What is the cheapest airline that flies from Harrisburg to South Carolina?

Delta, Allegiant Air, and American Airlines are the most popular carriers operating from Harrisburg to South Carolina

How many flights depart from Harrisburg to South Carolina on average per week?

33 flights are operational weekly from Harrisburg to South Carolina as of August 2026. The most popular departure day for this route is Mon, with 18% of flights per week taking off on this day.

What airlines fly to South Carolina?

Southwest, American Airlines and Allegiant Air are the top three most popular airlines that fly to South Carolina from Harrisburg according to our data. Southwest is the first choice among our users, with 47% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Harrisburg Airport to South Carolina?

Prices for flights from Harrisburg Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Harrisburg Airport to South Carolina?

As of August 2026, there are 4 operators available to choose from for flights from Harrisburg Airport to South Carolina.

How old do you have to be to fly from Harrisburg Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Harrisburg Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$66 Cheap Flights from Harrisburg to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Harrisburg to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:26 pm - 4:02 pmMDT Harrisburg-MYR Myrtle Beach Intl

1h 36mnonstop

4:52 pm - 6:23 pmMYR Myrtle Beach Intl-MDT Harrisburg

1h 31mnonstop

$117Allegiant Air

Sun, Aug 30 - Thu, Sep 3

3:58 pm - 5:28 pmMDT Harrisburg-MYR Myrtle Beach Intl

1h 30mnonstop

6:54 pm - 8:30 pmMYR Myrtle Beach Intl-MDT Harrisburg

1h 36mnonstop

$133Allegiant Air

Sun, Oct 11 - Thu, Oct 15

6:00 am - 10:11 amMDT Harrisburg-CLT Charlotte Douglas

4h 11m1 stop Atlanta Hartsfield-Jackson

5:00 pm - 11:15 pmCLT Charlotte Douglas-MDT Harrisburg

6h 15m1 stop Detroit Metropolitan Wayne County

$167Delta

Thu, Sep 3 - Wed, Sep 9

6:00 am - 11:03 amMDT Harrisburg-CLT Charlotte Douglas

5h 03m1 stop Atlanta Hartsfield-Jackson

7:40 am - 11:49 amCLT Charlotte Douglas-MDT Harrisburg

4h 09m1 stop Atlanta Hartsfield-Jackson

$167Delta

Fri, Aug 28 - Tue, Sep 1

6:43 am - 12:33 pmMDT Harrisburg-CHS Charleston

5h 50m1 stop Philadelphia

6:00 am - 10:17 amCHS Charleston-MDT Harrisburg

4h 17m1 stop Philadelphia

$285American Airlines

Wed, Oct 21 - Sat, Oct 24

6:00 am - 9:47 amMDT Harrisburg-CHS Charleston

3h 47m1 stop Charlotte Douglas

6:20 am - 10:17 amCHS Charleston-MDT Harrisburg

3h 57m1 stop Charlotte Douglas

$285American Airlines

Sat, Sep 12 - Sat, Sep 19

2:40 pm - 7:11 pmMDT Harrisburg-CHS Charleston

4h 31m1 stop Washington, D.C. Dulles Intl

3:02 pm - 6:36 pmCHS Charleston-MDT Harrisburg

3h 34m1 stop Washington, D.C. Dulles Intl

$285United Airlines

Wed, Oct 28 - Sat, Oct 31

6:30 am - 12:10 pmMDT Harrisburg-SAV Savannah/Hilton Head

