What is the cheapest airline that flies from Indianapolis to South Carolina?

Allegiant Air, Spirit Airlines, and United Airlines are the most popular carriers operating from Indianapolis to South Carolina

How many flights depart from Indianapolis to South Carolina on average per week?

The number of flights available between Indianapolis and South Carolina is 36 per week as of April 2026. The most frequent departure day is Mon, with 19% of weekly flights leaving on this day.

What airlines fly to South Carolina?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to South Carolina from Indianapolis according to our data. Allegiant Air is the first choice among our users, with 44% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Indianapolis Airport to South Carolina?

Prices for flights from Indianapolis Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Indianapolis Airport to South Carolina?

The number of operators available for flights from Indianapolis Airport to South Carolina is 8 as of April 2026.

How old do you have to be to fly from Indianapolis Airport to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$44 Cheap Flights from Indianapolis to South Carolina in 2026

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Find the cheapest flights from Indianapolis to South Carolina

Round-trip

One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

11:11 am - 12:55 pm

IND

SAV

1h 44mnonstop

8:30 am - 10:21 am

SAV

IND

1h 51mnonstop

$67Allegiant Air

Δευ, Απρ 27 - Παρ, Μαϊ 1

11:11 am - 12:55 pm

IND

SAV

1h 44mnonstop

8:30 am - 10:21 am

SAV

IND

1h 51mnonstop

$76Allegiant Air

Δευ, Απρ 27 - Παρ, Μαϊ 1

5:30 am - 2:36 pm

IND

CLT

9h 06m

1 stop

2:59 pm - 11:59 pm

CLT

IND

9h 00m

1 stop

$151Spirit Airlines

Πεμ, Απρ 30 - Σαβ, Μαϊ 2

5:30 am - 2:36 pm

IND

CLT

9h 06m

1 stop

9:04 am - 11:21 am

CLT

IND

26h 17m

1 stop

$162Spirit Airlines

Πεμ, Απρ 30 - Κυρ, Μαϊ 3

2:48 pm - 11:10 pm

IND

CAE

8h 22m

1 stop

1:47 pm - 7:22 pm

CAE

IND

5h 35m

1 stop

$231Delta

Τετ, Ιουν 10 - Σαβ, Ιουν 13

6:38 pm - 11:45 pm

IND

CAE

5h 07m

1 stop

6:00 am - 10:34 am

CAE

IND

4h 34m

1 stop

$251Delta

Σαβ, Ιουν 27 - Σαβ, Ιουλ 4

6:20 am - 2:40 pm

IND

CAE

8h 20m

1 stop

8:30 pm - 12:08 am

CAE

IND

3h 38m

1 stop

$265American Airlines

Τετ, Ιουν 10 - Σαβ, Ιουν 13

5:33 am - 12:02 pm

IND

CAE

6h 29m

1 stop

6:39 pm - 12:11 am

CAE

IND

5h 32m

1 stop

$271American Airlines

Σαβ, Ιουν 13 - Τετ, Ιουν 17

7:05 am - 12:52 pm

IND

HHH

5h 47m

1 stop

3:00 pm - 10:07 pm

HHH

IND

7h 07m

1 stop

$326United Airlines

Δευ, Σεπ 7 - Σαβ, Σεπ 12

9:20 am - 2:21 pm

IND

HHH

5h 01m

1 stop

1:45 pm - 10:15 pm

HHH

IND

8h 30m

1 stop

$336United Airlines

Πεμ, Ιουλ 2 - Τρι, Ιουλ 7

Frontier flights from Indianapolis to South Carolina

Our best Frontier deals on Indianapolis to South Carolina flight tickets

Frontier

Apr 30

IND8:46 pmIndianapolis

20h 49m

1 stop

CLT5:35 pmCharlotte Douglas

May 2

CLT5:51 pmCharlotte Douglas

26h 05m

1 stop

IND7:56 pmIndianapolis

$140

Frontier

Apr 27

IND7:14 pmIndianapolis

21h 21m

1 stop

CLT4:35 pmCharlotte Douglas

Apr 29

CLT8:09 pmCharlotte Douglas

11h 34m

1 stop

IND7:43 amIndianapolis

$153

Frontier

May 1

IND8:46 pmIndianapolis

20h 10m

1 stop

CLT4:56 pmCharlotte Douglas

May 3

CLT8:50 amCharlotte Douglas

26h 59m

1 stop

IND11:49 amIndianapolis

