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Cheap flights from Detroit to Panama City from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Delta Logo
12:17 pm - 3:53 pmDTW-ECP
4h 36m1 stop
Delta Logo
4:26 pm - 10:57 pmECP-DTW
5h 31m1 stop
$239Delta
Find Deal
jue., dic. 11 - lun., dic. 15
American Airlines Logo
6:40 pm - 10:53 pmDTW-ECP
5h 13m1 stop
American Airlines Logo
8:21 am - 7:14 pmECP-DTW
9h 53m2 stops
$244American Airlines
Find Deal
jue., oct. 30 - mar., nov. 4
United Airlines Logo
6:00 am - 4:16 pmDTW-ECP
11h 16m2 stops
United Airlines Logo
6:30 am - 4:57 pmECP-DTW
9h 27m2 stops
$249United Airlines
Find Deal
sáb., oct. 25 - sáb., nov. 1
Southwest Logo
6:00 am - 9:05 amDTW-ECP
4h 05m1 stop
Southwest Logo
9:40 am - 11:40 pmECP-DTW
13h 00m2 stops
$250Southwest
Find Deal
dom., nov. 9 - vie., nov. 14
Delta Logo
5:56 pm - 11:10 pmDTW-ECP
6h 14m1 stop
Delta Logo
5:32 pm - 12:41 amECP-DTW
6h 09m1 stop
$259Delta
Find Deal
lun., oct. 6 - mié., oct. 15
Southwest Logo
5:40 am - 9:15 amDTW-ECP
4h 35m1 stop
Southwest Logo
1:30 pm - 12:20 amECP-DTW
9h 50m2 stops
$264Southwest
Find Deal
mar., nov. 25 - mié., nov. 26
Southwest Logo
5:40 am - 12:10 pmDTW-ECP
7h 30m2 stops
Southwest Logo
1:30 pm - 12:20 amECP-DTW
9h 50m2 stops
$269Southwest
Find Deal
mar., nov. 25 - mié., nov. 26
Southwest Logo
6:15 am - 2:30 pmDTW-ECP
9h 15m1 stop
Southwest Logo
12:00 pm - 10:15 pmECP-DTW
9h 15m2 stops
$270Southwest
Find Deal
mié., oct. 22 - sáb., nov. 1
American Airlines Logo
6:40 pm - 10:53 pmDTW-ECP
5h 13m1 stop
American Airlines Logo
5:30 am - 11:18 amECP-DTW
4h 48m1 stop
$278American Airlines
Find Deal
vie., oct. 24 - lun., oct. 27
United Airlines Logo
6:00 am - 1:10 pmDTW-ECP
8h 10m2 stops
United Airlines Logo
1:55 pm - 10:28 pmECP-DTW
7h 33m1 stop
$284United Airlines
Find Deal
vie., oct. 3 - mar., oct. 7

American Airlines flights from Detroit to Panama City, Florida

Our best American Airlines deals on Detroit to Panama City, Florida flight tickets
American Airlines
Oct 30
DTW6:40 pmDetroit Metropolitan Wayne County
5h 13m
1 stop
ECP10:53 pmPanama City NW Florida Beaches
Nov 4
ECP8:21 amPanama City NW Florida Beaches
9h 53m
2 stops
DTW7:14 pmDetroit Metropolitan Wayne County
$244
Find similar
American Airlines
Oct 24
DTW6:40 pmDetroit Metropolitan Wayne County
5h 13m
1 stop
ECP10:53 pmPanama City NW Florida Beaches
Oct 27
ECP5:30 amPanama City NW Florida Beaches
4h 48m
1 stop
DTW11:18 amDetroit Metropolitan Wayne County
$278
Find similar
American Airlines
Oct 6
DTW6:00 amDetroit Metropolitan Wayne County
5h 13m
1 stop
ECP10:13 amPanama City NW Florida Beaches
Oct 7
ECP3:41 pmPanama City NW Florida Beaches
6h 46m
1 stop
DTW11:27 pmDetroit Metropolitan Wayne County
$280
Find similar

