What airlines fly to Chicago?

United Airlines, American Airlines and Delta are the top three most popular airlines that fly to Chicago from Knoxville according to our data. United Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Chicago. Keep in mind that there are 4 different airlines that fly to Chicago on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Chicago?

Allegiant Air and Frontier are the most popular carriers operating from Knoxville McGhee Tyson to Chicago

How many flights depart from Knoxville to Chicago on average per day?

As of August 2025, 17 flights take off from Knoxville and land in Chicago each day. The most common flight departure time for this route is 1:00PM, with 54% of daily flights taking off in the afternoon.

How many flights depart from Knoxville to Chicago on average per week?

As of August 2025, 120 flights take off from Knoxville and land in Chicago each week. The most common flight departure day for this route is Mon, with 26% of weekly flights taking off on this day.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago?

Prices for flights from Knoxville McGhee Tyson Airport to Chicago are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago?

As of August 2025, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Chicago.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chicago.

What documentation or ID do you need to fly to Chicago?

The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$51 Cheap Flights from Knoxville to Chicago (TYS-CHI) in 2025

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Find the cheapest flights from Knoxville to Chicago (TYS-CHI)

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

6:24 pm - 7:00 pmTYS-MDW

1h 36mnonstop

7:50 pm - 10:21 pmMDW-TYS

1h 31mnonstop

$80Allegiant Air

Find Deal

Fri, Sep 12 - Mon, Sep 15

6:24 pm - 7:00 pmTYS-MDW

1h 36mnonstop

7:50 pm - 10:21 pmMDW-TYS

1h 31mnonstop

$82Allegiant Air

Find Deal

Fri, Sep 12 - Mon, Sep 15

4:49 pm - 5:50 pmTYS-ORD

2h 01mnonstop

9:28 am - 12:21 pmORD-TYS

1h 53mnonstop

$189American Airlines

Find Deal

Fri, Sep 12 - Mon, Sep 15

3:04 pm - 4:06 pmTYS-ORD

2h 02mnonstop

1:37 pm - 4:19 pmORD-TYS

1h 42mnonstop

$194American Airlines

Find Deal

Fri, Aug 22 - Fri, Sep 5

10:44 am - 11:16 amTYS-MDW

1h 32mnonstop

4:29 pm - 7:37 pmMDW-TYS

26h 08m1 stop

$197

Find Deal

Fri, Oct 10 - Sun, Oct 12

5:45 am - 9:46 amTYS-ORD

5h 01m1 stop

7:20 am - 10:05 amORD-TYS

1h 45mnonstop

$199United Airlines

Find Deal

Thu, Oct 30 - Sat, Nov 1

7:00 am - 7:55 amTYS-ORD

1h 55mnonstop

2:32 pm - 8:56 pmORD-TYS

5h 24m1 stop

$204United Airlines

Find Deal

Fri, Aug 22 - Fri, Sep 5

8:49 pm - 10:52 amTYS-ORD

15h 03m1 stop

6:44 pm - 11:18 amORD-TYS

15h 34m1 stop

$205

Find Deal

Fri, Sep 5 - Sat, Sep 6

6:08 pm - 9:36 pmTYS-MDW

4h 28m1 stop

12:43 pm - 8:02 pmMDW-TYS

6h 19m1 stop

$209Delta

Find Deal

Fri, Sep 12 - Mon, Sep 15

6:08 pm - 11:54 pmTYS-ORD

6h 46m1 stop

1:22 pm - 9:19 pmORD-TYS

6h 57m1 stop

$209Delta

Find Deal

Fri, Sep 12 - Mon, Sep 15

American Airlines flights from Knoxville to Chicago

Our best American Airlines deals on Knoxville to Chicago flight tickets

American Airlines

Sep 12

TYS4:49 pmKnoxville McGhee Tyson

2h 01m

ORD5:50 pmChicago O'Hare Intl

Sep 15

ORD9:28 amChicago O'Hare Intl

1h 53m

TYS12:21 pmKnoxville McGhee Tyson

$189

Find similar

American Airlines

Aug 22

TYS3:04 pmKnoxville McGhee Tyson

2h 02m

ORD4:06 pmChicago O'Hare Intl

Sep 5

ORD1:37 pmChicago O'Hare Intl

1h 42m

TYS4:19 pmKnoxville McGhee Tyson

$194

Find similar

American Airlines

Sep 11

TYS7:14 amKnoxville McGhee Tyson

2h 04m

ORD8:18 amChicago O'Hare Intl

Sep 14

ORD11:56 amChicago O'Hare Intl

1h 47m

TYS2:43 pmKnoxville McGhee Tyson

$219

Find similar

United Airlines flights from Knoxville to Chicago

Our best United Airlines deals on Knoxville to Chicago flight tickets

United Airlines

Oct 30

TYS5:45 amKnoxville McGhee Tyson

5h 01m

1 stop

ORD9:46 amChicago O'Hare Intl

Nov 1

ORD7:20 amChicago O'Hare Intl

