What airlines fly to St. Louis?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to St. Louis from Greenville according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 3 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Greenville to Lambert-St Louis?

American Airlines is the most popular carrier operating from Greenville to Lambert-St Louis

When did momondo last update prices for flights from Greenville Airport to Lambert-St Louis Airport?

Prices for flights from Greenville Airport to Lambert-St Louis Airport are updated daily.

How many operators does momondo search for flights from Greenville Airport to Lambert-St Louis Airport?

There are 3 operators available for flights from Greenville Airport to Lambert-St Louis Airport as of December 2025.

How old do you have to be to fly from Greenville Airport to Lambert-St Louis Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Lambert-St Louis Airport.

What documentation or ID do you need to fly to Lambert-St Louis Airport?

The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$178 Cheap Flights from Greenville to St. Louis in 2025/26

1 adult

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Find the cheapest flights from Greenville to St. Louis

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:50 am - 11:05 am

GSP

STL

5h 15m1 stop

7:10 am - 2:15 pm

STL

GSP

6h 05m1 stop

$297Delta

Tue, Jan 13 - Wed, Jan 14

11:15 am - 7:05 pm

GSP

STL

8h 50m2 stops

11:35 am - 5:35 pm

STL

GSP

5h 00m1 stop

$302Southwest

Tue, Jan 13 - Wed, Jan 14

11:15 am - 7:05 pm

GSP

STL

8h 50m2 stops

8:20 am - 5:35 pm

STL

GSP

8h 15m2 stops

$307Southwest

Tue, Jan 13 - Wed, Jan 14

9:45 am - 1:14 pm

GSP

STL

4h 29m1 stop

6:00 pm - 12:51 am

STL

GSP

5h 51m1 stop

$351American Airlines

Thu, Dec 25 - Mon, Dec 29

10:51 am - 2:30 pm

GSP

STL

4h 39m1 stop

11:20 am - 4:52 pm

STL

GSP

4h 32m1 stop

$360United Airlines

Sun, Jan 18 - Thu, Jan 22

6:35 am - 11:02 am

GSP

STL

5h 27m1 stop

12:44 pm - 11:48 pm

STL

GSP

10h 04m2 stops

$365United Airlines

Sun, Jan 18 - Thu, Jan 22

6:20 am - 2:30 pm

GSP

STL

9h 10m2 stops

12:44 pm - 11:48 pm

STL

GSP

10h 04m2 stops

$370United Airlines

Sun, Jan 18 - Thu, Jan 22

11:33 am - 10:33 pm

GSP

STL

12h 00m1 stop

4:27 pm - 3:55 pm

STL

GSP

46h 28m2 stops

$425Multiple Airlines

Thu, Dec 25 - Mon, Dec 29

4:45 pm - 10:00 pm

GSP

STL

6h 15m1 stop

10:30 am - 9:55 pm

STL

GSP

10h 25m2 stops

$441Southwest

Thu, Dec 25 - Sun, Dec 28

12:01 pm - 7:22 pm

GSP

STL

8h 21m1 stop

5:00 am - 12:19 pm

STL

GSP

6h 19m1 stop

$452American Airlines

Thu, Dec 25 - Sun, Dec 28

Delta flights from Greenville to St. Louis

Our best Delta deals on Greenville to St. Louis flight tickets

Delta

Jan 13

GSP6:50 amGreenville

5h 15m

1 stop

STL11:05 amLambert-St Louis

Jan 14

STL7:10 amLambert-St Louis

6h 05m

1 stop

GSP2:15 pmGreenville

$297

Find similar

Delta

Dec 20

GSP12:43 pmGreenville

4h 45m

1 stop

STL4:28 pmLambert-St Louis

Dec 21

STL7:02 pmLambert-St Louis

3h 30m

1 stop

GSP11:32 pmGreenville

$577

Find similar

Delta

Dec 16

GSP5:35 amGreenville

6h 10m

1 stop

STL10:45 amLambert-St Louis

Dec 19

STL6:00 amLambert-St Louis

4h 15m

1 stop

GSP11:15 amGreenville

$709

Find similar

Southwest flights from Greenville to St. Louis

Our best Southwest deals on Greenville to St. Louis flight tickets

Southwest

Jan 13

GSP11:15 amGreenville

8h 50m

2 stops

STL7:05 pmLambert-St Louis

Jan 14

STL11:35 amLambert-St Louis

5h 00m

1 stop

GSP5:35 pmGreenville

$302

Find similar

Southwest

Jan 13

GSP11:15 amGreenville

8h 50m

2 stops

STL7:05 pmLambert-St Louis

Jan 14

STL8:20 amLambert-St Louis

8h 15m

2 stops

GSP5:35 pmGreenville

$307

Find similar

Southwest

Dec 25

GSP4:45 pmGreenville

6h 15m

1 stop

STL10:00 pmLambert-St Louis

Dec 28

STL10:30 amLambert-St Louis

10h 25m

2 stops

GSP9:55 pmGreenville

$441

Find similar

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 1/13

6:50 am-11:05 am

1 stop5h 15m

Lambert-St Louis

Wed 1/14

7:10 am-2:15 pm

1 stop6h 05m

$297

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 1/13

11:15 am-7:05 pm

2 stops8h 50m

Lambert-St Louis

Wed 1/14

11:35 am-5:35 pm

1 stop5h 00m

$302

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 1/13

11:15 am-7:05 pm

2 stops8h 50m

Lambert-St Louis

Wed 1/14

8:20 am-5:35 pm

2 stops8h 15m

$307

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 12/25

9:45 am-1:14 pm

1 stop4h 29m

Lambert-St Louis

Mon 12/29

6:00 pm-12:51 am

1 stop5h 51m

$351

