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Cheap flights from Harrisburg to South Carolina from $98

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to South Carolina departing on 11/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Harrisburg to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:00 pm - 7:22 pmMDT-SAV
4h 22m1 stop
United Airlines Logo
4:55 pm - 12:07 amSAV-MDT
7h 12m1 stop
$195United Airlines
Find Deal
Sat, Dec 13 - Sat, Dec 20
United Airlines Logo
6:30 am - 2:27 pmMDT-SAV
7h 57m1 stop
United Airlines Logo
10:12 am - 4:53 pmSAV-MDT
6h 41m1 stop
$222United Airlines
Find Deal
Sun, Dec 7 - Sat, Dec 13
Delta Logo
6:00 am - 11:00 amMDT-SAV
5h 00m1 stop
Delta Logo
12:30 pm - 11:07 pmSAV-MDT
10h 37m2 stops
$228Delta
Find Deal
Wed, Dec 3 - Sat, Dec 6
American Airlines Logo
5:00 am - 10:51 amMDT-GSP
5h 51m1 stop
American Airlines Logo
5:25 am - 9:01 amGSP-MDT
3h 36m1 stop
$229American Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
United Airlines Logo
10:45 am - 4:43 pmMDT-CAE
5h 58m1 stop
United Airlines Logo
8:00 am - 2:15 pmCAE-MDT
6h 15m1 stop
$229United Airlines
Find Deal
Thu, Dec 4 - Sat, Jan 10
Delta Logo
6:00 am - 2:03 pmMDT-SAV
8h 03m2 stops
Delta Logo
12:30 pm - 11:07 pmSAV-MDT
10h 37m2 stops
$233Delta
Find Deal
Wed, Dec 3 - Sat, Dec 6
American Airlines Logo
6:40 am - 10:30 amMDT-CAE
3h 50m1 stop
American Airlines Logo
1:51 pm - 8:14 pmCAE-MDT
6h 23m2 stops
$234American Airlines
Find Deal
Thu, Dec 4 - Sat, Jan 10
Multiple Airlines Logo
8:57 pm - 1:32 pmMDT-CLT
16h 35m1 stop
Multiple Airlines Logo
3:51 pm - 9:19 amCLT-MDT
17h 28m1 stop
$254Multiple Airlines
Find Deal
Mon, Nov 17 - Thu, Nov 20
Multiple Airlines Logo
8:57 pm - 1:32 pmMDT-CLT
16h 35m1 stop
Multiple Airlines Logo
6:09 pm - 9:19 amCLT-MDT
15h 10m1 stop
$260Multiple Airlines
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Mon, Nov 17 - Thu, Nov 20
Allegiant Air Logo
8:47 pm - 3:42 pmMDT-GSP
18h 55m1 stop
Allegiant Air Logo
3:42 pm - 3:20 pmGSP-MDT
23h 38m1 stop
$554Allegiant Air
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Wed, Nov 26 - Sun, Nov 30

American Airlines flights from Harrisburg to South Carolina

Our best American Airlines deals on Harrisburg to South Carolina flight tickets
American Airlines
Dec 4
MDT5:00 amHarrisburg
5h 51m
1 stop
GSP10:51 amGreenville
Dec 11
GSP5:25 amGreenville
3h 36m
1 stop
MDT9:01 amHarrisburg
$229
Find similar
American Airlines
Dec 4
MDT6:40 amHarrisburg
3h 50m
1 stop
CAE10:30 amColumbia Metropolitan
Jan 10
CAE1:51 pmColumbia Metropolitan
6h 23m
2 stops
MDT8:14 pmHarrisburg
$234
Find similar
American Airlines
Jan 8
MDT4:47 pmHarrisburg
4h 24m
1 stop
CHS9:11 pmCharleston
Jan 11
CHS4:07 pmCharleston
4h 07m
1 stop
MDT8:14 pmHarrisburg
$237
Find similar

Frontier flights from Harrisburg to South Carolina

Our best Frontier deals on Harrisburg to South Carolina flight tickets
Frontier
Nov 25
MDT11:08 amHarrisburg
21h 08m
1 stop
CLT8:16 amCharlotte Douglas
Nov 28
CLT11:56 amCharlotte Douglas
22h 17m
1 stop
MDT10:13 amHarrisburg
$298
Find similar
Frontier
Nov 25
MDT11:08 amHarrisburg
20h 46m
2 stops
CLT7:54 amCharlotte Douglas
Nov 28
CLT11:56 amCharlotte Douglas
22h 17m
1 stop
MDT10:13 amHarrisburg
$315
Find similar
Frontier
Nov 7
MDT8:57 pmHarrisburg
15h 26m
1 stop
CLT12:23 pmCharlotte Douglas
Nov 9
CLT9:20 pmCharlotte Douglas
22h 52m
1 stop
MDT8:12 pmHarrisburg
$356
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Sat 12/13