5h 40m1 stop Chicago O'Hare Intl

1:06 pm - 8:58 pmSAV Savannah/Hilton Head-MDT Harrisburg

7h 52m1 stop Chicago O'Hare Intl

$295United Airlines

Sat, Sep 12 - Sat, Sep 19

3:59 pm - 10:05 amMDT Harrisburg-MYR Myrtle Beach Intl

42h 06m2 stops Nashville Intl Orlando

4:52 pm - 6:23 pmMYR Myrtle Beach Intl-MDT Harrisburg

1h 31mnonstop

$305Multiple Airlines

Sun, Aug 30 - Thu, Sep 3

4:07 pm - 5:37 pmMDT Harrisburg-MYR Myrtle Beach Intl

1h 30mnonstop

6:25 pm - 8:26 pmMYR Myrtle Beach Intl-MDT Harrisburg

26h 01m1 stop Tampa

$315Multiple Airlines

Sun, Oct 4 - Thu, Oct 8

Cheap last minute flights

Enter your travel dates to find the best prices.

2:26 pm - 4:02 pmMDT Harrisburg-MYR Myrtle Beach Intl

1h 36mnonstop

4:52 pm - 6:25 pmMYR Myrtle Beach Intl-MDT Harrisburg

1h 33mnonstop

$245Allegiant Air

Sun, Aug 23 - Sun, Aug 30

2:26 pm - 4:02 pmMDT Harrisburg-MYR Myrtle Beach Intl

1h 36mnonstop

4:52 pm - 6:25 pmMYR Myrtle Beach Intl-MDT Harrisburg

1h 33mnonstop

$258Allegiant Air

Sun, Aug 23 - Sun, Aug 30

2:26 pm - 4:02 pmMDT Harrisburg-MYR Myrtle Beach Intl

1h 36mnonstop

2:58 pm - 10:54 amMYR Myrtle Beach Intl-MDT Harrisburg

19h 56m1 stop Orlando

$336Multiple Airlines

Sun, Aug 23 - Sun, Aug 30

3:59 pm - 9:05 amMDT Harrisburg-MYR Myrtle Beach Intl

41h 06m2 stops Nashville Intl Orlando

4:52 pm - 6:23 pmMYR Myrtle Beach Intl-MDT Harrisburg

1h 31mnonstop

$361Multiple Airlines

Thu, Aug 20 - Thu, Sep 3

4:49 pm - 9:44 pmMDT Harrisburg-SAV Savannah/Hilton Head

4h 55m1 stop Charlotte Douglas

6:55 pm - 11:03 pmSAV Savannah/Hilton Head-MDT Harrisburg

4h 08m1 stop Philadelphia

$365American Airlines

Sat, Aug 22 - Wed, Aug 26

6:15 am - 10:24 amMDT Harrisburg-GSP Greenville

4h 09m1 stop Philadelphia

5:30 am - 9:02 amGSP Greenville-MDT Harrisburg

3h 32m1 stop Charlotte Douglas

$369American Airlines

Fri, Aug 21 - Sun, Aug 23

3:03 pm - 9:20 pmMDT Harrisburg-CAE Columbia Metropolitan

6h 17m1 stop Atlanta Hartsfield-Jackson

6:08 pm - 11:43 pmCAE Columbia Metropolitan-MDT Harrisburg

5h 35m1 stop Atlanta Hartsfield-Jackson

$389Delta

Fri, Aug 21 - Sun, Aug 23

6:30 am - 1:58 pmMDT Harrisburg-CHS Charleston

7h 28m1 stop Chicago O'Hare Intl

8:55 am - 4:52 pmCHS Charleston-MDT Harrisburg

7h 57m1 stop Chicago O'Hare Intl

$403United Airlines

Sat, Aug 22 - Tue, Sep 22

6:24 pm - 11:59 pmMDT Harrisburg-CHS Charleston

5h 35m1 stop Atlanta Hartsfield-Jackson

5:10 am - 11:08 amCHS Charleston-MDT Harrisburg

5h 58m1 stop Atlanta Hartsfield-Jackson

$409Delta

Fri, Aug 21 - Mon, Aug 24

10:40 am - 5:17 pmMDT Harrisburg-CLT Charlotte Douglas

6h 37m1 stop Chicago O'Hare Intl

8:05 am - 1:32 pmCLT Charlotte Douglas-MDT Harrisburg

5h 27m1 stop Chicago O'Hare Intl

$607United Airlines

Fri, Aug 21 - Sun, Aug 23

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American Airlines flights from Harrisburg to South Carolina

