What is the cheapest airline that flies from Knoxville McGhee Tyson to Mexico?

Aeromexico, Delta, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Mexico

What airlines fly to Mexico?

American Airlines, Delta and Aeromexico are the top three most popular airlines that fly to Mexico from Knoxville according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Mexico. Keep in mind that there are 4 different airlines that fly to Mexico on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Mexico?

Prices for flights from Knoxville McGhee Tyson Airport to Mexico were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Mexico?

As of December 2025, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Mexico.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Mexico?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Mexico.

What documentation or ID do you need to fly to Mexico?

The travel and health documents required for your trip to Mexico can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mexico. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$243 Cheap Flights from Knoxville to Mexico in 2025/26

1 adult

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Find the cheapest flights from Knoxville to Mexico

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:30 pm - 9:13 am

TYS

CUN

15h 43m1 stop

12:55 pm - 10:10 am

CUN

TYS

21h 15m2 stops

$329Multiple Airlines

Sat, Jan 17 - Thu, Jan 22

5:30 pm - 9:13 am

TYS

CUN

15h 43m1 stop

10:13 am - 10:10 am

CUN

TYS

23h 57m1 stop

$337Multiple Airlines

Sat, Jan 17 - Thu, Jan 22

5:30 am - 1:05 pm

TYS

CZM

9h 35m1 stop

2:20 pm - 11:51 pm

CZM

TYS

7h 31m1 stop

$488Delta

Mon, Mar 23 - Tue, Mar 31

6:00 am - 7:36 pm

TYS

MEX

14h 36m1 stop

6:45 am - 5:06 pm

MEX

TYS

9h 21m1 stop

$501American Airlines

Fri, Jan 30 - Fri, Feb 6

5:30 am - 3:18 pm

TYS

CZM

11h 48m2 stops

2:20 pm - 11:51 pm

CZM

TYS

7h 31m1 stop

$506Delta

Sun, Mar 22 - Wed, Apr 1

5:30 am - 1:05 pm

TYS

CZM

9h 35m1 stop

2:20 pm - 11:51 pm

CZM

TYS

7h 31m1 stop

$513Aeromexico

Fri, Mar 27 - Wed, Apr 1

5:40 am - 1:50 pm

TYS

CZM

9h 10m1 stop

3:05 pm - 11:45 pm

CZM

TYS

7h 40m1 stop

$530Aeromexico

Mon, Jan 19 - Mon, Jan 26

7:39 pm - 8:55 am

TYS

MEX

15h 16m1 stop

10:20 am - 9:05 pm

MEX

TYS

8h 45m1 stop

$550American Airlines

Mon, Mar 16 - Tue, Mar 24

9:10 am - 2:32 pm

TYS

SJD

7h 22m1 stop

2:11 pm - 10:19 am

SJD

TYS

18h 08m2 stops

$598United Airlines

Sat, Feb 14 - Tue, Feb 17

4:55 pm - 10:47 am

TYS

PVR

18h 52m1 stop

3:40 pm - 11:44 pm

PVR

TYS

7h 04m1 stop

$604United Airlines

Sat, Jan 17 - Sat, Jan 24

American Airlines flights from Knoxville to Mexico

Our best American Airlines deals on Knoxville to Mexico flight tickets

American Airlines

Jan 30

TYS6:00 amKnoxville McGhee Tyson

14h 36m

1 stop

MEX7:36 pmMexico City Benito Juarez

Feb 6

MEX6:45 amMexico City Benito Juarez

9h 21m

1 stop

TYS5:06 pmKnoxville McGhee Tyson

$501

Find similar

American Airlines

Mar 23

TYS6:21 pmKnoxville McGhee Tyson

20h 07m

1 stop

GDL12:28 pmGuadalajara Miguel Hidal

Apr 9

GDL6:00 amGuadalajara Miguel Hidal

9h 26m

1 stop

TYS5:26 pmKnoxville McGhee Tyson

$528

Find similar

American Airlines

Mar 16

TYS7:39 pmKnoxville McGhee Tyson

15h 16m

1 stop

MEX8:55 amMexico City Benito Juarez

Mar 24

MEX10:20 amMexico City Benito Juarez

8h 45m

1 stop

TYS9:05 pmKnoxville McGhee Tyson

$550

Find similar

WestJet flights from Knoxville to Mexico

Our best WestJet deals on Knoxville to Mexico flight tickets

WestJet

Feb 18

TYS5:30 amKnoxville McGhee Tyson

20h 30m

2 stops

MEX1:00 amMexico City Benito Juarez

Feb 20

MEX12:30 amMexico City Benito Juarez

43h 15m

2 stops

TYS8:45 pmKnoxville McGhee Tyson

$1,259

Find similar

WestJet

Dec 19

TYS10:23 amKnoxville McGhee Tyson

50h 52m

2 stops

PVR12:15 pmPuerto Vallarta Ordaz

Dec 31

PVR1:00 pmPuerto Vallarta Ordaz

29h 27m

2 stops

TYS7:27 pmKnoxville McGhee Tyson

$2,690

Find similar

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sat 1/17

5:30 pm-9:13 am

1 stop15h 43m

Cancun

Thu 1/22

12:55 pm-10:10 am

2 stops21h 15m

$329

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sat 1/17

5:30 pm-9:13 am

1 stop15h 43m

Cancun

Thu 1/22

10:13 am-10:10 am

1 stop23h 57m

$337

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Mon 3/23

5:30 am-1:05 pm

1 stop9h 35m

Cozumel

Tue 3/31

2:20 pm-11:51 pm

