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Cheap flights from Detroit to Panama City from $130

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 8/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Southwest Logo
6:15 am - 9:05 amDTW-ECP
3h 50m1 stop
Southwest Logo
3:00 pm - 8:00 pmECP-DTW
4h 00m1 stop
$218Southwest
Find Deal
Wed, Aug 27 - Sat, Aug 30
American Airlines Logo
9:42 am - 5:30 pmDTW-ECP
8h 48m2 stops
American Airlines Logo
5:30 am - 11:04 amECP-DTW
4h 34m1 stop
$223American Airlines
Find Deal
Wed, Aug 27 - Sun, Aug 31
American Airlines Logo
4:00 pm - 10:09 pmDTW-ECP
7h 09m2 stops
American Airlines Logo
5:30 am - 3:19 pmECP-DTW
8h 49m2 stops
$228American Airlines
Find Deal
Wed, Aug 27 - Sat, Aug 30
American Airlines Logo
12:08 pm - 7:32 pmDTW-ECP
8h 24m1 stop
American Airlines Logo
11:28 am - 8:46 pmECP-DTW
8h 18m1 stop
$233American Airlines
Find Deal
Sat, Oct 18 - Fri, Oct 31
Delta Logo
7:59 pm - 11:03 pmDTW-ECP
4h 04m1 stop
Delta Logo
5:32 pm - 12:41 amECP-DTW
6h 09m1 stop
$237Delta
Find Deal
Sat, Oct 4 - Wed, Oct 8
American Airlines Logo
6:45 am - 5:36 pmDTW-ECP
11h 51m2 stops
American Airlines Logo
6:06 pm - 11:22 pmECP-DTW
4h 16m1 stop
$242American Airlines
Find Deal
Sat, Sep 20 - Mon, Sep 22
Delta Logo
7:59 pm - 11:03 pmDTW-ECP
4h 04m1 stop
Delta Logo
6:00 am - 11:10 amECP-DTW
4h 10m1 stop
$248Delta
Find Deal
Fri, Oct 3 - Tue, Oct 7
Southwest Logo
6:15 am - 9:05 amDTW-ECP
3h 50m1 stop
Southwest Logo
1:35 pm - 9:50 pmECP-DTW
7h 15m1 stop
$259Southwest
Find Deal
Wed, Aug 13 - Mon, Aug 18
United Airlines Logo
7:00 am - 1:03 pmDTW-ECP
7h 03m1 stop
United Airlines Logo
11:10 am - 11:41 pmECP-DTW
11h 31m2 stops
$266United Airlines
Find Deal
Wed, Sep 24 - Sat, Sep 27
United Airlines Logo
6:00 am - 4:20 pmDTW-ECP
11h 20m2 stops
United Airlines Logo
6:30 am - 6:50 pmECP-DTW
11h 20m2 stops
$317United Airlines
Find Deal
Sat, Sep 20 - Mon, Sep 22

Delta flights from Detroit to Panama City, Florida

Our best Delta deals on Detroit to Panama City, Florida flight tickets
Delta
Oct 4
DTW7:59 pmDetroit Metropolitan Wayne County
4h 04m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Oct 8
ECP5:32 pmPanama City NW Florida Beaches
6h 09m
1 stop
DTW12:41 amDetroit Metropolitan Wayne County
$237
Find similar
Delta
Oct 3
DTW7:59 pmDetroit Metropolitan Wayne County
4h 04m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Oct 7
ECP6:00 amPanama City NW Florida Beaches
4h 10m
1 stop
DTW11:10 amDetroit Metropolitan Wayne County
$248
Find similar
Delta
Aug 4
DTW8:50 amDetroit Metropolitan Wayne County
6h 51m
1 stop
ECP2:41 pmPanama City NW Florida Beaches
Aug 18
ECP6:00 amPanama City NW Florida Beaches
4h 09m
1 stop
DTW11:09 amDetroit Metropolitan Wayne County
$259
Find similar