3:00 pm-7:22 pm

1 stop4h 22m

Savannah/Hilton Head

Sat 12/20

4:55 pm-12:07 am

1 stop7h 12m

$195

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Sun 12/7

6:30 am-2:27 pm

1 stop7h 57m

Savannah/Hilton Head

Sat 12/13

10:12 am-4:53 pm

1 stop6h 41m

$222

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Wed 12/3

6:00 am-11:00 am

1 stop5h 00m

Savannah/Hilton Head

Sat 12/6

12:30 pm-11:07 pm

2 stops10h 37m

$228

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 12/4

5:00 am-10:51 am

1 stop5h 51m

Greenville

Thu 12/11

5:25 am-9:01 am

1 stop3h 36m

$229

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

Thu 12/4

10:45 am-4:43 pm

1 stop5h 58m

Columbia Metropolitan

Sat 1/10

8:00 am-2:15 pm

1 stop6h 15m

$229

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Wed 12/3

6:00 am-2:03 pm

2 stops8h 03m

Savannah/Hilton Head

Sat 12/6

12:30 pm-11:07 pm

2 stops10h 37m

$233

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

Thu 12/4

6:40 am-10:30 am

1 stop3h 50m

Columbia Metropolitan

Sat 1/10

1:51 pm-8:14 pm

2 stops6h 23m

$234

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Mon 11/17

8:57 pm-1:32 pm

1 stop16h 35m

Charlotte Douglas

Thu 11/20

3:51 pm-9:19 am

1 stop17h 28m

$254

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Mon 11/17

8:57 pm-1:32 pm

1 stop16h 35m

Charlotte Douglas

Thu 11/20

6:09 pm-9:19 am

1 stop15h 10m

$260

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 11/26

8:47 pm-3:42 pm

1 stop18h 55m

Greenville

Sun 11/30

3:42 pm-3:20 pm

1 stop23h 38m

$554

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Harrisburg to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Harrisburg is in August. Flight prices, which tend to average around $291, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Harrisburg during May instead. Flights to South Carolina in May, while not as cheap as those in August, still average around $293.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $328. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $422.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Harrisburg to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $333. Try not to purchase tickets in the afternoon because they tend to be around $393. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Harrisburg to South Carolina flight route?

Fly from Harrisburg to Myrtle Beach Intl for the best Harrisburg - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Harrisburg when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $354 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Harrisburg for as low as $248 on momondo.

What cabin class options are available on Harrisburg to South Carolina flights?

There is only 1 cabin class available to choose from on Harrisburg to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Harrisburg to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Harrisburg to South Carolina.

Cheap Harrisburg to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to South Carolina

Best Price Found

$177

Fastest flight time

1h 28m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sat

Airports in South Carolina

2 airports
The best one-way flight to South Carolina from Harrisburg in the past 72 hours is $177. The best round-trip flight deal from Harrisburg to South Carolina found on momondo in the last 72 hours is $142.
The fastest flight from Harrisburg to South Carolina takes 1h 28m
Direct flights go from Harrisburg to South Carolina on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. The only airline offering direct flights is Allegiant Air.
There are 2 airports near South Carolina: Myrtle Beach Intl (MYR), Charlotte Douglas (CLT)
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  • When did momondo last update prices for flights from Harrisburg Airport to South Carolina?

    Prices for flights from Harrisburg Airport to South Carolina refresh daily.

  • How many operators does momondo search for flights from Harrisburg Airport to South Carolina?

  • How old do you have to be to fly from Harrisburg Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Harrisburg Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Harrisburg to South Carolina?

Best airlines flying from Harrisburg to South Carolina

Compare and see reviews for airlines that fly from Harrisburg to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $101Free CancellationRating
7.2
697 reviews
Search Allegiant Air flights
DeltaPriceFrom $164Free CancellationRating
7.9
8,004 reviews
Search Delta flights
American AirlinesPriceFrom $213Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights
United AirlinesPriceFrom $233Free CancellationRating
7.4
9,002 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Harrisburg to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Harrisburg to South Carolina with flexible booking policies on momondo?

Flights from Harrisburg to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Harrisburg to South Carolina?

Once all potential Harrisburg to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Harrisburg to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Harrisburg are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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