1 stop7h 31m

$488

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Fri 1/30

6:00 am-7:36 pm

1 stop14h 36m

Mexico City Benito Juarez

Fri 2/6

6:45 am-5:06 pm

1 stop9h 21m

$501

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Sun 3/22

5:30 am-3:18 pm

2 stops11h 48m

Cozumel

Wed 4/1

2:20 pm-11:51 pm

1 stop7h 31m

$506

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Fri 3/27

5:30 am-1:05 pm

1 stop9h 35m

Cozumel

Wed 4/1

2:20 pm-11:51 pm

1 stop7h 31m

$513

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Mon 1/19

5:40 am-1:50 pm

1 stop9h 10m

Cozumel

Mon 1/26

3:05 pm-11:45 pm

1 stop7h 40m

$530

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 3/16

7:39 pm-8:55 am

1 stop15h 16m

Mexico City Benito Juarez

Tue 3/24

10:20 am-9:05 pm

1 stop8h 45m

$550

KnoxvilleSan José del Cabo

TYS - SJD

TYSSJD

Knoxville McGhee Tyson

Sat 2/14

9:10 am-2:32 pm

1 stop7h 22m

San José del Cabo Los Cabos

Tue 2/17

2:11 pm-10:19 am

2 stops18h 08m

$598

KnoxvillePuerto Vallarta

TYS - PVR

TYSPVR

Knoxville McGhee Tyson

Sat 1/17

4:55 pm-10:47 am

1 stop18h 52m

Puerto Vallarta Ordaz

Sat 1/24

3:40 pm-11:44 pm

1 stop7h 04m

$604

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in August, then December is your next best option. Flight prices from Knoxville to Mexico during December average around $540.

What is the cheapest day to depart on your flight to Mexico?

The cheapest day to depart on your flight to Mexico is on a Tuesday when prices can be found for as low as $513. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $644. These prices are subject to change though, so be sure to set up a Price Alert for flights to Mexico.

What is the cheapest time of day to depart on your flight to Mexico?

Our data shows that the cheapest Knoxville to Mexico flights are usually those with departure times in the afternoon. Our users have found flights to Mexico in the afternoon for as low as $547. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $616 on average. Flights to Mexico from Knoxville in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to Mexico?

You are more likely to see cheaper flights to Mexico from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico for around $585 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico from Knoxville for as low as $517 on momondo.

Can stopping save me money on Knoxville to Mexico flights?

You could potentially save up to 28% on your flight if you consider stops on a Knoxville to Mexico flight.

Cheap Knoxville to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Mexico

Fastest flight time	5h 25m
Direct flights	None

The fastest flight from Knoxville to Mexico takes 5h 25m

There are no direct flights from Knoxville to Mexico. There are no popular flight routes from Knoxville to Mexico.

Search flight deals

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Mexico?
Prices for flights from Knoxville McGhee Tyson Airport to Mexico were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Mexico?
As of December 2025, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Mexico.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Mexico?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Mexico.
What documentation or ID do you need to fly to Mexico?
The travel and health documents required for your trip to Mexico can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mexico. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Mexico

Compare and see reviews for airlines that fly from Knoxville to Mexico with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $318	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights
American Airlines	PriceFrom $455	Free Cancellation	Rating 7.2 11,055 reviews	Search American Airlines flights
United Airlines	PriceFrom $477	Free Cancellation	Rating 7.4 9,093 reviews	Search United Airlines flights
Aeromexico	PriceFrom $479	Free Cancellation	Rating 7.4 1,629 reviews	Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Mexico?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Mexico. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Mexico with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Mexico from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Mexico?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Mexico.

I’m not ready to book a flight from Knoxville to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.