Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Greenville to St. Louis from $152

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to St. Louis departing on 3/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Greenville to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:15 am - 1:17 pm
GSP
-
STL
7h 02m
1 stop
Delta Logo
3:42 pm - 8:17 pm
STL
-
GSP
3h 35m
1 stop
$281Delta
Tue, Jul 7 - Tue, Jul 14
Southwest Logo
5:05 pm - 7:15 pm
GSP
-
STL
3h 10m
1 stop
Southwest Logo
7:35 am - 12:00 pm
STL
-
GSP
3h 25m
1 stop
$295Southwest
Wed, Apr 8 - Mon, Apr 13
Southwest Logo
5:05 pm - 7:15 pm
GSP
-
STL
3h 10m
1 stop
Southwest Logo
2:30 pm - 9:40 pm
STL
-
GSP
6h 10m
1 stop
$298Southwest
Wed, Apr 8 - Tue, Apr 14
Multiple Airlines Logo
10:38 am - 11:19 pm
GSP
-
STL
13h 41m
1 stop
Multiple Airlines Logo
8:23 pm - 1:12 pm
STL
-
GSP
15h 49m
2 stops
$300Multiple Airlines
Thu, Apr 16 - Wed, Apr 22
Southwest Logo
5:05 pm - 7:15 pm
GSP
-
STL
3h 10m
1 stop
Southwest Logo
1:45 pm - 10:15 pm
STL
-
GSP
7h 30m
2 stops
$301Southwest
Wed, Apr 8 - Mon, Apr 13
Southwest Logo
5:05 pm - 10:00 pm
GSP
-
STL
5h 55m
1 stop
Southwest Logo
7:35 am - 12:10 pm
STL
-
GSP
3h 35m
1 stop
$303Southwest
Tue, Apr 21 - Tue, Apr 28
Southwest Logo
5:05 pm - 7:15 pm
GSP
-
STL
3h 10m
1 stop
Southwest Logo
1:15 pm - 9:40 pm
STL
-
GSP
7h 25m
2 stops
$304Southwest
Wed, Apr 8 - Tue, Apr 14
Southwest Logo
5:05 pm - 7:15 pm
GSP
-
STL
3h 10m
1 stop
Southwest Logo
7:35 am - 12:00 pm
STL
-
GSP
3h 25m
1 stop
$306Southwest
Wed, Apr 8 - Mon, Apr 13
Southwest Logo
12:50 pm - 7:55 pm
GSP
-
STL
8h 05m
2 stops
Southwest Logo
1:15 pm - 8:00 pm
STL
-
GSP
5h 45m
1 stop
$308Southwest
Tue, Apr 21 - Tue, Apr 28
Southwest Logo
5:05 pm - 10:10 pm
GSP
-
STL
6h 05m
2 stops
Southwest Logo
1:45 pm - 10:15 pm
STL
-
GSP
7h 30m
2 stops
$310Southwest
Wed, Apr 8 - Mon, Apr 13

United Airlines flights from Greenville to St. Louis

Our best United Airlines deals on Greenville to St. Louis flight tickets
United Airlines
Apr 2
GSP6:30 amGreenville
5h 15m
1 stop
STL10:45 amLambert-St Louis
Apr 9
STL7:45 amLambert-St Louis
10h 14m
2 stops
GSP6:59 pmGreenville
$324
United Airlines
Apr 14
GSP5:41 pmGreenville
4h 32m
1 stop
STL9:13 pmLambert-St Louis
Apr 15
STL6:30 amLambert-St Louis
4h 24m
1 stop
GSP11:54 amGreenville
$373
United Airlines
Mar 31
GSP5:36 pmGreenville
5h 11m
1 stop
STL9:47 pmLambert-St Louis
Apr 8
STL9:10 amLambert-St Louis
12h 35m
2 stops
GSP10:45 pmGreenville
$378

American Airlines flights from Greenville to St. Louis

Our best American Airlines deals on Greenville to St. Louis flight tickets
American Airlines
Mar 31
GSP6:01 amGreenville
5h 58m
1 stop
STL10:59 amLambert-St Louis
Apr 8
STL4:30 pmLambert-St Louis
5h 33m
1 stop
GSP11:03 pmGreenville
$303
American Airlines
Mar 30
GSP12:55 pmGreenville
8h 21m
1 stop
STL8:16 pmLambert-St Louis
Apr 7
STL12:27 pmLambert-St Louis
6h 19m
1 stop
GSP7:46 pmGreenville
$329
American Airlines
Apr 2
GSP6:01 amGreenville
5h 58m
1 stop
STL10:59 amLambert-St Louis
Apr 9
STL5:51 amLambert-St Louis
4h 10m
1 stop
GSP11:01 amGreenville
$339

