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Cheap flights from Detroit to Panama City from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 2/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
6:00 am - 9:35 am
DTW
-
ECP
4h 35m1 stop
Southwest Logo
4:40 pm - 9:45 pm
ECP
-
DTW
4h 05m1 stop
$239Southwest
Mon, Feb 9 - Sat, Feb 14
American Airlines Logo
7:54 pm - 11:52 pm
DTW
-
ECP
4h 58m1 stop
American Airlines Logo
10:20 am - 10:20 pm
ECP
-
DTW
11h 00m2 stops
$244American Airlines
Fri, Feb 20 - Tue, Feb 24
American Airlines Logo
1:08 pm - 11:52 pm
DTW
-
ECP
11h 44m2 stops
American Airlines Logo
1:50 pm - 10:46 pm
ECP
-
DTW
7h 56m2 stops
$249American Airlines
Sun, Feb 15 - Wed, Feb 18
Southwest Logo
6:30 am - 9:50 am
DTW
-
ECP
4h 20m1 stop
Southwest Logo
3:45 pm - 9:00 pm
ECP
-
DTW
4h 15m1 stop
$259Southwest
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
10:56 am - 4:12 pm
DTW
-
ECP
6h 16m1 stop
United Airlines Logo
6:30 am - 5:03 pm
ECP
-
DTW
9h 33m2 stops
$264United Airlines
Wed, Jan 21 - Wed, Jan 28
United Airlines Logo
5:30 am - 4:12 pm
DTW
-
ECP
11h 42m2 stops
United Airlines Logo
6:30 am - 8:26 pm
ECP
-
DTW
12h 56m2 stops
$269United Airlines
Wed, Jan 21 - Wed, Jan 28
United Airlines Logo
2:19 pm - 9:59 pm
DTW
-
ECP
8h 40m2 stops
United Airlines Logo
1:10 pm - 11:44 pm
ECP
-
DTW
9h 34m2 stops
$273United Airlines
Mon, Feb 2 - Tue, Feb 10
American Airlines Logo
7:54 pm - 11:49 pm
DTW
-
ECP
4h 55m1 stop
American Airlines Logo
10:31 am - 6:43 pm
ECP
-
DTW
7h 12m1 stop
$278American Airlines
Wed, Mar 11 - Sat, Mar 21
American Airlines Logo
6:00 am - 4:04 pm
DTW
-
ECP
11h 04m2 stops
American Airlines Logo
7:19 am - 2:57 pm
ECP
-
DTW
6h 38m1 stop
$283American Airlines
Wed, Mar 11 - Sat, Mar 21
American Airlines Logo
2:18 pm - 11:49 pm
DTW
-
ECP
10h 31m2 stops
American Airlines Logo
7:19 am - 6:43 pm
ECP
-
DTW
10h 24m2 stops
$288American Airlines
Wed, Mar 11 - Sat, Mar 21

American Airlines flights from Detroit to Panama City, Florida

Our best American Airlines deals on Detroit to Panama City, Florida flight tickets
American Airlines
Feb 20
DTW7:54 pmDetroit Metropolitan Wayne County
4h 58m
1 stop
ECP11:52 pmPanama City NW Florida Beaches
Feb 24
ECP10:20 amPanama City NW Florida Beaches
11h 00m
2 stops
DTW10:20 pmDetroit Metropolitan Wayne County
$244
Find similar
American Airlines
Feb 15
DTW1:08 pmDetroit Metropolitan Wayne County
11h 44m
2 stops
ECP11:52 pmPanama City NW Florida Beaches
Feb 18
ECP1:50 pmPanama City NW Florida Beaches
7h 56m
2 stops
DTW10:46 pmDetroit Metropolitan Wayne County
$249
Find similar
American Airlines
Mar 11
DTW6:00 amDetroit Metropolitan Wayne County
5h 06m
1 stop
ECP10:06 amPanama City NW Florida Beaches
Mar 21
ECP12:03 pmPanama City NW Florida Beaches
5h 40m
1 stop
DTW6:43 pmDetroit Metropolitan Wayne County
$278
Find similar

