Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Greenville to St. Louis from $196

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:19 pm - 11:56 pmGSP  Greenville-STL Lambert-St Louis
5h 37m1 stop Atlanta Hartsfield-Jackson
Delta Logo
3:15 pm - 10:12 pmSTL  Lambert-St Louis-GSP Greenville
5h 57m1 stop Atlanta Hartsfield-Jackson
$233Delta
Thu, Nov 19 - Thu, Nov 26
Southwest Logo
6:45 pm - 10:00 pmGSP  Greenville-STL Lambert-St Louis
4h 15m1 stop Nashville Intl
Southwest Logo
7:45 am - 4:10 pmSTL  Lambert-St Louis-GSP Greenville
7h 25m2 stops Austin Bergstrom Nashville Intl
$238Southwest
Thu, Nov 19 - Thu, Nov 26
Southwest Logo
7:05 am - 1:45 pmGSP  Greenville-STL Lambert-St Louis
7h 40m2 stops Nashville Intl Atlanta Hartsfield-Jackson
Southwest Logo
5:40 am - 12:25 pmSTL  Lambert-St Louis-GSP Greenville
5h 45m2 stops Chicago Midway Nashville Intl
$243Southwest
Thu, Nov 19 - Thu, Nov 26
Southwest Logo
6:40 am - 10:40 amGSP  Greenville-STL Lambert-St Louis
5h 00m1 stop Nashville Intl
Southwest Logo
1:45 pm - 8:20 pmSTL  Lambert-St Louis-GSP Greenville
5h 35m1 stop Baltimore/Washington
$263Southwest
Fri, Feb 5 - Mon, Feb 8
Delta Logo
7:19 pm - 11:56 pmGSP  Greenville-STL Lambert-St Louis
5h 37m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 1:15 pmSTL  Lambert-St Louis-GSP Greenville
6h 15m1 stop Atlanta Hartsfield-Jackson
$312Delta
Mon, Nov 16 - Thu, Nov 19
American Airlines Logo
5:17 pm - 11:34 pmGSP  Greenville-STL Lambert-St Louis
7h 17m1 stop Dallas/Fort Worth
American Airlines Logo
6:57 am - 2:48 pmSTL  Lambert-St Louis-GSP Greenville
6h 51m1 stop Washington, D.C. Reagan-National
$325American Airlines
Fri, Dec 11 - Sun, Dec 20
American Airlines Logo
5:17 pm - 11:34 pmGSP  Greenville-STL Lambert-St Louis
7h 17m1 stop Dallas/Fort Worth
American Airlines Logo
6:57 am - 2:48 pmSTL  Lambert-St Louis-GSP Greenville
6h 51m1 stop Washington, D.C. Reagan-National
$328American Airlines
Fri, Dec 11 - Sun, Dec 20
Delta Logo
5:38 am - 11:04 amGSP  Greenville-STL Lambert-St Louis
6h 26m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:07 am - 2:22 pmSTL  Lambert-St Louis-GSP Greenville
6h 15m1 stop Atlanta Hartsfield-Jackson
$328Delta
Thu, Feb 4 - Sun, Feb 7
United Airlines Logo
6:30 am - 12:13 pmGSP  Greenville-STL Lambert-St Louis
6h 43m1 stop Chicago O'Hare Intl
United Airlines Logo
1:17 pm - 11:34 pmSTL  Lambert-St Louis-GSP Greenville
9h 17m2 stops Chicago O'Hare Intl Newark
$433United Airlines
Thu, Feb 4 - Sun, Feb 7
United Airlines Logo
10:42 am - 3:43 pmGSP  Greenville-STL Lambert-St Louis
6h 01m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 1:30 pmSTL  Lambert-St Louis-GSP Greenville
6h 30m1 stop Chicago O'Hare Intl
$444United Airlines
Mon, Nov 23 - Fri, Nov 27

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Greenville to St. Louis

Our best American Airlines deals on Greenville to St. Louis flight tickets
American Airlines
Dec 11
GSP5:17 pmGreenville
7h 17m
1 stop
STL11:34 pmLambert-St Louis
Dec 20
STL6:57 amLambert-St Louis
6h 51m
1 stop
GSP2:48 pmGreenville
$325
American Airlines
Dec 11
GSP5:17 pmGreenville
7h 17m
1 stop
STL11:34 pmLambert-St Louis
Dec 20
STL6:57 amLambert-St Louis
6h 51m
1 stop
GSP2:48 pmGreenville
$328
American Airlines
Dec 11
GSP5:17 pmGreenville
7h 17m
1 stop
STL11:34 pmLambert-St Louis
Dec 20
STL6:57 amLambert-St Louis
6h 51m
1 stop
GSP2:48 pmGreenville
$351