American Airlines flights from Detroit to Panama City, Florida

Our best American Airlines deals on Detroit to Panama City, Florida flight tickets
American Airlines
Aug 27
DTW9:42 amDetroit Metropolitan Wayne County
8h 48m
2 stops
ECP5:30 pmPanama City NW Florida Beaches
Aug 31
ECP5:30 amPanama City NW Florida Beaches
4h 34m
1 stop
DTW11:04 amDetroit Metropolitan Wayne County
$223
Find similar
American Airlines
Aug 27
DTW4:00 pmDetroit Metropolitan Wayne County
7h 09m
2 stops
ECP10:09 pmPanama City NW Florida Beaches
Aug 30
ECP5:30 amPanama City NW Florida Beaches
8h 49m
2 stops
DTW3:19 pmDetroit Metropolitan Wayne County
$228
Find similar
American Airlines
Oct 18
DTW12:08 pmDetroit Metropolitan Wayne County
8h 24m
1 stop
ECP7:32 pmPanama City NW Florida Beaches
Oct 31
ECP11:28 amPanama City NW Florida Beaches
8h 18m
1 stop
DTW8:46 pmDetroit Metropolitan Wayne County
$233
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momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Detroit to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 8/27

6:15 am-9:05 am

1 stop3h 50m

Panama City NW Florida Beaches

Sat 8/30

3:00 pm-8:00 pm

1 stop4h 00m

$218

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 8/27

9:42 am-5:30 pm

2 stops8h 48m

Panama City NW Florida Beaches

Sun 8/31

5:30 am-11:04 am

1 stop4h 34m

$223

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 8/27

4:00 pm-10:09 pm

2 stops7h 09m

Panama City NW Florida Beaches

Sat 8/30

5:30 am-3:19 pm

2 stops8h 49m

$228

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 10/18

12:08 pm-7:32 pm

1 stop8h 24m

Panama City NW Florida Beaches

Fri 10/31

11:28 am-8:46 pm

1 stop8h 18m

$233

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 10/4

7:59 pm-11:03 pm

1 stop4h 04m

Panama City NW Florida Beaches

Wed 10/8

5:32 pm-12:41 am

1 stop6h 09m

$237

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 9/20

6:45 am-5:36 pm

2 stops11h 51m

Panama City NW Florida Beaches

Mon 9/22

6:06 pm-11:22 pm

1 stop4h 16m

$242

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 10/3

7:59 pm-11:03 pm

1 stop4h 04m

Panama City NW Florida Beaches

Tue 10/7

6:00 am-11:10 am

1 stop4h 10m

$248

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 8/13

6:15 am-9:05 am

1 stop3h 50m

Panama City NW Florida Beaches

Mon 8/18

1:35 pm-9:50 pm

1 stop7h 15m

$259

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 9/24

7:00 am-1:03 pm

1 stop7h 03m

Panama City NW Florida Beaches

Sat 9/27

11:10 am-11:41 pm

2 stops11h 31m

$266

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 9/20

6:00 am-4:20 pm

2 stops11h 20m

Panama City NW Florida Beaches

Mon 9/22

6:30 am-6:50 pm

2 stops11h 20m

$317

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit is in September. Flight prices, which tend to average around $256, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Panama City, Florida, with average flight prices from Detroit averaging around $298.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $309. On the other hand, Friday is the most expensive day to depart from Detroit because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $436.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $367 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit for as low as $332 on momondo.

When to book flights from Detroit to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City, Florida (DTT to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City, Florida

Best Price Found

$130

Fastest flight time

3h 47m

Direct flights

None

Airports in Panama City, Florida

1 airport
The best one-way flight to Panama City, Florida from Detroit in the past 72 hours is $130. The best round-trip flight deal from Detroit to Panama City, Florida found on momondo in the last 72 hours is $218.
The fastest flight from Detroit to Panama City, Florida takes 3h 47m
There are no direct flights from Detroit to Panama City, Florida. Popular non-direct route for this connection is Detroit Metropolitan Wayne County Airport - Panama City NW Florida Beaches Airport.
There is 1 airport near Panama City, Florida: Panama City NW Florida Beaches (ECP)
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  • How far is Detroit to Panama City NW Florida Beaches by plane?

    A flight from Detroit to Panama City NW Florida Beaches will travel around 853.2 mi. By plane, this route typically takes 3h 47m.

  • When did momondo last update prices for flights from Detroit to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Detroit to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Panama City, Florida?

Best airlines flying from Detroit to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $227Free CancellationRating
8.0
7,983 reviews
Search Delta flights
SouthwestPriceFrom $258Free CancellationRating
8.0
4,246 reviews
Search Southwest flights
American AirlinesPriceFrom $267Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama City?

Once all potential Detroit to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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