What is the cheapest airline that flies from Knoxville McGhee Tyson to Manchester?

United Airlines and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Manchester

What airlines fly to Manchester, New Hampshire?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Manchester, New Hampshire from Knoxville according to our data. Allegiant Air is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Manchester, New Hampshire. Keep in mind that there are 5 different airlines that fly to Manchester, New Hampshire on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

As of September 2026, there is 1 operator available to choose from for flights from Knoxville McGhee Tyson Airport to Manchester Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

What documentation or ID do you need to fly to Manchester Airport?

The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$159 Cheap Flights from Knoxville to Manchester, New Hampshire in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Boston

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One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:05 pm - 11:36 pmTYS Knoxville McGhee Tyson-MHT Manchester

5h 31m1 stop Philadelphia

6:00 am - 10:25 amMHT Manchester-TYS Knoxville McGhee Tyson

4h 25m1 stop Washington, D.C. Reagan-National

$317American Airlines

Thu, Oct 15 - Tue, Oct 20

6:05 pm - 12:23 amTYS Knoxville McGhee Tyson-MHT Manchester

6h 18m1 stop Washington, D.C. Reagan-National

6:00 am - 10:33 amMHT Manchester-TYS Knoxville McGhee Tyson

4h 33m1 stop Philadelphia

$317American Airlines

Thu, Oct 15 - Tue, Oct 20

6:05 pm - 11:36 pmTYS Knoxville McGhee Tyson-MHT Manchester

5h 31m1 stop Philadelphia

7:15 pm - 11:55 pmMHT Manchester-TYS Knoxville McGhee Tyson

4h 40m1 stop Charlotte Douglas

$317American Airlines

Mon, Oct 19 - Mon, Oct 26

6:05 pm - 11:36 pmTYS Knoxville McGhee Tyson-MHT Manchester

5h 31m1 stop Philadelphia

6:00 am - 10:25 amMHT Manchester-TYS Knoxville McGhee Tyson

4h 25m1 stop Washington, D.C. Reagan-National

$398American Airlines

Fri, Oct 16 - Sun, Oct 18

6:05 pm - 12:23 amTYS Knoxville McGhee Tyson-MHT Manchester

6h 18m1 stop Washington, D.C. Reagan-National

7:15 pm - 11:55 pmMHT Manchester-TYS Knoxville McGhee Tyson

4h 40m1 stop Charlotte Douglas

$412American Airlines

Wed, Oct 7 - Mon, Oct 26

6:05 pm - 11:36 pmTYS Knoxville McGhee Tyson-MHT Manchester

5h 31m1 stop Philadelphia

6:00 am - 10:25 amMHT Manchester-TYS Knoxville McGhee Tyson

4h 25m1 stop Washington, D.C. Reagan-National

$412American Airlines

Sat, Oct 10 - Sat, Oct 17

6:20 am - 11:09 amTYS Knoxville McGhee Tyson-MHT Manchester

4h 49m1 stop Charlotte Douglas

6:00 am - 10:25 amMHT Manchester-TYS Knoxville McGhee Tyson

4h 25m1 stop Washington, D.C. Reagan-National

$412American Airlines

Tue, Oct 6 - Tue, Oct 20

7:35 pm - 11:59 pmTYS Knoxville McGhee Tyson-MHT Manchester

4h 24m1 stop Washington, D.C. Dulles Intl

9:25 am - 2:48 pmMHT Manchester-TYS Knoxville McGhee Tyson

5h 23m1 stop Washington, D.C. Dulles Intl

$417United Airlines

Wed, Oct 28 - Sat, Oct 31

4:30 pm - 11:59 pmTYS Knoxville McGhee Tyson-MHT Manchester

7h 29m2 stops Newark Washington, D.C. Dulles Intl

9:25 am - 2:48 pmMHT Manchester-TYS Knoxville McGhee Tyson

5h 23m1 stop Washington, D.C. Dulles Intl

$422United Airlines

Wed, Oct 28 - Sat, Oct 31

7:35 pm - 11:59 pmTYS Knoxville McGhee Tyson-MHT Manchester

4h 24m1 stop Washington, D.C. Dulles Intl

9:25 am - 8:54 pmMHT Manchester-TYS Knoxville McGhee Tyson

11h 29m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$438United Airlines

Wed, Oct 28 - Sat, Oct 31

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United Airlines flights from Knoxville to Manchester, New Hampshire