Southwest flights from Greenville to St. Louis

Our best Southwest deals on Greenville to St. Louis flight tickets
Southwest
Nov 19
GSP6:45 pmGreenville
4h 15m
1 stop
STL10:00 pmLambert-St Louis
Nov 26
STL7:45 amLambert-St Louis
7h 25m
2 stops
GSP4:10 pmGreenville
$238
Southwest
Nov 19
GSP7:05 amGreenville
7h 40m
2 stops
STL1:45 pmLambert-St Louis
Nov 26
STL5:40 amLambert-St Louis
5h 45m
2 stops
GSP12:25 pmGreenville
$243
Southwest
Feb 4
GSP11:10 amGreenville
3h 40m
1 stop
STL1:50 pmLambert-St Louis
Feb 7
STL12:30 pmLambert-St Louis
3h 00m
1 stop
GSP4:30 pmGreenville
$263

momondo Fare Finder

 
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 11/19

7:19 pm-11:56 pm

1 stop5h 37m

Lambert-St Louis

Thu 11/26

3:15 pm-10:12 pm

1 stop5h 57m

$233

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 11/19

6:45 pm-10:00 pm

1 stop4h 15m

Lambert-St Louis

Thu 11/26

7:45 am-4:10 pm

2 stops7h 25m

$238

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 11/19

7:05 am-1:45 pm

2 stops7h 40m

Lambert-St Louis

Thu 11/26

5:40 am-12:25 pm

2 stops5h 45m

$243
Quickest round-trip

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Fri 2/5

6:40 am-10:40 am

1 stop5h 00m

Lambert-St Louis

Mon 2/8

1:45 pm-8:20 pm

1 stop5h 35m

$263

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Mon 11/16

7:19 pm-11:56 pm

1 stop5h 37m

Lambert-St Louis

Thu 11/19

6:00 am-1:15 pm

1 stop6h 15m

$312

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Fri 12/11

5:17 pm-11:34 pm

1 stop7h 17m

Lambert-St Louis

Sun 12/20

6:57 am-2:48 pm

1 stop6h 51m

$325

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Fri 12/11

5:17 pm-11:34 pm

1 stop7h 17m

Lambert-St Louis

Sun 12/20

6:57 am-2:48 pm

1 stop6h 51m

$328

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 2/4

5:38 am-11:04 am

1 stop6h 26m

Lambert-St Louis

Sun 2/7

7:07 am-2:22 pm

1 stop6h 15m

$328

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 2/4

6:30 am-12:13 pm

1 stop6h 43m

Lambert-St Louis

Sun 2/7

1:17 pm-11:34 pm

2 stops9h 17m

$433

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Mon 11/23

10:42 am-3:43 pm

1 stop6h 01m

Lambert-St Louis

Fri 11/27

6:00 am-1:30 pm

1 stop6h 30m

$444

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to St. Louis from

How to get the cheapest flight ticket from Greenville to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and St. Louis?

Prices are currently low for flights on this route.

Typical prices usually range from $384 to $672.
The lowest price recently found on this route was $233.

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Greenville to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $346. The month of June is another great option to travel to St. Louis, with average flight prices from Greenville averaging around $358.

How have Greenville to St. Louis flight prices changed over time?

As of October 2026, prices for Greenville to St. Louis flights are approximately 136% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to St. Louis (GSP to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to St. Louis

Best Price Found

$196

Fastest flight time

4h 15m

Direct flights

None
The best one-way flight to St. Louis from Greenville in the past 72 hours is $196. The best round-trip flight deal from Greenville to St. Louis found on momondo in the last 72 hours is $233.
The fastest flight from Greenville to St. Louis takes 4h 15m
There are no direct flights from Greenville to St. Louis. There are no popular flight routes from Greenville to St. Louis.
Search flight deals

Frequently asked questions about flying from Greenville to St. Louis

  • How far is Greenville to Lambert-St Louis by plane?

    The straight-line distance from Greenville to Lambert-St Louis is 504.1 mi. By plane, this route typically takes 4h 15m.

  • When did momondo last update prices for flights from Greenville Airport to Lambert-St Louis Airport?

    Prices for flights from Greenville Airport to Lambert-St Louis Airport are updated daily.

  • How many operators does momondo search for flights from Greenville Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Greenville Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Greenville to St. Louis?

Best airlines flying from Greenville to St. Louis

Compare and see reviews for airlines that fly from Greenville to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $246Free CancellationRating
7.8
8,682 reviews
Search Delta flights
SouthwestPriceFrom $258Free CancellationRating
7.9
4,220 reviews
Search Southwest flights
American AirlinesPriceFrom $268Free CancellationRating
7.0
12,194 reviews
Search American Airlines flights

  • Southwest Flights From Greenville to St. Louis

    Southwest operates around 3 flights from Greenville to St. Louis every week. The average price of these flights found in the last 72 hours has been $396, but momondo users have found Southwest deals from Greenville to St. Louis from as low as $258 round-trip. Southwest has been scored 7.9/10 in 4,220 reviews.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Maryland Heights
St. Peters
Alton
Collinsville
Florissant
Farmington
Hermann
Festus
Clayton
Fenton
Edwardsville
O'Fallon
Eureka
Wentzville
Litchfield
Grafton
Waterloo

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to St. Louis with flexible booking policies on momondo?

All flight searches from Greenville to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Greenville to St. Louis?

momondo helps you find the best flight between Greenville and St. Louis by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 11/27
Fri 12/4
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States