What is the cheapest airline that flies from Louisville Intl to South Carolina?

Breeze Airways, United Airlines, and Southwest are the most popular carriers operating from Louisville Intl to South Carolina

What airlines fly to South Carolina?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to South Carolina from Louisville according to our data. Allegiant Air is the first choice among our users, with 40% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Louisville to South Carolina on average per week?

The number of flights available between Louisville and South Carolina is 2 per week as of October 2026. The most frequent departure day is Mon, with 50% of weekly flights leaving on this day.

When did momondo last update prices for flights from Louisville Intl Airport to South Carolina?

Prices for flights from Louisville Intl Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Louisville Intl Airport to South Carolina?

There are 6 operators available for flights from Louisville Intl Airport to South Carolina as of October 2026.

How old do you have to be to fly from Louisville Intl Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$53 Cheap Flights from Louisville to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:59 pm - 9:34 pmSDF Louisville Intl-CHS Charleston

1h 35mnonstop

6:10 am - 8:02 amCHS Charleston-SDF Louisville Intl

1h 52mnonstop

$113Breeze Airways

Fri, Oct 30 - Mon, Nov 2

7:59 pm - 9:34 pmSDF Louisville Intl-CHS Charleston

1h 35mnonstop

6:10 am - 8:02 amCHS Charleston-SDF Louisville Intl

1h 52mnonstop

$114Breeze Airways

Mon, Nov 9 - Fri, Nov 13

1:01 pm - 4:29 pmSDF Louisville Intl-CHS Charleston

3h 28m1 stop Atlanta Hartsfield-Jackson

5:49 pm - 9:42 pmCHS Charleston-SDF Louisville Intl

3h 53m1 stop Atlanta Hartsfield-Jackson

$217Delta

Mon, Nov 9 - Sat, Nov 14

7:55 pm - 11:59 pmSDF Louisville Intl-CHS Charleston

4h 04m1 stop Atlanta Hartsfield-Jackson

7:04 pm - 12:10 amCHS Charleston-SDF Louisville Intl

5h 06m1 stop Atlanta Hartsfield-Jackson

$217Delta

Sun, Nov 8 - Mon, Nov 9

12:50 pm - 6:40 pmSDF Louisville Intl-CHS Charleston

5h 50m1 stop Dallas Love Field

7:55 pm - 12:20 amCHS Charleston-SDF Louisville Intl

4h 25m1 stop Baltimore/Washington

$217Southwest

Fri, Oct 30 - Mon, Nov 2

5:35 pm - 8:55 pmSDF Louisville Intl-CHS Charleston

3h 20m1 stop Nashville Intl

7:55 pm - 12:25 amCHS Charleston-SDF Louisville Intl

4h 30m1 stop Baltimore/Washington

$217Southwest

Mon, Nov 2 - Fri, Nov 6

9:55 am - 2:28 pmSDF Louisville Intl-CHS Charleston

4h 33m1 stop Washington, D.C. Dulles Intl

3:29 pm - 10:30 pmCHS Charleston-SDF Louisville Intl

7h 01m1 stop Chicago O'Hare Intl

$217United Airlines

Mon, Nov 9 - Thu, Nov 12

5:10 am - 2:28 pmSDF Louisville Intl-CHS Charleston

9h 18m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

10:23 am - 2:47 pmCHS Charleston-SDF Louisville Intl

4h 24m1 stop Washington, D.C. Dulles Intl

$222United Airlines

Mon, Nov 9 - Thu, Nov 12

10:13 am - 3:24 pmSDF Louisville Intl-CHS Charleston

5h 11m1 stop Chicago O'Hare Intl

6:14 pm - 12:19 amCHS Charleston-SDF Louisville Intl

6h 05m1 stop Charlotte Douglas

$237American Airlines

Mon, Nov 9 - Fri, Nov 13

4:35 pm - 9:04 pmSDF Louisville Intl-CHS Charleston

4h 29m1 stop Charlotte Douglas

8:32 pm - 12:19 amCHS Charleston-SDF Louisville Intl

3h 47m1 stop Charlotte Douglas

$237American Airlines

Mon, Nov 2 - Fri, Nov 6

Cheap last minute flights

Enter your travel dates to find the best prices.

