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Cheap flights from Louisville to Key West from $134

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Key West departing on 12/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Key West

Cheap round-trip flights

Logo
8:23 am - 9:07 amSDF-EYW
24h 44m2 stops
Logo
2:18 pm - 8:35 amEYW-SDF
18h 17m1 stop
$241
Find Deal
Mon, Sep 29 - Fri, Oct 3
Delta Logo
7:09 am - 1:02 pmSDF-EYW
5h 53m1 stop
Delta Logo
6:17 pm - 12:01 amEYW-SDF
5h 44m1 stop
$283Delta
Find Deal
Sat, Oct 25 - Sat, Nov 1
American Airlines Logo
9:44 am - 4:18 pmSDF-EYW
6h 34m1 stop
American Airlines Logo
7:52 pm - 12:36 amEYW-SDF
4h 44m1 stop
$284American Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 1
Logo
2:26 pm - 10:24 amSDF-EYW
19h 58m1 stop
Logo
2:25 pm - 9:54 amEYW-SDF
19h 29m1 stop
$286
Find Deal
Thu, Feb 19 - Tue, Feb 24
American Airlines Logo
6:45 am - 4:27 pmSDF-EYW
9h 42m2 stops
American Airlines Logo
7:52 pm - 12:36 amEYW-SDF
4h 44m1 stop
$289American Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 1
Logo
9:12 pm - 9:01 amSDF-EYW
11h 49m1 stop
Logo
11:45 am - 9:59 amEYW-SDF
22h 14m2 stops
$302
Find Deal
Fri, Nov 7 - Tue, Nov 11
Delta Logo
12:54 pm - 8:06 pmSDF-EYW
7h 12m1 stop
Delta Logo
7:40 am - 11:49 amEYW-SDF
4h 09m1 stop
$311Delta
Find Deal
Thu, Oct 30 - Tue, Nov 4
American Airlines Logo
7:32 am - 4:13 pmSDF-EYW
8h 41m1 stop
American Airlines Logo
1:23 pm - 9:40 pmEYW-SDF
8h 17m2 stops
$316American Airlines
Find Deal
Thu, Oct 30 - Tue, Nov 4
United Airlines Logo
7:30 am - 4:07 pmSDF-EYW
8h 37m2 stops
United Airlines Logo
12:30 pm - 10:09 pmEYW-SDF
9h 39m2 stops
$646United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
2:03 pm - 2:29 pmSDF-EYW
24h 26m2 stops
United Airlines Logo
3:12 pm - 2:51 pmEYW-SDF
23h 39m2 stops
$678United Airlines
Find Deal
Mon, Sep 29 - Fri, Oct 3

American Airlines flights from Louisville to Key West

Our best American Airlines deals on Louisville to Key West flight tickets
American Airlines
Oct 25
SDF9:44 amLouisville Intl
6h 34m
1 stop
EYW4:18 pmKey West
Nov 1
EYW7:52 pmKey West
4h 44m
1 stop
SDF12:36 amLouisville Intl
$284
Find similar
American Airlines
Oct 25
SDF6:45 amLouisville Intl
9h 42m
2 stops
EYW4:27 pmKey West
Nov 1
EYW7:52 pmKey West
4h 44m
1 stop
SDF12:36 amLouisville Intl
$289
Find similar
American Airlines
Oct 30
SDF7:32 amLouisville Intl
8h 41m
1 stop
EYW4:13 pmKey West
Nov 4
EYW1:23 pmKey West
8h 17m
2 stops
SDF9:40 pmLouisville Intl
$316
Find similar

United Airlines flights from Louisville to Key West

Our best United Airlines deals on Louisville to Key West flight tickets
United Airlines
Sep 18
SDF6:15 amLouisville Intl
7h 46m
1 stop
EYW2:01 pmKey West
Sep 20
EYW3:05 pmKey West
7h 53m
1 stop
SDF10:58 pmLouisville Intl
$369
Find similar
United Airlines
Sep 18
SDF6:15 amLouisville Intl
7h 46m
1 stop
EYW2:01 pmKey West
Sep 20
EYW3:05 pmKey West
7h 53m
1 stop
SDF10:58 pmLouisville Intl
$386
Find similar
United Airlines
Mar 3
SDF7:30 amLouisville Intl
8h 37m
2 stops
EYW4:07 pmKey West
Mar 7
EYW12:30 pmKey West
9h 39m
2 stops
SDF10:09 pmLouisville Intl
$646
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Louisville to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Mon 9/29

8:23 am-9:07 am

2 stops24h 44m

Key West

Fri 10/3

2:18 pm-8:35 am

1 stop18h 17m

$241

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sat 10/25

7:09 am-1:02 pm

1 stop5h 53m

Key West

Sat 11/1

6:17 pm-12:01 am

1 stop5h 44m

$283

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sat 10/25

9:44 am-4:18 pm

1 stop6h 34m

Key West

Sat 11/1

7:52 pm-12:36 am

1 stop4h 44m

$284

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 2/19

2:26 pm-10:24 am

1 stop19h 58m

Key West

Tue 2/24

2:25 pm-9:54 am

1 stop19h 29m

$286

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Sat 10/25

6:45 am-4:27 pm

2 stops9h 42m

Key West

Sat 11/1

7:52 pm-12:36 am

1 stop4h 44m

$289

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Fri 11/7

9:12 pm-9:01 am

1 stop11h 49m

Key West

Tue 11/11

11:45 am-9:59 am

2 stops22h 14m

$302

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 10/30

12:54 pm-8:06 pm

1 stop7h 12m

Key West

Tue 11/4

7:40 am-11:49 am

1 stop4h 09m

$311

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Thu 10/30

7:32 am-4:13 pm

1 stop8h 41m

Key West

Tue 11/4

1:23 pm-9:40 pm

2 stops8h 17m

$316

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Tue 3/3

7:30 am-4:07 pm

2 stops8h 37m

Key West

Sat 3/7

12:30 pm-10:09 pm

2 stops9h 39m

$646

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Mon 9/29

2:03 pm-2:29 pm

2 stops24h 26m

Key West

Fri 10/3

3:12 pm-2:51 pm

2 stops23h 39m

$678

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Louisville to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from Louisville to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $331. If you are unable to visit Key West during the month of August, then departing from Louisville during the month January is also very affordable. Most momondo users find prices during this month for around $390.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Louisville is on a Saturday. momondo users have found tickets for Saturday departures for as low as $373. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Louisville to Key West for around $482.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is at noon. momondo users have found flights departing from Louisville to Key West at noon for as low as $335. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the afternoon, with an average ticket price of $399. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $427 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Louisville for as low as $339 on momondo.

When to book flights from Louisville to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Key West (SDF to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Key West

Direct flights

None
There are no direct flights from Louisville to Key West. There are no popular flight routes from Louisville to Key West.
Search flight deals

  • How far is Louisville Intl to Key West by plane?

    Louisville Intl and Key West are 973.5 mi apart from one another. In terms of flight time, this usually takes a little over 5h 03m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Key West Airport?

    Prices for flights from Louisville Intl Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Key West Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Louisville to Key West?

Best airlines flying from Louisville to Key West

Compare and see reviews for airlines that fly from Louisville to Key West with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $258Free CancellationRating
7.4
8,931 reviews
Search United Airlines flights
DeltaPriceFrom $258Free CancellationRating
7.9
7,956 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Key West?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Louisville to Key West. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Louisville to Key West with flexible booking policies on momondo?

All flight searches from Louisville to Key West on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Louisville.

I’m not ready to book a flight from Louisville to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Louisville and alert you when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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