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Cheap flights from Harrisburg to South Carolina from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to South Carolina departing on 2/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Harrisburg to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
11:40 am - 1:08 pm
MDT
-
MYR
1h 28mnonstop
Allegiant Air Logo
2:03 pm - 3:41 pm
MYR
-
MDT
1h 38mnonstop
$176Allegiant Air
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
7:52 pm - 11:58 pm
MDT
-
SAV
4h 06m1 stop
American Airlines Logo
5:00 am - 10:57 am
SAV
-
MDT
5h 57m1 stop
$195American Airlines
Sat, Feb 14 - Sat, Feb 21
Delta Logo
12:28 pm - 6:55 pm
MDT
-
SAV
6h 27m1 stop
Delta Logo
4:52 pm - 11:47 pm
SAV
-
MDT
6h 55m1 stop
$197Delta
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
10:34 am - 2:47 pm
MDT
-
SAV
4h 13m1 stop
United Airlines Logo
10:10 am - 4:34 pm
SAV
-
MDT
6h 24m1 stop
$222United Airlines
Tue, Jan 6 - Tue, Jan 13
American Airlines Logo
3:08 pm - 9:00 pm
MDT
-
SAV
5h 52m2 stops
American Airlines Logo
7:00 am - 12:13 pm
SAV
-
MDT
5h 13m1 stop
$227American Airlines
Tue, Jan 6 - Tue, Jan 13
American Airlines Logo
12:53 pm - 5:09 pm
MDT
-
GSP
4h 16m1 stop
American Airlines Logo
5:40 pm - 11:37 pm
GSP
-
MDT
5h 57m1 stop
$229American Airlines
Sat, Jan 31 - Tue, Feb 3
Delta Logo
6:00 am - 3:43 pm
MDT
-
SAV
9h 43m2 stops
Delta Logo
4:52 pm - 11:47 pm
SAV
-
MDT
6h 55m1 stop
$233Delta
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
6:29 am - 1:52 pm
MDT
-
CHS
7h 23m1 stop
United Airlines Logo
10:20 am - 4:44 pm
CHS
-
MDT
6h 24m1 stop
$249United Airlines
Sat, Feb 14 - Wed, Feb 18
Allegiant Air Logo
9:02 pm - 3:07 pm
MDT
-
CAE
18h 05m1 stop
Allegiant Air Logo
2:37 pm - 8:27 am
CAE
-
MDT
17h 50m1 stop
$277Allegiant Air
Sat, Dec 20 - Sat, Dec 27
Frontier Logo
10:46 am - 4:35 pm
MDT
-
CLT
5h 49m1 stop
Frontier Logo
9:52 pm - 9:51 am
CLT
-
MDT
11h 59m1 stop
$317Frontier
Fri, Feb 27 - Sun, Mar 1

American Airlines flights from Harrisburg to South Carolina

Our best American Airlines deals on Harrisburg to South Carolina flight tickets
American Airlines
Feb 14
MDT7:52 pmHarrisburg
4h 06m
1 stop
SAV11:58 pmSavannah/Hilton Head
Feb 21
SAV5:00 amSavannah/Hilton Head
5h 57m
1 stop
MDT10:57 amHarrisburg
$195
Find similar
American Airlines
Jan 6
MDT3:08 pmHarrisburg
5h 52m
2 stops
SAV9:00 pmSavannah/Hilton Head
Jan 13
SAV7:00 amSavannah/Hilton Head
5h 13m
1 stop
MDT12:13 pmHarrisburg
$227
Find similar
American Airlines
Feb 7
MDT4:49 pmHarrisburg
4h 05m
1 stop
MYR8:54 pmMyrtle Beach Intl
Feb 21
MYR6:38 pmMyrtle Beach Intl
3h 37m
1 stop
MDT10:15 pmHarrisburg
$229
Find similar

