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Cheap flights from Islip, New York to South Carolina from $60

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to South Carolina departing on 5/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Islip, New York to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
2:33 pm - 4:41 pm
ISP
-
CHS
2h 08mnonstop
Breeze Airways Logo
6:06 pm - 8:03 pm
CHS
-
ISP
1h 57mnonstop
$122Breeze Airways
Sat, Jul 25 - Mon, Jul 27
Breeze Airways Logo
8:45 pm - 10:57 pm
ISP
-
CHS
2h 12mnonstop
Breeze Airways Logo
6:06 pm - 8:03 pm
CHS
-
ISP
1h 57mnonstop
$127Breeze Airways
Mon, May 4 - Fri, May 8
Breeze Airways Logo
8:45 pm - 10:57 pm
ISP
-
CHS
2h 12mnonstop
Breeze Airways Logo
6:11 pm - 8:05 pm
CHS
-
ISP
1h 54mnonstop
$132Breeze Airways
Fri, Mar 13 - Mon, Mar 16
Breeze Airways Logo
8:45 pm - 10:57 pm
ISP
-
CHS
2h 12mnonstop
Breeze Airways Logo
6:11 pm - 8:05 pm
CHS
-
ISP
1h 54mnonstop
$134Breeze Airways
Fri, Mar 13 - Mon, Mar 16
Frontier Logo
10:08 am - 12:06 pm
ISP
-
MYR
1h 58mnonstop
Frontier Logo
1:21 pm - 3:12 pm
MYR
-
ISP
1h 51mnonstop
$175Frontier
Thu, Apr 23 - Mon, Apr 27
Frontier Logo
10:08 am - 12:06 pm
ISP
-
MYR
1h 58mnonstop
Frontier Logo
1:21 pm - 3:12 pm
MYR
-
ISP
1h 51mnonstop
$176Frontier
Thu, Apr 16 - Mon, Apr 20
Multiple Airlines Logo
3:59 pm - 1:51 pm
ISP
-
CLT
21h 52m
1 stop
Multiple Airlines Logo
9:07 pm - 11:42 pm
CLT
-
ISP
26h 35m
2 stops
$193Multiple Airlines
Mon, Feb 23 - Mon, Mar 2
Multiple Airlines Logo
3:34 pm - 7:58 am
ISP
-
CLT
16h 24m
1 stop
Multiple Airlines Logo
10:42 pm - 11:10 am
CLT
-
ISP
36h 28m
2 stops
$200Multiple Airlines
Thu, Feb 19 - Mon, Feb 23
Southwest Logo
4:30 pm - 9:20 pm
ISP
-
SAV
4h 50m
1 stop
Southwest Logo
8:05 am - 11:55 am
SAV
-
ISP
3h 50m
1 stop
$314Southwest
Mon, Apr 13 - Wed, Apr 15
Southwest Logo
4:40 pm - 9:35 pm
ISP
-
GSP
4h 55m
1 stop
Southwest Logo
8:20 am - 11:55 am
GSP
-
ISP
3h 35m
1 stop
$314Southwest
Sat, Apr 18 - Tue, Apr 21

Frontier flights from Islip, New York to South Carolina

Our best Frontier deals on Islip, New York to South Carolina flight tickets
Frontier
Apr 23
ISP10:08 amIslip Long Island
1h 58m
MYR12:06 pmMyrtle Beach Intl
Apr 27
MYR1:21 pmMyrtle Beach Intl
1h 51m
ISP3:12 pmIslip Long Island
$175
Frontier
Apr 16
ISP10:08 amIslip Long Island
1h 58m
MYR12:06 pmMyrtle Beach Intl
Apr 20
MYR1:21 pmMyrtle Beach Intl
1h 51m
ISP3:12 pmIslip Long Island
$176
Frontier
Feb 26
ISP3:34 pmIslip Long Island
16h 24m
1 stop
CLT7:58 amCharlotte Douglas
Mar 1
CLT9:52 pmCharlotte Douglas
9h 46m
1 stop
ISP7:38 amIslip Long Island
$189

Southwest flights from Islip, New York to South Carolina

Our best Southwest deals on Islip, New York to South Carolina flight tickets
Southwest
Apr 17
ISP4:30 pmIslip Long Island
5h 05m
1 stop
CLT9:35 pmCharlotte Douglas
Apr 20
CLT7:20 pmCharlotte Douglas
4h 10m
1 stop
ISP11:30 pmIslip Long Island
$266
Southwest
Mar 9
ISP6:00 amIslip Long Island
4h 00m
1 stop
MYR10:00 amMyrtle Beach Intl
Mar 12
MYR8:05 pmMyrtle Beach Intl
3h 50m
1 stop
ISP11:55 pmIslip Long Island
$267
Southwest
May 5
ISP6:30 amIslip Long Island
7h 00m
2 stops
MYR1:30 pmMyrtle Beach Intl
May 9
MYR7:15 pmMyrtle Beach Intl
4h 05m
1 stop
ISP11:20 pmIslip Long Island
$272

