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Cheap flights from La Crosse to Buffalo from $356

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to Buffalo departing on 9/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from La Crosse to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:53 am - 5:04 pm
LSE
-
BUF
4h 11m
1 stop
American Airlines Logo
6:56 pm - 12:20 am
BUF
-
LSE
6h 24m
1 stop
$356American Airlines
Sun, Sep 6 - Sun, Sep 13
American Airlines Logo
6:02 am - 2:26 pm
LSE
-
BUF
7h 24m
2 stops
American Airlines Logo
7:59 am - 11:22 am
BUF
-
LSE
4h 23m
1 stop
$361American Airlines
Sun, Sep 6 - Sun, Sep 13
American Airlines Logo
6:02 am - 2:26 pm
LSE
-
BUF
7h 24m
2 stops
American Airlines Logo
5:37 am - 11:22 am
BUF
-
LSE
6h 45m
2 stops
$366American Airlines
Sun, Sep 6 - Sun, Sep 13
American Airlines Logo
5:20 pm - 12:02 am
LSE
-
BUF
5h 42m
1 stop
American Airlines Logo
6:09 pm - 12:22 am
BUF
-
LSE
7h 13m
1 stop
$396American Airlines
Wed, Aug 19 - Tue, Aug 25
American Airlines Logo
5:20 pm - 12:02 am
LSE
-
BUF
5h 42m
1 stop
American Airlines Logo
5:40 pm - 12:22 am
BUF
-
LSE
7h 42m
2 stops
$402American Airlines
Wed, Aug 19 - Tue, Aug 25
American Airlines Logo
12:01 pm - 5:00 pm
LSE
-
BUF
3h 59m
1 stop
American Airlines Logo
6:09 pm - 12:22 am
BUF
-
LSE
7h 13m
1 stop
$432American Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
12:01 pm - 5:00 pm
LSE
-
BUF
3h 59m
1 stop
American Airlines Logo
5:00 am - 11:31 am
BUF
-
LSE
7h 31m
2 stops
$438American Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
11:53 am - 5:04 pm
LSE
-
BUF
4h 11m
1 stop
American Airlines Logo
6:09 pm - 12:22 am
BUF
-
LSE
7h 13m
1 stop
$482American Airlines
Sun, Aug 16 - Tue, Aug 25
American Airlines Logo
5:26 pm - 12:02 am
LSE
-
BUF
5h 36m
1 stop
American Airlines Logo
5:40 pm - 12:22 am
BUF
-
LSE
7h 42m
2 stops
$488American Airlines
Sun, Aug 16 - Tue, Aug 25
American Airlines Logo
5:20 pm - 5:29 pm
LSE
-
BUF
23h 09m
2 stops
American Airlines Logo
5:00 am - 11:31 am
BUF
-
LSE
7h 31m
2 stops
$555American Airlines
Wed, Aug 19 - Tue, Aug 25

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American Airlines flights from La Crosse to Buffalo

Our best American Airlines deals on La Crosse to Buffalo flight tickets
American Airlines
Sep 6
LSE11:53 amLa Crosse
4h 11m
1 stop
BUF5:04 pmBuffalo
Sep 13
BUF6:56 pmBuffalo
6h 24m
1 stop
LSE12:20 amLa Crosse
$356
American Airlines
Sep 6
LSE6:02 amLa Crosse
7h 24m
2 stops
BUF2:26 pmBuffalo
Sep 13
BUF7:59 amBuffalo
4h 23m
1 stop
LSE11:22 amLa Crosse
$361
American Airlines
Sep 6
LSE6:02 amLa Crosse
7h 24m
2 stops
BUF2:26 pmBuffalo
Sep 13
BUF5:37 amBuffalo
6h 45m
2 stops
LSE11:22 amLa Crosse
$366

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from La Crosse to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Sun 9/6

11:53 am-5:04 pm

1 stop4h 11m

Buffalo

Sun 9/13

6:56 pm-12:20 am

1 stop6h 24m

$356

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Sun 9/6

6:02 am-2:26 pm

2 stops7h 24m

Buffalo

Sun 9/13

7:59 am-11:22 am

1 stop4h 23m

$361

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Sun 9/6

6:02 am-2:26 pm

2 stops7h 24m

Buffalo

Sun 9/13

5:37 am-11:22 am

2 stops6h 45m

$366

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Wed 8/19

5:20 pm-12:02 am

1 stop5h 42m

Buffalo

Tue 8/25

6:09 pm-12:22 am

1 stop7h 13m

$396

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Wed 8/19

5:20 pm-12:02 am

1 stop5h 42m

Buffalo

Tue 8/25

5:40 pm-12:22 am

2 stops7h 42m

$402

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Tue 8/18

12:01 pm-5:00 pm

1 stop3h 59m

Buffalo

Tue 8/25

6:09 pm-12:22 am

1 stop7h 13m

$432

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Tue 8/18

12:01 pm-5:00 pm

1 stop3h 59m

Buffalo

Tue 8/25

5:00 am-11:31 am

2 stops7h 31m

$438

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Sun 8/16

11:53 am-5:04 pm

1 stop4h 11m

Buffalo

Tue 8/25

6:09 pm-12:22 am

1 stop7h 13m

$482

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Sun 8/16

5:26 pm-12:02 am

1 stop5h 36m

Buffalo

Tue 8/25

5:40 pm-12:22 am

2 stops7h 42m

$488

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Wed 8/19

5:20 pm-5:29 pm

2 stops23h 09m

Buffalo

Tue 8/25

5:00 am-11:31 am

2 stops7h 31m

$555

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from La Crosse to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from La Crosse to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap La Crosse to Buffalo (LSE to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to Buffalo

Fastest flight time

3h 59m

Direct flights

None
The fastest flight from La Crosse to Buffalo takes 3h 59m
There are no direct flights from La Crosse to Buffalo. There are no popular flight routes from La Crosse to Buffalo.
Search flight deals

Frequently asked questions about flying from La Crosse to Buffalo

  • How far is La Crosse to Buffalo by plane?

    La Crosse and Buffalo are 623.3 mi apart from one another. A reasonable flight in good conditions will take 3h 59m.

  • When did momondo last update prices for flights from La Crosse Airport to Buffalo Airport?

    Prices for flights from La Crosse Airport to Buffalo Airport are refreshed on a daily basis.

  • How old do you have to be to fly from La Crosse Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from La Crosse Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Frequently asked questions about flying from La Crosse to Buffalo

  • How do I get Price Alerts for flights from La Crosse to Buffalo?

    Confirm your travel details to search for the latest offers for flights from La Crosse to Buffalo. While browsing offers there will be the option to toggle “Price Alerts”. You’ll then receive updates when prices for the flight route increase or decrease.

  • How can I save money on flights from La Crosse to Buffalo with momondo?

    Plan your trips smart with the “Price Forecast” feature, which uses flight data to help you pick the best days to fly for the lowest fares. Our “Price Calendar” helps you get the most for your money by showing you when it’s most advantageous to fly. Curate your own travel experiences for less with “Explore”. Expert travel hacks to fuel your next adventure are a click away with “Discover” by momondo. Set up our “Price Alerts” to track fare changes and book when prices are at their lowest point.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Williamsville
Orchard Park
Grand Island
Bowmansville
West Seneca
Lockport
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to Buffalo?

Finding the right flight to Buffalo from La Crosse is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Buffalo quick and easy, saving you time and money.

Can I find flights from La Crosse to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from La Crosse which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from La Crosse to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from La Crosse. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from La Crosse to Buffalo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from La Crosse to Buffalo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Buffalo and let you know when they change.

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Tue 8/25
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