Southwest flights from Detroit to Panama City, Florida

Our best Southwest deals on Detroit to Panama City, Florida flight tickets
Southwest
Feb 9
DTW6:00 amDetroit Metropolitan Wayne County
4h 35m
1 stop
ECP9:35 amPanama City NW Florida Beaches
Feb 14
ECP4:40 pmPanama City NW Florida Beaches
4h 05m
1 stop
DTW9:45 pmDetroit Metropolitan Wayne County
$239
Find similar
Southwest
Jan 17
DTW6:30 amDetroit Metropolitan Wayne County
4h 20m
1 stop
ECP9:50 amPanama City NW Florida Beaches
Jan 21
ECP3:45 pmPanama City NW Florida Beaches
4h 15m
1 stop
DTW9:00 pmDetroit Metropolitan Wayne County
$259
Find similar
Southwest
Feb 19
DTW6:00 amDetroit Metropolitan Wayne County
4h 35m
1 stop
ECP9:35 amPanama City NW Florida Beaches
Feb 24
ECP8:00 amPanama City NW Florida Beaches
6h 05m
1 stop
DTW3:05 pmDetroit Metropolitan Wayne County
$289
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Detroit to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Mon 2/9

6:00 am-9:35 am

1 stop4h 35m

Panama City NW Florida Beaches

Sat 2/14

4:40 pm-9:45 pm

1 stop4h 05m

$239

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 2/20

7:54 pm-11:52 pm

1 stop4h 58m

Panama City NW Florida Beaches

Tue 2/24

10:20 am-10:20 pm

2 stops11h 00m

$244

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sun 2/15

1:08 pm-11:52 pm

2 stops11h 44m

Panama City NW Florida Beaches

Wed 2/18

1:50 pm-10:46 pm

2 stops7h 56m

$249

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 1/17

6:30 am-9:50 am

1 stop4h 20m

Panama City NW Florida Beaches

Wed 1/21

3:45 pm-9:00 pm

1 stop4h 15m

$259

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 1/21

10:56 am-4:12 pm

1 stop6h 16m

Panama City NW Florida Beaches

Wed 1/28

6:30 am-5:03 pm

2 stops9h 33m

$264

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 1/21

5:30 am-4:12 pm

2 stops11h 42m

Panama City NW Florida Beaches

Wed 1/28

6:30 am-8:26 pm

2 stops12h 56m

$269

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Mon 2/2

2:19 pm-9:59 pm

2 stops8h 40m

Panama City NW Florida Beaches

Tue 2/10

1:10 pm-11:44 pm

2 stops9h 34m

$273

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 3/11

7:54 pm-11:49 pm

1 stop4h 55m

Panama City NW Florida Beaches

Sat 3/21

10:31 am-6:43 pm

1 stop7h 12m

$278

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 3/11

6:00 am-4:04 pm

2 stops11h 04m

Panama City NW Florida Beaches

Sat 3/21

7:19 am-2:57 pm

1 stop6h 38m

$283

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 3/11

2:18 pm-11:49 pm

2 stops10h 31m

Panama City NW Florida Beaches

Sat 3/21

7:19 am-6:43 pm

2 stops10h 24m

$288

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit is in September. Flight prices, which tend to average around $268, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Panama City, Florida, with average flight prices from Detroit averaging around $298.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $309. On the other hand, Friday is the most expensive day to depart from Detroit because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $436.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $355 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit for as low as $238 on momondo.

When to book flights from Detroit to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City, Florida (DTT to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City, Florida

Fastest flight time

4h 00m

Direct flights

None
The fastest flight from Detroit to Panama City, Florida takes 4h 00m
There are no direct flights from Detroit to Panama City, Florida. There are no popular flight routes from Detroit to Panama City, Florida.
Search flight deals

  • How far is Detroit to Panama City NW Florida Beaches by plane?

    A flight from Detroit to Panama City NW Florida Beaches will travel around 853.2 mi. By plane, this route typically takes 4h 00m.

  • When did momondo last update prices for flights from Detroit to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Detroit to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Panama City, Florida?

Best airlines flying from Detroit to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,019 reviews
Search Delta flights
SouthwestPriceFrom $238Free CancellationRating
8.0
4,256 reviews
Search Southwest flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,073 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama City?

Once all potential Detroit to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama City, Florida trip

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