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Cheap flights from Harrisburg to South Carolina from $71

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to South Carolina departing on 10/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Harrisburg to South Carolina

Cheap round-trip flights

Allegiant Air Logo
12:17 pm - 1:46 pmMDT-MYR
1h 29mnonstop
Allegiant Air Logo
5:56 pm - 7:31 pmMYR-MDT
1h 35mnonstop
$133Allegiant Air
Find Deal
Sun, Sep 28 - Sun, Oct 5
Allegiant Air Logo
3:37 pm - 5:06 pmMDT-MYR
1h 29mnonstop
Allegiant Air Logo
5:56 pm - 7:31 pmMYR-MDT
1h 35mnonstop
$135Allegiant Air
Find Deal
Thu, Oct 2 - Sun, Oct 5
United Airlines Logo
6:30 am - 2:44 pmMDT-SAV
8h 14m1 stop
United Airlines Logo
1:15 pm - 9:25 pmSAV-MDT
8h 10m1 stop
$195United Airlines
Find Deal
Tue, Oct 21 - Sat, Oct 25
Frontier Logo
8:31 pm - 12:44 pmMDT-CLT
16h 13m1 stop
Frontier Logo
12:05 pm - 5:36 pmCLT-MDT
5h 31m1 stop
$207Frontier
Find Deal
Fri, Oct 10 - Fri, Oct 17
Delta Logo
6:25 pm - 11:58 pmMDT-SAV
5h 33m1 stop
Delta Logo
5:37 pm - 11:08 pmSAV-MDT
5h 31m1 stop
$217Delta
Find Deal
Tue, Oct 21 - Sat, Oct 25
American Airlines Logo
4:45 pm - 8:33 pmMDT-SAV
3h 48m1 stop
American Airlines Logo
5:00 am - 9:08 amSAV-MDT
4h 08m1 stop
$222American Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
American Airlines Logo
4:25 pm - 9:06 pmMDT-CHS
4h 41m1 stop
American Airlines Logo
5:38 pm - 9:43 pmCHS-MDT
4h 05m1 stop
$224American Airlines
Find Deal
Mon, Nov 24 - Wed, Dec 3
Delta Logo
12:20 pm - 5:41 pmMDT-GSP
5h 21m1 stop
Delta Logo
6:44 pm - 11:00 pmGSP-MDT
4h 16m1 stop
$229Delta
Find Deal
Sat, Oct 18 - Wed, Oct 22
Frontier Logo
8:31 pm - 12:44 pmMDT-CLT
16h 13m1 stop
Frontier Logo
11:54 am - 5:12 pmCLT-MDT
5h 18m1 stop
$233Frontier
Find Deal
Fri, Oct 10 - Mon, Oct 13
United Airlines Logo
6:30 am - 1:36 pmMDT-GSP
7h 06m1 stop
United Airlines Logo
10:00 am - 1:58 pmGSP-MDT
3h 58m1 stop
$247United Airlines
Find Deal
Sat, Oct 18 - Sat, Nov 1

American Airlines flights from Harrisburg to South Carolina

Our best American Airlines deals on Harrisburg to South Carolina flight tickets
American Airlines
Oct 4
MDT4:45 pmHarrisburg
3h 48m
1 stop
SAV8:33 pmSavannah/Hilton Head
Oct 11
SAV5:00 amSavannah/Hilton Head
4h 08m
1 stop
MDT9:08 amHarrisburg
$222
Find similar
American Airlines
Nov 24
MDT4:25 pmHarrisburg
4h 41m
1 stop
CHS9:06 pmCharleston
Dec 3
CHS5:38 pmCharleston
4h 05m
1 stop
MDT9:43 pmHarrisburg
$224
Find similar
American Airlines
Oct 31
MDT3:07 pmHarrisburg
5h 36m
1 stop
CHS8:43 pmCharleston
Nov 6
CHS6:00 amCharleston
4h 24m
1 stop
MDT10:24 amHarrisburg
$226
Find similar

Frontier flights from Harrisburg to South Carolina

Our best Frontier deals on Harrisburg to South Carolina flight tickets
Frontier
Oct 10
MDT8:31 pmHarrisburg
16h 13m
1 stop
CLT12:44 pmCharlotte Douglas
Oct 17
CLT12:05 pmCharlotte Douglas
5h 31m
1 stop
MDT5:36 pmHarrisburg
$207
Find similar
Frontier
Sep 12
MDT11:07 amHarrisburg
25h 54m
1 stop
CLT1:01 pmCharlotte Douglas
Sep 14
CLT8:51 pmCharlotte Douglas
13h 11m
1 stop
MDT10:02 amHarrisburg
$212
Find similar
Frontier
Oct 10
MDT8:31 pmHarrisburg
16h 13m
1 stop
CLT12:44 pmCharlotte Douglas
Oct 13
CLT11:54 amCharlotte Douglas
5h 18m
1 stop
MDT5:12 pmHarrisburg
$233
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 10, 2025.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sun 9/28

