What is the cheapest airline that flies from Knoxville McGhee Tyson to Chicago?

Allegiant Air, Frontier, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Chicago

How many flights depart from Knoxville to Chicago on average per week?

As of November 2025, 194 flights take off from Knoxville and land in Chicago each week. The most common flight departure day for this route is Wed, with 17% of weekly flights taking off on this day.

How many flights depart from Knoxville to Chicago on average per day?

As of November 2025, 27 flights take off from Knoxville and land in Chicago each day. The most common flight departure time for this route is 1:00PM, with 62% of daily flights taking off in the afternoon.

What airlines fly to Chicago?

United Airlines, American Airlines and Delta are the top three most popular airlines that fly to Chicago from Knoxville according to our data. United Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Chicago. Keep in mind that there are 4 different airlines that fly to Chicago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago?

Prices for flights from Knoxville McGhee Tyson Airport to Chicago are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago?

As of November 2025, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Chicago.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chicago.

What documentation or ID do you need to fly to Chicago?

The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$53 Cheap Flights from Knoxville to Chicago in 2025/26

Q: What is the typical price of a round-trip flight between Knoxville and Chicago?

Prices are currently low for flights on this route. Typical prices usually range from $199 to $409. The lowest price recently found on this route was $180.

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3:22 pm - 11:29 pmTYS-MDW

9h 07m1 stop

2:11 pm - 4:36 pmMDW-TYS

1h 25mnonstop

$180Multiple Airlines

Find Deal

Fri, Nov 21 - Mon, Nov 24

6:09 pm - 2:21 pmTYS-ORD

21h 12m1 stop

7:35 am - 5:53 pmORD-TYS

9h 18m1 stop

$182Multiple Airlines

Find Deal

Wed, Dec 10 - Sun, Jan 18

2:58 pm - 4:06 pmTYS-ORD

2h 08mnonstop

3:08 pm - 5:58 pmORD-TYS

1h 50mnonstop

$189American Airlines

Find Deal

Thu, Dec 4 - Mon, Dec 15

5:34 pm - 11:08 amTYS-ORD

18h 34m2 stops

7:00 am - 3:57 pmORD-TYS

7h 57m1 stop

$190Multiple Airlines

Find Deal

Mon, Dec 8 - Thu, Dec 11

12:45 pm - 1:21 pmTYS-MDW

1h 36mnonstop

6:05 am - 10:03 pmMDW-TYS

14h 58m2 stops

$193Multiple Airlines

Find Deal

Fri, Nov 21 - Sun, Nov 23

7:54 am - 9:00 amTYS-ORD

2h 06mnonstop

3:08 pm - 5:58 pmORD-TYS

1h 50mnonstop

$204American Airlines

Find Deal

Thu, Nov 27 - Fri, Dec 5

7:59 pm - 11:47 pmTYS-MDW

4h 48m1 stop

1:28 pm - 8:47 pmMDW-TYS

6h 19m1 stop

$209Delta

Find Deal

Mon, Dec 8 - Mon, Jan 19

12:50 pm - 6:27 pmTYS-ORD

6h 37m1 stop

5:59 pm - 11:28 pmORD-TYS

4h 29m1 stop

$209Delta

Find Deal

Fri, Dec 12 - Mon, Dec 15

5:49 pm - 6:46 pmTYS-MDW

25h 57m2 stops

2:11 pm - 4:36 pmMDW-TYS

1h 25mnonstop

$210Allegiant Air

Find Deal

Thu, Nov 20 - Mon, Nov 24

12:45 pm - 1:21 pmTYS-MDW

1h 36mnonstop

7:36 pm - 12:16 pmMDW-TYS

39h 40m2 stops

$218Allegiant Air

Find Deal

Fri, Nov 21 - Mon, Nov 24

American Airlines flights from Knoxville to Chicago

Our best American Airlines deals on Knoxville to Chicago flight tickets

American Airlines

May 1

TYS8:23 pmKnoxville McGhee Tyson

2h 07m

ORD9:30 pmChicago O'Hare Intl

May 4

ORD8:20 pmChicago O'Hare Intl

1h 46m

TYS11:06 pmKnoxville McGhee Tyson

$189

Find similar

American Airlines

Feb 12

TYS7:40 amKnoxville McGhee Tyson

2h 13m

ORD8:53 amChicago O'Hare Intl

Feb 15

ORD8:00 amChicago O'Hare Intl

1h 44m

TYS10:44 amKnoxville McGhee Tyson

$193

Find similar

American Airlines

Nov 27

TYS7:54 amKnoxville McGhee Tyson

2h 06m

ORD9:00 amChicago O'Hare Intl

Dec 5

ORD3:08 pmChicago O'Hare Intl

1h 50m

TYS5:58 pmKnoxville McGhee Tyson

$204

Find similar

Delta flights from Knoxville to Chicago

Our best Delta deals on Knoxville to Chicago flight tickets

Delta

Dec 12

TYS7:59 pmKnoxville McGhee Tyson

5h 02m

1 stop

ORD12:01 amChicago O'Hare Intl

Dec 14

ORD6:45 amChicago O'Hare Intl

5h 59m

1 stop

TYS1:44 pmKnoxville McGhee Tyson

$209

Find similar

Delta

Nov 27

TYS2:49 pmKnoxville McGhee Tyson