Our best United Airlines deals on Knoxville to Manchester, New Hampshire flight tickets

United Airlines

Oct 28

TYS7:35 pmKnoxville McGhee Tyson

4h 24m

1 stop

MHT11:59 pmManchester

Oct 31

MHT9:25 amManchester

5h 23m

1 stop

TYS2:48 pmKnoxville McGhee Tyson

$417

United Airlines

Oct 28

TYS4:30 pmKnoxville McGhee Tyson

7h 29m

2 stops

MHT11:59 pmManchester

Oct 31

MHT9:25 amManchester

5h 23m

1 stop

TYS2:48 pmKnoxville McGhee Tyson

$422

United Airlines

Oct 28

TYS7:35 pmKnoxville McGhee Tyson

4h 24m

1 stop

MHT11:59 pmManchester

Oct 31

MHT9:25 amManchester

11h 29m

2 stops

TYS8:54 pmKnoxville McGhee Tyson

$438

American Airlines flights from Knoxville to Manchester, New Hampshire

Our best American Airlines deals on Knoxville to Manchester, New Hampshire flight tickets

American Airlines

Oct 15

TYS6:05 pmKnoxville McGhee Tyson

6h 18m

1 stop

MHT12:23 amManchester

Oct 20

MHT6:00 amManchester

4h 33m

1 stop

TYS10:33 amKnoxville McGhee Tyson

$317

American Airlines

Oct 16

TYS6:05 pmKnoxville McGhee Tyson

5h 31m

1 stop

MHT11:36 pmManchester

Oct 18

MHT6:00 amManchester

4h 25m

1 stop

TYS10:25 amKnoxville McGhee Tyson

$398

American Airlines

Oct 6

TYS6:20 amKnoxville McGhee Tyson

4h 49m

1 stop

MHT11:09 amManchester

Oct 20

MHT6:00 amManchester

4h 25m

1 stop

TYS10:25 amKnoxville McGhee Tyson

$412

momondo Fare Finder

Use the filters below to find and compare flights from Knoxville to Manchester, New Hampshire that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Thu 10/15

6:05 pm-11:36 pm

1 stop5h 31m

Manchester

Tue 10/20

6:00 am-10:25 am

1 stop4h 25m

$317

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Thu 10/15

6:05 pm-12:23 am

1 stop6h 18m

Manchester

Tue 10/20

6:00 am-10:33 am

1 stop4h 33m

$317

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Mon 10/19

6:05 pm-11:36 pm

1 stop5h 31m

Manchester

Mon 10/26

7:15 pm-11:55 pm

1 stop4h 40m

$317

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Fri 10/16

6:05 pm-11:36 pm

1 stop5h 31m

Manchester

Sun 10/18

6:00 am-10:25 am

1 stop4h 25m

$398

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Wed 10/7

6:05 pm-12:23 am

1 stop6h 18m

Manchester

Mon 10/26

7:15 pm-11:55 pm

1 stop4h 40m

$412

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Sat 10/10

6:05 pm-11:36 pm

1 stop5h 31m

Manchester

Sat 10/17

6:00 am-10:25 am

1 stop4h 25m

$412

Quickest round-trip

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Tue 10/6

6:20 am-11:09 am

1 stop4h 49m

Manchester

Tue 10/20

6:00 am-10:25 am

1 stop4h 25m

$412

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Wed 10/28

7:35 pm-11:59 pm

1 stop4h 24m

Manchester

Sat 10/31

9:25 am-2:48 pm

1 stop5h 23m

$417

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Wed 10/28

4:30 pm-11:59 pm

2 stops7h 29m

Manchester

Sat 10/31

9:25 am-2:48 pm

1 stop5h 23m

$422

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MHT Manchester

TYSMHT

Knoxville McGhee Tyson

Wed 10/28

7:35 pm-11:59 pm

1 stop4h 24m

Manchester

Sat 10/31

9:25 am-8:54 pm

2 stops11h 29m

$438

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Manchester, New Hampshire

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Knoxville and Manchester, New Hampshire?

