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Cheap flights from Detroit to Panama City from $101

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 8/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:43 pm - 10:40 pm
DTW
-
ECP
4h 57m
1 stop
American Airlines Logo
5:48 pm - 11:32 pm
ECP
-
DTW
4h 44m
1 stop
$201American Airlines
Thu, Aug 20 - Mon, Aug 24
Southwest Logo
6:00 am - 9:40 am
DTW
-
ECP
4h 40m
1 stop
Southwest Logo
4:10 pm - 10:35 pm
ECP
-
DTW
5h 25m
1 stop
$211Southwest
Tue, Aug 11 - Thu, Aug 13
Southwest Logo
12:55 pm - 6:10 pm
DTW
-
ECP
6h 15m
2 stops
Southwest Logo
7:15 am - 12:45 pm
ECP
-
DTW
4h 30m
1 stop
$216Southwest
Tue, Aug 18 - Sat, Aug 22
Southwest Logo
6:25 am - 3:00 pm
DTW
-
ECP
9h 35m
2 stops
Southwest Logo
10:30 am - 5:40 pm
ECP
-
DTW
6h 10m
2 stops
$222Southwest
Tue, Aug 18 - Sat, Aug 22
American Airlines Logo
6:43 pm - 10:40 pm
DTW
-
ECP
4h 57m
1 stop
American Airlines Logo
6:40 am - 2:10 pm
ECP
-
DTW
6h 30m
1 stop
$226American Airlines
Fri, Aug 21 - Tue, Aug 25
American Airlines Logo
6:43 pm - 10:40 pm
DTW
-
ECP
4h 57m
1 stop
American Airlines Logo
6:40 am - 2:10 pm
ECP
-
DTW
6h 30m
1 stop
$227American Airlines
Fri, Aug 21 - Tue, Aug 25
Southwest Logo
6:25 am - 3:40 pm
DTW
-
ECP
10h 15m
1 stop
Southwest Logo
10:40 am - 5:40 pm
ECP
-
DTW
6h 00m
2 stops
$231Southwest
Wed, Sep 9 - Sat, Sep 12
American Airlines Logo
6:43 pm - 10:40 pm
DTW
-
ECP
4h 57m
1 stop
American Airlines Logo
5:48 pm - 11:32 pm
ECP
-
DTW
4h 44m
1 stop
$232American Airlines
Thu, Aug 20 - Mon, Aug 24
Southwest Logo
6:25 am - 3:40 pm
DTW
-
ECP
10h 15m
1 stop
Southwest Logo
7:15 am - 12:45 pm
ECP
-
DTW
4h 30m
1 stop
$233Southwest
Wed, Sep 16 - Sat, Sep 19
Southwest Logo
8:45 am - 3:40 pm
DTW
-
ECP
7h 55m
2 stops
Southwest Logo
10:30 am - 5:40 pm
ECP
-
DTW
6h 10m
2 stops
$238Southwest
Wed, Sep 16 - Sat, Sep 19

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United Airlines flights from Detroit to Panama City, Florida

Our best United Airlines deals on Detroit to Panama City, Florida flight tickets
United Airlines
Aug 5
DTW8:50 amDetroit Metropolitan Wayne County
5h 34m
1 stop
ECP1:24 pmPanama City NW Florida Beaches
Aug 12
ECP11:41 amPanama City NW Florida Beaches
11h 15m
2 stops
DTW11:56 pmDetroit Metropolitan Wayne County
$307
United Airlines
Aug 11
DTW7:34 amDetroit Metropolitan Wayne County
6h 32m
1 stop
ECP1:06 pmPanama City NW Florida Beaches
Aug 13
ECP1:47 pmPanama City NW Florida Beaches
5h 42m
1 stop
DTW8:29 pmDetroit Metropolitan Wayne County
$311
United Airlines
Aug 11
DTW5:25 amDetroit Metropolitan Wayne County
12h 13m
2 stops
ECP4:38 pmPanama City NW Florida Beaches
Aug 13
ECP1:47 pmPanama City NW Florida Beaches
5h 42m
1 stop
DTW8:29 pmDetroit Metropolitan Wayne County
$316