5h 03m

1 stop

ORD6:52 pmChicago O'Hare Intl

Dec 5

ORD5:59 pmChicago O'Hare Intl

4h 29m

1 stop

TYS11:28 pmKnoxville McGhee Tyson

$224

Find similar

Delta

Dec 12

TYS7:59 pmKnoxville McGhee Tyson

4h 48m

1 stop

MDW11:47 pmChicago Midway

Jan 17

MDW6:45 amChicago Midway

6h 07m

1 stop

TYS1:52 pmKnoxville McGhee Tyson

$234

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Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 11/21

3:22 pm-11:29 pm

1 stop9h 07m

Chicago Midway

Mon 11/24

2:11 pm-4:36 pm

Nonstop1h 25m

$180

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 12/10

6:09 pm-2:21 pm

1 stop21h 12m

Chicago O'Hare Intl

Sun 1/18

7:35 am-5:53 pm

1 stop9h 18m

$182

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 12/4

2:58 pm-4:06 pm

Nonstop2h 08m

Chicago O'Hare Intl

Mon 12/15

3:08 pm-5:58 pm

Nonstop1h 50m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Mon 12/8

5:34 pm-11:08 am

2 stops18h 34m

Chicago O'Hare Intl

Thu 12/11

7:00 am-3:57 pm

1 stop7h 57m

$190

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 11/21

12:45 pm-1:21 pm

Nonstop1h 36m

Chicago Midway

Sun 11/23

6:05 am-10:03 pm

2 stops14h 58m

$193

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 11/27

7:54 am-9:00 am

Nonstop2h 06m

Chicago O'Hare Intl

Fri 12/5

3:08 pm-5:58 pm

Nonstop1h 50m

$204

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Mon 12/8

7:59 pm-11:47 pm

1 stop4h 48m

Chicago Midway

Mon 1/19

1:28 pm-8:47 pm

1 stop6h 19m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 12/12

12:50 pm-6:27 pm

1 stop6h 37m

Chicago O'Hare Intl

Mon 12/15

5:59 pm-11:28 pm

1 stop4h 29m

$209

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 11/20

5:49 pm-6:46 pm

2 stops25h 57m

Chicago Midway

Mon 11/24

2:11 pm-4:36 pm

Nonstop1h 25m

$210

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 11/21

12:45 pm-1:21 pm

Nonstop1h 36m

Chicago Midway

Mon 11/24

7:36 pm-12:16 pm

2 stops39h 40m

$218

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How to get the cheapest flight ticket from Knoxville to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the typical price of a round-trip flight between Knoxville and Chicago?

What is the cheapest month to fly to Chicago?

The month of February is, on average, the cheapest month to fly to Chicago from Knoxville, with most prices found around $209. If you’re not able to fly to Chicago in February, then August is your next best option. Flight prices from Knoxville to Chicago during August average around $219.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $378. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Chicago for around $759.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Knoxville to Chicago during this time can be as low as $487. In contrast, the most expensive time of day to depart to Chicago is in the evening when prices are around $848.

What is the cheapest Knoxville McGhee Tyson to Chicago flight route?

Fly from Knoxville McGhee Tyson to Chicago Midway for the best Knoxville McGhee Tyson - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $288 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Knoxville for as low as $205 on momondo.

What cabin class options are available on Knoxville McGhee Tyson to Chicago flights?

There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Chicago flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Chicago.

How have Knoxville to Chicago flight prices changed over time?

As of November 2025, prices for Knoxville to Chicago flights are approximately 41% cheaper when compared to flights at the same time last year.

When to book flights from Knoxville to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Chicago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Chicago (TYS to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chicago

Best Price Found	$77
Fastest flight time	1h 36m
Direct flights	Every day
Airports in Chicago	2 airports

The best one-way flight to Chicago from Knoxville in the past 72 hours is $77. The best round-trip flight deal from Knoxville to Chicago found on momondo in the last 72 hours is $96.

The fastest flight from Knoxville to Chicago takes 1h 36m

Direct flights go from Knoxville to Chicago every day.