$160

Spirit Airlines flights from Indianapolis to South Carolina

Our best Spirit Airlines deals on Indianapolis to South Carolina flight tickets

Spirit Airlines

May 6

IND12:26 pmIndianapolis

11h 14m

1 stop

CLT11:40 pmCharlotte Douglas

May 8

CLT9:07 pmCharlotte Douglas

14h 14m

1 stop

IND11:21 amIndianapolis

$163

Spirit Airlines

May 1

IND5:30 amIndianapolis

9h 06m

1 stop

CLT2:36 pmCharlotte Douglas

May 4

CLT9:07 pmCharlotte Douglas

14h 14m

1 stop

IND11:21 amIndianapolis

$166

Spirit Airlines

Apr 27

IND12:07 pmIndianapolis

8h 30m

1 stop

CLT8:37 pmCharlotte Douglas

May 4

CLT9:07 pmCharlotte Douglas

14h 14m

1 stop

IND11:21 amIndianapolis

$173

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to South Carolina that are best for you.

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Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

IndianapolisSavannah

IND - SAV

INDSAV

Indianapolis

Δευ 4/27

11:11 am-12:55 pm

Nonstop1h 44m

Savannah/Hilton Head

Παρ 5/1

8:30 am-10:21 am

Nonstop1h 51m

$67

IndianapolisSavannah

IND - SAV

INDSAV

Indianapolis

Δευ 4/27

11:11 am-12:55 pm

Nonstop1h 44m

Savannah/Hilton Head

Παρ 5/1

8:30 am-10:21 am

Nonstop1h 51m

$76

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Πεμ 4/30

5:30 am-2:36 pm

1 stop9h 06m

Charlotte Douglas

Σαβ 5/2

2:59 pm-11:59 pm

1 stop9h 00m

$151

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Πεμ 4/30

5:30 am-2:36 pm

1 stop9h 06m

Charlotte Douglas

Κυρ 5/3

9:04 am-11:21 am

1 stop26h 17m

$162

IndianapolisColumbia

IND - CAE

INDCAE

Indianapolis

Τετ 6/10

2:48 pm-11:10 pm

1 stop8h 22m

Columbia Metropolitan

Σαβ 6/13

1:47 pm-7:22 pm

1 stop5h 35m

$231

IndianapolisColumbia

IND - CAE

INDCAE

Indianapolis

Σαβ 6/27

6:38 pm-11:45 pm

1 stop5h 07m

Columbia Metropolitan

Σαβ 7/4

6:00 am-10:34 am

1 stop4h 34m

$251

IndianapolisColumbia

IND - CAE

INDCAE

Indianapolis

Τετ 6/10

6:20 am-2:40 pm

1 stop8h 20m

Columbia Metropolitan

Σαβ 6/13

8:30 pm-12:08 am

1 stop3h 38m

$265

IndianapolisColumbia

IND - CAE

INDCAE

Indianapolis

Σαβ 6/13

5:33 am-12:02 pm

1 stop6h 29m

Columbia Metropolitan

Τετ 6/17

6:39 pm-12:11 am

1 stop5h 32m

$271

IndianapolisHilton Head Island

IND - HHH

INDHHH

Indianapolis

Δευ 9/7

7:05 am-12:52 pm

1 stop5h 47m

Hilton Head Island

Σαβ 9/12

3:00 pm-10:07 pm

1 stop7h 07m

$326

IndianapolisHilton Head Island

IND - HHH

INDHHH

Indianapolis

Πεμ 7/2

9:20 am-2:21 pm

1 stop5h 01m

Hilton Head Island

Τρι 7/7

1:45 pm-10:15 pm

1 stop8h 30m

$336

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indianapolis to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Indianapolis is in June. Flight prices, which tend to average around $161, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to South Carolina from Indianapolis during July instead. Flights to South Carolina in July, while not as cheap as those in June, still average around $215.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $45. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $149.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Indianapolis to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $135. Try not to purchase tickets in the afternoon because they tend to be around $143. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Indianapolis to South Carolina flight route?

