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Cheap flights from Louisville to South Carolina from $40

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to South Carolina departing on 8/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to South Carolina

Cheap round-trip flights

Breeze Airways Logo
8:35 pm - 10:11 pmSDF-CHS
1h 36mnonstop
Breeze Airways Logo
7:05 am - 8:52 amCHS-SDF
1h 47mnonstop
$88Breeze Airways
Find Deal
Mon, Aug 18 - Fri, Aug 22
Breeze Airways Logo
8:52 pm - 10:28 pmSDF-CHS
1h 36mnonstop
Breeze Airways Logo
7:05 am - 8:58 amCHS-SDF
1h 53mnonstop
$92Breeze Airways
Find Deal
Mon, Sep 8 - Fri, Sep 12
Spirit Airlines Logo
8:30 am - 8:06 pmSDF-MYR
11h 36m1 stop
Spirit Airlines Logo
4:23 pm - 10:28 pmMYR-SDF
6h 05m1 stop
$119Spirit Airlines
Find Deal
Mon, Sep 15 - Sat, Sep 20
Spirit Airlines Logo
8:30 am - 8:06 pmSDF-MYR
11h 36m1 stop
Spirit Airlines Logo
4:23 pm - 10:28 pmMYR-SDF
6h 05m1 stop
$121Spirit Airlines
Find Deal
Sat, Sep 6 - Sat, Sep 13
Southwest Logo
11:50 am - 4:35 pmSDF-CLT
4h 45m1 stop
Southwest Logo
6:30 am - 12:25 pmCLT-SDF
5h 55m1 stop
$196Southwest
Find Deal
Wed, Aug 27 - Wed, Sep 3
American Airlines Logo
6:08 am - 1:14 pmSDF-CHS
7h 06m1 stop
American Airlines Logo
3:57 pm - 9:30 pmCHS-SDF
5h 33m1 stop
$197American Airlines
Find Deal
Wed, Aug 27 - Wed, Sep 3
Delta Logo
8:10 am - 1:35 pmSDF-MYR
5h 25m1 stop
Delta Logo
6:56 pm - 11:56 pmMYR-SDF
5h 00m1 stop
$197Delta
Find Deal
Tue, Aug 26 - Tue, Sep 2
Delta Logo
7:05 am - 10:09 amSDF-GSP
3h 04m1 stop
Delta Logo
5:30 am - 8:54 amGSP-SDF
3h 24m1 stop
$197Delta
Find Deal
Tue, Oct 14 - Tue, Oct 21
American Airlines Logo
10:57 am - 6:46 pmSDF-MYR
7h 49m2 stops
American Airlines Logo
2:59 pm - 7:05 pmMYR-SDF
4h 06m1 stop
$202American Airlines
Find Deal
Tue, Sep 9 - Tue, Sep 16
Southwest Logo
11:50 am - 8:00 pmSDF-CLT
8h 10m2 stops
Southwest Logo
6:30 am - 12:25 pmCLT-SDF
5h 55m1 stop
$202Southwest
Find Deal
Wed, Aug 27 - Wed, Sep 3

American Airlines flights from Louisville to South Carolina

Our best American Airlines deals on Louisville to South Carolina flight tickets
American Airlines
Aug 27
SDF6:08 amLouisville Intl
7h 06m
1 stop
CHS1:14 pmCharleston
Sep 3
CHS3:57 pmCharleston
5h 33m
1 stop
SDF9:30 pmLouisville Intl
$197
Find similar
American Airlines
Sep 9
SDF10:57 amLouisville Intl
7h 49m
2 stops
MYR6:46 pmMyrtle Beach Intl
Sep 16
MYR2:59 pmMyrtle Beach Intl
4h 06m
1 stop
SDF7:05 pmLouisville Intl
$202
Find similar
American Airlines
Aug 26
SDF7:44 amLouisville Intl
7h 07m
2 stops
MYR2:51 pmMyrtle Beach Intl
Sep 2
MYR7:24 pmMyrtle Beach Intl
3h 44m
1 stop
SDF11:08 pmLouisville Intl
$210
Find similar

Spirit Airlines flights from Louisville to South Carolina

Our best Spirit Airlines deals on Louisville to South Carolina flight tickets
Spirit Airlines
Sep 15
SDF8:30 amLouisville Intl
11h 36m
1 stop
MYR8:06 pmMyrtle Beach Intl
Sep 20
MYR4:23 pmMyrtle Beach Intl
6h 05m
1 stop
SDF10:28 pmLouisville Intl
$119
Find similar
Spirit Airlines
Sep 6
SDF8:30 amLouisville Intl
11h 36m
1 stop
MYR8:06 pmMyrtle Beach Intl
Sep 13
MYR4:23 pmMyrtle Beach Intl
6h 05m
1 stop
SDF10:28 pmLouisville Intl
$121
Find similar
Spirit Airlines
Sep 6
SDF8:30 amLouisville Intl
11h 36m
1 stop
MYR8:06 pmMyrtle Beach Intl
Sep 13
MYR4:23 pmMyrtle Beach Intl
6h 05m
1 stop
SDF10:28 pmLouisville Intl
$122
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Mon 8/18

