Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Greenville to St. Louis from $193

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:41 pm - 10:42 pmGSP  Greenville-STL Lambert-St Louis
4h 01m1 stop Charlotte Douglas
American Airlines Logo
10:48 am - 4:23 pmSTL  Lambert-St Louis-GSP Greenville
4h 35m1 stop Washington, D.C. Reagan-National
$259American Airlines
Sat, Oct 3 - Tue, Oct 6
American Airlines Logo
4:49 pm - 9:24 pmGSP  Greenville-STL Lambert-St Louis
5h 35m1 stop Washington, D.C. Reagan-National
American Airlines Logo
3:34 pm - 10:11 pmSTL  Lambert-St Louis-GSP Greenville
5h 37m1 stop Dallas/Fort Worth
$259American Airlines
Wed, Sep 30 - Sat, Oct 3
Southwest Logo
8:40 pm - 11:35 pmGSP  Greenville-STL Lambert-St Louis
3h 55m1 stop Nashville Intl
Southwest Logo
5:50 pm - 10:50 pmSTL  Lambert-St Louis-GSP Greenville
4h 00m1 stop Nashville Intl
$259Southwest
Thu, Oct 1 - Mon, Oct 5
Southwest Logo
8:40 pm - 11:35 pmGSP  Greenville-STL Lambert-St Louis
3h 55m1 stop Nashville Intl
Southwest Logo
8:10 am - 12:40 pmSTL  Lambert-St Louis-GSP Greenville
3h 30m1 stop Nashville Intl
$259Southwest
Thu, Oct 1 - Wed, Oct 7
United Airlines Logo
6:20 am - 12:13 pmGSP  Greenville-STL Lambert-St Louis
6h 53m1 stop Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 9:17 pmSTL  Lambert-St Louis-GSP Greenville
5h 06m1 stop Chicago O'Hare Intl
$259United Airlines
Thu, Oct 1 - Mon, Oct 5
American Airlines Logo
4:37 pm - 10:15 pmGSP  Greenville-STL Lambert-St Louis
6h 38m1 stop Chicago O'Hare Intl
American Airlines Logo
11:23 am - 6:06 pmSTL  Lambert-St Louis-GSP Greenville
5h 43m1 stop Chicago O'Hare Intl
$259American Airlines
Wed, Nov 4 - Sat, Nov 7
Southwest Logo
8:40 pm - 11:40 pmGSP  Greenville-STL Lambert-St Louis
4h 00m1 stop Nashville Intl
Southwest Logo
4:30 pm - 9:05 pmSTL  Lambert-St Louis-GSP Greenville
3h 35m1 stop Nashville Intl
$259Southwest
Mon, Oct 5 - Tue, Oct 6
Delta Logo
5:40 am - 10:51 amGSP  Greenville-STL Lambert-St Louis
6h 11m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:35 pm - 10:51 pmSTL  Lambert-St Louis-GSP Greenville
4h 16m1 stop Atlanta Hartsfield-Jackson
$277Delta
Thu, Oct 8 - Thu, Oct 15
United Airlines Logo
10:26 am - 6:09 pmGSP  Greenville-STL Lambert-St Louis
8h 43m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
11:15 am - 4:56 pmSTL  Lambert-St Louis-GSP Greenville
4h 41m1 stop Chicago O'Hare Intl
$279United Airlines
Thu, Oct 29 - Sat, Nov 7
Delta Logo
8:06 am - 11:29 amGSP  Greenville-STL Lambert-St Louis
4h 23m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:01 am - 11:59 amSTL  Lambert-St Louis-GSP Greenville
3h 58m1 stop Atlanta Hartsfield-Jackson
$490Delta
Fri, Dec 18 - Sat, Dec 26

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Southwest flights from Greenville to St. Louis

Our best Southwest deals on Greenville to St. Louis flight tickets
Southwest
Oct 1
GSP8:40 pmGreenville
3h 55m
1 stop
STL11:35 pmLambert-St Louis
Oct 7
STL8:10 amLambert-St Louis
3h 30m
1 stop
GSP12:40 pmGreenville
$259
Southwest
Oct 5
GSP8:40 pmGreenville
4h 00m
1 stop
STL11:40 pmLambert-St Louis
Oct 7
STL11:25 amLambert-St Louis
7h 40m
1 stop
GSP8:05 pmGreenville
$264
Southwest
Oct 1
GSP8:40 pmGreenville
3h 55m
1 stop
STL11:35 pmLambert-St Louis
Oct 7
STL8:30 amLambert-St Louis
10h 35m
2 stops
GSP8:05 pmGreenville
$270

