What is the cheapest airline that flies from Indianapolis to South Carolina?

Allegiant Air, Spirit Airlines, and Frontier are the most popular carriers operating from Indianapolis to South Carolina

How many flights depart from Indianapolis to South Carolina on average per week?

The number of flights available between Indianapolis and South Carolina is 36 per week as of February 2026. The most frequent departure day is Mon, with 17% of weekly flights leaving on this day.

What airlines fly to South Carolina?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to South Carolina from Indianapolis according to our data. Allegiant Air is the first choice among our users, with 42% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Indianapolis Airport to South Carolina?

Prices for flights from Indianapolis Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Indianapolis Airport to South Carolina?

The number of operators available for flights from Indianapolis Airport to South Carolina is 7 as of February 2026.

How old do you have to be to fly from Indianapolis Airport to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$51 Cheap Flights from Indianapolis to South Carolina in 2026

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Find the cheapest flights from Indianapolis to South Carolina

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

11:11 am - 12:55 pm

IND

SAV

1h 44mnonstop

8:30 am - 10:21 am

SAV

IND

1h 51mnonstop

$86Allegiant Air

Mon, May 4 - Fri, May 8

4:15 pm - 6:04 pm

IND

CHS

1h 49mnonstop

9:25 pm - 11:21 pm

CHS

IND

1h 56mnonstop

$95Allegiant Air

Mon, Jun 1 - Fri, Jun 5

6:00 am - 2:31 pm

IND

CHS

8h 31m

1 stop

3:26 pm - 12:08 am

CHS

IND

8h 42m

1 stop

$136Spirit Airlines

Sat, May 2 - Sat, May 9

6:00 am - 2:31 pm

IND

CHS

8h 31m

1 stop

3:26 pm - 12:08 am

CHS

IND

8h 42m

1 stop

$137Spirit Airlines

Sat, May 2 - Sat, May 9

7:15 pm - 11:55 pm

IND

CAE

4h 40m

1 stop

8:12 pm - 12:09 am

CAE

IND

3h 57m

1 stop

$192American Airlines

Sat, Apr 18 - Sat, Apr 25

7:05 am - 11:24 am

IND

GSP

4h 19m

1 stop

6:51 am - 10:24 am

GSP

IND

3h 33m

1 stop

$249Delta

Sat, May 2 - Wed, May 6

6:00 am - 12:28 pm

IND

CAE

6h 28m

1 stop

6:50 pm - 11:15 pm

CAE

IND

4h 25m

1 stop

$249Delta

Fri, Jun 12 - Mon, Jun 15

6:25 am - 12:00 pm

IND

GSP

5h 35m

1 stop

6:45 am - 12:40 pm

GSP

IND

5h 55m

1 stop

$254Southwest

Mon, May 4 - Wed, May 6

8:00 am - 2:39 pm

IND

AGS

6h 39m

1 stop

4:31 pm - 11:59 pm

AGS

IND

7h 28m

1 stop

$257American Airlines

Wed, Mar 18 - Mon, Mar 30

6:35 pm - 10:15 pm

IND

GSP

3h 40m

1 stop

6:45 am - 2:15 pm

GSP

IND

7h 30m

2 stops

$259Southwest

Mon, May 4 - Wed, May 6

Frontier flights from Indianapolis to South Carolina

Our best Frontier deals on Indianapolis to South Carolina flight tickets

Frontier

Apr 17

IND7:18 pmIndianapolis

21h 17m

1 stop

CLT4:35 pmCharlotte Douglas

Apr 19

CLT6:18 pmCharlotte Douglas

25h 42m

1 stop

IND8:00 pmIndianapolis

$160

Frontier

Apr 23

IND8:46 pmIndianapolis

20h 49m

1 stop

CLT5:35 pmCharlotte Douglas

Apr 26

CLT8:50 amCharlotte Douglas

26h 59m

1 stop

IND11:49 amIndianapolis

$171

Frontier

Apr 13

IND5:30 pmIndianapolis

