What airlines fly to Knoxville?

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Knoxville from Islip according to our data. American Airlines is the first choice among our users, with 35% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Islip Long Island Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Islip Long Island Airport to Knoxville McGhee Tyson Airport were last updated today.

How old do you have to be to fly from Islip Long Island Airport to Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$183 Cheap Flights from Islip to Knoxville in 2025

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Find the cheapest flights from Islip to Knoxville

Round-trip

One-way

Last minute

Cheap round-trip flights

5:05 pm - 10:35 amISP-TYS

17h 30m1 stop

6:34 pm - 10:40 amTYS-ISP

16h 06m1 stop

$231

Find Deal

Mon, Sep 15 - Mon, Sep 22

5:05 pm - 10:35 amISP-TYS

17h 30m1 stop

1:22 pm - 10:40 amTYS-ISP

21h 18m1 stop

$236

Find Deal

Mon, Sep 15 - Mon, Sep 22

5:05 pm - 3:41 pmISP-TYS

46h 36m2 stops

6:34 pm - 10:40 amTYS-ISP

16h 06m1 stop

$271

Find Deal

Mon, Sep 15 - Mon, Sep 22

5:05 pm - 3:41 pmISP-TYS

46h 36m2 stops

1:22 pm - 10:40 amTYS-ISP

21h 18m1 stop

$276

Find Deal

Mon, Sep 15 - Mon, Sep 22

6:37 pm - 12:18 pmISP-TYS

17h 41m1 stop

7:17 pm - 5:42 pmTYS-ISP

22h 25m2 stops

$293

Find Deal

Thu, Oct 30 - Mon, Nov 3

4:58 pm - 3:06 pmISP-TYS

22h 08m1 stop

5:59 pm - 5:42 pmTYS-ISP

23h 43m1 stop

$309

Find Deal

Mon, Oct 27 - Mon, Nov 3

11:45 am - 11:08 pmISP-TYS

11h 23m2 stops

1:22 pm - 10:40 amTYS-ISP

21h 18m1 stop

$313

Find Deal

Thu, Sep 4 - Mon, Sep 8

4:58 pm - 3:06 pmISP-TYS

22h 08m1 stop

7:17 pm - 10:37 amTYS-ISP

39h 20m2 stops

$340

Find Deal

Mon, Oct 27 - Mon, Nov 3

9:37 pm - 7:32 pmISP-TYS

21h 55m2 stops

8:17 pm - 10:37 amTYS-ISP

14h 20m2 stops

$617Frontier

Find Deal

Thu, Oct 23 - Sun, Oct 26

9:37 pm - 7:32 pmISP-TYS

21h 55m2 stops

8:17 pm - 10:37 amTYS-ISP

14h 20m2 stops

$987Frontier

Find Deal

Thu, Oct 16 - Sun, Oct 19

Frontier flights from Islip to Knoxville

Our best Frontier deals on Islip to Knoxville flight tickets

Frontier

Oct 23

ISP9:37 pmIslip Long Island

21h 55m

2 stops

TYS7:32 pmKnoxville McGhee Tyson

Oct 26

TYS8:17 pmKnoxville McGhee Tyson

14h 20m

2 stops

ISP10:37 amIslip Long Island

$617

Find similar

Frontier

Oct 16

ISP9:37 pmIslip Long Island

21h 55m

2 stops

TYS7:32 pmKnoxville McGhee Tyson

Oct 19

TYS8:17 pmKnoxville McGhee Tyson

14h 20m

2 stops

ISP10:37 amIslip Long Island

$987

Find similar

Frontier

Oct 9

ISP9:37 pmIslip Long Island

21h 55m

2 stops

TYS7:32 pmKnoxville McGhee Tyson

Oct 12

TYS8:17 pmKnoxville McGhee Tyson

14h 20m

2 stops

ISP10:37 amIslip Long Island

$1,529

Find similar

Fly from

Fly to

Route

Depart

Return

Price

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Mon 9/15

5:05 pm-10:35 am

1 stop17h 30m

Knoxville McGhee Tyson

Mon 9/22

6:34 pm-10:40 am

1 stop16h 06m

$231

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Mon 9/15

5:05 pm-10:35 am

1 stop17h 30m

Knoxville McGhee Tyson

Mon 9/22

1:22 pm-10:40 am

1 stop21h 18m

$236

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Mon 9/15

5:05 pm-3:41 pm

2 stops46h 36m

Knoxville McGhee Tyson

Mon 9/22

6:34 pm-10:40 am

1 stop16h 06m

$271

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Mon 9/15

5:05 pm-3:41 pm

2 stops46h 36m

Knoxville McGhee Tyson

Mon 9/22

1:22 pm-10:40 am

1 stop21h 18m

$276

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Thu 10/30

6:37 pm-12:18 pm

1 stop17h 41m

Knoxville McGhee Tyson

Mon 11/3

7:17 pm-5:42 pm

2 stops22h 25m

$293

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Mon 10/27

4:58 pm-3:06 pm

1 stop22h 08m

Knoxville McGhee Tyson

Mon 11/3

5:59 pm-5:42 pm

1 stop23h 43m

$309

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Thu 9/4

11:45 am-11:08 pm

2 stops11h 23m

Knoxville McGhee Tyson

Mon 9/8

1:22 pm-10:40 am

1 stop21h 18m

$313

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Mon 10/27

4:58 pm-3:06 pm

1 stop22h 08m

Knoxville McGhee Tyson

Mon 11/3

7:17 pm-10:37 am

2 stops39h 20m

$340

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Thu 10/23

9:37 pm-7:32 pm

2 stops21h 55m

Knoxville McGhee Tyson

Sun 10/26

8:17 pm-10:37 am

2 stops14h 20m

$617

IslipKnoxville

ISP - TYS

ISPTYS

Islip Long Island

Thu 10/16

9:37 pm-7:32 pm

2 stops21h 55m

Knoxville McGhee Tyson

Sun 10/19

8:17 pm-10:37 am

2 stops14h 20m

$987

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Islip to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Islip to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $251. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Islip to Knoxville for around $408.

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Islip to Knoxville when you can find flight prices for as low as $265. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $359.

When to book flights from Islip to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Islip to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Islip to Knoxville (ISP to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip to Knoxville

Direct flights	None

There are no direct flights from Islip to Knoxville. There are no popular flight routes from Islip to Knoxville.

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How far is Islip Long Island to Knoxville McGhee Tyson by plane?
A flight from Islip Long Island to Knoxville McGhee Tyson will travel around 666.2 mi. In terms of flight time, this usually takes a little over 6h 59m.
When did momondo last update prices for flights from Islip Long Island Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Islip Long Island Airport to Knoxville McGhee Tyson Airport were last updated today.
How old do you have to be to fly from Islip Long Island Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

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Why use momondo?

Why should I use momondo to find a flight deal from Islip to Knoxville?

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Can I find flights from Islip to Knoxville with flexible booking policies on momondo?

All flight searches from Islip to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Islip to Knoxville?

momondo helps you find the best flight between Islip and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Islip to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Islip to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.