How many flights depart from Knoxville to Ohio on average per week?

As of September 2026, 9 flights take off from Knoxville and land in Ohio each week. The most common flight departure day for this route is Mon, with 100% of weekly flights taking off on this day.

What airlines fly to Ohio?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Ohio from Knoxville according to our data. American Airlines is the first choice among our users, with 56% of people opting to fly with this airline when traveling to Ohio. Keep in mind that there are 3 different airlines that fly to Ohio on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Ohio?

Allegiant Air, Southwest, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Ohio

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Ohio?

Prices for flights from Knoxville McGhee Tyson Airport to Ohio were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Ohio?

There are 4 operators available for flights from Knoxville McGhee Tyson Airport to Ohio as of September 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Ohio?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Ohio.

What documentation or ID do you need to fly to Ohio?

The travel and health documents required for your trip to Ohio can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Ohio. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$106 Cheap Flights from Knoxville to Ohio in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Ohio

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:00 am - 9:25 pmTYS Knoxville McGhee Tyson-PIT Pittsburgh

10h 25m1 stop Jacksonville

3:09 pm - 8:31 pmPIT Pittsburgh-TYS Knoxville McGhee Tyson

5h 22m1 stop Jacksonville

$221Multiple Airlines

Thu, Dec 3 - Sun, Dec 6

7:00 am - 12:19 amTYS Knoxville McGhee Tyson-CLE Cleveland Hopkins Intl

17h 19m1 stop Orlando

9:59 pm - 11:14 amCLE Cleveland Hopkins Intl-TYS Knoxville McGhee Tyson

13h 15m1 stop Orlando

$227Multiple Airlines

Fri, Oct 16 - Sun, Oct 18

7:15 am - 11:58 amTYS Knoxville McGhee Tyson-CMH Columbus

4h 43m1 stop Washington, D.C. Reagan-National

6:00 am - 10:25 amCMH Columbus-TYS Knoxville McGhee Tyson

4h 25m1 stop Washington, D.C. Reagan-National

$273American Airlines

Thu, Oct 1 - Mon, Oct 5

7:30 am - 12:16 pmTYS Knoxville McGhee Tyson-CLE Cleveland Hopkins Intl

4h 46m1 stop Chicago O'Hare Intl

7:38 pm - 11:55 pmCLE Cleveland Hopkins Intl-TYS Knoxville McGhee Tyson

4h 17m1 stop Charlotte Douglas

$273American Airlines

Thu, Oct 15 - Mon, Oct 19

5:40 am - 9:58 amTYS Knoxville McGhee Tyson-CMH Columbus

4h 18m1 stop Atlanta Hartsfield-Jackson

2:31 pm - 8:08 pmCMH Columbus-TYS Knoxville McGhee Tyson

5h 37m1 stop Atlanta Hartsfield-Jackson

$273Delta

Thu, Nov 5 - Sat, Nov 7

12:23 pm - 6:10 pmTYS Knoxville McGhee Tyson-CMH Columbus

5h 47m1 stop Atlanta Hartsfield-Jackson

3:10 pm - 8:15 pmCMH Columbus-TYS Knoxville McGhee Tyson

5h 05m1 stop Atlanta Hartsfield-Jackson

$273Delta

Thu, Oct 1 - Mon, Oct 5

7:25 pm - 11:05 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

3h 40m1 stop Nashville Intl

4:50 pm - 9:40 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

4h 50m1 stop Baltimore/Washington

$287Southwest

Thu, Oct 29 - Mon, Nov 2

7:15 am - 9:45 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

14h 30m2 stops Nashville Intl Chicago Midway

4:50 pm - 9:40 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

4h 50m1 stop Baltimore/Washington

$298Southwest

Thu, Oct 29 - Mon, Nov 2

6:45 am - 2:14 pmTYS Knoxville McGhee Tyson-PIT Pittsburgh

7h 29m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

8:00 pm - 11:59 pmPIT Pittsburgh-TYS Knoxville McGhee Tyson

3h 59m1 stop Washington, D.C. Dulles Intl

$321United Airlines

Wed, Nov 4 - Mon, Nov 9

5:40 pm - 11:59 pmTYS Knoxville McGhee Tyson-PIT Pittsburgh

6h 19m1 stop Chicago O'Hare Intl

8:00 pm - 11:59 pmPIT Pittsburgh-TYS Knoxville McGhee Tyson

3h 59m1 stop Washington, D.C. Dulles Intl

$321United Airlines

Fri, Oct 30 - Mon, Nov 2

Cheap last minute flights

Enter your travel dates to find the best prices.

