What airlines fly to San Francisco Bay Area?

American Airlines, Southwest and United Airlines are the top three most popular airlines that fly to San Francisco Bay Area from Des Moines according to our data. American Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to San Francisco Bay Area. Keep in mind that there are 5 different airlines that fly to San Francisco Bay Area on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to San Francisco Bay Area?

American Airlines, Delta, and Southwest are the most popular carriers operating from Des Moines to San Francisco Bay Area

When did momondo last update prices for flights from Des Moines Airport to San Francisco Bay Area?

Prices for flights from Des Moines Airport to San Francisco Bay Area are refreshed on a daily basis.

How many operators does momondo search for flights from Des Moines Airport to San Francisco Bay Area?

There are 5 operators available for flights from Des Moines Airport to San Francisco Bay Area as of March 2026.

How old do you have to be to fly from Des Moines Airport to San Francisco Bay Area?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to San Francisco Bay Area.

What documentation or ID do you need to fly to San Francisco Bay Area?

The travel and health documents you'll need for your trip to San Francisco Bay Area may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Bay Area. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$117 Cheap Flights from Des Moines to San Francisco Bay Area in 2026

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Find the cheapest flights from Des Moines to San Francisco Bay Area

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:04 pm - 12:27 am

DSM

SFO

12h 23m

1 stop

7:40 pm - 6:01 pm

SFO

DSM

20h 21m

1 stop

$216Multiple Airlines

週五, 4月 17 - 週三, 4月 22

8:14 pm - 12:23 am

DSM

SFO

6h 09m

1 stop

9:05 pm - 7:14 pm

SFO

DSM

20h 09m

1 stop

$221Frontier

週五, 4月 3 - 週四, 4月 9

8:21 pm - 12:28 am

DSM

SFO

6h 07m

1 stop

9:04 pm - 7:16 pm

SFO

DSM

20h 12m

1 stop

$231Frontier

週五, 3月 20 - 週二, 3月 24

2:04 pm - 9:39 pm

DSM

SFO

33h 35m

2 stops

7:40 pm - 6:01 pm

SFO

DSM

20h 21m

1 stop

$232Multiple Airlines

週五, 4月 17 - 週三, 4月 22

2:44 pm - 9:45 pm

DSM

SJC

9h 01m

1 stop

6:20 am - 3:41 pm

SJC

DSM

7h 21m

1 stop

$285Delta

週二, 4月 21 - 週二, 4月 28

2:44 pm - 9:45 pm

DSM

SJC

9h 01m

1 stop

8:20 pm - 10:16 am

SJC

DSM

11h 56m

2 stops

$290Delta

週二, 4月 21 - 週二, 4月 28

5:30 am - 12:55 pm

DSM

SJC

9h 25m

1 stop

6:35 am - 2:05 pm

SJC

DSM

5h 30m

1 stop

$317Southwest

週二, 4月 14 - 週二, 4月 21

3:15 pm - 10:10 pm

DSM

SJC

8h 55m

2 stops

6:35 am - 2:05 pm

SJC

DSM

5h 30m

1 stop

$322Southwest

週二, 4月 14 - 週二, 4月 21

5:30 am - 12:35 pm

DSM

STS

9h 05m

1 stop

12:17 pm - 11:03 pm

STS

DSM

8h 46m

1 stop

$479American Airlines

週三, 8月 12 - 週二, 8月 18

5:12 am - 3:46 pm

DSM

STS

12h 34m

2 stops

4:17 pm - 12:22 am

STS

DSM

6h 05m

1 stop

$484American Airlines

週三, 8月 12 - 週二, 8月 18

Frontier flights from Des Moines to San Francisco Bay Area

Our best Frontier deals on Des Moines to San Francisco Bay Area flight tickets

Frontier

Apr 3

DSM8:14 pmDes Moines

6h 09m

1 stop

SFO12:23 amSan Francisco

Apr 9

SFO9:05 pmSan Francisco

20h 09m

1 stop

DSM7:14 pmDes Moines

$221

Frontier

Mar 23

DSM8:21 pmDes Moines

25h 48m

1 stop

SFO8:09 pmSan Francisco

Mar 27

SFO9:04 pmSan Francisco

20h 12m

1 stop

DSM7:16 pmDes Moines

$250

Frontier

Apr 3

DSM8:14 pmDes Moines

26h 46m

2 stops

SFO9:00 pmSan Francisco

Apr 6

SFO6:00 amSan Francisco

11h 14m

1 stop

DSM7:14 pmDes Moines

$257

Delta flights from Des Moines to San Francisco Bay Area

Our best Delta deals on Des Moines to San Francisco Bay Area flight tickets

Delta

Apr 21

DSM2:44 pmDes Moines

9h 01m

1 stop

SJC9:45 pmSan Jose

Apr 28

SJC6:20 amSan Jose

7h 21m

1 stop

DSM3:41 pmDes Moines

$285

Delta

Apr 21

DSM2:44 pmDes Moines

9h 01m

1 stop

SJC9:45 pmSan Jose

Apr 28

SJC8:20 pmSan Jose

11h 56m

2 stops

DSM10:16 amDes Moines

$290

Delta

Apr 14

DSM6:31 pmDes Moines

15h 14m

2 stops

SFO7:45 amSan Francisco

Apr 15

SFO1:10 pmSan Francisco

19h 06m

2 stops

DSM10:16 amDes Moines

$294

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to San Francisco Bay Area that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

