What airlines fly to Mexico?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Mexico from Knoxville according to our data. American Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to Mexico. Keep in mind that there are 5 different airlines that fly to Mexico on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Mexico?

Southwest and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Mexico

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Mexico?

Prices for flights from Knoxville McGhee Tyson Airport to Mexico were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Mexico?

As of August 2026, there are 5 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Mexico.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Mexico?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Mexico.

What documentation or ID do you need to fly to Mexico?

The travel and health documents required for your trip to Mexico can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mexico. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$179 Cheap Flights from Knoxville to Mexico in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Mexico

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:20 am - 7:45 pmTYS Knoxville McGhee Tyson-MEX Mexico City Benito Juarez

13h 25m1 stop Orlando

11:05 am - 8:39 pmMEX Mexico City Benito Juarez-TYS Knoxville McGhee Tyson

7h 34m1 stop Orlando

$422Multiple Airlines

Fri, Sep 11 - Mon, Sep 14

8:00 am - 10:15 pmTYS Knoxville McGhee Tyson-MEX Mexico City Benito Juarez

16h 15m2 stops Austin Bergstrom Monterrey Gen Mariano Escobedo

11:05 am - 8:39 pmMEX Mexico City Benito Juarez-TYS Knoxville McGhee Tyson

7h 34m1 stop Orlando

$448Multiple Airlines

Fri, Sep 11 - Mon, Sep 14

7:55 am - 5:00 pmTYS Knoxville McGhee Tyson-CUN Cancun

9h 05m1 stop Baltimore/Washington

12:35 pm - 8:45 pmCUN Cancun-TYS Knoxville McGhee Tyson

8h 10m1 stop Baltimore/Washington

$474Southwest

Fri, Dec 4 - Tue, Dec 8

8:10 am - 1:15 pmTYS Knoxville McGhee Tyson-CUN Cancun

6h 05m1 stop Baltimore/Washington

1:00 pm - 9:30 pmCUN Cancun-TYS Knoxville McGhee Tyson

7h 30m1 stop Baltimore/Washington

$485Southwest

Sat, Oct 24 - Thu, Oct 29

7:00 am - 11:34 amTYS Knoxville McGhee Tyson-CUN Cancun

5h 34m1 stop Miami

12:45 pm - 10:59 pmCUN Cancun-TYS Knoxville McGhee Tyson

9h 14m1 stop Miami

$520American Airlines

Wed, Sep 30 - Wed, Oct 7

6:15 am - 1:35 pmTYS Knoxville McGhee Tyson-CUN Cancun

8h 20m1 stop Charlotte Douglas

2:07 pm - 11:07 pmCUN Cancun-TYS Knoxville McGhee Tyson

8h 00m1 stop Miami

$562American Airlines

Mon, Sep 14 - Fri, Sep 18

5:45 am - 11:05 amTYS Knoxville McGhee Tyson-CUN Cancun

6h 20m1 stop Washington, D.C. Dulles Intl

12:11 pm - 8:49 pmCUN Cancun-TYS Knoxville McGhee Tyson

7h 38m1 stop Chicago O'Hare Intl

$568United Airlines

Wed, Sep 30 - Wed, Oct 7

7:10 am - 12:32 amTYS Knoxville McGhee Tyson-CUN Cancun

17h 22m2 stops Atlanta Hartsfield-Jackson Mexico City Benito Juarez

9:24 am - 10:22 pmCUN Cancun-TYS Knoxville McGhee Tyson

12h 58m2 stops Mexico City Benito Juarez Atlanta Hartsfield-Jackson

$568Delta

Mon, Nov 16 - Wed, Nov 25

5:40 am - 2:25 pmTYS Knoxville McGhee Tyson-CUN Cancun

9h 45m1 stop Atlanta Hartsfield-Jackson

8:00 am - 1:31 pmCUN Cancun-TYS Knoxville McGhee Tyson

5h 31m1 stop Atlanta Hartsfield-Jackson

$568Delta

Wed, Oct 28 - Thu, Nov 5

7:25 pm - 2:42 pmTYS Knoxville McGhee Tyson-CZM Cozumel Intl

20h 17m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

3:52 pm - 9:45 amCZM Cozumel Intl-TYS Knoxville McGhee Tyson

16h 53m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$585United Airlines

Tue, Sep 29 - Tue, Oct 6

Cheap last minute flights

Enter your travel dates to find the best prices.