8:35 pm-10:11 pm

Nonstop1h 36m

Charleston

Fri 8/22

7:05 am-8:52 am

Nonstop1h 47m

$88

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Mon 9/8

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Fri 9/12

7:05 am-8:58 am

Nonstop1h 53m

$92

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Mon 9/15

8:30 am-8:06 pm

1 stop11h 36m

Myrtle Beach Intl

Sat 9/20

4:23 pm-10:28 pm

1 stop6h 05m

$119

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Sat 9/6

8:30 am-8:06 pm

1 stop11h 36m

Myrtle Beach Intl

Sat 9/13

4:23 pm-10:28 pm

1 stop6h 05m

$121

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Wed 8/27

11:50 am-4:35 pm

1 stop4h 45m

Charlotte Douglas

Wed 9/3

6:30 am-12:25 pm

1 stop5h 55m

$196

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Wed 8/27

6:08 am-1:14 pm

1 stop7h 06m

Charleston

Wed 9/3

3:57 pm-9:30 pm

1 stop5h 33m

$197

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Tue 8/26

8:10 am-1:35 pm

1 stop5h 25m

Myrtle Beach Intl

Tue 9/2

6:56 pm-11:56 pm

1 stop5h 00m

$197

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 10/14

7:05 am-10:09 am

1 stop3h 04m

Greenville

Tue 10/21

5:30 am-8:54 am

1 stop3h 24m

$197

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Tue 9/9

10:57 am-6:46 pm

2 stops7h 49m

Myrtle Beach Intl

Tue 9/16

2:59 pm-7:05 pm

1 stop4h 06m

$202

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Wed 8/27

11:50 am-8:00 pm

2 stops8h 10m

Charlotte Douglas

Wed 9/3

6:30 am-12:25 pm

1 stop5h 55m

$202

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Louisville to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Louisville is in August. Flight prices, which tend to average around $118, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Louisville during November instead. Flights to South Carolina in November, while not as cheap as those in August, still average around $219.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Friday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $124. The most expensive day to fly to South Carolina is Wednesday, with ticket prices averaging around $204.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Louisville to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $129. Try not to purchase tickets in the afternoon because they tend to be around $322. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Louisville Intl to South Carolina flight route?

Fly from Louisville Intl to Charleston for the best Louisville Intl - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $281 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Louisville for as low as $215 on momondo.

What cabin class options are available on Louisville Intl to South Carolina flights?

There are 1 cabin classes available to choose from on Louisville Intl to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Louisville to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Louisville to South Carolina.

Cheap Louisville to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to South Carolina

Best Price Found

$40

Fastest flight time

1h 34m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in South Carolina

8 airports
The best one-way flight to South Carolina from Louisville in the past 72 hours is $40. The best round-trip flight deal from Louisville to South Carolina found on momondo in the last 72 hours is $88.
The fastest flight from Louisville to South Carolina takes 1h 34m
Direct flights go from Louisville to South Carolina on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. Airlines offering direct flights are: Breeze Airways, Allegiant Air and American Airlines.
There are 8 airports near South Carolina: Greenville (GSP), Columbia Metropolitan (CAE), Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Hilton Head Island (HHH), Charlotte Douglas (CLT), Augusta Bush Field (AGS), Charleston (CHS)
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  • When did momondo last update prices for flights from Louisville Intl Airport to South Carolina?

    Prices for flights from Louisville Intl Airport to South Carolina refresh daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to South Carolina?

  • How old do you have to be to fly from Louisville Intl Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Louisville to South Carolina?

Best airlines flying from Louisville to South Carolina

Compare and see reviews for airlines that fly from Louisville to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $60Free CancellationRating
8.0
191 reviews
Search Breeze Airways flights
Allegiant AirPriceFrom $77Free CancellationRating
7.2
702 reviews
Search Allegiant Air flights
Spirit AirlinesPriceFrom $87Free CancellationRating
6.3
8,048 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $148Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
DeltaPriceFrom $177Free CancellationRating
8.0
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $190Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $219Free CancellationRating
8.0
4,246 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Louisville to South Carolina for you.

Can I find flights from Louisville to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to South Carolina?

Once you have performed a search for Louisville to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Louisville to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

An easier way to manage your South Carolina trip

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