Cheap flights from Iowa to Florence from $447

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Florence departing on 8/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

American Airlines Logo
7:04 am - 2:09 pmMLI-FLO
6h 05m1 stop
American Airlines Logo
5:37 pm - 10:25 pmFLO-MLI
5h 48m1 stop
$447American Airlines
Find Deal
Sat, Aug 30 - Wed, Sep 3
American Airlines Logo
6:04 am - 2:09 pmMLI-FLO
7h 05m2 stops
American Airlines Logo
5:37 pm - 10:25 pmFLO-MLI
5h 48m1 stop
$452American Airlines
Find Deal
Sat, Aug 30 - Wed, Sep 3
American Airlines Logo
6:04 am - 2:09 pmMLI-FLO
7h 05m2 stops
American Airlines Logo
6:14 am - 5:10 pmFLO-MLI
11h 56m2 stops
$493American Airlines
Find Deal
Sat, Aug 30 - Wed, Sep 3
American Airlines Logo
7:06 am - 2:08 pmCID-FLO
6h 02m1 stop
American Airlines Logo
2:29 pm - 9:36 pmFLO-CID
8h 07m2 stops
$496American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
5:00 am - 2:08 pmCID-FLO
8h 08m2 stops
American Airlines Logo
11:14 am - 5:45 pmFLO-CID
7h 31m2 stops
$501American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
6:20 am - 5:25 pmMLI-FLO
10h 05m2 stops
American Airlines Logo
5:37 pm - 10:25 pmFLO-MLI
5h 48m1 stop
$508American Airlines
Find Deal
Sat, Aug 30 - Wed, Sep 3
American Airlines Logo
6:20 am - 5:25 pmMLI-FLO
10h 05m2 stops
American Airlines Logo
6:14 am - 5:10 pmFLO-MLI
11h 56m2 stops
$513American Airlines
Find Deal
Sat, Aug 30 - Wed, Sep 3
American Airlines Logo
2:51 pm - 11:40 pmALO-FLO
7h 49m2 stops
American Airlines Logo
6:55 am - 2:20 pmFLO-ALO
8h 25m2 stops
$571American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
6:20 am - 5:25 pmMLI-FLO
10h 05m2 stops
American Airlines Logo
6:14 am - 5:10 pmFLO-MLI
11h 56m2 stops
$638American Airlines
Find Deal
Sat, Aug 30 - Wed, Sep 3
American Airlines Logo
7:06 am - 2:08 pmCID-FLO
6h 02m1 stop
American Airlines Logo
2:29 pm - 9:38 pmFLO-CID
8h 09m1 stop
$819American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13

American Airlines flights from Iowa to Florence, South Carolina

Our best American Airlines deals on Iowa to Florence, South Carolina flight tickets
American Airlines
Aug 30
MLI7:04 amMoline Quad-City
6h 05m
1 stop
FLO2:09 pmFlorence
Sep 3
FLO5:37 pmFlorence
5h 48m
1 stop
MLI10:25 pmMoline Quad-City
American Airlines
Aug 30
MLI7:04 amMoline Quad-City
6h 05m
1 stop
FLO2:09 pmFlorence
Sep 3
FLO6:14 amFlorence
11h 56m
2 stops
MLI5:10 pmMoline Quad-City
American Airlines
Aug 30
MLI6:04 amMoline Quad-City
7h 05m
2 stops
FLO2:09 pmFlorence
Sep 3
FLO6:14 amFlorence
11h 56m
2 stops
MLI5:10 pmMoline Quad-City

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Iowa to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 8/30

7:04 am-2:09 pm

1 stop6h 05m

Florence

Wed 9/3

5:37 pm-10:25 pm

1 stop5h 48m

$447

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 8/30

6:04 am-2:09 pm

2 stops7h 05m

Florence

Wed 9/3

5:37 pm-10:25 pm

1 stop5h 48m

$452

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 8/30

6:04 am-2:09 pm

2 stops7h 05m

Florence

Wed 9/3

6:14 am-5:10 pm

2 stops11h 56m

$493

Cedar RapidsFlorence

CID - FLO

CIDFLO

Cedar Rapids

Wed 12/10

7:06 am-2:08 pm

1 stop6h 02m

Florence

Sat 12/13

2:29 pm-9:36 pm

2 stops8h 07m

$496

Cedar RapidsFlorence

CID - FLO

CIDFLO

Cedar Rapids

Wed 12/10

5:00 am-2:08 pm

2 stops8h 08m

Florence

Sat 12/13

11:14 am-5:45 pm

2 stops7h 31m

$501

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 8/30

6:20 am-5:25 pm

2 stops10h 05m

Florence

Wed 9/3

5:37 pm-10:25 pm

1 stop5h 48m

$508

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 8/30

6:20 am-5:25 pm

2 stops10h 05m

Florence

Wed 9/3

6:14 am-5:10 pm

2 stops11h 56m

$513

WaterlooFlorence

ALO - FLO

ALOFLO

Waterloo

Wed 12/10

2:51 pm-11:40 pm

2 stops7h 49m

Florence

Sat 12/13

6:55 am-2:20 pm

2 stops8h 25m

$571

MolineFlorence

MLI - FLO

MLIFLO

Moline Quad-City

Sat 8/30

6:20 am-5:25 pm

2 stops10h 05m

Florence

Wed 9/3

6:14 am-5:10 pm

2 stops11h 56m

$638

Cedar RapidsFlorence

CID - FLO

CIDFLO

Cedar Rapids

Wed 12/10

7:06 am-2:08 pm

1 stop6h 02m

Florence

Sat 12/13

2:29 pm-9:38 pm

1 stop8h 09m

$819

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Iowa to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Florence, South Carolina from Iowa according to our data. American Airlines is the first choice among our users, with 77% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 4 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Iowa to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Florence, South Carolina

Direct flights

None
There are no direct flights from Iowa to Florence, South Carolina. There are no popular flight routes from Iowa to Florence, South Carolina.
  • When did momondo last update prices for flights from Iowa to Florence Airport?

    Prices for flights from Iowa to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Iowa to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Iowa to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Iowa to Florence with flexible booking policies on momondo?

All flight searches from Iowa to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to Florence?

Once all potential Iowa to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Iowa to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Mon 8/25
Mon 9/1

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