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Cheap flights from Knoxville to Mexico from $180

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Mexico departing on 11/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Mexico

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:56 pm - 11:36 amTYS-CUN
17h 40m1 stop
Multiple Airlines Logo
3:38 pm - 4:15 pmCUN-TYS
24h 37m1 stop
$381Multiple Airlines
Find Deal
Fri, Dec 12 - Tue, Dec 23
Multiple Airlines Logo
4:27 pm - 1:35 pmTYS-CUN
21h 08m1 stop
Multiple Airlines Logo
2:36 pm - 8:33 amCUN-TYS
17h 57m1 stop
$398Multiple Airlines
Find Deal
Thu, Nov 27 - Thu, Dec 4
Delta Logo
7:30 am - 2:00 pmTYS-CUN
6h 30m1 stop
Delta Logo
12:25 pm - 8:47 pmCUN-TYS
8h 22m1 stop
$487Delta
Find Deal
Tue, Jan 13 - Tue, Feb 3
American Airlines Logo
7:06 pm - 10:45 amTYS-CUN
15h 39m1 stop
American Airlines Logo
1:11 pm - 11:59 pmCUN-TYS
10h 48m1 stop
$490American Airlines
Find Deal
Sun, Feb 15 - Fri, Feb 20
Delta Logo
7:59 pm - 1:30 pmTYS-CUN
17h 31m2 stops
Delta Logo
8:00 am - 6:14 pmCUN-TYS
10h 14m1 stop
$491Delta
Find Deal
Mon, Dec 15 - Fri, Dec 26
Aeromexico Logo
10:05 am - 10:25 pmTYS-GDL
14h 20m2 stops
Aeromexico Logo
1:18 pm - 11:44 pmGDL-TYS
8h 26m1 stop
$511Aeromexico
Find Deal
Tue, Mar 10 - Wed, Mar 11
American Airlines Logo
7:54 am - 9:28 pmTYS-GDL
14h 34m2 stops
American Airlines Logo
4:44 pm - 9:45 amGDL-TYS
16h 01m2 stops
$516American Airlines
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Tue, Jan 6 - Tue, Jan 13
United Airlines Logo
6:45 am - 1:23 pmTYS-CZM
7h 38m1 stop
United Airlines Logo
2:25 pm - 11:44 pmCZM-TYS
8h 19m1 stop
$524United Airlines
Find Deal
Fri, Jan 9 - Fri, Jan 16
United Airlines Logo
7:20 pm - 12:58 pmTYS-CZM
18h 38m2 stops
United Airlines Logo
2:25 pm - 10:32 amCZM-TYS
19h 07m2 stops
$528United Airlines
Find Deal
Fri, Jan 9 - Fri, Jan 16
Aeromexico Logo
5:30 am - 7:50 pmTYS-MEX
16h 20m1 stop
Aeromexico Logo
7:05 am - 11:44 pmMEX-TYS
14h 39m2 stops
$554Aeromexico
Find Deal
Tue, Mar 10 - Wed, Mar 11

Aeromexico flights from Knoxville to Mexico

Our best Aeromexico deals on Knoxville to Mexico flight tickets
Aeromexico
Mar 10
TYS10:05 amKnoxville McGhee Tyson
14h 20m
2 stops
GDL10:25 pmGuadalajara Miguel Hidal
Mar 11
GDL1:18 pmGuadalajara Miguel Hidal
8h 26m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
$511
Find similar
Aeromexico
Mar 10
TYS5:30 amKnoxville McGhee Tyson
16h 20m
1 stop
MEX7:50 pmMexico City Benito Juarez
Mar 11
MEX7:05 amMexico City Benito Juarez
14h 39m
2 stops
TYS11:44 pmKnoxville McGhee Tyson
$554
Find similar
Aeromexico
Mar 27
TYS8:47 amKnoxville McGhee Tyson
6h 18m
1 stop
CZM1:05 pmCozumel
Apr 1
CZM2:20 pmCozumel
7h 24m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
$558
Find similar