American Airlines flights from Detroit to Panama City, Florida

Our best American Airlines deals on Detroit to Panama City, Florida flight tickets
American Airlines
Aug 20
DTW6:43 pmDetroit Metropolitan Wayne County
4h 57m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Aug 24
ECP5:48 pmPanama City NW Florida Beaches
4h 44m
1 stop
DTW11:32 pmDetroit Metropolitan Wayne County
$201
American Airlines
Aug 21
DTW6:43 pmDetroit Metropolitan Wayne County
4h 57m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Aug 25
ECP6:40 amPanama City NW Florida Beaches
6h 30m
1 stop
DTW2:10 pmDetroit Metropolitan Wayne County
$226
American Airlines
Aug 21
DTW6:43 pmDetroit Metropolitan Wayne County
4h 57m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Aug 25
ECP6:40 amPanama City NW Florida Beaches
6h 30m
1 stop
DTW2:10 pmDetroit Metropolitan Wayne County
$227

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Detroit to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Thu 8/20

6:43 pm-10:40 pm

1 stop4h 57m

Panama City NW Florida Beaches

Mon 8/24

5:48 pm-11:32 pm

1 stop4h 44m

$201

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 8/11

6:00 am-9:40 am

1 stop4h 40m

Panama City NW Florida Beaches

Thu 8/13

4:10 pm-10:35 pm

1 stop5h 25m

$211

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 8/18

12:55 pm-6:10 pm

2 stops6h 15m

Panama City NW Florida Beaches

Sat 8/22

7:15 am-12:45 pm

1 stop4h 30m

$216

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 8/18

6:25 am-3:00 pm

2 stops9h 35m

Panama City NW Florida Beaches

Sat 8/22

10:30 am-5:40 pm

2 stops6h 10m

$222

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 8/21

6:43 pm-10:40 pm

1 stop4h 57m

Panama City NW Florida Beaches

Tue 8/25

6:40 am-2:10 pm

1 stop6h 30m

$226

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 8/21

6:43 pm-10:40 pm

1 stop4h 57m

Panama City NW Florida Beaches

Tue 8/25

6:40 am-2:10 pm

1 stop6h 30m

$227

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 9/9

6:25 am-3:40 pm

1 stop10h 15m

Panama City NW Florida Beaches

Sat 9/12

10:40 am-5:40 pm

2 stops6h 00m

$231

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Thu 8/20

6:43 pm-10:40 pm

1 stop4h 57m

Panama City NW Florida Beaches

Mon 8/24

5:48 pm-11:32 pm

1 stop4h 44m

$232

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 9/16

6:25 am-3:40 pm

1 stop10h 15m

Panama City NW Florida Beaches

Sat 9/19

7:15 am-12:45 pm

1 stop4h 30m

$233

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 9/16

8:45 am-3:40 pm

2 stops7h 55m

Panama City NW Florida Beaches

Sat 9/19

10:30 am-5:40 pm

2 stops6h 10m

$238

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit is in June. Flight prices, which tend to average around $119, are often lower during this time because this is during the off-season. The month of October is another great option to travel to Panama City, Florida, with average flight prices from Detroit averaging around $179.

What is the cheapest Detroit to Panama City NW Florida Beaches flight route?

Fly from Detroit Metropolitan Wayne County to Panama City NW Florida Beaches for the best Detroit - Panama City NW Florida Beaches flight prices

How far in advance should I book a flight from Detroit to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $371 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit for as low as $264 on momondo.

What cabin class options are available on Detroit to Panama City, Florida flights?

There are 2 cabin classes available to choose from on Detroit to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

When to book flights from Detroit to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City, Florida (DTT to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City, Florida

Fastest flight time

4h 30m

Direct flights

None
The fastest flight from Detroit to Panama City, Florida takes 4h 30m
There are no direct flights from Detroit to Panama City, Florida. There are no popular flight routes from Detroit to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Detroit to Panama City, Florida

  • How far is Detroit to Panama City NW Florida Beaches by plane?

    A flight from Detroit to Panama City NW Florida Beaches will travel around 853.2 mi. By plane, this route typically takes 4h 30m.

  • When did momondo last update prices for flights from Detroit to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Detroit to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Detroit to Panama City, Florida?

  • What is the most popular airline from Detroit to Panama City, Florida?

Best airlines flying from Detroit to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $208Free CancellationRating
7.8
8,457 reviews
Search Delta flights
SouthwestPriceFrom $228Free CancellationRating
7.9
4,248 reviews
Search Southwest flights
American AirlinesPriceFrom $238Free CancellationRating
7.1
11,806 reviews
Search American Airlines flights
United AirlinesPriceFrom $238Free CancellationRating
7.4
9,976 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama City?

Once all potential Detroit to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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