegiant Air

Sat, Jun 27 - Sat, Jul 4

6:06 pm - 11:29 pm

SDF

MYR

5h 23m

1 stop

11:52 am - 5:04 pm

MYR

SDF

5h 12m

1 stop

$220Spirit Airlines

Fri, May 1 - Sat, May 2

3:45 pm - 8:25 pm

SDF

SAV

4h 40m

1 stop

11:30 am - 2:45 pm

SAV

SDF

3h 15m

1 stop

$270Southwest

Wed, Apr 29 - Wed, May 6

7:08 am - 11:11 am

SDF

CAE

4h 03m

1 stop

5:38 am - 10:20 am

CAE

SDF

4h 42m

1 stop

$271Delta

Tue, May 12 - Sat, May 16

6:00 am - 10:29 am

SDF

SAV

4h 29m

1 stop

3:03 pm - 9:26 pm

SAV

SDF

6h 23m

1 stop

$275American Airlines

Tue, May 19 - Tue, May 19

1:18 pm - 5:55 pm

SDF

CAE

4h 37m

1 stop

4:12 pm - 9:28 pm

CAE

SDF

5h 16m

1 stop

$290American Airlines

Tue, Apr 28 - Sat, May 2

8:10 am - 1:14 pm

SDF

CAE

5h 04m

1 stop

4:01 pm - 8:39 pm

CAE

SDF

4h 38m

1 stop

$309Delta

Wed, Apr 22 - Sun, Apr 26

6:20 am - 1:10 pm

SDF

GSP

6h 50m

1 stop

6:30 am - 12:50 pm

GSP

SDF

6h 20m

1 stop

$329Southwest

Wed, May 27 - Sun, May 31

Delta flights from Louisville to South Carolina

Our best Delta deals on Louisville to South Carolina flight tickets

Delta

May 12

SDF7:08 amLouisville Intl

4h 03m

1 stop

CAE11:11 amColumbia Metropolitan

May 16

CAE5:38 amColumbia Metropolitan

4h 42m

1 stop

SDF10:20 amLouisville Intl

$271

Delta

May 2

SDF6:00 amLouisville Intl

3h 40m

1 stop

MYR9:40 amMyrtle Beach Intl

May 6

MYR10:26 amMyrtle Beach Intl

4h 05m

1 stop

SDF2:31 pmLouisville Intl

$303

Delta

Apr 22

SDF8:10 amLouisville Intl

5h 04m

1 stop

CAE1:14 pmColumbia Metropolitan

Apr 26

CAE4:01 pmColumbia Metropolitan

4h 38m

1 stop

SDF8:39 pmLouisville Intl

$309

Spirit Airlines flights from Louisville to South Carolina

Our best Spirit Airlines deals on Louisville to South Carolina flight tickets

Spirit Airlines

May 1

SDF6:06 pmLouisville Intl

5h 23m

1 stop

MYR11:29 pmMyrtle Beach Intl

May 2

MYR11:52 amMyrtle Beach Intl

5h 12m

1 stop

SDF5:04 pmLouisville Intl

$220

Spirit Airlines

Apr 16

SDF6:06 pmLouisville Intl

5h 23m

1 stop

MYR11:29 pmMyrtle Beach Intl

Apr 19

MYR11:52 amMyrtle Beach Intl

5h 12m

1 stop

SDF5:04 pmLouisville Intl

$285

Spirit Airlines

Apr 16

SDF6:06 pmLouisville Intl

5h 23m

1 stop

MYR11:29 pmMyrtle Beach Intl

Apr 20

MYR11:52 amMyrtle Beach Intl

5h 12m

1 stop

SDF5:04 pmLouisville Intl

$286

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Mon 8/24

8:28 pm-10:06 pm

Nonstop1h 38m

Charleston

Fri 8/28

7:00 am-8:46 am

Nonstop1h 46m

$103

LouisvilleSavannah

SDF - SAV

SDFSAV

Louisville Intl

Sun 8/9

11:29 am-1:03 pm

Nonstop1h 34m

Savannah/Hilton Head

Thu 8/13

6:16 pm-7:55 pm

Nonstop1h 39m

$104

Quickest round-trip

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Sat 6/27

1:06 pm-2:38 pm

Nonstop1h 32m

Myrtle Beach Intl

Sat 7/4

10:37 am-12:12 pm

Nonstop1h 35m

$113

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Fri 5/1

6:06 pm-11:29 pm

1 stop5h 23m

Myrtle Beach Intl

Sat 5/2

11:52 am-5:04 pm

1 stop5h 12m

$220

LouisvilleSavannah

SDF - SAV

SDFSAV

Louisville Intl

Wed 4/29

3:45 pm-8:25 pm

1 stop4h 40m

Savannah/Hilton Head

Wed 5/6

11:30 am-2:45 pm

1 stop3h 15m

$270

LouisvilleColumbia

SDF - CAE

SDFCAE

Louisville Intl

Tue 5/12

7:08 am-11:11 am

1 stop4h 03m

Columbia Metropolitan

Sat 5/16

5:38 am-10:20 am

1 stop4h 42m

$271

LouisvilleSavannah

SDF - SAV

SDFSAV

Louisville Intl

Tue 5/19

6:00 am-10:29 am

1 stop4h 29m

Savannah/Hilton Head

Tue 5/19

3:03 pm-9:26 pm

1 stop6h 23m

$275

LouisvilleColumbia

SDF - CAE

SDFCAE

Louisville Intl

Tue 4/28

1:18 pm-5:55 pm

1 stop4h 37m

Columbia Metropolitan

Sat 5/2

4:12 pm-9:28 pm

1 stop5h 16m

$290

LouisvilleColumbia

SDF - CAE

SDFCAE

Louisville Intl

Wed 4/22

8:10 am-1:14 pm

1 stop5h 04m

Columbia Metropolitan

Sun 4/26

4:01 pm-8:39 pm

1 stop4h 38m

$309

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Wed 5/27

6:20 am-1:10 pm

1 stop6h 50m

Greenville

Sun 5/31

6:30 am-12:50 pm

1 stop6h 20m

$329

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Louisville to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Louisville is in September. Flight prices, which tend to average around $156, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Louisville during August instead. Flights to South Carolina in August, while not as cheap as those in September, still average around $176.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Friday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $128. The most expensive day to fly to South Carolina is Wednesday, with ticket prices averaging around $204.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Louisville to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $130. Try not to purchase tickets at noon because they tend to be around $204. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Louisville Intl to South Carolina flight route?

