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Cheap flights from Islip, New York to St. Louis from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to St. Louis departing on 9/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Islip, New York to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
12:35 pm - 9:45 pmISP  Islip Long Island-STL Lambert-St Louis
10h 10m1 stop Baltimore/Washington
Southwest Logo
6:45 am - 2:30 pmSTL  Lambert-St Louis-ISP Islip Long Island
6h 45m1 stop Baltimore/Washington
$220Southwest
Thu, Sep 24 - Sat, Sep 26
Southwest Logo
2:00 pm - 8:50 pmISP  Islip Long Island-STL Lambert-St Louis
7h 50m1 stop Orlando
Southwest Logo
1:40 pm - 9:10 pmSTL  Lambert-St Louis-ISP Islip Long Island
6h 30m1 stop Baltimore/Washington
$223Southwest
Sat, Sep 5 - Tue, Sep 8
Southwest Logo
12:35 pm - 9:45 pmISP  Islip Long Island-STL Lambert-St Louis
10h 10m1 stop Baltimore/Washington
Southwest Logo
5:45 am - 2:30 pmSTL  Lambert-St Louis-ISP Islip Long Island
7h 45m2 stops Chicago Midway Baltimore/Washington
$225Southwest
Thu, Sep 24 - Sat, Sep 26
Frontier Logo
5:43 pm - 4:34 pmISP  Islip Long Island-STL Lambert-St Louis
23h 51m1 stop Orlando
Frontier Logo
5:19 pm - 4:58 pmSTL  Lambert-St Louis-ISP Islip Long Island
22h 39m1 stop Orlando
$239Frontier
Thu, Sep 24 - Sun, Sep 27
Southwest Logo
6:10 am - 11:35 amISP  Islip Long Island-STL Lambert-St Louis
6h 25m1 stop Baltimore/Washington
Southwest Logo
1:40 pm - 9:10 pmSTL  Lambert-St Louis-ISP Islip Long Island
6h 30m1 stop Baltimore/Washington
$262Southwest
Fri, Sep 4 - Tue, Sep 8
Frontier Logo
5:43 pm - 4:34 pmISP  Islip Long Island-STL Lambert-St Louis
23h 51m1 stop Orlando
Frontier Logo
2:29 pm - 4:58 pmSTL  Lambert-St Louis-ISP Islip Long Island
25h 29m2 stops Atlanta Hartsfield-Jackson Orlando
$273Frontier
Thu, Sep 24 - Mon, Sep 28
Southwest Logo
1:15 pm - 10:30 pmISP  Islip Long Island-STL Lambert-St Louis
10h 15m2 stops Palm Beach Intl Orlando
Southwest Logo
6:45 am - 2:30 pmSTL  Lambert-St Louis-ISP Islip Long Island
6h 45m1 stop Baltimore/Washington
$274Southwest
Thu, Sep 24 - Sat, Sep 26
Southwest Logo
5:30 am - 10:50 amISP  Islip Long Island-STL Lambert-St Louis
6h 20m1 stop Baltimore/Washington
Southwest Logo
6:45 am - 2:30 pmSTL  Lambert-St Louis-ISP Islip Long Island
6h 45m1 stop Baltimore/Washington
$282Southwest
Sat, Sep 5 - Sat, Sep 12
Southwest Logo
5:00 pm - 10:30 pmISP  Islip Long Island-STL Lambert-St Louis
6h 30m1 stop Orlando
Southwest Logo
5:55 am - 12:10 pmSTL  Lambert-St Louis-ISP Islip Long Island
5h 15m1 stop Baltimore/Washington
$282Southwest
Fri, Sep 11 - Tue, Sep 15
Frontier Logo
5:43 pm - 5:54 pmISP  Islip Long Island-STL Lambert-St Louis
25h 11m1 stop Orlando
Frontier Logo
10:35 am - 9:33 amSTL  Lambert-St Louis-ISP Islip Long Island
21h 58m2 stops Atlanta Hartsfield-Jackson Orlando
$286Frontier
Wed, Sep 30 - Wed, Nov 4

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Southwest flights from Islip, New York to St. Louis

Our best Southwest deals on Islip, New York to St. Louis flight tickets
Southwest
Sep 24
ISP12:35 pmIslip Long Island
10h 10m
1 stop
STL9:45 pmLambert-St Louis
Sep 26
STL6:45 amLambert-St Louis
6h 45m
1 stop
ISP2:30 pmIslip Long Island
$220
Southwest
Sep 5
ISP2:00 pmIslip Long Island
7h 50m
1 stop
STL8:50 pmLambert-St Louis
Sep 8
STL1:40 pmLambert-St Louis
6h 30m
1 stop
ISP9:10 pmIslip Long Island
$223
Southwest
Sep 24
ISP12:35 pmIslip Long Island
10h 10m
1 stop
STL9:45 pmLambert-St Louis
Sep 26
STL5:45 amLambert-St Louis
7h 45m
2 stops
ISP2:30 pmIslip Long Island
$225