Fly from Indianapolis to Charleston for the best Indianapolis - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $323 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Indianapolis for as low as $193 on momondo.

What cabin class options are available on Indianapolis to South Carolina flights?

There is only 1 cabin class available to choose from on Indianapolis to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indianapolis to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Indianapolis to South Carolina.

Cheap Indianapolis to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to South Carolina

Best Price Found	$46
Fastest flight time	1h 42m
Direct flights	Every day
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Indianapolis in the past 72 hours is $46. The best round-trip flight deal from Indianapolis to South Carolina found on momondo in the last 72 hours is $104.

The fastest flight from Indianapolis to South Carolina takes 1h 42m

Direct flights go from Indianapolis to South Carolina every day.

There are 57 airports in South Carolina. From Indianapolis there are direct flights to Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Indianapolis to South Carolina

When did momondo last update prices for flights from Indianapolis Airport to South Carolina?
Prices for flights from Indianapolis Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Indianapolis Airport to South Carolina?
The number of operators available for flights from Indianapolis Airport to South Carolina is 8 as of April 2026.
How old do you have to be to fly from Indianapolis Airport to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Indianapolis to South Carolina?
momondo data reveals that the most frequently booked plane model on the route from Indianapolis to South Carolina is Airbus A320-100/200, representing 89.66% of all bookings. The subsequent popular models are Airbus A319 at 3.45%, Boeing 737 MAX 8 at 1.72%, and Embraer 175 (Enhanced Winglets) at 1.72%.

Best airlines flying from Indianapolis to South Carolina

Compare and see reviews for airlines that fly from Indianapolis to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $61	Free Cancellation	Rating 7.3 707 reviews	Search Allegiant Air flights
Spirit Airlines	PriceFrom $95	Free Cancellation	Rating 6.3 8,617 reviews	Search Spirit Airlines flights
Delta	PriceFrom $183	Free Cancellation	Rating 7.9 8,407 reviews	Search Delta flights
American Airlines	PriceFrom $196	Free Cancellation	Rating 7.1 11,568 reviews	Search American Airlines flights
Southwest	PriceFrom $247	Free Cancellation	Rating 8.0 4,328 reviews	Search Southwest flights
United Airlines	PriceFrom $266	Free Cancellation	Rating 7.4 9,581 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Indianapolis to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Indianapolis to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to South Carolina?

momondo helps you find the best flight between Indianapolis and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Indianapolis to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

An easier way to manage your South Carolina trip

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Popular cities in South Carolina

Flights to New Yorkfrom $55

Flights to Los Angelesfrom $48

Flights to Orlandofrom $49

Flights to Miamifrom $56

Flights to Chicagofrom $60

Flights to San Franciscofrom $56

Flights to Las Vegasfrom $48

Flights to Washington, D.C.from $56

Flights to Bostonfrom $66

Flights to Atlantafrom $51

Flights to Dallasfrom $59

Flights to Fort Lauderdalefrom $53

Cheap flights from Indianapolis to South Carolina from $44

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to South Carolina departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from Indianapolis to South Carolina

Our best Frontier deals on Indianapolis to South Carolina flight tickets

Spirit Airlines flights from Indianapolis to South Carolina

Our best Spirit Airlines deals on Indianapolis to South Carolina flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Indianapolis to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Indianapolis to South Carolina flight route?

How far in advance should I book a flight to South Carolina?

What cabin class options are available on Indianapolis to South Carolina flights?

Can stopping save me money on Indianapolis to South Carolina flights?

What is the cheapest airline that flies from Indianapolis to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Indianapolis to South Carolina on average per week?

Cheap Indianapolis to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Frequently asked questions about flying from Indianapolis to South Carolina

Best airlines flying from Indianapolis to South Carolina

Compare and see reviews for airlines that fly from Indianapolis to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

Indianapolis flight routes

According to popular flight searches on momondo this year

South Carolina flight routes

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