7:59 pm - 9:34 pmSDF Louisville Intl-CHS Charleston

1h 35mnonstop

6:10 am - 8:02 amCHS Charleston-SDF Louisville Intl

1h 52mnonstop

$203Breeze Airways

Fri, Oct 23 - Mon, Oct 26

9:22 pm - 10:33 pmSDF Louisville Intl-CHS Charleston

25h 11m1 stop Fort Myers SW Florida Intl

6:10 am - 8:02 amCHS Charleston-SDF Louisville Intl

1h 52mnonstop

$244Breeze Airways

Fri, Oct 23 - Mon, Oct 26

7:59 pm - 9:34 pmSDF Louisville Intl-CHS Charleston

1h 35mnonstop

3:27 pm - 10:11 amCHS Charleston-SDF Louisville Intl

42h 44m2 stops Orlando Raleigh-Durham

$395Multiple Airlines

Fri, Oct 23 - Mon, Oct 26

6:00 am - 9:47 amSDF Louisville Intl-CAE Columbia Metropolitan

3h 47m1 stop Washington, D.C. Dulles Intl

5:38 pm - 11:59 pmCAE Columbia Metropolitan-SDF Louisville Intl

6h 21m1 stop Chicago O'Hare Intl

$409United Airlines

Thu, Oct 22 - Sat, Oct 24

6:00 am - 9:30 amSDF Louisville Intl-CAE Columbia Metropolitan

3h 30m1 stop Atlanta Hartsfield-Jackson

10:10 am - 2:41 pmCAE Columbia Metropolitan-SDF Louisville Intl

4h 31m1 stop Atlanta Hartsfield-Jackson

$411Delta

Tue, Oct 20 - Sat, Oct 24

6:00 am - 9:30 amSDF Louisville Intl-CAE Columbia Metropolitan

3h 30m1 stop Atlanta Hartsfield-Jackson

7:00 am - 10:21 amCAE Columbia Metropolitan-SDF Louisville Intl

3h 21m1 stop Atlanta Hartsfield-Jackson

$411Delta

Tue, Oct 20 - Tue, Oct 27

7:59 pm - 9:34 pmSDF Louisville Intl-CHS Charleston

1h 35mnonstop

3:42 pm - 9:45 amCHS Charleston-SDF Louisville Intl

42h 03m2 stops Orlando Pittsburgh

$411Multiple Airlines

Fri, Oct 23 - Wed, Oct 28

6:00 am - 9:47 amSDF Louisville Intl-CAE Columbia Metropolitan

3h 47m1 stop Washington, D.C. Dulles Intl

3:03 pm - 11:27 pmCAE Columbia Metropolitan-SDF Louisville Intl

8h 24m2 stops Washington, D.C. Dulles Intl Newark

$414United Airlines

Thu, Oct 22 - Sat, Oct 24

5:04 am - 8:37 amSDF Louisville Intl-MYR Myrtle Beach Intl

3h 33m1 stop Charlotte Douglas

4:12 pm - 7:36 pmMYR Myrtle Beach Intl-SDF Louisville Intl

3h 24m1 stop Charlotte Douglas

$542American Airlines

Sat, Oct 24 - Sat, Oct 31

6:29 am - 1:31 pmSDF Louisville Intl-MYR Myrtle Beach Intl

7h 02m2 stops Chicago O'Hare Intl Charlotte Douglas

6:30 am - 11:17 amMYR Myrtle Beach Intl-SDF Louisville Intl

4h 47m1 stop Charlotte Douglas

$547American Airlines

Sat, Oct 24 - Sat, Oct 31

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Breeze Airways flights from Louisville to South Carolina

