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Cheap flights from Detroit to Panama City from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 7/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:36 pm - 6:22 pm
DTW
-
ECP
5h 46m
1 stop
American Airlines Logo
6:54 pm - 12:41 am
ECP
-
DTW
4h 47m
1 stop
$315American Airlines
Thu, Jul 9 - Mon, Jul 20
Delta Logo
7:45 pm - 10:46 pm
DTW
-
ECP
4h 01m
1 stop
Delta Logo
6:00 am - 11:22 am
ECP
-
DTW
4h 22m
1 stop
$319Delta
Fri, Oct 2 - Sun, Oct 11
American Airlines Logo
7:58 pm - 11:40 pm
DTW
-
ECP
4h 42m
1 stop
American Airlines Logo
6:45 pm - 12:33 am
ECP
-
DTW
4h 48m
1 stop
$320American Airlines
Fri, Jun 19 - Thu, Jun 25
American Airlines Logo
10:53 am - 6:22 pm
DTW
-
ECP
8h 29m
2 stops
American Airlines Logo
6:54 pm - 12:41 am
ECP
-
DTW
4h 47m
1 stop
$324American Airlines
Wed, Jul 15 - Wed, Jul 22
American Airlines Logo
1:43 pm - 6:26 pm
DTW
-
ECP
5h 43m
1 stop
American Airlines Logo
4:16 pm - 12:33 am
ECP
-
DTW
7h 17m
1 stop
$325American Airlines
Tue, Jun 9 - Tue, Jun 16
American Airlines Logo
4:23 pm - 11:38 pm
DTW
-
ECP
8h 15m
2 stops
American Airlines Logo
7:10 am - 3:53 pm
ECP
-
DTW
7h 43m
2 stops
$329American Airlines
Sat, Aug 15 - Sat, Aug 22
American Airlines Logo
4:14 pm - 11:40 pm
DTW
-
ECP
8h 26m
2 stops
American Airlines Logo
4:16 pm - 12:33 am
ECP
-
DTW
7h 17m
1 stop
$330American Airlines
Tue, Jun 9 - Tue, Jun 16
American Airlines Logo
10:33 am - 2:33 pm
DTW
-
ECP
5h 00m
1 stop
American Airlines Logo
3:23 pm - 10:38 pm
ECP
-
DTW
6h 15m
1 stop
$331American Airlines
Tue, Jun 9 - Tue, Jun 16
American Airlines Logo
5:29 pm - 11:40 pm
DTW
-
ECP
7h 11m
2 stops
American Airlines Logo
11:00 am - 9:34 pm
ECP
-
DTW
9h 34m
2 stops
$335American Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
10:33 am - 6:26 pm
DTW
-
ECP
8h 53m
2 stops
American Airlines Logo
3:03 pm - 9:34 pm
ECP
-
DTW
5h 31m
1 stop
$336American Airlines
Tue, Jun 9 - Tue, Jun 16

American Airlines flights from Detroit to Panama City, Florida

Our best American Airlines deals on Detroit to Panama City, Florida flight tickets
American Airlines
Jul 9
DTW1:36 pmDetroit Metropolitan Wayne County
5h 46m
1 stop
ECP6:22 pmPanama City NW Florida Beaches
Jul 20
ECP6:54 pmPanama City NW Florida Beaches
4h 47m
1 stop
DTW12:41 amDetroit Metropolitan Wayne County
$315
American Airlines
Jun 19
DTW7:58 pmDetroit Metropolitan Wayne County
4h 42m
1 stop
ECP11:40 pmPanama City NW Florida Beaches
Jun 25
ECP6:45 pmPanama City NW Florida Beaches
4h 48m
1 stop
DTW12:33 amDetroit Metropolitan Wayne County
$320
American Airlines
Jul 15
DTW10:53 amDetroit Metropolitan Wayne County
8h 29m
2 stops
ECP6:22 pmPanama City NW Florida Beaches
Jul 22
ECP6:54 pmPanama City NW Florida Beaches
4h 47m
1 stop
DTW12:41 amDetroit Metropolitan Wayne County
$324

