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Cheap flights from New York LaGuardia Airport to Florence from $333

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from New York LaGuardia Airport to Florence departing on 10/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from New York LaGuardia Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:29 pm - 9:20 pmLGA  New York LaGuardia-FLO Florence
6h 51m1 stop Charlotte Douglas
American Airlines Logo
6:24 am - 11:05 amFLO  Florence-LGA New York LaGuardia
4h 41m1 stop Charlotte Douglas
$363American Airlines
Sun, Sep 6 - Tue, Sep 15
American Airlines Logo
4:59 pm - 10:58 pmLGA  New York LaGuardia-FLO Florence
5h 59m1 stop Charlotte Douglas
American Airlines Logo
1:43 pm - 7:52 pmFLO  Florence-LGA New York LaGuardia
6h 09m1 stop Charlotte Douglas
$363American Airlines
Wed, Sep 9 - Wed, Sep 16
American Airlines Logo
4:59 pm - 10:58 pmLGA  New York LaGuardia-FLO Florence
5h 59m1 stop Charlotte Douglas
American Airlines Logo
1:43 pm - 7:52 pmFLO  Florence-LGA New York LaGuardia
6h 09m1 stop Charlotte Douglas
$417American Airlines
Wed, Sep 9 - Wed, Sep 16
American Airlines Logo
7:29 am - 2:09 pmLGA  New York LaGuardia-FLO Florence
6h 40m1 stop Charlotte Douglas
American Airlines Logo
5:09 am - 9:02 amFLO  Florence-LGA New York LaGuardia
3h 53m1 stop Charlotte Douglas
$419American Airlines
Tue, Dec 1 - Sun, Dec 6
American Airlines Logo
6:29 pm - 11:57 pmLGA  New York LaGuardia-FLO Florence
5h 28m1 stop Charlotte Douglas
American Airlines Logo
5:09 am - 11:19 amFLO  Florence-LGA New York LaGuardia
6h 10m1 stop Charlotte Douglas
$420American Airlines
Thu, Oct 8 - Wed, Oct 14
American Airlines Logo
6:29 pm - 11:12 pmLGA  New York LaGuardia-FLO Florence
4h 43m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 6:29 pmFLO  Florence-LGA New York LaGuardia
3h 54m1 stop Charlotte Douglas
$420American Airlines
Tue, Oct 27 - Sun, Nov 1
American Airlines Logo
6:13 pm - 10:59 pmLGA  New York LaGuardia-FLO Florence
4h 46m1 stop Charlotte Douglas
American Airlines Logo
3:37 pm - 8:00 pmFLO  Florence-LGA New York LaGuardia
4h 23m1 stop Charlotte Douglas
$442American Airlines
Wed, Dec 2 - Sat, Dec 5

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American Airlines flights from New York LaGuardia Airport to Florence, South Carolina

Our best American Airlines deals on New York LaGuardia Airport to Florence, South Carolina flight tickets
American Airlines
Sep 6
LGA2:29 pmNew York LaGuardia
6h 51m
1 stop
FLO9:20 pmFlorence
Sep 15
FLO6:24 amFlorence
4h 41m
1 stop
LGA11:05 amNew York LaGuardia
$363
American Airlines
Sep 9
LGA4:59 pmNew York LaGuardia
5h 59m
1 stop
FLO10:58 pmFlorence
Sep 16
FLO1:43 pmFlorence
6h 09m
1 stop
LGA7:52 pmNew York LaGuardia
$417
American Airlines
Dec 1
LGA7:29 amNew York LaGuardia
6h 40m
1 stop
FLO2:09 pmFlorence
Dec 6
FLO5:09 amFlorence
3h 53m
1 stop
LGA9:02 amNew York LaGuardia
$419

momondo Fare Finder

 
Customize your flight search to find flights from New York LaGuardia Airport to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Sun 9/6

2:29 pm-9:20 pm

1 stop6h 51m

Florence

Tue 9/15

6:24 am-11:05 am

1 stop4h 41m

$363

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Wed 9/9

4:59 pm-10:58 pm

1 stop5h 59m

Florence

Wed 9/16

1:43 pm-7:52 pm

1 stop6h 09m

$363

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Wed 9/9

4:59 pm-10:58 pm

1 stop5h 59m

Florence

Wed 9/16

1:43 pm-7:52 pm

1 stop6h 09m

$417

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Tue 12/1

7:29 am-2:09 pm

1 stop6h 40m

Florence

Sun 12/6

5:09 am-9:02 am

1 stop3h 53m

$419

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Thu 10/8

6:29 pm-11:57 pm

1 stop5h 28m

Florence

Wed 10/14

5:09 am-11:19 am

1 stop6h 10m

$420
Quickest round-trip

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Tue 10/27

6:29 pm-11:12 pm

1 stop4h 43m

Florence

Sun 11/1

2:35 pm-6:29 pm

1 stop3h 54m

$420

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Wed 12/2

6:13 pm-10:59 pm

1 stop4h 46m

Florence

Sat 12/5

3:37 pm-8:00 pm

1 stop4h 23m

$442
Cheapest one-way

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Sat 10/10

12:25 pm-11:57 pm

2 stops11h 32m

$333
Quickest one-way

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Sat 10/10

6:29 pm-11:57 pm

1 stop5h 28m

$392

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Wed 9/2

5:00 pm-10:59 pm

1 stop5h 59m

$392

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from New York LaGuardia Airport to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from New York LaGuardia to Florence?

American Airlines is the most popular carrier operating from New York LaGuardia to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Frontier are the top three most popular airlines that fly to Florence, South Carolina from New York LaGuardia Airport according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 4 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from New York LaGuardia Airport to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from New York LaGuardia Airport to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap New York LaGuardia Airport to Florence, South Carolina (LGA to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from New York LaGuardia Airport to Florence, South Carolina

Fastest flight time

4h 30m

Direct flights

None
The fastest flight from New York LaGuardia Airport to Florence, South Carolina takes 4h 30m
There are no direct flights from New York LaGuardia Airport to Florence, South Carolina. There are no popular flight routes from New York LaGuardia Airport to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from New York LaGuardia Airport to Florence, South Carolina

  • How far is New York LaGuardia to Florence by plane?

    Florence is 557.0 mi away from New York LaGuardia. Flights usually cover this in 4h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from New York LaGuardia Airport to Florence Airport?

    Prices for flights from New York LaGuardia Airport to Florence Airport were last updated today.

  • How many operators does momondo search for flights from New York LaGuardia Airport to Florence Airport?

  • How old do you have to be to fly from New York LaGuardia Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from New York LaGuardia Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from New York LaGuardia Airport to Florence, South Carolina?

Best airlines flying from New York LaGuardia Airport to Florence, South Carolina

Compare and see reviews for airlines that fly from New York LaGuardia Airport to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $343Free CancellationRating
7.1
11,941 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from New York to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from New York.

Can I find flights from New York to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from New York with this policy.

How can momondo help me find flights from New York to Florence?

Once all potential New York to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from New York to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for New York to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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