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Cheap flights from Knoxville to Cleveland from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Cleveland departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Knoxville to Cleveland

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
4:28 pm - 12:57 am
TYS
-
CLE
8h 29m
1 stop
Frontier Logo
5:21 pm - 3:33 pm
CLE
-
TYS
22h 12m
1 stop
$161Frontier
Thu, Apr 16 - Sat, Apr 25
Multiple Airlines Logo
4:31 pm - 7:39 am
TYS
-
CLE
15h 08m
1 stop
Multiple Airlines Logo
6:32 pm - 1:09 pm
CLE
-
TYS
18h 37m
1 stop
$255Multiple Airlines
Thu, Apr 30 - Fri, May 1
Multiple Airlines Logo
4:25 pm - 10:46 am
TYS
-
CLE
18h 21m
2 stops
Multiple Airlines Logo
7:38 pm - 8:42 pm
CLE
-
TYS
25h 04m
1 stop
$262Multiple Airlines
Wed, Apr 8 - Wed, Apr 15
Multiple Airlines Logo
3:00 pm - 11:28 pm
TYS
-
CLE
8h 28m
1 stop
Multiple Airlines Logo
6:45 pm - 2:10 pm
CLE
-
TYS
19h 25m
1 stop
$263Multiple Airlines
Tue, Mar 24 - Mon, Mar 30
Multiple Airlines Logo
11:26 am - 7:39 am
TYS
-
CLE
20h 13m
1 stop
Multiple Airlines Logo
6:32 pm - 1:09 pm
CLE
-
TYS
18h 37m
1 stop
$273Multiple Airlines
Wed, Apr 29 - Fri, May 1
United Airlines Logo
7:00 am - 1:19 pm
TYS
-
CLE
6h 19m
1 stop
United Airlines Logo
6:00 pm - 11:08 pm
CLE
-
TYS
5h 08m
1 stop
$279United Airlines
Wed, Apr 8 - Wed, Apr 8
Multiple Airlines Logo
7:00 am - 2:27 pm
TYS
-
CLE
7h 27m
1 stop
Multiple Airlines Logo
6:45 pm - 2:10 pm
CLE
-
TYS
19h 25m
1 stop
$281Multiple Airlines
Thu, Mar 26 - Mon, Mar 30
Southwest Logo
12:50 pm - 10:15 pm
TYS
-
CLE
9h 25m
2 stops
Southwest Logo
6:40 am - 12:00 pm
CLE
-
TYS
5h 20m
1 stop
$284Southwest
Wed, Apr 8 - Wed, Apr 15
Southwest Logo
7:00 am - 12:55 pm
TYS
-
CLE
5h 55m
1 stop
Southwest Logo
3:35 pm - 9:20 pm
CLE
-
TYS
5h 45m
1 stop
$287Southwest
Sat, Jul 4 - Sat, Jul 11
Southwest Logo
7:05 am - 5:25 pm
TYS
-
CLE
10h 20m
2 stops
Southwest Logo
10:30 am - 7:40 pm
CLE
-
TYS
9h 10m
2 stops
$289Southwest
Wed, Apr 8 - Wed, Apr 15

Southwest flights from Knoxville to Cleveland

Our best Southwest deals on Knoxville to Cleveland flight tickets
Southwest
Apr 8
TYS12:50 pmKnoxville McGhee Tyson
9h 25m
2 stops
CLE10:15 pmCleveland Hopkins Intl
Apr 15
CLE6:40 amCleveland Hopkins Intl
5h 20m
1 stop
TYS12:00 pmKnoxville McGhee Tyson
$284
Southwest
Jul 4
TYS7:00 amKnoxville McGhee Tyson
5h 55m
1 stop
CLE12:55 pmCleveland Hopkins Intl
Jul 11
CLE3:35 pmCleveland Hopkins Intl
5h 45m
1 stop
TYS9:20 pmKnoxville McGhee Tyson
$287
Southwest
Apr 8
TYS7:05 amKnoxville McGhee Tyson
10h 20m
2 stops
CLE5:25 pmCleveland Hopkins Intl
Apr 15
CLE10:30 amCleveland Hopkins Intl
9h 10m
2 stops
TYS7:40 pmKnoxville McGhee Tyson
$289

