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Cheap flights from Louisville to Key West from $118

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Key West departing on 5/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:26 pm - 10:24 am
SDF
-
EYW
19h 58m
1 stop
Multiple Airlines Logo
2:25 pm - 8:40 am
EYW
-
SDF
18h 15m
1 stop
$262Multiple Airlines
Sun, Mar 1 - Thu, Mar 5
Multiple Airlines Logo
2:26 pm - 10:24 am
SDF
-
EYW
19h 58m
1 stop
Multiple Airlines Logo
9:46 am - 12:21 pm
EYW
-
SDF
26h 35m
1 stop
$269Multiple Airlines
Sun, Mar 1 - Thu, Mar 5
Multiple Airlines Logo
6:55 pm - 4:58 pm
SDF
-
EYW
22h 03m
1 stop
Multiple Airlines Logo
12:05 pm - 11:41 am
EYW
-
SDF
23h 36m
1 stop
$271Multiple Airlines
Sun, May 10 - Thu, May 14
American Airlines Logo
6:01 am - 11:40 am
SDF
-
EYW
5h 39m
1 stop
American Airlines Logo
7:33 pm - 11:59 pm
EYW
-
SDF
4h 26m
1 stop
$279American Airlines
Tue, Jun 30 - Sat, Jul 4
Multiple Airlines Logo
7:48 pm - 11:30 am
SDF
-
EYW
15h 42m
1 stop
Multiple Airlines Logo
12:06 pm - 6:58 pm
EYW
-
SDF
6h 52m
1 stop
$284Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
2:26 pm - 10:24 am
SDF
-
EYW
19h 58m
1 stop
Multiple Airlines Logo
4:22 pm - 8:40 am
EYW
-
SDF
16h 18m
2 stops
$288Multiple Airlines
Sun, Mar 1 - Thu, Mar 5
Multiple Airlines Logo
3:33 pm - 1:30 pm
SDF
-
EYW
21h 57m
1 stop
Multiple Airlines Logo
9:46 am - 12:21 pm
EYW
-
SDF
26h 35m
1 stop
$292Multiple Airlines
Thu, Mar 5 - Sun, Mar 8
Multiple Airlines Logo
2:26 pm - 10:24 am
SDF
-
EYW
19h 58m
1 stop
Multiple Airlines Logo
4:22 pm - 8:40 am
EYW
-
SDF
16h 18m
2 stops
$298Multiple Airlines
Sun, Mar 1 - Thu, Mar 5
Delta Logo
6:03 am - 12:42 pm
SDF
-
EYW
6h 39m
1 stop
Delta Logo
6:22 pm - 11:59 pm
EYW
-
SDF
5h 37m
1 stop
$309Delta
Wed, May 20 - Sat, May 23
Multiple Airlines Logo
1:19 pm - 9:06 am
SDF
-
EYW
19h 47m
1 stop
Multiple Airlines Logo
9:46 am - 12:21 pm
EYW
-
SDF
26h 35m
1 stop
$320Multiple Airlines
Wed, Mar 4 - Sun, Mar 8

Delta flights from Louisville to Key West

Our best Delta deals on Louisville to Key West flight tickets
Delta
May 20
SDF6:03 amLouisville Intl
6h 39m
1 stop
EYW12:42 pmKey West
May 23
EYW6:22 pmKey West
5h 37m
1 stop
SDF11:59 pmLouisville Intl
$309
Delta
May 15
SDF6:00 amLouisville Intl
4h 53m
1 stop
EYW10:53 amKey West
May 18
EYW6:22 pmKey West
5h 58m
1 stop
SDF12:20 amLouisville Intl
$379
Delta
Mar 5
SDF6:00 amLouisville Intl
6h 45m
1 stop
EYW12:45 pmKey West
Mar 9
EYW6:25 pmKey West
5h 32m
1 stop
SDF11:57 pmLouisville Intl
$394