12:17 pm-1:46 pm

Nonstop1h 29m

Myrtle Beach Intl

Sun 10/5

5:56 pm-7:31 pm

Nonstop1h 35m

$133

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Thu 10/2

3:37 pm-5:06 pm

Nonstop1h 29m

Myrtle Beach Intl

Sun 10/5

5:56 pm-7:31 pm

Nonstop1h 35m

$135

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Tue 10/21

6:30 am-2:44 pm

1 stop8h 14m

Savannah/Hilton Head

Sat 10/25

1:15 pm-9:25 pm

1 stop8h 10m

$195

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Fri 10/10

8:31 pm-12:44 pm

1 stop16h 13m

Charlotte Douglas

Fri 10/17

12:05 pm-5:36 pm

1 stop5h 31m

$207

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Tue 10/21

6:25 pm-11:58 pm

1 stop5h 33m

Savannah/Hilton Head

Sat 10/25

5:37 pm-11:08 pm

1 stop5h 31m

$217

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Sat 10/4

4:45 pm-8:33 pm

1 stop3h 48m

Savannah/Hilton Head

Sat 10/11

5:00 am-9:08 am

1 stop4h 08m

$222

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Mon 11/24

4:25 pm-9:06 pm

1 stop4h 41m

Charleston

Wed 12/3

5:38 pm-9:43 pm

1 stop4h 05m

$224

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 10/18

12:20 pm-5:41 pm

1 stop5h 21m

Greenville

Wed 10/22

6:44 pm-11:00 pm

1 stop4h 16m

$229

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Fri 10/10

8:31 pm-12:44 pm

1 stop16h 13m

Charlotte Douglas

Mon 10/13

11:54 am-5:12 pm

1 stop5h 18m

$233

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 10/18

6:30 am-1:36 pm

1 stop7h 06m

Greenville

Sat 11/1

10:00 am-1:58 pm

1 stop3h 58m

$247

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Harrisburg to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Harrisburg is in October. Flight prices, which tend to average around $258, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of October, then book flights to South Carolina from Harrisburg during May instead. Flights to South Carolina in May, while not as cheap as those in October, still average around $313.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $328. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $422.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Harrisburg to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $333. Try not to purchase tickets in the afternoon because they tend to be around $393. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Harrisburg to South Carolina flight route?

Fly from Harrisburg to Myrtle Beach Intl for the best Harrisburg - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Harrisburg when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $350 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Harrisburg for as low as $248 on momondo.

What cabin class options are available on Harrisburg to South Carolina flights?

There is only 1 cabin class available to choose from on Harrisburg to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Harrisburg to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Harrisburg to South Carolina.

Cheap Harrisburg to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to South Carolina

Best Price Found

$118

Fastest flight time

1h 29m

Direct flights

Every day

Airports in South Carolina

2 airports
The best one-way flight to South Carolina from Harrisburg in the past 72 hours is $118. The best round-trip flight deal from Harrisburg to South Carolina found on momondo in the last 72 hours is $137.
The fastest flight from Harrisburg to South Carolina takes 1h 29m
Direct flights go from Harrisburg to South Carolina every day.
There are 2 airports near South Carolina: Myrtle Beach Intl (MYR), Charlotte Douglas (CLT)
Search flight deals

  • When did momondo last update prices for flights from Harrisburg Airport to South Carolina?

    Prices for flights from Harrisburg Airport to South Carolina refresh daily.

  • How many operators does momondo search for flights from Harrisburg Airport to South Carolina?

  • How old do you have to be to fly from Harrisburg Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Harrisburg Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Harrisburg to South Carolina?

Best airlines flying from Harrisburg to South Carolina

Compare and see reviews for airlines that fly from Harrisburg to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $100Free CancellationRating
7.2
702 reviews
Search Allegiant Air flights
DeltaPriceFrom $164Free CancellationRating
7.9
7,963 reviews
Search Delta flights
American AirlinesPriceFrom $213Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $233Free CancellationRating
7.4
8,937 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Harrisburg to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Harrisburg to South Carolina with flexible booking policies on momondo?

Flights from Harrisburg to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Harrisburg to South Carolina?

Once all potential Harrisburg to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Harrisburg to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Harrisburg are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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