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Cheap flights from New York LaGuardia Airport to Florence from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from New York LaGuardia Airport to Florence departing on 5/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from New York LaGuardia Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:04 pm - 9:47 pm
LGA
-
FLO
6h 43m
1 stop
American Airlines Logo
2:35 pm - 7:59 pm
FLO
-
LGA
5h 24m
1 stop
$289American Airlines
Thu, May 14 - Tue, May 26
American Airlines Logo
7:22 pm - 12:02 am
LGA
-
FLO
4h 40m
1 stop
American Airlines Logo
2:34 pm - 6:24 pm
FLO
-
LGA
3h 50m
1 stop
$296American Airlines
Sat, Aug 8 - Sat, Aug 15
American Airlines Logo
3:04 pm - 9:47 pm
LGA
-
FLO
6h 43m
1 stop
American Airlines Logo
4:16 pm - 7:59 pm
FLO
-
LGA
3h 43m
1 stop
$329American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
6:00 am - 2:09 pm
LGA
-
FLO
8h 09m
2 stops
American Airlines Logo
11:15 am - 5:29 pm
FLO
-
LGA
6h 14m
1 stop
$389American Airlines
Sat, Aug 8 - Sat, Aug 15
American Airlines Logo
3:04 pm - 9:47 pm
LGA
-
FLO
6h 43m
1 stop
American Airlines Logo
2:35 pm - 11:44 pm
FLO
-
LGA
9h 09m
2 stops
$441American Airlines
Thu, May 14 - Tue, May 26
American Airlines Logo
3:05 pm - 9:47 pm
LGA
-
FLO
6h 42m
1 stop
American Airlines Logo
4:16 pm - 7:59 pm
FLO
-
LGA
3h 43m
1 stop
$456American Airlines
Sat, Apr 11 - Wed, Apr 15
American Airlines Logo
3:04 pm - 9:47 pm
LGA
-
FLO
6h 43m
1 stop
American Airlines Logo
4:16 pm - 7:59 pm
FLO
-
LGA
3h 43m
1 stop
$460American Airlines
Fri, Apr 17 - Mon, Apr 20
American Airlines Logo
5:30 pm - 9:47 pm
LGA
-
FLO
4h 17m
1 stop
American Airlines Logo
5:20 am - 11:29 am
FLO
-
LGA
6h 09m
2 stops
$461American Airlines
Sat, Apr 11 - Wed, Apr 15
American Airlines Logo
2:45 pm - 9:47 pm
LGA
-
FLO
7h 02m
2 stops
American Airlines Logo
4:16 pm - 7:59 pm
FLO
-
LGA
3h 43m
1 stop
$465American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
9:58 am - 2:10 pm
LGA
-
FLO
4h 12m
1 stop
American Airlines Logo
5:17 am - 9:01 am
FLO
-
LGA
3h 44m
1 stop
$467American Airlines
Fri, Jul 17 - Sun, Jul 26

American Airlines flights from New York LaGuardia Airport to Florence, South Carolina

Our best American Airlines deals on New York LaGuardia Airport to Florence, South Carolina flight tickets
American Airlines
May 14
LGA3:04 pmNew York LaGuardia
6h 43m
1 stop
FLO9:47 pmFlorence
May 26
FLO2:35 pmFlorence
5h 24m
1 stop
LGA7:59 pmNew York LaGuardia
$289
American Airlines
Aug 8
LGA7:22 pmNew York LaGuardia
4h 40m
1 stop
FLO12:02 amFlorence
Aug 15
FLO2:34 pmFlorence
3h 50m
1 stop
LGA6:24 pmNew York LaGuardia
$296
American Airlines
Apr 9
LGA3:04 pmNew York LaGuardia
6h 43m
1 stop
FLO9:47 pmFlorence
Apr 13
FLO4:16 pmFlorence
3h 43m
1 stop
LGA7:59 pmNew York LaGuardia
$329

momondo Fare Finder

 
Customize your flight search to find flights from New York LaGuardia Airport to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 5/14

3:04 pm-9:47 pm

1 stop6h 43m

Florence

Tue 5/26

2:35 pm-7:59 pm

1 stop5h 24m

$289

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 8/8

7:22 pm-12:02 am

1 stop4h 40m

Florence

Sat 8/15

2:34 pm-6:24 pm

1 stop3h 50m

$296

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 4/9

3:04 pm-9:47 pm

1 stop6h 43m

Florence

Mon 4/13

4:16 pm-7:59 pm

1 stop3h 43m

$329

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 8/8

6:00 am-2:09 pm

2 stops8h 09m

Florence

Sat 8/15

11:15 am-5:29 pm

1 stop6h 14m

$389

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 5/14

3:04 pm-9:47 pm

1 stop6h 43m

Florence

Tue 5/26

2:35 pm-11:44 pm

2 stops9h 09m

$441

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 4/11

3:05 pm-9:47 pm

1 stop6h 42m

Florence

Wed 4/15

4:16 pm-7:59 pm

1 stop3h 43m

$456

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 4/17

3:04 pm-9:47 pm

1 stop6h 43m

Florence

Mon 4/20

4:16 pm-7:59 pm

1 stop3h 43m

$460

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 4/11

5:30 pm-9:47 pm

1 stop4h 17m

Florence

Wed 4/15

5:20 am-11:29 am

2 stops6h 09m

$461

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 4/9

2:45 pm-9:47 pm

2 stops7h 02m

Florence

Mon 4/13

4:16 pm-7:59 pm

1 stop3h 43m

$465
Quickest round-trip

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 7/17

9:58 am-2:10 pm

1 stop4h 12m

Florence

Sun 7/26

5:17 am-9:01 am

1 stop3h 44m

$467

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from New York LaGuardia Airport to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from New York LaGuardia to Florence?

American Airlines is the most popular carrier operating from New York LaGuardia to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to Florence, South Carolina from New York LaGuardia Airport according to our data. American Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 5 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from New York LaGuardia Airport to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from New York LaGuardia Airport to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap New York LaGuardia Airport to Florence, South Carolina (LGA to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from New York LaGuardia Airport to Florence, South Carolina

Fastest flight time

4h 58m

Direct flights

None
The fastest flight from New York LaGuardia Airport to Florence, South Carolina takes 4h 58m
There are no direct flights from New York LaGuardia Airport to Florence, South Carolina. There are no popular flight routes from New York LaGuardia Airport to Florence, South Carolina.
Search flight deals

  • How far is New York LaGuardia to Florence by plane?

    Florence is 557.0 mi away from New York LaGuardia. Flights usually cover this in 4h 58m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from New York LaGuardia Airport to Florence Airport?

    Prices for flights from New York LaGuardia Airport to Florence Airport were last updated today.

  • How many operators does momondo search for flights from New York LaGuardia Airport to Florence Airport?

  • How old do you have to be to fly from New York LaGuardia Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from New York LaGuardia Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from New York LaGuardia Airport to Florence, South Carolina?

Best airlines flying from New York LaGuardia Airport to Florence, South Carolina

Compare and see reviews for airlines that fly from New York LaGuardia Airport to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $292Free CancellationRating
7.1
11,530 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from New York to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from New York.

Can I find flights from New York to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from New York with this policy.

How can momondo help me find flights from New York to Florence?

Once all potential New York to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from New York to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for New York to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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