United Airlines flights from Knoxville to Mexico

Our best United Airlines deals on Knoxville to Mexico flight tickets
United Airlines
Jan 9
TYS6:45 amKnoxville McGhee Tyson
7h 38m
1 stop
CZM1:23 pmCozumel
Jan 16
CZM2:25 pmCozumel
8h 19m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
$524
Find similar
United Airlines
Jan 9
TYS7:20 pmKnoxville McGhee Tyson
18h 38m
2 stops
CZM12:58 pmCozumel
Jan 16
CZM2:25 pmCozumel
19h 07m
2 stops
TYS10:32 amKnoxville McGhee Tyson
$528
Find similar
United Airlines
Jan 10
TYS6:45 amKnoxville McGhee Tyson
8h 34m
1 stop
CZM2:19 pmCozumel
Jan 17
CZM4:42 pmCozumel
16h 50m
2 stops
TYS10:32 amKnoxville McGhee Tyson
$553
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Fri 12/12

5:56 pm-11:36 am

1 stop17h 40m

Cancun

Tue 12/23

3:38 pm-4:15 pm

1 stop24h 37m

$381

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Thu 11/27

4:27 pm-1:35 pm

1 stop21h 08m

Cancun

Thu 12/4

2:36 pm-8:33 am

1 stop17h 57m

$398

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Tue 1/13

7:30 am-2:00 pm

1 stop6h 30m

Cancun

Tue 2/3

12:25 pm-8:47 pm

1 stop8h 22m

$487

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sun 2/15

7:06 pm-10:45 am

1 stop15h 39m

Cancun

Fri 2/20

1:11 pm-11:59 pm

1 stop10h 48m

$490

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Mon 12/15

7:59 pm-1:30 pm

2 stops17h 31m

Cancun

Fri 12/26

8:00 am-6:14 pm

1 stop10h 14m

$491

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Tue 3/10

10:05 am-10:25 pm

2 stops14h 20m

Guadalajara Miguel Hidal

Wed 3/11

1:18 pm-11:44 pm

1 stop8h 26m

$511

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Tue 1/6

7:54 am-9:28 pm

2 stops14h 34m

Guadalajara Miguel Hidal

Tue 1/13

4:44 pm-9:45 am

2 stops16h 01m

$516

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Fri 1/9

6:45 am-1:23 pm

1 stop7h 38m

Cozumel

Fri 1/16

2:25 pm-11:44 pm

1 stop8h 19m

$524

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Fri 1/9

7:20 pm-12:58 pm

2 stops18h 38m

Cozumel

Fri 1/16

2:25 pm-10:32 am

2 stops19h 07m

$528

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 3/10

5:30 am-7:50 pm

1 stop16h 20m

Mexico City Benito Juarez

Wed 3/11

7:05 am-11:44 pm

2 stops14h 39m

$554

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico from

How to get the cheapest flight ticket from Knoxville to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in July, then April is your next best option. Flight prices from Knoxville to Mexico during April average around $554.

What is the cheapest day to depart on your flight to Mexico?

The cheapest day to depart on your flight to Mexico is on a Tuesday when prices can be found for as low as $513. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $644. These prices are subject to change though, so be sure to set up a Price Alert for flights to Mexico.

What is the cheapest time of day to depart on your flight to Mexico?

Our data shows that the cheapest Knoxville to Mexico flights are usually those with departure times in the afternoon. Our users have found flights to Mexico in the afternoon for as low as $547. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $616 on average. Flights to Mexico from Knoxville in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to Mexico?

You are more likely to see cheaper flights to Mexico from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico for around $600 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico from Knoxville for as low as $538 on momondo.

Can stopping save me money on Knoxville to Mexico flights?

You could potentially save up to 31% on your flight if you consider stops on a Knoxville to Mexico flight.

Cheap Knoxville to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Mexico

Direct flights

None
There are no direct flights from Knoxville to Mexico. There are no popular flight routes from Knoxville to Mexico.
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  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Mexico?

    Prices for flights from Knoxville McGhee Tyson Airport to Mexico were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Mexico?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Mexico?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Mexico.

  • What documentation or ID do you need to fly to Mexico?

    The travel and health documents required for your trip to Mexico can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mexico. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Mexico

Compare and see reviews for airlines that fly from Knoxville to Mexico with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $318Free CancellationRating
7.9
8,001 reviews
Search Delta flights
American AirlinesPriceFrom $455Free CancellationRating
7.2
11,036 reviews
Search American Airlines flights
United AirlinesPriceFrom $477Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights
AeromexicoPriceFrom $479Free CancellationRating
7.4
1,673 reviews
Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Mexico?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Mexico. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Mexico with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Mexico from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Mexico?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Mexico.

I’m not ready to book a flight from Knoxville to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Mexico trip

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Find better results for your trip to Mexico

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