Our best Breeze Airways deals on Louisville to South Carolina flight tickets

Breeze Airways

Oct 30

SDF7:59 pmLouisville Intl

1h 35m

CHS9:34 pmCharleston

Nov 2

CHS6:10 amCharleston

1h 52m

SDF8:02 amLouisville Intl

$113

Breeze Airways

Nov 9

SDF7:59 pmLouisville Intl

1h 35m

CHS9:34 pmCharleston

Nov 13

CHS6:10 amCharleston

1h 52m

SDF8:02 amLouisville Intl

$114

Breeze Airways

Nov 6

SDF7:59 pmLouisville Intl

1h 35m

CHS9:34 pmCharleston

Nov 13

CHS6:10 amCharleston

1h 52m

SDF8:02 amLouisville Intl

$119

Delta flights from Louisville to South Carolina

Our best Delta deals on Louisville to South Carolina flight tickets

Delta

Nov 7

SDF7:05 amLouisville Intl

4h 02m

1 stop

CHS11:07 amCharleston

Nov 14

CHS5:49 pmCharleston

3h 53m

1 stop

SDF9:42 pmLouisville Intl

$217

Delta

Jan 15

SDF3:24 pmLouisville Intl

3h 30m

1 stop

CHS6:54 pmCharleston

Jan 18

CHS7:59 pmCharleston

4h 03m

1 stop

SDF12:02 amLouisville Intl

$237

Delta

Nov 9

SDF6:00 amLouisville Intl

3h 47m

1 stop

GSP9:47 amGreenville

Nov 13

GSP5:40 amGreenville

6h 16m

1 stop

SDF11:56 amLouisville Intl

$279

momondo Fare Finder

Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Fri 10/30

7:59 pm-9:34 pm

Nonstop1h 35m

Charleston

Mon 11/2

6:10 am-8:02 am

Nonstop1h 52m

$113

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Mon 11/9

7:59 pm-9:34 pm

Nonstop1h 35m

Charleston

Fri 11/13

6:10 am-8:02 am

Nonstop1h 52m

$114

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Mon 11/9

1:01 pm-4:29 pm

1 stop3h 28m

Charleston

Sat 11/14

5:49 pm-9:42 pm

1 stop3h 53m

$217

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Sun 11/8

7:55 pm-11:59 pm

1 stop4h 04m

Charleston

Mon 11/9

7:04 pm-12:10 am

1 stop5h 06m

$217

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Fri 10/30

12:50 pm-6:40 pm

1 stop5h 50m

Charleston

Mon 11/2

7:55 pm-12:20 am

1 stop4h 25m

$217

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Mon 11/2

5:35 pm-8:55 pm

1 stop3h 20m

Charleston

Fri 11/6

7:55 pm-12:25 am

1 stop4h 30m

$217

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Mon 11/9

9:55 am-2:28 pm

1 stop4h 33m

Charleston

Thu 11/12

3:29 pm-10:30 pm

1 stop7h 01m

$217

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Mon 11/9

5:10 am-2:28 pm

2 stops9h 18m

Charleston

Thu 11/12

10:23 am-2:47 pm

1 stop4h 24m

$222

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Mon 11/9

10:13 am-3:24 pm

1 stop5h 11m

Charleston

Fri 11/13

6:14 pm-12:19 am

1 stop6h 05m

$237

LouisvilleCharleston

SDF Louisville Intl - CHS Charleston

SDFCHS

Louisville Intl

Mon 11/2

4:35 pm-9:04 pm

1 stop4h 29m

Charleston

Fri 11/6

8:32 pm-12:19 am

1 stop3h 47m

$237

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Louisville to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Louisville is in July. Flight prices, which tend to average around $230, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of July, then book flights to South Carolina from Louisville during February instead. Flights to South Carolina in February, while not as cheap as those in July, still average around $264.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Friday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $158. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $158.

What is the cheapest Louisville Intl to South Carolina flight route?

Fly from Louisville Intl to Charleston for the best Louisville Intl - South Carolina flight prices

How far in advance should I book a flight from Louisville to South Carolina?

You are more likely to see cheaper flights to South Carolina from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $291 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Louisville for as low as $167 on momondo.

What cabin class options are available on Louisville to South Carolina flights?

There are 2 cabin classes available to choose from on Louisville to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Louisville to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Louisville to South Carolina.

Cheap Louisville to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to South Carolina

Best Price Found	$53
Fastest flight time	1h 35m
Direct flights	Tue and Sat
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Louisville in the past 72 hours is $53. The best round-trip flight deal from Louisville to South Carolina found on momondo in the last 72 hours is $113.

The fastest flight from Louisville to South Carolina takes 1h 35m

Direct flights go from Louisville to South Carolina on Tuesday and Saturday. The only airline offering direct flights is Breeze Airways.

There are 57 airports in South Carolina. From Louisville there are direct flights to Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Louisville to South Carolina

When did momondo last update prices for flights from Louisville Intl Airport to South Carolina?
Prices for flights from Louisville Intl Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Louisville Intl Airport to South Carolina?
There are 6 operators available for flights from Louisville Intl Airport to South Carolina as of October 2026.
How old do you have to be to fly from Louisville Intl Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Louisville to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Louisville to South Carolina is Airbus A220-300 (70.91% of total bookings). The next most popular plane models are Airbus A320-100/200 (23.64%), Airbus A319 (3.64%), and Boeing 737 MAX 8 (1.82%).

Best airlines flying from Louisville to South Carolina

Compare and see reviews for airlines that fly from Louisville to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $63	Free Cancellation	Rating 7.3 678 reviews	Search Allegiant Air flights
Breeze Airways	PriceFrom $88	Free Cancellation	Rating 8.2 327 reviews	Search Breeze Airways flights
Delta	PriceFrom $226	Free Cancellation	Rating 7.8 8,649 reviews	Search Delta flights
United Airlines	PriceFrom $234	Free Cancellation	Rating 7.3 10,390 reviews	Search United Airlines flights
American Airlines	PriceFrom $234	Free Cancellation	Rating 7.0 12,182 reviews	Search American Airlines flights
Southwest	PriceFrom $236	Free Cancellation	Rating 7.9 4,211 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Louisville to South Carolina for you.

Can I find flights from Louisville to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to South Carolina?

Once you have performed a search for Louisville to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Louisville to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.