7h 06m

1 stop

CLT12:36 amCharlotte Douglas

Apr 16

CLT9:31 amCharlotte Douglas

9h 10m

1 stop

IND6:41 pmIndianapolis

$181

Spirit Airlines flights from Indianapolis to South Carolina

Our best Spirit Airlines deals on Indianapolis to South Carolina flight tickets

Spirit Airlines

May 2

IND6:00 amIndianapolis

8h 31m

1 stop

CHS2:31 pmCharleston

May 9

CHS3:26 pmCharleston

8h 42m

1 stop

IND12:08 amIndianapolis

$136

Spirit Airlines

May 2

IND6:00 amIndianapolis

8h 31m

1 stop

CHS2:31 pmCharleston

May 9

CHS3:26 pmCharleston

8h 42m

1 stop

IND12:08 amIndianapolis

$137

Spirit Airlines

Apr 12

IND6:00 amIndianapolis

5h 09m

1 stop

CHS11:09 amCharleston

Apr 16

CHS3:26 pmCharleston

8h 42m

1 stop

IND12:08 amIndianapolis

$151

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSavannah

IND - SAV

INDSAV

Indianapolis

Mon 5/4

11:11 am-12:55 pm

Nonstop1h 44m

Savannah/Hilton Head

Fri 5/8

8:30 am-10:21 am

Nonstop1h 51m

$86

IndianapolisCharleston

IND - CHS

INDCHS

Indianapolis

Mon 6/1

4:15 pm-6:04 pm

Nonstop1h 49m

Charleston

Fri 6/5

9:25 pm-11:21 pm

Nonstop1h 56m

$95

IndianapolisCharleston

IND - CHS

INDCHS

Indianapolis

Sat 5/2

6:00 am-2:31 pm

1 stop8h 31m

Charleston

Sat 5/9

3:26 pm-12:08 am

1 stop8h 42m

$136

IndianapolisCharleston

IND - CHS

INDCHS

Indianapolis

Sat 5/2

6:00 am-2:31 pm

1 stop8h 31m

Charleston

Sat 5/9

3:26 pm-12:08 am

1 stop8h 42m

$137

IndianapolisColumbia

IND - CAE

INDCAE

Indianapolis

Sat 4/18

7:15 pm-11:55 pm

1 stop4h 40m

Columbia Metropolitan

Sat 4/25

8:12 pm-12:09 am

1 stop3h 57m

$192

IndianapolisGreenville

IND - GSP

INDGSP

Indianapolis

Sat 5/2

7:05 am-11:24 am

1 stop4h 19m

Greenville

Wed 5/6

6:51 am-10:24 am

1 stop3h 33m

$249

IndianapolisColumbia

IND - CAE

INDCAE

Indianapolis

Fri 6/12

6:00 am-12:28 pm

1 stop6h 28m

Columbia Metropolitan

Mon 6/15

6:50 pm-11:15 pm

1 stop4h 25m

$249

IndianapolisGreenville

IND - GSP

INDGSP

Indianapolis

Mon 5/4

6:25 am-12:00 pm

1 stop5h 35m

Greenville

Wed 5/6

6:45 am-12:40 pm

1 stop5h 55m

$254

IndianapolisAugusta

IND - AGS

INDAGS

Indianapolis

Wed 3/18

8:00 am-2:39 pm

1 stop6h 39m

Augusta Bush Field

Mon 3/30

4:31 pm-11:59 pm

1 stop7h 28m

$257

IndianapolisGreenville

IND - GSP

INDGSP

Indianapolis

Mon 5/4

6:35 pm-10:15 pm

1 stop3h 40m

Greenville

Wed 5/6

6:45 am-2:15 pm

2 stops7h 30m

$259

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indianapolis to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Indianapolis is in June. Flight prices, which tend to average around $165, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to South Carolina from Indianapolis during July instead. Flights to South Carolina in July, while not as cheap as those in June, still average around $224.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $45. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $149.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Indianapolis to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $140. Try not to purchase tickets in the afternoon because they tend to be around $155. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Indianapolis to South Carolina flight route?