There are 2 airports near Chicago: Chicago O'Hare Intl (ORD), Chicago Midway (MDW)

Search flight deals

How far is Knoxville McGhee Tyson to Chicago by plane?
Chicago is 454.2 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 1h 36m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago?
Prices for flights from Knoxville McGhee Tyson Airport to Chicago are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago?
As of November 2025, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Chicago.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chicago.
What documentation or ID do you need to fly to Chicago?
The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Knoxville to Chicago?
Based on momondo bookings for flights between Knoxville and Chicago, the leading plane model is Canadair (Bombardier) Regional Jet 700, making up 18.51% of the total bookings. Other popular models include Canadair (Bombardier) Regional Jet CRJ-550 with 17.46%, Embraer 175 (Enhanced Winglets) with 14.29%, and Embraer 170 with 12.60%.
What is the most popular airline from Knoxville to Chicago?
Based on momondo bookings for flights between Knoxville and Chicago, the leading airline is American Airlines, making up 49% of the total bookings. Other popular airlines include United Airlines with 36% and Allegiant Air with 15%.

Best airlines flying from Knoxville to Chicago

Compare and see reviews for airlines that fly from Knoxville to Chicago with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $60	Free Cancellation	Rating 7.2 698 reviews	Search Allegiant Air flights
American Airlines	PriceFrom $189	Free Cancellation	Rating 7.2 11,051 reviews	Search American Airlines flights
United Airlines	PriceFrom $189	Free Cancellation	Rating 7.4 9,017 reviews	Search United Airlines flights
Delta	PriceFrom $258	Free Cancellation	Rating 7.9 8,007 reviews	Search Delta flights

United Airlines Flights From Knoxville to Chicago
United Airlines operates around 29 flights from Knoxville to Chicago every week. The average price of these flights found in the last 72 hours has been $317, but momondo users have found United Airlines deals from Knoxville to Chicago from as low as $189 round-trip. United Airlines has been scored 7.4/10 in 9,017 reviews.
American Airlines Flights From Knoxville to Chicago
American Airlines (7.2/10 from 11,051 reviews) operates around 20 flights from Knoxville to Chicago in any given week. The average American Airlines airfare for this route is around $266, with deals from around $189 rare but found on momondo. Referenced prices are for round-trip Knoxville to Chicago flight searches in the last 72 hours.

Merrillville

New Buffalo

Hammond

Benton Harbor

Saint Joseph

Portage

Lansing

Schererville

Valparaiso

Crown Point

Munster

Chesterton

Monticello

Porter

Griffith

Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Chicago.

I’m not ready to book a flight from Knoxville to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Knoxville to Chicago from $53

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Chicago departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Knoxville to Chicago

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How to get the cheapest flight ticket from Knoxville to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Chicago?

What is the cheapest month to fly to Chicago?

The month of February is, on average, the cheapest month to fly to Chicago from Knoxville, with most prices found around $209. If you’re not able to fly to Chicago in February, then August is your next best option. Flight prices from Knoxville to Chicago during August average around $219.

What is the cheapest day to depart on your flight to Chicago?

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Knoxville to Chicago during this time can be as low as $487. In contrast, the most expensive time of day to depart to Chicago is in the evening when prices are around $848.

What is the cheapest Knoxville McGhee Tyson to Chicago flight route?

Fly from Knoxville McGhee Tyson to Chicago Midway for the best Knoxville McGhee Tyson - Chicago flight prices

How far in advance should I book a flight to Chicago?

What cabin class options are available on Knoxville McGhee Tyson to Chicago flights?

There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Chicago flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Chicago.

How have Knoxville to Chicago flight prices changed over time?

As of November 2025, prices for Knoxville to Chicago flights are approximately 41% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Chicago?

Allegiant Air, Frontier, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Chicago

What airlines fly to Chicago?

How many flights depart from Knoxville to Chicago on average per day?

As of November 2025, 27 flights take off from Knoxville and land in Chicago each day. The most common flight departure time for this route is 1:00PM, with 62% of daily flights taking off in the afternoon.

How many flights depart from Knoxville to Chicago on average per week?

As of November 2025, 194 flights take off from Knoxville and land in Chicago each week. The most common flight departure day for this route is Wed, with 17% of weekly flights taking off on this day.

When to book flights from Knoxville to Chicago

Cheap Knoxville to Chicago (TYS to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chicago

Best Price Found

Fastest flight time

Direct flights

Airports in Chicago

How far is Knoxville McGhee Tyson to Chicago by plane?

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chicago?

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chicago?

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chicago?

What documentation or ID do you need to fly to Chicago?

What is the most popular plane model from Knoxville to Chicago?

What is the most popular airline from Knoxville to Chicago?

Best airlines flying from Knoxville to Chicago

Compare and see reviews for airlines that fly from Knoxville to Chicago with momondo

United Airlines Flights From Knoxville to Chicago

American Airlines Flights From Knoxville to Chicago

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Chicago?

Can I find flights from Knoxville to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from Knoxville to Chicago?

I’m not ready to book a flight from Knoxville to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago