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Cheap flights from Louisville to Key West from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Key West departing on 10/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
9:09 pm - 12:19 pmSDF  Louisville Intl-EYW Key West
15h 10m1 stop Tampa
Breeze Airways Logo
12:01 pm - 8:29 pmEYW  Key West-SDF Louisville Intl
8h 28m1 stop Tampa
$205Breeze Airways
Sun, Nov 15 - Thu, Nov 19
Breeze Airways Logo
9:09 pm - 12:19 pmSDF  Louisville Intl-EYW Key West
15h 10m1 stop Tampa
Breeze Airways Logo
12:01 pm - 8:29 pmEYW  Key West-SDF Louisville Intl
8h 28m1 stop Tampa
$209Breeze Airways
Sun, Nov 15 - Thu, Nov 19
Multiple Airlines Logo
10:25 am - 5:47 pmSDF  Louisville Intl-EYW Key West
7h 22m1 stop Pittsburgh
Multiple Airlines Logo
12:01 pm - 8:29 pmEYW  Key West-SDF Louisville Intl
8h 28m1 stop Tampa
$214Multiple Airlines
Mon, Oct 12 - Thu, Oct 15
American Airlines Logo
1:15 pm - 6:01 pmSDF  Louisville Intl-EYW Key West
4h 46m1 stop Charlotte Douglas
American Airlines Logo
7:08 am - 12:25 pmEYW  Key West-SDF Louisville Intl
5h 17m1 stop Charlotte Douglas
$333American Airlines
Wed, Jan 13 - Sat, Jan 16
Delta Logo
3:00 pm - 8:02 pmSDF  Louisville Intl-EYW Key West
5h 02m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:35 am - 11:56 amEYW  Key West-SDF Louisville Intl
4h 21m1 stop Atlanta Hartsfield-Jackson
$333Delta
Sat, Dec 5 - Tue, Dec 8
Delta Logo
1:59 pm - 8:01 pmSDF  Louisville Intl-EYW Key West
6h 02m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:10 pm - 11:59 pmEYW  Key West-SDF Louisville Intl
5h 49m1 stop Atlanta Hartsfield-Jackson
$333Delta
Wed, Oct 7 - Wed, Oct 14
Delta Logo
1:59 pm - 8:01 pmSDF  Louisville Intl-EYW Key West
6h 02m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:10 pm - 11:59 pmEYW  Key West-SDF Louisville Intl
5h 49m1 stop Atlanta Hartsfield-Jackson
$333Delta
Wed, Oct 7 - Tue, Oct 13
American Airlines Logo
6:00 am - 1:17 pmSDF  Louisville Intl-EYW Key West
7h 17m1 stop Miami
American Airlines Logo
6:27 pm - 11:22 pmEYW  Key West-SDF Louisville Intl
4h 55m1 stop Charlotte Douglas
$338American Airlines
Wed, Sep 16 - Mon, Sep 21
United Airlines Logo
6:15 am - 1:29 pmSDF  Louisville Intl-EYW Key West
7h 14m1 stop Newark
United Airlines Logo
4:00 pm - 11:59 pmEYW  Key West-SDF Louisville Intl
7h 59m1 stop Chicago O'Hare Intl
$373United Airlines
Sun, Sep 20 - Sat, Sep 26
United Airlines Logo
5:30 am - 4:22 pmSDF  Louisville Intl-EYW Key West
10h 52m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
United Airlines Logo
2:30 pm - 11:15 pmEYW  Key West-SDF Louisville Intl
8h 45m1 stop Newark
$378United Airlines
Fri, Jan 29 - Wed, Feb 3

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Breeze Airways flights from Louisville to Key West

Our best Breeze Airways deals on Louisville to Key West flight tickets
Breeze Airways
Nov 15
SDF9:09 pmLouisville Intl
15h 10m
1 stop
EYW12:19 pmKey West
Nov 19
EYW12:01 pmKey West
8h 28m
1 stop
SDF8:29 pmLouisville Intl
$205
Breeze Airways
Nov 15
SDF9:09 pmLouisville Intl
15h 10m
1 stop
EYW12:19 pmKey West
Nov 19
EYW12:01 pmKey West
8h 28m
1 stop
SDF8:29 pmLouisville Intl
$209
Breeze Airways
Aug 26
SDF2:56 pmLouisville Intl
28h 17m
2 stops
EYW7:13 pmKey West
Sep 2
EYW11:46 amKey West
22h 46m
1 stop
SDF10:32 amLouisville Intl
$215

