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Cheap flights from New York LaGuardia Airport to Florence from $299

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from New York LaGuardia Airport to Florence departing on 3/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from New York LaGuardia Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:48 pm - 5:50 pm
LGA
-
FLO
5h 02m
1 stop
American Airlines Logo
6:20 pm - 11:25 pm
FLO
-
LGA
5h 05m
1 stop
$410American Airlines
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
4:16 pm - 11:57 pm
LGA
-
FLO
7h 41m
2 stops
American Airlines Logo
6:20 pm - 11:25 pm
FLO
-
LGA
5h 05m
1 stop
$415American Airlines
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
12:49 pm - 5:50 pm
LGA
-
FLO
5h 01m
1 stop
American Airlines Logo
5:16 am - 9:21 am
FLO
-
LGA
4h 05m
1 stop
$551American Airlines
Fri, Mar 13 - Sun, Mar 15
American Airlines Logo
6:59 pm - 11:57 pm
LGA
-
FLO
4h 58m
1 stop
American Airlines Logo
5:16 am - 11:21 am
FLO
-
LGA
6h 05m
2 stops
$556American Airlines
Fri, Mar 13 - Sun, Mar 15
American Airlines Logo
10:14 am - 5:50 pm
LGA
-
FLO
7h 36m
2 stops
American Airlines Logo
5:16 am - 11:21 am
FLO
-
LGA
6h 05m
2 stops
$561American Airlines
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
1:49 pm - 11:53 pm
LGA
-
FLO
10h 04m
1 stop
American Airlines Logo
4:16 pm - 11:25 pm
FLO
-
LGA
7h 09m
1 stop
$591American Airlines
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
9:59 am - 2:11 pm
LGA
-
FLO
4h 12m
1 stop
American Airlines Logo
2:36 pm - 7:59 pm
FLO
-
LGA
5h 23m
1 stop
$594American Airlines
Fri, Jul 3 - Mon, Jul 6
American Airlines Logo
9:59 am - 2:11 pm
LGA
-
FLO
4h 12m
1 stop
American Airlines Logo
5:09 am - 1:59 pm
FLO
-
LGA
8h 50m
2 stops
$599American Airlines
Fri, Jul 3 - Mon, Jul 6
American Airlines Logo
12:15 pm - 11:56 pm
LGA
-
FLO
11h 41m
2 stops
American Airlines Logo
5:09 am - 1:59 pm
FLO
-
LGA
8h 50m
2 stops
$647American Airlines
Fri, Jul 3 - Mon, Jul 6
American Airlines Logo
4:31 pm - 11:53 pm
LGA
-
FLO
7h 22m
2 stops
American Airlines Logo
5:24 am - 9:21 am
FLO
-
LGA
3h 57m
1 stop
$687American Airlines
Thu, Apr 9 - Sun, Apr 12

American Airlines flights from New York LaGuardia Airport to Florence, South Carolina

Our best American Airlines deals on New York LaGuardia Airport to Florence, South Carolina flight tickets
American Airlines
Feb 26
LGA12:48 pmNew York LaGuardia
5h 02m
1 stop
FLO5:50 pmFlorence
Mar 2
FLO6:20 pmFlorence
5h 05m
1 stop
LGA11:25 pmNew York LaGuardia
$410
American Airlines
Feb 26
LGA4:16 pmNew York LaGuardia
7h 41m
2 stops
FLO11:57 pmFlorence
Mar 2
FLO6:20 pmFlorence
5h 05m
1 stop
LGA11:25 pmNew York LaGuardia
$415
American Airlines
Feb 14
LGA6:59 pmNew York LaGuardia
4h 58m
1 stop
FLO11:57 pmFlorence
Feb 17
FLO6:15 amFlorence
5h 43m
1 stop
LGA11:58 amNew York LaGuardia
$441

momondo Fare Finder

 
Customize your flight search to find flights from New York LaGuardia Airport to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 2/26

12:48 pm-5:50 pm

1 stop5h 02m

Florence

Mon 3/2

6:20 pm-11:25 pm

1 stop5h 05m

$410

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 2/26

4:16 pm-11:57 pm

2 stops7h 41m

Florence

Mon 3/2

6:20 pm-11:25 pm

1 stop5h 05m

$415

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 3/13

12:49 pm-5:50 pm

1 stop5h 01m

Florence

Sun 3/15

5:16 am-9:21 am

1 stop4h 05m

$551

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 3/13

6:59 pm-11:57 pm

1 stop4h 58m

Florence

Sun 3/15

5:16 am-11:21 am

2 stops6h 05m

$556

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 2/26

10:14 am-5:50 pm

2 stops7h 36m

Florence

Mon 3/2

5:16 am-11:21 am

2 stops6h 05m

$561

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 4/9

1:49 pm-11:53 pm

1 stop10h 04m

Florence

Sun 4/12

4:16 pm-11:25 pm

1 stop7h 09m

$591

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 7/3

9:59 am-2:11 pm

1 stop4h 12m

Florence

Mon 7/6

2:36 pm-7:59 pm

1 stop5h 23m

$594

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 7/3

9:59 am-2:11 pm

1 stop4h 12m

Florence

Mon 7/6

5:09 am-1:59 pm

2 stops8h 50m

$599

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 7/3

12:15 pm-11:56 pm

2 stops11h 41m

Florence

Mon 7/6

5:09 am-1:59 pm

2 stops8h 50m

$647

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 4/9

4:31 pm-11:53 pm

2 stops7h 22m

Florence

Sun 4/12

5:24 am-9:21 am

1 stop3h 57m

$687

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from New York LaGuardia Airport to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from New York LaGuardia to Florence?

American Airlines is the most popular carrier operating from New York LaGuardia to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to Florence, South Carolina from New York LaGuardia Airport according to our data. American Airlines is the first choice among our users, with 31% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 5 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from New York LaGuardia Airport to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from New York LaGuardia Airport to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap New York LaGuardia Airport to Florence, South Carolina (LGA to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from New York LaGuardia Airport to Florence, South Carolina

Fastest flight time

4h 12m

Direct flights

None
The fastest flight from New York LaGuardia Airport to Florence, South Carolina takes 4h 12m
There are no direct flights from New York LaGuardia Airport to Florence, South Carolina. There are no popular flight routes from New York LaGuardia Airport to Florence, South Carolina.
Search flight deals

  • How far is New York LaGuardia to Florence by plane?

    Florence is 557.0 mi away from New York LaGuardia. Flights usually cover this in 4h 12m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from New York LaGuardia Airport to Florence Airport?

    Prices for flights from New York LaGuardia Airport to Florence Airport were last updated today.

  • How many operators does momondo search for flights from New York LaGuardia Airport to Florence Airport?

  • How old do you have to be to fly from New York LaGuardia Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from New York LaGuardia Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from New York LaGuardia Airport to Florence, South Carolina?

Best airlines flying from New York LaGuardia Airport to Florence, South Carolina

Compare and see reviews for airlines that fly from New York LaGuardia Airport to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $272Free CancellationRating
7.2
11,275 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Darlington
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from New York to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from New York.

Can I find flights from New York to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from New York with this policy.

How can momondo help me find flights from New York to Florence?

Once all potential New York to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from New York to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for New York to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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