United Airlines flights from Harrisburg to South Carolina

Our best United Airlines deals on Harrisburg to South Carolina flight tickets
United Airlines
Jan 6
MDT10:34 amHarrisburg
4h 13m
1 stop
SAV2:47 pmSavannah/Hilton Head
Jan 13
SAV10:10 amSavannah/Hilton Head
6h 24m
1 stop
MDT4:34 pmHarrisburg
$222
Find similar
United Airlines
Feb 14
MDT6:29 amHarrisburg
7h 23m
1 stop
CHS1:52 pmCharleston
Feb 18
CHS10:20 amCharleston
6h 24m
1 stop
MDT4:44 pmHarrisburg
$249
Find similar
United Airlines
Dec 25
MDT6:30 amHarrisburg
7h 59m
1 stop
SAV2:29 pmSavannah/Hilton Head
Dec 29
SAV4:55 pmSavannah/Hilton Head
7h 12m
1 stop
MDT12:07 amHarrisburg
$267
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Thu 4/9

11:40 am-1:08 pm

Nonstop1h 28m

Myrtle Beach Intl

Sun 4/12

2:03 pm-3:41 pm

Nonstop1h 38m

$176

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Sat 2/14

7:52 pm-11:58 pm

1 stop4h 06m

Savannah/Hilton Head

Sat 2/21

5:00 am-10:57 am

1 stop5h 57m

$195

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Tue 3/24

12:28 pm-6:55 pm

1 stop6h 27m

Savannah/Hilton Head

Tue 3/31

4:52 pm-11:47 pm

1 stop6h 55m

$197

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Tue 1/6

10:34 am-2:47 pm

1 stop4h 13m

Savannah/Hilton Head

Tue 1/13

10:10 am-4:34 pm

1 stop6h 24m

$222

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Tue 1/6

3:08 pm-9:00 pm

2 stops5h 52m

Savannah/Hilton Head

Tue 1/13

7:00 am-12:13 pm

1 stop5h 13m

$227

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 1/31

12:53 pm-5:09 pm

1 stop4h 16m

Greenville

Tue 2/3

5:40 pm-11:37 pm

1 stop5h 57m

$229

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Tue 3/24

6:00 am-3:43 pm

2 stops9h 43m

Savannah/Hilton Head

Tue 3/31

4:52 pm-11:47 pm

1 stop6h 55m

$233

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Sat 2/14

6:29 am-1:52 pm

1 stop7h 23m

Charleston

Wed 2/18

10:20 am-4:44 pm

1 stop6h 24m

$249

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

Sat 12/20

9:02 pm-3:07 pm

1 stop18h 05m

Columbia Metropolitan

Sat 12/27

2:37 pm-8:27 am

1 stop17h 50m

$277

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Fri 2/27

10:46 am-4:35 pm

1 stop5h 49m

Charlotte Douglas

Sun 3/1

9:52 pm-9:51 am

1 stop11h 59m

$317

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Harrisburg to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Harrisburg is in August. Flight prices, which tend to average around $291, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Harrisburg during May instead. Flights to South Carolina in May, while not as cheap as those in August, still average around $298.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $328. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $422.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Harrisburg to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $333. Try not to purchase tickets in the afternoon because they tend to be around $393. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Harrisburg to South Carolina flight route?

Fly from Harrisburg to Myrtle Beach Intl for the best Harrisburg - South Carolina flight prices

What cabin class options are available on Harrisburg to South Carolina flights?

There is only 1 cabin class available to choose from on Harrisburg to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Harrisburg to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Harrisburg to South Carolina.

Cheap Harrisburg to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to South Carolina

Fastest flight time

1h 39m

Direct flights

Every day

Airports in South Carolina

57 airports
The fastest flight from Harrisburg to South Carolina takes 1h 39m
Direct flights go from Harrisburg to South Carolina every day.
There are 57 airports in South Carolina. From Harrisburg there are direct flights to Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).
Search flight deals

  • When did momondo last update prices for flights from Harrisburg Airport to South Carolina?

    Prices for flights from Harrisburg Airport to South Carolina refresh daily.

  • How many operators does momondo search for flights from Harrisburg Airport to South Carolina?

  • How old do you have to be to fly from Harrisburg Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Harrisburg Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Harrisburg to South Carolina?

Best airlines flying from Harrisburg to South Carolina

Compare and see reviews for airlines that fly from Harrisburg to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $101Free CancellationRating
7.2
699 reviews
Search Allegiant Air flights
DeltaPriceFrom $164Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $213Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
United AirlinesPriceFrom $233Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Harrisburg to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Harrisburg to South Carolina with flexible booking policies on momondo?

Flights from Harrisburg to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Harrisburg to South Carolina?

Once all potential Harrisburg to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Harrisburg to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Harrisburg are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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