4:18 pm - 9:07 amTYS Knoxville McGhee Tyson-CLE Cleveland Hopkins Intl

16h 49m1 stop Orlando

6:20 am - 8:39 pmCLE Cleveland Hopkins Intl-TYS Knoxville McGhee Tyson

14h 19m1 stop Orlando

$289Multiple Airlines

Mon, Sep 14 - Mon, Sep 21

4:18 pm - 9:07 amTYS Knoxville McGhee Tyson-CLE Cleveland Hopkins Intl

16h 49m1 stop Orlando

3:45 pm - 10:04 amCLE Cleveland Hopkins Intl-TYS Knoxville McGhee Tyson

42h 19m2 stops Atlanta Hartsfield-Jackson Fort Lauderdale

$316Multiple Airlines

Mon, Sep 14 - Mon, Sep 21

11:20 am - 6:51 pmTYS Knoxville McGhee Tyson-CAK Akron/Canton

7h 31m1 stop Chicago O'Hare Intl

9:46 am - 4:16 pmCAK Akron/Canton-TYS Knoxville McGhee Tyson

6h 30m1 stop Charlotte Douglas

$389American Airlines

Fri, Sep 11 - Sun, Sep 13

1:10 pm - 6:30 pmTYS Knoxville McGhee Tyson-PIT Pittsburgh

5h 20m1 stop Washington, D.C. Dulles Intl

6:10 am - 10:37 amPIT Pittsburgh-TYS Knoxville McGhee Tyson

4h 27m1 stop Washington, D.C. Dulles Intl

$484United Airlines

Wed, Sep 9 - Sat, Sep 12

7:00 am - 3:10 pmTYS Knoxville McGhee Tyson-PIT Pittsburgh

8h 10m2 stops Nashville Intl Chicago Midway

9:40 am - 2:40 pmPIT Pittsburgh-TYS Knoxville McGhee Tyson

5h 00m1 stop Orlando

$489Southwest

Wed, Sep 9 - Sat, Sep 12

7:00 am - 3:10 pmTYS Knoxville McGhee Tyson-PIT Pittsburgh

8h 10m2 stops Nashville Intl Chicago Midway

6:10 am - 2:40 pmPIT Pittsburgh-TYS Knoxville McGhee Tyson

8h 30m2 stops Baltimore/Washington Orlando

$494Southwest

Wed, Sep 9 - Sat, Sep 12

6:00 am - 3:08 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

9h 08m1 stop Dallas/Fort Worth

12:55 pm - 8:01 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

7h 06m1 stop Philadelphia

$529American Airlines

Thu, Sep 10 - Thu, Sep 17

7:33 am - 9:15 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 42mnonstop

8:35 am - 10:18 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 43mnonstop

$529Delta

Thu, Sep 10 - Thu, Sep 17

7:33 am - 9:15 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 42mnonstop

8:35 am - 10:18 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 43mnonstop

$529Delta

Sat, Sep 12 - Sun, Sep 13

7:00 am - 1:09 pmTYS Knoxville McGhee Tyson-CVG Cincinnati Cinci./N. Kentucky

6h 09m1 stop Chicago O'Hare Intl

9:00 am - 1:18 pmCVG Cincinnati Cinci./N. Kentucky-TYS Knoxville McGhee Tyson

4h 18m1 stop Chicago O'Hare Intl

$637United Airlines

Thu, Sep 10 - Sun, Sep 13

Cheap direct flights

Enter your travel dates to find the best prices.