Fly from Indianapolis to Myrtle Beach Intl for the best Indianapolis - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $313 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Indianapolis for as low as $181 on momondo.

What cabin class options are available on Indianapolis to South Carolina flights?

There is only 1 cabin class available to choose from on Indianapolis to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indianapolis to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Indianapolis to South Carolina.

Cheap Indianapolis to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to South Carolina

Best Price Found	$166
Fastest flight time	1h 43m
Direct flights	Mon, Tue, Thu, Fri, Sat and Sun
Airports in South Carolina	57 airports

The best flight deal from Indianapolis to South Carolina found on momondo in the last 72 hours is $166

The fastest flight from Indianapolis to South Carolina takes 1h 43m

Direct flights go from Indianapolis to South Carolina on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Allegiant Air.

There are 57 airports in South Carolina. From Indianapolis there are direct flights to Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS).

Search flight deals

When did momondo last update prices for flights from Indianapolis Airport to South Carolina?
Prices for flights from Indianapolis Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Indianapolis Airport to South Carolina?
The number of operators available for flights from Indianapolis Airport to South Carolina is 7 as of February 2026.
How old do you have to be to fly from Indianapolis Airport to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Indianapolis to South Carolina?
momondo data reveals that the most frequently booked plane model on the route from Indianapolis to South Carolina is Airbus A320-100/200, representing 71.43% of all bookings. The subsequent popular models are Airbus A319 at 17.14%, Boeing 737 MAX 8 at 2.86%, and Embraer 175 (Enhanced Winglets) at 2.86%.

Best airlines flying from Indianapolis to South Carolina

Compare and see reviews for airlines that fly from Indianapolis to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $61	Free Cancellation	Rating 7.2 715 reviews	Search Allegiant Air flights
Spirit Airlines	PriceFrom $95	Free Cancellation	Rating 6.3 8,494 reviews	Search Spirit Airlines flights
Delta	PriceFrom $151	Free Cancellation	Rating 7.9 8,240 reviews	Search Delta flights
American Airlines	PriceFrom $196	Free Cancellation	Rating 7.1 11,366 reviews	Search American Airlines flights
United Airlines	PriceFrom $228	Free Cancellation	Rating 7.4 9,363 reviews	Search United Airlines flights
Southwest	PriceFrom $253	Free Cancellation	Rating 8.0 4,302 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Indianapolis to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Indianapolis to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to South Carolina?

momondo helps you find the best flight between Indianapolis and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indianapolis to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Indianapolis to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

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Popular cities in South Carolina

Flights to New Yorkfrom $56

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Flights to Chicagofrom $53

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Flights to Las Vegasfrom $53

Flights to Washington, D.C.from $56

Flights to Bostonfrom $75

Flights to Atlantafrom $49

Flights to Dallasfrom $54

Flights to Seattlefrom $48

Cheap flights from Indianapolis to South Carolina from $51

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to South Carolina departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from Indianapolis to South Carolina

Our best Frontier deals on Indianapolis to South Carolina flight tickets

Spirit Airlines flights from Indianapolis to South Carolina

Our best Spirit Airlines deals on Indianapolis to South Carolina flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Indianapolis to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Indianapolis to South Carolina flight route?

How far in advance should I book a flight to South Carolina?

What cabin class options are available on Indianapolis to South Carolina flights?

Can stopping save me money on Indianapolis to South Carolina flights?

What is the cheapest airline that flies from Indianapolis to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Indianapolis to South Carolina on average per week?

Cheap Indianapolis to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Best airlines flying from Indianapolis to South Carolina

Compare and see reviews for airlines that fly from Indianapolis to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

Indianapolis flight routes

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