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Cheap flights from Louisville to Key West from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Key West departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:55 pm - 6:32 pm
SDF
-
EYW
23h 37m
1 stop
Multiple Airlines Logo
1:14 pm - 11:30 am
EYW
-
SDF
22h 16m
2 stops
$234Multiple Airlines
Thu, May 28 - Tue, Jun 2
Multiple Airlines Logo
6:55 pm - 4:58 pm
SDF
-
EYW
22h 03m
1 stop
Multiple Airlines Logo
2:51 pm - 3:39 pm
EYW
-
SDF
24h 48m
1 stop
$240Multiple Airlines
Sun, May 17 - Fri, May 22
Multiple Airlines Logo
10:33 am - 12:34 pm
SDF
-
EYW
26h 01m
2 stops
Multiple Airlines Logo
11:07 am - 8:36 am
EYW
-
SDF
21h 29m
1 stop
$262Multiple Airlines
Mon, May 11 - Fri, May 15
Multiple Airlines Logo
9:14 pm - 2:43 pm
SDF
-
EYW
17h 29m
1 stop
Multiple Airlines Logo
11:01 am - 6:58 pm
EYW
-
SDF
31h 57m
2 stops
$276Multiple Airlines
Thu, Apr 23 - Thu, Apr 30
Multiple Airlines Logo
6:55 pm - 4:58 pm
SDF
-
EYW
22h 03m
1 stop
Multiple Airlines Logo
1:11 pm - 8:36 am
EYW
-
SDF
19h 25m
2 stops
$282Multiple Airlines
Sun, May 17 - Fri, May 22
Allegiant Air Logo
9:14 pm - 2:43 pm
SDF
-
EYW
17h 29m
1 stop
Allegiant Air Logo
3:19 pm - 8:24 pm
EYW
-
SDF
5h 05m
1 stop
$283Allegiant Air
Thu, May 7 - Sun, May 10
Multiple Airlines Logo
7:48 pm - 12:34 pm
SDF
-
EYW
16h 46m
2 stops
Multiple Airlines Logo
11:07 am - 8:36 am
EYW
-
SDF
21h 29m
1 stop
$299Multiple Airlines
Mon, May 11 - Fri, May 15
Multiple Airlines Logo
8:28 pm - 10:24 am
SDF
-
EYW
37h 56m
2 stops
Multiple Airlines Logo
2:51 pm - 3:39 pm
EYW
-
SDF
24h 48m
1 stop
$316Multiple Airlines
Fri, May 15 - Fri, May 22
Allegiant Air Logo
9:14 pm - 2:43 pm
SDF
-
EYW
17h 29m
1 stop
Allegiant Air Logo
3:09 pm - 8:22 pm
EYW
-
SDF
5h 13m
1 stop
$320Allegiant Air
Thu, Apr 23 - Thu, Apr 30
Delta Logo
3:29 pm - 7:49 pm
SDF
-
EYW
4h 20m
1 stop
Delta Logo
6:24 pm - 12:16 am
EYW
-
SDF
5h 52m
1 stop
$323Delta
Sat, Jun 6 - Sat, Jun 13

Allegiant Air flights from Louisville to Key West

Our best Allegiant Air deals on Louisville to Key West flight tickets
Allegiant Air
May 7
SDF9:14 pmLouisville Intl
17h 29m
1 stop
EYW2:43 pmKey West
May 10
EYW3:19 pmKey West
5h 05m
1 stop
SDF8:24 pmLouisville Intl
$283
Allegiant Air
Apr 23
SDF9:14 pmLouisville Intl
17h 29m
1 stop
EYW2:43 pmKey West
Apr 30
EYW3:09 pmKey West
5h 13m
1 stop
SDF8:22 pmLouisville Intl
$320
Allegiant Air
Apr 10
SDF7:48 pmLouisville Intl
37h 20m
2 stops
EYW9:08 amKey West
Apr 12
EYW2:48 pmKey West
5h 36m
1 stop
SDF8:24 pmLouisville Intl
$856