United Airlines flights from Greenville to St. Louis

Our best United Airlines deals on Greenville to St. Louis flight tickets
United Airlines
Oct 29
GSP10:26 amGreenville
8h 43m
2 stops
STL6:09 pmLambert-St Louis
Nov 7
STL11:15 amLambert-St Louis
4h 41m
1 stop
GSP4:56 pmGreenville
$279
United Airlines
Sep 30
GSP5:46 pmGreenville
6h 13m
1 stop
STL10:59 pmLambert-St Louis
Oct 3
STL8:00 amLambert-St Louis
10h 00m
2 stops
GSP7:00 pmGreenville
$344
United Airlines
Oct 29
GSP6:20 amGreenville
5h 12m
1 stop
STL10:32 amLambert-St Louis
Oct 30
STL1:00 pmLambert-St Louis
9h 00m
2 stops
GSP11:00 pmGreenville
$362

momondo Fare Finder

 
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Sat 10/3

7:41 pm-10:42 pm

1 stop4h 01m

Lambert-St Louis

Tue 10/6

10:48 am-4:23 pm

1 stop4h 35m

$259

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Wed 9/30

4:49 pm-9:24 pm

1 stop5h 35m

Lambert-St Louis

Sat 10/3

3:34 pm-10:11 pm

1 stop5h 37m

$259

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 10/1

8:40 pm-11:35 pm

1 stop3h 55m

Lambert-St Louis

Mon 10/5

5:50 pm-10:50 pm

1 stop4h 00m

$259
Quickest round-trip

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 10/1

8:40 pm-11:35 pm

1 stop3h 55m

Lambert-St Louis

Wed 10/7

8:10 am-12:40 pm

1 stop3h 30m

$259

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 10/1

6:20 am-12:13 pm

1 stop6h 53m

Lambert-St Louis

Mon 10/5

3:11 pm-9:17 pm

1 stop5h 06m

$259

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Wed 11/4

4:37 pm-10:15 pm

1 stop6h 38m

Lambert-St Louis

Sat 11/7

11:23 am-6:06 pm

1 stop5h 43m

$259

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Mon 10/5

8:40 pm-11:40 pm

1 stop4h 00m

Lambert-St Louis

Tue 10/6

4:30 pm-9:05 pm

1 stop3h 35m

$259

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 10/8

5:40 am-10:51 am

1 stop6h 11m

Lambert-St Louis

Thu 10/15

5:35 pm-10:51 pm

1 stop4h 16m

$277

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Thu 10/29

10:26 am-6:09 pm

2 stops8h 43m

Lambert-St Louis

Sat 11/7

11:15 am-4:56 pm

1 stop4h 41m

$279

GreenvilleSt. Louis

GSP Greenville - STL Lambert-St Louis

GSPSTL

Greenville

Fri 12/18

8:06 am-11:29 am

1 stop4h 23m

Lambert-St Louis

Sat 12/26

7:01 am-11:59 am

1 stop3h 58m

$490

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to St. Louis from

How to get the cheapest flight ticket from Greenville to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and St. Louis?

Prices are currently low for flights on this route.

Typical prices usually range from $386 to $546.
The lowest price recently found on this route was $259.

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Greenville to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $286. The month of June is another great option to travel to St. Louis, with average flight prices from Greenville averaging around $358.

How have Greenville to St. Louis flight prices changed over time?

As of September 2026, prices for Greenville to St. Louis flights are approximately 15% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to St. Louis (GSP to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to St. Louis

Best Price Found

$193

Fastest flight time

3h 55m

Direct flights

None
The best one-way flight to St. Louis from Greenville in the past 72 hours is $193. The best round-trip flight deal from Greenville to St. Louis found on momondo in the last 72 hours is $259.
The fastest flight from Greenville to St. Louis takes 3h 55m
There are no direct flights from Greenville to St. Louis. There are no popular flight routes from Greenville to St. Louis.
Search flight deals

Frequently asked questions about flying from Greenville to St. Louis

  • How far is Greenville to Lambert-St Louis by plane?

    The straight-line distance from Greenville to Lambert-St Louis is 504.1 mi. By plane, this route typically takes 3h 55m.

  • When did momondo last update prices for flights from Greenville Airport to Lambert-St Louis Airport?

    Prices for flights from Greenville Airport to Lambert-St Louis Airport are updated daily.

  • How many operators does momondo search for flights from Greenville Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Greenville Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Greenville to St. Louis?

Best airlines flying from Greenville to St. Louis

Compare and see reviews for airlines that fly from Greenville to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $246Free CancellationRating
7.8
8,568 reviews
Search Delta flights
American AirlinesPriceFrom $268Free CancellationRating
7.1
12,050 reviews
Search American Airlines flights
SouthwestPriceFrom $288Free CancellationRating
8.0
4,191 reviews
Search Southwest flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
St. Peters
Maryland Heights
Alton
Collinsville
Florissant
Hermann
Clayton
O'Fallon
Farmington
Fenton
Festus
Edwardsville
Wentzville
Eureka
Litchfield
Grafton
Waterloo

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to St. Louis with flexible booking policies on momondo?

All flight searches from Greenville to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Greenville to St. Louis?

momondo helps you find the best flight between Greenville and St. Louis by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 10/13
Tue 10/20
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States