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 1/18

10:51 am-2:30 pm

1 stop4h 39m

Lambert-St Louis

Thu 1/22

11:20 am-4:52 pm

1 stop4h 32m

$360

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 1/18

6:35 am-11:02 am

1 stop5h 27m

Lambert-St Louis

Thu 1/22

12:44 pm-11:48 pm

2 stops10h 04m

$365

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 1/18

6:20 am-2:30 pm

2 stops9h 10m

Lambert-St Louis

Thu 1/22

12:44 pm-11:48 pm

2 stops10h 04m

$370

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 12/25

11:33 am-10:33 pm

1 stop12h 00m

Lambert-St Louis

Mon 12/29

4:27 pm-3:55 pm

2 stops46h 28m

$425

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 12/25

4:45 pm-10:00 pm

1 stop6h 15m

Lambert-St Louis

Sun 12/28

10:30 am-9:55 pm

2 stops10h 25m

$441

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 12/25

12:01 pm-7:22 pm

1 stop8h 21m

Lambert-St Louis

Sun 12/28

5:00 am-12:19 pm

1 stop6h 19m

$452

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Greenville to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Greenville to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $298. The month of August is another great option to travel to St. Louis, with average flight prices from Greenville averaging around $316.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Saturday when prices can be found for as low as $321. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $457. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Greenville at noon is the least expensive time of day to depart. momondo users have found prices as low as $358 when looking at flights departing at noon. In the evening is when there is more demand to fly to St. Louis, so prices are often more expensive at around $427 per ticket.

How have Greenville to St. Louis flight prices changed over time?

As of December 2025, prices for Greenville to St. Louis flights are approximately 31% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to St. Louis according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Greenville to St. Louis (GSP to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to St. Louis

Fastest flight time	4h 28m
Direct flights	None

The fastest flight from Greenville to St. Louis takes 4h 28m

There are no direct flights from Greenville to St. Louis. There are no popular flight routes from Greenville to St. Louis.

Search flight deals

How far is Greenville to Lambert-St Louis by plane?
The straight-line distance from Greenville to Lambert-St Louis is 504.1 mi. By plane, this route typically takes 4h 28m.
When did momondo last update prices for flights from Greenville Airport to Lambert-St Louis Airport?
Prices for flights from Greenville Airport to Lambert-St Louis Airport are updated daily.
How many operators does momondo search for flights from Greenville Airport to Lambert-St Louis Airport?
There are 3 operators available for flights from Greenville Airport to Lambert-St Louis Airport as of December 2025.
How old do you have to be to fly from Greenville Airport to Lambert-St Louis Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Lambert-St Louis Airport.
What documentation or ID do you need to fly to Lambert-St Louis Airport?
The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Greenville to St. Louis?
Based on momondo bookings for flights between Greenville and St. Louis, the leading airline is Delta, making up 59% of the total bookings. Other popular airlines include American Airlines with 33% and Southwest with 8%.

Best airlines flying from Greenville to St. Louis

Compare and see reviews for airlines that fly from Greenville to St. Louis with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $236	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights
American Airlines	PriceFrom $286	Free Cancellation	Rating 7.2 11,050 reviews	Search American Airlines flights
Southwest	PriceFrom $288	Free Cancellation	Rating 7.9 4,253 reviews	Search Southwest flights

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O'Fallon

Florissant

Fenton

Wentzville

St. Peters

Collinsville

Alton

Farmington

Festus

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Glencoe

Edwardsville

Eureka

Litchfield

Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to St. Louis with flexible booking policies on momondo?

All flight searches from Greenville to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Greenville to St. Louis?

momondo helps you find the best flight between Greenville and St. Louis by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.