Prices are currently low for flights on this route.

Typical prices usually range from $368 to $426.
The lowest price recently found on this route was $317.

What is the cheapest month to fly to Manchester, New Hampshire?

If you aren’t able to travel during the month of February, then book flights to Manchester, New Hampshire from Knoxville during June instead. Flights to Manchester, New Hampshire in June, while not as cheap as those in February, still average around $343.

When to book flights from Knoxville to Manchester, New Hampshire

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester, New Hampshire according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Manchester, New Hampshire (TYS to MHT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester, New Hampshire

Best Price Found	$159
Fastest flight time	4h 24m
Direct flights	None

The best one-way flight to Manchester, New Hampshire from Knoxville in the past 72 hours is $159. The best round-trip flight deal from Knoxville to Manchester, New Hampshire found on momondo in the last 72 hours is $317.

The fastest flight from Knoxville to Manchester, New Hampshire takes 4h 24m

There are no direct flights from Knoxville to Manchester, New Hampshire. There are no popular flight routes from Knoxville to Manchester, New Hampshire.

Search flight deals

Frequently asked questions about flying from Knoxville to Manchester, New Hampshire

How far is Knoxville McGhee Tyson to Manchester by plane?
Knoxville McGhee Tyson and Manchester are 821.5 mi apart from one another. By plane, this route typically takes 4h 24m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Manchester Airport?
As of September 2026, there is 1 operator available to choose from for flights from Knoxville McGhee Tyson Airport to Manchester Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.
What documentation or ID do you need to fly to Manchester Airport?
The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Manchester, New Hampshire?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Manchester, New Hampshire is American Airlines (100% of total bookings).

Best airlines flying from Knoxville to Manchester, New Hampshire

Compare and see reviews for airlines that fly from Knoxville to Manchester, New Hampshire with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $310	Free Cancellation	Rating 7.0 12,076 reviews		Search American Airlines flights

Keene

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

Finding the right flight to Manchester from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Manchester quick and easy, saving you time and money.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo helps you find the best flight between Knoxville and Manchester by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Cheap flights from Knoxville to Boston from $159

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Boston departing on 10/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Knoxville to Manchester, New Hampshire

Our best United Airlines deals on Knoxville to Manchester, New Hampshire flight tickets

American Airlines flights from Knoxville to Manchester, New Hampshire

Our best American Airlines deals on Knoxville to Manchester, New Hampshire flight tickets

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Use the filters below to find and compare flights from Knoxville to Manchester, New Hampshire that are best for you.

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How to get the cheapest flight ticket from Knoxville to Manchester, New Hampshire

What is the typical price of a round-trip flight between Knoxville and Manchester, New Hampshire?

What is the cheapest month to fly to Manchester, New Hampshire?

What is the cheapest airline that flies from Knoxville McGhee Tyson to Manchester?

What airlines fly to Manchester, New Hampshire?

When to book flights from Knoxville to Manchester, New Hampshire

Cheap Knoxville to Manchester, New Hampshire (TYS to MHT) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Knoxville to Manchester, New Hampshire

Best airlines flying from Knoxville to Manchester, New Hampshire

Compare and see reviews for airlines that fly from Knoxville to Manchester, New Hampshire with momondo

Traveling to a place near Boston?

Why use momondo?

An easier way to manage your Manchester, New Hampshire trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

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List of cabin classes available on flights landing in Boston. Availability may vary depending on flight origin and airline.

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