Our best American Airlines deals on Harrisburg to South Carolina flight tickets

American Airlines

Oct 21

MDT6:43 amHarrisburg

5h 50m

1 stop

CHS12:33 pmCharleston

Oct 24

CHS6:00 amCharleston

4h 17m

1 stop

MDT10:17 amHarrisburg

$285

American Airlines

Sep 19

MDT11:17 amHarrisburg

5h 25m

1 stop

SAV4:42 pmSavannah/Hilton Head

Sep 30

SAV6:22 amSavannah/Hilton Head

3h 55m

1 stop

MDT10:17 amHarrisburg

$295

American Airlines

Oct 17

MDT12:18 pmHarrisburg

5h 04m

1 stop

GSP5:22 pmGreenville

Oct 20

GSP7:25 pmGreenville

4h 01m

1 stop

MDT11:26 pmHarrisburg

$299

United Airlines flights from Harrisburg to South Carolina

Our best United Airlines deals on Harrisburg to South Carolina flight tickets

United Airlines

Oct 16

MDT2:08 pmHarrisburg

6h 08m

1 stop

SAV8:16 pmSavannah/Hilton Head

Oct 24

SAV6:10 amSavannah/Hilton Head

7h 17m

1 stop

MDT1:27 pmHarrisburg

$307

United Airlines

Sep 12

MDT2:17 pmHarrisburg

6h 02m

1 stop

SAV8:19 pmSavannah/Hilton Head

Sep 19

SAV1:06 pmSavannah/Hilton Head

7h 52m

1 stop

MDT8:58 pmHarrisburg

$314

United Airlines

Sep 10

MDT6:30 amHarrisburg

5h 40m

1 stop

SAV12:10 pmSavannah/Hilton Head

Sep 14

SAV7:30 pmSavannah/Hilton Head

4h 00m

1 stop

MDT11:30 pmHarrisburg

$319

momondo Fare Finder

Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgMyrtle Beach

MDT Harrisburg - MYR Myrtle Beach Intl

MDTMYR

Harrisburg

Sun 8/30

2:26 pm-4:02 pm

Nonstop1h 36m

Myrtle Beach Intl

Thu 9/3

4:52 pm-6:23 pm

Nonstop1h 31m

$117

Quickest round-trip

HarrisburgMyrtle Beach

MDT Harrisburg - MYR Myrtle Beach Intl

MDTMYR

Harrisburg

Sun 10/11

3:58 pm-5:28 pm

Nonstop1h 30m

Myrtle Beach Intl

Thu 10/15

6:54 pm-8:30 pm

Nonstop1h 36m

$133

HarrisburgCharlotte

MDT Harrisburg - CLT Charlotte Douglas

MDTCLT

Harrisburg

Thu 9/3

6:00 am-10:11 am

1 stop4h 11m

Charlotte Douglas

Wed 9/9

5:00 pm-11:15 pm

1 stop6h 15m

$167

HarrisburgCharlotte

MDT Harrisburg - CLT Charlotte Douglas

MDTCLT

Harrisburg

Fri 8/28

6:00 am-11:03 am

1 stop5h 03m

Charlotte Douglas

Tue 9/1

7:40 am-11:49 am

1 stop4h 09m

$167

HarrisburgCharleston

MDT Harrisburg - CHS Charleston

MDTCHS

Harrisburg

Wed 10/21

6:43 am-12:33 pm

1 stop5h 50m

Charleston

Sat 10/24

6:00 am-10:17 am

1 stop4h 17m

$285

HarrisburgCharleston

MDT Harrisburg - CHS Charleston

MDTCHS

Harrisburg

Sat 9/12

6:00 am-9:47 am

1 stop3h 47m

Charleston

Sat 9/19

6:20 am-10:17 am

1 stop3h 57m

$285

HarrisburgCharleston

MDT Harrisburg - CHS Charleston

MDTCHS

Harrisburg

Wed 10/28

2:40 pm-7:11 pm

1 stop4h 31m

Charleston

Sat 10/31

3:02 pm-6:36 pm

1 stop3h 34m

$285

HarrisburgSavannah

MDT Harrisburg - SAV Savannah/Hilton Head

MDTSAV

Harrisburg

Sat 9/12

6:30 am-12:10 pm

1 stop5h 40m

Savannah/Hilton Head

Sat 9/19

1:06 pm-8:58 pm

1 stop7h 52m

$295

HarrisburgMyrtle Beach

MDT Harrisburg - MYR Myrtle Beach Intl

MDTMYR

Harrisburg

Sun 8/30

3:59 pm-10:05 am

2 stops42h 06m

Myrtle Beach Intl

Thu 9/3

4:52 pm-6:23 pm

Nonstop1h 31m

$305

HarrisburgMyrtle Beach

MDT Harrisburg - MYR Myrtle Beach Intl

MDTMYR

Harrisburg

Sun 10/4

4:07 pm-5:37 pm

Nonstop1h 30m

Myrtle Beach Intl

Thu 10/8

6:25 pm-8:26 pm

1 stop26h 01m

$315

