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Cheap flights from Detroit to Panama City from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
6:10 am - 9:30 am
DTW
-
ECP
4h 20m
1 stop
Southwest Logo
7:20 am - 3:00 pm
ECP
-
DTW
6h 40m
1 stop
$299Southwest
Wed, Apr 29 - Sat, May 9
Southwest Logo
6:10 am - 9:30 am
DTW
-
ECP
4h 20m
1 stop
Southwest Logo
9:55 am - 9:25 pm
ECP
-
DTW
10h 30m
2 stops
$304Southwest
Wed, Apr 29 - Sat, May 9
Southwest Logo
1:40 pm - 6:55 pm
DTW
-
ECP
6h 15m
2 stops
Southwest Logo
12:05 pm - 8:15 pm
ECP
-
DTW
7h 10m
2 stops
$309Southwest
Tue, May 5 - Tue, May 12
Southwest Logo
8:40 am - 6:20 pm
DTW
-
ECP
10h 40m
2 stops
Southwest Logo
7:15 am - 12:40 pm
ECP
-
DTW
4h 25m
1 stop
$314Southwest
Fri, May 8 - Wed, May 13
Southwest Logo
6:10 am - 4:20 pm
DTW
-
ECP
11h 10m
2 stops
Southwest Logo
9:55 am - 9:25 pm
ECP
-
DTW
10h 30m
2 stops
$315Southwest
Wed, Apr 29 - Sat, May 9
United Airlines Logo
6:00 am - 12:58 pm
DTW
-
ECP
7h 58m
2 stops
United Airlines Logo
11:38 am - 10:23 pm
ECP
-
DTW
9h 45m
2 stops
$316United Airlines
Wed, Aug 26 - Wed, Sep 2
Southwest Logo
6:10 am - 9:30 am
DTW
-
ECP
4h 20m
1 stop
Southwest Logo
7:55 am - 1:05 pm
ECP
-
DTW
4h 10m
1 stop
$317Southwest
Wed, Apr 29 - Sat, May 2
Delta Logo
6:20 am - 10:48 am
DTW
-
ECP
5h 28m
1 stop
Delta Logo
6:00 am - 12:56 pm
ECP
-
DTW
5h 56m
1 stop
$319Delta
Wed, Jul 15 - Wed, Jul 22
Southwest Logo
6:10 am - 9:30 am
DTW
-
ECP
4h 20m
1 stop
Southwest Logo
12:40 pm - 11:10 pm
ECP
-
DTW
9h 30m
2 stops
$322Southwest
Wed, Apr 29 - Sat, May 2
Delta Logo
3:00 pm - 11:28 pm
DTW
-
ECP
9h 28m
1 stop
Delta Logo
2:43 pm - 8:15 pm
ECP
-
DTW
4h 32m
1 stop
$323Delta
Thu, Jun 4 - Wed, Jun 10

Southwest flights from Detroit to Panama City, Florida

Our best Southwest deals on Detroit to Panama City, Florida flight tickets
Southwest
Apr 29
DTW6:10 amDetroit Metropolitan Wayne County
4h 20m
1 stop
ECP9:30 amPanama City NW Florida Beaches
May 9
ECP7:20 amPanama City NW Florida Beaches
6h 40m
1 stop
DTW3:00 pmDetroit Metropolitan Wayne County
$299
Southwest
Apr 29
DTW6:10 amDetroit Metropolitan Wayne County
4h 20m
1 stop
ECP9:30 amPanama City NW Florida Beaches
May 9
ECP9:55 amPanama City NW Florida Beaches
10h 30m
2 stops
DTW9:25 pmDetroit Metropolitan Wayne County
$304
Southwest
May 5
DTW1:40 pmDetroit Metropolitan Wayne County
6h 15m
2 stops
ECP6:55 pmPanama City NW Florida Beaches
May 12
ECP12:05 pmPanama City NW Florida Beaches
7h 10m
2 stops
DTW8:15 pmDetroit Metropolitan Wayne County
$309

