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Cheap flights from Illinois to Florence from $393

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Illinois to Florence departing on 11/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Illinois to Florence

Cheap round-trip flights

American Airlines Logo
5:00 am - 10:45 amORD-FLO
4h 45m1 stop
American Airlines Logo
5:35 pm - 11:39 pmFLO-ORD
7h 04m1 stop
$393American Airlines
Find Deal
Thu, Nov 27 - Mon, Dec 8
American Airlines Logo
5:00 am - 10:45 amORD-FLO
4h 45m1 stop
American Airlines Logo
10:28 am - 4:51 pmFLO-ORD
7h 23m2 stops
$398American Airlines
Find Deal
Thu, Nov 27 - Mon, Dec 8
American Airlines Logo
4:02 pm - 12:03 amORD-FLO
7h 01m2 stops
American Airlines Logo
10:28 am - 4:51 pmFLO-ORD
7h 23m2 stops
$454American Airlines
Find Deal
Fri, Nov 28 - Mon, Dec 8
American Airlines Logo
3:00 pm - 10:45 amORD-FLO
18h 45m2 stops
American Airlines Logo
6:15 am - 1:08 pmFLO-ORD
7h 53m2 stops
$487American Airlines
Find Deal
Thu, Nov 27 - Mon, Dec 8
American Airlines Logo
5:15 pm - 10:53 pmPIA-FLO
4h 38m1 stop
American Airlines Logo
6:31 pm - 12:07 amFLO-PIA
6h 36m1 stop
$491American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
10:45 am - 10:53 pmPIA-FLO
11h 08m2 stops
American Airlines Logo
6:31 pm - 12:07 amFLO-PIA
6h 36m1 stop
$496American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
10:45 am - 10:53 pmPIA-FLO
11h 08m2 stops
American Airlines Logo
11:16 am - 7:42 pmFLO-PIA
9h 26m2 stops
$501American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
5:15 pm - 10:53 pmPIA-FLO
4h 38m1 stop
American Airlines Logo
6:31 pm - 12:07 amFLO-PIA
6h 36m1 stop
$511American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
10:52 am - 10:53 pmPIA-FLO
11h 01m2 stops
American Airlines Logo
6:31 pm - 12:07 amFLO-PIA
6h 36m1 stop
$516American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
10:45 am - 10:53 pmPIA-FLO
11h 08m2 stops
American Airlines Logo
5:15 am - 3:45 pmFLO-PIA
11h 30m2 stops
$521American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13

American Airlines flights from Illinois to Florence, South Carolina

Our best American Airlines deals on Illinois to Florence, South Carolina flight tickets
American Airlines
Sep 3
MLI3:26 pmMoline Quad-City
6h 50m
1 stop
FLO11:16 pmFlorence
Sep 6
FLO5:37 pmFlorence
6h 33m
1 stop
MLI11:10 pmMoline Quad-City
$391
Find similar
American Airlines
Nov 27
ORD5:00 amChicago O'Hare Intl
4h 45m
1 stop
FLO10:45 amFlorence
Dec 8
FLO5:35 pmFlorence
7h 04m
1 stop
ORD11:39 pmChicago O'Hare Intl
$393
Find similar
American Airlines
Sep 3
MLI6:00 amMoline Quad-City
10h 12m
2 stops
FLO5:12 pmFlorence
Sep 6
FLO5:37 pmFlorence
6h 33m
1 stop
MLI11:10 pmMoline Quad-City
$396
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Illinois to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 1, 2025.
Use the filters below to find and compare flights from Illinois to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Thu 11/27

5:00 am-10:45 am

1 stop4h 45m

Florence

Mon 12/8

5:35 pm-11:39 pm

1 stop7h 04m

$393

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Thu 11/27

5:00 am-10:45 am

1 stop4h 45m

Florence

Mon 12/8

10:28 am-4:51 pm

2 stops7h 23m

$398

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Fri 11/28

4:02 pm-12:03 am

2 stops7h 01m

Florence

Mon 12/8

10:28 am-4:51 pm

2 stops7h 23m

$454

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Thu 11/27

3:00 pm-10:45 am

2 stops18h 45m

Florence

Mon 12/8

6:15 am-1:08 pm

2 stops7h 53m

$487

PeoriaFlorence

PIA - FLO

PIAFLO

Greater Peoria

Wed 12/10

5:15 pm-10:53 pm

1 stop4h 38m

Florence

Sat 12/13

6:31 pm-12:07 am

1 stop6h 36m

$491

PeoriaFlorence

PIA - FLO

PIAFLO

Greater Peoria

Wed 12/10

10:45 am-10:53 pm

2 stops11h 08m

Florence

Sat 12/13

6:31 pm-12:07 am

1 stop6h 36m

$496

PeoriaFlorence

PIA - FLO

PIAFLO

Greater Peoria

Wed 12/10

10:45 am-10:53 pm

2 stops11h 08m

Florence

Sat 12/13

11:16 am-7:42 pm

2 stops9h 26m

$501

PeoriaFlorence

PIA - FLO

PIAFLO

Greater Peoria

Wed 12/10

5:15 pm-10:53 pm

1 stop4h 38m

Florence

Sat 12/13

6:31 pm-12:07 am

1 stop6h 36m

$511

PeoriaFlorence

PIA - FLO

PIAFLO

Greater Peoria

Wed 12/10

10:52 am-10:53 pm

2 stops11h 01m

Florence

Sat 12/13

6:31 pm-12:07 am

1 stop6h 36m

$516

PeoriaFlorence

PIA - FLO

PIAFLO

Greater Peoria

Wed 12/10

10:45 am-10:53 pm

2 stops11h 08m

Florence

Sat 12/13

5:15 am-3:45 pm

2 stops11h 30m

$521

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Illinois to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Illinois is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $437. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from Illinois because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $449.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the afternoon. momondo users have found flights departing from Illinois to Florence, South Carolina in the afternoon for as low as $437. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $477 per ticket.

Cheap Illinois to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Illinois to Florence, South Carolina

Direct flights

None
There are no direct flights from Illinois to Florence, South Carolina. There are no popular flight routes from Illinois to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Illinois to Florence Airport?

    Prices for flights from Illinois to Florence Airport are updated daily.

  • How many operators does momondo search for flights from Illinois to Florence Airport?

  • How old do you have to be to fly from Illinois to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Illinois to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Illinois to Florence, South Carolina

Compare and see reviews for airlines that fly from Illinois to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $290Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Illinois to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Illinois to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Illinois to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Illinois with this policy.

How can momondo help me find flights from Illinois to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Illinois to Florence.

I’m not ready to book a flight from Illinois to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Illinois to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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