Frontier flights from Islip, New York to St. Louis

Our best Frontier deals on Islip, New York to St. Louis flight tickets
Frontier
Sep 24
ISP5:43 pmIslip Long Island
23h 51m
1 stop
STL4:34 pmLambert-St Louis
Sep 27
STL5:19 pmLambert-St Louis
22h 39m
1 stop
ISP4:58 pmIslip Long Island
$239
Frontier
Sep 24
ISP5:43 pmIslip Long Island
23h 51m
1 stop
STL4:34 pmLambert-St Louis
Sep 28
STL2:29 pmLambert-St Louis
25h 29m
2 stops
ISP4:58 pmIslip Long Island
$273
Frontier
Sep 30
ISP5:43 pmIslip Long Island
25h 11m
1 stop
STL5:54 pmLambert-St Louis
Nov 4
STL10:35 amLambert-St Louis
21h 58m
2 stops
ISP9:33 amIslip Long Island
$286

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Islip, New York to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Thu 9/24

12:35 pm-9:45 pm

1 stop10h 10m

Lambert-St Louis

Sat 9/26

6:45 am-2:30 pm

1 stop6h 45m

$220

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Sat 9/5

2:00 pm-8:50 pm

1 stop7h 50m

Lambert-St Louis

Tue 9/8

1:40 pm-9:10 pm

1 stop6h 30m

$223

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Thu 9/24

12:35 pm-9:45 pm

1 stop10h 10m

Lambert-St Louis

Sat 9/26

5:45 am-2:30 pm

2 stops7h 45m

$225

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Thu 9/24

5:43 pm-4:34 pm

1 stop23h 51m

Lambert-St Louis

Sun 9/27

5:19 pm-4:58 pm

1 stop22h 39m

$239

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Fri 9/4

6:10 am-11:35 am

1 stop6h 25m

Lambert-St Louis

Tue 9/8

1:40 pm-9:10 pm

1 stop6h 30m

$262

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Thu 9/24

5:43 pm-4:34 pm

1 stop23h 51m

Lambert-St Louis

Mon 9/28

2:29 pm-4:58 pm

2 stops25h 29m

$273

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Thu 9/24

1:15 pm-10:30 pm

2 stops10h 15m

Lambert-St Louis

Sat 9/26

6:45 am-2:30 pm

1 stop6h 45m

$274

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Sat 9/5

5:30 am-10:50 am

1 stop6h 20m

Lambert-St Louis

Sat 9/12

6:45 am-2:30 pm

1 stop6h 45m

$282
Quickest round-trip

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Fri 9/11

5:00 pm-10:30 pm

1 stop6h 30m

Lambert-St Louis

Tue 9/15

5:55 am-12:10 pm

1 stop5h 15m

$282

IslipSt. Louis

ISP Islip Long Island - STL Lambert-St Louis

ISPSTL

Islip Long Island

Wed 9/30

5:43 pm-5:54 pm

1 stop25h 11m

Lambert-St Louis

Wed 11/4

10:35 am-9:33 am

2 stops21h 58m

$286

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Islip, New York to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $379. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $492. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Islip, New York in the evening is the least expensive time of day to depart. momondo users have found prices as low as $385 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $424 per ticket.

When to book flights from Islip, New York to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Islip, New York to St. Louis (ISP to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to St. Louis

Fastest flight time

6h 35m

Direct flights

None
The fastest flight from Islip, New York to St. Louis takes 6h 35m
There are no direct flights from Islip, New York to St. Louis. There are no popular flight routes from Islip, New York to St. Louis.
Search flight deals

Frequently asked questions about flying from Islip, New York to St. Louis

  • How far is Islip Long Island to Lambert-St Louis by plane?

    There are 912.8 mi between Islip Long Island and Lambert-St Louis. In terms of flight time, this usually takes a little over 6h 35m.

  • When did momondo last update prices for flights from Islip Long Island Airport to Lambert-St Louis Airport?

    Prices for flights from Islip Long Island Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Islip Long Island Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Islip Long Island Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents you'll need for your trip to Lambert-St Louis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Lambert-St Louis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Islip, New York to St. Louis?

Best airlines flying from Islip, New York to St. Louis

Compare and see reviews for airlines that fly from Islip, New York to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $246Free CancellationRating
8.0
4,221 reviews
Search Southwest flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
St. Peters
Maryland Heights
Collinsville
Florissant
Alton
O'Fallon
Farmington
Clayton
Fenton
Festus
Wentzville
Eureka
Edwardsville
Litchfield
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Islip to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Islip to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Islip to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Islip to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Islip to St. Louis?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Islip to St. Louis.

I’m not ready to book a flight from Islip to St. Louis right now. Can momondo alert me if prices change?

Price alerts on flights to St. Louis from Islip are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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