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Cheap flights from Illinois to Florence from $207

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Illinois to Florence departing on 6/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Illinois to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:30 am - 2:56 pm
ORD
-
FLO
6h 26m
1 stop
American Airlines Logo
6:24 am - 10:47 am
FLO
-
ORD
5h 23m
1 stop
$346American Airlines
Wed, Aug 12 - Fri, Aug 21
American Airlines Logo
6:34 am - 2:56 pm
ORD
-
FLO
7h 22m
2 stops
American Airlines Logo
6:24 am - 10:47 am
FLO
-
ORD
5h 23m
1 stop
$351American Airlines
Wed, Aug 12 - Fri, Aug 21
American Airlines Logo
8:35 am - 3:40 pm
ORD
-
FLO
6h 05m
1 stop
American Airlines Logo
6:31 pm - 11:39 pm
FLO
-
ORD
6h 08m
1 stop
$379American Airlines
Fri, Sep 18 - Mon, Sep 21
American Airlines Logo
7:30 am - 2:10 pm
STL
-
FLO
5h 40m
1 stop
American Airlines Logo
5:05 am - 8:32 am
FLO
-
STL
4h 27m
1 stop
$417American Airlines
Mon, Jun 15 - Sun, Jun 21
American Airlines Logo
4:49 pm - 10:00 pm
ORD
-
FLO
4h 11m
1 stop
American Airlines Logo
2:35 pm - 5:50 pm
FLO
-
ORD
4h 15m
1 stop
$419American Airlines
Sat, Jun 6 - Sat, Jun 13
American Airlines Logo
6:15 am - 2:10 pm
STL
-
FLO
6h 55m
2 stops
American Airlines Logo
5:05 am - 8:32 am
FLO
-
STL
4h 27m
1 stop
$422American Airlines
Mon, Jun 15 - Sun, Jun 21
American Airlines Logo
6:29 am - 2:10 pm
ORD
-
FLO
6h 41m
1 stop
American Airlines Logo
5:05 am - 9:02 am
FLO
-
ORD
4h 57m
1 stop
$424American Airlines
Mon, Jun 15 - Sun, Jun 21
American Airlines Logo
5:00 am - 2:10 pm
ORD
-
FLO
8h 10m
2 stops
American Airlines Logo
5:05 am - 9:02 am
FLO
-
ORD
4h 57m
1 stop
$429American Airlines
Mon, Jun 15 - Sun, Jun 21
American Airlines Logo
4:49 pm - 10:00 pm
ORD
-
FLO
4h 11m
1 stop
American Airlines Logo
5:05 am - 9:02 am
FLO
-
ORD
4h 57m
1 stop
$435American Airlines
Mon, Jun 8 - Fri, Jun 12
American Airlines Logo
4:49 pm - 10:00 pm
ORD
-
FLO
4h 11m
1 stop
American Airlines Logo
5:05 am - 9:02 am
FLO
-
ORD
4h 57m
1 stop
$467American Airlines
Sat, Jun 6 - Fri, Jun 12

American Airlines flights from Illinois to Florence, South Carolina

Our best American Airlines deals on Illinois to Florence, South Carolina flight tickets
American Airlines
Aug 12
ORD7:30 amChicago O'Hare Intl
6h 26m
1 stop
FLO2:56 pmFlorence
Aug 21
FLO6:24 amFlorence
5h 23m
1 stop
ORD10:47 amChicago O'Hare Intl
$346
American Airlines
Aug 12
ORD6:34 amChicago O'Hare Intl
7h 22m
2 stops
FLO2:56 pmFlorence
Aug 21
FLO6:24 amFlorence
5h 23m
1 stop
ORD10:47 amChicago O'Hare Intl
$351
American Airlines
Sep 18
ORD8:35 amChicago O'Hare Intl
6h 05m
1 stop
FLO3:40 pmFlorence
Sep 21
FLO6:31 pmFlorence
6h 08m
1 stop
ORD11:39 pmChicago O'Hare Intl
$379

momondo Fare Finder

 
Customize your flight search to find flights from Illinois to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from Illinois to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Wed 8/12

7:30 am-2:56 pm

1 stop6h 26m

Florence

Fri 8/21

6:24 am-10:47 am

1 stop5h 23m

$346

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Wed 8/12

6:34 am-2:56 pm

2 stops7h 22m

Florence

Fri 8/21

6:24 am-10:47 am

1 stop5h 23m

$351

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Fri 9/18

8:35 am-3:40 pm

1 stop6h 05m

Florence

Mon 9/21

6:31 pm-11:39 pm

1 stop6h 08m

$379

St. LouisFlorence

STL - FLO

STLFLO

Lambert-St Louis

Mon 6/15

7:30 am-2:10 pm

1 stop5h 40m

Florence

Sun 6/21

5:05 am-8:32 am

1 stop4h 27m

$417
Quickest round-trip

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Sat 6/6

4:49 pm-10:00 pm

1 stop4h 11m

Florence

Sat 6/13

2:35 pm-5:50 pm

1 stop4h 15m

$419

St. LouisFlorence

STL - FLO

STLFLO

Lambert-St Louis

Mon 6/15

6:15 am-2:10 pm

2 stops6h 55m

Florence

Sun 6/21

5:05 am-8:32 am

1 stop4h 27m

$422

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Mon 6/15

6:29 am-2:10 pm

1 stop6h 41m

Florence

Sun 6/21

5:05 am-9:02 am

1 stop4h 57m

$424

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Mon 6/15

5:00 am-2:10 pm

2 stops8h 10m

Florence

Sun 6/21

5:05 am-9:02 am

1 stop4h 57m

$429

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Mon 6/8

4:49 pm-10:00 pm

1 stop4h 11m

Florence

Fri 6/12

5:05 am-9:02 am

1 stop4h 57m

$435

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Sat 6/6

4:49 pm-10:00 pm

1 stop4h 11m

Florence

Fri 6/12

5:05 am-9:02 am

1 stop4h 57m

$467

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Illinois to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Illinois to Florence?

American Airlines is the most popular carrier operating from Illinois to Florence

What airlines fly to Florence, South Carolina?

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Florence, South Carolina from Illinois according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 7 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Illinois to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Illinois to Florence, South Carolina

Fastest flight time

4h 36m

Direct flights

None
The fastest flight from Illinois to Florence, South Carolina takes 4h 36m
There are no direct flights from Illinois to Florence, South Carolina. There are no popular flight routes from Illinois to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Illinois to Florence, South Carolina

  • When did momondo last update prices for flights from Illinois to Florence Airport?

    Prices for flights from Illinois to Florence Airport are updated daily.

  • How many operators does momondo search for flights from Illinois to Florence Airport?

  • How old do you have to be to fly from Illinois to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Illinois to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Illinois to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Illinois to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Illinois to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Illinois with this policy.

How can momondo help me find flights from Illinois to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Illinois to Florence.

I’m not ready to book a flight from Illinois to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Illinois to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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