Cheap flights from Knoxville to Colorado from $52

The month of August is, on average, the cheapest month to fly to Colorado from Knoxville, with most prices found around $256. The month of September is another great option to travel to Colorado, with average flight prices from Knoxville averaging around $265.

The cheapest day to depart from Knoxville to Colorado is on a Sunday when prices can be found for as low as $311. On the other hand, Wednesday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $458.

The cheapest time of day to fly to Colorado is in the evening when flights can be purchased for as low as $252. In the morning is when there is more demand to fly to Colorado, so prices are often more expensive at around $451 per ticket.

Fly from Knoxville McGhee Tyson to Denver Intl for the best Knoxville McGhee Tyson - Colorado flight prices

You are more likely to see cheaper flights to Colorado from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Colorado for around $304 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Colorado from Knoxville for as low as $242 on momondo.

There are 4 cabin classes available to choose from on Knoxville to Colorado flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

American Airlines, Delta, and Southwest are the most popular carriers operating from Knoxville McGhee Tyson to Colorado

United Airlines, American Airlines and Allegiant Air are the top three most popular airlines that fly to Colorado from Knoxville according to our data. United Airlines is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Colorado. Keep in mind that there are 6 different airlines that fly to Colorado on a routine basis, so you have a few additional options to choose from.

As of September 2026, there are 1 flights per day flying from Knoxville to Colorado. The most common time of day flights depart is 4:00PM, with 57% of flights taking off in the afternoon.

As of September 2026, 11 flights take off from Knoxville and land in Colorado each week. The most common flight departure day for this route is Mon, with 27% of weekly flights taking off on this day.