What airlines fly to Florida Keys?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Florida Keys from Iowa according to our data. American Airlines is the first choice among our users, with 72% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How long is the flight from Iowa to Florida Keys?

On average, it takes 12h 25m to fly from Iowa to Florida Keys if you fly out of Des Moines (the most popular airport in Iowa) and into Copenhagen (the most popular airport in Florida Keys). If you’re flying out of Cedar Rapids and into Copenhagen, then the flight time is around 21h 30m.

What is the cheapest airline that flies from Iowa to Florida Keys?

Frontier, American Airlines, and Allegiant Air are the most popular carriers operating from Iowa to Florida Keys

When did momondo last update prices for flights from Iowa to Florida Keys?

Prices for flights from Iowa to Florida Keys are updated daily.

How many operators does momondo search for flights from Iowa to Florida Keys?

As of September 2026, there are 5 operators available to choose from for flights from Iowa to Florida Keys.

How old do you have to be to fly from Iowa to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$118 Cheap Flights from Iowa to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Iowa to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:30 pm - 12:46 amDSM Des Moines-MIA Miami

27h 16m1 stop Denver Intl

5:50 am - 7:30 pmMIA Miami-DSM Des Moines

14h 40m1 stop Denver Intl

$245Frontier

Fri, Oct 2 - Mon, Oct 12

11:29 am - 12:46 amDSM Des Moines-MIA Miami

12h 17m1 stop Denver Intl

5:55 am - 10:44 amMIA Miami-DSM Des Moines

29h 49m1 stop Denver Intl

$275Frontier

Sun, Sep 27 - Sat, Oct 3

11:22 am - 7:36 pmDSM Des Moines-MIA Miami

7h 14m1 stop Charlotte Douglas

8:01 pm - 10:47 pmMIA Miami-DSM Des Moines

3h 46mnonstop

$284American Airlines

Wed, Oct 28 - Tue, Nov 3

4:12 pm - 11:14 pmDSM Des Moines-MIA Miami

6h 02m1 stop Dallas/Fort Worth

8:55 pm - 11:36 pmMIA Miami-DSM Des Moines

3h 41mnonstop

$284American Airlines

Sat, Oct 10 - Sat, Oct 17

1:25 pm - 8:05 pmOMA Omaha Eppley Airfield-MIA Miami

5h 40m1 stop Nashville Intl

6:20 am - 10:55 amMIA Miami-OMA Omaha Eppley Airfield

5h 35m1 stop Dallas Love Field

$294Southwest

Tue, Dec 8 - Sat, Dec 12

7:15 am - 4:50 pmOMA Omaha Eppley Airfield-MIA Miami

8h 35m1 stop Denver Intl

6:20 am - 10:55 amMIA Miami-OMA Omaha Eppley Airfield

5h 35m1 stop Dallas Love Field

$294Southwest

Tue, Dec 8 - Sat, Dec 12

11:35 am - 8:02 pmDSM Des Moines-EYW Key West

7h 27m1 stop Atlanta Hartsfield-Jackson

6:06 pm - 10:38 pmEYW Key West-DSM Des Moines

5h 32m1 stop Atlanta Hartsfield-Jackson

$299Delta

Sat, Dec 5 - Wed, Dec 9

8:20 am - 2:55 pmMLI Moline Quad-City-MIA Miami

5h 35m1 stop Chicago O'Hare Intl

2:10 pm - 9:03 pmMIA Miami-MLI Moline Quad-City

7h 53m1 stop Chicago O'Hare Intl

$303United Airlines

Wed, Mar 3 - Wed, Mar 10

6:45 am - 5:35 pmMLI Moline Quad-City-MIA Miami

9h 50m2 stops Chicago O'Hare Intl Newark

9:00 am - 1:40 pmMIA Miami-MLI Moline Quad-City

5h 40m1 stop Chicago O'Hare Intl

$308United Airlines

Wed, Mar 3 - Wed, Mar 10

11:35 am - 8:02 pmDSM Des Moines-EYW Key West

7h 27m1 stop Atlanta Hartsfield-Jackson

6:06 pm - 10:38 pmEYW Key West-DSM Des Moines

5h 32m1 stop Atlanta Hartsfield-Jackson

$319Delta

Sat, Dec 5 - Wed, Dec 9

Cheap last minute flights

Enter your travel dates to find the best prices.

