Cheap flights from Detroit to Panama City from $110
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 10/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Mon 11/9
6:25 pm-10:52 pm
1 stop5h 27m
Panama City NW Florida Beaches
Sat 11/21
6:49 pm-12:37 am
1 stop4h 48m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Tue 10/27
6:10 am-11:38 am
1 stop6h 28m
Panama City NW Florida Beaches
Tue 11/3
5:41 pm-11:28 pm
1 stop4h 47m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Tue 12/1
6:00 am-9:30 am
1 stop4h 30m
Panama City NW Florida Beaches
Mon 12/7
4:10 pm-9:20 pm
1 stop4h 10m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Mon 2/15
8:42 am-1:22 pm
1 stop5h 40m
Panama City NW Florida Beaches
Tue 3/2
2:10 pm-10:26 pm
1 stop7h 16m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Thu 2/25
8:42 am-1:22 pm
1 stop5h 40m
Panama City NW Florida Beaches
Wed 3/3
2:10 pm-10:26 pm
1 stop7h 16m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Tue 2/9
6:00 am-11:32 am
1 stop6h 32m
Panama City NW Florida Beaches
Wed 2/24
11:09 am-8:06 pm
1 stop7h 57m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Tue 2/9
6:15 am-9:45 am
1 stop4h 30m
Panama City NW Florida Beaches
Wed 2/24
7:55 am-3:55 pm
2 stops7h 00m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Tue 12/1
6:55 am-3:35 pm
2 stops9h 40m
Panama City NW Florida Beaches
Mon 12/7
4:10 pm-9:20 pm
1 stop4h 10m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Wed 2/17
3:55 pm-7:36 pm
1 stop4h 41m
Panama City NW Florida Beaches
Wed 3/3
6:00 am-12:34 pm
1 stop5h 34m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Tue 2/16
3:55 pm-7:36 pm
1 stop4h 41m
Panama City NW Florida Beaches
Wed 3/3
7:45 am-3:11 pm
1 stop6h 26m
See travel insights to Panama City from
How to get the cheapest flight ticket from Detroit to Panama City, Florida
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Panama City, Florida?
The cheapest month to fly to Panama City, Florida from Detroit is in January. Flight prices, which tend to average around $285, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from Detroit averaging around $321.
What is the cheapest Detroit to Panama City NW Florida Beaches flight route?
Fly from Detroit Metropolitan Wayne County to Panama City NW Florida Beaches for the best Detroit - Panama City NW Florida Beaches flight prices
How far in advance should I book a flight from Detroit to Panama City, Florida?
You are more likely to see cheaper flights to Panama City, Florida from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $426 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit for as low as $312 on momondo.
What cabin class options are available on Detroit to Panama City, Florida flights?
There are 2 cabin classes available to choose from on Detroit to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
What is the cheapest airline that flies from Detroit to Panama City NW Florida Beaches?
Southwest and Delta are the most popular carriers operating from Detroit to Panama City NW Florida Beaches
What airlines fly to Panama City, Florida?
Delta, American Airlines and Southwest are the top three most popular airlines that fly to Panama City, Florida from Detroit according to our data. Delta is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 5 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.
Which airport is the most popular layover for flights between Detroit and Panama City, Florida?
Nashville (BNA) was the most common stop: 44% of momondo users choosing 1-stop flights on this route connected there.
Which layover airport offers the lowest fares from Detroit to Panama City, Florida?
Flights via Chicago (ORD) offer the lowest average round-trip price of $238.
Which layover airport has the shortest travel time from Detroit to Panama City, Florida?
Flights connecting via Nashville (BNA) have the shortest average one-way travel time: 4h 42m.
Which layover airport has the shortest connection time from Detroit to Panama City, Florida?
Chicago (ORD) has the shortest average layover time for this route: 0h 53m.
When to book flights from Detroit to Panama City, Florida
Cheap Detroit to Panama City, Florida (DTT to ECP) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City, Florida
Frequently asked questions about flying from Detroit to Panama City, Florida
How far is Detroit to Panama City NW Florida Beaches by plane?
A flight from Detroit to Panama City NW Florida Beaches will travel around 853.2 mi. By plane, this route typically takes 4h 00m.
When did momondo last update prices for flights from Detroit to Panama City NW Florida Beaches Airport?
Prices for flights from Detroit to Panama City NW Florida Beaches Airport were last updated today.
How many operators does momondo search for flights from Detroit to Panama City NW Florida Beaches Airport?
The number of operators available for flights from Detroit to Panama City NW Florida Beaches Airport is 4 as of October 2026.
How old do you have to be to fly from Detroit to Panama City NW Florida Beaches Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to Panama City NW Florida Beaches Airport.
What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?
The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Detroit to Panama City, Florida?
Based on momondo bookings for flights between Detroit and Panama City, Florida, the leading plane model is Boeing 717-200, making up 100.00% of the total bookings.
What is the most popular airline from Detroit to Panama City, Florida?
momondo data reveals that the most frequently booked airline on the route from Detroit to Panama City, Florida is Southwest, representing 43% of all bookings. The subsequent popular airlines are Delta at 34% and American Airlines at 23%.
Best airlines flying from Detroit to Panama City, Florida
Compare and see reviews for airlines that fly from Detroit to Panama City, Florida with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $239 | Free Cancellation | Rating 7.0 12,146 reviews | |||
| PriceFrom $239 | Free Cancellation | Rating 7.8 8,646 reviews | |||
| PriceFrom $258 | Free Cancellation | Rating 7.9 4,224 reviews | |||
| PriceFrom $278 | Free Cancellation | Rating 7.4 10,322 reviews |
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Detroit to Panama City?
To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.
Can I find flights from Detroit to Panama City with flexible booking policies on momondo?
momondo does allow users to show only those flights to Panama City from Detroit which offer a flexible booking policy as well as other useful filters and features.
How can momondo help me find flights from Detroit to Panama City?
Once all potential Detroit to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.
I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?
Yes momondo offers price alerts on flights to Panama City from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.