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Harrisburg to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Harrisburg is in June. Flight prices, which tend to average around $201, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to South Carolina from Harrisburg during August instead. Flights to South Carolina in August, while not as cheap as those in June, still average around $256.

What is the cheapest Harrisburg to South Carolina flight route?

Fly from Harrisburg to Myrtle Beach Intl for the best Harrisburg - South Carolina flight prices

What cabin class options are available on Harrisburg to South Carolina flights?

There is only 1 cabin class available to choose from on Harrisburg to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Harrisburg to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Harrisburg to South Carolina.

Cheap Harrisburg to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to South Carolina

Best Price Found	$66
Fastest flight time	1h 30m
Direct flights	Mon, Tue, Thu, Fri and Sat
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Harrisburg in the past 72 hours is $66. The best round-trip flight deal from Harrisburg to South Carolina found on momondo in the last 72 hours is $117.

The fastest flight from Harrisburg to South Carolina takes 1h 30m

Direct flights go from Harrisburg to South Carolina on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.

There are 57 airports in South Carolina. From Harrisburg there are direct flights to Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Harrisburg to South Carolina

When did momondo last update prices for flights from Harrisburg Airport to South Carolina?
Prices for flights from Harrisburg Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Harrisburg Airport to South Carolina?
As of August 2026, there are 4 operators available to choose from for flights from Harrisburg Airport to South Carolina.
How old do you have to be to fly from Harrisburg Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Harrisburg Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Harrisburg to South Carolina?
Based on momondo bookings for flights between Harrisburg and South Carolina, the leading plane model is Airbus A320-100/200, making up 41.32% of the total bookings. Other popular models include Boeing 737 MAX 8 with 37.19%, Airbus A319 with 14.05%, and Embraer ERJ-135 / ERJ-140 / ERJ-145 with 2.48%.

Best airlines flying from Harrisburg to South Carolina

Compare and see reviews for airlines that fly from Harrisburg to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $122	Free Cancellation	Rating 7.3 675 reviews	Search Allegiant Air flights
United Airlines	PriceFrom $228	Free Cancellation	Rating 7.4 10,103 reviews	Search United Airlines flights
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.1 11,954 reviews	Search American Airlines flights
Delta	PriceFrom $260	Free Cancellation	Rating 7.8 8,503 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Harrisburg to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Harrisburg to South Carolina with flexible booking policies on momondo?

Flights from Harrisburg to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Harrisburg to South Carolina?

Once all potential Harrisburg to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Harrisburg to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Harrisburg are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.