7:29 pm - 12:46 amOMA Omaha Eppley Airfield-MIA Miami

28h 17m1 stop Denver Intl

5:50 am - 6:34 pmMIA Miami-OMA Omaha Eppley Airfield

13h 44m1 stop Denver Intl

$326Frontier

Mon, Sep 14 - Wed, Sep 30

8:30 pm - 12:46 amDSM Des Moines-MIA Miami

27h 16m1 stop Denver Intl

5:50 am - 7:33 pmMIA Miami-DSM Des Moines

14h 43m1 stop Denver Intl

$345Frontier

Mon, Sep 14 - Mon, Sep 21

5:40 am - 1:05 pmCID Cedar Rapids-MIA Miami

6h 25m1 stop Atlanta Hartsfield-Jackson

6:40 am - 11:22 amMIA Miami-CID Cedar Rapids

5h 42m1 stop Minneapolis St Paul

$422Delta

Sat, Sep 12 - Sat, Sep 19

5:40 am - 1:05 pmCID Cedar Rapids-MIA Miami

6h 25m1 stop Atlanta Hartsfield-Jackson

6:40 am - 11:22 amMIA Miami-CID Cedar Rapids

5h 42m1 stop Minneapolis St Paul

$422Delta

Sat, Sep 12 - Tue, Sep 22

3:53 pm - 11:59 pmMLI Moline Quad-City-MIA Miami

7h 06m1 stop Charlotte Douglas

9:59 am - 3:28 pmMIA Miami-MLI Moline Quad-City

6h 29m1 stop Charlotte Douglas

$436American Airlines

Sat, Sep 12 - Fri, Sep 18

12:26 pm - 8:53 pmLSE La Crosse-MIA Miami

7h 27m1 stop Chicago O'Hare Intl

5:15 am - 11:22 amMIA Miami-LSE La Crosse

7h 07m1 stop Chicago O'Hare Intl

$446American Airlines

Sat, Sep 12 - Tue, Sep 15

7:55 am - 2:51 pmCID Cedar Rapids-MIA Miami

5h 56m1 stop Chicago O'Hare Intl

7:00 am - 5:45 pmMIA Miami-CID Cedar Rapids

11h 45m2 stops Newark Chicago O'Hare Intl

$458United Airlines

Fri, Sep 11 - Sat, Sep 19

8:13 am - 2:51 pmMLI Moline Quad-City-MIA Miami

5h 38m1 stop Chicago O'Hare Intl

11:30 am - 10:35 pmMIA Miami-MLI Moline Quad-City

12h 05m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$461United Airlines

Sat, Sep 12 - Fri, Sep 18

4:55 pm - 9:24 amDSM Des Moines-EYW Key West

15h 29m1 stop Tampa St. Petersburg

10:59 am - 9:34 amEYW Key West-DSM Des Moines

23h 35m1 stop Orlando

$472Multiple Airlines

Fri, Sep 11 - Sun, Sep 13

9:27 pm - 8:38 pmOMA Omaha Eppley Airfield-MIA Miami

22h 11m2 stops Las Vegas Harry Reid Intl Atlanta Hartsfield-Jackson

5:50 am - 5:33 pmMIA Miami-OMA Omaha Eppley Airfield

12h 43m1 stop Denver Intl

$676Multiple Airlines

Mon, Sep 14 - Fri, Sep 18

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American Airlines flights from Iowa to Florida Keys