United Airlines flights from Knoxville to Cleveland

Our best United Airlines deals on Knoxville to Cleveland flight tickets
United Airlines
Apr 8
TYS7:00 amKnoxville McGhee Tyson
6h 19m
1 stop
CLE1:19 pmCleveland Hopkins Intl
Apr 8
CLE6:00 pmCleveland Hopkins Intl
5h 08m
1 stop
TYS11:08 pmKnoxville McGhee Tyson
$279
United Airlines
May 22
TYS5:45 amKnoxville McGhee Tyson
3h 56m
1 stop
CLE9:41 amCleveland Hopkins Intl
May 23
CLE6:00 pmCleveland Hopkins Intl
6h 30m
1 stop
TYS12:30 amKnoxville McGhee Tyson
$318
United Airlines
Apr 7
TYS7:20 pmKnoxville McGhee Tyson
4h 39m
1 stop
CLE11:59 pmCleveland Hopkins Intl
Apr 8
CLE6:00 pmCleveland Hopkins Intl
5h 08m
1 stop
TYS11:08 pmKnoxville McGhee Tyson
$323

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Knoxville to Cleveland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Thu 4/16

4:28 pm-12:57 am

1 stop8h 29m

Cleveland Hopkins Intl

Sat 4/25

5:21 pm-3:33 pm

1 stop22h 12m

$161

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Thu 4/30

4:31 pm-7:39 am

1 stop15h 08m

Cleveland Hopkins Intl

Fri 5/1

6:32 pm-1:09 pm

1 stop18h 37m

$255

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Wed 4/8

4:25 pm-10:46 am

2 stops18h 21m

Cleveland Hopkins Intl

Wed 4/15

7:38 pm-8:42 pm

1 stop25h 04m

$262

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Tue 3/24

3:00 pm-11:28 pm

1 stop8h 28m

Cleveland Hopkins Intl

Mon 3/30

6:45 pm-2:10 pm

1 stop19h 25m

$263

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Wed 4/29

11:26 am-7:39 am

1 stop20h 13m

Cleveland Hopkins Intl

Fri 5/1

6:32 pm-1:09 pm

1 stop18h 37m

$273
Quickest round-trip

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Wed 4/8

7:00 am-1:19 pm

1 stop6h 19m

Cleveland Hopkins Intl

Wed 4/8

6:00 pm-11:08 pm

1 stop5h 08m

$279

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Thu 3/26

7:00 am-2:27 pm

1 stop7h 27m

Cleveland Hopkins Intl

Mon 3/30

6:45 pm-2:10 pm

1 stop19h 25m

$281

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Wed 4/8

12:50 pm-10:15 pm

2 stops9h 25m

Cleveland Hopkins Intl

Wed 4/15

6:40 am-12:00 pm

1 stop5h 20m

$284

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Sat 7/4

7:00 am-12:55 pm

1 stop5h 55m

Cleveland Hopkins Intl

Sat 7/11

3:35 pm-9:20 pm

1 stop5h 45m

$287

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Wed 4/8

7:05 am-5:25 pm

2 stops10h 20m

Cleveland Hopkins Intl

Wed 4/15

10:30 am-7:40 pm

2 stops9h 10m

$289

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cleveland from

How to get the cheapest flight ticket from Knoxville to Cleveland

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

How have Knoxville to Cleveland flight prices changed over time?

As of March 2026, prices for Knoxville to Cleveland flights are approximately 96% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Cleveland

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Cleveland according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Cleveland (TYS to CLE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Cleveland

Fastest flight time

5h 00m

Direct flights

None
The fastest flight from Knoxville to Cleveland takes 5h 00m
There are no direct flights from Knoxville to Cleveland. There are no popular flight routes from Knoxville to Cleveland.
Search flight deals

  • How far is Knoxville McGhee Tyson to Cleveland Hopkins Intl by plane?

    A flight from Knoxville McGhee Tyson to Cleveland Hopkins Intl will travel around 400.8 mi. 5h 00m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Cleveland Hopkins Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Cleveland Hopkins Intl Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Cleveland Hopkins Intl Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Cleveland Hopkins Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Cleveland Hopkins Intl Airport.

  • What documentation or ID do you need to fly to Cleveland Hopkins Intl Airport?

    The travel and health documents you'll need for your trip to Cleveland Hopkins Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Cleveland Hopkins Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Cleveland?

Best airlines flying from Knoxville to Cleveland

Compare and see reviews for airlines that fly from Knoxville to Cleveland with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $198Free CancellationRating
7.4
9,414 reviews
Search United Airlines flights
American AirlinesPriceFrom $213Free CancellationRating
7.1
11,419 reviews
Search American Airlines flights
DeltaPriceFrom $228Free CancellationRating
7.9
8,278 reviews
Search Delta flights

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Mansfield
Beachwood
Independence
Elyria
Mentor
Geneva-on-the-Lake
Westlake
Kent
Wooster
Streetsboro
Willoughby
Cuyahoga Falls
North Olmsted
Painesville
Medina
Lakewood
Ashland
Kelleys Island
Avon

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Cleveland?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Cleveland. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Cleveland with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Cleveland flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Cleveland?

momondo provides multiple filters to help you find the best flight to Cleveland from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Cleveland right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Cleveland flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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