週五 4/17

2:04 pm-12:27 am

1 stop12h 23m

San Francisco

週三 4/22

7:40 pm-6:01 pm

1 stop20h 21m

$216

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

週五 4/3

8:14 pm-12:23 am

1 stop6h 09m

San Francisco

週四 4/9

9:05 pm-7:14 pm

1 stop20h 09m

$221

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

週五 3/20

8:21 pm-12:28 am

1 stop6h 07m

San Francisco

週二 3/24

9:04 pm-7:16 pm

1 stop20h 12m

$231

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

週五 4/17

2:04 pm-9:39 pm

2 stops33h 35m

San Francisco

週三 4/22

7:40 pm-6:01 pm

1 stop20h 21m

$232

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

週二 4/21

2:44 pm-9:45 pm

1 stop9h 01m

San Jose

週二 4/28

6:20 am-3:41 pm

1 stop7h 21m

$285

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

週二 4/21

2:44 pm-9:45 pm

1 stop9h 01m

San Jose

週二 4/28

8:20 pm-10:16 am

2 stops11h 56m

$290

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

週二 4/14

5:30 am-12:55 pm

1 stop9h 25m

San Jose

週二 4/21

6:35 am-2:05 pm

1 stop5h 30m

$317

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

週二 4/14

3:15 pm-10:10 pm

2 stops8h 55m

San Jose

週二 4/21

6:35 am-2:05 pm

1 stop5h 30m

$322

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

週三 8/12

5:30 am-12:35 pm

1 stop9h 05m

Santa Rosa Sonoma County

週二 8/18

12:17 pm-11:03 pm

1 stop8h 46m

$479

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

週三 8/12

5:12 am-3:46 pm

2 stops12h 34m

Santa Rosa Sonoma County

週二 8/18

4:17 pm-12:22 am

1 stop6h 05m

$484

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to San Francisco Bay Area

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to San Francisco Bay Area?

In general, September is the cheapest month to fly from Des Moines to San Francisco Bay Area. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you aren’t able to travel to San Francisco Bay Area during the month of September, then flying in December is also cheap. Prices for this month can be found on momondo for an average of $386.

How far in advance should I book a flight to San Francisco Bay Area?

You are more likely to see cheaper flights to San Francisco Bay Area from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco Bay Area for around $426 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco Bay Area from Des Moines for as low as $352 on momondo.

Can stopping save me money on Des Moines to San Francisco Bay Area flights?

No. A direct flight is the cheapest option for a flight between Des Moines to San Francisco Bay Area.

Cheap Des Moines to San Francisco Bay Area flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Francisco Bay Area

Fastest flight time	5h 20m
Direct flights	None

The fastest flight from Des Moines to San Francisco Bay Area takes 5h 20m

There are no direct flights from Des Moines to San Francisco Bay Area. There are no popular flight routes from Des Moines to San Francisco Bay Area.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to San Francisco Bay Area?
Prices for flights from Des Moines Airport to San Francisco Bay Area are refreshed on a daily basis.
How many operators does momondo search for flights from Des Moines Airport to San Francisco Bay Area?
There are 5 operators available for flights from Des Moines Airport to San Francisco Bay Area as of March 2026.
How old do you have to be to fly from Des Moines Airport to San Francisco Bay Area?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to San Francisco Bay Area.
What documentation or ID do you need to fly to San Francisco Bay Area?
The travel and health documents you'll need for your trip to San Francisco Bay Area may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Bay Area. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Des Moines to San Francisco Bay Area?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Des Moines to San Francisco Bay Area is Airbus A320-100/200 (25.04% of total bookings). The next most popular plane models are Airbus A319 (15.92%), Embraer 175 (13.69%), and Boeing 737 MAX 8 (9.48%).

Best airlines flying from Des Moines to San Francisco Bay Area

Compare and see reviews for airlines that fly from Des Moines to San Francisco Bay Area with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $158	Free Cancellation	Rating 5.7 3,040 reviews	Search Frontier flights
Delta	PriceFrom $179	Free Cancellation	Rating 7.9 8,237 reviews	Search Delta flights
American Airlines	PriceFrom $290	Free Cancellation	Rating 7.1 11,369 reviews	Search American Airlines flights
United Airlines	PriceFrom $296	Free Cancellation	Rating 7.4 9,375 reviews	Search United Airlines flights
Southwest	PriceFrom $330	Free Cancellation	Rating 8.0 4,306 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Francisco Bay Area?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to San Francisco Bay Area. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to San Francisco Bay Area with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco Bay Area from Des Moines with this policy.

How can momondo help me find flights from Des Moines to San Francisco Bay Area?

momondo provides multiple filters to help you find the best flight to San Francisco Bay Area from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Francisco Bay Area right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to San Francisco Bay Area flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.