Our best American Airlines deals on Iowa to Florida Keys flight tickets

American Airlines

Oct 10

DSM4:12 pmDes Moines

6h 02m

1 stop

MIA11:14 pmMiami

Oct 17

MIA8:55 pmMiami

3h 41m

DSM11:36 pmDes Moines

$284

American Airlines

Oct 27

DSM7:00 amDes Moines

5h 35m

1 stop

EYW1:35 pmKey West

Oct 31

EYW5:28 pmKey West

7h 22m

1 stop

DSM11:50 pmDes Moines

$299

American Airlines

Oct 10

MLI4:19 pmMoline Quad-City

7h 33m

1 stop

MIA12:52 amMiami

Oct 17

MIA5:15 amMiami

6h 36m

1 stop

MLI10:51 amMoline Quad-City

$303

Frontier flights from Iowa to Florida Keys

Our best Frontier deals on Iowa to Florida Keys flight tickets

Frontier

Oct 2

DSM8:30 pmDes Moines

27h 16m

1 stop

MIA12:46 amMiami

Oct 12

MIA5:50 amMiami

14h 40m

1 stop

DSM7:30 pmDes Moines

$245

Frontier

Sep 27

DSM11:29 amDes Moines

12h 17m

1 stop

MIA12:46 amMiami

Oct 3

MIA5:55 amMiami

29h 49m

1 stop

DSM10:44 amDes Moines

$275

Frontier

Nov 13

OMA8:59 pmOmaha Eppley Airfield

26h 45m

1 stop

MIA12:44 amMiami

Nov 16

MIA5:50 amMiami

15h 21m

1 stop

OMA8:11 pmOmaha Eppley Airfield

$278

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMiami

DSM Des Moines - MIA Miami

DSMMIA

Des Moines

Fri 10/2

8:30 pm-12:46 am

1 stop27h 16m

Miami

Mon 10/12

5:50 am-7:30 pm

1 stop14h 40m

$245

Des MoinesMiami

DSM Des Moines - MIA Miami

DSMMIA

Des Moines

Sun 9/27

11:29 am-12:46 am

1 stop12h 17m

Miami

Sat 10/3

5:55 am-10:44 am

1 stop29h 49m

$275

Des MoinesMiami

DSM Des Moines - MIA Miami

DSMMIA

Des Moines

Wed 10/28

11:22 am-7:36 pm

1 stop7h 14m

Miami

Tue 11/3

8:01 pm-10:47 pm

Nonstop3h 46m

$284

Quickest round-trip

Des MoinesMiami

DSM Des Moines - MIA Miami

DSMMIA

Des Moines

Sat 10/10

4:12 pm-11:14 pm

1 stop6h 02m

Miami

Sat 10/17

8:55 pm-11:36 pm

Nonstop3h 41m

$284

OmahaMiami

OMA Omaha Eppley Airfield - MIA Miami

OMAMIA

Omaha Eppley Airfield

Tue 12/8

1:25 pm-8:05 pm

1 stop5h 40m

Miami

Sat 12/12

6:20 am-10:55 am

1 stop5h 35m

$294

OmahaMiami

OMA Omaha Eppley Airfield - MIA Miami

OMAMIA

Omaha Eppley Airfield

Tue 12/8

7:15 am-4:50 pm

1 stop8h 35m

Miami

Sat 12/12

6:20 am-10:55 am

1 stop5h 35m

$294

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

11:35 am-8:02 pm

1 stop7h 27m

Key West

Wed 12/9

6:06 pm-10:38 pm

1 stop5h 32m

$299

MolineMiami

MLI Moline Quad-City - MIA Miami

MLIMIA

Moline Quad-City

Wed 3/3

8:20 am-2:55 pm

1 stop5h 35m

Miami

Wed 3/10

2:10 pm-9:03 pm

1 stop7h 53m

$303

MolineMiami

MLI Moline Quad-City - MIA Miami

MLIMIA

Moline Quad-City

Wed 3/3

6:45 am-5:35 pm

2 stops9h 50m

Miami

Wed 3/10

9:00 am-1:40 pm

1 stop5h 40m

$308

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

11:35 am-8:02 pm

1 stop7h 27m

Key West

Wed 12/9

6:06 pm-10:38 pm

1 stop5h 32m

$319

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Iowa averaging around $399.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Iowa to Florida Keys is on a Thursday when prices can be found for as low as $628. The most expensive day to fly to Florida Keys is Friday, with ticket prices averaging around $719.

How far in advance should I book a flight from Iowa to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $423 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Iowa for as low as $321 on momondo.

Can stopping save me money on Iowa to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Iowa to Florida Keys.

Cheap Iowa to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Florida Keys

Best Price Found	$118
Fastest flight time	3h 13m
Direct flights	Every day
Airports in Florida Keys	3 airports

The best one-way flight to Florida Keys from Iowa in the past 72 hours is $118. The best round-trip flight deal from Iowa to Florida Keys found on momondo in the last 72 hours is $245.

The fastest flight from Iowa to Florida Keys takes 3h 13m

Direct flights go from Iowa to Florida Keys every day.

There are 3 airports in Florida Keys. From Iowa there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from Iowa to Florida Keys

When did momondo last update prices for flights from Iowa to Florida Keys?
Prices for flights from Iowa to Florida Keys are updated daily.
How many operators does momondo search for flights from Iowa to Florida Keys?
As of September 2026, there are 5 operators available to choose from for flights from Iowa to Florida Keys.
How old do you have to be to fly from Iowa to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Iowa to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Iowa to Florida Keys is Airbus A320-100/200, representing 17.54% of all bookings. The subsequent popular models are Airbus A319 at 13.54%, Embraer 175 (Enhanced Winglets) at 11.44%, and Embraer 175 at 11.21%.

Best airlines flying from Iowa to Florida Keys

Compare and see reviews for airlines that fly from Iowa to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $230	Free Cancellation	Rating 7.4 10,190 reviews	Search United Airlines flights
Delta	PriceFrom $268	Free Cancellation	Rating 7.8 8,554 reviews	Search Delta flights
American Airlines	PriceFrom $289	Free Cancellation	Rating 7.1 12,045 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Florida Keys?

It is quick and easy to find Iowa to Florida Keys flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florida Keys that suits you.

Can I find flights from Iowa to Florida Keys with flexible booking policies on momondo?

Flights from Iowa to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Iowa to Florida Keys?

Once all potential Iowa to Florida Keys flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Florida Keys right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Iowa to Florida Keys now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florida Keys and let you know when they change.