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 7/7

7:15 am-1:17 pm

1 stop7h 02m

Lambert-St Louis

Tue 7/14

3:42 pm-8:17 pm

1 stop3h 35m

$281
Quickest round-trip

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 4/8

5:05 pm-7:15 pm

1 stop3h 10m

Lambert-St Louis

Mon 4/13

7:35 am-12:00 pm

1 stop3h 25m

$295

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 4/8

5:05 pm-7:15 pm

1 stop3h 10m

Lambert-St Louis

Tue 4/14

2:30 pm-9:40 pm

1 stop6h 10m

$298

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 4/16

10:38 am-11:19 pm

1 stop13h 41m

Lambert-St Louis

Wed 4/22

8:23 pm-1:12 pm

2 stops15h 49m

$300

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 4/8

5:05 pm-7:15 pm

1 stop3h 10m

Lambert-St Louis

Mon 4/13

1:45 pm-10:15 pm

2 stops7h 30m

$301

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 4/21

5:05 pm-10:00 pm

1 stop5h 55m

Lambert-St Louis

Tue 4/28

7:35 am-12:10 pm

1 stop3h 35m

$303

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 4/8

5:05 pm-7:15 pm

1 stop3h 10m

Lambert-St Louis

Tue 4/14

1:15 pm-9:40 pm

2 stops7h 25m

$304

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 4/8

5:05 pm-7:15 pm

1 stop3h 10m

Lambert-St Louis

Mon 4/13

7:35 am-12:00 pm

1 stop3h 25m

$306

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 4/21

12:50 pm-7:55 pm

2 stops8h 05m

Lambert-St Louis

Tue 4/28

1:15 pm-8:00 pm

1 stop5h 45m

$308

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 4/8

5:05 pm-10:10 pm

2 stops6h 05m

Lambert-St Louis

Mon 4/13

1:45 pm-10:15 pm

2 stops7h 30m

$310

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to St. Louis from

How to get the cheapest flight ticket from Greenville to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Greenville to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $298. The month of August is another great option to travel to St. Louis, with average flight prices from Greenville averaging around $316.

How have Greenville to St. Louis flight prices changed over time?

As of March 2026, prices for Greenville to St. Louis flights are approximately 49% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to St. Louis (GSP to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to St. Louis

Fastest flight time

3h 10m

Direct flights

None
The fastest flight from Greenville to St. Louis takes 3h 10m
There are no direct flights from Greenville to St. Louis. There are no popular flight routes from Greenville to St. Louis.
Search flight deals

  • How far is Greenville to Lambert-St Louis by plane?

    The straight-line distance from Greenville to Lambert-St Louis is 504.1 mi. By plane, this route typically takes 3h 10m.

  • When did momondo last update prices for flights from Greenville Airport to Lambert-St Louis Airport?

    Prices for flights from Greenville Airport to Lambert-St Louis Airport are updated daily.

  • How many operators does momondo search for flights from Greenville Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Greenville Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Greenville to St. Louis?

Best airlines flying from Greenville to St. Louis

Compare and see reviews for airlines that fly from Greenville to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $183Free CancellationRating
7.9
8,276 reviews
Search Delta flights
American AirlinesPriceFrom $276Free CancellationRating
7.1
11,414 reviews
Search American Airlines flights
SouthwestPriceFrom $288Free CancellationRating
8.0
4,317 reviews
Search Southwest flights

  • Southwest Flights From Greenville to St. Louis

    Southwest operates around 2 flights from Greenville to St. Louis every week. The average price of these flights found in the last 72 hours has been $367, but momondo users have found Southwest deals from Greenville to St. Louis from as low as $288 round-trip. Southwest has been scored 8.0/10 in 4,317 reviews.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Collinsville
St. Peters
Fenton
Alton
Wentzville
Farmington
Edwardsville
Festus
Clayton
Eureka
Litchfield
Glencoe
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to St. Louis with flexible booking policies on momondo?

All flight searches from Greenville to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Greenville to St. Louis?

momondo helps you find the best flight between Greenville and St. Louis by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 4/9
Thu 4/16
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States