11:45 am - 1:29 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 44mnonstop

6:10 pm - 7:49 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 39mnonstop

$359Delta

Thu, Oct 29 - Mon, Nov 2

11:45 am - 1:29 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 44mnonstop

4:44 pm - 6:24 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 40mnonstop

$359Delta

Fri, Oct 23 - Sun, Oct 25

11:45 am - 1:29 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 44mnonstop

4:44 pm - 6:24 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 40mnonstop

$359Delta

Thu, Oct 8 - Mon, Oct 12

11:45 am - 1:29 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 44mnonstop

8:05 pm - 9:44 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 39mnonstop

$365Delta

Thu, Sep 24 - Sun, Sep 27

7:26 am - 9:10 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 44mnonstop

7:55 pm - 9:37 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 42mnonstop

$379Delta

Fri, Oct 9 - Tue, Oct 13

7:26 am - 9:10 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 44mnonstop

7:55 pm - 9:37 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 42mnonstop

$379Delta

Fri, Oct 9 - Mon, Oct 12

5:18 pm - 7:01 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 43mnonstop

8:40 am - 10:20 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 40mnonstop

$379Delta

Fri, Oct 16 - Mon, Oct 19

11:49 am - 1:39 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 50mnonstop

7:58 pm - 9:33 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 35mnonstop

$379Delta

Thu, Dec 10 - Mon, Dec 14

11:30 am - 1:14 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 44mnonstop

7:55 pm - 9:34 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 39mnonstop

$379Delta

Tue, Jan 19 - Sun, Jan 24

7:25 am - 9:14 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 49mnonstop

7:50 pm - 9:25 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 35mnonstop

$379Delta

Mon, Dec 21 - Thu, Dec 31

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Delta flights from Knoxville to Ohio