Delta flights from Detroit to Panama City, Florida

Our best Delta deals on Detroit to Panama City, Florida flight tickets
Delta
Jul 15
DTW6:20 amDetroit Metropolitan Wayne County
5h 28m
1 stop
ECP10:48 amPanama City NW Florida Beaches
Jul 22
ECP6:00 amPanama City NW Florida Beaches
5h 56m
1 stop
DTW12:56 pmDetroit Metropolitan Wayne County
$319
Delta
Jun 4
DTW3:00 pmDetroit Metropolitan Wayne County
9h 28m
1 stop
ECP11:28 pmPanama City NW Florida Beaches
Jun 10
ECP2:43 pmPanama City NW Florida Beaches
4h 32m
1 stop
DTW8:15 pmDetroit Metropolitan Wayne County
$323
Delta
Aug 26
DTW9:30 amDetroit Metropolitan Wayne County
6h 47m
1 stop
ECP3:17 pmPanama City NW Florida Beaches
Aug 29
ECP12:05 pmPanama City NW Florida Beaches
2h 32m
DTW3:37 pmDetroit Metropolitan Wayne County
$329

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Detroit to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 4/29

6:10 am-9:30 am

1 stop4h 20m

Panama City NW Florida Beaches

Sat 5/9

7:20 am-3:00 pm

1 stop6h 40m

$299

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 4/29

6:10 am-9:30 am

1 stop4h 20m

Panama City NW Florida Beaches

Sat 5/9

9:55 am-9:25 pm

2 stops10h 30m

$304

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 5/5

1:40 pm-6:55 pm

2 stops6h 15m

Panama City NW Florida Beaches

Tue 5/12

12:05 pm-8:15 pm

2 stops7h 10m

$309

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 5/8

8:40 am-6:20 pm

2 stops10h 40m

Panama City NW Florida Beaches

Wed 5/13

7:15 am-12:40 pm

1 stop4h 25m

$314

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 4/29

6:10 am-4:20 pm

2 stops11h 10m

Panama City NW Florida Beaches

Sat 5/9

9:55 am-9:25 pm

2 stops10h 30m

$315

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 8/26

6:00 am-12:58 pm

2 stops7h 58m

Panama City NW Florida Beaches

Wed 9/2

11:38 am-10:23 pm

2 stops9h 45m

$316
Quickest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 4/29

6:10 am-9:30 am

1 stop4h 20m

Panama City NW Florida Beaches

Sat 5/2

7:55 am-1:05 pm

1 stop4h 10m

$317

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 7/15

6:20 am-10:48 am

1 stop5h 28m

Panama City NW Florida Beaches

Wed 7/22

6:00 am-12:56 pm

1 stop5h 56m

$319

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 4/29

6:10 am-9:30 am

1 stop4h 20m

Panama City NW Florida Beaches

Sat 5/2

12:40 pm-11:10 pm

2 stops9h 30m

$322

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Thu 6/4

3:00 pm-11:28 pm

1 stop9h 28m

Panama City NW Florida Beaches

Wed 6/10

2:43 pm-8:15 pm

1 stop4h 32m

$323

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit is in January. Flight prices, which tend to average around $248, are often lower during this time because this is during the off-season. The month of November is another great option to travel to Panama City, Florida, with average flight prices from Detroit averaging around $248.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $342 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit for as low as $247 on momondo.

When to book flights from Detroit to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City, Florida (DTT to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City, Florida

Fastest flight time

2h 15m

Direct flights

Mon and Sun

Airports in Panama City, Florida

1 airport
The fastest flight from Detroit to Panama City, Florida takes 2h 15m
Direct flights go from Detroit to Panama City, Florida on Monday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Panama City, Florida. From Detroit there are direct flights to Panama City NW Florida Beaches (ECP).
Search flight deals

Frequently asked questions about flying from Detroit to Panama City, Florida

  • How far is Detroit to Panama City NW Florida Beaches by plane?

    A flight from Detroit to Panama City NW Florida Beaches will travel around 853.2 mi. By plane, this route typically takes 2h 15m.

  • When did momondo last update prices for flights from Detroit to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Detroit to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Detroit to Panama City, Florida?

  • What is the most popular airline from Detroit to Panama City, Florida?

Best airlines flying from Detroit to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,392 reviews
Search Delta flights
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,559 reviews
Search American Airlines flights
United AirlinesPriceFrom $238Free CancellationRating
7.4
9,554 reviews
Search United Airlines flights
SouthwestPriceFrom $238Free CancellationRating
8.0
4,338 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama City?

Once all potential Detroit to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama City, Florida trip

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