American Airlines flights from Louisville to Key West

Our best American Airlines deals on Louisville to Key West flight tickets
American Airlines
Jun 30
SDF6:01 amLouisville Intl
5h 39m
1 stop
EYW11:40 amKey West
Jul 4
EYW7:33 pmKey West
4h 26m
1 stop
SDF11:59 pmLouisville Intl
$279
American Airlines
May 13
SDF7:33 amLouisville Intl
5h 48m
1 stop
EYW1:21 pmKey West
May 16
EYW2:01 pmKey West
5h 01m
1 stop
SDF7:02 pmLouisville Intl
$334
American Airlines
May 13
SDF7:33 amLouisville Intl
8h 57m
2 stops
EYW4:30 pmKey West
May 16
EYW2:01 pmKey West
5h 01m
1 stop
SDF7:02 pmLouisville Intl
$339

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 17, 2026.
Use the filters below to find and compare flights from Louisville to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sun 3/1

2:26 pm-10:24 am

1 stop19h 58m

Key West

Thu 3/5

2:25 pm-8:40 am

1 stop18h 15m

$262

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sun 3/1

2:26 pm-10:24 am

1 stop19h 58m

Key West

Thu 3/5

9:46 am-12:21 pm

1 stop26h 35m

$269

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sun 5/10

6:55 pm-4:58 pm

1 stop22h 03m

Key West

Thu 5/14

12:05 pm-11:41 am

1 stop23h 36m

$271

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Tue 6/30

6:01 am-11:40 am

1 stop5h 39m

Key West

Sat 7/4

7:33 pm-11:59 pm

1 stop4h 26m

$279

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Mon 4/13

7:48 pm-11:30 am

1 stop15h 42m

Key West

Fri 4/17

12:06 pm-6:58 pm

1 stop6h 52m

$284

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sun 3/1

2:26 pm-10:24 am

1 stop19h 58m

Key West

Thu 3/5

4:22 pm-8:40 am

2 stops16h 18m

$288

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 3/5

3:33 pm-1:30 pm

1 stop21h 57m

Key West

Sun 3/8

9:46 am-12:21 pm

1 stop26h 35m

$292

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sun 3/1

2:26 pm-10:24 am

1 stop19h 58m

Key West

Thu 3/5

4:22 pm-8:40 am

2 stops16h 18m

$298

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Wed 5/20

6:03 am-12:42 pm

1 stop6h 39m

Key West

Sat 5/23

6:22 pm-11:59 pm

1 stop5h 37m

$309

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Wed 3/4

1:19 pm-9:06 am

1 stop19h 47m

Key West

Sun 3/8

9:46 am-12:21 pm

1 stop26h 35m

$320

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Louisville to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from Louisville to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $343. If you are unable to visit Key West during the month of August, then departing from Louisville during the month February is also very affordable. Most momondo users find prices during this month for around $349.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $409 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Louisville for as low as $336 on momondo.

When to book flights from Louisville to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Key West (SDF to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Key West

Fastest flight time

4h 48m

Direct flights

None
The fastest flight from Louisville to Key West takes 4h 48m
There are no direct flights from Louisville to Key West. There are no popular flight routes from Louisville to Key West.
Search flight deals

  • How far is Louisville Intl to Key West by plane?

    Louisville Intl and Key West are 973.5 mi apart from one another. In terms of flight time, this usually takes a little over 4h 48m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Key West Airport?

    Prices for flights from Louisville Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Key West Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Louisville to Key West?

Best airlines flying from Louisville to Key West

Compare and see reviews for airlines that fly from Louisville to Key West with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $258Free CancellationRating
7.4
9,308 reviews
Search United Airlines flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,294 reviews
Search American Airlines flights
DeltaPriceFrom $258Free CancellationRating
7.9
8,206 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Key West?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Key West. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Key West with flexible booking policies on momondo?

All flight searches from Louisville to Key West on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Louisville.

I’m not ready to book a flight from Louisville to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Louisville and alert you when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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