What airlines fly to South Carolina?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to South Carolina from Louisville according to our data. Allegiant Air is the first choice among our users, with 42% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Louisville to South Carolina on average per week?

The number of flights available between Louisville and South Carolina is 56 per week as of July 2026. The most frequent departure day is Mon, with 16% of weekly flights leaving on this day.

How many flights depart from Louisville to South Carolina on average per day?

The number of flights available between Louisville and South Carolina is 8 per day as of July 2026. The most frequent departure time is 8:00PM, with 66% of daily flights leaving in the evening.

What is the cheapest airline that flies from Louisville Intl to South Carolina?

Allegiant Air, Breeze Airways, and Delta are the most popular carriers operating from Louisville Intl to South Carolina

When did momondo last update prices for flights from Louisville Intl Airport to South Carolina?

Prices for flights from Louisville Intl Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Louisville Intl Airport to South Carolina?

There are 6 operators available for flights from Louisville Intl Airport to South Carolina as of July 2026.

How old do you have to be to fly from Louisville Intl Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$35 Cheap Flights from Louisville to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:11 pm - 2:43 pm

SDF

MYR

1h 32mnonstop

10:39 am - 12:21 pm

MYR

SDF

1h 42mnonstop

$65Allegiant Air

Sat, Aug 8 - Sat, Aug 15

1:11 pm - 2:43 pm

SDF

MYR

1h 32mnonstop

10:39 am - 12:21 pm

MYR

SDF

1h 42mnonstop

$66Allegiant Air

Sat, Aug 8 - Sat, Aug 15

7:59 pm - 9:34 pm

SDF

CHS

1h 35mnonstop

6:10 am - 8:02 am

CHS

SDF

1h 52mnonstop

$97Breeze Airways

Fri, Sep 18 - Mon, Sep 21

8:28 pm - 10:06 pm

SDF

CHS

1h 38mnonstop

7:00 am - 8:46 am

CHS

SDF

1h 46mnonstop

$102Breeze Airways

Mon, Aug 17 - Mon, Aug 31

10:43 am - 3:26 pm

SDF

HHH

4h 43m

1 stop

12:15 pm - 4:51 pm

HHH

SDF

4h 36m

1 stop

$261Delta

Tue, Oct 20 - Tue, Oct 27

10:43 am - 3:26 pm

SDF

HHH

4h 43m

1 stop

12:15 pm - 9:14 pm

HHH

SDF

8h 59m

2 stops

$266Delta

Tue, Oct 20 - Tue, Oct 27

8:16 am - 2:47 pm

SDF

GSP

6h 31m

1 stop

7:05 pm - 11:11 pm

GSP

SDF

4h 06m

1 stop

$273American Airlines

Sat, Aug 8 - Mon, Aug 10

11:05 am - 4:35 pm

SDF

CAE

5h 30m

1 stop

10:31 am - 2:51 pm

CAE

SDF

4h 20m

1 stop

$280American Airlines

Wed, Aug 12 - Wed, Aug 19

12:05 pm - 6:20 pm

SDF

CLT

6h 15m

1 stop

6:30 am - 12:05 pm

CLT

SDF

5h 35m

1 stop

$289Southwest

Sat, Aug 29 - Sat, Sep 5

3:05 pm - 7:45 pm

SDF

GSP

4h 40m

1 stop

6:40 am - 12:10 pm

GSP

SDF

5h 30m

1 stop

$293Southwest

Wed, Dec 16 - Thu, Dec 17

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Southwest flights from Louisville to South Carolina