Delta flights from Detroit to Panama City, Florida

Our best Delta deals on Detroit to Panama City, Florida flight tickets
Delta
Dec 11
DTW12:17 pmDetroit Metropolitan Wayne County
4h 36m
1 stop
ECP3:53 pmPanama City NW Florida Beaches
Dec 15
ECP4:26 pmPanama City NW Florida Beaches
5h 31m
1 stop
DTW10:57 pmDetroit Metropolitan Wayne County
$239
Find similar
Delta
Oct 6
DTW5:56 pmDetroit Metropolitan Wayne County
6h 14m
1 stop
ECP11:10 pmPanama City NW Florida Beaches
Oct 15
ECP5:32 pmPanama City NW Florida Beaches
6h 09m
1 stop
DTW12:41 amDetroit Metropolitan Wayne County
$259
Find similar
Delta
Oct 4
DTW7:59 pmDetroit Metropolitan Wayne County
4h 04m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Oct 8
ECP5:32 pmPanama City NW Florida Beaches
6h 09m
1 stop
DTW12:41 amDetroit Metropolitan Wayne County
$279
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Detroit to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

jue. 12/11

12:17 pm-3:53 pm

1 stop4h 36m

Panama City NW Florida Beaches

lun. 12/15

4:26 pm-10:57 pm

1 stop5h 31m

$239

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

jue. 10/30

6:40 pm-10:53 pm

1 stop5h 13m

Panama City NW Florida Beaches

mar. 11/4

8:21 am-7:14 pm

2 stops9h 53m

$244

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

sáb. 10/25

6:00 am-4:16 pm

2 stops11h 16m

Panama City NW Florida Beaches

sáb. 11/1

6:30 am-4:57 pm

2 stops9h 27m

$249

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

dom. 11/9

6:00 am-9:05 am

1 stop4h 05m

Panama City NW Florida Beaches

vie. 11/14

9:40 am-11:40 pm

2 stops13h 00m

$250

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

lun. 10/6

5:56 pm-11:10 pm

1 stop6h 14m

Panama City NW Florida Beaches

mié. 10/15

5:32 pm-12:41 am

1 stop6h 09m

$259

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

mar. 11/25

5:40 am-9:15 am

1 stop4h 35m

Panama City NW Florida Beaches

mié. 11/26

1:30 pm-12:20 am

2 stops9h 50m

$264

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

mar. 11/25

5:40 am-12:10 pm

2 stops7h 30m

Panama City NW Florida Beaches

mié. 11/26

1:30 pm-12:20 am

2 stops9h 50m

$269

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

mié. 10/22

6:15 am-2:30 pm

1 stop9h 15m

Panama City NW Florida Beaches

sáb. 11/1

12:00 pm-10:15 pm

2 stops9h 15m

$270

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

vie. 10/24

6:40 pm-10:53 pm

1 stop5h 13m

Panama City NW Florida Beaches

lun. 10/27

5:30 am-11:18 am

1 stop4h 48m

$278

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

vie. 10/3

6:00 am-1:10 pm

2 stops8h 10m

Panama City NW Florida Beaches

mar. 10/7

1:55 pm-10:28 pm

1 stop7h 33m

$284

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit is in September. Flight prices, which tend to average around $268, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Panama City, Florida, with average flight prices from Detroit averaging around $298.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $309. On the other hand, Friday is the most expensive day to depart from Detroit because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $436.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $353 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit for as low as $306 on momondo.

When to book flights from Detroit to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City, Florida (DTT to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City, Florida

Direct flights

None
There are no direct flights from Detroit to Panama City, Florida. There are no popular flight routes from Detroit to Panama City, Florida.
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  • How far is Detroit to Panama City NW Florida Beaches by plane?

    A flight from Detroit to Panama City NW Florida Beaches will travel around 853.2 mi. By plane, this route typically takes 3h 43m.

  • When did momondo last update prices for flights from Detroit to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Detroit to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Panama City, Florida?

Best airlines flying from Detroit to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $208Free CancellationRating
7.9
7,961 reviews
Search Delta flights
SouthwestPriceFrom $254Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama City?

Once all potential Detroit to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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vie. 10/17
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