1:26 pm - 10:15 pmTYS Knoxville McGhee Tyson-MEX Mexico City Benito Juarez

10h 49m1 stop Houston Hobby

10:50 pm - 12:05 pmMEX Mexico City Benito Juarez-TYS Knoxville McGhee Tyson

35h 15m2 stops Guadalajara Miguel Hidal Orlando

$411Multiple Airlines

Fri, Aug 21 - Tue, Aug 25

1:26 pm - 10:15 pmTYS Knoxville McGhee Tyson-MEX Mexico City Benito Juarez

10h 49m1 stop Houston Hobby

6:20 am - 6:43 pmMEX Mexico City Benito Juarez-TYS Knoxville McGhee Tyson

10h 23m1 stop Houston George Bush Intcntl

$428Multiple Airlines

Fri, Aug 21 - Mon, Aug 24

6:03 am - 11:07 amTYS Knoxville McGhee Tyson-CUN Cancun

6h 04m1 stop Dallas/Fort Worth

1:14 pm - 10:17 pmCUN Cancun-TYS Knoxville McGhee Tyson

8h 03m1 stop Chicago O'Hare Intl

$670American Airlines

Mon, Aug 24 - Fri, Aug 28

6:03 am - 2:54 pmTYS Knoxville McGhee Tyson-CUN Cancun

9h 51m1 stop Dallas/Fort Worth

2:07 pm - 11:51 pmCUN Cancun-TYS Knoxville McGhee Tyson

8h 44m1 stop Miami

$670American Airlines

Mon, Aug 24 - Fri, Aug 28

7:00 am - 1:10 pmTYS Knoxville McGhee Tyson-CUN Cancun

7h 10m1 stop Chicago O'Hare Intl

7:51 am - 6:17 pmCUN Cancun-TYS Knoxville McGhee Tyson

9h 26m1 stop Houston George Bush Intcntl

$780United Airlines

Fri, Aug 21 - Thu, Aug 27

7:15 am - 3:40 pmTYS Knoxville McGhee Tyson-MEX Mexico City Benito Juarez

10h 25m1 stop Houston George Bush Intcntl

4:40 am - 1:20 pmMEX Mexico City Benito Juarez-TYS Knoxville McGhee Tyson

6h 40m1 stop Houston George Bush Intcntl

$855United Airlines

Mon, Aug 24 - Mon, Aug 31

7:30 am - 3:20 pmTYS Knoxville McGhee Tyson-MEX Mexico City Benito Juarez

9h 50m2 stops Atlanta Hartsfield-Jackson Guadalajara Miguel Hidal

8:15 am - 8:10 pmMEX Mexico City Benito Juarez-TYS Knoxville McGhee Tyson

9h 55m2 stops Houston George Bush Intcntl Atlanta Hartsfield-Jackson

$930Delta

Fri, Aug 21 - Tue, Aug 25

7:30 am - 3:20 pmTYS Knoxville McGhee Tyson-MEX Mexico City Benito Juarez

9h 50m2 stops Atlanta Hartsfield-Jackson Guadalajara Miguel Hidal

9:05 am - 8:10 pmMEX Mexico City Benito Juarez-TYS Knoxville McGhee Tyson

9h 05m2 stops San Antonio Atlanta Hartsfield-Jackson

$930Delta

Fri, Aug 21 - Mon, Aug 24

5:40 am - 3:37 pmTYS Knoxville McGhee Tyson-CZM Cozumel Intl

10h 57m2 stops Atlanta Hartsfield-Jackson Mexico City Benito Juarez

4:59 pm - 11:52 pmCZM Cozumel Intl-TYS Knoxville McGhee Tyson

29h 53m2 stops Mexico City Benito Juarez Atlanta Hartsfield-Jackson

$1,316Aeromexico

Fri, Aug 21 - Thu, Aug 27

4:38 pm - 3:37 pmTYS Knoxville McGhee Tyson-CZM Cozumel Intl

23h 59m2 stops Atlanta Hartsfield-Jackson Mexico City Benito Juarez

4:29 pm - 3:30 pmCZM Cozumel Intl-TYS Knoxville McGhee Tyson

22h 01m2 stops Mexico City Benito Juarez Atlanta Hartsfield-Jackson

$1,412Aeromexico

Mon, Aug 24 - Fri, Aug 28

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Delta flights from Knoxville to Mexico