Delta flights from Louisville to Key West

Our best Delta deals on Louisville to Key West flight tickets
Delta
Jun 6
SDF3:29 pmLouisville Intl
4h 20m
1 stop
EYW7:49 pmKey West
Jun 13
EYW6:24 pmKey West
5h 52m
1 stop
SDF12:16 amLouisville Intl
$323
Delta
May 1
SDF3:16 pmLouisville Intl
4h 24m
1 stop
EYW7:40 pmKey West
May 5
EYW6:23 pmKey West
5h 36m
1 stop
SDF11:59 pmLouisville Intl
$331
Delta
Jun 6
SDF3:29 pmLouisville Intl
4h 20m
1 stop
EYW7:49 pmKey West
Jun 13
EYW6:24 pmKey West
5h 52m
1 stop
SDF12:16 amLouisville Intl
$346

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Louisville to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 5/28

6:55 pm-6:32 pm

1 stop23h 37m

Key West

Tue 6/2

1:14 pm-11:30 am

2 stops22h 16m

$234

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sun 5/17

6:55 pm-4:58 pm

1 stop22h 03m

Key West

Fri 5/22

2:51 pm-3:39 pm

1 stop24h 48m

$240

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Mon 5/11

10:33 am-12:34 pm

2 stops26h 01m

Key West

Fri 5/15

11:07 am-8:36 am

1 stop21h 29m

$262

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 4/23

9:14 pm-2:43 pm

1 stop17h 29m

Key West

Thu 4/30

11:01 am-6:58 pm

2 stops31h 57m

$276

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sun 5/17

6:55 pm-4:58 pm

1 stop22h 03m

Key West

Fri 5/22

1:11 pm-8:36 am

2 stops19h 25m

$282

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 5/7

9:14 pm-2:43 pm

1 stop17h 29m

Key West

Sun 5/10

3:19 pm-8:24 pm

1 stop5h 05m

$283

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Mon 5/11

7:48 pm-12:34 pm

2 stops16h 46m

Key West

Fri 5/15

11:07 am-8:36 am

1 stop21h 29m

$299

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Fri 5/15

8:28 pm-10:24 am

2 stops37h 56m

Key West

Fri 5/22

2:51 pm-3:39 pm

1 stop24h 48m

$316

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 4/23

9:14 pm-2:43 pm

1 stop17h 29m

Key West

Thu 4/30

3:09 pm-8:22 pm

1 stop5h 13m

$320
Quickest round-trip

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sat 6/6

3:29 pm-7:49 pm

1 stop4h 20m

Key West

Sat 6/13

6:24 pm-12:16 am

1 stop5h 52m

$323

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Louisville to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Key West?

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from Louisville to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $343. If you are unable to visit Key West during the month of August, then departing from Louisville during the month February is also very affordable. Most momondo users find prices during this month for around $349.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $415 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Louisville for as low as $319 on momondo.

When to book flights from Louisville to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Key West (SDF to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Key West

Fastest flight time

4h 19m

Direct flights

None
The fastest flight from Louisville to Key West takes 4h 19m
There are no direct flights from Louisville to Key West. There are no popular flight routes from Louisville to Key West.
Search flight deals

Frequently asked questions about flying from Louisville to Key West

  • How far is Louisville Intl to Key West by plane?

    Louisville Intl and Key West are 973.5 mi apart from one another. In terms of flight time, this usually takes a little over 4h 19m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Key West Airport?

    Prices for flights from Louisville Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Key West Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Louisville to Key West?

Best airlines flying from Louisville to Key West

Compare and see reviews for airlines that fly from Louisville to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,556 reviews
Search American Airlines flights
DeltaPriceFrom $258Free CancellationRating
7.9
8,383 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Key West?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Key West. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Key West with flexible booking policies on momondo?

All flight searches from Louisville to Key West on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Louisville.

I’m not ready to book a flight from Louisville to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Louisville and alert you when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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