Our best Southwest deals on Louisville to South Carolina flight tickets

Southwest

Sep 9

SDF8:45 amLouisville Intl

10h 25m

2 stops

MYR7:10 pmMyrtle Beach Intl

Sep 14

MYR6:15 pmMyrtle Beach Intl

4h 20m

1 stop

SDF10:35 pmLouisville Intl

$278

Southwest

Aug 29

SDF12:05 pmLouisville Intl

6h 15m

1 stop

CLT6:20 pmCharlotte Douglas

Sep 5

CLT6:30 amCharlotte Douglas

5h 35m

1 stop

SDF12:05 pmLouisville Intl

$289

Southwest

Jul 31

SDF5:50 amLouisville Intl

9h 45m

2 stops

CHS3:35 pmCharleston

Aug 7

CHS11:35 amCharleston

6h 55m

1 stop

SDF6:30 pmLouisville Intl

$371

Breeze Airways flights from Louisville to South Carolina

Our best Breeze Airways deals on Louisville to South Carolina flight tickets

Breeze Airways

Sep 18

SDF7:59 pmLouisville Intl

1h 35m

CHS9:34 pmCharleston

Sep 21

CHS6:10 amCharleston

1h 52m

SDF8:02 amLouisville Intl

$97

Breeze Airways

Aug 17

SDF8:28 pmLouisville Intl

1h 38m

CHS10:06 pmCharleston

Aug 31

CHS7:00 amCharleston

1h 46m

SDF8:46 amLouisville Intl

$102

Breeze Airways

Aug 28

SDF8:28 pmLouisville Intl

1h 38m

CHS10:06 pmCharleston

Aug 31

CHS7:00 amCharleston

1h 46m

SDF8:46 amLouisville Intl

$103

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Sat 8/8

1:11 pm-2:43 pm

Nonstop1h 32m

Myrtle Beach Intl

Sat 8/15

10:39 am-12:21 pm

Nonstop1h 42m

$65

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Sat 8/8

1:11 pm-2:43 pm

Nonstop1h 32m

Myrtle Beach Intl

Sat 8/15

10:39 am-12:21 pm

Nonstop1h 42m

$66

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 9/18

7:59 pm-9:34 pm

Nonstop1h 35m

Charleston

Mon 9/21

6:10 am-8:02 am

Nonstop1h 52m

$97

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Mon 8/17

8:28 pm-10:06 pm

Nonstop1h 38m

Charleston

Mon 8/31

7:00 am-8:46 am

Nonstop1h 46m

$102

LouisvilleHilton Head Island

SDF - HHH

SDFHHH

Louisville Intl

Tue 10/20

10:43 am-3:26 pm

1 stop4h 43m

Hilton Head Island

Tue 10/27

12:15 pm-4:51 pm

1 stop4h 36m

$261

LouisvilleHilton Head Island

SDF - HHH

SDFHHH

Louisville Intl

Tue 10/20

10:43 am-3:26 pm

1 stop4h 43m

Hilton Head Island

Tue 10/27

12:15 pm-9:14 pm

2 stops8h 59m

$266

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sat 8/8

8:16 am-2:47 pm

1 stop6h 31m

Greenville

Mon 8/10

7:05 pm-11:11 pm

1 stop4h 06m

$273

LouisvilleColumbia

SDF - CAE

SDFCAE

Louisville Intl

Wed 8/12

11:05 am-4:35 pm

1 stop5h 30m

Columbia Metropolitan

Wed 8/19

10:31 am-2:51 pm

1 stop4h 20m

$280

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Sat 8/29

12:05 pm-6:20 pm

1 stop6h 15m

Charlotte Douglas

Sat 9/5

6:30 am-12:05 pm

1 stop5h 35m

$289

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Wed 12/16

3:05 pm-7:45 pm

1 stop4h 40m

Greenville

Thu 12/17

6:40 am-12:10 pm

1 stop5h 30m

$293

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Louisville to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Louisville is in September. Flight prices, which tend to average around $216, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Louisville during July instead. Flights to South Carolina in July, while not as cheap as those in September, still average around $234.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Friday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $146. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $150.

What is the cheapest Louisville Intl to South Carolina flight route?

Fly from Louisville Intl to Charleston for the best Louisville Intl - South Carolina flight prices

How far in advance should I book a flight from Louisville to South Carolina?

You are more likely to see cheaper flights to South Carolina from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $264 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Louisville for as low as $152 on momondo.

What cabin class options are available on Louisville to South Carolina flights?

There are 2 cabin classes available to choose from on Louisville to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Louisville to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Louisville to South Carolina.

Cheap Louisville to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to South Carolina

Best Price Found	$82
Fastest flight time	1h 30m
Direct flights	Mon, Tue, Wed, Fri and Sun
Airports in South Carolina	57 airports

The best flight deal from Louisville to South Carolina found on momondo in the last 72 hours is $82

The fastest flight from Louisville to South Carolina takes 1h 30m

Direct flights go from Louisville to South Carolina on Monday, Tuesday, Wednesday, Friday and Sunday. Airlines offering direct flights are: Breeze Airways and Allegiant Air.

There are 57 airports in South Carolina. From Louisville there are direct flights to Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Louisville to South Carolina

When did momondo last update prices for flights from Louisville Intl Airport to South Carolina?
Prices for flights from Louisville Intl Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Louisville Intl Airport to South Carolina?
There are 6 operators available for flights from Louisville Intl Airport to South Carolina as of July 2026.
How old do you have to be to fly from Louisville Intl Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Louisville to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Louisville to South Carolina is Airbus A220-300 (50.00% of total bookings). The next most popular plane models are Airbus A320-100/200 (35.85%), Embraer 190 (2.83%), and Airbus A321 (sharklets) (2.83%).

Best airlines flying from Louisville to South Carolina

Compare and see reviews for airlines that fly from Louisville to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $66	Free Cancellation	Rating 7.3 681 reviews	Search Allegiant Air flights
Breeze Airways	PriceFrom $88	Free Cancellation	Rating 8.2 300 reviews	Search Breeze Airways flights
Delta	PriceFrom $118	Free Cancellation	Rating 7.8 8,476 reviews	Search Delta flights
American Airlines	PriceFrom $196	Free Cancellation	Rating 7.1 11,825 reviews	Search American Airlines flights
Southwest	PriceFrom $236	Free Cancellation	Rating 8.0 4,243 reviews	Search Southwest flights
United Airlines	PriceFrom $274	Free Cancellation	Rating 7.4 10,015 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Louisville to South Carolina for you.

Can I find flights from Louisville to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to South Carolina?

Once you have performed a search for Louisville to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Louisville to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

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Popular cities in South Carolina

Flights to New Yorkfrom $72

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Flights to San Franciscofrom $55

Flights to Las Vegasfrom $46

Flights to Washington, D.C.from $56

Flights to Bostonfrom $63

Flights to Atlantafrom $55

Flights to Fort Lauderdalefrom $61

Flights to Dallasfrom $82

Cheap flights from Louisville to South Carolina from $35

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to South Carolina departing on 8/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Southwest flights from Louisville to South Carolina

Our best Southwest deals on Louisville to South Carolina flight tickets

Breeze Airways flights from Louisville to South Carolina

Our best Breeze Airways deals on Louisville to South Carolina flight tickets

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How to get the cheapest flight ticket from Louisville to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest Louisville Intl to South Carolina flight route?

How far in advance should I book a flight from Louisville to South Carolina?

What cabin class options are available on Louisville to South Carolina flights?

Can stopping save me money on Louisville to South Carolina flights?

What is the cheapest airline that flies from Louisville Intl to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Louisville to South Carolina on average per day?

How many flights depart from Louisville to South Carolina on average per week?

Cheap Louisville to South Carolina flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Frequently asked questions about flying from Louisville to South Carolina

Best airlines flying from Louisville to South Carolina

Compare and see reviews for airlines that fly from Louisville to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

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According to popular flight searches on momondo this year

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