Our best Delta deals on Knoxville to Ohio flight tickets

Delta

Dec 4

TYS12:32 pmKnoxville McGhee Tyson

3h 32m

1 stop

PIT4:04 pmPittsburgh

Dec 7

PIT8:00 amPittsburgh

5h 49m

1 stop

TYS1:49 pmKnoxville McGhee Tyson

$284

Delta

Dec 4

TYS4:01 pmKnoxville McGhee Tyson

6h 29m

1 stop

PIT10:30 pmPittsburgh

Dec 6

PIT6:00 amPittsburgh

5h 27m

1 stop

TYS11:27 amKnoxville McGhee Tyson

$331

Delta

Oct 14

TYS5:40 amKnoxville McGhee Tyson

4h 31m

1 stop

CLE10:11 amCleveland Hopkins Intl

Oct 15

CLE6:00 amCleveland Hopkins Intl

3h 34m

1 stop

TYS9:34 amKnoxville McGhee Tyson

$355

Southwest flights from Knoxville to Ohio

Our best Southwest deals on Knoxville to Ohio flight tickets

Southwest

Oct 29

TYS7:25 pmKnoxville McGhee Tyson

3h 40m

1 stop

DTW11:05 pmDetroit Metropolitan Wayne County

Nov 2

DTW4:50 pmDetroit Metropolitan Wayne County

4h 50m

1 stop

TYS9:40 pmKnoxville McGhee Tyson

$287

Southwest

Dec 4

TYS7:55 amKnoxville McGhee Tyson

4h 05m

1 stop

CLE12:00 pmCleveland Hopkins Intl

Dec 7

CLE6:05 amCleveland Hopkins Intl

6h 15m

1 stop

TYS12:20 pmKnoxville McGhee Tyson

$304

Southwest

Oct 27

TYS8:20 amKnoxville McGhee Tyson

10h 15m

2 stops

PIT6:35 pmPittsburgh

Oct 31

PIT6:25 amPittsburgh

3h 25m

1 stop

TYS9:50 amKnoxville McGhee Tyson

$322

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvillePittsburgh

TYS Knoxville McGhee Tyson - PIT Pittsburgh

TYSPIT

Knoxville McGhee Tyson

Thu 12/3

11:00 am-9:25 pm

1 stop10h 25m

Pittsburgh

Sun 12/6

3:09 pm-8:31 pm

1 stop5h 22m

$221

KnoxvilleCleveland

TYS Knoxville McGhee Tyson - CLE Cleveland Hopkins Intl

TYSCLE

Knoxville McGhee Tyson

Fri 10/16

7:00 am-12:19 am

1 stop17h 19m

Cleveland Hopkins Intl

Sun 10/18

9:59 pm-11:14 am

1 stop13h 15m

$227

KnoxvilleColumbus

TYS Knoxville McGhee Tyson - CMH Columbus

TYSCMH

Knoxville McGhee Tyson

Thu 10/1

7:15 am-11:58 am

1 stop4h 43m

Columbus

Mon 10/5

6:00 am-10:25 am

1 stop4h 25m

$273

KnoxvilleCleveland

TYS Knoxville McGhee Tyson - CLE Cleveland Hopkins Intl

TYSCLE

Knoxville McGhee Tyson

Thu 10/15

7:30 am-12:16 pm

1 stop4h 46m

Cleveland Hopkins Intl

Mon 10/19

7:38 pm-11:55 pm

1 stop4h 17m

$273

KnoxvilleColumbus

TYS Knoxville McGhee Tyson - CMH Columbus

TYSCMH

Knoxville McGhee Tyson

Thu 11/5

5:40 am-9:58 am

1 stop4h 18m

Columbus

Sat 11/7

2:31 pm-8:08 pm

1 stop5h 37m

$273

KnoxvilleColumbus

TYS Knoxville McGhee Tyson - CMH Columbus

TYSCMH

Knoxville McGhee Tyson

Thu 10/1

12:23 pm-6:10 pm

1 stop5h 47m

Columbus

Mon 10/5

3:10 pm-8:15 pm

1 stop5h 05m

$273

Quickest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/29

7:25 pm-11:05 pm

1 stop3h 40m

Detroit Metropolitan Wayne County

Mon 11/2

4:50 pm-9:40 pm

1 stop4h 50m

$287

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/29

7:15 am-9:45 pm

2 stops14h 30m

Detroit Metropolitan Wayne County

Mon 11/2

4:50 pm-9:40 pm

1 stop4h 50m

$298

KnoxvillePittsburgh

TYS Knoxville McGhee Tyson - PIT Pittsburgh

TYSPIT

Knoxville McGhee Tyson

Wed 11/4

6:45 am-2:14 pm

2 stops7h 29m

Pittsburgh

Mon 11/9

8:00 pm-11:59 pm

1 stop3h 59m

$321

KnoxvillePittsburgh

TYS Knoxville McGhee Tyson - PIT Pittsburgh

TYSPIT

Knoxville McGhee Tyson

Fri 10/30

5:40 pm-11:59 pm

1 stop6h 19m

Pittsburgh

Mon 11/2

8:00 pm-11:59 pm

1 stop3h 59m

$321

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Ohio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Ohio?

In general, February is the cheapest month to fly from Knoxville to Ohio. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you are unable to visit Ohio during the month of February, then departing from Knoxville during the month July is also very affordable. Most momondo users find prices during this month for around $336.

Cheap Knoxville to Ohio flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Ohio

Best Price Found	$106
Fastest flight time	1h 42m
Direct flights	Every day
Airports in Ohio	108 airports

The best one-way flight to Ohio from Knoxville in the past 72 hours is $106. The best round-trip flight deal from Knoxville to Ohio found on momondo in the last 72 hours is $221.

The fastest flight from Knoxville to Ohio takes 1h 42m

Direct flights go from Knoxville to Ohio every day.

There are 108 airports in Ohio. From Knoxville there are direct flights to Detroit Metropolitan Wayne County (DTW).

Search flight deals

Frequently asked questions about flying from Knoxville to Ohio

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Ohio?
Prices for flights from Knoxville McGhee Tyson Airport to Ohio were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Ohio?
There are 4 operators available for flights from Knoxville McGhee Tyson Airport to Ohio as of September 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Ohio?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Ohio.
What documentation or ID do you need to fly to Ohio?
The travel and health documents required for your trip to Ohio can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Ohio. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Ohio

Compare and see reviews for airlines that fly from Knoxville to Ohio with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.1 12,040 reviews	Search American Airlines flights
Southwest	PriceFrom $230	Free Cancellation	Rating 8.0 4,196 reviews	Search Southwest flights
Delta	PriceFrom $238	Free Cancellation	Rating 7.8 8,548 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Ohio?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Ohio from Knoxville.

Can I find flights from Knoxville to Ohio with flexible booking policies on momondo?

Yes. All flights to Ohio from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to Ohio?

Once all potential Knoxville to Ohio flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Ohio right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Ohio now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Ohio and let you know when they change.