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Islip, New York to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Sat 7/25

2:33 pm-4:41 pm

Nonstop2h 08m

Charleston

Mon 7/27

6:06 pm-8:03 pm

Nonstop1h 57m

$122

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Mon 5/4

8:45 pm-10:57 pm

Nonstop2h 12m

Charleston

Fri 5/8

6:06 pm-8:03 pm

Nonstop1h 57m

$127

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 3/13

8:45 pm-10:57 pm

Nonstop2h 12m

Charleston

Mon 3/16

6:11 pm-8:05 pm

Nonstop1h 54m

$132

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 3/13

8:45 pm-10:57 pm

Nonstop2h 12m

Charleston

Mon 3/16

6:11 pm-8:05 pm

Nonstop1h 54m

$134

IslipMyrtle Beach

ISP - MYR

ISPMYR

Islip Long Island

Thu 4/23

10:08 am-12:06 pm

Nonstop1h 58m

Myrtle Beach Intl

Mon 4/27

1:21 pm-3:12 pm

Nonstop1h 51m

$175

IslipMyrtle Beach

ISP - MYR

ISPMYR

Islip Long Island

Thu 4/16

10:08 am-12:06 pm

Nonstop1h 58m

Myrtle Beach Intl

Mon 4/20

1:21 pm-3:12 pm

Nonstop1h 51m

$176

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Mon 2/23

3:59 pm-1:51 pm

1 stop21h 52m

Charlotte Douglas

Mon 3/2

9:07 pm-11:42 pm

2 stops26h 35m

$193

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Thu 2/19

3:34 pm-7:58 am

1 stop16h 24m

Charlotte Douglas

Mon 2/23

10:42 pm-11:10 am

2 stops36h 28m

$200

IslipSavannah

ISP - SAV

ISPSAV

Islip Long Island

Mon 4/13

4:30 pm-9:20 pm

1 stop4h 50m

Savannah/Hilton Head

Wed 4/15

8:05 am-11:55 am

1 stop3h 50m

$314

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Sat 4/18

4:40 pm-9:35 pm

1 stop4h 55m

Greenville

Tue 4/21

8:20 am-11:55 am

1 stop3h 35m

$314

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Islip, New York to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Islip, New York is in March. Flight prices, which tend to average around $165, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to South Carolina from Islip, New York during May instead. Flights to South Carolina in May, while not as cheap as those in March, still average around $167.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Thursday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $146. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $233.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Islip, New York to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $183. Try not to purchase tickets at noon because they tend to be around $201. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Islip Long Island to South Carolina flight route?

Fly from Islip Long Island to Charleston for the best Islip Long Island - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Islip, New York when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $212 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Islip, New York for as low as $79 on momondo.

What cabin class options are available on Islip Long Island to South Carolina flights?

There is only 1 cabin class available to choose from on Islip Long Island to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Islip, New York to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Islip, New York to South Carolina.

Cheap Islip, New York to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to South Carolina

Best Price Found

$54

Fastest flight time

1h 55m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Islip, New York in the past 72 hours is $54. The best round-trip flight deal from Islip, New York to South Carolina found on momondo in the last 72 hours is $163.
The fastest flight from Islip, New York to South Carolina takes 1h 55m
Direct flights go from Islip, New York to South Carolina on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Breeze Airways.
There are 57 airports in South Carolina. From Islip, New York there are direct flights to Myrtle Beach Intl (MYR), Charleston (CHS).
Search flight deals

  • When did momondo last update prices for flights from Islip Long Island Airport to South Carolina?

    Prices for flights from Islip Long Island Airport to South Carolina were last updated today.

  • How many operators does momondo search for flights from Islip Long Island Airport to South Carolina?

  • How old do you have to be to fly from Islip Long Island Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Islip, New York to South Carolina?

Best airlines flying from Islip, New York to South Carolina

Compare and see reviews for airlines that fly from Islip, New York to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $77Free CancellationRating
6.3
8,421 reviews
Search Spirit Airlines flights
Breeze AirwaysPriceFrom $94Free CancellationRating
8.1
266 reviews
Search Breeze Airways flights
FrontierPriceFrom $107Free CancellationRating
5.7
3,054 reviews
Search Frontier flights
JetBluePriceFrom $162Free CancellationRating
7.2
2,898 reviews
Search JetBlue flights
SouthwestPriceFrom $218Free CancellationRating
8.0
4,280 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Islip to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Islip to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Islip to South Carolina with flexible booking policies on momondo?

All flight searches from Islip to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Islip to South Carolina?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Islip to South Carolina.

I’m not ready to book a flight from Islip to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Islip and alert you when they change.

An easier way to manage your South Carolina trip

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