Cheap flights from Florence, South Carolina to St. Louis from $696

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to St. Louis departing on 8/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Florence, South Carolina to St. Louis (FLO-STL)

Cheap round-trip flights

American Airlines Logo
11:15 am - 8:18 pmFLO-STL
10h 03m2 stops
American Airlines Logo
9:27 am - 11:16 pmSTL-FLO
12h 49m2 stops
$696American Airlines
Find Deal
Sun, Aug 31 - Thu, Sep 4
American Airlines Logo
11:15 am - 8:18 pmFLO-STL
10h 03m2 stops
American Airlines Logo
9:57 am - 5:12 pmSTL-FLO
6h 15m1 stop
$799American Airlines
Find Deal
Sun, Aug 31 - Thu, Sep 4
American Airlines Logo
9:05 am - 12:11 pmFLO-STL
4h 06m1 stop
American Airlines Logo
9:57 am - 5:12 pmSTL-FLO
6h 15m1 stop
$835American Airlines
Find Deal
Sun, Aug 31 - Thu, Sep 4

American Airlines flights from Florence, South Carolina to St. Louis

Our best American Airlines deals on Florence, South Carolina to St. Louis flight tickets
American Airlines
Aug 31
FLO11:15 amFlorence
10h 03m
2 stops
STL8:18 pmLambert-St Louis
Sep 4
STL9:27 amLambert-St Louis
12h 49m
2 stops
FLO11:16 pmFlorence
American Airlines
Aug 31
FLO11:15 amFlorence
10h 03m
2 stops
STL8:18 pmLambert-St Louis
Sep 4
STL9:57 amLambert-St Louis
6h 15m
1 stop
FLO5:12 pmFlorence
American Airlines
Aug 31
FLO9:05 amFlorence
4h 06m
1 stop
STL12:11 pmLambert-St Louis
Sep 4
STL9:57 amLambert-St Louis
6h 15m
1 stop
FLO5:12 pmFlorence

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 17, 2025.
Use the filters below to find and compare flights from Florence, South Carolina to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Sun 8/31

11:15 am-8:18 pm

2 stops10h 03m

Lambert-St Louis

Thu 9/4

9:27 am-11:16 pm

2 stops12h 49m

$696

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Sun 8/31

11:15 am-8:18 pm

2 stops10h 03m

Lambert-St Louis

Thu 9/4

9:57 am-5:12 pm

1 stop6h 15m

$799

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Sun 8/31

9:05 am-12:11 pm

1 stop4h 06m

Lambert-St Louis

Thu 9/4

9:57 am-5:12 pm

1 stop6h 15m

$835

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to St. Louis from

How to get the cheapest flight ticket from Florence, South Carolina to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to St. Louis?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to St. Louis from Florence, South Carolina according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 5 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

When to book flights from Florence, South Carolina to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Florence, South Carolina to St. Louis (FLO to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to St. Louis

Best Price Found

$696

Fastest flight time

4h 06m

Direct flights

None

Airports in St. Louis

1 airport
The best flight deal from Florence, South Carolina to St. Louis found on momondo in the last 72 hours is $696
The fastest flight from Florence, South Carolina to St. Louis takes 4h 06m
There are no direct flights from Florence, South Carolina to St. Louis. Popular non-direct route for this connection is Florence Airport - Lambert-St Louis Airport.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
  • How far is Florence to Lambert-St Louis by plane?

    The distance between Florence and Lambert-St Louis is about 655.0 mi. In terms of flight time, this usually takes a little over 4h 06m.

  • When did momondo last update prices for flights from Florence Airport to Lambert-St Louis Airport?

    Prices for flights from Florence Airport to Lambert-St Louis Airport were last updated today.

  • How old do you have to be to fly from Florence Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florence Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
Maryland Heights
Florissant
O'Fallon
Fenton
Wentzville
Collinsville
Alton
St. Peters
Farmington
Festus
Glencoe
Eureka
Clayton
Edwardsville
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Florence to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Florence to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Florence to St. Louis with flexible booking policies on momondo?

Yes. All flights to St. Louis from Florence on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Florence to St. Louis?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Florence to St. Louis.

I’m not ready to book a flight from Florence to St. Louis right now. Can momondo alert me if prices change?

If you are simply researching potential flights to St. Louis, momondo offers a useful price alert feature which will track prices for flights to St. Louis from Florence and alert you when they change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 8/22
Fri 8/29

Find better results for your trip to the United States