Our best Delta deals on Knoxville to Mexico flight tickets

Delta

Dec 3

TYS2:40 pmKnoxville McGhee Tyson

6h 30m

1 stop

CUN9:10 pmCancun

Dec 8

CUN1:30 pmCancun

7h 58m

1 stop

TYS9:28 pmKnoxville McGhee Tyson

$593

Delta

Oct 24

TYS5:40 amKnoxville McGhee Tyson

5h 14m

1 stop

CUN9:54 amCancun

Oct 31

CUN9:24 amCancun

11h 58m

2 stops

TYS10:22 pmKnoxville McGhee Tyson

$618

Delta

Sep 16

TYS7:50 amKnoxville McGhee Tyson

9h 55m

2 stops

MEX3:45 pmMexico City Benito Juarez

Sep 23

MEX8:35 amMexico City Benito Juarez

11h 09m

2 stops

TYS9:44 pmKnoxville McGhee Tyson

$640

American Airlines flights from Knoxville to Mexico

Our best American Airlines deals on Knoxville to Mexico flight tickets

American Airlines

Sep 30

TYS7:00 amKnoxville McGhee Tyson

5h 34m

1 stop

CUN11:34 amCancun

Oct 7

CUN12:45 pmCancun

9h 14m

1 stop

TYS10:59 pmKnoxville McGhee Tyson

$520

American Airlines

Sep 14

TYS6:15 amKnoxville McGhee Tyson

8h 20m

1 stop

CUN1:35 pmCancun

Sep 18

CUN2:07 pmCancun

8h 00m

1 stop

TYS11:07 pmKnoxville McGhee Tyson

$562

American Airlines

Sep 14

TYS6:05 amKnoxville McGhee Tyson

10h 20m

1 stop

CUN3:25 pmCancun

Sep 18

CUN12:34 pmCancun

9h 16m

2 stops

TYS10:50 pmKnoxville McGhee Tyson

$567

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMexico City

TYS Knoxville McGhee Tyson - MEX Mexico City Benito Juarez

TYSMEX

Knoxville McGhee Tyson

Fri 9/11

8:20 am-7:45 pm

1 stop13h 25m

Mexico City Benito Juarez

Mon 9/14

11:05 am-8:39 pm

1 stop7h 34m

$422

KnoxvilleMexico City

TYS Knoxville McGhee Tyson - MEX Mexico City Benito Juarez

TYSMEX

Knoxville McGhee Tyson

Fri 9/11

8:00 am-10:15 pm

2 stops16h 15m

Mexico City Benito Juarez

Mon 9/14

11:05 am-8:39 pm

1 stop7h 34m

$448

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Fri 12/4

7:55 am-5:00 pm

1 stop9h 05m

Cancun

Tue 12/8

12:35 pm-8:45 pm

1 stop8h 10m

$474

Quickest round-trip

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Sat 10/24

8:10 am-1:15 pm

1 stop6h 05m

Cancun

Thu 10/29

1:00 pm-9:30 pm

1 stop7h 30m

$485

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Wed 9/30

7:00 am-11:34 am

1 stop5h 34m

Cancun

Wed 10/7

12:45 pm-10:59 pm

1 stop9h 14m

$520

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Mon 9/14

6:15 am-1:35 pm

1 stop8h 20m

Cancun

Fri 9/18

2:07 pm-11:07 pm

1 stop8h 00m

$562

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Wed 9/30

5:45 am-11:05 am

1 stop6h 20m

Cancun

Wed 10/7

12:11 pm-8:49 pm

1 stop7h 38m

$568

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Mon 11/16

7:10 am-12:32 am

2 stops17h 22m

Cancun

Wed 11/25

9:24 am-10:22 pm

2 stops12h 58m

$568

KnoxvilleCancún

TYS Knoxville McGhee Tyson - CUN Cancun

TYSCUN

Knoxville McGhee Tyson

Wed 10/28

5:40 am-2:25 pm

1 stop9h 45m

Cancun

Thu 11/5

8:00 am-1:31 pm

1 stop5h 31m

$568

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Tue 9/29

7:25 pm-2:42 pm

2 stops20h 17m

Cozumel Intl

Tue 10/6

3:52 pm-9:45 am

2 stops16h 53m

$585

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in April, then January is your next best option. Flight prices from Knoxville to Mexico during January average around $644.

Can stopping save me money on Knoxville to Mexico flights?

You could potentially save up to 3% on your flight if you consider stops on a Knoxville to Mexico flight.

Cheap Knoxville to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Mexico

Best Price Found	$179
Fastest flight time	5h 03m
Direct flights	None

The best one-way flight to Mexico from Knoxville in the past 72 hours is $179. The best round-trip flight deal from Knoxville to Mexico found on momondo in the last 72 hours is $422.

The fastest flight from Knoxville to Mexico takes 5h 03m

There are no direct flights from Knoxville to Mexico. There are no popular flight routes from Knoxville to Mexico.

Search flight deals

Frequently asked questions about flying from Knoxville to Mexico

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Mexico?
Prices for flights from Knoxville McGhee Tyson Airport to Mexico were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Mexico?
As of August 2026, there are 5 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Mexico.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Mexico?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Mexico.
What documentation or ID do you need to fly to Mexico?
The travel and health documents required for your trip to Mexico can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mexico. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Mexico

Compare and see reviews for airlines that fly from Knoxville to Mexico with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $318	Free Cancellation	Rating 7.8 8,498 reviews	Search Delta flights
United Airlines	PriceFrom $473	Free Cancellation	Rating 7.4 10,104 reviews	Search United Airlines flights
American Airlines	PriceFrom $505	Free Cancellation	Rating 7.1 11,960 reviews	Search American Airlines flights
Aeromexico	PriceFrom $511	Free Cancellation	Rating 7.4 1,472 reviews	Search Aeromexico flights
Southwest	PriceFrom $531	Free Cancellation	Rating 8.0 4,219 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Mexico?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Mexico. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Mexico with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Mexico from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Mexico?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Mexico.

I’m not ready to book a flight from Knoxville to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.