Delta flights from Louisville to Key West

Our best Delta deals on Louisville to Key West flight tickets
Delta
Dec 1
SDF1:01 pmLouisville Intl
7h 01m
1 stop
EYW8:02 pmKey West
Dec 5
EYW6:02 pmKey West
6h 03m
1 stop
SDF12:05 amLouisville Intl
$333
Delta
Nov 5
SDF1:59 pmLouisville Intl
6h 02m
1 stop
EYW8:01 pmKey West
Nov 10
EYW7:35 amKey West
4h 21m
1 stop
SDF11:56 amLouisville Intl
$338
Delta
Oct 23
SDF7:05 amLouisville Intl
5h 48m
1 stop
EYW12:53 pmKey West
Oct 30
EYW6:10 pmKey West
5h 49m
1 stop
SDF11:59 pmLouisville Intl
$343

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from Louisville to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Sun 11/15

9:09 pm-12:19 pm

1 stop15h 10m

Key West

Thu 11/19

12:01 pm-8:29 pm

1 stop8h 28m

$205

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Sun 11/15

9:09 pm-12:19 pm

1 stop15h 10m

Key West

Thu 11/19

12:01 pm-8:29 pm

1 stop8h 28m

$209

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Mon 10/12

10:25 am-5:47 pm

1 stop7h 22m

Key West

Thu 10/15

12:01 pm-8:29 pm

1 stop8h 28m

$214

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Wed 1/13

1:15 pm-6:01 pm

1 stop4h 46m

Key West

Sat 1/16

7:08 am-12:25 pm

1 stop5h 17m

$333
Quickest round-trip

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Sat 12/5

3:00 pm-8:02 pm

1 stop5h 02m

Key West

Tue 12/8

7:35 am-11:56 am

1 stop4h 21m

$333

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Wed 10/7

1:59 pm-8:01 pm

1 stop6h 02m

Key West

Wed 10/14

6:10 pm-11:59 pm

1 stop5h 49m

$333

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Wed 10/7

1:59 pm-8:01 pm

1 stop6h 02m

Key West

Tue 10/13

6:10 pm-11:59 pm

1 stop5h 49m

$333

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Wed 9/16

6:00 am-1:17 pm

1 stop7h 17m

Key West

Mon 9/21

6:27 pm-11:22 pm

1 stop4h 55m

$338

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Sun 9/20

6:15 am-1:29 pm

1 stop7h 14m

Key West

Sat 9/26

4:00 pm-11:59 pm

1 stop7h 59m

$373

LouisvilleKey West

SDF Louisville Intl - EYW Key West

SDFEYW

Louisville Intl

Fri 1/29

5:30 am-4:22 pm

2 stops10h 52m

Key West

Wed 2/3

2:30 pm-11:15 pm

1 stop8h 45m

$378

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Louisville to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Key West?

Prices are currently low for flights on this route.

Typical prices usually range from $322 to $593.
The lowest price recently found on this route was $205.

What is the cheapest month to fly to Key West?

In general, February is the cheapest month to fly from Louisville to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $349. If you are unable to visit Key West during the month of February, then departing from Louisville during the month January is also very affordable. Most momondo users find prices during this month for around $352.

How far in advance should I book a flight from Louisville to Key West?

You are more likely to see cheaper flights to Key West from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $462 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Louisville for as low as $280 on momondo.

When to book flights from Louisville to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Key West (SDF to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Key West

Fastest flight time

4h 46m

Direct flights

None
The fastest flight from Louisville to Key West takes 4h 46m
There are no direct flights from Louisville to Key West. There are no popular flight routes from Louisville to Key West.
Search flight deals

Frequently asked questions about flying from Louisville to Key West

  • How far is Louisville Intl to Key West by plane?

    Louisville Intl and Key West are 973.5 mi apart from one another. In terms of flight time, this usually takes a little over 4h 46m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Key West Airport?

    Prices for flights from Louisville Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Key West Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Louisville to Key West?

Best airlines flying from Louisville to Key West

Compare and see reviews for airlines that fly from Louisville to Key West with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $258Free CancellationRating
7.4
10,111 reviews
Search United Airlines flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,941 reviews
Search American Airlines flights
DeltaPriceFrom $282Free CancellationRating
7.8
8,508 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Key West?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Key West. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Key West with flexible booking policies on momondo?

All flight searches from Louisville to Key West on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Louisville.

I’m not ready to book a flight from Louisville to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Louisville and alert you when they change.

An easier way to manage your Key West trip

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