1h 45m

TYS10:05 amKnoxville McGhee Tyson

$199

Find similar

United Airlines

Aug 22

TYS7:00 amKnoxville McGhee Tyson

1h 55m

ORD7:55 amChicago O'Hare Intl

Sep 5

ORD2:32 pmChicago O'Hare Intl

5h 24m

1 stop

TYS8:56 pmKnoxville McGhee Tyson

$204

Find similar

United Airlines

Aug 11

TYS7:00 amKnoxville McGhee Tyson

1h 57m

ORD7:57 amChicago O'Hare Intl

Aug 18

ORD7:50 pmChicago O'Hare Intl

1h 45m

TYS10:35 pmKnoxville McGhee Tyson

$224

Find similar

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/12

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Mon 9/15

7:50 pm-10:21 pm

Nonstop1h 31m

$80

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/12

6:24 pm-7:00 pm

Nonstop1h 36m

Chicago Midway

Mon 9/15

7:50 pm-10:21 pm

Nonstop1h 31m

$82

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 9/12

4:49 pm-5:50 pm

Nonstop2h 01m

Chicago O'Hare Intl

Mon 9/15

9:28 am-12:21 pm

Nonstop1h 53m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 8/22

3:04 pm-4:06 pm

Nonstop2h 02m

Chicago O'Hare Intl

Fri 9/5

1:37 pm-4:19 pm

Nonstop1h 42m

$194

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 10/10

10:44 am-11:16 am

Nonstop1h 32m

Chicago Midway

Sun 10/12

4:29 pm-7:37 pm

1 stop26h 08m

$197

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 10/30

5:45 am-9:46 am

1 stop5h 01m

Chicago O'Hare Intl

Sat 11/1

7:20 am-10:05 am

Nonstop1h 45m

$199

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 8/22

7:00 am-7:55 am

Nonstop1h 55m

Chicago O'Hare Intl

Fri 9/5

2:32 pm-8:56 pm

1 stop5h 24m

$204

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 9/5

8:49 pm-10:52 am

1 stop15h 03m

Chicago O'Hare Intl

Sat 9/6

6:44 pm-11:18 am

1 stop15h 34m

$205

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 9/12

6:08 pm-9:36 pm

1 stop4h 28m

Chicago Midway

Mon 9/15

12:43 pm-8:02 pm

1 stop6h 19m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 9/12

6:08 pm-11:54 pm

1 stop6h 46m

Chicago O'Hare Intl

Mon 9/15

1:22 pm-9:19 pm

1 stop6h 57m

$209

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago?

The month of September is, on average, the cheapest month to fly to Chicago from Knoxville, with most prices found around $189. If you’re not able to fly to Chicago in September, then February is your next best option. Flight prices from Knoxville to Chicago during February average around $206.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $392. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Chicago for around $737.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Knoxville to Chicago during this time can be as low as $486. In contrast, the most expensive time of day to depart to Chicago is in the evening when prices are around $780.

What is the cheapest Knoxville McGhee Tyson to Chicago flight route?

Fly from Knoxville McGhee Tyson to Chicago Midway for the best Knoxville McGhee Tyson - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $274 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Knoxville for as low as $205 on momondo.

What cabin class options are available on Knoxville McGhee Tyson to Chicago flights?

There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Chicago flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Chicago.

How have Knoxville to Chicago flight prices changed over time?

As of August 2025, prices for Knoxville to Chicago flights are approximately 20% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Chicago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Chicago (TYS to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chicago

Best Price Found	$51
Fastest flight time	1h 32m
Direct flights	Every day
Airports in Chicago	2 airports

The best one-way flight to Chicago from Knoxville in the past 72 hours is $51. The best round-trip flight deal from Knoxville to Chicago found on momondo in the last 72 hours is $80.

The fastest flight from Knoxville to Chicago takes 1h 32m

Direct flights go from Knoxville to Chicago every day.

