Cheap flights from Knoxville to Chicago from $49
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Chicago departing on 7/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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How to get the cheapest flight ticket from Knoxville to Chicago
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Chicago?
The month of September is, on average, the cheapest month to fly to Chicago from Knoxville, with most prices found around $178. If you’re not able to fly to Chicago in September, then October is your next best option. Flight prices from Knoxville to Chicago during October average around $202.
What is the cheapest day to depart on your flight to Chicago?
The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $384. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Chicago for around $729.
What is the cheapest time of day to depart on your flight to Chicago?
Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Knoxville to Chicago during this time can be as low as $477. In contrast, the most expensive time of day to depart to Chicago is at noon when prices are around $725.
What is the cheapest Knoxville McGhee Tyson to Chicago flight route?
Fly from Knoxville McGhee Tyson to Chicago Midway for the best Knoxville McGhee Tyson - Chicago flight prices
How far in advance should I book a flight to Chicago?
You are more likely to see cheaper flights to Chicago from Knoxville when booking 17 weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $277 when searching 17 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Knoxville for as low as $202 on momondo.
What cabin class options are available on Knoxville McGhee Tyson to Chicago flights?
There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
Can stopping save me money on Knoxville to Chicago flights?
No. A direct flight is the cheapest option for a flight between Knoxville to Chicago.
How have Knoxville to Chicago flight prices changed over time?
As of June 2025, prices for Knoxville to Chicago flights are approximately 25% more expensive when compared to flights at the same time last year.
What is the cheapest airline that flies from Knoxville McGhee Tyson to Chicago?
Allegiant Air, American Airlines, and Frontier are the most popular carriers operating from Knoxville McGhee Tyson to Chicago
What airlines fly to Chicago?
United Airlines, American Airlines and Delta are the top three most popular airlines that fly to Chicago from Knoxville according to our data. United Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Chicago. Keep in mind that there are 4 different airlines that fly to Chicago on a routine basis, so you have a few additional options to choose from.
How many flights depart from Knoxville to Chicago on average per day?
As of June 2025, 23 flights take off from Knoxville and land in Chicago each day. The most common flight departure time for this route is 1:00PM, with 51% of daily flights taking off in the afternoon.
How many flights depart from Knoxville to Chicago on average per week?
As of June 2025, 164 flights take off from Knoxville and land in Chicago each week. The most common flight departure day for this route is Thu, with 19% of weekly flights taking off on this day.
When to book flights from Knoxville to Chicago
Cheap Knoxville to Chicago (TYS to CHI) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chicago
How far is Knoxville McGhee Tyson to Chicago by plane?
Chicago is 454.2 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 1h 32m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago?
Prices for flights from Knoxville McGhee Tyson Airport to Chicago are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago?
As of June 2025, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Chicago.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chicago.
What documentation or ID do you need to fly to Chicago?
The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Knoxville to Chicago?
Based on momondo bookings for flights between Knoxville and Chicago, the leading plane model is Canadair (Bombardier) Regional Jet CRJ-550, making up 20.24% of the total bookings. Other popular models include Embraer 175 (Enhanced Winglets) with 18.36%, Embraer ERJ-145 with 12.93%, and Airbus A319 with 8.55%.
What is the most popular airline from Knoxville to Chicago?
Based on momondo bookings for flights between Knoxville and Chicago, the leading airline is American Airlines, making up 49% of the total bookings. Other popular airlines include United Airlines with 36% and Allegiant Air with 15%.
Best airlines flying from Knoxville to Chicago
Compare and see reviews for airlines that fly from Knoxville to Chicago with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $75 | Free Cancellation | Rating 7.3 725 reviews | |||
| PriceFrom $165 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $183 | Free Cancellation | Rating 7.4 8,790 reviews | |||
| PriceFrom $233 | Free Cancellation | Rating 8.0 7,950 reviews |
United Airlines Flights From Knoxville to Chicago
United Airlines operates around 20 flights from Knoxville to Chicago every week. The average price of these flights found in the last 72 hours has been $304, but momondo users have found United Airlines deals from Knoxville to Chicago from as low as $183 round-trip. United Airlines has been scored 7.4/10 in 8,790 reviews.
American Airlines Flights From Knoxville to Chicago
American Airlines (7.2/10 from 10,000 reviews) operates around 16 flights from Knoxville to Chicago in any given week. The average American Airlines airfare for this route is around $254, with deals from around $165 rare but found on momondo. Referenced prices are for round-trip Knoxville to Chicago flight searches in the last 72 hours.
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Why should I use momondo to find a flight deal from Knoxville to Chicago?
momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Chicago. Millions of users trust and use momondo every year so you are in good hands.
Can I find flights from Knoxville to Chicago with flexible booking policies on momondo?
Yes. momondo allows you to filter the results for Knoxville to Chicago flights to just show those with flexible booking policies.
How can momondo help me find flights from Knoxville to Chicago?
momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Chicago.
I’m not ready to book a flight from Knoxville to Chicago right now. Can momondo alert me if prices change?
Yes. momondo can track prices for Knoxville to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.