Delta flights from Detroit to Panama City, Florida

Our best Delta deals on Detroit to Panama City, Florida flight tickets
Delta
Oct 2
DTW7:45 pmDetroit Metropolitan Wayne County
4h 01m
1 stop
ECP10:46 pmPanama City NW Florida Beaches
Oct 11
ECP6:00 amPanama City NW Florida Beaches
4h 22m
1 stop
DTW11:22 amDetroit Metropolitan Wayne County
$319
Delta
Jun 9
DTW7:25 amDetroit Metropolitan Wayne County
4h 29m
1 stop
ECP10:54 amPanama City NW Florida Beaches
Jun 16
ECP5:08 pmPanama City NW Florida Beaches
4h 46m
1 stop
DTW10:54 pmDetroit Metropolitan Wayne County
$339
Delta
Oct 1
DTW7:45 pmDetroit Metropolitan Wayne County
4h 01m
1 stop
ECP10:46 pmPanama City NW Florida Beaches
Oct 7
ECP6:00 amPanama City NW Florida Beaches
4h 22m
1 stop
DTW11:22 amDetroit Metropolitan Wayne County
$368

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from Detroit to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Thu 7/9

1:36 pm-6:22 pm

1 stop5h 46m

Panama City NW Florida Beaches

Mon 7/20

6:54 pm-12:41 am

1 stop4h 47m

$315
Quickest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 10/2

7:45 pm-10:46 pm

1 stop4h 01m

Panama City NW Florida Beaches

Sun 10/11

6:00 am-11:22 am

1 stop4h 22m

$319

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 6/19

7:58 pm-11:40 pm

1 stop4h 42m

Panama City NW Florida Beaches

Thu 6/25

6:45 pm-12:33 am

1 stop4h 48m

$320

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 7/15

10:53 am-6:22 pm

2 stops8h 29m

Panama City NW Florida Beaches

Wed 7/22

6:54 pm-12:41 am

1 stop4h 47m

$324

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 6/9

1:43 pm-6:26 pm

1 stop5h 43m

Panama City NW Florida Beaches

Tue 6/16

4:16 pm-12:33 am

1 stop7h 17m

$325

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 8/15

4:23 pm-11:38 pm

2 stops8h 15m

Panama City NW Florida Beaches

Sat 8/22

7:10 am-3:53 pm

2 stops7h 43m

$329

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 6/9

4:14 pm-11:40 pm

2 stops8h 26m

Panama City NW Florida Beaches

Tue 6/16

4:16 pm-12:33 am

1 stop7h 17m

$330

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 6/9

10:33 am-2:33 pm

1 stop5h 00m

Panama City NW Florida Beaches

Tue 6/16

3:23 pm-10:38 pm

1 stop6h 15m

$331

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 6/16

5:29 pm-11:40 pm

2 stops7h 11m

Panama City NW Florida Beaches

Tue 6/23

11:00 am-9:34 pm

2 stops9h 34m

$335

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 6/9

10:33 am-6:26 pm

2 stops8h 53m

Panama City NW Florida Beaches

Tue 6/16

3:03 pm-9:34 pm

1 stop5h 31m

$336

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit is in May. Flight prices, which tend to average around $108, are often lower during this time because this is during the off-season. The month of June is another great option to travel to Panama City, Florida, with average flight prices from Detroit averaging around $119.

How far in advance should I book a flight from Detroit to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $343 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit for as low as $247 on momondo.

When to book flights from Detroit to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City, Florida (DTT to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City, Florida

Fastest flight time

3h 50m

Direct flights

None
The fastest flight from Detroit to Panama City, Florida takes 3h 50m
There are no direct flights from Detroit to Panama City, Florida. There are no popular flight routes from Detroit to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Detroit to Panama City, Florida

  • How far is Detroit to Panama City NW Florida Beaches by plane?

    A flight from Detroit to Panama City NW Florida Beaches will travel around 853.2 mi. By plane, this route typically takes 3h 50m.

  • When did momondo last update prices for flights from Detroit to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Detroit to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Detroit to Panama City, Florida?

  • What is the most popular airline from Detroit to Panama City, Florida?

Best airlines flying from Detroit to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,452 reviews
Search Delta flights
SouthwestPriceFrom $228Free CancellationRating
7.9
4,282 reviews
Search Southwest flights
American AirlinesPriceFrom $237Free CancellationRating
7.1
11,641 reviews
Search American Airlines flights
United AirlinesPriceFrom $238Free CancellationRating
7.4
9,748 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama City?

Once all potential Detroit to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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