Fly from Louisville Intl to Myrtle Beach Intl for the best Louisville Intl - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $258 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Louisville for as low as $141 on momondo.

What cabin class options are available on Louisville Intl to South Carolina flights?

There is only 1 cabin class available to choose from on Louisville Intl to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Louisville to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Louisville to South Carolina.

Cheap Louisville to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to South Carolina

Best Price Found	$120
Fastest flight time	1h 30m
Direct flights	Every day
Airports in South Carolina	57 airports

The best flight deal from Louisville to South Carolina found on momondo in the last 72 hours is $120

The fastest flight from Louisville to South Carolina takes 1h 30m

Direct flights go from Louisville to South Carolina every day.

There are 57 airports in South Carolina. From Louisville there are direct flights to Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Louisville to South Carolina

When did momondo last update prices for flights from Louisville Intl Airport to South Carolina?
Prices for flights from Louisville Intl Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Louisville Intl Airport to South Carolina?
There are 7 operators available for flights from Louisville Intl Airport to South Carolina as of April 2026.
How old do you have to be to fly from Louisville Intl Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Louisville to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Louisville to South Carolina is Airbus A320-100/200 (44.44% of total bookings). The next most popular plane models are Airbus A220-300 (27.78%), Embraer 190 (4.17%), and Airbus A321 (sharklets) (4.17%).

Best airlines flying from Louisville to South Carolina

Compare and see reviews for airlines that fly from Louisville to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $60	Free Cancellation	Rating 7.3 709 reviews	Search Allegiant Air flights
Breeze Airways	PriceFrom $77	Free Cancellation	Rating 8.1 275 reviews	Search Breeze Airways flights
Spirit Airlines	PriceFrom $79	Free Cancellation	Rating 6.3 8,572 reviews	Search Spirit Airlines flights
Delta	PriceFrom $118	Free Cancellation	Rating 7.9 8,370 reviews	Search Delta flights
United Airlines	PriceFrom $148	Free Cancellation	Rating 7.4 9,530 reviews	Search United Airlines flights
American Airlines	PriceFrom $183	Free Cancellation	Rating 7.1 11,548 reviews	Search American Airlines flights
Southwest	PriceFrom $219	Free Cancellation	Rating 8.0 4,334 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Louisville to South Carolina for you.

Can I find flights from Louisville to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to South Carolina?

Once you have performed a search for Louisville to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Louisville to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

An easier way to manage your South Carolina trip

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Flights to Las Vegasfrom $54

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Flights to Dallasfrom $55

Flights to Fort Lauderdalefrom $56

Cheap flights from Louisville to South Carolina from $54

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to South Carolina departing on 7/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Our best Delta deals on Louisville to South Carolina flight tickets

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Our best Spirit Airlines deals on Louisville to South Carolina flight tickets

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See travel insights to South Carolina from

How to get the cheapest flight ticket from Louisville to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Louisville Intl to South Carolina flight route?

How far in advance should I book a flight to South Carolina?

What cabin class options are available on Louisville Intl to South Carolina flights?

Can stopping save me money on Louisville to South Carolina flights?

What is the cheapest airline that flies from Louisville Intl to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Louisville to South Carolina on average per week?

Cheap Louisville to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Frequently asked questions about flying from Louisville to South Carolina

Best airlines flying from Louisville to South Carolina

Compare and see reviews for airlines that fly from Louisville to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

Louisville flight routes

According to popular flight searches on momondo this year

South Carolina flight routes

According to popular flight searches on momondo this year

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