There are 2 airports near Chicago: Chicago O'Hare Intl (ORD), Chicago Midway (MDW)

Search flight deals

How far is Knoxville McGhee Tyson to Chicago by plane?
Chicago is 454.2 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 1h 32m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago?
Prices for flights from Knoxville McGhee Tyson Airport to Chicago are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago?
As of August 2025, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Chicago.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chicago.
What documentation or ID do you need to fly to Chicago?
The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Knoxville to Chicago?
Based on momondo bookings for flights between Knoxville and Chicago, the leading plane model is Canadair (Bombardier) Regional Jet CRJ-550, making up 17.54% of the total bookings. Other popular models include Embraer 175 (Enhanced Winglets) with 17.00%, Canadair (Bombardier) Regional Jet 700 with 15.46%, and Embraer 175 with 11.91%.
What is the most popular airline from Knoxville to Chicago?
Based on momondo bookings for flights between Knoxville and Chicago, the leading airline is American Airlines, making up 51% of the total bookings. Other popular airlines include United Airlines with 34% and Allegiant Air with 15%.

Best airlines flying from Knoxville to Chicago

Compare and see reviews for airlines that fly from Knoxville to Chicago with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $60	Free Cancellation	Rating 7.2 702 reviews	Search Allegiant Air flights
American Airlines	PriceFrom $170	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $186	Free Cancellation	Rating 7.4 8,912 reviews	Search United Airlines flights
Delta	PriceFrom $233	Free Cancellation	Rating 8.0 7,987 reviews	Search Delta flights

United Airlines Flights From Knoxville to Chicago
United Airlines operates around 21 flights from Knoxville to Chicago every week. The average price of these flights found in the last 72 hours has been $299, but momondo users have found United Airlines deals from Knoxville to Chicago from as low as $186 round-trip. United Airlines has been scored 7.4/10 in 8,912 reviews.
Allegiant Air Flights From Knoxville to Chicago
Allegiant Air (7.2/10 from 702 reviews) operates around 2 flights from Knoxville to Chicago in any given week. The average Allegiant Air airfare for this route is around $86, with deals from around $60 rare but found on momondo. Referenced prices are for round-trip Knoxville to Chicago flight searches in the last 72 hours.

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Valparaiso

Crown Point

Munster

Chesterton

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Porter

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Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Chicago.

I’m not ready to book a flight from Knoxville to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Knoxville to Chicago from $51

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Chicago departing on 8/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Find the cheapest flights from Knoxville to Chicago (TYS-CHI)

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American Airlines flights from Knoxville to Chicago

Our best American Airlines deals on Knoxville to Chicago flight tickets

United Airlines flights from Knoxville to Chicago

Our best United Airlines deals on Knoxville to Chicago flight tickets

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How to get the cheapest flight ticket from Knoxville to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of September is, on average, the cheapest month to fly to Chicago from Knoxville, with most prices found around $189. If you’re not able to fly to Chicago in September, then February is your next best option. Flight prices from Knoxville to Chicago during February average around $206.

What is the cheapest day to depart on your flight to Chicago?

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Knoxville to Chicago during this time can be as low as $486. In contrast, the most expensive time of day to depart to Chicago is in the evening when prices are around $780.

What is the cheapest Knoxville McGhee Tyson to Chicago flight route?

Fly from Knoxville McGhee Tyson to Chicago Midway for the best Knoxville McGhee Tyson - Chicago flight prices

How far in advance should I book a flight to Chicago?

What cabin class options are available on Knoxville McGhee Tyson to Chicago flights?

There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Chicago flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Chicago.

How have Knoxville to Chicago flight prices changed over time?

As of August 2025, prices for Knoxville to Chicago flights are approximately 20% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Chicago?

Allegiant Air and Frontier are the most popular carriers operating from Knoxville McGhee Tyson to Chicago

What airlines fly to Chicago?

How many flights depart from Knoxville to Chicago on average per day?

As of August 2025, 17 flights take off from Knoxville and land in Chicago each day. The most common flight departure time for this route is 1:00PM, with 54% of daily flights taking off in the afternoon.

How many flights depart from Knoxville to Chicago on average per week?

As of August 2025, 120 flights take off from Knoxville and land in Chicago each week. The most common flight departure day for this route is Mon, with 26% of weekly flights taking off on this day.

When to book flights from Knoxville to Chicago

Cheap Knoxville to Chicago (TYS to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chicago

Best Price Found

Fastest flight time

Direct flights

Airports in Chicago

How far is Knoxville McGhee Tyson to Chicago by plane?

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago?

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago?

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago?

What documentation or ID do you need to fly to Chicago?

What is the most popular plane model from Knoxville to Chicago?

What is the most popular airline from Knoxville to Chicago?

Best airlines flying from Knoxville to Chicago

Compare and see reviews for airlines that fly from Knoxville to Chicago with momondo

United Airlines Flights From Knoxville to Chicago

Allegiant Air Flights From Knoxville to Chicago

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Chicago?

Can I find flights from Knoxville to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from Knoxville to Chicago?

I’m not ready to book a flight from Knoxville to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago